Academic literature on the topic 'Anti-D antibody'

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Journal articles on the topic "Anti-D antibody"

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Merron, B. M., K. Maguire, and K. Morris. "When is an anti-D antibody not an anti-D antibody?" Transfusion Medicine 25, no. 2 (2015): 115–17. http://dx.doi.org/10.1111/tme.12200.

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Bachegowda, Lohith S., Yan H. Cheng, Thomas Long, and Beth H. Shaz. "Impact of Uniform Methods on Interlaboratory Antibody Titration Variability: Antibody Titration and Uniform Methods." Archives of Pathology & Laboratory Medicine 141, no. 1 (2016): 131–38. http://dx.doi.org/10.5858/arpa.2015-0351-oa.

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Context.—Substantial variability between different antibody titration methods prompted development and introduction of uniform methods in 2008. Objective.—To determine whether uniform methods consistently decrease interlaboratory variation in proficiency testing. Design.—Proficiency testing data for antibody titration between 2009 and 2013 were obtained from the College of American Pathologists. Each laboratory was supplied plasma and red cells to determine anti-A and anti-D antibody titers by their standard method: gel or tube by uniform or other methods at different testing phases (immediate
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Vildanova, N. S., E. S. Kormshchikova, E. N. Kalinina, K. A. Vorobiev, I. V. Paramonov, and E. Yu Kudasheva. "Human anti-D immunoglobulin preparations: potency standardisation milestones." Biological Products. Prevention, Diagnosis, Treatment 22, no. 3 (2022): 241–48. http://dx.doi.org/10.30895/2221-996x-2022-22-3-241-248.

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Human anti-D immunoglobulin preparations derived from human immune plasma are much needed and highly effective for specific anti-D prevention of perinatal complications and treatment of primary immune thrombocytopenia. The effectiveness of immune suppression is a direct function of the active ingredient dose received with the medicinal product. To improve the accuracy of anti-D antibody quantification, it is recommended to use certified reference materials with values assigned in international units (IUs). The aim of this study was to analyse the main stages in the development of the internati
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Muller, Corinna L., Jodi L. Schucker, and Fouad N. Boctor. "When anti-G and anti-C antibodies masquerade as anti-D antibody." Journal of Maternal-Fetal & Neonatal Medicine 24, no. 1 (2010): 193–94. http://dx.doi.org/10.3109/14767058.2010.482616.

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Brinc, Davor, and Alan H. Lazarus. "Mechanisms of anti-D action in the prevention of hemolytic disease of the fetus and newborn." Hematology 2009, no. 1 (2009): 185–91. http://dx.doi.org/10.1182/asheducation-2009.1.185.

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Abstract Anti-D is routinely and effectively used to prevent hemolytic disease of the fetus and newborn (HDFN) caused by the antibody response to the D antigen on fetal RBCs. Anti-D is a polyclonal IgG product purified from the plasma of D-alloimmunized individuals. The mechanism of anti-D has not been fully elucidated. Antigenic epitopes are not fully masked by anti-D and are available for immune system recognition. However, a correlation has frequently been observed between anti-D-mediated RBC clearance and prevention of the antibody response, suggesting that anti-D may be able to destroy RB
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Mathiesen, Line, Leif K. Nielsen, Jan Terje Andersen, et al. "Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions." Blood 122, no. 7 (2013): 1174–81. http://dx.doi.org/10.1182/blood-2012-12-473843.

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Key Points Retained FcRn binding of an IgG3 antibody devoid of FcgR and C1q binding, cellular cytotoxicity and complement activation. Inhibition of pathogenic polyclonal anti-D in antibody-dependent cellular toxicity by a hinge region deleted anti-D IgG3 antibody with efficient transplacental transport capacity.
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Sinha, Ayesha, Najla Haneefa Basheela, Durba Biswas, Debapriya Basu, and Suvro Sankha Datta. "A Rare Case of Pregnancy-induced Anti-D, Anti-C, and Anti-G Antibodies." Global Journal of Transfusion Medicine 9, no. 1 (2024): 70–72. http://dx.doi.org/10.4103/gjtm.gjtm_62_23.

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ABSTRACT A 39-year-old female with breast carcinoma presented with complaints of menorrhagia and weakness. At current admission, her hemoglobin was 6.2 g/dL, and a requisition for packed red blood cells (PRBCs) was sent to the blood center. There was no previous history of transfusions, and the last pregnancy was 11 years ago. During the immunohematological (IH) workup, she was typed as O, ccdee, with an extra reaction in reverse grouping. Her antibody screening was positive, followed by the antibody identification, which was suggestive of anti-D and anti-C antibodies. The “Rhesus G” is an imm
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Hensley, Jennifer G., Katherine P. Coughlin, and Laura L. Klein. "A Curious Case of Anti‐D Antibody Titer." Journal of Midwifery & Women's Health 54, no. 6 (2009): 497–502. http://dx.doi.org/10.1016/j.jmwh.2009.08.006.

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Bajwa, Hussan, Maqbool Alam, Muhammad Ali Rathore, and Muhammad Sajid Yazdani. "Rh Alloantibodies in Rh D Negative Blood Group Pregnant Women - A Regional Transfusion Centre Study." Pakistan Armed Forces Medical Journal 72, no. 3 (2022): 939–42. http://dx.doi.org/10.51253/pafmj.v72i3.5124.

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Objective: To determine the frequency of Rh alloantibodies in pregnant women of the Rh-D negative blood group.
 Study Design: Cross-sectional study.
 Place and Duration of Study: Armed Forces Institute of Transfusion (AFIT) Rawalpindi, from Jan to Dec 2017.
 Methodology: The blood samples of pregnant women received for blood grouping, cross matching and antibodies screening were included in the study. The blood was typed for Rh-D along with ABO blood groups by Column Agglutination Technique (CAT), commonly known as the gel card method. Then, the samples included in the study wer
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Anasetti, C., P. Tan, J. A. Hansen, and P. J. Martin. "Induction of specific nonresponsiveness in unprimed human T cells by anti-CD3 antibody and alloantigen." Journal of Experimental Medicine 172, no. 6 (1990): 1691–700. http://dx.doi.org/10.1084/jem.172.6.1691.

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Fresh peripheral blood mononuclear cells exposed to alloantigen for 3-8 d in the presence of anti-CD3 antibodies showed no response after restimulation with cells from the original donor but remained capable of responding to third-party donors. Antigen-specific nonresponsiveness was induced by both nonmitogenic and mitogenic anti-CD3 antibodies but not by antibodies against CD2, CD4, CD5, CD8, CD18, or CD28. Nonresponsiveness induced by anti-CD3 antibody in mixed leukocyte culture was sustained for at least 34 d from initiation of the culture and 26 d after removal of the antibody. Anti-CD3 an
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Dissertations / Theses on the topic "Anti-D antibody"

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LE, LARD-KEIL ANDREA. "Etude de la structure primaire et secondaire d'un anticorps monoclonal humain anti-d." Paris 6, 1988. http://www.theses.fr/1988PA066358.

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Determination de la sequence en amino acide de l'anticorps monoclonal humain f5 dirige contre l'antigene d du systeme rhesus (rh). La sequence a permi une etude comparative avec d'autres anticorps de sequence deja connue. Une structure secondaire probable a pu etre etablie grace a des methodes de prediction de structure
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Campos, Marcela Vieira Xavier. "Correlação entre títulos de anticorpos anti-D e desfecho gestacional adverso em gestantes com antecedente de doença hemolítica perinatal." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-24032016-115636/.

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OBJETIVOS: Avaliar a correlação entre títulos de anticorpos anti-D em gestantes com antecedente de doença hemolítica perinatal (DHPN) e desfecho gestacional adverso. MÉTODOS: Coorte retrospectiva (2006-14) envolvendo gestantes Rh negativo, com antecedente de DHPN moderada ou grave, acompanhadas na Clínica Obstétrica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. Critérios de inclusão: gestação única com idade gestacional inferior a 32 semanas e ausência de derrames cavitários ou hidropisia fetal durante a 1a avaliação ultrassonográfica; e desfecho perinatal con
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Vogel, Stephanie [Verfasser]. "Analysis of Fc[gamma] receptor cross-linking and anti-CD4-specific monoclonal antibody function / Stephanie Vogel." Hannover : Technische Informationsbibliothek (TIB), 2016. http://d-nb.info/1122031939/34.

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Jurek, Betty [Verfasser]. "Effects of human anti-GluN1 antibodies on the offspring in a murine model of maternal antibody transfer / Betty Jurek." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2018. http://d-nb.info/1176631942/34.

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Jouni, Rabie [Verfasser]. "Anti-protamine/heparin antibodies : molecular and functional assessment of novel approaches to inhibit antibody-mediated platelet destruction / Rabie Jouni." Greifswald : Universitätsbibliothek Greifswald, 2016. http://d-nb.info/1109921470/34.

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GAITA, BARTOLOMEA. "Ricerca del sito di origine e del ruolo patogenetico degli anticorpi anti-transglutaminasi epidermica nella Dermatite Erpetiforme." Doctoral thesis, Università degli Studi di Trieste, 2022. http://hdl.handle.net/11368/3015191.

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La Dermatite Erpetiforme (DE) è una malattia infiammatoria cutanea caratterizzata da vescicole papulari pruriginose e da depositi granulari di IgA in corrispondenza delle papille dermiche o lungo la giunzione derma-epiderma. La malattia è considerata la manifestazione cutanea della celiachia, condividendo con quest’ultima l’origine autoimmune, la predisposizione genetica, la presenza di autoanticorpi IgA a livello sierico e la remissione clinica in seguito all’eliminazione del glutine dalla dieta. La transglutaminasi 3 o epidermica (TG-3 or eTG) rappresenta l’antigene verso cui si sviluppa la
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Haack, Stephanie [Verfasser], and Niklas [Gutachter] Beyersdorf. "A novel mouse model for systemic cytokine release upon treatment with a superagonistic anti-CD28 antibody / Stephanie Haack ; Gutachter: Niklas Beyersdorf." Würzburg : Universität Würzburg, 2021. http://d-nb.info/123439152X/34.

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Akhmetzyanova, Ilseyar [Verfasser], Ulf [Akademischer Betreuer] Dittmer, and Wiebke [Akademischer Betreuer] Hansen. "Regulation of the effective anti-tumor CD4+ T cell immunity by agonistic CD137 antibody / Ilseyar Akhmetzyanova. Gutachter: Wiebke Hansen. Betreuer: Ulf Dittmer." Duisburg, 2015. http://d-nb.info/1074102339/34.

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Hartung, Franziska [Verfasser], Walter [Akademischer Betreuer] Stühmer, Lutz [Akademischer Betreuer] Walter, Dieter [Akademischer Betreuer] Klopfenstein, and Matthias [Akademischer Betreuer] Dobbelstein. "Engineering of a bifunctional anti-Kv10.1 antibody for cancer therapy / Franziska Hartung. Gutachter: Lutz Walter ; Dieter Klopfenstein ; Matthias Dobbelstein. Betreuer: Walter Stühmer." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2011. http://d-nb.info/1042733465/34.

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Rieker, Marcel [Verfasser]. "Targeted Combination Therapy: Discovery and Evaluation of Synergistic Anticancer Effects of Anti-HER2-Duocarmycin Antibody-Drug Conjugates Combined with ATR Inhibitors / Marcel Rieker." Düren : Shaker, 2019. http://d-nb.info/1198600004/34.

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Books on the topic "Anti-D antibody"

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Wells, Elizabeth M. Anti-N-Methyl-D-Aspartate Receptor Encephalitis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0091.

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Anti- N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe but treatable recently identified form of immune-mediated encephalitis associated with antibodies in serum and cerebrospinal fluid (CSF) against the GluN1 subunit of the NMDAR. Research has rapidly expanded the understanding of disease mechanisms and how the condition manifests in different populations (e.g., pediatrics vs. adult, cancer vs. noncancer, male vs. female). Immunocytochemical, physiological, and molecular studies of the effects of human CSF on the rodent and murine brain in vitro and in vivo indicate a noncytotox
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Book chapters on the topic "Anti-D antibody"

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Khan, Ramsha, and Alan H. Lazarus. "Anti-D: A Type of IVIg." In Antibody Therapy. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-68038-5_5.

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Harter, Catherine, and Fergus Gracey. "Anti-N-methyl-D-aspartate receptor antibody encephalitis." In Rare Conditions, Diagnostic Challenges, and Controversies in Clinical Neuropsychology. Routledge, 2023. http://dx.doi.org/10.4324/9781003228226-10.

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Davis, J. M., C. M. Lavender, K. J. Bowes, J. A. J. Hanak, B. S. Combridge, and S. L. Kingsland. "Human Therapeutic Monoclonal Anti-D Antibody Produced in Long-Term Hollow-Fibre Culture." In Animal Cell Technology: Developments Towards the 21st Century. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0437-1_24.

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Matejtschuk, P., I. C. Sellick, E. Tarelli, S. F. Wheeler, and J. M. Davis. "Human Therapeutic Monoclonal Anti-D Antibody Produced in Long Term Hollow Fibre Culture." In Animal Cell Technology: Developments Towards the 21st Century. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0437-1_66.

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Baker, R. M., A. M. Brady, J. M. Davis, et al. "Human Therapeutic Monoclonal Anti-D Antibody Produced in Long-Term Hollow-Fibre Culture." In Animal Cell Technology: Developments Towards the 21st Century. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0437-1_83.

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Mirshahi, M., J. Soria, C. Soria, J. Y. Perrot, A. Bernadou, and C. Boucheix. "Fibrin(ogen) degradation products. Determination using a monoclonal anti D neo antibody. Advantages in clinical investigation." In Fibrin formation and Fibrinolysis, edited by D. A. Lane. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110871951-031.

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"Immunology & allergy." In Oxford Handbook of Clinical and Laboratory Investigation, edited by Drew Provan. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199233717.003.0004.

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Serum immunoglobulins 310 Immunoglobulin G subclasses 312 Evaluation of specific antibody production (anti-bacterial and anti-viral antibodies) 312 Immunoglobulin D 315 Electrophoresis &amp; immunofixation 315 Serum free light chains 317 ‘Bence Jones proteins’; urine electrophoresis and immunofixation 317 Cryoglobulins 317 β‎<sub>2</sub>-microglobulin 318 Acute phase proteins (C-reactive protein, erythrocyte sedimentation rate, serum amyloid A) ...
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McDonald, Jennifer, and Steven E. Miller. "Anti-NMDA Receptor Encephalitis." In Critical Care. Oxford University PressNew York, 2022. http://dx.doi.org/10.1093/med/9780190885939.003.0010.

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Abstract Initially recognized in young women with teratoma who presented with psychosis and/or memory problems, anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis can rapidly progress to severe neurologically mediated illness requiring intensive care. NMDAR encephalitis appears to have the most frequent incidence of paraneoplastic encephalitis. However, while most presentations of paraneoplastic encephalitis are poorly responsive to treatment, patients with antibody-mediated NMDAR encephalitis (first identified 2007) are more likely to respond to treatment. This chapter presents a case st
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Sardar, Nargis, Umer Bin Tariq, Sikandar Ali Khan, Muhammad Haris, and Arsalan Rasheed. "Vitamin D Detection Using Electrochemical Biosensors: A Comprehensive Overview." In New Advances in Biosensing [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.112212.

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Vitamin D plays a vital role in health; therefore, there is a need for a sensitive, selective, quick, and easy technique for its determination. Previous research has proposed electrochemical biosensors based on different carbon materials that are functionalized with various electrochemical biosensors. However, the existing problems and future opportunities for these sensors need further research. The practical use of electrochemical biosensors for vitamin D detection is attributed to their ability to detect vitamin D from diverse samples, including vitamin D production, in nature. This chapter
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Høilund-Carlsen, Poul F., Abass Alavi, and Jorge R. Barrio. "PET/CT/MRI in Clinical Trials of Alzheimer’s Disease." In Advances in Alzheimer’s Disease. IOS Press, 2024. https://doi.org/10.3233/aiad240044.

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With the advent of PET imaging in 1976, 2-deoxy-2-[18F]fluoro-D-glucose (FDG)-PET became the preferred method for in vivo investigation of cerebral processes, including regional hypometabolism in Alzheimer’s disease. With the emergence of amyloid-PET tracers, [11C]Pittsburgh Compound-B in 2004 and later [18F]florbetapir, [18F]florbetaben, and [18F]flumetamol, amyloid-PET has replaced FDG-PET in Alzheimer’s disease anti-amyloid clinical trial treatments to ensure “amyloid positivity” as an entry criterion, and to measure treatment-related decline in cerebral amyloid deposits. MRI has been used
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Conference papers on the topic "Anti-D antibody"

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Soria, J., C. Soria, Me Mirshahi, et al. "DDE COMPLEX DETERMINATION AS A SPECIFIC MARKER FOR FIBRINOLYSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643653.

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Monoclonal antibodies (McAb) reacting with fibrin degradation products (FbDP), but not with fibrinogen have been produced in order to determine specifically FbDP directly in plasma. Most of the McAb available however do also react with fragment D. Our anti D neo McAb reacts about 10 times less with fragment D than with FbDP but does not react with fibrinogen, fragment X or Y.In clinical investigation, even in pathological conditions in which there is a great release of tissue-type plasminogen activator (tpA), we have shown that fragment D is not generated in patients plasma. Therefore, the rea
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Lyu, W., Y. Zhou, Y. Zhuang, et al. "Surfactant Protein D Is Associated with 3-Month Mortality of Anti-MDA5 Antibody-Interstitial Lung Disease." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1093.

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Mueller-Eckhardt, C. "A SURVEY OF THE CLINICAL EFFICACY OF RETICULOENDOTHELIAL BLOCKADE EMPHASIZING INTRAVENOUS IgG AND ANTI-RH(D) GLOBULIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644760.

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"Blockade" of the RES is the maj0or therapeutic principle in autoimmune thrombocytopenic purpura (AITP) and related conditions. It can be accomplished by a number of possibilities which include, first, removal of the main sequestration site of antibody-sensitized platelets (i.e. splenectomy), or, second, functional "modulation" of the phagocytic capacity of the RES. The latter is achieved by either "unspecific" or "specific" means. "Unspecific" means are defined as being operative via a mechanism in which apparantly no immunological reactants are involved, while "specific" means comprise the d
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Picó, M., A. Ribera, C. Martin, J. Zuazu, and J. Monasterio. "GLANZMANN'S THROMBASTHENIA IN PREGNANCY: CLINICAL FEATURES AND PLATELET SEROLOGY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644556.

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A 24-year-old woman with a diagnosis of Glanzmann's Thrombasthenia (GT) type I (confirmed in our Hemostasis Section by sodium dodecyl sulphate-polyacrylamide gel electrophoresis) and with a history of several transfusions, was seen in our Service since the second month of her first pregnancy.In the first visit a strong anti-Rh(D) antibody was found in her serum. In 28th week an ammiocentesis was done. Seventy two hours later, she was hospitalized because of disminution of foetal movements. Then, a platelet-allo-antibody, IgG+IgM type (title IgG 1/512, IgM 1/2) was detected in her scrum by immu
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Nery, Julia Pio Fernandes, Kaisy Nagella Alves, Victor Teatini Ribeiro, and Antônio Pereira Gomes. "Anti-N-Methyl D-Aspartate (NMDA) receptor encephalitis after herpes virus meningoencephalitis: a case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.681.

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Anti-N-methyl D-aspartate (NMDA) receptor encephalitis is an autoimmune disease of the central nervous system characterized by psychiatric and neurological symptoms. This pathology may be associated with paraneoplastic syndrome and viral infections, especially the Herpes simplex virus. However, a considerable number of cases may remain without an identifiable triggering factor. We report the case of a 17-year-old girl who presented with headache, fever and meningeal signs. Cerebrospinal fluid (CSF) analysis showed a herpes virus infection. After treatment using Acyclovir for 21 days, the patie
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Nishino, N., Y. Tokura, S. Sakaguchi, S. Takahashi, Y. Takada, and A. Takada. "URINARY TRYPSIN INHIBITOR RELATED SUBSTANCE (UTIR) IN THE PLASMA AND TISSUES OF STOMACH CANCER." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643193.

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Urinary trypsin inhibitor(UTI) is a single chain glycoprotein with molecular weight of 67,000. In SDS-PAGE a hand appeared at molecular weight of 48,000. Results of gel filtration indicate its molecular weight of 67,000, suggesting extensive changes in its conformation in SDS. Injection of UTI into rabbit did not result in the formation of anti-UTI antibody. Conjugation of rabbit serum albumin with UTI gave rise to antibody formation upon injection into rabbits. Anti-UTI did not cross-react with anti-inter(Xtrypsin inhibitor. A highly sensitive enzyme immunoassay of UTI was developed using β-D
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KUROSO, K., S. IKEMATSU, M. HADA, M. FUJIMAKI, and K. FUKUTAKE. "DEVELOPMENT OF A NEW ASSAY METHOD FOR THE DETECTION OF DD/E COMPLEX." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643130.

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A new assay method for the detection of DD/E complex derived from crosslinked fibrin is developed. This assay is performed on a microtitre plate using capture/tag antibody technique, in which the monoclonal antibody against D dimer fragment (DD-3B6, MAbCO) is coated and anti-E fragment polyclonal F(ab)’2 conjugated with horse radish peroxidase is for a tag-anti body. Antigen dilution curve is drawn in the range of 0.01-1.0 pg/ml of purified DD/E complex. DD/E complex can be measured specifically and other high molecular weight derivatives from crosslinked fibrin show a little crossreaction, th
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Seifried, E., and P. Tanswell. "IN VITRO EFFECTS OF RECOMBINANT TISSUE TYPE PLASMINOGEN ACTIVATOR ON FIBRINOLYTIC AND COAGULATION PARAMETERS AND ITS PREVENTION BY SPECIFIC ANTIBODY, D-PHE-PRO-ARG-CTUCl AND APROTININ." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643119.

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Monitoring of systemic effects during rt-PA therapy has shown of depletion of fibrinogen-antiplasmin, plasminogen and other hemostatic factors. Because in vitro activation of plasminogen may occur between blood collection and freezing and thawing before assaying we analysed the influence of 0,0.2, 2.0 and 10.0,ug rt-PA/ml citrate blood (final conc.) on hemostatic and fibrinolytic parameters and its inhibition by 3 different inhibitors. Addition of rt-PA to citrated whole blood without an inhibitor induced a concentration-dependent depletion of Fbg, Plgα2-Apl,α2-M, C1 - I, α2-Atrp, a loss of ac
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Bussel, J. "FOR MODULATION AS A MEANS OF ELEVATING THE PLATELET COUNT IN ITP." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644761.

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ITP is an autoantibody-mediated disease which would logically be treated by decreasing the level of autoantibody. However, the most exciting developments in understanding the pathophysiology of the thrombocytopenia and its treatment involve a better understanding of the MPS FcR system and ways in which it can be modulated. This work has focussed on phagocytic paralysis or FcR blockade (FcRBl): the slowing of destruction of antibody-coated platelets despite the persistent presence of antibody on the surface of the platelet.Several areas have been explored in learning about the MPS system. Inves
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Smith, R., Z. Liu, K. Laskey, et al. "P115 Vitamin D concentrations are not associated with anti-SARS-CoV-2 antibody responses following mRNA COVID-19 vaccine in IBD patients treated with infliximab." In BSG LIVE’23, 19–22 June, ACC Liverpool. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2023. http://dx.doi.org/10.1136/gutjnl-2023-bsg.187.

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Reports on the topic "Anti-D antibody"

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Splitter, Gary, and Menachem Banai. Attenuated Brucella melitensis Rough Rev1 Vaccine. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7585199.bard.

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Abstract:
The original objectives of the proposal were: 1. Compare mutants 444 and 710 to Rev1 (parent strain), and 16M (field strain) in murine and human macrophage lines for phenotypic differences. 2. Determine in vivo virulence and survival of the mutants 444 and 710 in guinea pigs and mice. 3. Determine humoral and cell-mediated immune responses induced by mutants 444 and 710 in guinea pigs and mice. 4. Determine in vivo protection of mice and guinea pigs provided by mutants 444 and 710 compared to Rev1. Background: While human and animal brucellosis are rare in the U.S., brucellosis caused by B. me
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