Log in

Relevant bibliographies by topics / Anti-D antibody / Journal articles

To see the other types of publications on this topic, follow the link: Anti-D antibody.

Journal articles on the topic 'Anti-D antibody'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Anti-D antibody.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Merron, B. M., K. Maguire, and K. Morris. "When is an anti-D antibody not an anti-D antibody?" Transfusion Medicine 25, no. 2 (2015): 115–17. http://dx.doi.org/10.1111/tme.12200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Bachegowda, Lohith S., Yan H. Cheng, Thomas Long, and Beth H. Shaz. "Impact of Uniform Methods on Interlaboratory Antibody Titration Variability: Antibody Titration and Uniform Methods." Archives of Pathology & Laboratory Medicine 141, no. 1 (2016): 131–38. http://dx.doi.org/10.5858/arpa.2015-0351-oa.

Full text

Abstract:

Context.—Substantial variability between different antibody titration methods prompted development and introduction of uniform methods in 2008. Objective.—To determine whether uniform methods consistently decrease interlaboratory variation in proficiency testing. Design.—Proficiency testing data for antibody titration between 2009 and 2013 were obtained from the College of American Pathologists. Each laboratory was supplied plasma and red cells to determine anti-A and anti-D antibody titers by their standard method: gel or tube by uniform or other methods at different testing phases (immediate

APA, Harvard, Vancouver, ISO, and other styles

3

Vildanova, N. S., E. S. Kormshchikova, E. N. Kalinina, K. A. Vorobiev, I. V. Paramonov, and E. Yu Kudasheva. "Human anti-D immunoglobulin preparations: potency standardisation milestones." Biological Products. Prevention, Diagnosis, Treatment 22, no. 3 (2022): 241–48. http://dx.doi.org/10.30895/2221-996x-2022-22-3-241-248.

Full text

Abstract:

Human anti-D immunoglobulin preparations derived from human immune plasma are much needed and highly effective for specific anti-D prevention of perinatal complications and treatment of primary immune thrombocytopenia. The effectiveness of immune suppression is a direct function of the active ingredient dose received with the medicinal product. To improve the accuracy of anti-D antibody quantification, it is recommended to use certified reference materials with values assigned in international units (IUs). The aim of this study was to analyse the main stages in the development of the internati

APA, Harvard, Vancouver, ISO, and other styles

4

Muller, Corinna L., Jodi L. Schucker, and Fouad N. Boctor. "When anti-G and anti-C antibodies masquerade as anti-D antibody." Journal of Maternal-Fetal & Neonatal Medicine 24, no. 1 (2010): 193–94. http://dx.doi.org/10.3109/14767058.2010.482616.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Brinc, Davor, and Alan H. Lazarus. "Mechanisms of anti-D action in the prevention of hemolytic disease of the fetus and newborn." Hematology 2009, no. 1 (2009): 185–91. http://dx.doi.org/10.1182/asheducation-2009.1.185.

Full text

Abstract:

Abstract Anti-D is routinely and effectively used to prevent hemolytic disease of the fetus and newborn (HDFN) caused by the antibody response to the D antigen on fetal RBCs. Anti-D is a polyclonal IgG product purified from the plasma of D-alloimmunized individuals. The mechanism of anti-D has not been fully elucidated. Antigenic epitopes are not fully masked by anti-D and are available for immune system recognition. However, a correlation has frequently been observed between anti-D-mediated RBC clearance and prevention of the antibody response, suggesting that anti-D may be able to destroy RB

APA, Harvard, Vancouver, ISO, and other styles

6

Mathiesen, Line, Leif K. Nielsen, Jan Terje Andersen, et al. "Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions." Blood 122, no. 7 (2013): 1174–81. http://dx.doi.org/10.1182/blood-2012-12-473843.

Full text

Abstract:

Key Points Retained FcRn binding of an IgG3 antibody devoid of FcgR and C1q binding, cellular cytotoxicity and complement activation. Inhibition of pathogenic polyclonal anti-D in antibody-dependent cellular toxicity by a hinge region deleted anti-D IgG3 antibody with efficient transplacental transport capacity.

APA, Harvard, Vancouver, ISO, and other styles

7

Sinha, Ayesha, Najla Haneefa Basheela, Durba Biswas, Debapriya Basu, and Suvro Sankha Datta. "A Rare Case of Pregnancy-induced Anti-D, Anti-C, and Anti-G Antibodies." Global Journal of Transfusion Medicine 9, no. 1 (2024): 70–72. http://dx.doi.org/10.4103/gjtm.gjtm_62_23.

Full text

Abstract:

ABSTRACT A 39-year-old female with breast carcinoma presented with complaints of menorrhagia and weakness. At current admission, her hemoglobin was 6.2 g/dL, and a requisition for packed red blood cells (PRBCs) was sent to the blood center. There was no previous history of transfusions, and the last pregnancy was 11 years ago. During the immunohematological (IH) workup, she was typed as O, ccdee, with an extra reaction in reverse grouping. Her antibody screening was positive, followed by the antibody identification, which was suggestive of anti-D and anti-C antibodies. The “Rhesus G” is an imm

APA, Harvard, Vancouver, ISO, and other styles

8

Hensley, Jennifer G., Katherine P. Coughlin, and Laura L. Klein. "A Curious Case of Anti‐D Antibody Titer." Journal of Midwifery & Women's Health 54, no. 6 (2009): 497–502. http://dx.doi.org/10.1016/j.jmwh.2009.08.006.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Bajwa, Hussan, Maqbool Alam, Muhammad Ali Rathore, and Muhammad Sajid Yazdani. "Rh Alloantibodies in Rh D Negative Blood Group Pregnant Women - A Regional Transfusion Centre Study." Pakistan Armed Forces Medical Journal 72, no. 3 (2022): 939–42. http://dx.doi.org/10.51253/pafmj.v72i3.5124.

Full text

Abstract:

Objective: To determine the frequency of Rh alloantibodies in pregnant women of the Rh-D negative blood group. Study Design: Cross-sectional study. Place and Duration of Study: Armed Forces Institute of Transfusion (AFIT) Rawalpindi, from Jan to Dec 2017. Methodology: The blood samples of pregnant women received for blood grouping, cross matching and antibodies screening were included in the study. The blood was typed for Rh-D along with ABO blood groups by Column Agglutination Technique (CAT), commonly known as the gel card method. Then, the samples included in the study wer

APA, Harvard, Vancouver, ISO, and other styles

10

Anasetti, C., P. Tan, J. A. Hansen, and P. J. Martin. "Induction of specific nonresponsiveness in unprimed human T cells by anti-CD3 antibody and alloantigen." Journal of Experimental Medicine 172, no. 6 (1990): 1691–700. http://dx.doi.org/10.1084/jem.172.6.1691.

Full text

Abstract:

Fresh peripheral blood mononuclear cells exposed to alloantigen for 3-8 d in the presence of anti-CD3 antibodies showed no response after restimulation with cells from the original donor but remained capable of responding to third-party donors. Antigen-specific nonresponsiveness was induced by both nonmitogenic and mitogenic anti-CD3 antibodies but not by antibodies against CD2, CD4, CD5, CD8, CD18, or CD28. Nonresponsiveness induced by anti-CD3 antibody in mixed leukocyte culture was sustained for at least 34 d from initiation of the culture and 26 d after removal of the antibody. Anti-CD3 an

APA, Harvard, Vancouver, ISO, and other styles

11

Sharma, Geetika, Sangeeta Pahuja, Deeksha Singh, Ramvilash ., and Manisha . "Non RhD isoimmunization causing severe hemolytic disease of fetus and newborn in Rh positive pregnancies: report of 2 cases with review of literature." International Journal of Contemporary Pediatrics 7, no. 4 (2020): 955. http://dx.doi.org/10.18203/2349-3291.ijcp20201159.

Full text

Abstract:

Anti D immunoprophylaxis widespread use in antenatal patients has led to dramatic reduction in the rates of alloimmunization due to anti D, which is the most common Rh antibody causing severe Hemolytic Disease of Fetus and New born (HDFN). However, there has been increase in the rates of non Rh D antibodies causing alloimmunization in pregnant women and leading to moderate to severe HDFN. We hereby report two cases of neonates presenting with moderate to severe HDFN with strongly positive DAT due to Rh anti-c antibody in Rh-positive mothers. Thus, antenatal antibody screening should be done in

APA, Harvard, Vancouver, ISO, and other styles

12

Moiz, Bushra, Muhammad Hasan, Muhammad Salman, Bhawna Kumari, Emily Black, and Yew-Wah Liew. "Anti-LW masquerading as anti-D in a D+ patient." Immunohematology 41, no. 1 (2025): 11–16. https://doi.org/10.2478/immunohematology-2025-0004.

Full text

Abstract:

Abstract LWa, LWab, LWb, and LWEM are the four main antigens of the Landsteiner–Weiner (LW) blood group system. LW expression may be weakened during pregnancy and immune dysregulation, with the subsequent appearance of anti-LW. Here, we describe a case of an elderly male patient in whom transfusion of red blood cells (RBCs) became challenging because of the presence of anti-LW. A 61-year-old male patient presented with shortness of breath and a hemoglobin level of 7.0 g/dL, requiring RBC transfusions. Serologic workup of his blood sample showed his RBCs to be group A, D+, but his serum was inc

APA, Harvard, Vancouver, ISO, and other styles

13

Thakkar, Garima H., Nidhi M. Bhatnagar, Sangita D. Shah, and Mamta C. Shah. "Severe haemolytic disease of newborn with possibility of blocked D phenomenon:A Case Report." June 2024 16, no. 01 (2024): 70–72. http://dx.doi.org/10.56018/bjkines20240612.

Full text

Abstract:

Anti-D is the most common antibody causing severe hemolytic disease of foetus and newborn (HDFN).The mothers who have very high titres of anti-D,antibodies can coat and block D antigens on red blood cells (RBCs) of the newborn.This blocking phenomenon prevents the agglutination of RBCs with IgM type of anti-D antisera.This results in false negative results.Here, we report the case of 1 day old baby born to a multiparous female with Rh Negative blood group suffering from severe HDFN.Mother and baby’s samples were sent to our blood centre for the advanced immunohaematological analysis.On detaile

APA, Harvard, Vancouver, ISO, and other styles

14

Shereen Umer, Hareem Noor, Hassan Raza, Iqra Rasool, Tayyab Noor, and Aiyesha Imran. "Occurrence of anti D alloantibodies among weak D and D negative patients." Professional Medical Journal 30, no. 04 (2023): 535–40. http://dx.doi.org/10.29309/tpmj/2023.30.04.7380.

Full text

Abstract:

Objective: To estimate the frequency of anti-D alloantibodies in patients with weak or negative D. Study Design: Cross-sectional study. Setting: Under CIP/IRB/1111 in the Blood Bank of CHUGHTAI Institute of Pathology. Period: May 2022 to October 2022. Material & Methods: Patients who booked their blood group testing at this laboratory were tested for their ABO RH blood type. The EDTA and yellow top serum samples were taken from patients. Blood group was identified using tube method. Patients with Rh-D negative blood type and weak D were included in this study. Those patients were screened

APA, Harvard, Vancouver, ISO, and other styles

15

Khadem, G. M., S. Heble, R. Kumar, and C. White. "Anti-N-methyl-d-aspartate receptor antibody limbic encephalitis." Internal Medicine Journal 39, no. 1 (2009): 54–56. http://dx.doi.org/10.1111/j.1445-5994.2008.01808.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Tamrakar, Basant Kumar, D. Karki, and A. Nagila. "Decreased Level of Vitamin D is Associated with Rheumatoid Arthritis Patients from Western Region of Nepal." Journal of Gandaki Medical College-Nepal 11, no. 02 (2018): 46–50. http://dx.doi.org/10.3126/jgmcn.v11i02.22963.

Full text

Abstract:

Background: Rheumatoid Arthritis (RA) is a progressive, chronic type of autoimmune disease and the role of vitamin D in the pathogenesis of RA is under investigation. Objective: The objective of this study was to determine the vitamin D deficiency in patients with RA as compared to healthy controls and to assess the relationship between serum vitamin D and anti-cyclic citrullinated peptide (anti-CCP) antibody levels in patients with newly diagnosed rheumatoid arthritis. Methods: The study was conducted between January 2017 to February 2018 at Fishtail Hospital and Research centre.

APA, Harvard, Vancouver, ISO, and other styles

17

Abu Fanne, Rami, Mahmud Moed, Aviv Kedem, et al. "SARS-CoV-2 Infection-Blocking Immunity Post Natural Infection: The Role of Vitamin D." Vaccines 11, no. 2 (2023): 475. http://dx.doi.org/10.3390/vaccines11020475.

Full text

Abstract:

Objective and Aim: The extent of the protection against SARS-CoV-2 conferred by natural infection is unclear. Vitamin D may have a role in the interplay between SARS-CoV-2 infection and the evolving acquired immunity against it. We tested the correlation between baseline 25(OH) D content and both the reinfection rate and the anti-spike protein antibody titer following COVID-19 infection. Methods A retrospective observational survey that included a large convalescent COVID-19 population of subjects insured by the Leumit HMO was recorded between 1 February 2020 and 30 January 2022. Inclusion cri

APA, Harvard, Vancouver, ISO, and other styles

18

Mahmoud, Tamer, Harry Schroeder та John Kearney. "Limiting HCDR3 diversity abrogates the antibody response to the bacterial polysaccharide α 1→3 Dextran (45.20)". Journal of Immunology 186, № 1_Supplement (2011): 45.20. http://dx.doi.org/10.4049/jimmunol.186.supp.45.20.

Full text

Abstract:

Abstract Anti-polysaccharide antibody responses in mice are often oligoclonal and the mechanisms involved in the production and subsequent antigen-driven selection of these clones are poorly understood. In this study, we investigated the α 1→3 Dextran (DEX) antibody response of gene-targeted mice limited to the usage of one DH gene segment (D-limited mice). We show that the DEX-specific antibody response is broadly comparable in D-limited mice to that of wild type BALB/c (WT) mice. D-limited mice forced to use DH reading frame 2 (ΔD-DµFS) showed both a higher total anti-DEX antibody response c

APA, Harvard, Vancouver, ISO, and other styles

19

Feller, John M., Ann M. Simpson, Margaret Nelson, et al. "Growth-Promoting Effect of Rh(D) Antibody on Human Pancreatic Islet Cells." Journal of Clinical Endocrinology & Metabolism 93, no. 9 (2008): 3560–67. http://dx.doi.org/10.1210/jc.2008-0510.

Full text

Abstract:

Context/Objective: Hyperinsulinism with islet cell hyperplasia is a frequent complication, of unknown cause, in hemolytic disease of the newborn, occurring in Rh(D)-positive infants of Rh-isoimmunized Rh(D)-negative mothers, but not in infants with other hemolytic disorders. We investigated the possibility that trans-placentally acquired anti-D Ig is the cause of both conditions. Design: Monolayer cultures of human islet cells were exposed to sera from Rh-isoimmunized mothers and newborns, where jaundice, hyperinsulinism, and hypoglycemia in the infant had ensued. Parallel cultures with anti-D

APA, Harvard, Vancouver, ISO, and other styles

20

Tian, Ming, Hwei-Ling Cheng, Michael T. Kimble, et al. "An in vivo method for diversifying the functions of therapeutic antibodies." Proceedings of the National Academy of Sciences 118, no. 10 (2021): e2025596118. http://dx.doi.org/10.1073/pnas.2025596118.

Full text

Abstract:

V(D)J recombination generates mature B cells that express huge repertoires of primary antibodies as diverse immunoglobulin (Ig) heavy chain (IgH) and light chain (IgL) of their B cell antigen receptors (BCRs). Cognate antigen binding to BCR variable region domains activates B cells into the germinal center (GC) reaction in which somatic hypermutation (SHM) modifies primary variable region-encoding sequences, with subsequent selection for mutations that improve antigen-binding affinity, ultimately leading to antibody affinity maturation. Based on these principles, we developed a humanized mouse

APA, Harvard, Vancouver, ISO, and other styles

21

Chahardoli, Reza, Ali-Akbar Saboor-Yaraghi, Atieh Amouzegar, Davood Khalili, Azita Vakili, and Fereidoun Azizi. "Can Supplementation with Vitamin D Modify Thyroid Autoantibodies (Anti-TPO Ab, Anti-Tg Ab) and Thyroid Profile (T3, T4, TSH) in Hashimoto’s Thyroiditis? A Double Blind, Randomized Clinical Trial." Hormone and Metabolic Research 51, no. 05 (2019): 296–301. http://dx.doi.org/10.1055/a-0856-1044.

Full text

Abstract:

AbstractHashimoto’s thyroiditis (HT) is the most prevalent autoimmune disorder characterized by the destruction of thyroid cells caused by leukocytes and antibody-mediated immune processes accompanied by hypothyroidism. In recent years, evidence has emerged pointing to various roles for vitamin D, including, proliferation and differentiation of normal and cancer cells, cardiovascular function, and immunomodulation. Vitamin D deficiency has been especially demonstrated in HT patients. The aim of this study was to investigate the effect of vitamin D on circulating thyroid autoantibodies and thyr

APA, Harvard, Vancouver, ISO, and other styles

22

Lomas-Francis, Christine, Rosyln Yomtovian, Claire McGrath, Phyllis S. Walker, and Marion E. Reid. "A confusion in antibody identification:anti-D production after anti-hrB." Immunohematology 23, no. 4 (2020): 158–60. http://dx.doi.org/10.21307/immunohematology-2019-334.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Gualtierotti, Roberta, Alessio Di Giacomo, Elena Raschi, Maria Orietta Borghi, and Pier Luigi Meroni. "Vitamin D and Anti-Phospholipid Antibody Syndrome: A Comprehensive Review." Open Rheumatology Journal 12, Suppl-1, M5 (2018): 248–60. http://dx.doi.org/10.2174/1874312901812010248.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Dugoujon, J. Michel, Gerda G. de Lange, Antoine Blancher, Simone Alie-Daram, and Yvonne Marty. "Characterization of an IgG2, G2m(23) Anti-Rh-D Antibody." Vox Sanguinis 57, no. 2 (1989): 133–36. http://dx.doi.org/10.1159/000461021.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Percival, D. A., A. D. Shuttleworth, E. D. Williamson, and D. C. Kelly. "Anti-idiotypic antibody-induced protection against Clostridium perfringens type D." Infection and Immunity 58, no. 8 (1990): 2487–92. http://dx.doi.org/10.1128/iai.58.8.2487-2492.1990.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Dugoujon, J. Michel, Gerda G. Lange, Antoine Blancher, Simone Alie-Daram, and Yvonne Marty. "Characterization of an IgG2, G2m(23) Anti-Rh-D Antibody." Vox Sanguinis 57, no. 2 (1989): 133–36. http://dx.doi.org/10.1111/j.1423-0410.1989.tb01150.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Kharkevich, Ol'ga N., and Elena N. Dorovskaya. "The effectiveness of the organization and specific prevention of Rh-conflict during pregnancy." Russian Military Medical Academy Reports 42, no. 2 (2023): 141–47. http://dx.doi.org/10.17816/rmmar312193.

Full text

Abstract:

AIM: The aim of the study was to evaluate the effectiveness of the organization and medical provision of complex specific antenatal and postpartum prevention of primary isoimmunization with domestic anti-Rh0(D) immunoglobulin in Rh-negative women. MATERIALS AND METHODS: To achieve the goal, an algorithm for managing pregnancy in Rh-negative women was developed, complex antenatal and postpartum prophylaxis of primary isoimmunization with anti-Rh0(D) immunoglobulin was carried out, and its effectiveness was evaluated in 37 women who gave birth to Rh-positive newborns. If antibodies to the

APA, Harvard, Vancouver, ISO, and other styles

28

Chilver-Stainer, Lara, Bernhard Lämmle, and Lorenzo Alberio. "Titre of anti-heparin/PF4-antibodies and extent of in vivo activation of the coagulation and fibrinolytic systems." Thrombosis and Haemostasis 91, no. 02 (2004): 276–82. http://dx.doi.org/10.1160/th03-07-0454.

Full text

Abstract:

SummaryHeparin-induced thrombocytopenia (HIT) is mediated by antibodies directed against the heparin/platelet factor 4 (PF4) complex. Our aim was to investigate whether the antibody titre is associated with the degree of in vivo thrombin generation. We measured the anti-heparin/PF4-antibody titre, prothrombin fragments F1+2, thrombin-antithrombin (TAT) complexes and D-dimers in plasma samples from 225 patients with suspected HIT. Antibody titres as detected by a particle gel immunoassay strongly correlated with optical density values measured by ELISA (r=0.84, p<0.0001). Patients with titre

APA, Harvard, Vancouver, ISO, and other styles

29

Iberahim, Salfarina, Maryam Jameelah Aizuddin, Nurulhuda Abd Kadir, et al. "Hemolytic Disease of Fetus and Newborn in a Primigravida with Multiple Alloantibodies Involving Anti-Jka and Anti-E: A Case Report." Oman Medical Journal 35, no. 6 (2020): e206-e206. http://dx.doi.org/10.5001/omj.2020.135.

Full text

Abstract:

The majority of hemolytic disease of the fetus and newborn (HDFN) reported in the literature is due to ABO and rhesus incompatibility. However, there are also other minor blood groups that have been identified as a cause of HDFN, although the occurrence is much rarer. The antibody screening program for D negative mother and the anti-D immunoglobulin treatment showed a significant reduction of the occurrence of HDFN secondary to anti-D. In a developed country, the screening for red blood cell antibody in the pregnant mother other than anti-D reduced the possibility of HDFN occurrence hence redu

APA, Harvard, Vancouver, ISO, and other styles

30

Rolf, Linda, Anne-Hilde Muris, Amandine Mathias, et al. "Exploring the effect of vitamin D3 supplementation on the anti-EBV antibody response in relapsing-remitting multiple sclerosis." Multiple Sclerosis Journal 24, no. 10 (2017): 1280–87. http://dx.doi.org/10.1177/1352458517722646.

Full text

Abstract:

Background: Epstein–Barr virus (EBV) infection and vitamin D insufficiency are potentially interacting risk factors for multiple sclerosis (MS). Objectives: To investigate the effect of high-dose vitamin D3 supplements on antibody levels against the EBV nuclear antigen-1 (EBNA-1) in patients with relapsing-remitting multiple sclerosis (RRMS) and to explore any underlying mechanism affecting anti-EBNA-1 antibody levels. Methods: This study utilized blood samples from a randomized controlled trial in RRMS patients receiving either vitamin D3 (14,000 IU/day; n = 30) or placebo ( n = 23) over 48 w

APA, Harvard, Vancouver, ISO, and other styles

31

Negi, Gita, and Gaur Dushyant Singh. "Anti Rh Hemolytic Disease due to Anti C Antibody: Is Testing for Anti D Antibodies Enough?" Indian Journal of Hematology and Blood Transfusion 28, no. 2 (2011): 121–22. http://dx.doi.org/10.1007/s12288-011-0105-z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Das, Soumya, Shamee Shastry, and Poornima B. Baliga. "Severe haemolytic disease of a newborn with variant D mimicking blocked-D phenomenon." BMJ Case Reports 12, no. 12 (2019): e231891. http://dx.doi.org/10.1136/bcr-2019-231891.

Full text

Abstract:

Anti-D is still the most common antibody causing severe haemolytic disease of the fetus and newborn (HDFN). In a mother with a very high titer of anti-D, antibodies can coat and block the D antigens on the red blood cells of the newborn. This blocking phenomenon prevents agglutination of the D-positive red cells with the IgM anti-D typing reagent, giving false negative results. Here, we report the case of a newborn with variant D phenotype and severe HDFN, which mimicked the blocked-D phenomenon, which, at the first instance, confused both the treating clinicians and the transfusion service pe

APA, Harvard, Vancouver, ISO, and other styles

33

Hows, J., K. Beddow, E. Gordon-Smith, et al. "Donor-derived red blood cell antibodies and immune hemolysis after allogeneic bone marrow transplantation." Blood 67, no. 1 (1986): 177–81. http://dx.doi.org/10.1182/blood.v67.1.177.177.

Full text

Abstract:

Abstract Six cases of immune hemolytic anemia attributed to donor-derived red cell antibodies after allogeneic bone marrow transplantation (BMT) are reported. In 2/6 cases, severe intravascular hemolysis was seen, 6/6 required increased red cell transfusion, and 1/6 was treated by plasma exchange. All recipients were receiving cyclosporine to prevent graft-v- host disease. Investigations showed that in each case, the donor lacked ABO or Rho(D) red cell antigens present in the recipient. The direct antiglobulin test was positive in 6/6. Relevant serum antibody (anti-A, four cases; anti-B, one c

APA, Harvard, Vancouver, ISO, and other styles

34

Hows, J., K. Beddow, E. Gordon-Smith, et al. "Donor-derived red blood cell antibodies and immune hemolysis after allogeneic bone marrow transplantation." Blood 67, no. 1 (1986): 177–81. http://dx.doi.org/10.1182/blood.v67.1.177.bloodjournal671177.

Full text

Abstract:

Six cases of immune hemolytic anemia attributed to donor-derived red cell antibodies after allogeneic bone marrow transplantation (BMT) are reported. In 2/6 cases, severe intravascular hemolysis was seen, 6/6 required increased red cell transfusion, and 1/6 was treated by plasma exchange. All recipients were receiving cyclosporine to prevent graft-v- host disease. Investigations showed that in each case, the donor lacked ABO or Rho(D) red cell antigens present in the recipient. The direct antiglobulin test was positive in 6/6. Relevant serum antibody (anti-A, four cases; anti-B, one case; anti

APA, Harvard, Vancouver, ISO, and other styles

35

Allhorn, Maria, Juana G. Briceño, Lucie Baudino, et al. "The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis." Blood 115, no. 24 (2010): 5080–88. http://dx.doi.org/10.1182/blood-2009-08-239020.

Full text

Abstract:

Abstract EndoS from Streptococcus pyogenes is an immunomodulating enzyme that specifically hydrolyzes glycans from human immunoglobulin G and thereby affects antibody effector functions. Autoimmune hemolytic anemia is caused by antibody-mediated red blood cell (RBC) destruction and often resists treatment with corticosteroids that also cause frequent adverse effects. We show here that anti-RhD (anti-D) and rabbit anti–human-RBC antibodies (anti-RBC) mediated destruction of RBC, ie, phagocytosis, complement activation, and hemolysis in vitro and in vivo was inhibited by EndoS. Phagocytosis by m

APA, Harvard, Vancouver, ISO, and other styles

36

Semple, John W., Rukhsana Aslam, Michael Kim, et al. "The Specificity and Isotype of Monoclonal Anti-D Antibodies Dictates Their Ability To Inhibit Opsonized Platelet Phagocytosis." Blood 108, no. 11 (2006): 21. http://dx.doi.org/10.1182/blood.v108.11.21.21.

Full text

Abstract:

Abstract The use of polyclonal anti-D is the established treatment for prophylaxis against rhesus immunization in Rh(D) negative pregnant women and is effective in raising the platelet counts in patients with autoimmune thrombocytopenic purpura (AITP). Since the supply of plasma derived anti-D antibodies is limited and plasma products carry the risk of infectious complications, replacement with monoclonal anti-D antibodies is a promising alternative. This study analyzed the efficacy of polyclonal anti-D (WinRho®SDF, Cangene) and six human monoclonal anti-D antibodies with differeing isotypes a

APA, Harvard, Vancouver, ISO, and other styles

37

Aburto, A., D. Zapata, E. Retamales, H. Moscoso, C. Canales, and C. Escobar. "Erythrocyte antigens and antibodies in the Chilean population." Immunohematology 37, no. 4 (2021): 151–56. http://dx.doi.org/10.21307/immunohematology-2021-024.

Full text

Abstract:

Abstract Chile does not have a national registry of immunohematologic test results; there are no data on the prevalence of erythrocyte antigens and the frequency of antibodies in this population. Therefore, foreign references are used for decision-making. In this study, a standard questionnaire was used in 74 laboratories of public and private establishments. The information from tests conducted in 2015 was requested: ABO and D typing, antibody detection, antibody identification, and erythrocyte phenotype. Prevalence for the ABO-D phenotypes were obtained at the country level (D+ [94.4%] and D

APA, Harvard, Vancouver, ISO, and other styles

38

Casadevall, A., and M. D. Scharff. "The mouse antibody response to infection with Cryptococcus neoformans: VH and VL usage in polysaccharide binding antibodies." Journal of Experimental Medicine 174, no. 1 (1991): 151–60. http://dx.doi.org/10.1084/jem.174.1.151.

Full text

Abstract:

Cryptococcus neoformans is a ubiquitous fungus that can cause serious infections in humans. The fungus has a polysaccharide (C. neoformans capsular polysaccharide; CNPS) capsule that contributes to its pathogenicity and can elicit an antibody response. Nevertheless, only 4 of 60 BALB/c mice chronically infected with C. neoformans had a detectable increase in serum anti-CNPS. The sera of three responder mice contained both IgM and IgG anti-CNPS antibody, and the titers of lambda and kappa anti-CNPS antibody were approximately equal. Eight IgM and one IgG3 monoclonal antibodies (mAbs) were gener

APA, Harvard, Vancouver, ISO, and other styles

39

Sun, S., and K. Sugane. "Immunodiagnosis of human dirofilariasis by enzyme-linked immunosorbent assay using recombinant DNA-derived fusion protein." Journal of Helminthology 66, no. 3 (1992): 220–26. http://dx.doi.org/10.1017/s0022149x00014590.

Full text

Abstract:

ABSTRACTAn enzyme-linked immunosorbent assay (ELISA) using antigenic β-galactosidase-Dirofilaria immitis recombinant fusion protein (FP) obtained by the recombinant DNA technique provided a useful diagnostic tool for human dirofilariasis. D. immitis-infected human sera reacted strongly with FP that was immobilized with anti-β-galactosidase monoclonal antibody on microplates. However, the FP did not react with sera from patients with other filariasis. In detection of anti-D. immitis IgG antibody. ELISA using FP was highly sensitive and specific compared to that using crude somatic antigen.

APA, Harvard, Vancouver, ISO, and other styles

40

Chang, Tylis Y., and Don L. Siegel. "Genetic and Immunological Properties of Phage-Displayed Human Anti-Rh(D) Antibodies: Implications for Rh(D) Epitope Topology." Blood 91, no. 8 (1998): 3066–78. http://dx.doi.org/10.1182/blood.v91.8.3066.3066_3066_3078.

Full text

Abstract:

Understanding anti-Rh(D) antibodies on a molecular level would facilitate the genetic analysis of the human immune response to Rh(D), lead to the design of therapeutically useful reagents that modulate antibody binding, and provide relevant information regarding the structural organization of Rh(D) epitopes. Previously, we described a Fab/phage display-based method for producing a large array of anti-Rh(D) antibodies from the peripheral blood lymphocytes of a single alloimmunized donor. In the current study, we present a detailed analysis of 83 randomly selected clones. Sequence analysis showe

APA, Harvard, Vancouver, ISO, and other styles

41

Ali Mohamed, Kalaweesh, and Sahlah Khorshid Abbas. "Vitamin D Deficiency in Iraqi Women with Hashimoto Thyroiditis." Tikrit Journal of Pure Science 30, no. 2 (2025): 34–43. https://doi.org/10.25130/tjps.v31i2.1758.

Full text

Abstract:

One kind of autoimmune thyroid disease is Hashimoto's thyroiditis (HT), which is more frequent in women than in males. The purpose of our study was to demonstrate any possible variations in vitamin D levels between ladies with HT and healthy women. METHODS: Fifty healthy Individuals (HI) and fifty HT patients made up the research group of 100 volunteers. Anti-thyroid peroxidase antibody (TPO-Ab) and anti-thyroglobulin antibody (Tg-Ab) levels were used to diagnose HT. The amounts of thyroid-stimulating hormone (TSH), free thyroxin (fT4), free triiodothyronine (fT3) and Vitamin D (Vit-D) were al

APA, Harvard, Vancouver, ISO, and other styles

42

Hitchon, Carol A., Xiaobo Meng, Hani S. El Gabalawy, and Linda Larcombe. "Human host defence peptide LL37 and anti-cyclic citrullinated peptide antibody in early inflammatory arthritis." RMD Open 5, no. 1 (2019): e000874. http://dx.doi.org/10.1136/rmdopen-2018-000874.

Full text

Abstract:

ObjectiveAntibodies to citrullinated peptides (anti-CCP) develop in individuals predisposed to rheumatoid arthritis (RA). Neutrophil extracellular traps are a major source of citrullinated antigens and the immunomodulatory host defence peptide LL-37. Vitamin D regulates LL-37 expression. This study assessed the associations of LL-37 and anti-CCP, vitamin D metabolites and vitamin D receptor (VDR) polymorphisms in early inflammatory arthritis (EIA).MethodsSerum LL-37, 25-hydroxy-vitamin D (25OHvitD) and anti-CCP were measured by ELISA in treatment naïve EIA (n = 181). VDR single nucleotide poly

APA, Harvard, Vancouver, ISO, and other styles

43

Hansen, Ryan, and Joseph Balthasar. "Intravenous Immunoglobulin Mediates an Increase in Anti-Platelet Antibody Clearance via the FcRn Receptor." Thrombosis and Haemostasis 88, no. 12 (2002): 898–99. http://dx.doi.org/10.1055/s-0037-1613331.

Full text

Abstract:

SummaryWe have recently shown that intravenous immunoglobulin (IVIG) therapy leads to an increased rate of anti-platelet antibody clearance in an animal model of immune thrombocytopenia. The present study was performed to confirm the importance of the FcRn receptor in mediating this effect of IVIG. The pharmacokinetics of an anti-platelet antibody, 7E3, were studied in mice lacking expression of FcRn and in control mice, both in the presence and absence of IVIG. IVIG increased the clearance of 7E3 in mice with functioning FcRn receptors, with an average clearance value of 14.4 ± 1.4 ml/d/kg in

APA, Harvard, Vancouver, ISO, and other styles

44

Cowan, Clarissa, Alexander V. Philipovskiy, Christine R. Wulff-Strobel, Zhan Ye, and Susan C. Straley. "Anti-LcrV Antibody Inhibits Delivery of Yops by Yersinia pestis KIM5 by Directly Promoting Phagocytosis." Infection and Immunity 73, no. 9 (2005): 6127–37. http://dx.doi.org/10.1128/iai.73.9.6127-6137.2005.

Full text

Abstract:

ABSTRACT LcrV of Yersinia pestis is a major protective antigen proposed for inclusion in subunit plague vaccines. One way that anti-LcrV antibody is thought to protect is by inhibiting the delivery of toxins called Yops to host cells. The present study characterizes the relation between this inhibition and the phagocytosis of the bacteria. J774A.1 cells were infected with Y. pestis KIM5 in the presence of a protective polyclonal anti-LcrV antibody or a nonprotective polyclonal anti-YopM antibody, and delivery of YopH and YopE into the cytoplasm was assayed by immunoblotting. The ability to inh

APA, Harvard, Vancouver, ISO, and other styles

45

An, Hyun Hyung, Jean Ann Maguire, Alyssa Gagne, et al. "Detection of Rh Antibodies in Patient Plasma Using Genome Engineered Induced Pluripotent Stem Cell-Derived Red Cells." Blood 138, Supplement 1 (2021): 350. http://dx.doi.org/10.1182/blood-2021-151202.

Full text

Abstract:

Abstract Background: Despite transfusion of Rh matched red cells for patients with sickle cell disease, Rh alloimmunization remains a persistent challenge. Rh specificities can be complex, resulting from RH genetic diversity found in patients and donors. Antibody identification is hampered by the lack of appropriate reagent red cells, especially those that can identify antibodies against high prevalence or low prevalence Rh antigens. We used human induced pluripotent stem cells (iPSCs) with the goal of producing renewable red cell reagents to both screen for Rh alloimmunization and to aid comp

APA, Harvard, Vancouver, ISO, and other styles

46

Suyama, K., and J. Goldstein. "Antibody produced against isolated Rh(D) polypeptide reacts with other Rh-related antigens." Blood 72, no. 5 (1988): 1622–26. http://dx.doi.org/10.1182/blood.v72.5.1622.1622.

Full text

Abstract:

Abstract Rh(D) antigen-containing polypeptide was prepared by immune precipitation of intact cDE/cDE erythrocytes by using a high-titer preparation of polyclonal anti-D. when isolated Rh(D) polypeptide was administered to rabbits, antibody was produced that was unresponsive toward Rh-positive and -negative cells but reacted strongly with the immunogen in enzyme-linked immunosorbent assay-type immunobinding and Western blot immunostaining assays. Rabbit antibody also immunostains isolated Rh(c) polypeptide as well as the Rh antigen-containing components of sodium dodecyl sulfate-polyacrylamide

APA, Harvard, Vancouver, ISO, and other styles

47

Suyama, K., and J. Goldstein. "Antibody produced against isolated Rh(D) polypeptide reacts with other Rh-related antigens." Blood 72, no. 5 (1988): 1622–26. http://dx.doi.org/10.1182/blood.v72.5.1622.bloodjournal7251622.

Full text

Abstract:

Rh(D) antigen-containing polypeptide was prepared by immune precipitation of intact cDE/cDE erythrocytes by using a high-titer preparation of polyclonal anti-D. when isolated Rh(D) polypeptide was administered to rabbits, antibody was produced that was unresponsive toward Rh-positive and -negative cells but reacted strongly with the immunogen in enzyme-linked immunosorbent assay-type immunobinding and Western blot immunostaining assays. Rabbit antibody also immunostains isolated Rh(c) polypeptide as well as the Rh antigen-containing components of sodium dodecyl sulfate-polyacrylamide gel elect

APA, Harvard, Vancouver, ISO, and other styles

48

Calapkulu, Murat, Muhammed Erkam Sencar, Davut Sakiz, Ilknur Ozturk Unsal, Mustafa Ozbek, and Erman Cakal. "THE IMPORTANCE OF VITAMIN D LEVEL IN SUBACUTE THYROIDITIS DISEASE AND THE EFFECT OF VITAMIN D ON DISEASE PROGNOSIS." Endocrine Practice 26, no. 10 (2020): 1062–69. http://dx.doi.org/10.4158/ep-2020-0046.

Full text

Abstract:

Objective: Subacute thyroiditis (SAT) is an inflammatory thyroid disease that manifests with severe pain. The presence of the vitamin D receptor in immune system cells shows that vitamin D deficiency can trigger inflammatory diseases. The aim of the present study was to determine the prevalence of vitamin D deficiency in SAT patients, and the relationship between vitamin D level and permanent hypothyroidism and recurrence rate. Methods: In this retrospective study, 25-hydroxyvitamin D (25[OH]D) levels of 170 SAT patients and 86 control subjects were compared. Results: The 25(OH)D levels were s

APA, Harvard, Vancouver, ISO, and other styles

49

Priyadharshini, BS Suganya. "Anti-N-methyl-D-aspartate Receptor Antibody Encephalitis: A Psychiatric Presentation." Eastern Journal of Psychiatry 23, no. 1 (2021): 32–33. http://dx.doi.org/10.5005/jp-journals-11001-0001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Millichap, J. J., J. L. Goldstein, L. C. Laux, D. R. Nordli, C. V. Stack, and M. S. Wainwright. "Ictal Asystole and Anti-N-Methyl-D-aspartate Receptor Antibody Encephalitis." PEDIATRICS 127, no. 3 (2011): e781-e786. http://dx.doi.org/10.1542/peds.2010-2080.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!