Academic literature on the topic 'Anti-hyperglycemic activity'

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Journal articles on the topic "Anti-hyperglycemic activity"

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Bafail, Rawan S. M., and Waad A. Samman. "Anti-parkinsonian, anti-inflammatory, anti-microbial, analgesic, anti-hyperglycemic and anticancer activities of poly-fused ring pyrimidine derivatives." Tropical Journal of Pharmaceutical Research 23, no. 1 (2024): 67–75. http://dx.doi.org/10.4314/tjpr.v23i1.9.

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Purpose: To investigate the anti-inflammatory, anti-cancer, anti-parkinsonian, anti-microbial, analgesic, and anti-hyperglycemic properties of a variety of poly-fused pyrimidine derivatives.
 Methods: A novel series of fused pyrimidine derivatives 1-6 were synthesized by reacting amino pyrazole derivatives with active methylene derivatives to give the corresponding compounds 1-6. Anti-parkinsonian activity was investigated with benzotropene as a reference drug, anti-inflammatory effect in mice was evaluated using carrageenan in paw edema with indomethacin as reference drug, anti-microbial
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Choudhary, Shailesh Kumar, Gagan Chhabra, Dipali Sharma, Aruna Vashishta, Sujata Ohri, and Aparna Dixit. "Comprehensive Evaluation of Anti-hyperglycemic Activity of FractionatedMomordica charantiaSeed Extract in Alloxan-Induced Diabetic Rats." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/293650.

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The present study evaluates anti-hyperglycemic activity of fractionatedMomordica charantia(bitter gourd) seed extracts. Fasting blood glucose levels were evaluated before and after administration of different fractions of the seed extract. Among the three fractions tested, fraction Mc-3 (15 mg/kg b.wt.) showed the maximum anti-hyperglycemic activity and reduced blood glucose levels in experimental diabetic rats significantly. The activities of the key regulatory enzymes of glucose metabolism (hexokinase, pyruvate kinase, lactate dehydrogenase, and glucose-6-phosphate dehydrogenase) were determ
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Bellamakondi, Pavan Kumar, Ashok Godavarthi, and Mohammed Ibrahim. "Anti-hyperglycemic activity of Caralluma umbellata Haw." BioImpacts 4, no. 3 (2017): 113–16. http://dx.doi.org/10.15171/bi.2014.003.

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Md., Lokman Hossain, Monjur-Al-Hossain A.S.M., Saha Subarna, and Kumar Sadhu Samir. "Assessment of Biological Activity on Cirsium arvense L." Algerian Journal of Natural Products 5, no. 1 (2017): 417–26. https://doi.org/10.5281/zenodo.824566.

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This study was aimed at evaluating antibacterial, cytotoxic, anthelmintic and anti-hyperglycemic activity of aerial part of <em>Cirsium arvense</em>. Antibacterial activity was determined by disc diffusion method at the concentration of 200, 250 and 500 µg/disc. Cytotoxic and anthelmintic activity was carried out according to Meyer and Gade method with slight modification respectively. The anti-hyperglycemic activity was determined by the method followed by Djilani. The extract showed dose dependent antibacterial activity against the experimental bacterial strains except <em>Staphylococcus epi
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Priya, Bhanu, Manoj Gahlot, and Punam Joshi. "Screening of Anti-hyperglycemic Activity of Kigelia africana on Alloxan-Induced Diabetic Rats." Indian Journal of Applied Research 4, no. 6 (2011): 448–51. http://dx.doi.org/10.15373/2249555x/june2014/140.

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Zhang, Baoshun, Tingting Chen, Zhu Chen, et al. "Synthesis and anti-hyperglycemic activity of hesperidin derivatives." Bioorganic & Medicinal Chemistry Letters 22, no. 23 (2012): 7194–97. http://dx.doi.org/10.1016/j.bmcl.2012.09.049.

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Ruíz-Aguilar, Isay, Ofelia Gabriela Meza-Márquez, Guillermo Osorio-Revilla, Tzayhri Gallardo-Velázquez, and Oswaldo Arturo Ramos-Monroy. "Phytochemical Compounds, and Antioxidant, Anti-Hyperglycemic, and Anti-Inflammatory Activity of Microencapsulated Garambullo (Myrtillocactus geometrizans) Extract During In Vitro Digestion and Storage." Processes 12, no. 11 (2024): 2526. http://dx.doi.org/10.3390/pr12112526.

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Garambullo fruit (Myrtillocactus geometrizans) is a rich source of phytochemical compounds that exhibit antioxidant, anti-hyperglycemic, and anti-inflammatory activities, helping to prevent diseases associated with oxidative stress. The objective of this study was to evaluate phenolic compound (PC), betalain (BL), betaxanthin (BX), and betacyanin (BC) contents, and in vitro biological activities (antioxidant, anti-hyperglycemic, and anti-inflammatory) in microencapsulated garambullo extract during in vitro gastrointestinal digestion and storage. Microencapsulation was performed using spray dry
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Bunyakitcharoen, Athit, Weerakit Taychaworaditsakul, Seewaboon Sireeratawong, and Sunee Chansakaow. "Anti-Hyperglycemic Effects of Thai Herbal Medicines." Plants 13, no. 20 (2024): 2862. http://dx.doi.org/10.3390/plants13202862.

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This study aims to investigate selected medicinal plants’ anti-oxidative and antihyperglycemic activities to develop an effective remedy for lowering blood glucose levels and/or reducing diabetes complications. Thai medicinal plants, reported to have blood sugar-lowering effects, were selected for the study: Coccinia grandis, Gymnema inodorum, Gynostemma pentaphyllum, Hibiscus sabdariffa, Momordica charantia, Morus alba, and Zingiber officinale. Each species was extracted by Soxhlet’s extraction using ethanol as solvent. The ethanolic crude extract of each species was then evaluated for its ph
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Minh Trang, Vu, Bui Van Trung, Phan Minh Giang, Do Thi Viet Huong, and Nguyen Tien Son. "Antiglycemic Activity of Vietnamese Scutellaria barbata Extract in Streptozotocin-Induced Diabetic Mice." Journal of Food Biochemistry 2024 (May 18, 2024): 1–8. http://dx.doi.org/10.1155/2024/8039043.

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Scutellariabarbata D. Don (S. barbata), a medicinal herb commonly used in traditional Chinese and Korean medicine, consists of bioactive neoclerodanes and flavonoids. However, its anti-hyperglycemic activity has not been reported. In this work, we used bioassay-guided fractionation to find effective anti-hyperglycemic fractions of S. barbata. The chemical components of these fractions were also determined structurally; they are scutellarin (1), luteolin (2), naringenin (3), tricin (4), baicalein (5), baicalin (6), apigenin (7), and wogonin (8). The most potent fraction SB6 consisting of flavon
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Prateek, Pandey1* Shradha Pandey2 Alok Mukerjee1. "ATTENUATION OF HYPERGLYCEMIA IN STREPTOZOTOCIN-INDUCED DIABETIC RATS BY BAUHINIA VARIEGATA FLOWER EXTRACT." Journal of Pharma Research 8, no. 11 (2019): 676–83. https://doi.org/10.5281/zenodo.3595210.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>o evaluate the anti-hyperglycemic activity of ethanolic extract of Bauhinia variegata flower (BVE) using streptozotocin (STZ) model and anti-oxidant activity of BVE evaluated by in-vitro methods. Ethanolic extract of Bauhinia variegata flower (BVE) 200 and 400 mg/kg body weight was administered orally according to different groups of animals once a daily for 21 days. Blood glucose levels were estimated at 0, 7<sup>th</sup>, 14<sup>th</sup> and 21<sup>st</sup> day by glucometer (one-touch) and on 21<sup>st</sup> day biochemical p
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Dissertations / Theses on the topic "Anti-hyperglycemic activity"

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Huang, Teng I., and 黃騰億. "Studies on the Mechanism of Anti-hyperglycemic Activity of Cordyceps sinensis in Diabetic rats." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/63169071144935736713.

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碩士<br>東海大學<br>食品科學系<br>93<br>Diabetes mellitus is one of the life-threatening chronic diseases and has become a top-four killer in Taiwan(Department of health, 2004). Cordyceps sinensis is one of the most precious Chinese herbs and may play various physiological roles in restoring the body’s homeostasis. In addition to those well-known functions, recent evidences suggested that extracts of Cordyceps, most probably polysaccharide fractions, may have help to alleviate hyperglycemia in diabetic animals. However the underlying molecular mechanisms have not been addressed. In this study, we attemp
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Huang, Yu-Ling, and 黃鈺玲. "Studies on Mechanism of Anti-hyperglycemic Activity of Cordyceps sinensis in Muscle of Diabetic Rats." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/59251127120754048288.

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碩士<br>東海大學<br>食品科學系<br>96<br>Diabetes mellitus is a prevailing endocrine disease caused by a low level of insulin or insulin resistance, and is characterized by hyperglycemia. Hyperglycemia can result in many complications, which could be minimized through a better control of blood sugar. Previous studies have shown that both natural and cultured Cordyceps sinensis could ameliorate hyperglycemia in streptozotocin-induced diabetic rats, despite of an impaired insulin secretion. In addition to insulin signaling, signaling pathway mediated by adiponectin, an adipokine is secreted by adipocytes, m
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Cheng, Ju-Hsiang, and 鄭汝翔. "Studies on Mechanism of Anti-hyperglycemic Activity of Tremella mesenterica Retz.:Fr. in Liver of Diabetic RatsTremella mesenterica Retz.:Fr. in Liver of Diabetic RatsStudies on Mechanism of Anti-hyperglycemic Activity of Tremella mesenterica Retz." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/77736759319501140323.

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碩士<br>東海大學<br>食品科學系<br>98<br>Diabetes, due to insufficient secretion or malfunction of insulin, is an endocrine disease. The pathogenesis of diabetes is complicated and still unclarified. Because of delicate diet, the global prevalence and young population increased dramatically in recent years. Studies indicate that the genetic deposits and lifestyles might influence the progression of diabetes, especially lack of exercises and energy excess which would ultimately result in insulin resistance and type II diabetes without proper intervention. Diabetic patients with long-term abnormal blood glu
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Lai, Huei-Lan, and 賴惠蘭. "Studies on mechanism of anti-hyperglycemic activity of Tremella mesenterica retz.:Fr. in liver of diabetic rats." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/13888152507415582860.

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碩士<br>東海大學<br>食品科學系<br>98<br>Diabetes mellitus is the metabolic abnormality resulted from multiple causes, and the incidence of potent patients with insulin resistance is far more than that of the dia- betes patients. It would be beneficial in reducing the cost of future medical care by improving the status of high blood sugar before irreversible organ lesions. Skeletal muscle is a major tissue for glucose consumption, and glucose uptake by the regula- tion of insulin. The regulation of blood sugar, in addition to insulin signaling, is also mediated by adiponectin, an adipokine secreted by adi
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Book chapters on the topic "Anti-hyperglycemic activity"

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Sansi, Manish Singh, Daraksha Iram, Kapil Singh Narayan, Sandeep Kumar, Om Prakash, and Dipanjan Misra. "Antidiabetic Activity (Anti-Hyperglycemic Activity, Anti-Hyperlipidemic Activity)/Agents From Medicinal Plants." In Advanced Pharmacological Uses of Medicinal Plants and Natural Products. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2094-9.ch002.

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Diabetes mellitus (DM) is a chronic disease caused by inherited or acquired deficiency in insulin secretion and by decreased insulin secretion by the organ. Insulin deficiency causes the DM. Synthetic drugs are widely used in the treatment of diabetes, but they have some side effects. The antihyperglycemic and antihyperlipedemic effects of the plants are related to their ability to maintain pancreatic function. Medicinal plants constituents such as glycosides, alkaloids, terpenoids, and flavonoids mitigate DM. B. ciliata inhibits the α-glucosidase and α-amylase. Cinnamon extracts improve insul
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Sansi, Manish Singh, Daraksha Iram, Kapil Singh Narayan, Sandeep Kumar, Om Prakash, and Dipanjan Misra. "Antidiabetic Activity (Anti-Hyperglycemic Activity, Anti-Hyperlipidemic Activity)/Agents From Medicinal Plants." In Research Anthology on Recent Advancements in Ethnopharmacology and Nutraceuticals. IGI Global, 2022. http://dx.doi.org/10.4018/978-1-6684-3546-5.ch014.

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Diabetes mellitus (DM) is a chronic disease caused by inherited or acquired deficiency in insulin secretion and by decreased insulin secretion by the organ. Insulin deficiency causes the DM. Synthetic drugs are widely used in the treatment of diabetes, but they have some side effects. The antihyperglycemic and antihyperlipedemic effects of the plants are related to their ability to maintain pancreatic function. Medicinal plants constituents such as glycosides, alkaloids, terpenoids, and flavonoids mitigate DM. B. ciliata inhibits the α-glucosidase and α-amylase. Cinnamon extracts improve insul
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McGrowder, Donovan Anthony, Fabian G. Miller, Chukwuemeka Nwokocha, et al. "Medical Herbs and the Treatment of Diabetes Mellitus." In Treating Endocrine and Metabolic Disorders With Herbal Medicines. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-4808-0.ch003.

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Diabetes mellitus is a chronic metabolic disorder that affects millions of persons worldwide, and if uncontrolled may cause cardiovascular disease, retinopathy, or chronic kidney disease. Effective therapeutic management of diabetes mellitus involves the use of mainly oral hypoglycemic drugs whose mechanism of action includes improved insulin secretion, reduced insulin resistance, or increased glucose uptake. There is growing exploration of medicinal herbs as potential therapeutic sources for the management of type 2 diabetes mellitus and compared with conventional oral hypoglycemic drugs they
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Kumar Dash, Deepak, Chandra Kishore Tyagi, Anil Kumar Sahu, and Vaibhav Tripathi. "Revisiting the Medicinal Value of Terpenes and Terpenoids." In Revisiting Plant Biostimulants [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102612.

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Nowadays, plant-based chemicals have drawn the attention of pharmacy researchers due to their potent biological activity against various ailments. In this series, terpenes and terpenoids are gaining popularity among drug researchers gradually. Terpenes are naturally occurring large and varied class of hydrocarbons substances produced by a wide variety of plants including fruits, vegetables, flowers and some animals. Their concentration is generally high in plants. A broad range of the biological properties of terpenoids includes cancer chemo-preventive effects, antimicrobial, antifungal, antiv
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Chakraborty, Avijit, Shamim Hossain Mandal, Soumik Debnath, and Jaya Bandyopadhyay. "Exploring the Potent Anticancer Activity of Andrographis paniculata (Kalmegh): Mechanisms, Applications and Therapeutic Implications." In Life as Basic Science: An Overview and Prospects for the Future [Volume: 1]. International Academic Publishing House (IAPH), 2024. http://dx.doi.org/10.52756/lbsopf.2024.e01.001.

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Despite advancements in therapeutic approaches, cancer appears to be biggest cause of death globally. Consequently, the primary focus should be on early cancer detection, developing the best possible treatment plan to extend the patient’s life, and continuing the hunt for more potent and targeted drugs to treat various cancer types. Stronger anti-cancer drugs have been developed as a result of the current change in natural chemical research towards sophisticated and molecular-level understandings. Infertility, ovarian failure, liver, renal, and heart toxicity, as well as immunosuppressive side
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Gunathilaka, Thilina, Lakshika Rangee Keertihirathna, and Dinithi Peiris. "Advanced Pharmacological Uses of Marine Algae as an Anti-Diabetic Therapy." In Pharmacognosy - Medicinal Plants [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96807.

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Marine seaweeds are a promising source of bioactive secondary metabolites that can be utilized in drug development and nutraceuticals. Diabetes mellitus is a leading non-communicable disease, and it is the third leading cause of death worldwide. Among the types of diabetes, type 2 became the major health problem as it is associated with severe health complications. Since available oral hypoglycemic drugs cause several adverse effects, it is worth searching for a natural cure with fewer or no side effects that may benefit patients with type 2 diabetes. Among the marine seaweeds, brown and red s
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Conference papers on the topic "Anti-hyperglycemic activity"

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Balcazar, N., S. Acin, F. Ruiz, Y. Lopera, and D. Colorado. "Anti-hyperglycemic activity of anthocyanins loaded in non-ionic niosomes." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608374.

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Balcazar-Morales, N., A. Guillen, L. Munoz Diana, R. Ramirez-Pineda Jose, L. Montoya-Perez Guillermo, and S. Acin-Martinez. "Anti-hyperglycemic/antidiabetic activity of Serjanic acid obtained from Cecropia telenitida." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608094.

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Marinho, Lorrany Miranda, Monique Barreto Santos, Renata Marenda Ferreira, Maria Eugenia Araujo Silva Oliveira, Carlos Piler, and Cristina Yoshie Takeiti. "ANTIOXIDANT CAPACITY AND ANTI-HYPERGLYCEMIC ACTIVITY OF MILLET-BASED BREADS MADE BY TWO BAKING PROCESS." In VI Simpósio de Alimentos e Nutrição. Even3, 2024. http://dx.doi.org/10.29327/simposio-alimentos-nutricao.810487.

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Liu, Yun-Tao, Qian-Qian Tang, Yu-Xian You, et al. "The Separation and Purification of Se-enriched Mycelium Polysaccharides of Catathelasma Ventricosum and Their Anti-hyperglycemic and Antioxidant Activity." In The International Conference on Biological Sciences and Technology. Atlantis Press, 2016. http://dx.doi.org/10.2991/bst-16.2016.9.

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