Log in

Relevant bibliographies by topics / Anti-inflammatory signaling / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Anti-inflammatory signaling.

Dissertations / Theses on the topic 'Anti-inflammatory signaling'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 28 dissertations / theses for your research on the topic 'Anti-inflammatory signaling.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Vale, Duarte Pereira Claudia Patricia. "Inflammatory Wnt5A signaling in macrophages as novel target for anti-inflammatory action of activated protein C /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000278496.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Parthasarathy, Upasana. "Identifying epitopes of anti-FcaRI monoclonal antibodies on FcaRI ectodomain that trigger the anti-inflammatory ITAMi signaling pathway." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1418910350.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Rossato, Elisabetta. "Anti-inflammatory role of monomeric IgA through the inhibitory FcαRI-ITAMi signaling in rheumatoid arthritis". Paris 7, 2014. http://www.theses.fr/2014PA077056.

Full text

Abstract:

De par leur hétérogénéité, les IgA possèdent des propriétés pro- ou anti-inflammatoires et contribuent à l'homéostasie immunitaire. Ces activités dépendent de l'interaction des IgA avec le récepteur RFcal contenant le motif ITAM (immunoreceptor tyrosine-based motif). Les IgA sous forme de complexes entraînent une activation pro-inflammatoire, tandis qu'en l'absence d'antigène, celles-ci (ou le fragment Fab d'un anticorps anti-RFcat) engendrent un signal anti-inflammatoire (nommé ITAMi ou ITAM inhibiteur) capable d'inhiber l'activation des récepteurs hétérologues. L'ITAMi nécessite, au niveau d

APA, Harvard, Vancouver, ISO, and other styles

4

Gatbonton-Schwager, Tonibelle N. "Biological and Chemical Analysis of Small Molecule Activators of Anti-inflammatory and Antioxidant Nrf2-Keap1 Signaling." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1390560628.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Davarya, Shekar Ligia. "Inflammatory and Thrombotic Responses to Microbial Products in Fetal Vessels Are Mediated through Divergent Toll-Like Receptor Signaling Pathways: Implications in Fetal Inflammatory Response Syndrome." Yale University, 2008. http://ymtdl.med.yale.edu/theses/available/etd-08072007-132134/.

Full text

Abstract:

Placental vessels and the umbilical circulatory network function to carry oxygen and nutrients to the fetus. It is at this level that placental lesions such as villitis, obliterative vasculopathy, and thrombotic vasculopathy have been observed in association with fetal inflammatory response syndrome (FIRS) and cerebral palsy. We used human umbilical vein endothelial cells (HUVECs) as a model to study the regulation of inflammation and thrombosis in fetal vessels by microbial products. In this thesis we measured interleukin-8 (IL-8) and tissue factor (TF) expression by HUVECs treated with lipop

APA, Harvard, Vancouver, ISO, and other styles

6

Ma, Loretta T. K. "PKA Signaling in ABCA1 Function: A Role in Modulation of Cholesterol Efflux and Macrophage Inflammation." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/26272.

Full text

Abstract:

Formation of lipid-laden macrophage foam cells and inflammation are the central components in the initiation and progression of atherosclerosis. ABCA1 is well established as an anti-atherogenic factor that facilitates cellular cholesterol and phospholipid efflux, promotes reverse cholesterol transport, and suppresses pro-inflammatory cytokine secretion. Through these functions, ABCA1 is capable of reducing the lipid burden in atherosclerotic plaque. PKA signaling is an integral factor in promoting many anti-atherogenic functions of ABCA1; however, mechanistic aspects of PKA signaling associate

APA, Harvard, Vancouver, ISO, and other styles

7

Loveridge, Carolyn J. "The effects of nonsteroidal anti-inflammatory drugs on nuclear factor-kappaB and Beta-catenin signaling in colorectal cancer cells." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/29229.

Full text

Abstract:

The first research strand in this thesis was to determine whether non-aspirin NSAIDs induce apoptosis of colorectal cancer cells via modulation of the NF-κB pathway and to elucidate the upstream mechanisms involved. Experimental evidence presented here shows that sulindac, sulindac sulfone and indomethacin cause NF-κB pathway activation. It was found that non-aspirin NSAIDs induce nucleolar translocation of the NF-κB component, RelA, repression of NF-κB driven transcriptional activity and apoptosis. Furthermore, in a similar manner to aspirin, nucleolar translocation of Re1A was demonstrated t

APA, Harvard, Vancouver, ISO, and other styles

8

Pangburn, Heather Ann. "Effects of the non-steroidal anti-inflammatory drug (NSAID) sulindac on epidermal growth factor receptor (EGFR) expression and signaling in colorectal cancer /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2007.

Find full text

Abstract:

Thesis (Ph.D. in Toxicology) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 156-176). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;

APA, Harvard, Vancouver, ISO, and other styles

9

Konarski, Yulia. "SHP-1/ Src Complex is a Master Regulator of the IL-12/IL-23 pro- and IL-10/IL-27 Anti-inflammatory Axis in TLR4-activated Signaling Pathways in Human Monocytes and Macrophages." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/25999.

Full text

Abstract:

Although the etiology surrounding many autoimmune diseases remains unknown, the underlying characteristic of many of these diseases is a disruption in the balance of pro- and anti- inflammatory cytokines It is well established that the dysregulation of the IL-12 family of cytokines, an increase in IL-12/IL-23 and a decrease in IL-27 production has been implicated in these conditions. We used ELISA, RT-PCR, Immunofluorescence and Western immunoblotting in conjunction with pharmalogical inhibitors and siRNA to demonstrate the role of SHP-1/Src in the regulation of IL-12, IL-23, IL-27 and IL-10 i

APA, Harvard, Vancouver, ISO, and other styles

10

Kaci, Ghalia. "Caractérisation des propriétés anti-inflammatoires de souches commensales de Streptococcus salivarius." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-01069898.

Full text

Abstract:

Les bactéries commensales digestives jouent un rôle primordial dans l'homéostasie épithéliale et la santé de l'hôte, avec notamment un rôle modulateur du système immunitaire. Des effets bénéfiques dans le traitement des pathologies inflammatoires intestinales ont été caractérisés chez certaines souches de bactéries commensales. La compréhension de ces effets dans le maintien de l'homéostasie intestinale repose sur la connaissance des interactions entre les bactéries, l'épithélium intestinal et le système immunitaire muqueux. Streptococcus salivarius est l'un des premiers colonisateurs de la ca

APA, Harvard, Vancouver, ISO, and other styles

11

Williams, Lynn Michelle. "A comparison of interleukin-10 and lipopolysaccharide signalling in monocytes." Thesis, Imperial College London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264968.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Brodin, Patcha Veronika. "Pro- and anti-inflammatory regulation of β2 integrin signalling in human neutrophils". Doctoral thesis, Linköpings universitet, Medicinsk mikrobiologi, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-9661.

Full text

Abstract:

The body is under constant attack from pathogens trying to slip by our immune defence. If the barrier is breached, invading pathogens enter the tissues and cause inflammation. During this process neutrophils, constituting the first line of defence, leave the bloodstream and seek out and kill the invading pathogens. The mechanisms leading to activation of receptors on neutrophils must be closely orchestrated. Pro- and anti-inflammatory substances can influence the outcome of the inflammation process by affecting the involved players. If not well balanced, inflammatory diseases, such as atherosc

APA, Harvard, Vancouver, ISO, and other styles

13

Chew, Angela Christine. "The anti-proliferative effects of thiazolidinediones and non-steriodal anti-inflammatory drugs on androgen-independent prostate cancer." University of Western Australia. School of Medicine and Pharmacology, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0200.

Full text

Abstract:

[Truncated abstract] In recent years a better understanding of the biology of PPAR , a nuclear transcription factor, has emerged, leading to a resurgence in targeting PPAR for chemotherapy. The family of synthetic PPAR agonists, the thiazolidinediones (TZDs), and non-steroidal anti-inflammatory drugs (NSAIDs) have been implicated in the inhibition of cell proliferation, apoptosis and cell cycle arrest of androgen-sensitive (LNCaP) and androgen-independent (PC-3 and DU145) prostate cancer cells generating much interest in their use for potential curative cancer therapies. In light of the pote

APA, Harvard, Vancouver, ISO, and other styles

14

Karnam, Anupama. "Role of Wnt/β-catenin pathway in the anti-inflammatory mechanism of therapeutic normal immunoglobulins Wuchereria bancrofti filaria activates human dendritic cells and polarizes T helper 1 and regulatory T cells via toll-like receptor 4 Regulatory T cells induce activation rather than suppression of human basophils". Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS642.

Full text

Abstract:

Les immunoglobulines polyclonales intraveineuses (IVIG) sont préparées à partir de plasmas provenant de plusieurs milliers de donneurs sains et utilisées comme traitement dans de nombreuses maladies inflammatoires et autoimmunes. Lors de ma thèse, j’ai investigué si cette thérapie pouvait interférer avec la détection sérique du virus Zika chez des patients atteints du syndrome de Guillain-Barré (GBS). J’ai démontré que la thérapie par IVIG n’interférait pas avec la détection sérique du virus dans le plasma des patients atteints de GBS suivant un traitement aux IVIG. Contrairement aux souris, l

APA, Harvard, Vancouver, ISO, and other styles

15

Manoj, Sivanjaa. "Characterisation of the interleukin-4 signalling cascade involved in the induction of cyclooxygenase-2 and the polarisation of macrophages into an anti-inflammatory phenotype." Thesis, University of East London, 2018. http://roar.uel.ac.uk/7382/.

Full text

Abstract:

The inflammatory response can be broken down into the pro-inflammatory phase, followed by the resolution phase. Both phases are regulated by the expression or release of immunomodulatory mediators such as cytokines e.g. TNFα and IL-10. The two phases are also associated with different macrophage polarization states where the M1 phenotype is seen during the pro-inflammatory phase and M2 during resolution. Whereas much focus has been on the pro-inflammatory phase, more recently, emphasis has been placed on initiating the resolution phase of inflammation. Historically one of the classical signs o

APA, Harvard, Vancouver, ISO, and other styles

16

Lie, Chun-Yo, and 賴俊佑. "Effects of Phytochemicals on Proinflammatory and Anti-inflammatory Signaling Pathways in HASMC Model." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/62056270364345547203.

Full text

Abstract:

碩士<br>中國文化大學<br>生物科技研究所<br>97<br>This research mainly to investigate the effect of phytochemical quercetin, cyanidin, chlorophyllin, chlorophyll a, chorophyll b on inflammatory signaling pathways of proinflammatory factors and anti-inflammatory factors in HASMC model.To analysis nuclear transcription factors includes NF-κB(nuclear factors-κB), STAT3(signal transducer and activator of transcription protein 3), SMAD3/4(derived from SMA-small body size and MAD-mothers against decapentaplegic3/4). Treated HASMC with 0, 2.5, 5, 10, 20, 40, 50μM aspirin, quercetin, cyaniding, chlorophyllin, chloroph

APA, Harvard, Vancouver, ISO, and other styles

17

Hsieh, Wen Bin, and 謝文斌. "Effects of Phytochemicals on Proinflammatory and Anti-inflammatory Signaling Pathways in HAEC Model." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/29570257644833068322.

Full text

Abstract:

碩士<br>中國文化大學<br>生物科技研究所<br>96<br>Abstract This research discussed the main natural anti-oxidant materials such as chlorophyllin, chlorophyll a, chlorophyll b, cyanidin, quercetin effects on pro-inflammatory and anti-inflammatory signaling pathways in human aortic endothelial cells (HAEC) model and its underlying mechanisms. The pro-inflammatory factors include interleukin 8( IL-8), monocyte chemotactic protein 1 (MCP-1), Cluster of differentiation 40(CD40); the nuclear transcription factors include nuclear factor-kappa B (NF-κB), activating protein-1(AP-1) and signal transducer and activator o

APA, Harvard, Vancouver, ISO, and other styles

18

Marotta, Anthony. "Dysregulation of integrin-linked kinase (ILK) signaling during colorectal carcinogenesis : modulation of signaling pathways by non-steroidal anti-inflammatory drugs (NSAID)." Thesis, 2002. http://hdl.handle.net/2429/13101.

Full text

Abstract:

One of the most common events involved in the development of human colon cancer is the mutation of the adenomatous polyposis coli (APC) gene. This protein through its interactions with Axin and GSK3β, serves to regulate the cytosolic levels of β-catenin. Mutation of the APC gene, which impairs complex formation, results in the stabilization of β-catenin. Stabilization is believed to coincide with the translocation of β-catenin to the nucleus, where it up-regulates a number of genes implicated in oncogenesis. Interestingly, stable over-expression of the integrin-linked kinase (ILK) in ra

APA, Harvard, Vancouver, ISO, and other styles

19

Weng, Ching-Yi, and 翁菁憶. "Anti-Inflammatory Effect of Glossogyne tenuifolia Is Mediated through Down-Regulating NF-kB and MAPK Signaling Pathways." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/06791194863420101228.

Full text

Abstract:

碩士<br>嘉南藥理科技大學<br>生物科技系暨研究所<br>92<br>Inflammatory response is typically represented by a cascade of vascular and cellular reactions caused by injury and infection. The activation of macrophages is a key event for the initiation and propagation of these defensive reactions. When stimulated with pathologic stimuli or injury, macrophages release nitric oxide, PGE2, TNF-a, IL-1b, IL-6 and IL-12. In addition, T cells secret IFN-g and other pro-inflammatory cytokines that augment defense against invasion. The sustained inflammatory mediator production has been implicated associated with the patholog

APA, Harvard, Vancouver, ISO, and other styles

20

Hsu, Chih Kai, and 許智凱. "Mechanisms underlying anti-inflammatory protein, suppressor of cytokine signaling-3 expression and sphingosine-1-phosphate-induced inflammatory response in human tracheal smooth muscle cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/38948430136649130050.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Imre, Gabriele [Verfasser]. "Anti-apoptotic and pro-inflammatory signaling in cancer cells : status and modulation by chemotherapeutic drugs / vorgelegt von Gabriele Imre." 2007. http://d-nb.info/985024704/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Rutherford, C., C. Speirs, Jamie J. L. Williams, et al. "Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling." 2016. http://hdl.handle.net/10454/10881.

Full text

Abstract:

yes<br>AMP-activated protein kinase (AMPK) is a pivotal regulator of metabolism at the cellular and organismal levels. AMPK also suppresses inflammation. We found that pharmacological activation of AMPK rapidly inhibited the Janus kinase (JAK)–signal transducer and activator of transcription (STAT) pathway in various cells. In vitro kinase assays revealed that AMPK directly phosphorylated two residues (Ser515 and Ser518) within the SH2 domain of JAK1. Activation of AMPK enhanced the interaction between JAK1 and 14-3-3 proteins in cultured vascular endothelial cells and fibroblasts, an ef

APA, Harvard, Vancouver, ISO, and other styles

23

Horvátová, Alžbeta. "Anti-inflammatory effects of ursodeoxycholyl lysophosphatidylethanolamide on THP-1 human macrophages via Toll-like receptor 4." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-351489.

Full text

Abstract:

Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Alžbeta Horvátová Supervisor: prof. PharmDr. Petr Pávek PhD. Title of diploma thesis: Anti-inflammatory effects of ursodeoxycholyl lysophosphatidylethanolamide on THP-1 human macrophages via Toll-like receptor 4 Nonalcoholic steatohepatitis (NASH) became the most common liver disease in developed countries. It is well-known that the level of protectant phosphatidylcholine (PC) is decreased in NASH. The bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide

APA, Harvard, Vancouver, ISO, and other styles

24

Siemoneit, Ulf [Verfasser]. "Anti-inflammatory actions of boswellic acids : identification and critical evaluation of molecular targets and signaling pathways = Entzündungshemmende Wirkungen von Boswelliasäuren / vorgelegt von Ulf Siemoneit." 2009. http://d-nb.info/996706674/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Hsu, Yu An, and 許妤安. "A study on the interferon signaling pathway: the importance of STAT6 in the anti-proliferative effects of type I interferon and the pro-inflammatory effects of miR-155 induced by type II interferon." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/zr3u57.

Full text

Abstract:

博士<br>國立清華大學<br>分子醫學研究所<br>105<br>The interferon (IFN) system is the first line of defence against virus infection in the vertebrates. The infection itself triggers IFN synthesis and secretion. According to the differences of binding receptor. Binds to receptor of IFNAR1 and IFNAR2 chains : type I, which includes IFN-α and IFN-β, and binds to receptor of IFNGR : type II; comprising IFN-γ. In the first study is to evaluate the importance of STAT6 in the anti-proliferative effects of type I interferon. Type I IFN-induced STAT6 has been shown to have anti-proliferative effects in Daudi and B cell

APA, Harvard, Vancouver, ISO, and other styles

26

Busch, F., A. Mobasheri, P. Shayan, C. Lueders, R. Stahlmann, and M. Shakibaei. "Resveratrol modulates interleukin-1beta-induced phosphatidylinositol 3-kinase and nuclear factor kappaB signaling pathways in human tenocytes." 2012. http://hdl.handle.net/10454/5903.

Full text

Abstract:

Resveratrol, an activator of histone deacetylase Sirt-1, has been proposed to have beneficial health effects due to its antioxidant and anti-inflammatory properties. However, the mechanisms underlying the anti-inflammatory effects of resveratrol and the intracellular signaling pathways involved are poorly understood. An in vitro model of human tenocytes was used to examine the mechanism of resveratrol action on IL-1beta-mediated inflammatory signaling. Resveratrol suppressed IL-1beta-induced activation of NF-kappaB and PI3K in a dose- and time-dependent manner. Treatment with resveratrol enhan

APA, Harvard, Vancouver, ISO, and other styles

27

Ribeiro, Daniela Sofia Almeida. "Flavonoids with potential anti-inflammatory activity: in vitro structure/activity studies of their effects in pro-inflammatory signalling systems." Tese, 2014. https://repositorio-aberto.up.pt/handle/10216/77561.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Ribeiro, Daniela Sofia Almeida. "Flavonoids with potential anti-inflammatory activity: in vitro structure/activity studies of their effects in pro-inflammatory signalling systems." Doctoral thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/77561.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!