Academic literature on the topic 'Anti-metastatic effect'

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Journal articles on the topic "Anti-metastatic effect"

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Delgado, Yamixa, Anamaris Torres-Sanchez, Daraishka Perez, et al. "Deferasirox’s Anti-Chemoresistance and Anti-Metastatic Effect on Non-Small Cell Lung Carcinoma." Biomedicines 12, no. 10 (2024): 2272. http://dx.doi.org/10.3390/biomedicines12102272.

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Clinically approved iron chelators, originally designed to address iron overload disorders, have emerged as potential anticancer agents. Deferasirox (Def), a tridentate iron chelator, has demonstrated antiproliferative effects in cancer. Background/Objectives: This study aims to elucidate the mechanism of action of Def and its impact on non-small cell lung carcinoma (NSCLC). Methods: NSCLC A549 cells were treated with Def to assess cytotoxicity, the effect on nuclear and mitochondrial pathways, and iron-containing proteins and genes to evaluate anti-metastasis and chemoresistance. A lung carci
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Mun, Jeong-Geon, Yo-Han Han, Hee-Dong Jeon, et al. "Inhibitory Effect of Gallotannin on Lung Metastasis of Metastatic Colorectal Cancer Cells by Inducing Apoptosis, Cell Cycle Arrest and Autophagy." American Journal of Chinese Medicine 49, no. 06 (2021): 1535–55. http://dx.doi.org/10.1142/s0192415x21500725.

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Colorectal cancer (CRC) is the second most common cause of cancer death in the world, and metastatic CRC is a major cause of cancer death. Gallotannin (GT), a polyphenolic compound, has shown various biological effects such as anti-oxidant, anti-inflammatory, antimicrobial, and antitumor effects. However, the effects of GT on metastatic CRC cells are not completely understood. This study aimed to investigate the anti-metastatic effect of GT and the underlying mechanisms on metastatic CRC cells. Oral administration of GT suppressed the lung metastasis of metastatic CRC cells in the experimental
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Niu, Ying-Cai, Ji-Cheng Liu, Xue-Mei Zhao, and Jun Cao. "A Low Molecular Weight Polysaccharide Isolated from Agaricus blazei Murill (LMPAB) Exhibits Its Anti-Metastatic Effect by Down-Regulating Metalloproteinase-9 and Up-Regulating Nm23-H1." American Journal of Chinese Medicine 37, no. 05 (2009): 909–21. http://dx.doi.org/10.1142/s0192415x09007351.

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The components of Agaricus blazei Murill (AbM) have been shown to possess antitumor potentials. Herein, we attempted to explore the anti-metastatic effect and underlying mechanism of a low molecular weight polysaccharide isolated from AbM (LMPAB). Matrigel invasion assay was applied to evaluate the effect of LMPAB on migration of BEL-7402 hepatic cancer cells in vitro. In vivo, the anti-metastatic effect of LMPAB was investigated in mouse B16 melanoma and a double-grafted SW180 tumor models. mRNA and protein levels of metalloproteinase-9 (MMP-9) or nm23-H1 upon LMPAB treatment were detected by
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Chai, Yuxia, Jizhong Xu, and Baojun Yan. "The anti-metastatic effect of baicalein on colorectal cancer." Oncology Reports 37, no. 4 (2017): 2317–23. http://dx.doi.org/10.3892/or.2017.5437.

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Han, Yo-Han, Jeong-Geon Mun, Hee Dong Jeon, Ji-Ye Kee, and Seung-Heon Hong. "Betulin Inhibits Lung Metastasis by Inducing Cell Cycle Arrest, Autophagy, and Apoptosis of Metastatic Colorectal Cancer Cells." Nutrients 12, no. 1 (2019): 66. http://dx.doi.org/10.3390/nu12010066.

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Background: Colorectal cancer (CRC) is one of the diseases with high prevalence and mortality worldwide. In particular, metastatic CRC shows low probability of surgery and lacks proper treatment. In this study, we conducted experiments to investigate the inhibitory effect of betulin against metastatic CRC and related mechanisms. Methods: Water-soluble tetrazolium assay was used to determine the effect of betulin on metastatic CRC cell viability. Flow cytometry and TUNEL assay were performed to confirm whether betulin can induce apoptosis, autophagy, and cell cycle arrest. A lung metastasis mou
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Tamaki, T., M. Iwakawa, T. Ohno, et al. "Anti-Metastatic Effect of Local Carbon-Ion Irradiation in a Highly Metastatic Mouse Model." International Journal of Radiation Oncology*Biology*Physics 69, no. 3 (2007): S613. http://dx.doi.org/10.1016/j.ijrobp.2007.07.1927.

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Tanriover, Gamze, Sayra Dilmac, and Nuray Erin. "Melatonin Does Not Alter Cell Proliferation in Metastatic Breast Cancer Cells." Proceedings 2, no. 25 (2018): 1567. http://dx.doi.org/10.3390/proceedings2251567.

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Breast cancer treatments continue to be investigated with supported by new treatment methods. Melatonin is a hormone that can be effective in the treatment of breast cancer due to its anti-oxidant effect. Melatonin had previously shown to inhibit proliferation of cancer cells. In this study, we aimed to determine the effect of melatonin on the proliferation of metastatic breast cancer cells in comparison to doxorubicin, a well-known chemotherapeutic agent. Doxorubicin inhibited proliferation of metastatic breast cancer cells while melatonin has no effect. We are currently examining the effects
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De, Debapriya, Priyanka Chowdhury, Sujogya Kumar Panda та Utpal Ghosh. "Leaf Extract and Active Fractions of Dillenia pentagyna Roxb. Reduce In Vitro Human Cancer Cell Migration Via NF-κB Pathway". Integrative Cancer Therapies 21 (січень 2022): 153473542211288. http://dx.doi.org/10.1177/15347354221128832.

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Background: Different parts of Dillenia pentagyna have long been used in traditional medicines to cure several diseases including cancer. However, the mechanism(s) of anti-cancer effects are still unknown. We aimed to elucidate the anti-metastatic potential of ethanolic extracts of leaves of D. pentagyna (EELDP) and active fractions of it in highly metastatic human cancer cells. Methods: We screened different HPLC fractions of EELDP based on their anti-metastatic effect. We used TLC and ESI-MS for determining the presence of various phytochemicals in EELDP and fractions. We monitored in vitro
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Karsch-Bluman, Adi, Shimrit Avraham, Miri Assayag, Ouri Schwob, and Ofra Benny. "Encapsulated Carbenoxolone Reduces Lung Metastases." Cancers 11, no. 9 (2019): 1383. http://dx.doi.org/10.3390/cancers11091383.

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Carbenoxolone is an anti-inflammatory compound and a derivate of a natural substance from the licorice plant. We previously showed that carbenoxolone reduces the metastatic burden in the lungs of mice through its antagonistic effect on high mobility group box 1 (HMGB1). To further enhance carbenoxolone’s activity and localization in the lungs, thereby reducing the potential adverse side effects resulting from systemic exposure, we developed a poly(lactic-co-glycolic acid) (PLGA) slow-release system for pulmonary delivery which maintains drug activity in-vitro, as demonstrated in the anoikis as
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Muflikhasari, Haruma Anggraini, Riris Istighfari Jenie, Ratna Asmah Susidarti, and Edy Meiyanto. "Growth Inhibitory Property of Pentagamavunone-0 (PGV-0) on 4T1 Cells under Stress Condition : 2D and 3D Culture Model." Indonesian Journal of Cancer Chemoprevention 10, no. 3 (2019): 149. http://dx.doi.org/10.14499/indonesianjcanchemoprev10iss3pp149-158.

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Pentagamavunone-0 (PGV-0), one of the curcumin analogue, is reported to have a cytotoxic effect on various cancer cells. This study aimed to explore the growth inhibitory effects of PGV-0 against highly-metastatic breast cancer, 4T1 cells under stress condition covering 2D and 3D speroid cytotoxic, anti-migration, and suppression of MMP-9. PGV-0 showed cytotoxic effects on 2D and 3D 4T1 cells with IC50value of 49 μM and 26 μM, respectively. In addition, PGV-0 performed anti-migratory effect. The single treatment at 25 μM PGV-0 and 50 μM showed inhibitory effect on cell migration by 54% and 51%
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Dissertations / Theses on the topic "Anti-metastatic effect"

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Elkashef, Sara M. "Pharmacological evaluation of novel polysialyltransferase inhibitors as anti-metastatic agents and development of analytical methods for assessment of polysialylation inhibition : in vitro assessment of the effects of novel polysialyltransferase inhibitors on tumour cell function and development of quantitative HPLC-based methods for evaluation of novel polysialyltransferase inhibitors." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/14123.

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Polysialic acid (polySia) is a carbohydrate polymer highly expressed during embryonic development but rarely expressed during postnatal development. Two polysialyltransferase (polyST) enzymes are responsible for the synthesis of polySia: ST8SiaII and ST8SiaIV. During oncogenesis polySia is re-expressed and it modulates cell-cell and cell-matrix adhesion, migration, invasion and metastasis. PolySia expression is strongly associated with poor clinical prognosis and correlates with aggressive and invasive disease in neuroblastoma and many other tumours. PolyST inhibition thus presents a novel, se
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Shiao, Cheng-Kai, and 蕭承愷. "The Anti-metastatic Effect of Glabridin in NCI-H460 Lung Cancer Cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/52687014841490844293.

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碩士<br>中華醫事科技大學<br>生物科技系暨生物醫學研究所<br>103<br>Glabridin, isolated from Glycyrrhiza uralensis Linn., is a naturally occurring flavonoids in licorice. Some reports demonstrated that glabridin had various anti-carcinogenic properties. First, the result demonstrated glabridin could inhibit the abilities of the adhesion, invasion, and migration by cell-matrix adhesion assay, Boyden chamber invasion/migration assay, and wound healing assay. Data also showed glabridin could inhibit the enzyme activities and messenger RNA levels of matrix metalloproteinase-2/9 (MMP-2/MMP-9) and u-PA by gelatin zymography
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Huang, Sheng-Kai, and 黃聖凱. "Anti-metastatic effect of acridone alkaloids from twigs of Severinia buxifolia in NSCLC." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/j7eah7.

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碩士<br>高雄醫學大學<br>天然藥物研究所碩士班<br>106<br>Lung cancer is one of the most common cancer worldwide which is by far the leading cause of cancer death because of its rapid metastasis and poor prognosis. The incidence of lung cancer about 80% diagnosed with non-small lung cancer (NSCLC). Therefore, developing novel anti-cancer drugs to treat with NSCLC is indispensable. Serverinia buxifolia, a common folk medicine used in Southeast Asia, which displays many pharmacological activities such as anti-malaria, anti-rheumatism, and anti-nociceptive. Acridone alkaloids [atalaphyllidine (Sbs-A), atalaphyllinine
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Wang, Ya-Ling, and 翁雅玲. "Anti-metastatic effect achieved by oral administration of resveratrol on BALB/c mice challenged with CT26 tumor cells." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/27605823301766634752.

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碩士<br>國立嘉義大學<br>食品科學系研究所<br>95<br>Multiple bioactivities of resveratrol such as prevention of cardiovascular disease, anti-cancer and extension of lifespan have been demonstrated. Among its anti-cancer activities, anti-metastasis has been meagerly studied. In this study, pulmonary metastasis of BALB/c mice challenged with CT26 of colorectal adenocarcinoma cells as affected by oral administration with different doses of resveratrol was examined. Tail intravenous injection with CT26 cells was conducted. The oral administration doses included low dose group (5 mg/kg/day, n=10), middle dose group
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Chen, Ching-Chun, and 陳靜君. "Hibiscus sabdariffa Polyphenol-rich extract (HPE) via regulate CD44 signal pathway to anti-metastatic effect on human colon cancer." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/13398182322361961282.

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碩士<br>中山醫學大學<br>生化暨生物科技研究所<br>101<br>In recent years, a natural plant extract an effective ingredient, thereby preventing or inhibiting the occurrence of cancer research has been the current trend. Roselle polyphenols Hibiscus sabdariffa Polyphenol-rich extract (HPE), one of the component in Roselle’s function, our previous studies indicate that HPE can effectively promote apoptosis on gastric cancer and colon cancer cell, the impact on tumor metastasis has not been clarified, so the next one probe into whether HPE inhibit cancer cell metastasis, and to explore the mechanism. We conducted MTT
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Xia, Ci-Chan, and 夏慈禪. "The Anti-metastatic Effects of Inoscavin A on Lung Cancer Cell Lines." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/62qze4.

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碩士<br>中國醫藥大學<br>中國藥學暨中藥資源學系碩士班<br>102<br>Lung cancer is the leading cause of cancer mortality, and metastasis is a primary cause of cancer death. Inoscavin A is a new compound isolated from a medicinal mushroom Inonotus sanghuang. In this study, we first observed that inoscavin A exerted a dose-dependent inhibitory effect on adhesion, migration, and invasion of the highly metastatic A549 and LLC lung cancer cell lines in the absence of cytotoxicity. These effects were associated with a decreased protein expression of MMP-2 and MMP-9 together with an increased expression of TIMP-1 and PAI-1. In
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Yen, Chih-Yung, and 嚴智勇. "The anti-metastatic effects of Ellagic acid in Human lung carcinoma A549 cells." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/10515450764665479813.

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碩士<br>中國醫藥大學<br>中國藥學暨中藥資源學系碩士班<br>99<br>Metastasis in cancer patients is often fatal cancer caused by one of the reasons. Metastasis of cancer cells involve multiple processes and various cytophysiological changes, including changing adhesion capability between cells and extracellular matrix (ECM) and damaging intercellular interaction. Degradation of the ECM of the basement membrane was caused by proteinases such as matrix metalloproteinases (MMPs). Among the MMPs family, MMP-2 and MMP-9 play a critical role in tumor invasion and metastasis, therefore, the inhibition of cell migration or inva
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Cheng-Chi, Yang, and 楊呈琦. "To study the anti-metastatic effects of clarithromycin on non-small lung cancer cells." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/84901574780516346840.

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碩士<br>國立中興大學<br>生命科學系<br>93<br>Abstract Clarithromycin is a new 14-member macrolide antibiotic, it has been used as anti-inflammatory drug to treat diffuse panbronchiolitis and to restraining Helicobacter Pylori since 1990. Clinically mainly in long term-low dose; in 1997, Yasunami indicated that clarithromycin is a potent angiogenesis inhibitor for anti-tumor activity, the research later indicated clarithromycin can suppress tumor-associated growth factor expression by tumor, such as TNF-α and IL-6, result in suppressed tumor growth and metastasis, but its detail mechanism is unclear. And i
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Chen, Yu-Ling, and 陳玉聆. "Effects on Cell Growth and Expression of Anti-metastatic Gene Drg 1 by Apigenin and Butyrate in Human Metastatic Colorectal Carcinoma Cell LoVo." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/14760677857910965608.

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碩士<br>實踐大學<br>食品營養研究所<br>92<br>Apigenin, a common plant flavonoid, has been reported as a chemopreventive agent possesses anti-oxidative and anti-carcinogenic properties. Butyrate, a short-chain fatty acid produced by microbial fermentation of fiber in the colonic lumen, has been shown to modulate proliferation and differentiation of colon cancer cell line. Drg 1 was first identified upon induction of differentiation in colon carcinoma cells. Recent studies hypothesize that drg 1 might act as a metastatic suppressor gene in colon carcinoma cell line. Based on above hypothesis, the aim of our s
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wang, Hsiao-Chieh, and 王曉潔. "In vitro anti-metastatic effects of hispolon on liver cancer cell line, SK-Hep-1 cell." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/08352912796774236036.

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碩士<br>中國醫藥大學<br>中國藥學研究所<br>96<br>Metastasis is one of the major causes of cancer-associated mortality, and a large number of cancerous cells have the ability to secret matrix metalloproteinases (MMPs). Among them, MMP 2 and MMP 9, an extracellular matrix enzyme, is a key enzyme for cancerous cells to invade distant tissue from in-situ tissue. Many literatures showed that Phellinus linteus (PI) inhibited the cancer proliferation and metastasis. Hispolon was a highly antioxidant compound in PI and it possessed the effect of apoptosis on human epidermoid KB cells. However, the mechanism is still
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Book chapters on the topic "Anti-metastatic effect"

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Hollander, Nurit. "The Immunotherapeutic Effect of Anti Lyt-1 Antibodies on Local and Metastatic Tumor Growth." In Microenvironments in the Lymphoid System. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2463-8_99.

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Lapis, Károly, József Timár, Katalin Pál, András Jeney, Ferenc Timár, and László Kopper. "Membrane Properties of Lewis Lung Tumor Cells with “Low” and “High” Metastatic Capacity: Anti-Metastatic Effect of a Glycosaminoglycan Biosynthesis Blocking Agent 5-Hexyl-2′-Deoxyuridine (HUdR)." In Cancer Biology and Therapeutics. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4757-9564-6_5.

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Akalin, Mustafa Kaan, and Eyyup Sabri Pelit. "Apalutamide Therapy for Metastatic Prostate Cancer." In Current Management of Metastatic Prostate Cancer. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359142.9.

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In this section, apalutamide and androgen Deprivation Therapy (ADT) are recommended for the treatment of hormone-sensitive metastatic prostate cancer (mHSPC). Apalutamide, as a second-generation androgen receptor inhibitor, extends progression-free survival and overall survival when used in combination with ADT. Clinical trials have demonstrated that the combination of apalutamide and ADT is more effective and better tolerated compared to ADT alone. As an innovative non-steroidal anti-androgen, apalutamide exhibits higher affinity to the androgen receptor and prevents androgen receptor translo
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Amirkhosravi, Ali, Shaker A. Mousa, Mildred Amaya, et al. "Assessment of Anti-Metastatic Effects of Anticoagulant and Antiplatelet Agents Using Animal Models of Experimental Lung Metastasis." In Anticoagulants, Antiplatelets, and Thrombolytics. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-803-4_10.

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Brix, Nikko, and Kirsten Lauber. "Immune Checkpoint Inhibition and Radiotherapy in Head and Neck Squamous Cell Carcinoma: Synergisms and Resistance Mechanisms." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-23175-9_2.

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AbstractImmune checkpoint inhibition has emerged as an integral part of the standard-of-care for head and neck squamous cell carcinoma (HNSCC) in recurrent and/or metastatic stages. Clinical responses are impressive but remain limited to a minority of patients. Primary resistance of never-responders is considered to derive from host- and tumor-specific characteristics, the latter comprising tumor immune checkpoint activity, immune contexture, tumor mutational burden, neo-antigen load, and others. Secondary resistance of initially responding patients in addition, appears to be driven predominan
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Mishra, Vartika, Priyanka Yadav, Aprajita Tiwari Pandey, and Tiwari Pandey. "Anti-proliferative, Anti-angiogenic, Anti-apoptotic, and Anti-metastatic Effects of Mushroom." In Mushrooms: A Wealth of Nutraceuticals and An Agent of Bioremediation. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815080568123010006.

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Cancer is the second leading cause of mortality globally after cardiovascular diseases. It is attributed to various genetic and epigenetic changes in the genome, while lifestyle and environmental factors have a say in its rate of progression. Conventional agents like chemotherapy, radiotherapy, and surgical interventions though successful to some extent, are always associated with toxic side effects. A promising alternative could be herbs that form a part of our daily consumption. Mushrooms consumed worldwide have been found to be a treasure of macromolecules like β-glucan, α-glucan, resveratr
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Chauhdary, Zunera, Muhammad Ajmal Shah, Malik Hassan Mehmood, et al. "Saponins in the Treatment of Gastrointestinal Tract Cancer." In Phytonutrients in the Treatment of Gastrointestinal Cancer. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815049633123010010.

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The natural glycosides with triterpenoid or spirostaneaglycones are the saponins, which are associated with a wide range of therapeutic activities, inclusive of gastrointestinal anticancer activities. To promote research and development of novel cytotoxic agents against GIT cancer, this chapter focused on the anticancer potentia l of the naturally occurring triterpenoid and steroidal saponins. The in vitro assays and in vivo studies authenticated the anticancer potential of these compounds through anti-angiogenic, anti-proliferative, anti-metastatic and anti-multidrug resistance activities. Th
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Medhi, Jinu, and Mohan Chandra Kalita. "Nut Phytonutrients for Healthy Gut: Prebiotic Potential." In Nuts and Nut Products in Human Health and Nutrition [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94864.

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Nuts are a combination of prebiotic fiber and phytonutrients and have antioxidant, anti-inflammatory effects. According to 2005 “My Pyramid” it has been grouped with the meat and bean group. Bioactive compounds of nuts such as resveratrol, phytosterols, phenolic acids, flavonoids, and carotenoids display synergistic effects on preventing many age related pathologies. Resveratrol has been reported to extend the lifespan in model organisms such as yeast, Drosophila and mouse. Reports propose nuts as the best substitute for red meat to reduce mortality risk. Macadamia nuts with a rich source of m
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Singh, Ashutosh, Ravinsh Kumar, and Amrita Srivastava. "2-Deoxy-D-Glucose as an Emerging Chemotherapeutic Agent in Cancer Management." In 2-Deoxy-D-Glucose: Chemistry and Biology. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815305159124010012.

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Cancer cells have a unique property of uncontrolled growth and thus they require a constant supply of energy. Warburg observed that tumor cells prefer glycolysis even under oxygenic conditions and the process is known as aerobic glycolysis. Hence, cancerous cells show an enhanced glucose-to-lactate conversion rate. As cancerous growth is accompanied by enhanced glucose uptake, this feature is best suited for the management of unwanted cell proliferation by blocking the glucose metabolism of cancer cells. 2-deoxy-D-glucose (2DG), a glucose antimetabolite is considered a competitive inhibitor of
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Vikas, Biba, Vishnupriya K. Sweety, Sukumaran Anil, and Senthilnathan Palaniyandi. "Natural Anticarcinogens: The Efficacy of Herbs and Spices." In Herbs and Spices - New Perspectives in Human Health and Food Industry [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1004335.

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This chapter comprehensively reviews numerous herbs and spices’ anticancer properties and mechanisms. Curcumin, derived from turmeric, exhibits cytotoxic, anti-proliferative, anti-invasive, and anti-metastatic effects against diverse cancer types by interacting with pathways controlling inflammation, survival, cell cycle, apoptosis, and angiogenesis. Ginger and its active compounds demonstrate antioxidant, anti-inflammatory, and anti-tumor activities in breast, skin, lung, and gastrointestinal cancer models, potentially through free radical scavenging, inhibiting inflammation, disrupting micro
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Conference papers on the topic "Anti-metastatic effect"

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Adelaiye-Ogala, Remi M., Li Shen, Sreenivasulu Chintala, et al. "Abstract 4132: Anti-tumor and anti-metastatic effect of sunitinib in a patient derived metastatic clear cell renal cell carcinoma xenograft model." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4132.

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Alkahlout, Amal Shahada, Ali Eid, Ipek Goktepe, and Alaeldin Saleh. "Anti-proliferative and Anti-metastatic Effect of Aqueous Extract of Origanum Syriacum on Aggressive Human Breast Cancer Cells." In Qatar Foundation Annual Research Conference Proceedings. Hamad bin Khalifa University Press (HBKU Press), 2016. http://dx.doi.org/10.5339/qfarc.2016.hbsp2124.

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Lim, Yoojoo, Sae-Won Han, Jeong Hee Yoon, et al. "Abstract A2: Clinical implications of anti-angiogenic effect of regorafenib in metastatic colorectal cancer." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-a2.

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Šuráňová, Markéta, Daniel Zicha, Pavel Veselý, Jan Brábek, Veronika Jůzová, and Radim Chmelík. "In Vitro Screening with Holographic Incoherent Quantitative Phase Imaging Focuses on Finding Medicaments for Repurposing as Anti-Metastatic Agents Designated as Migrastatics." In European Conference on Biomedical Optics. Optica Publishing Group, 2021. http://dx.doi.org/10.1364/ecbo.2021.em1a.38.

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Live lung cancer cells in vitro were exposed to selected medicaments with putative anti- metastatic potential and examined by time-lapse hiQPI, providing simultaneous measurements of the effect on cell growth and motility with unprecedented accuracy.
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Malinovskaya, Yulia, Svetlana Gelperina, Olga Maksimenko, and Vladimir Baklaushev. "Considerable Anti-tumour Effect of Nanoparticle-Bound Doxorubicin against 4T1 Metastatic Breast Cancer in Mice." In The 2nd World Congress on Recent Advances in Nanotechnology. Avestia Publishing, 2017. http://dx.doi.org/10.11159/nddte17.108.

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Gonzalez, Addys, Rances Blanco, Adriana Carr, and Kalet Leon. "Abstract B120: Synergistic potentiation of the anti-metastatic effect of anti EGFR mAbs by its combination with immunotherapies targeting the ganglioside NGcGM3." In Abstracts: Second CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 25-28, 2016; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6066.imm2016-b120.

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Liu, Ping, Xiaomin Ren, and Lisa X. Xu. "Alternate Cooling and Heating Thermal Physical Treatment: An Effective Strategy Against MDSCs in 4T1 Mouse Mammary Carcinoma." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80229.

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An alternate thermal physical treatment was developed to destroy tumor tissue using liquid nitrogen cooling and RF heating treatment in our pervious study. Our pervious reports had shown that anti-tumor immunity was induced by the alternate treatment. Myeloid derived suppressor cells (MDSCs) are a subset of heterogeneous, bone marrow derived hematopoietic cells that accumulate in the spleen, bone marrow, blood and tumor sites of tumor-bearing mice and cancer patients. MDSCs are one of the key suppressor cells that regulate anti-tumor immune responses in tumor-bearing hosts. MDSCs have been sho
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Fung, Leah, Laura G. Corral, Robert W. Sullivan, Kyle W. Chan, and Cathy A. Swindlehurst. "Abstract LB-211: Synergistic anti-metastatic effect of pembrolizumab in combination with a novel mTORC1 inhibitor/AMPK agonist in a CAM metastatic triple negative breast cancer model." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-lb-211.

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Lu, Yen-Shen, Bang-Bin Chen, Ching-Hung Lin, et al. "Abstract 2984: Normalization of tumor vasculature by anti-angiogenesis therapy in metastatic tumor: A clinical study to determine the timing and effect." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2984.

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KIM, GUEN TAE, SUN YOUNG YOON, KI-YOUNG SOHN, MYUNG-HWAN KIM, and JAE WHA KIM. "Abstract C037: Anti-metastatic effect of PLAG via interference of neutrophil elastase/PAR2/EGFR signaling on A549 lung cancer orthotopic implantation model." In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c037.

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Reports on the topic "Anti-metastatic effect"

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Sritularak, Boonchoo, Kittisak Likhitwitayawuid, Pithi Chanvorachote, and Varisa Pongrakhananon. Cytotoxic constituents from Dendrobium spp. : Final report. Chulalongkorn University, 2014. https://doi.org/10.58837/chula.res.2014.28.

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The MeOH extracts of Dendrobium pullchellum Roxb. Ex Lind1. And D. ellipsophyllum Tang &amp; wang (Orchidaceae) showed significant cytotoxic activity against human lung cancer cells. Phytochemical study of the whole plant of D. pullchellum Roxb. Ex Lind1 led to the isolation of seven phenolic compounds, namely, chrysotobibenzyl, chrysotoxine, crepidatin, moscatilin, fimbriatone, (-) –shikimic acid and liriodendrin. The whole plant of D. ellipsophyllum Tang &amp; wang yielded ten phenolic compounds indluding moscatilin, 5,7-dihydroxy-chromen-4-one, 4,5-dihydroxy-2,3-dimethoxy-9,10-dihydrophenan
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