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Dissertations / Theses on the topic 'Anti-Müllerian hormone'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Johnson, Justin M. "Characterization of the Immune Response to Anti-Müllerian Hormone." Cleveland State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=csu1606840042907281.

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2

Koskela, S. (Sanna). "Granulosa cell anti-Müllerian hormone secretion in ovarian development and disease." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526202853.

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Abstract Anti-Müllerian hormone (AMH) was identified originally in connection with its role in male sexual differentiation. In females, AMH is secreted by ovarian granulosa cells of growing follicles and its serum levels correlate well with the remaining number of follicles, thus reflecting ovarian reserve. The aim of this study was to explore the expression and secretion of AMH in human ovarian development and in various disorders resulting in decreased reproductive function. In fetal ovaries, AMH expression was found to be initiated at midgestation and it increased gradually towards term. In

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3

Rustamov, Oybek. "The role of anti-Müllerian hormone in assisted reproduction in women." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-antimullerian-hormone-in-assisted-reproduction-in-women(4ea8be56-0eeb-4687-9d48-cb7e0f599287).html.

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Anti-Müllerian hormone appears to play central role in regulation of oocyte recruitment and folliculogenesis. Serum AMH concentration was found to be one of the best predictors of ovarian performance in IVF treatment. Consequently many fertility centres have introduced AMH for the assessment of ovarian reserve and as a tool for formulation of ovarian stimulation strategies in IVF. However published evidence on reliability of AMH assay methods and the role of AMH-tailored individualisation of ovarian stimulation in IVF appear to be weak. Consequently, I decided to conduct a series of studies th

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4

Claes, Anthony N. J. "ANTI-MÜLLERIAN HORMONE IN STALLIONS AND MARES: PHYSIOLOGICAL VARIATIONS, CLINICAL APPLICATIONS, AND MOLECULAR ASPECTS." UKnowledge, 2014. http://uknowledge.uky.edu/gluck_etds/18.

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Anti-Müllerian hormone (AMH) is a homodimeric glycoprotein that is best known for its role in regression of the Müllerian duct in the male fetus. Accumulating evidence indicates that AMH also has an important role during different physiological processes after birth. In contrast to other species, relatively little is known about AMH in the horse. In chapter one, developmental and seasonal changes in serum AMH concentrations in male horses were determined, and the use of AMH for determination of retained cryptorchid testes was established. In chapter two, the interrelationship between plasma AM

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5

Elfituri, Abdullatif. "Investigating the regulatory role of Anti-Müllerian Hormone in the growing follicles of a monovulatory species." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/33570/.

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Evidence from recent research suggests that folliculogenesis is regulated by stage specific locally produced growth factors and hormones including mediators of proliferation, differentiation and angiogenesis. AMH has been identified as one of these potentially important local factors and in polyovulatory species has been implicated in the regulation of the follicles growth, throughout its developmental stages. However in monovulatory species, despite its circulating levels being use as a marker of ovarian reserve and its suggested link to the aetiology of PCOS, little is known about its role a

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6

Mimouni, Nour El Houda. "Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome (PCOS) in adulthood." Thesis, Lille, 2019. http://www.theses.fr/2019LILUS051.

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Le syndrome des ovaires polykystiques (SOPK) est la principale cause d’infertilité feminine à travers le monde, associé à un risqué élevé de comorbidités avec des conséquences économiques non négligeables. Ce syndrome est caractérisé par une oligo-anovulation, une hyperandrogénie, et un aspect échographique d’ovaires polykystiques. De plus, la plupart des femmes atteintes de SOPK présentent des concentrations élevées de LH suggérant une libération accrue de GnRH. De plus, les patientes SOPK ont habituellement des concentrations en Hormone Anti Müllerienne (AMH) 2 à 3 fois plus élevés que les f

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7

Trombley, Susanne. "Gene expression of the gonadotropin receptors and anti-Müllerian hormone in early maturing male Atlantic salmon parr, Salmo salar." Thesis, Karlstads universitet, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-3232.

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An up-regulation of gene expression of the gonadotropin receptors FSHR and LHR, and a down-regulation of anti-Müllerian hormone (AMH), in the gonads of early maturing male Atlantic salmon parr (Salmo salar) have been shown to take place during the process of sexual maturation. It has however not been determined if this happens prior to or after the onset of spermatogenesis. The aim of this study was to see if such an up-regulation of the gene expression of FSHR and LHR mRNA, and down-regulation of AMH in the gonad tissue could be seen prior to the onset of spermatogenesis in early maturing sal

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8

Gasparin, Andrese Aline. "Avaliação da reserva ovariana em mulheres pré- menopáusicas portadoras de lúpus eritematoso sistêmico." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/115003.

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Objetivos: A reserva ovariana de pacientes com lúpus eritematoso sistêmico (LES) pode ser afetada pela atividade de doença e pelo tratamento medicamentoso. Estudos realizados até o momento mostram que pacientes com LES têm taxas de fertilidade semelhantes às de mulheres hígidas da mesma idade. Este trabalho tem como objetivo estudar a reserva ovariana de pacientes com LES e compará-la com a de controles saudáveis através da dosagem do hormônio anti-Mülleriano (HAM). Métodos: Estudo de caso-controle no qual foram incluídas 80 mulheres prémenopáusicas, sendo 40 pacientes com diagnóstico de LES s

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9

Sèdes, Lauriane. "Voie de signalisation et gènes cibles de l’AMH dans le tractus génital femelle." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T014/document.

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L’hormone anti-Müllerienne (AMH) est un membre de la famille TGF-β impliquée dans la différenciation du tractus reproductif mâle. Elle est aussi exprimée par les cellules de la granulosa de l’ovaire adulte. Cependant, son rôle physiologique chez la femelle n’a pas encore été entièrement établi. Mon projet de thèse a pour objectif d’élucider le(s) rôle(s) de l’AMH dans le tractus reproductif femelle. L’AMH transduit ses effets par l’intermédiaire de deux récepteurs transmembranaires sérine/thréonine kinase : un récepteur de type II qui lui est spécifique (AMHR-II) et un récepteur de type I (Act

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10

Renzi, Adriana. "Análise da influência do hormônio anti-Mülleriano na produção in vitro de embriões bovinos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/17/17135/tde-19042013-154338/.

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A maturação in vitro de oócitos (MIV) é uma importante tecnologia reprodutiva a qual gera oócitos maduros capazes de suportar o desenvolvimento embrionário pré-implantacional e sua completa evolução à termo. Muitos fatores levam ao processo de maturação do oócito, e o AMH (hormônio anti-Mülleriano) tem demonstrado possuir um importante efeito nesta etapa. Neste trabalho nós demonstramos a influência da suplementação de AMH na maturação de complexos cumulus-oócito (COCs). Nossos resultados demonstram que não houve efeito na produção de embriões para COCS grau I. Entretanto, pudemos encontrar di

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11

Fagundes, Paulo Augusto Peres. "Avaliação da ecografia 3D (SonoAvc) para contagem de folículos antrais em mulheres inférteis : sua correlação com ecografia convencional 2D e com os níveis séricos do hormônio anti-Mülleriano." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/132110.

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Introdução: A contagem de folículos antrais (AFC) tornou-se uma ferramenta importante na avaliação da reserva ovariana. Vários estudos têm demonstrado uma relação entre a contagem de folículos antrais por ecografia transvaginal 2D e o hormônio anti- Mülleriano. Poucos estudos têm sido feitos estudando o papel da ecografia transvaginal 3D SonoAVC, particularmente em mulheres inférteis. A contagem de folículos na ecografia 2D convencional, como é conhecida, tem limitações como a variabilidade intra e inter-observadores e o tempo gasto no exame no caso de múltiplos folículos. Com a contagem autom

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12

Lima, Maria Lucia dos Santos. "Relação do peso ao nascer com a concentração sérica do hormônio antimulleriano: estudo transversal aninhado a uma coorte de mulheres na menacme." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17145/tde-29082016-113736/.

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Introdução: O processo de envelhecimento reprodutivo ocorre em virtude do declínio progressivo na quantidade e qualidade de óvulos que se inicia após a puberdade, se mantém ao longo da menacme, com redução gradual da fertilidade, e termina na menopausa, caracterizada pelo esgotamento do número de folículos e, consequentemente, da reserva ovariana funcional (ROF). A vida pré-natal constitui um importante período para o desenvolvimento dos órgãos genitais internos femininos e mudanças nessa fase podem ter repercussões futuras: quando o feto é submetido a condições adversas intrauterinas, mecanis

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13

Martínez, Pinto Jonathan Eloy. "Neonatal exposure to estradiol reprograms the expression of androgen receptor and anti-müllerian hormone [recurso electrónico]: short and long term effects and their relation to the polycystic ovary phenotype." Tesis, Universidad de Chile, 2014. http://www.repositorio.uchile.cl/handle/2250/116937.

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Doctor en Bioquímica<br>Reproduction is regulated through the integration of information that comes from the hypothalamus, hypophysis, and the ovary. There are critical hormone sensitive periods during development during which they are especially vulnerable to exposure to abnormal hormonal levels resulting from metabolic problems or environmental sources. These exposures may permanently alter the differentiation and function of reproductive organs. Several studies performed in humans and animal models have suggested that polycystic ovary syndrome (PCOS) originates during early development due

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14

Gamarra, Lazo Giselle del Carmen. "Modulation des taux plasmatiques d’insuline par l’apport de propylène glycol dans l’alimentation : effet sur la quantité, la qualité des ovocytes et des embryons produits in vitro chez des génisses laitières." Thesis, Paris, AgroParisTech, 2014. http://www.theses.fr/2014AGPT0083.

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L’Ovum Pick-Up (OPU) et la production d'embryons in vitro représentent une voie d’accélération du progrès génétique par la voie femelle. Ces techniques impliquent en autre la collecte d’ovocytes de qualité pour produire des embryons transférables. La qualité des ovocytes et les taux de développement embryonnaire in vitro sont impactés par la nutrition des donneuses avant OPU, les effets étant médiés par plusieurs métabolites et hormones impliqués dans la régulation du métabolisme énergétique. Les niveaux plasmatiques d'insuline et d’IGF1 accrus sont corrélés aux niveaux des apports énergétique

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15

D'Avila, Ângela Marcon. "Avaliação da reserva ovariana em mulheres com câncer de mama submetidas à quimioterapia." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/76199.

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Introdução: A reserva ovariana (RO) refere-se à quantidade e, para alguns autores, à qualidade de folículos presentes nos ovários em um dado momento. É a medida pela qual se avalia a produção de oócitos e consequente potencial reprodutivo. Ela pode ser inferida mediante dosagem dos níveis séricos do hormônio folículo estimulante (FSH), estradiol, inibina B e hormônio antimülleriano (HAM), e ainda, ultrassonograficamente, através da contagem de folículos antrais (CFA). Na década de 50 observou-se que mulheres submetidas à quimioterapia (QT) apresentavam falência ovariana mais precocemente, efei

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16

Wade, Leslie Schwierzke. "Assessment of Fertility Potential in Bottlenose Dolphins (Tursiops truncatus): An ELISA-based Biomarker Analysis." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3399.

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As apex predators in coastal systems, bottlenose dolphins (Tursiops truncatus) are susceptible to persistent organic pollutant (POP) accumulation and retention over time, which has prompted continued interest in understanding the extent to which contaminant body burdens or other stressors are sufficient to cause adverse sublethal effects on energetic fitness, immune function, or reproduction. Increasing our knowledge of reproductive endocrinology in bottlenose dolphins may provide insight into changes in reproductive rates, thereby expanding the capacity to assess conservation status. This s

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17

Woloszynek, Renata dos Santos Batista Reis. "Validação, valores normativos e aplicabilidade clínica de um ensaio imunoenzimático para determinação sérica do hormônio anti-Mülleriano." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-11082014-120509/.

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O hormônio anti-Mülleriano (AMH) é um marcador de reserva ovariana e função testicular. A aplicação clínica desse hormônio requer padronização adequada de valores de referência, de acordo com o imunoensaio utilizado. Os objetivos deste estudo foram: validar o imunoensaio AMH Gen II (Beckman Coulter Company, TX, USA), estabelecer valores normais de AMH em homens e mulheres saudáveis, avaliar a influência do uso de contraceptivos hormonais, tabagismo e índice de massa corpórea (IMC) sobre os valores de AMH e verificar as concentrações séricas desse hormônio em pacientes com síndrome de Turner (S

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18

Oderich, Carolina Leão. "Síndrome pré-menstrual : relação entre a intensidade dos sintomas e a reserva ovariana." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/164362.

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Introdução. A Síndrome Pré-menstrual (SPM) é caracterizada por sintomas de estresse somáticos e comportamentais que se desenrolam logo após a ovulação, atingindo um pico máximo próximo à data da menstruação e desaparecendo em média em até quatro dias após o início do sangramento. A presença da formação do corpo lúteo seria necessária para a presença dos sintomas, contudo essa dinâmica dos hormônios da fase lútea associados à SPM é pouco conhecida. O hormônio antimülleriano (HAM) é um dos melhores marcadores de declínio da capacidade reprodutiva das mulheres. Até o momento o mesmo não foi corre

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19

Prunskaite-Hyyryläinen, R. (Renata). "Role of Wnt4 signaling in mammalian sex determination, ovariogenesis and female sex duct differentiation." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526204727.

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Abstract Mammalian female sex development was considered a default developmental pathway. However, the deletion of the Wnt4 gene, a member of the Wnt family of secreted signals, was shown to reverse the sex of XX female mouse embryo and caused exhibition of certain male characteristics. This indicated that the female sexual development cannot be default but depends on active signaling and cell-cell interaction. The aim of the current study was to reveal the functional role of the Wnt4 gene in the control of sex determination, ovariogenesis and female sex duct formation. This study demonstrates

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20

Martínez, Pinto Jonathan Eloy [Verfasser], Hernan [Akademischer Betreuer] Lara, and Michael [Akademischer Betreuer] Rehli. "“Neonatal exposure to estradiol reprograms the expression of androgen receptor and anti-Müllerian hormone: short and long term effects and their relation to the polycystic ovary phenotype” / Jonathan Eloy Martínez Pinto. Betreuer: Hernan Lara ; Michael Rehli." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/1083250930/34.

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21

Pan, Qiaowei. "Utiliser ou ne pas utiliser un gène de détermination du sexe : évolution des systèmes de détermination du sexe chez les Esociformes." Thesis, Rennes, Agrocampus Ouest, 2017. http://www.theses.fr/2017NSARB305/document.

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Les téléostes, le clade possédant le plus d’espèces parmi les vertébrés, emploient une saisissante diversité de mécanismes de détermination du sexe, incluant des mécanismes génétiques et environnementaux. Des études récentes ont identifié de nombreux nouveaux régulateurs génétiquesdu développement sexual des poissons et ont introduit la notion de “terrain de jeux évolutif”. Le but de ce projet de thèse est de donner une vue complète des dynamiques évolutives des déterminants du sexe dans un ordre de téléostes, les Esociformes. Dans notre espèce focale, Esox lucius, nous avons identifié une dup

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22

Brodin, Thomas. "Ovarian Reserve and Assisted Reproduction." Doctoral thesis, Uppsala universitet, Obstetrik & gynekologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-192998.

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Treatment success in IVF-ICSI is mainly limited by female age, but differences in ovarian reserve (OR; the remaining pool of oocytes and their quality) between individuals modify treatment prerequisites among women of similar age. OR may be assessed by OR tests (ORTs). The main aims of this work were to study menstrual cycle length (MCL), basal levels of circulating gonadotrophins, antral follicle count (AFC) and serum Anti-Müllerian hormone (AMH) levels and their associations with and prognostic capacities regarding IVF-ICSI outcome in large cohorts of unselected women. Age-adjusted MCL was p

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23

Yamakami, Lucas Yugo Shiguehara. "Avaliação da reserva ovariana em pacientes com síndrome antifosfolípide primária." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-18102013-153634/.

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Introdução: A síndrome antifosfolípide é uma doença autoimune caracterizada por eventos trombóticos e/ou obstétricos adversos associados à presença de anticorpos antifosfolípides. Considera-se síndrome antifosfolípide primária (SAFP) quando não há outra doença autoimune ou inflamatória associada. Objetivos: Avaliar marcadores de reserva ovariana em mulheres com SAFP e a associação entre estes marcadores e dados clínicos, laboratoriais e anticorpo anti-corpo lúteo (anti-CoL). Métodos: Realizou-se estudo transversal em 18 pacientes com SAFP e 24 controles. A reserva ovariana foi avaliada na fase

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Hudecova, Miriam. "Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-123248.

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Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. The overall risk of developing type 2 diabetes and impaired glucose tolerance (IGT) is three- to sevenfold higher in PCOS women, and the onset of glucose intolerance seems to occur at an earlier age than in healthy controls. Women with PCOS also have several risk factors for cardiovascular dis

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Ortega, Céline. "Ingénierie de fragments d'anticorps pour l'imagerie in vivo de cancers de la sphère génitale." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00766847.

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Le pronostic de certains cancers s'est considérablement amélioré avec l'arrivée sur le marché des anticorps thérapeutiques. Devant l'essor de ces nouveaux médicaments associé à l'identification de nouveaux biomarqueurs, de nouvelles perspectives émergent pour l'imagerie moléculaire in vivo. En effet, disposer de nouveaux traceurs moléculaires spécifiques de ces biomarqueurs permettra de caractériser l'hétérogénéité des cellules cancéreuses, de suivre l'expression de ces marqueurs au cours de l'évolution de la tumeur, mais également de suivre l'efficacité d'un traitement sur la régression tumor

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Liu, Yen-Chun, and 劉彥均. "Cloning, characterization and functions of the zebrafish （Danio rerio） anti-Müllerian hormone promoter." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/66089847970599618476.

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碩士<br>國立宜蘭大學<br>生物技術研究所碩士班<br>96<br>Anti-Müllerian hormone genomic DNA sequence was cloned from the zebrafish genomic DNA library. In order to examine the amh promoter activity in vitro and in vivo, amh promoter regions to luciferase or enhanced green fluorescent protein (EGFP) expression vector were constructed. Preliminary analysis of amh promoter indicated that the luciferase activity increased with extended length of promoter region between the -4268~ -488 bp in vitro. A further analysis showed a high relative luciferase activity in the –4268~-2485 bp segment. We therefore speculate that s

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Lan, Kuo Chung, and 藍國忠. "Analysis of androgen receptor and anti-Müllerian hormone pathways in human granulosa cells and sertoli cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/r39u73.

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博士<br>長庚大學<br>臨床醫學研究所<br>102<br>The first objective was to postulate that up-regulation of SOX9 mRNA and protein due to impairment of androgen/AR signaling in Sertoli cells might explain why high level of anti-Mullerian hormone (AMH) expression occur in these testiculopathic patients. The another objective of this study was to determine the gene expression profiles of the androgen/androgen receptor (AR) and anti-Müllerian hormone (AMH)/ Sry-related high-mobility group box 9 (SOX9) pathways in granulosa-luteal cells from patients undergoing standard in vitro fertilization (IVF) with or without

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Reis, Joana Maria Figueiredo Oliveira. "Polimorfismo do Gene do Receptor da Hormona Folículo-estimulante e Resposta à Estimulação Ovárica." Master's thesis, 2017. http://hdl.handle.net/10316/82498.

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Trabalho de Projeto do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: A resposta ovárica à terapêutica com FSH recombinante exibe uma grande variabilidade individual, pelo que os genes relacionados com o mecanismo de ação da FSH têm sido amplamente estudados. Neste estudo, investigamos a associação entre o polimorfismo Asn680Ser do FSHR e a resposta ovárica de mulheres submetidas a técnicas de RMA. Material e Métodos: Este estudo retrospetivo incluiu 563 mulheres inférteis, com idade inferior a 40 anos e com uma concentração sérica de FSH no 3º dia de um cicl

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Lyu, Ying-Syuan, and 呂盈萱. "The Possible Roles of Anti-Müllerian Hormone and Follistatin in Sex Differentiation and Sex Change in Protandrous Black Porgy（Acanthopagrus schlegeli）." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/07553686592667970227.

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碩士<br>國立臺灣海洋大學<br>水產養殖學系<br>95<br>There are many unknown mechanisms of sex differentiation and sex change in fish. Fishes can be separated into two types of sex differentiation, one is gonochorism and the other is hermaphroditism. Hermaphroditism also can be separated into protogyny and protandry, and black porgy (Acanthipagrus schlegeli) is belonged to protandry. Black porgy will differentiate to functional male in the first and second year after hatching, and some males will change to females in the third year. The objectives were to study the possible roles of anti-Müllerian hormone (Amh) a

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Reis, Mariana Freitas. "Fertility assessment and counselling: does it change the reproductive perspectives of young women?" Master's thesis, 2019. http://hdl.handle.net/10316/89643.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: Adiar a maternidade tem sido uma tendência crescente, razão pela qual se tem demonstrado a importância de providenciar informação personalizada relativamente ao estado da fertilidade individual, permitindo às mulheres tomarem decisões informadas e conscientes relativamente às intenções de parentalidade e planeamento da primeira gravidez.Objetivos: O objetivo deste estudo foi avaliar o potencial reprodutivo duma pequena população de mulheres saudáveis e aconselhá-las de acordo com os resultados,

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Cassar, Samantha. "Polycystic Ovary Syndrome, Obesity and Insulin Resistance." Thesis, 2014. https://vuir.vu.edu.au/30172/.

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Polycystic ovary syndrome (PCOS) is a common and complex reproductive and metabolic condition with major health consequences across the lifespan. Insulin resistance is thought to be a key underlying feature of PCOS, but its role in metabolic and reproductive complications associated with the syndrome remains elusive. Therefore, the aim of the thesis was to comprehensively assess the role of IR in PCOS. I report that IR is definitively intrinsic to PCOS and exacerbated by BMI. But the effect of BMI on IR is more pronounced in PCOS than controls. Diagnostic criteria and age seem to have li

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