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Dissertations / Theses on the topic 'Anti-oxidative effect'

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Published: 2 June 2025

Last updated: 31 July 2025

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1

DIAZ, ANNA RITA. "Valutazione dell'attività biologica e citoprotettiva della ficocianina da Aphanizomenon flos-aquae in colture cellulari miogeniche ed endoteliali esposte a stress ossidativo o stimoli infiammatori." Doctoral thesis, Urbino, 2016. http://hdl.handle.net/11576/2641526.

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Negli ultimi anni i nutraceutici stanno ricevendo sempre più interesse per i loro potenziali effetti terapeutici e nutrizionali. Essi potrebbero avere un ruolo in diversi processi, come nelle risposte antiossidanti ed anti-infiammatorie e nella salvaguardia dell’integrità mitocondriale. Pertanto, i nutraceutici possono essere utilizzati per prevenire delle patologie dove lo stress ossidativo, i meccanismi infiammatori o la perossidazione lipidica giocano un ruolo eziologico. Aphanizomenon flos-aquae (AFA) è una microalga verde-azzurra (cyanophyta) edibile che cresce spontaneamente nel lago Kla

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Li, Ying Bo. "Anti-oxidative and pro-oxidative effects of curcuminoids on cellular senescence in aging and cancer." Thesis, University of Macau, 2011. http://umaclib3.umac.mo/record=b2492795.

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Du, Jing. "Anti-oxidative stress and Anti-inflammatory effects of atorvastatin improve endothelial dysfunction in experimental diabetes Mellitus." [S.l.] : [s.n.], 2005. http://www.diss.fu-berlin.de/2005/147/index.html.

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Diaz, Heredia Zuanel. "Trolox enhances anti-leukemic effects of arsenic trioxide: the role of oxidative stress." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40699.

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Arsenic trioxide (As2O3) has considerable efficacy in the treatment of acute promyelocytic leukemia (APL), inducing partial differentiation and promoting apoptosis of malignant promyelocytes. Although initial studies focused on the role of the characteristic APL fusion protein, PML-RARα, in mediating the response to As2O3, recent investigations indicate that its cytotoxic activities are mediated by mechanisms independent of this fusion protein. As2O3 affects numerous intracellular targets mainly through the accumulation of free radicals and consequent induction of oxidative stress and causes a

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Maslen, Christina Louise. "The effects of anti-inflammatory compounds on the oxidative metabolism of human phagocytic cells." Thesis, University of Bath, 1985. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.353398.

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Phagocytic cells respond to activation by a variety of stimuli by generating oxygen-derived free radicals. The characteristics of the production of superoxide anion and hydrogen peroxide by human neutrophils has been compared with that produced by human monocytes. The majority of work in this thesis is concerned with the employment of an assay which measures hydrogen peroxide produced by stimulated human neutrophils in vitro, but which also has been found to detect the generation of another peroxide, the identity of which is uncertain. The use of cyclooxygenase, lipoxygenase and phospholipase

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Narita, Yusaku. "Studies on the α-Amylase-inhibitory Effects of Chlorogenic Acids from Green Coffee Beans and Anti-oxidative Effects of Coffee Silverskin". Kyoto University, 2013. http://hdl.handle.net/2433/175082.

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Farruggio, Serena. "Direct/indirect protective effects elicited by anti-vascular endothelial growth factor drugs on retinal pigment epithelium cells (ARPE-19 cell line)." Doctoral thesis, Università del Piemonte Orientale, 2019. http://hdl.handle.net/11579/102445.

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The Age-Related Macular Degeneration (AMD) is the leading cause of irreversible loss of vision. In the mechanisms of action of the anti-VEGF agents the involvement of nitric oxide (NO), the mitochondria function and apoptosis have not been examined. In the present study, in order to analyze the cross-talk between retinal pigment epithelium (RPE; ARPE-19) cells and endothelial cells, we conducted co-culture experiments between RPE and human umbilical vascular endothelial cells (HUVEC). RPE and HUVEC/RPE co-culture, were exposed to Ranibizumab/Aflibercept in the absence/presence of NO synthase (

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Potter, Michelle. "Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:6a847ae9-3664-437e-ad26-c1ae3d94f7c0.

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<strong>Background:</strong> Malignant transformation of cells is typically characterised by aerobic glycolysis, resulting in supressed mitochondrial function, a state that helps resistance to apoptosis. This characteristic has been widely accepted as a hallmark of cancer and has been shown to be of critical importance in tumour development. The bioenergetic differences between normal and malignant cells are being exploited to identify potential cancer specific therapeutics. Improved in-vitro models are required to aid the identification and assessment of candidate drugs. In this project, we i

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Chan, Ka-ho John, and 陳家豪. "Effects of Chinese green tea on cigarette smoke-induced oxidative stress, inflammation and proteases/anti-proteases in rat lung in vivo." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45199334.

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The Best PhD Thesis in the Faculties of Architecture, Arts, Business &Economics, Education, Law and Social Sciences (University of HongKong), Li Ka Shing Prize, 2008-2009<br>published_or_final_version<br>Medicine<br>Doctoral<br>Doctor of Philosophy

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Matrose, Albertina Neliswa. "Evaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening models." Thesis, University of the Western Cape, 2014. http://hdl.handle.net/11394/4262.

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Masters of Science<br>The aim of this study was therefore to evaluate the antioxidant and anti-diabesity potential of a hot water extract of C. maculata in non-cell based assays and correlate the activities with phenolic composition. Total antioxidant capacity (TAC) was assessed in terms of free radical scavenging and iron reducing ability. The DPPH, ABTS, ORAC and FRAP assays were employed. Anti-diabesity potential was assessed in terms of the inhibition of the digestive enzymes, α-glucosidase and pancreatic lipase

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Favas, Ana Rita Rodrigues. "Anti-ageing potential of cyanobacteria: effect on matrix metalloproteinases and oxidative stress." Master's thesis, 2021. https://hdl.handle.net/10216/139398.

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Sheng, Hsieh Chun, and 謝俊生. "Oxidative stress mediate the anti-proliferative effect of Anoectochilus formosanus on hepatoma cells." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/77815958189637284833.

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碩士<br>中國醫藥學院<br>醫學研究所<br>90<br>Anoectochilus formosanus is a traditional folk herb that was thought to have effect on liver function protection. Previous studies showed that rat treated with water extracts of A. formosanus had better recovery of liver injury with reduction of the AST and ALT level. To determine the anticancer activity of A. formosanus on hepatocellular carcinoma, HepG2 cells were treated with serial concentration of water extracts of A. formosanus. Significant decrease of HepG2 cell proliferation was found with treatment of A. formosanus at 10 mg/ml. The

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Lin, Hong-Yu, and 林弘育. "The Anti-oxidative/Anti-inflammatory Activities and the Active components of Lotus Leaf Extracts, and its Lipid Modulating/Anti-obesity Effect." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/50082441949473222486.

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博士<br>臺灣大學<br>食品科技研究所<br>98<br>Hypertension and cardiovascular diseases based on atherosclerosis are the leading cause of death in Taiwan. There are many reports about the healthy function of lotus leaf in old Chinese traditional herb book, especially for the function of regulating blood lipid. Therefore, this project aims to conduct bioassay-guided separation and identification of the effective constituents on the anti-oxidative and anti-immflamatory activities, and to understand its functional property. Furthermore, the high fat diet model was used to investigate the blood lipid modulatory e

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Yi, Chen, and 陳怡宏. "The effect of sildenafil analogue on the anti-oxidative enzyme system and sperm quality in rat." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/263677.

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碩士<br>嘉南藥理科技大學<br>保健營養系<br>100<br>Abstract Sildenafil was developed by Pfizer under the name of Viagra, for the treatment of erectile dysfunction (ED). This drug activated NO-cGMP pathway by enhancing the endothelial nitric oxide synthase (eNOS) and inhibiting phosophodiesterase type 5 (PDE5) activities. However, in the presence of superoxide anion (O2-), the NO induced by sildenafil or its analogues will be quickly converted to reactive nitrogen molecules (RNS) causing oxidative stress. NO is a pro-oxidant, however, very little research has done to investigate the effect of sildenaf

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Tsao, Yu-Han, and 曹渝涵. "The effect of L-arginine on the anti-oxidative enzyme system and sperm quality in rat." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/g22249.

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碩士<br>嘉南藥理科技大學<br>保健營養系<br>100<br>L-arginine (L-Arg) is a naturally occurring amino acids involved in many important biochemical reactions in mammalian tissues. The physiological functions of L-Arg , are strongly related to the nitric oxide (NO) concentration in the blood or tissues. NO is a very important cell signaling molecular which is produced from L-Arg by NO synthase. Although , some studies have shown that the additional supplement of L-arg can reduce the oxidative stress in aging rats with acute exercise. However, in the presence of Superoxide anion (O2-), NO will be quickly conve

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Chen, Chang-Wen, and 陳長文. "Effect of Allium tuberosum Seeds Water Extracts on Anti-oxidative Stress and PDE5 Gene Expression in SD Rats." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/22852678615327248568.

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碩士<br>實踐大學<br>食品營養與保健生技學系碩士班<br>99<br>Allium tuberosum seeds (ATS) are dry fruits of Allium tuberosum Rottl. which was a liliacous plant. In recent years, it becomes popular as a health food. In this study, we use 10 time of water, 70% ethanol and butanol, respectively, to extract ATS seeds, and evaluate extraction yield and it was antioxidative activity. The results showed that water extract has the highest yield ( 13.1%), followed by 70% ethanol (11.1%), the butanol (3.16%). DPPH scavenging capacity of water extracts was the highest (IC50=2.1mg/mL), while 70% ethanol extract （IC50=4.4mg/mL）w

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Huang, Din-Wen, and 黃鼎文. "The Anti-oxidative and Anti-inflammatory Activities of Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) Seed Extract and Its Active Components and Effect on Anti-atherogenic Risk Factors." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/93023670828115569687.

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博士<br>臺灣大學<br>食品科技研究所<br>98<br>The aims of the first part of this study were to investigate the effects of adlay seed extracts on the copper ion-mediated low density lipoprotein (LDL) oxidation and lipopolysaccharide (LPS)-induced inflammatory response in RAW 264.7 macrophages. Adlay hull ethanolic extract (AHE) was sequentially partitioned into ethyl acetate, n-butanol, and water-soluble fractions (AHE-Ea, AHE-Bu and AHE-H2O, respectively). AHE-Ea was further separated into AHE-Ea-A to AHE-Ea-O by column chromatography (CC). AHE-Ea and its subfractions, AHE-Ea-J, AHE-Ea-K, and AHE-Ea-M inhibi

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Lin, Chun-Ya, and 林俊亞. "Studies on the Physicochemical Properties and Anti-limonene Oxidative Effect of the Chitosan-Glucose Complexes Containing Limonene Beverage Emulsion." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/19543673596839226266.

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碩士<br>輔仁大學<br>食品科學系碩士班<br>102<br>Limonene is the main flavor component of lemon oil and is often prepared as an oil-in-water emulsion before being added to beverages. However, limonene-containing oil-in-water emulsions are susceptible to both physical instability and oxidative degradation, leading to loss of aroma and formation of off-flavors. Thus, this study aimed to investigate the inhibitory effect of chitosan-glucose complexes (CG) on limonene oxidation in limonene beverage emulsion (LBE) and the physicochemical properties of CG containing limonene beverage emulsion (CG-LBE). Results of r

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Kang, Chih-Hao, and 康致豪. "Study of common Chinese herb on anti-cancer ability The effect of andrographolide on ultraviolet B radiation induced apoptosis in human keratinocytes HaCaT cell Part II：The study of mediate for effect of oxidative stress by osmanthus fragrans flower extra." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/2ht86z.

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碩士<br>中華醫事科技大學<br>生物科技研究所<br>97<br>We will devide it into two parts to introduction in the study. In part one： Ultraviolet radiation（UV） is the cause of many skin diseases, and being exposing under ultraviolet radiation on long-time bases could cause the injury of keratinocyte cell. The UVB of Ultraviolet radiation could caused the most serious injury to cells, and the UVB could caused of injury in DNA or protein and lading to promoter tumor produced. Therefore, Is been interested by how to suppressed the cell injury. Function of andrographolide could to anti-cancer and anti- immunity. In ou

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"Anti-oxidative, anti-inflammatory and hepato-protective effects of ligustrum robustum." 2000. http://library.cuhk.edu.hk/record=b5890248.

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Lau Kit-Man.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.<br>Includes bibliographical references (leaves 144-164).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Acknowledgement --- p.v<br>Declaration --- p.vi<br>Table of contents --- p.vii<br>List of Tables --- p.x<br>List of Figures --- p.xi<br>List of Abbreviations --- p.xv<br>Chapter Chapter One: --- General Introduction<br>Chapter 1.1 --- Tea and Ku-Ding-Cha --- p.1<br>Chapter 1.2 --- Ligustrum robustum<br>Chapter 1.2.1 --- The plant --- p.4<br>Chapter 1.2.2 --- Chemical constituents --- p.4<br>Chapte

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KUO, TING-CHUN, and 郭庭君. "The Anti-Oxidative And Anti-Inflammatory Effects Of Quercetin In Skin Keratinocyte." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/66582823349328422072.

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碩士<br>長庚科技大學<br>健康產業科技研究所<br>105<br>Quercetin, a naturally occurring polyphenol, shows in vitro as well as in a few animal models to have several potential anti-inflammatory, anti-oxidant and anti-allergic applications. When the excessive inflammation and long-term chronic inflammation, e.g. atopic dermatitis and delayed wound healing, will increase free radical content, deteriorate and oxidize the lesion in the body. Here, we investigated the effects of quercetin on tumor necrosis factor-α (TNF-α)-induced inflammatory mediators in a human skin keratinocyte cell line (HaCaT cells), atopic derm

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Kam, Wing-Yiu, and 甘永耀. "Anti-oxidative and anti-inflammatory effects of naringenin on streptozotocin-induced diabetic mice." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/51132272001533352200.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>98<br>Naringenin (Nar) is a flavonoid compound presented in many plant foods. Previous study has indicated that the compound based on its antioxidant activities could offer hyperglycemic effect in diabetic rodents. In our present study, the protective effect of Nar against renal injury in Streptozotocin-induced diabetic Balb/C mice was examined. Mice were divided into normal group (without DM, normal diet), control group (DM with normal diet), 1% Nar group (DM with 1% Nar), 2% Nar group (DM with 2% Nar). After 4 weeks supplement, results showed that both 1% and 2%

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Ho, Jing-Jing, and 何菁菁. "Anti-oxidative and anti-inflammatory effects of Houttuynia cordata Thunb on diabetic mice." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/6k6ra3.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>102<br>Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by T-cell mediated destruction of pancreatic β-cells, which leads to insulin deficiency. Our previous studies found that intake of Houttuynia cordata Thunb aqueous extract (HCE) improved the high-fat-diet induced lipid disorders in mice; and provided hepatoprotective effects against APAP-induced injury in mice via its antioxidant and anti-inflammatory capacity. Therefore, the aim of this present study was to determine whether HCE could attenuate oxidative and inflammatory stress in STZ-induced dia

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Tsai, Ying-An, and 蔡盈安. "The Anti-oxidative Effects of Fluorescent Gold Nanoclusters in Skin Keratinocyte." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/hb2v5c.

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Dunlop, Kate Elizabeth. "Neuroprotective Effects of a Novel Apple Peel Extract AF4 in a Mouse Model of Hypoxic-Ischemic Brain Injury." 2011. http://hdl.handle.net/10222/15722.

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The neuroprotective effects of AF4, a flavonoid-enriched extract derived from the peel of Northern Spy apples (containing quercetin-3-O-glucoside, quercetin-3-O-galactoside, quercetin-3-O-rhamnoside, quercetin-3-O-rutinoside, epicatechin, and cyanidin-3-O-galactoside) were examined by assessing neuronal loss and motor impairment resulting from hypoxic-ischemic (HI) brain injury in adult C57BL/6 mice. Relative to vehicle treatment (water, 10mL/kg/day), oral administration of AF4 (50 mg/kg/day) for 3 days reduces HI-induced neuronal loss in the striatum and hippocampus, motor impairments, and re

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Hsu, Pei-Chun, and 許培群. "Anti-oxidative and anti-inflammatory effects of Houttuynia cordata on high fat diet-induced obesity mice." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/10798600324359457506.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>100<br>Houttuynia cordata Thunb is a medicinal plant used in traditional Chinese medicine. The major aim of present study was to examine the effects of Houttuynia cordata Thunb aqueous extract (HCE) in mice treated by high fat diet. Butter at 15% (w/w) was used to prepare high fat diet. C57B6 male mice were divided into five groups: (1) normal group (normal diet and water); (2) high dose HCE group (normal diet and 8% of HCE); (3) high fat diet group (15% butter and water); (4) high fat diet with low dose HCE group (15% butter and 4% of HCE) and (5) high fat diet wit

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Chen, Bao-Rong, and 陳堡榮. "Anti-inflammatory and anti-oxidative effects of Antrodia extract and Bilirubin in Raw264.7 and HL-60 cell models." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/53720404813943751765.

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Liu, Chia-Hua, and 劉家華. "Anti-oxidative and Anti-inflammatory Effects of Ethanol Extract from Ulva Lactuca on High Fat Diet Induced Obesity Mice." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/wwxxnd.

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Cheng, Cheng-Wei, and 鄭承瑋. "Anti-oxidative activity and acute liver injury protective effects of Dendrobium species in Taiwan." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/06053275711386434757.

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碩士<br>中國醫藥大學<br>中國藥學研究所碩士班<br>97<br>Anti-oxidative activity and acute liver injury protective effects of Dendrobium species in Taiwan Cheng Wei Cheng Graduate Institute of Chinese Pharmaceutical Sciense, College of Pharmacy, China Medical University Abstract The aims of this study were intended to investigate the anti-oxidative activity, anti-oxidative substance content and hepatoprotective effect of four species of Herba Dendrobii [Dendrobium tosaense (DT), D. linawanum (DL), D. moniliforme(DM), Ephemerantha fimbriata (EL)] in Taiwan. First, we estimated the contents of total flavonoid a

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Wan-YingHuang and 黃琬穎. "Effects of Exercise with Antioxidants on Anti- Senescence and Oxidative Stress in Caenorhabditis elegans." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/eahzj7.

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Ke, Chun-Yen, and 葛俊言. "Study of anti-oxidative and anti-inflammatory effects of Vitamin D3 on the exhaustive exercise and hemorrhagic shock animal models." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/37639673223791416766.

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博士<br>國立交通大學<br>分子醫學與生物工程研究所<br>104<br>Vitamin D3 is a kind of nutrition that well-known necessary for regulate calcium concentration in human blood circulation. Except the well-known function, Vitamin D had been proved that also has anti-inflammation and anti-oxidative stress bioactivity. In this study, we try to understand if Vitamin D3 can actually decrease the inflammation and oxidative stress related damage, and its mechanism. Therefore, we use hemorrhagic shock and exhaustive exercise animal models to mimic inflammation and oxidative stress related damage, and discuss the rescue effect o

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Du, Jing [Verfasser]. "Anti-oxidative stress and Anti-inflammatory effects of atorvastatin improve endothelial dysfunction in experimental diabetes Mellitus / vorgelegt von Jing Du." 2005. http://d-nb.info/975233718/34.

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"In vivo and in vitro studies of the anti-oxidative, anti-inflammatory and anti-apoptotic effects of Gastrodiae Rhizoma water extract on ischemic stroke." 2013. http://library.cuhk.edu.hk/record=b5884430.

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Hung, Sze Man.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 186-192).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstracts also in Chinese.

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Hsieh, Wan-Yu, and 謝琬喻. "Anti-oxidative and anti-aging effects of several extracts of flowers and fruits as well as stilbenoids in Caenorhabditis elegans model." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/84840001044238270777.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>97<br>Aging is a progressive phenomenon of losing physiological function, behavior and cognitive ability over time. Previous studies have pointed out that oxidative stress is an important factor that causes aging. Therefore, some previously shown antioxidative materials were chosen, including water extract of Longan flower (Dimocarpus longan Lour.) (L-W), water extract of mulberry (Morus alba Linn.) (M-W), water extract of roselle (Hibiscus sabdariffa Linn.) (R-W), water fraction from ethanol extract of embryo of Nelumbo nucufera Gaertn.(N-E-W), stilbene glycoside fr

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Ibrahim, Auwal Mohammed. "The in vitro and in vivo anti-oxidative and anti-diabetic effects of some African medicinal plants and the identification of the bioactive compounds." Thesis, 2013. http://hdl.handle.net/10413/11312.

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This thesis examined the in vitro and in vivo anti-oxidative and anti-diabetic activities of five African medicinal plants which are traditionally used for the treatment of diabetes mellitus viz; Ziziphus mucronata, Cassia singueana, Parkia biglobosa, Khaya senegalensis and Vitex doniana. Ethanol, ethyl acetate and aqueous crude extracts of the stem bark, root and leaf samples of each of the plants (a total of 45 crude extracts) were investigated for detailed anti-oxidative activity and the most active crude extract from each plant was selected for further fractionation with solvents of increa

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Tzu-Jiuan, Peng, and 彭紫絹. "The effects of power fitness yoga training on the concentrations of hormones and anti-oxidative status in postmenopausal women." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/07459544695624053607.

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碩士<br>國立新竹教育大學<br>體育學系碩士班<br>94<br>The purpose of this study was to investigate the effects of power fitness yoga training on the concentrations of hormones and anti-oxidative status in postmenopausal women. Thirty healthy postmenopausal women participants were randomly assigned to two groups .Fifteen subjects were in the experimental group (age=55.20 ± 5.77yrs, ht=154 .17±4.44cm, wt=55.13 ±6.12kg), who attended the power fitness yoga training at 74.93 ± 3.31%HRmax for 90 minutes per day, 3 days per week for 12 weeks. Fifteen subjects were in the control group (age=56.53 ± 5.11yrs, ht=155 .17±

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Chang, Ching Mao, and 張清貿. "The efficacy of Chinese herbal formula on Sjögren's syndrome and its mechanism of anti-oxidative and immune modulatory effects." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/v27p52.

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Correia, Catarina Marçal. "(E)-2-styrylchromones: synthesis and evaluation of the inhibitory effects on the oxidative burst produced by human monocytes." Master's thesis, 2021. http://hdl.handle.net/10773/33584.

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Several studies have attributed the onset and progression of several diseases, including degenerative and cardiovascular diseases, cell aging and cancer, to the production of free radicals and inflammatory processes. Consequently, a large number of investigations have been carried out in order to find new, safer and potent antioxidant and anti-inflammatory drugs, and to elucidate their corresponding mechanisms of action. The evaluation of antioxidant vs antiradicalar and anti-inflammatory activity of phenolic compounds, either of natural or synthetic origin, is nowadays an important are

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Lin, Guan-Yu, and 林冠宇. "Investigate the effects of natural anti-oxidative compounds and helicase on the zebrafish and cell models of trinucleotide repeat disease." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/93355e.

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碩士<br>中山醫學大學<br>生物醫學科學學系碩士班<br>106<br>Part 1: Polyglutamine (polyQ) diseases are inherited neurodegenerative disorders caused by an abnormal expansion of a coding trinucleotide (CAG) repeat, which is translated into an elongated glutamine (Q) tract in the respective mutant proteins. It leads to protein misfolding and aggregation, altering the function of neuronal cells and eventually resulting in neurodegeneration. Currently there is no treatment to prevent or cure the disease, only symptomatic treatments exist. We have established transgenic zebrafish and N2a cell lines expressing polyQ prote

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Royer, Christopher Michael. "Exercise & oxidative stress effects on the gastrointestinal barrier & the contribution of dietary pro- & anti-oxidants in Alaskan sled dogs." 2008. http://digital.library.okstate.edu/etd/umi-okstate-2736.pdf.

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Lai, Chia-Jou, and 賴佳柔. "Effects of melatonin or coenzyme Q10 on the nitric oxide system, anti-oxidative enzymes and calcium buffering system of the hypobaric hypoxic rat hippocampus." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/09655308085813689376.

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碩士<br>中國醫藥大學<br>醫學研究所碩士班<br>96<br>Severe hypoxia would alter nitric oxide synthase activity to cause neuronal degeneration or cell death via the overproduction of nitric oxide and impingement on metabolic pathways of related neurochemicals. Fortunately, the anti-oxidative enzymes and calcium buffering system in normal organism attenuate the free radical molecule that produced in cell metabolic process, suggesting it sustains an important role on the oxidative stress and cell protection. Furthermore, recent studies have shown that melatonin and coenzyme Q10 (CoQ10) could attenuate hypoxia or is

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Chipiti, Talent. "In vitro anti-oxidative and carbohydrates digesting enzymes inhibitory effects of some medicinal plants used for the management of diabetes in the Mrewa district, Zimbabwe." Thesis, 2013. http://hdl.handle.net/10413/11189.

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