Academic literature on the topic 'Anti-retinal autoantibodies'

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Journal articles on the topic "Anti-retinal autoantibodies"

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Adamus, Grazyna. "Current techniques to accurately measure anti-retinal autoantibodies." Expert Review of Ophthalmology 15, no. 2 (March 3, 2020): 111–18. http://dx.doi.org/10.1080/17469899.2020.1739522.

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Hooks, J. J., C. Percopo, Y. Wang, and B. Detrick. "Retina and retinal pigment epithelial cell autoantibodies are produced during murine coronavirus retinopathy." Journal of Immunology 151, no. 6 (September 15, 1993): 3381–89. http://dx.doi.org/10.4049/jimmunol.151.6.3381.

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Abstract The murine coronavirus, mouse hepatitis virus (MHV), JHM strain, induces a biphasic retinal disease in adult BALB/c mice. In the early phase of the disease, day 1 to 7, a retinal vasculitis is noted and is associated with the presence of virus particles. In the late phase of the disease, day 10 to 140, a retinal degeneration is observed and is associated with the absence of both virus particles and inflammatory cells. We show that the retinal degenerative process is also associated with the presence of antiretinal autoantibodies. In total, 22 of 23 sera collected from 10 to 70 days af
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Garweg, Justus G., Yvonne de Kozak, Brigitte Goldenberg, and Matthias Boehnke. "Anti-retinal autoantibodies in experimental ocular and systemic toxoplasmosis." Graefe's Archive for Clinical and Experimental Ophthalmology 248, no. 4 (December 3, 2009): 573–84. http://dx.doi.org/10.1007/s00417-009-1242-z.

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Cheung, C. M. G., and S. P. Chee. "Anti-retinal autoantibodies-positive autoimmune retinopathy in cytomegalovirus-positive anterior uveitis." British Journal of Ophthalmology 94, no. 3 (March 1, 2010): 380–81. http://dx.doi.org/10.1136/bjo.2009.170464.

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Adamus, Grazyna, Rachel Champaigne, and Sufang Yang. "Occurrence of major anti-retinal autoantibodies associated with paraneoplastic autoimmune retinopathy." Clinical Immunology 210 (January 2020): 108317. http://dx.doi.org/10.1016/j.clim.2019.108317.

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Shinohara, Yoichiro, Ryo Mukai, Shinji Ueno, and Hideo Akiyama. "Clinical Findings of Melanoma-Associated Retinopathy with anti-TRPM1 Antibody." Case Reports in Ophthalmological Medicine 2021 (September 8, 2021): 1–5. http://dx.doi.org/10.1155/2021/6607441.

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Introduction. We report the clinical features and clinical course of melanoma-associated retinopathy (MAR), in which autoantibodies against the transient receptor potential cation channel subfamily M member 1 (TRPM1) were detected. Case Presentation. A 74-year-old man was referred to our hospital for treatment of bilateral vision loss. The best-corrected visual acuity was 20/100 in the right eye and 20/200 in the left eye. His electroretinogram (ERG) showed a reduced b-wave and a normal dark-adapted a-wave in both eyes. Optical coherence tomography (OCT) revealed loss of the interdigitation zo
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Hurez, Vincent, Michel D. Kazatchkine, Tchavdar Vassilev, Sheela Ramanathan, Anastas Pashov, Bertrand Basuyaux, Yvonne de Kozak, Blanche Bellon, and Srini V. Kaveri. "Pooled Normal Human Polyspecific IgM Contains Neutralizing Anti-Idiotypes to IgG Autoantibodies of Autoimmune Patients and Protects From Experimental Autoimmune Disease." Blood 90, no. 10 (November 15, 1997): 4004–13. http://dx.doi.org/10.1182/blood.v90.10.4004.

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Abstract Normal human serum contains IgM antibodies that regulate the natural autoantibody activity of IgG in autologous serum. In the present study, we show that pooled normal human IgM (IVIgM) purified from plasma of more than 2,500 healthy donors and processed in a similar fashion to that of therapeutic preparations of pooled normal human IgG (IVIg) suppresses activity of IgG autoantibodies purified from the serum of patients with autoimmune diseases in vitro. The inhibitory effect of IVIgM was greater or equivalent to that of IVIg on a molar basis. We show that IVIgM contains anti-idiotypi
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Adamus, G., D. Amundson, G. M. Seigel та M. Machnicki. "Anti-Enolase-α Autoantibodies in Cancer-Associated Retinopathy: Epitope Mapping and Cytotoxicity on Retinal Cells". Journal of Autoimmunity 11, № 6 (грудень 1998): 671–77. http://dx.doi.org/10.1006/jaut.1998.0239.

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Khaddour, Karam, Sangeeta Khanna, Michael Ansstas, Ishaan Jakhar, Sonika Dahiya, Laurin Council, and George Ansstas. "Normalization of electroretinogram and symptom resolution of melanoma-associated retinopathy with negative autoantibodies after treatment with programmed death-1 (PD-1) inhibitors for metastatic melanoma." Cancer Immunology, Immunotherapy 70, no. 9 (February 5, 2021): 2497–502. http://dx.doi.org/10.1007/s00262-021-02875-x.

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AbstractMelanoma-associated retinopathy (MAR) is a paraneoplastic syndrome that involves the production of autoantibodies which can cross-react with retinal epitopes leading to visual symptoms. Autoantibodies can target intracellular proteins, and only a few are directed against membrane proteins. This discrepancy in autoantibody–protein target can translate into different immune responses (T-cell mediated vs B-cell mediated). Historically, treatment of MAR has focused on surgical reduction or immunosuppressive medication, mainly glucocorticoids. However, tumor resection is not relevant in met
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Gyoten, Daichi, Shinji Ueno, Satoshi Okado, Taro Chaya, Shunsuke Yasuda, Takeshi Morimoto, Mineo Kondo, et al. "Broad locations of antigenic regions for anti-TRPM1 autoantibodies in paraneoplastic retinopathy with retinal ON bipolar cell dysfunction." Experimental Eye Research 212 (November 2021): 108770. http://dx.doi.org/10.1016/j.exer.2021.108770.

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Dissertations / Theses on the topic "Anti-retinal autoantibodies"

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Cherepanoff, Svetlana. "Age-related macular degeneration: histopathological and serum autoantibody studies." Thesis, The University of Sydney, 2007. http://hdl.handle.net/2123/2464.

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BACKGROUND: The accumulation of abnormal extracellular deposits beneath the retinal pigment epithelium characterises the pathology of early age-related macular degeneration. However, the histopathological threshold at which age-related changes become early AMD is not defined, and the effect of each of the deposits (basal laminar deposit and membranous debris) on disease progression is poorly understood. Evidence suggests that macrophages play a key role in the development of AMD lesions, but the influence of basal laminar deposit (BLamD) and membranous debris on the recruitment and programming
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Cherepanoff, Svetlana. "Age-related macular degeneration: histopathological and serum autoantibody studies." University of Sydney, 2008. http://hdl.handle.net/2123/2464.

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Doctor of Philosophy (PhD)<br>BACKGROUND: The accumulation of abnormal extracellular deposits beneath the retinal pigment epithelium characterises the pathology of early age-related macular degeneration. However, the histopathological threshold at which age-related changes become early AMD is not defined, and the effect of each of the deposits (basal laminar deposit and membranous debris) on disease progression is poorly understood. Evidence suggests that macrophages play a key role in the development of AMD lesions, but the influence of basal laminar deposit (BLamD) and membranous debris on t
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Conference papers on the topic "Anti-retinal autoantibodies"

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Silva, Vitória Pimentel da, Lucas Immich Gonçalves, Giordani Rodrigues dos Passos, Maísa Kappel, Mayumi Charão, and Jefferson Becker. "Vogt-Koyanagi-Harada Syndrome: case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.637.

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Context: Red eye complaints are common in medical practice. Trauma, infection and autoimmune disorders are possible causes. It is essential to diagnose early to avoid sequelae. Case report: Female, 58 years old, 30 days of progression of bilateral frontal and retro-orbital headache associated with red eye and decreased visual acuity in both eyes, otalgia and tinnitus in the left ear. No trauma history. She started treatment in another hospital with acyclovir for suspected viral meningitis and was referred for evaluation after 10 days due to the lack of improvement. In our evaluation, the patie
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