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Journal articles on the topic 'Anti-retinal autoantibodies'

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1

Adamus, Grazyna. "Current techniques to accurately measure anti-retinal autoantibodies." Expert Review of Ophthalmology 15, no. 2 (March 3, 2020): 111–18. http://dx.doi.org/10.1080/17469899.2020.1739522.

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2

Hooks, J. J., C. Percopo, Y. Wang, and B. Detrick. "Retina and retinal pigment epithelial cell autoantibodies are produced during murine coronavirus retinopathy." Journal of Immunology 151, no. 6 (September 15, 1993): 3381–89. http://dx.doi.org/10.4049/jimmunol.151.6.3381.

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Abstract The murine coronavirus, mouse hepatitis virus (MHV), JHM strain, induces a biphasic retinal disease in adult BALB/c mice. In the early phase of the disease, day 1 to 7, a retinal vasculitis is noted and is associated with the presence of virus particles. In the late phase of the disease, day 10 to 140, a retinal degeneration is observed and is associated with the absence of both virus particles and inflammatory cells. We show that the retinal degenerative process is also associated with the presence of antiretinal autoantibodies. In total, 22 of 23 sera collected from 10 to 70 days af
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3

Garweg, Justus G., Yvonne de Kozak, Brigitte Goldenberg, and Matthias Boehnke. "Anti-retinal autoantibodies in experimental ocular and systemic toxoplasmosis." Graefe's Archive for Clinical and Experimental Ophthalmology 248, no. 4 (December 3, 2009): 573–84. http://dx.doi.org/10.1007/s00417-009-1242-z.

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4

Cheung, C. M. G., and S. P. Chee. "Anti-retinal autoantibodies-positive autoimmune retinopathy in cytomegalovirus-positive anterior uveitis." British Journal of Ophthalmology 94, no. 3 (March 1, 2010): 380–81. http://dx.doi.org/10.1136/bjo.2009.170464.

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5

Adamus, Grazyna, Rachel Champaigne, and Sufang Yang. "Occurrence of major anti-retinal autoantibodies associated with paraneoplastic autoimmune retinopathy." Clinical Immunology 210 (January 2020): 108317. http://dx.doi.org/10.1016/j.clim.2019.108317.

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6

Shinohara, Yoichiro, Ryo Mukai, Shinji Ueno, and Hideo Akiyama. "Clinical Findings of Melanoma-Associated Retinopathy with anti-TRPM1 Antibody." Case Reports in Ophthalmological Medicine 2021 (September 8, 2021): 1–5. http://dx.doi.org/10.1155/2021/6607441.

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Introduction. We report the clinical features and clinical course of melanoma-associated retinopathy (MAR), in which autoantibodies against the transient receptor potential cation channel subfamily M member 1 (TRPM1) were detected. Case Presentation. A 74-year-old man was referred to our hospital for treatment of bilateral vision loss. The best-corrected visual acuity was 20/100 in the right eye and 20/200 in the left eye. His electroretinogram (ERG) showed a reduced b-wave and a normal dark-adapted a-wave in both eyes. Optical coherence tomography (OCT) revealed loss of the interdigitation zo
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7

Hurez, Vincent, Michel D. Kazatchkine, Tchavdar Vassilev, Sheela Ramanathan, Anastas Pashov, Bertrand Basuyaux, Yvonne de Kozak, Blanche Bellon, and Srini V. Kaveri. "Pooled Normal Human Polyspecific IgM Contains Neutralizing Anti-Idiotypes to IgG Autoantibodies of Autoimmune Patients and Protects From Experimental Autoimmune Disease." Blood 90, no. 10 (November 15, 1997): 4004–13. http://dx.doi.org/10.1182/blood.v90.10.4004.

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Abstract Normal human serum contains IgM antibodies that regulate the natural autoantibody activity of IgG in autologous serum. In the present study, we show that pooled normal human IgM (IVIgM) purified from plasma of more than 2,500 healthy donors and processed in a similar fashion to that of therapeutic preparations of pooled normal human IgG (IVIg) suppresses activity of IgG autoantibodies purified from the serum of patients with autoimmune diseases in vitro. The inhibitory effect of IVIgM was greater or equivalent to that of IVIg on a molar basis. We show that IVIgM contains anti-idiotypi
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8

Adamus, G., D. Amundson, G. M. Seigel та M. Machnicki. "Anti-Enolase-α Autoantibodies in Cancer-Associated Retinopathy: Epitope Mapping and Cytotoxicity on Retinal Cells". Journal of Autoimmunity 11, № 6 (грудень 1998): 671–77. http://dx.doi.org/10.1006/jaut.1998.0239.

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9

Khaddour, Karam, Sangeeta Khanna, Michael Ansstas, Ishaan Jakhar, Sonika Dahiya, Laurin Council, and George Ansstas. "Normalization of electroretinogram and symptom resolution of melanoma-associated retinopathy with negative autoantibodies after treatment with programmed death-1 (PD-1) inhibitors for metastatic melanoma." Cancer Immunology, Immunotherapy 70, no. 9 (February 5, 2021): 2497–502. http://dx.doi.org/10.1007/s00262-021-02875-x.

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AbstractMelanoma-associated retinopathy (MAR) is a paraneoplastic syndrome that involves the production of autoantibodies which can cross-react with retinal epitopes leading to visual symptoms. Autoantibodies can target intracellular proteins, and only a few are directed against membrane proteins. This discrepancy in autoantibody–protein target can translate into different immune responses (T-cell mediated vs B-cell mediated). Historically, treatment of MAR has focused on surgical reduction or immunosuppressive medication, mainly glucocorticoids. However, tumor resection is not relevant in met
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10

Gyoten, Daichi, Shinji Ueno, Satoshi Okado, Taro Chaya, Shunsuke Yasuda, Takeshi Morimoto, Mineo Kondo, et al. "Broad locations of antigenic regions for anti-TRPM1 autoantibodies in paraneoplastic retinopathy with retinal ON bipolar cell dysfunction." Experimental Eye Research 212 (November 2021): 108770. http://dx.doi.org/10.1016/j.exer.2021.108770.

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11

Piantoni, S., F. Regola, S. Masneri, C. Nalli, C. Bazzani, C. Rossini, G. Chiarini, et al. "POS0593 THE REDUCTION OF RETINAL MICROVASCULAR ALTERATIONS AND THE DECREASE OF A POTENTIALLY RELATED T-CELL SUBSET IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS TREATED WITH ABATACEPT." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 530.1–530. http://dx.doi.org/10.1136/annrheumdis-2021-eular.483.

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Background:T-cells play a pivotal role in the pathogenesis of rheumatoid arthritis (RA) and in its cardiovascular (CV) comorbidities, acting at microvascular level [1]. Since small artery remodeling is the earliest form of target organ damage in hypertension, the evaluation of microvascular alterations might provide clinically useful information. The evaluation of retinal arterioles is a non-invasive technique to identify a precocious microvascular damage, which is related to an increase of the wall-to-lumen ratio (WLR) [2]. CD3+CD31+CXCR4+ T-cells may be involved in damaged endothelium repair
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12

Sim, Shaun Sebastian, Chee Wai Wong, Quan V. Hoang, Shu Yen Lee, Tien Yin Wong, and Chui Ming Gemmy Cheung. "Anti-retinal autoantibodies in myopic macular degeneration: a pilot study." Eye, October 28, 2020. http://dx.doi.org/10.1038/s41433-020-01241-y.

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13

Adamus, Grazyna. "Are Anti-Retinal Autoantibodies a Cause or a Consequence of Retinal Degeneration in Autoimmune Retinopathies?" Frontiers in Immunology 9 (April 16, 2018). http://dx.doi.org/10.3389/fimmu.2018.00765.

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14

Adamus, Grazyna. "Significance of Anti-retinal Autoantibodies in Cancer-associated Retinopathy with Gynecological Cancers." Journal of Clinical & Experimental Ophthalmology 04, no. 06 (2013). http://dx.doi.org/10.4172/2155-9570.1000307.

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15

Adamus, Grazyna, Emily Y. Chew, Frederick L. Ferris, and Michael L. Klein. "Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration." BMC Ophthalmology 14, no. 1 (December 2014). http://dx.doi.org/10.1186/1471-2415-14-154.

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16

Pawestri, Aulia Rahmi, Niracha Arjkongharn, Ragkit Suvannaboon, Aekkachai Tuekprakhon, Vichien Srimuninnimit, Suthipol Udompunthurak, La-ongsri Atchaneeyasakul, Ajchara Koolvisoot, and Adisak Trinavarat. "Autoantibody profiles and clinical association in Thai patients with autoimmune retinopathy." Scientific Reports 11, no. 1 (July 22, 2021). http://dx.doi.org/10.1038/s41598-021-94377-0.

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AbstractAutoimmune retinopathy (AIR) is a rare immune-mediated inflammation of the retina. The autoantibodies against retinal proteins and glycolytic enzymes were reported to be involved in the pathogenesis. This retrospective cohort study assessed the antiretinal autoantibody profiles and their association with clinical outcomes of AIR patients in Thailand. We included 44 patients, 75% were females, with the overall median age of onset of 48 (17–74, IQR 40–55.5) years. Common clinical presentations were nyctalopia (65.9%), blurred vision (52.3%), constricted visual field (43.2%), and nonrecor
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17

van Romunde, Saskia H. M., Daphne P. C. Vergouwen, Daniela Iacovello, Dave L. Roelen, Robert M. Verdijk, Josianne C. E. M. ten Berge, Grazia Pertile, Marco W. J. Schreurs, and Jan C. van Meurs. "Destructive inflammatory reaction after an autologous retinal pigment epithelium and choroid transplantation: no detection of an auto-immune response." Journal of Ophthalmic Inflammation and Infection 12, no. 1 (August 26, 2022). http://dx.doi.org/10.1186/s12348-022-00305-2.

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Abstract Purpose Five patients who underwent uncomplicated retinal pigment epithelium (RPE)-choroid transplantation for neovascular age-related macular degeneration developed a destructive inflammatory reaction causing subretinal fluid accumulation and extensive RPE atrophy in the graft. We hypothesized that this inflammation could be caused by an auto-immune response against the graft, resulting in circulating auto-antibodies. The aim of our study was to examine a potential autoimmune origin, which would allow a more targeted therapy approach. Methods Five above-mentioned patients and four co
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