Log in

Relevant bibliographies by topics / Anti-seizure / Journal articles

To see the other types of publications on this topic, follow the link: Anti-seizure.

Journal articles on the topic 'Anti-seizure'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Anti-seizure.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

de Bruijn, Marienke A. A. M., Agnes van Sonderen, Marleen H. van Coevorden-Hameete, et al. "Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABABR encephalitis." Neurology 92, no. 19 (2019): e2185-e2196. http://dx.doi.org/10.1212/wnl.0000000000007475.

Full text

Abstract:

ObjectiveThis nationwide cohort study evaluates seizure responses to immunotherapy and antiepileptic drugs (AEDs) in patients with anti-leucine-rich glioma-inactivated 1 (LGI1), anti-NMDA receptor (NMDAR), and anti-gamma-aminobutyric-acid B receptor (GABABR) encephalitis.MethodsAnti-LGI1, anti-NMDAR, and anti-GABABR encephalitis patients with new-onset seizures were included. Medical information about disease course, AEDs and immunotherapies used, effects, and side effects were collected. Outcome measures were (1) seizure freedom while using AEDs or immunotherapy, (2) days to seizure freedom f

APA, Harvard, Vancouver, ISO, and other styles

2

Dusabimana, Alfred, Solomon Tsebeni Wafula, Stephen Jada Raimon, et al. "Effect of Ivermectin Treatment on the Frequency of Seizures in Persons with Epilepsy Infected with Onchocerca volvulus." Pathogens 10, no. 1 (2020): 21. http://dx.doi.org/10.3390/pathogens10010021.

Full text

Abstract:

A clinical trial performed in the Democratic Republic of Congo (DRC), among persons with epilepsy (PWE) infected with Onchocerca volvulus treated with anti-seizure medication suggested that ivermectin reduces the seizure frequency. We assessed the effect of ivermectin treatment on seizure frequency in PWE with and without anti-seizure medication in three onchocerciasis endemic areas (Maridi, South Sudan; Aketi, DRC; and Mahenge, Tanzania). Pre- and 3–5 months post-ivermectin microfilariae densities in skin snips and seizure frequency were assessed. After ivermectin, the median (IQR) percentage

APA, Harvard, Vancouver, ISO, and other styles

3

Brattiya, Keerthana, and Bhuvaneshwari K. "SEIZURES WITH ANTI-SEIZURE DRUG." Asian Journal of Pharmaceutical and Clinical Research 10, no. 12 (2017): 3. http://dx.doi.org/10.22159/ajpcr.2017.v10i12.21285.

Full text

Abstract:

This case study is to report and explore the etiology of a case of refractory seizures due to overdosage of phenytoin tablets. A case report from the Department of Neurology generated through voluntary adverse drug reaction (ADR)reporting stated phenytoin overdosage leading to refractory status epilepticus which did not respond to any of the antiepileptic drugs. A 33-year-old female patient with the history of consumption 15 tablets of phenytoin and a metal ring as part of a suicidal bid a month ago, presented with unconsciousness, persistent seizures, and gangrene of fingers. Magnetic resonan

APA, Harvard, Vancouver, ISO, and other styles

4

Allen, Mary A. "Don't Switch Anti-Seizure Medications." American Journal of Nursing 88, no. 2 (1988): 166. http://dx.doi.org/10.2307/3425724.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

&NA;. "DONʼT SWITCH ANTI-SEIZURE MEDICATIONS". AJN, American Journal of Nursing 88, № 2 (1988): 166–69. http://dx.doi.org/10.1097/00000446-198802000-00014.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Keezer, Mark. "Game changing anti-seizure medicines." Journal of the Neurological Sciences 455 (December 2023): 120899. http://dx.doi.org/10.1016/j.jns.2023.120899.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Munshi, Renuka, Chaitali Pilliwar, and Miteshkumar Maurya. "An audit of prescribing pattern of anti-epileptic drugs with its effect on therapeutic drug levels and seizure control at a tertiary care public hospital." Ghana Medical Journal 57, no. 3 (2023): 191–97. http://dx.doi.org/10.4314/gmj.v57i3.5.

Full text

Abstract:

Objective: The study objective was to evaluate the prescription pattern and use of anti-seizure medications (ASMs) in patients with a seizure disorder and to evaluate if a change in the ASM dose had a beneficial effect on seizure control, observed through Therapeutic Drug Monitoring [TDM] level of ASMs.Methods: Details of anti-seizure medications with their therapeutic levels in the blood of patients with seizure disorder were analysed.Design: Hospital-based retrospective analysis of patient case recordsSettings: Therapeutic Drug Monitoring OPD of a tertiary care public teaching hospitalPartic

APA, Harvard, Vancouver, ISO, and other styles

8

Gangopadhyay, Tanmoy, Ananya Mandal, and Uma Shanker Keshri. "Fluoxetine enhances maximal electroshock seizure threshold in Albino rat model when compared to phenytoin." International Journal of Basic & Clinical Pharmacology 7, no. 1 (2017): 138. http://dx.doi.org/10.18203/2319-2003.ijbcp20175689.

Full text

Abstract:

Background: Individuals with epilepsy have a higher incidence of psychiatric disorders than person without epilepsy. Epidemiological studies have shown that the co-morbidity of epilepsy and depression to be high as 50%. The conventional anti-depressants are believed to lower the seizure threshold making it difficult to treat the co-morbid depression, but animal studies have shown SSRIs, a common anti-depressant, to have anti-convulsant properties. So, we propose to study the anticonvulsant effects of fluoxetine, a SSRI, in albino rats against maximal electroshock seizure and to compare against

APA, Harvard, Vancouver, ISO, and other styles

9

Avachat, Charul, Jessica M. Barry, Xintian Lyu, Catherine M. Sherwin, and Angela K. Birnbaum. "Management of Anti-Seizure Medications during Pregnancy: Advancements in The Past Decade." Pharmaceutics 14, no. 12 (2022): 2733. http://dx.doi.org/10.3390/pharmaceutics14122733.

Full text

Abstract:

Management of seizures often involves continuous medication use throughout a patient’s life, including when a patient is pregnant. The physiological changes during pregnancy can lead to altered drug exposure to anti-seizure medications, increasing patient response variability. In addition, subtherapeutic anti-seizure medication concentrations in the mother may increase seizure frequency, raising the risk of miscarriage and preterm labor. On the other hand, drug exposure increases can lead to differences in neurodevelopmental outcomes in the developing fetus. Established pregnancy registries pr

APA, Harvard, Vancouver, ISO, and other styles

10

Jaramillo, Maria A., Timothy Pham, Sohail Kamrudin, Rahul Khanna, and Atul Maheshwari. "Seizure exacerbation with anti-seizure medications in adult patients with epilepsy." Epilepsy Research 181 (March 2022): 106885. http://dx.doi.org/10.1016/j.eplepsyres.2022.106885.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Jha, Rohan, Melissa M. J. Chua, David D. Liu, R. Mark Richardson, Steven Tobochnik, and John D. Rolston. "Beyond seizure freedom: Reduction in anti-seizure medication after epilepsy surgery." Epilepsy Research 208 (December 2024): 107473. http://dx.doi.org/10.1016/j.eplepsyres.2024.107473.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Dubenko, A. Ye, L. B. Maryenko, T. A. Litovchenko, A. V. Litovchenko, K. M. Maryenko, and H. I. Seliukov. "Acute symptomatic seizure: structural brain lesions, metabolic disorders, anti-seizure medications." EMERGENCY MEDICINE 21, no. 1 (2025): 31–42. https://doi.org/10.22141/2224-0586.21.1.2025.1830.

Full text

Abstract:

Seizures that occur in close temporal relation to brain lesions and do not recur after resolution of the pathological condition or elimination of the factor that caused it should be considered as acute symptomatic seizures. They differ from unprovoked seizures and epilepsy because the risk of recurrence is significantly lower and there is no long-term predisposition to further seizures. The most important causes of acute symptomatic seizures in adults are both diseases that lead to structural brain damage, such as ischemic stroke, cerebral hemorrhage, brain trauma, or encephalitis, and factors

APA, Harvard, Vancouver, ISO, and other styles

13

Simeone, Timothy A., Kristina A. Simeone, and Jong M. Rho. "Ketone Bodies as Anti-Seizure Agents." Neurochemical Research 42, no. 7 (2017): 2011–18. http://dx.doi.org/10.1007/s11064-017-2253-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

French, Jacqueline. "Matching anti-seizure medicines to patients." Journal of the Neurological Sciences 455 (December 2023): 120898. http://dx.doi.org/10.1016/j.jns.2023.120898.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

de Miranda, Fernanda Barros, Lucia Emanueli Schimith, Dennis Guilherme da Costa Silva, et al. "Effects of Polydatin on Pentylenetetrazol-Induced Seizures in Zebrafish Larvae." Future Pharmacology 5, no. 2 (2025): 22. https://doi.org/10.3390/futurepharmacol5020022.

Full text

Abstract:

Background/Objectives: Epilepsy is a common neurological condition characterized by the occurrence of a seizure. It affects around 50 million individuals worldwide, and despite the large quantity of anti-seizure medications available, 30% of epileptic patients still suffer from seizures. Therefore, it is necessary to find new therapeutic options. Interestingly, polydatin has shown promising effects on epilepsy treatment due to its antioxidant and anti-inflammatory properties. Thus, this study aimed to evaluate the effects of polydatin (200, 300, and 400 µM) on a pentylenetetrazol (PTZ)-induced

APA, Harvard, Vancouver, ISO, and other styles

16

Brothwell, Morag, Jennifer Collins, and Louise Dulley. "ANTI-SEIZURE MEDICATION IN GLIOMA PATIENTS: GETTING IT RIGHT fiRST TIME." Neuro-Oncology 25, Supplement_3 (2023): iii20. http://dx.doi.org/10.1093/neuonc/noad147.084.

Full text

Abstract:

Abstract AIMS Seizures affect between 60–90% patients with low grade glioma and between 40–60% patients with high grade glioma. There are no national guidelines for seizure management in glioma patients. This quality improvement project investigated the initiation of anti-seizure medication in glioma patients with new-onset seizures. METHOD A retrospective review was undertaken of new glioma patients’ electronic notes (2020-2022) seen in Oncology clinic at Colchester hospital. RESULTS Thirty-seven patients (twenty-five glioblastoma IDH-wt, two grade 3 astrocytoma IDH-mutant, one grade 2 astroc

APA, Harvard, Vancouver, ISO, and other styles

17

Zena, Dawit, Abilo Tadesse, Nebiyu Bekele, Samson Yaregal, Nuria Sualih, and Edilawit Worku. "Seizure control and its associated factors among epileptic patients at Neurology Clinic, University of Gondar hospital, Northwest Ethiopia." SAGE Open Medicine 10 (January 2022): 205031212211006. http://dx.doi.org/10.1177/20503121221100612.

Full text

Abstract:

Background: Epilepsy is characterized by two or more unprovoked recurrent seizures, which often respond to available antiseizure medications. However, seizure control among epileptic patients in the developing world is low. Factors determining seizure control among epileptic patients were not evidently explored in the study setting. Objectives: This study aimed to determine the magnitude of uncontrolled seizures and associated factors among epileptic patients at the University of Gondar hospital. Methods: This cross-sectional study was conducted at the University of Gondar hospital, Northwest

APA, Harvard, Vancouver, ISO, and other styles

18

Das, Dhananjoy, Wahida Akther, Tanuka Barua, Rehena Ahmed, Nazrul Quader Shikder, and Mahmood A. Chowdhury. "Adherence to Anti-Seizure Medications in Children with Epilepsy Attending a Tertiary Care Center in Bangladesh." Chattagram Maa-O-Shishu Hospital Medical College Journal 22, no. 1 (2023): 38–43. http://dx.doi.org/10.3329/cmoshmcj.v22i1.67833.

Full text

Abstract:

Background: Epilepsy is one of the most common neurological morbidities in children worldwide. Anti-Seizure Medication (ASM) is the mainstay of epilepsy treatment. Adherence to Anti-Seizure Medication (ASM) is the key to achieving seizure remission. So this study aimed to assess the adherence to anti-seizure medication among children with epilepsy and to identify the factors that influence adherence. Materials and methods: It was a cross-sectional study involving Infants and children aged six months to twelve years old with seizure disorder irrespective of etiology, taking anti-seizure m

APA, Harvard, Vancouver, ISO, and other styles

19

Nabila Zafira, Safa, Diva Aulya Kemuning, Nur Izzatush Sholihah, and Muhammad Nooradi Praramdana. "Penggunaan Antikejang Pada Cedera Kepala: Tinjauan Sistematis." Jurnal Syntax Fusion 2, no. 01 (2022): 134–51. http://dx.doi.org/10.54543/fusion.v2i01.138.

Full text

Abstract:

Brain injury can occur due to direct head impact and injury due to brain tissue damage such as hypotension, hypoxia, acidosis and edema. Brain injury will trigger an inflammatory process that can lead to post-trauma seizures. The use of anti- epileptic drugs is intended as a seizure prophylaxis so that it can reduce the incidence of seizures in the early phase of injury. Quantify the effectivity of anti seizure usage on post traumatic seizure accident. The method used in this paper is a relevant systematic review from various references and focuses on the use of analgesics for the management o

APA, Harvard, Vancouver, ISO, and other styles

20

Palic, Ilija. "The Use of Anti-Seizure Medications in Neonatal Intensive Care Unit." SVOA Paediatrics 4, no. 2 (2025): 48–54. https://doi.org/10.58624/svoapd.2025.04.008.

Full text

Abstract:

Neonatal seizures are the most common emergency neurological condition. Neonatal seizures require emergency treatment to prevent further brain injury. The most effective is causal treatment, such as treatment of transient metabolic disturbances, systemic and intracranial infections. However, anti-seizure medications are important for the treatment of seizures in high-risk neonates in whom seizures are not expected to resolve spontaneously. The International League Against Epilepsy developed evidence-based recommendations about anti-seizure medication and treatment of neonatal seizures. Phenoba

APA, Harvard, Vancouver, ISO, and other styles

21

Lin, Tzu-Yu, Chih-Yu Hung, Kuan-Ming Chiu, Ming-Yi Lee, Cheng-Wei Lu, and Su-Jane Wang. "Neferine, an Alkaloid from Lotus Seed Embryos, Exerts Antiseizure and Neuroprotective Effects in a Kainic Acid-Induced Seizure Model in Rats." International Journal of Molecular Sciences 23, no. 8 (2022): 4130. http://dx.doi.org/10.3390/ijms23084130.

Full text

Abstract:

Current anti-seizure drugs fail to control approximately 30% of epilepsies. Therefore, there is a need to develop more effective anti-seizure drugs, and medicinal plants provide an attractive source for new compounds. This study aimed to evaluate the possible anti-seizure and neuroprotective effects of neferine, an alkaloid from the lotus seed embryos of Nelumbo nucifera, in a kainic acid (KA)-induced seizure rat model and its underlying mechanisms. Rats were intraperitoneally (i.p.) administrated neferine (10 and 50 mg/kg) 30 min before KA injection (15 mg/kg, i.p.). Neferine pretreatment inc

APA, Harvard, Vancouver, ISO, and other styles

22

Holmes, Mark. "Rufinamide: A broad-spectrum anti-seizure medication." Journal of Pediatric Epilepsy 01, no. 02 (2015): 075–76. http://dx.doi.org/10.3233/pep-2012-013.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Beimer, Nicholas J., and Linda M. Selwa. "Seizure semiology of anti-LGI1 antibody encephalitis." Epileptic Disorders 19, no. 4 (2017): 461–64. http://dx.doi.org/10.1684/epd.2017.0936.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Hartman, Adam L., Polan Santos, Kenneth J. O'Riordan, Carl E. Stafstrom, and J. Marie Hardwick. "Potent anti-seizure effects of D-leucine." Neurobiology of Disease 82 (October 2015): 46–53. http://dx.doi.org/10.1016/j.nbd.2015.05.013.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Karceski, Steven. "Pregnancy, anti-seizure medications, and seizuresAbout epilepsy." Neurology 91, no. 13 (2018): e1271-e1274. http://dx.doi.org/10.1212/wnl.0000000000006231.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Tatum, William O. "Recent and Emerging Anti-seizure Drugs: 2013." Current Treatment Options in Neurology 15, no. 4 (2013): 505–18. http://dx.doi.org/10.1007/s11940-013-0245-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Rho, Jong M., and H. Steve White. "Brief history of anti‐seizure drug development." Epilepsia Open 3, S2 (2018): 114–19. http://dx.doi.org/10.1002/epi4.12268.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Zaccara, Gaetano, and Dieter Schmidt. "Do traditional anti-seizure drugs have a future? A review of potential anti-seizure drugs in clinical development." Pharmacological Research 104 (February 2016): 38–48. http://dx.doi.org/10.1016/j.phrs.2015.12.011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Abraham, Annette, Javier A. Bustos, Hélène Carabin, et al. "The effectiveness of anti-inflammatory and anti-seizure medication for individuals with single enhancing lesion neurocysticercosis: A meta-analysis and expert group-based consensus recommendations." PLOS Neglected Tropical Diseases 15, no. 3 (2021): e0009193. http://dx.doi.org/10.1371/journal.pntd.0009193.

Full text

Abstract:

Single brain enhancing lesions (SEL) are the most common presentation of neurocysticercosis (NCC) observed on neuroimaging in people presenting with epileptic seizures not only on the Indian sub-continent and in travelers returning from cysticercosis-endemic regions, but are also present in other parts of the world. The aim of this study, which consisted of a systematic review (CRD42019087665), a meta-analysis and an expert group consultation, was to reach consensus on the best anti-seizure medication and anti-inflammatory treatment for individuals with SEL NCC. Standard literature review meth

APA, Harvard, Vancouver, ISO, and other styles

30

Abizadeh, Marzieh, Soomaayeh Heysieattalab, Negin Saeedi, et al. "Ameliorating Effects of Dorema ammoniacum on PTZ-Induced Seizures and Epileptiform Brain Activity in Rats." Planta Medica 86, no. 18 (2020): 1353–62. http://dx.doi.org/10.1055/a-1229-4436.

Full text

Abstract:

AbstractThe objective of the current study was to investigate the anti-epileptogenic and anticonvulsant effects of Dorema ammoniacum gum, which is used in Iranian traditional medicine for the treatment of seizures. Animals received pentylenetetrazol (IP, 30 mg/kg/48 h) for inducing seizures. Five different seizure stages were evaluated for 20 min and parameters including maximum seizure stage, the latency to the onset of stage 4, stage 4 duration, and seizure duration were measured. D. ammoniacum (50 and 100 mg/kg) or its vehicle was administered 30 min before or after pentylenetetrazol inject

APA, Harvard, Vancouver, ISO, and other styles

31

Rangarajan, Punitha, Kulandaiammal Moorthy, and Arunan Subbiah. "Observational study on the utilization pattern of adjuvant anti-epileptics and their adverse effects." International Journal of Basic & Clinical Pharmacology 9, no. 1 (2019): 170. http://dx.doi.org/10.18203/2319-2003.ijbcp20195781.

Full text

Abstract:

Background: Epilepsy is a disease characterized by an enduring predisposition to generate epileptic seizures. Pharmacological therapy is the cornerstone of treatment of epilepsy. In more than 50% patients seizure not controlled with first-line anti-epileptic drugs so added with adjuvant drugs. Therefore adjuvant anti-epileptic drugs play an important role in preventing seizure remission in known epilepsy patients. Observational study was to evaluate the utilisation pattern of adjuvant anti-epileptic drugs and to assess their clinical correlation and observe the adverse effects of the adjuvant

APA, Harvard, Vancouver, ISO, and other styles

32

Farrukh, Alexandra. "DISP-15. FOLIC ACID SUPPLEMENTATION IN WOMEN OF REPRODUCTIVE AGE WITH HISTORY OF INTRACRANIAL TUMOR AND SEIZURES." Neuro-Oncology 26, Supplement_8 (2024): viii150. http://dx.doi.org/10.1093/neuonc/noae165.0588.

Full text

Abstract:

Abstract BACKGROUND Meningiomas and gliomas are the most common intracranial brain tumors. The most common gliomas can be further classified as oligodendroglioma, astrocytoma, ependymoma and glioblastoma. These tumors often cause epilepsy and necessitate the use of anti-seizure medications, posing risks to reproductive-age women due to potential teratogenic effects. The most preferred anti-seizure medications used in pregnancy are levetiracetam and lamotrigine. The American Academy of Neurology advocates folic acid supplementation for women taking anti-seizure medications (ASMs) regardless of

APA, Harvard, Vancouver, ISO, and other styles

33

Zhang, Liang, Hao Yu, Dan Li, Hui Qian, and Yuchao Chen. "Spermatorrhea in a Chinese patient with temporal lobe epilepsy: a case report." Journal of International Medical Research 49, no. 1 (2021): 030006052098281. http://dx.doi.org/10.1177/0300060520982814.

Full text

Abstract:

Epilepsy is a chronic neurological disorder that is characterized by episodes of seizure. Sexual dysfunction has been reported in patients with seizure, which mostly manifests as erectile dysfunction and premature ejaculation in men. In this study, we report the case of a 65-year-old Chinese man with frequent spermatorrhea. Electroencephalography suggested local epilepsy in the left temporal lobe. After treatment with anti-epilepsy drugs, the symptoms disappeared and did not recur. To the best of our knowledge, this is the first reported case of epilepsy-induced spermatorrhea. The symptoms of

APA, Harvard, Vancouver, ISO, and other styles

34

Faraji, Fardin, Farshid Didgar, Afsoon Talaie-Zanjani, and Abolfazl Mohammadbeigi. "Uncontrolled seizures resulting from cerebral venous sinus thrombosis complicating neurobrucellosis." Journal of Neurosciences in Rural Practice 04, no. 03 (2013): 313–16. http://dx.doi.org/10.4103/0976-3147.118780.

Full text

Abstract:

ABSTRACTCerebral venous sinus thrombosis is a rare form of stroke caused by thrombosis in venous sinuses of the brain. In this study, we reported on a patient with venous sinus thrombosis and brucellosis who presented with uncontrolled seizure despite being treated with anti-epileptic drugs at high doses. The case was a 33-year-old woman with a history of controlled complex partial seizure who presented with headache, asthenia, and uncontrolled seizure for one month. She was febrile and a brain CT scan indicated hemorrhagic focus in the left posterior parietal and the temporal lobe. Magnetic r

APA, Harvard, Vancouver, ISO, and other styles

35

Krutoshinskaya, Yana, Kelly Coulehan, Galyna Pushchinska, and Rebecca Spiegel. "The Reciprocal Relationship between Sleep and Epilepsy." Journal of Personalized Medicine 14, no. 1 (2024): 118. http://dx.doi.org/10.3390/jpm14010118.

Full text

Abstract:

The relationship between sleep and epilepsy is bidirectional. Certain epilepsy syndromes predominantly or exclusively manifest during sleep, with seizures frequently originating from non-rapid eye movement (NREM) sleep. Interictal epileptiform discharges observed on electroencephalograms are most likely to be activated during the deep NREM sleep stage known as N3. Conversely, epileptiform discharges, anti-seizure medications (ASMs), as well as other anti-seizure therapies can exert detrimental effects on sleep architecture. Moreover, the co-occurrence of sleep disorders has the potential to ex

APA, Harvard, Vancouver, ISO, and other styles

36

Zavala-Tecuapetla, Cecilia, Hiram Luna-Munguia, María-Leonor López-Meraz, and Manola Cuellar-Herrera. "Advances and Challenges of Cannabidiol as an Anti-Seizure Strategy: Preclinical Evidence." International Journal of Molecular Sciences 23, no. 24 (2022): 16181. http://dx.doi.org/10.3390/ijms232416181.

Full text

Abstract:

The use of Cannabis for medicinal purposes has been documented since ancient times, where one of its principal cannabinoids extracted from Cannabis sativa, cannabidiol (CBD), has emerged over the last few years as a promising molecule with anti-seizure potential. Here, we present an overview of recent literature pointing out CBD’s pharmacological profile (solubility, metabolism, drug-drug interactions, etc.,), CBD’s interactions with multiple molecular targets as well as advances in preclinical research concerning its anti-seizure effect on both acute seizure models and chronic models of epile

APA, Harvard, Vancouver, ISO, and other styles

37

Woo, Min-Hee, Jung-Won Choi, Darda Chung, and Jung-Won Shin. "Anti-LGI1 Antibody Encephalitis Mimicking Jumping Stump Syndrome." Journal of the Korean Neurological Association 38, no. 1 (2020): 46–49. http://dx.doi.org/10.17340/jkna.2020.1.9.

Full text

Abstract:

Jumping stump syndrome is considered to be a peripherally induced movement disorder due to damage to peripheral nerves leading to dystonia or myoclonus. Anti-leucine-rich glioma-inactivated 1 antibody (anti-LGI 1 Ab) encephalitis is clinically characterized with progressive cognitive dysfunction and seizure including facial brachial dystonic seizure. We report a case of a woman with a history of intractable involuntary movement on amputated forearm diagnosed as anti-LGI 1 Ab encephalitis, mimicking symptoms of jumping stump syndrome.

APA, Harvard, Vancouver, ISO, and other styles

38

Moezi, Leila, Siranoush Yahosseini, Akram Jamshizadeh, and Fateme Pirsalami. "Acute Boldine Treatment Induces Anti-convulsant Effects in Mice through its Antioxidant Activity." Drug Research 69, no. 04 (2018): 227–33. http://dx.doi.org/10.1055/a-0659-2478.

Full text

Abstract:

AbstractBoldine is a natural antioxidant that exhibits some important pharmacological properties, which is due to its free radical scavenging effects. And at the same time, reactive oxygen species (ROS) has an important role in pathogenesis of seizure; hence, reducing it via antioxidants like boldine seems to be effective in treating seizure. This study was designed to investigate whether acute treatment with boldine could alter seizures induced by pentylenetetrazole or electroshock in mice. We also evaluated to see if boldine’s antioxidant properties play a role in its anti-convulsant activit

APA, Harvard, Vancouver, ISO, and other styles

39

Yang, Yan, Chao Yuan, Shu-qun Shen, et al. "Autoantibodies to NR2A Peptide of the Glutamate/NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus." Mediators of Inflammation 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/5047898.

Full text

Abstract:

Objective. Seizure disorders are one of the most disabling, life-threatening, and the least understood syndromes associated with neuropsychiatric SLE (NPSLE). N-Methyl-D-aspartate (NMDA) receptors are a subgroup of the glutamate receptor family, whose NR2A subunit was found on neuronal cells (anti-NR2A) in NPSLE patients with different types of epilepsy. The present study was conducted to determine the serum levels of anti-NR2A antibodies in a large group of SLE patients, to investigate the possible correlation between the presence of the NR2A specific antibodies and NPSLE-related seizure diso

APA, Harvard, Vancouver, ISO, and other styles

40

Bisi-Onyemaechi, Adaobi I., Ugo N. Chikani, Ndubuisi A. Uwaezuoke, Ann E. Aronu, and Ngozi C. Ojinnaka. "Serum folate levels in children on long-term anti-seizure medication in a Nigerian tertiary center—Implications for practice and public health." Science Progress 104, no. 4 (2021): 003685042110576. http://dx.doi.org/10.1177/00368504211057680.

Full text

Abstract:

Background: Epilepsy is the most common childhood neurological disorder in Nigeria. Treatment of epilepsy is long-term and sometimes lifelong with anti-seizure medications. There are conflicting reports on the effect of anti-seizure medications on serum folate. There is therefore a need to determine the effect of a commonly used anti-seizure medication's on serum folate levels of children. This would provide an evidence-based consideration for folic acid supplementation in children on anti-seizure medication as has been suggested by some studies. Study objectives: To determine whether serum fo

APA, Harvard, Vancouver, ISO, and other styles

41

Saha, Rupsa, Amrita Chakravorty, Amrita Kumari, Kunal Gupta, Nilanjan Sarkar, and Mainak Chakraborty. "Assessment of Anti-seizure Property of Plumbago indica L. on Zebrafish Model." European Journal of Pharmaceutical Research 3, no. 2 (2023): 1–4. http://dx.doi.org/10.24018/ejpharma.2023.3.2.56.

Full text

Abstract:

The purpose of the current experiment was to determine the anti-convulsant activity of methanolic extract of Plumbago indica L. In a 50 ml beaker 200 mg of the methanolic extract of Plumbago indica L. was dissolved in water containing the experimental zebrafish. After about 20 minutes the fish was administered with pentylenetetrazole (PTZ) (30 mg in 0.5 ml water) intraperitoneally (i.p) to induce seizure in it. The experimental zebrafish immersed in methanolic extract of Plumbago indica L. and administered with PTZ i.p showed clonic seizure-like activity within a few seconds of administering t

APA, Harvard, Vancouver, ISO, and other styles

42

Bahadoran, Ensiyeh, Mohammad Amin Khorasani, Milad Kazemi, and Yazdan Naderi. "Bavachinin attenuates pentylenetetrazol-induced seizures through antioxidant and anti-inflammatory mechanisms in adult male mice." Functional Food Science - Online ISSN: 2767-3146 5, no. 5 (2025): 182–93. https://doi.org/10.31989/ffs.v5i5.1627.

Full text

Abstract:

Background: Epileptic seizures affect approximately 10% of the global population and are associated with morbidity, mortality, and economic burden. Despite the availability of antiepileptic drugs, a lot of patients remain resistant to current treatments. Neuroinflammation and oxidative stress are important contributors to seizure pathophysiology. Bavachinin is a flavonoid derived from Psoralea corylifolia, which has been demonstrated to have antioxidant and anti-inflammatory characteristics. Objectives: This study aimed to evaluate the anticonvulsant potential of bavachinin in a pentylenetetra

APA, Harvard, Vancouver, ISO, and other styles

43

Aldosari, Abdullah Nasser, Ahmed Alghamdi, Ayidh Alharthi, et al. "The Frequency and Precipitating Factors for Breakthrough Seizures in Children with Epilepsy." Journal of Epilepsy Research 13, no. 1 (2023): 13–18. http://dx.doi.org/10.14581/jer.23003.

Full text

Abstract:

Background and Purpose: To determine the common precipitating factors for breakthrough seizures in children with epilepsy.Methods: This retrospective study reviewed the charts of children with epilepsy who were followed up in the pediatric neurology clinic of King Fahad Hospital in Al-Baha region, Saudi Arabia, between January 2015 and August 2022. Children between 1 to 14 years of age who had epilepsy, as per the International League Against Epilepsy definition and received anti-seizure medication with a seizure-free period of at least 2 months before breakthrough seizure episode, were includ

APA, Harvard, Vancouver, ISO, and other styles

44

Fernández, Jhonathan Angel Araujo, Thatiane Cristina de Moura, Sabela Fernández Vila, et al. "Effects of two different peptides on pentylenetetrazole-induced seizures in larval zebrafish." PLOS One 20, no. 4 (2025): e0308581. https://doi.org/10.1371/journal.pone.0308581.

Full text

Abstract:

Epilepsy is a common and severe neurological disease characterized by spontaneous and recurrent seizures. Although anti-seizure treatments are effective for most patients, approximately 30% remain pharmacoresistant. Moreover, uncontrolled seizures are associated with increased health risks and shortened life expectancy in individuals with refractory epilepsy. Preclinical studies play a crucial role in drug discovery, and the zebrafish (Danio rerio) have been successfully employed for this purpose. In this study, we utilized the zebrafish PTZ-induced seizure model to evaluate the effects of two

APA, Harvard, Vancouver, ISO, and other styles

45

Peart, Rodeania, Kaitlyn Melnick, Jean Cibula, et al. "Clinical management of seizures in patients with meningiomas: Efficacy of surgical resection for seizure control and patient-tailored postoperative anti-epileptic drug management." Neuro-Oncology Advances 5, Supplement_1 (2023): i58—i66. http://dx.doi.org/10.1093/noajnl/vdac136.

Full text

Abstract:

Abstract Meningiomas are the most common primary intracranial tumor. They are slow growing and often incidentally found tumors that arise from the arachnoid villi. As they grow, they have a greater likelihood of becoming symptomatic with seizures being one of the most clinically significant symptoms. Seizures are more likely to present as a symptom of larger meningiomas and meningiomas that compress cortical areas particularly those in non-skull base locations. These seizures are often managed medically, utilizing the same anti-seizure medications that are used to treat other causes of epileps

APA, Harvard, Vancouver, ISO, and other styles

46

Zhong, Ning, and Mark Waheed. "Treatment Outcome of Autoimmune Associated Epilepsy (AAE) vs Acute Symptomatic Seizures in Autoimmune Encephalitis (ASSAE)–A Single Center Experience." Neurology 99, no. 23 Supplement 2 (2022): S15.1—S15. http://dx.doi.org/10.1212/01.wnl.0000903144.80173.4c.

Full text

Abstract:

ObjectiveTo assess the seizure treatment outcome in autoimmune encephalitis (AE).BackgroundSeizures due to AE etiology are increasingly recognized. Timely confirmation of autoimmune etiology may lead to improved outcomes by allowing for earlier immunotherapy, which is more effective than anti-seizure medication (ASM). Currently, seizures/epilepsy of autoimmune etiology can be subcategorized as autoimmune associated epilepsy or acute symptomatic seizures in autoimmune encephalitis with varied response to immunotherapy.Design/MethodsThis was a retrospective single center study including patients

APA, Harvard, Vancouver, ISO, and other styles

47

Watkins, Lance, Máire O’Dwyer, and Rohit Shankar. "New anti-seizure medication for elderly epileptic patients." Expert Opinion on Pharmacotherapy 20, no. 13 (2019): 1601–8. http://dx.doi.org/10.1080/14656566.2019.1618272.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

King, Alexa, and Elizabeth E. Gerard. "Updates on Anti-seizure Medication Use in Pregnancy." Current Obstetrics and Gynecology Reports 12, no. 2 (2023): 37–44. http://dx.doi.org/10.1007/s13669-023-00359-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Milovanova, O. A., M. B. Mironov, and E. A. Sandu. "Discontinuation of anti-seizure therapy in epilepsy patients." Epilepsy and paroxysmal conditions 17, no. 1 (2025): 94–100. https://doi.org/10.17749/2077-8333/epi.par.con.2025.227.

Full text

Abstract:

Currently, among one of the most important issues in epileptology is discontinuation of anti-seizure therapy in patients with epilepsy. The article presents contemporary approaches to solving the problem of discontinuation of antiepileptic drugs (AEDs) in patients with epilepsy based on assessing Russian and foreign publications, as well as our clinical experience. A comprehensive analysis of high-priority medical sources on AED discontinuation was carried out, including recommendations proposed by the Italian League Against Epilepsy (2013), practical recommendations for adults and children re

APA, Harvard, Vancouver, ISO, and other styles

50

Kumar, Sandeep, and Rajesh Goel. "Taurine supplementation to anti-seizure drugs as the promising approach to treat pharmacoresistant epilepsy: A pre-clinical study." International Journal of Epilepsy 04, no. 02 (2017): 119–24. http://dx.doi.org/10.1016/j.ijep.2017.07.001.

Full text

Abstract:

AbstractBackground Pharmacoresistance leads to severe, irreversible disabilities and premature death in ∼30% cases of epilepsy despite adequate and appropriate treatment with available anti-seizure drugs (ASDs) without any underlying cause. In light of the large body of evidence which suggests the anti-seizure action of taurine in experimental animals and its wide safety margins in human, supplementation of this inhibitory amino-sulfonic acid to available ASDs seems promising to treat pharmacoresistant epilepsy.Methods We examined the anti-seizure effect of lamotrigine (15 mg/kg), levetiraceta

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!