Academic literature on the topic 'Anti-site defects'

The post-medieval cemetery site Drawsko 1 located in western Poland has yielded several unusual burials with anti-vampire mortuary treatments. There are many possible reasons why these individuals received atypical mortuary treatment, including health problems such as birth defects, disease, and violent injuries. A sample of approximately 300 adult individuals (>18 years) from Drawsko 1, including five “vampire” burials, was analyzed for the presence of various health-related conditions, such as traumatic injuries, infectious disease, stress markers, and dietary deficiency. The deviant and normative burials were compared for the prevalence of each specific condition. Results (Fisher’s exact, p<0.05) suggest that based on these indicators, health-related conditions do not account for the atypical treatment of the “vampire” burials. Instead, deviancy was likely culturally defined and mediated rather than biologically determined.

The 15-year-long resistance to Shell’s pipeline in Rossport, Ireland became a strategic and symbolic site for resistance to neoliberalism and the petroleum industry, combining a community-based environmental justice struggle with a range of left social movements and international ecological activists. The movement faced state violence and media demonisation as well as divisions within the community, tensions between ecological and redistributive priorities and instrumentalisation by some political parties. Despite this the campaign was unusually long, forced substantial changes to state policy and contributed to anti-austerity alliance formation and popular learning processes in resisting fracking, as well as raising the political and financial cost of such projects. Its eventual defeat had more to do with the balance of forces against it than with internal difficulties. This chapter highlights the importance of sustained popular mobilisation, learning through action, counter expertise and alliance formation as key elements needed to bring about a better world.

Objectives: Statins have been proposed as interesting pharmacological treatment for periodontal diseases because of their pleiotropic effect. Statins modulate bone metabolism, immuno-inflammatory complex and bacterial clearance. However, their systemic administration is associated to side effects. Therefore, their local administration has been suggested. The aim of this study was to evaluate the potential pro-regenerative effects of a thermosensitive gel functionalized by lovastatin on Porphyromonas gingivalis elicited inflammation in vitro and bone regeneration in vivo. Methods: Physical and chemical properties of a thermosensitive lovastatin loaded chitosan gel were evaluated. The anti-inflammatory effect of lovastatin was assessed in vitro by RT-qPCR and Elisa. In vivo, a model of calvarial defect was used to confirm the pro-regenerative effect on periodontal wound healing. Results: In vitro, lovastatin was able to decrease TNF-α secretion in P.gingivalis stimulated cells (p<0.05). In vivo, local application of chitosan gel functionalized with lovastatin improved wound healing at calvarial site in comparison with untreated controls and mice treated with systemic statin administration. Conclusions: This study demonstrates the potential regenerative effects of local application of a thermosensitive gel functionalized by lovastatin.

This chapter analyzes the labor movement’s challenge to retail giant Wal-Mart, which in 2002 announced plans to open forty Supercenters in California—threatening to undermine labor standards, and union strength, in the grocery sector. It focuses on the confrontation with Wal-Mart in the separately incorporated city of Inglewood, a historically working-class African American community in South Los Angeles. There, a community-labor coalition, led by LAANE, organized to stop Supercenter development through legislative and legal challenges—a technique known as a “site fight” because it aimed to block Wal-Mart at a specific location. The chapter examines three phases of the fight, tracing how the coalition mobilized law to defeat the Inglewood proposal, design innovative policies to limit Wal-Mart’s entry into the Los Angeles market, and thwart Wal-Mart’s effort to bypass those policies by opening a small-format grocery store in historic Chinatown. In evaluating the campaign, the chapter suggests that the outcome was, in part, a product of Wal-Mart’s political miscalculation: The company’s drive for a Supercenter in Inglewood failed despite evidence of public support, in large measure because of an ill-conceived attempt to gain voter approval through a city initiative that would have completely circumvented the local planning process. Yet Wal-Mart’s defeat was not merely self-inflicted. The company’s miscalculation of the local response to the initiative was politically consequential precisely because there was a sophisticated team of activists and lawyers who used Wal-Mart’s disregard of public input to successfully mobilize community opposition to the Supercenter and build new anti-big-box policy. In that sense, the presence of a political-legal support structure, with experience mounting development-oriented campaigns from the community benefits context, was essential to Wal-Mart’s defeat—strengthening grocery labor standards in Los Angeles going forward.

Several serine protease inhibitorsof plasma inhibit the activated coagulation enzymes but only antithrombin III(AT-III)and heparin cofactor II (HC-II) are implicated in the pathogenesisof the familial thrombosis. Since thefirst publication (1965) many thrombophilic families with reduced AT-III synthesis have been investigated. These studies have proved that the disorder is associated with a high risk forvenous thrombosis and the inheritanceis autosomal dominant. The AT-III activity in the plasma of the affected patients is about 50% of the normalvalue.In recent years the heterogeneity of the i

Guided tissue regeneration focuses on the implantation of a scaffold architecture, which acts as a conduit for stimulated tissue growth. Successful scaffolds must fulfill three basic requirements: provide architecture conducive to cell attachment, support adequate fluid perfusion, and provide mechanical stability during healing and degradation. The first two of these concerns have been addressed successfully with standard scaffold fabrication techniques. In instances where load bearing implants are required, such as in treatment of the spine and long bones, application of these normal design c