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Journal articles on the topic 'Anti tissue-transglutaminase antibodies'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Eremić, Nevena, Mirjana Đerić, and Ljiljana Hadnađev. "Diagnostic Accuracy of IGA Anti-Tissue Transglutaminase Antibody Testing in Celiac Disease." Journal of Medical Biochemistry 31, no. 2 (2012): 100–106. http://dx.doi.org/10.2478/v10011-011-0047-x.

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Diagnostic Accuracy of IGA Anti-Tissue Transglutaminase Antibody Testing in Celiac DiseaseContemporary guidelines for the first-line diagnosis of celiac disease recommend determination of IgA anti-tissue transglutaminase antibodies or IgA antiendomysial antibodies, as well as total serum IgA antibodies. The aim of our study was to assess the validity and clinical significance of serological testing for IgA anti-tissue transglutaminase antibodies in the diagnosis of celiac disease, and to investigate the presence of malabsorption symptoms in celiac patients. IgA anti-tissue transglutaminase ant

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2

Caputo, Ivana, Marilena Lepretti, Agnese Secondo, et al. "Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis." Amino Acids 44, no. 1 (2011): 251–60. http://dx.doi.org/10.1007/s00726-011-1120-y.

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3

Di Tola, M., L. Sabbatella, M. C. Anania, et al. "1P Anti-tissue transglutaminase antibodies in IBD patients." Digestive and Liver Disease 34 (June 2002): A77. http://dx.doi.org/10.1016/s1590-8658(02)90291-4.

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4

McMillan, S. A., and E. Bravi. "Anti-tissue transglutaminase antibodies in IgA deficient sera." Clinical and Applied Immunology Reviews 3, no. 1-2 (2002): 13. http://dx.doi.org/10.1016/s1529-1049(02)00076-4.

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5

Jasim Mohsin, Azhar, and Ali Ibrahim Rahim. "An Association Between Celiac Disease Specific Autoantibody and Infertility in Male: Across Sectional Study." Al-Kufa University Journal for Biology 9, no. 2 (2017): 159–67. http://dx.doi.org/10.36320/ajb/v9.i2.7590.

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Background:The male infertility is considered a health problem ,which attributed to many factors such as genetic ,environmental , previous infections, bad lifestyle and others.these factors have been reported in previous studies.However, this study aimed to determine the effect of anti-tissue transglutaminase antibodies (IgA-tTG)as celiac disease product on the male infertilityObjective: This study was aimed to find out the incidence of celiac disease-specific antibodies, which is known as IgAanti-tissue transglutaminase antibodies (IgA-tTG) in the group of infertile male in Al-Najaf city by a

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6

Segato, S., G. Bisso, L. Ferraris, L. Gianfrate, S. Bonecco, and M. Curzio. "Anti-tissue transglutaminase antibodies (TTGAb): relevance of quantitative assay." American Journal of Gastroenterology 95, no. 9 (2000): 2501. http://dx.doi.org/10.1111/j.1572-0241.2000.02666.x.

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7

Tosco, A., R. Aitoro, R. Auricchio, et al. "Intestinal anti-tissue transglutaminase antibodies in potential coeliac disease." Clinical & Experimental Immunology 171, no. 1 (2012): 69–75. http://dx.doi.org/10.1111/j.1365-2249.2012.04673.x.

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8

Pastore, S., S. Quaglia, F. Ferrara, et al. "Anti-tissue transglutaminase antibodies and infectious diseases in children." Digestive and Liver Disease 40, no. 10 (2008): A64—A65. http://dx.doi.org/10.1016/j.dld.2008.07.214.

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Garcia-Peris, Mónica, Ester Donat Aliaga, María Roca Llorens, Etna Masip Simó, Begoña Polo Miquel, and Carmen Ribes Koninckx. "Anti-tissue transglutaminase antibodies not related to gluten intake." Anales de Pediatría (English Edition) 89, no. 5 (2018): 279–85. http://dx.doi.org/10.1016/j.anpede.2018.01.011.

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10

Picarelli, A., M. Di Tola, L. Sabbatella, A. Spadaro, M. L. Sorgi, and E. Taccari. "Anti-tissue transglutaminase antibodies in spondyloarthropathy: A marker of tissue lesion." Digestive and Liver Disease 33 (November 2001): A8. http://dx.doi.org/10.1016/s1590-8658(01)80187-0.

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Balasa, Adriana Luminita, Cristina Maria Mihai, Tatiana Chisnoiu, and Corina Elena Frecus. "Atypical presentations of celiac disease." ARS Medica Tomitana 22, no. 3 (2016): 181–85. http://dx.doi.org/10.1515/arsm-2016-0030.

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Abstract In this study we evaluated the association of celiac disease in 81 children with autoimmune disease and genetic syndromes over a two years periods (January 2014 to July 2016) in Pediatric Clinic in Constanta. Because the extraintestinal symptoms are an atypical presentation of celiac disease we determined in these children the presence of celiac disease antibodies: Anti-tissue Transglutaminase Antibody IgA and IgA total serum level as a screening method followeds in selective cases by Anti-tissue Transglutaminase Antibody IgG, anti-endomysial antibodies, deamidated gliadin antibodies

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12

Mohammed, Lana, and Yousif Ahmed. "Correlation between auto-immune diseases and type 1 diabetes mellitus in the pediatric age group in Erbil city." Zanco Journal of Medical Sciences 28, no. 1 (2024): 85–94. http://dx.doi.org/10.15218/zjms.2024.009.

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Background and objective: Type-1 diabetes mellitus is the most common chronic endocrine disorder of childhood and adolescence and is characterized by immune-mediated destruction of pancreatic cells, which has been proven to be correlated with and increase the risk of developing autoimmune thyroid disease, celiac disease, Addison’s disease, and further autoimmune diseases. The aim of this study is to evaluate the prevalence of autoimmune disease-related markers in type 1 diabetes mellitus in children and adolescents in Erbil city. Methods: One hundred children and adolescents with type 1 diabet

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13

Oussama, Aazzane, Bazhar Hasnaa, and Fellah Hassan. "Evaluation of the Immunodot Technique Compared to the Elisa Technique for the Detection of IgA Antibodies to Tissue Transglutaminase." International Journal of Innovative Science and Research Technology (IJISRT) 9, no. 12 (2025): 1819–23. https://doi.org/10.5281/zenodo.14576664.

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Celiac disease (CD) is a chronic autoimmune enteropathy characterized by intestinal villous atrophy secondary to gluten ingestion. In the biological diagnosis of CD, serology includes, among other tests, the search for IgA anti-tissue transglutaminase antibodies (IgA anti-tTG). Various techniques are employed, including ELISA and Immunodot. The objective of this work is to evaluate the diagnostic performance of the Immunodot  test compared to the ELISA test for detecting IgA anti- tTG antibodies in the serum of patients with CD and  controls. This is a comparative study of the Immuno

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14

Balamtekin, Necati, Harun Erdal, Emira Gençkardeşler, and Melike Arslan. "Reliability of anti-tissue transglutaminase antibodies in children with malnutrition." Scandinavian Journal of Gastroenterology 56, no. 4 (2021): 378–81. http://dx.doi.org/10.1080/00365521.2021.1882554.

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15

PASTORE, S., S. QUAGLIA, F. FERRARA, S. MARTELOSSI, A. VENTURA, and T. NOT. "S1254 Anti-Tissue Transglutaminase Antibodies and Infectious Diseases in Children." Gastroenterology 134, no. 4 (2008): A—211—A—211. http://dx.doi.org/10.1016/s0016-5085(08)60976-2.

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16

Di Tola, M., L. Sabbatella, T. Di Cello, et al. "Anti-tissue transglutaminase antibodies: a general intestinal lesions-associated event?" Digestive and Liver Disease 33 (November 2001): A99. http://dx.doi.org/10.1016/s1590-8658(01)80546-6.

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17

Lomas, Harriet, India Rees, and Nadim Haboubi. "Unusually high titres of anti-tissue transglutaminase antibodies in monozygotic twins." Journal of the Royal College of Physicians of Edinburgh 52, no. 1 (2022): 39–41. http://dx.doi.org/10.1177/14782715221088971.

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Anti-tissue transglutaminase antibodies (anti-tTG) play a vital role in the screening process for coeliac disease (CD). Levels above 30 U/ml suggest a possible diagnosis of CD, prompting further investigation, usually by taking a duodenal biopsy. We report an unusual case of 39-year-old male twins, one presenting with iron deficiency anaemia and the other asymptomatic, with anti-tTG antibodies of >4,965.5 U/ml, an extraordinary level. A duodenal biopsy confirmed a diagnosis of CD and following the adoption of a gluten-free diet, anti-tTG levels were found to decrease back to normal levels.

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18

Muzslay, Eszter, Eszter Hámory, Vivien Herczeg, et al. "A szöveti antitranszglutamináz átmeneti emelkedése coeliakiával nem társult I-es típusú cukorbeteg gyermekekben." Orvosi Hetilap 162, no. 48 (2021): 1924–30. http://dx.doi.org/10.1556/650.2021.32287.

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Összefoglaló. Bevezetés: Az 1-es típusú diabetes mellitus és a coeliakia gyakori társulása jól ismert. Néhány tanulmány beszámol átmeneti antitranszglutamináz-emelkedésről 1-es típusú diabeteses betegekben, akiknél az emelkedett antitestszint gluténmentes diéta bevezetése nélkül normalizálódik. Célkitűzés: Kutatásunk során az átmeneti antitranszglutamináz-emelkedés gyakoriságának meghatározását tűztük ki célul. További célunk volt a coeliakia gyakoriságának megállapítása 1-es típusú diabetesszel gondozott betegeink között. Módszer: A Semmelweis Egyetem I. Gyermekgyógyászati Klinikáján 1-es típ

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19

Sugai, Emilia, Hui Jer Hwang, Horacio Vázquez, et al. "New Serology Assays Can Detect Gluten Sensitivity among Enteropathy Patients Seronegative for Anti–Tissue Transglutaminase." Clinical Chemistry 56, no. 4 (2010): 661–65. http://dx.doi.org/10.1373/clinchem.2009.129668.

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Abstract Background: Some patients with celiac disease (CD) may be seronegative with the commonly used test for IgA anti–tissue transglutaminase (anti-tTG) antibodies. Our aim was to explore whether newer assays incorporating synthetic deamidated gliadin-related peptides (DGPs) or other TG isoenzymes as antigen are useful for detecting gluten sensitivity in IgA anti-tTG–seronegative patients. Methods: We assayed serum samples obtained at diagnosis from (a) anti-tTG–seronegative patients with a CD-like enteropathy (n = 12), (b) skin biopsy–proven dermatitis herpetiformis (DH) patients (n = 26),

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20

Nicoletti, A., F. Patti, S. Lo Fermo, et al. "Frequency of celiac disease is not increased among multiple sclerosis patients." Multiple Sclerosis Journal 14, no. 5 (2008): 698–700. http://dx.doi.org/10.1177/1352458507087268.

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We evaluated the presence of IgA and IgG celiac disease–related antibodies in a sample of 217 patients with multiple sclerosis (MS) and in a sample of 200 controls not affected by neurological disorders. None of the 217 patients with MS presented IgG and IgA anti-gliadin, anti-endomysial antibodies, anti-tissue transglutaminase and anti-reticulin, whereas only one of the selected controls presented specific antibodies; this subject resulted to be effectively affected by celiac disease. Our data did not show an increased frequency of celiac disease among patients with MS.

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21

Stenberg, Reidun, Charlotte Dahle, Eva Lindberg, and Jens Schollin. "Increased Prevalence of Anti-gliadin Antibodies and Anti-tissue Transglutaminase Antibodies in Children With Cerebral Palsy." Journal of Pediatric Gastroenterology and Nutrition 49, no. 4 (2009): 424–29. http://dx.doi.org/10.1097/mpg.0b013e31819a4e52.

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22

M.Sc., Zahraa Abbass Qasim, and Hawraa Abdul ameer Ali Al-Dahhan Prof.Dr. "Assessment the Levels of Antibodies (Anti-TTG and Anti-AGA) in the Serum of Patients with Celiac Disease." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 07 (2024): 595–602. https://doi.org/10.5281/zenodo.12620483.

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Celiac disease (CD) is an autoimmune disorder defined by distinct serological and histological alterations induced by the consumption of gluten in genetically predisposed individuals. This study aims to assess the levels of antibodies (anti - tTG and anti - AGA) as  in the serum of patients with celiac disease. This case-control study involved 85 celiac disease patients (35 males and 50 females) recruited between July 2023 and December 2023. Samples were collected from the Internal Medicine Unit at Al-Sadder Medical City and the Specialized Hospital for Gastroenterology and Hepatology in

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23

Barker, Collin, Gareth Jevon, and Thomas Mock. "ONLY HIGH TITRE ANTI-TISSUE TRANSGLUTAMINASE ANTIBODIES CONSISTENTLY PREDICT CELIAC DISEASE." Journal of Pediatric Gastroenterology and Nutrition 43, no. 4 (2006): E43. http://dx.doi.org/10.1097/00005176-200610000-00120.

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24

Basso, Daniela, Graziella Guariso, Michela Fasolo, et al. "A New Indirect Chemiluminescent Immunoassay to Measure Anti–tissue Transglutaminase Antibodies." Journal of Pediatric Gastroenterology and Nutrition 43, no. 5 (2006): 613–18. http://dx.doi.org/10.1097/01.mpg.0000239739.09983.38.

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25

Mata, S., D. Renzi, F. Pinto, and A. Calabro. "Anti-tissue transglutaminase IgA antibodies in peripheral neuropathy and motor neuronopathy." Acta Neurologica Scandinavica 114, no. 1 (2006): 54–58. http://dx.doi.org/10.1111/j.1600-0404.2006.00602.x.

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26

Picarelli, Antonio, Marco Di Tola, Luigi Sabbatella, et al. "Anti-Tissue Transglutaminase Antibodies in Arthritic Patients: A Disease-specific Finding?" Clinical Chemistry 49, no. 12 (2003): 2091–94. http://dx.doi.org/10.1373/clinchem.2003.023234.

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27

Twito, Orit, Yonatan Shapiro, Aviva Golan-Cohen, Yoav Dickstein, Rosane Ness-Abramof, and Menachem Shapiro. "Anti-thyroid antibodies, parietal cell antibodies and tissue transglutaminase antibodies in patients with autoimmune thyroid disease." Archives of Medical Science 14, no. 3 (2018): 516–20. http://dx.doi.org/10.5114/aoms.2016.58743.

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28

Castaño, Luis, Elisabeth Blarduni, Lourdes Ortiz, et al. "Prospective Population Screening for Celiac Disease: High Prevalence in the First 3 Years of Life." Journal of Pediatric Gastroenterology and Nutrition 39, no. 1 (2004): 80–84. http://dx.doi.org/10.1002/j.1536-4801.2004.tb12296.x.

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ABSTRACTBackground:Celiac disease (CD) is an autoimmune enteropathy that develops in genetically susceptible individuals exposed to gliadin. Early diagnosis of CD may reduce the risk of complications, and several studies have related the duration of gluten exposure to the risk of other autoimmune diseases. It has been proposed that silent CD be diagnosed as soon as possible to avoid potential complications.Objectives:The purpose of this study was to determine the prevalence of CD among children less than 3 years and to provide treatment to those patients diagnosed with CD.Patients and Methods:

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Dehghani, S. M., M. H. Anbardar, I. Shahramian, et al. "Duration of anti-tissue transglutaminase normalization after starting a gluten-free diet in children with celiac disease." Voprosy detskoj dietologii 20, no. 6 (2022): 33–40. http://dx.doi.org/10.20953/1727-5784-2022-6-33-40.

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The aim of the present study was to investigate the time required for the normalization of anti-tissue transglutaminase antibodies IgA (anti-TTG IgA) after starting a gluten-free diet (GFD) in children with celiac disease (CeD). This study included 59 children under 18 years of age with a confirmed diagnosis of CeD referred to Imam Reza Clinic affiliated with Shiraz University of Medical Sciences. All children were divided into two groups, including those with either <180 or >180 U/mL anti-TTG IgA levels. The titer of anti-TTG IgA was checked after the start of GFD. Data analysis was per

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30

Velikova, Tsvetelina, Georgi Vasilev, Russka Shumnalieva, et al. "Autoantibodies related to ataxia and other central nervous system manifestations of gluten enteropathy." World Journal of Clinical Cases 12, no. 12 (2024): 2031–39. http://dx.doi.org/10.12998/wjcc.v12.i12.2031.

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Gluten ataxia and other central nervous system disorders could be linked to gluten enteropathy and related autoantibodies. In this narrative review, we focus on the various neuro-logical manifestations in patients with gluten sensitivity/celiac disease, immunological and autoimmune mechanisms of ataxia in connection to gluten sensitivity and the autoantibodies that could be used as a biomarker for diagnosing and following. We focused on the anti-gliadin antibodies, antibodies to different isoforms of tissue transglutaminase (TG) (anti-TG2, 3, and 6 antibodies), anti-glycine receptor antibodies

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Esposito, C., F. Paparo, I. Caputo, et al. "Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ." Gut 51, no. 2 (2002): 177–81. http://dx.doi.org/10.1136/gut.51.2.177.

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32

Pãun, Angela Gabriela, Simona Popescu, Alisa Ioana Ungureanu, et al. "Anti-Tissue-Transglutaminase IgA Antibodies Presence Determination Using Electrochemical Square Wave Voltammetry and Modified Electrodes Based on Polypyrrole and Quantum Dots." Biosensors 15, no. 1 (2025): 42. https://doi.org/10.3390/bios15010042.

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A novel electrochemical detection method utilizing a cost-effective hybrid-modified electrode has been established. A glassy carbon (GC) modified electrode was tested for its ability to measure electrochemical tTG antibody levels, which are essential for diagnosing and monitoring Celiac disease (CD). Tissue transglutaminase protein biomolecules are immobilized on a quantum dots-polypyrrole nanocomposite in the improved electrode. Initial, quantum dots (QDs) were obtained from Bombyx mori silk fibroin and embedded in polypyrrole film. Using carbodiimide coupling, a polyamidoamine (PAMAM) dendri

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Shahzad, Amir, Abdul Aziz Sahto, and Miss Samina. "FREQUENCY OF CELIAC DISEASE." Professional Medical Journal 23, no. 07 (2016): 812–16. http://dx.doi.org/10.29309/tpmj/2016.23.07.1644.

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Objectives: The aim behind this study was to determine the frequency of Celiacdisease in patients presenting with Iron deficiency anemia at tertiary care hospital. StudyDesign: Descriptive cross sectional hospital based study. Setting: Non-probability consecutivesampling technique in a department of medicine at Medical Unit II, People’s Medical University,Shaheed Benazeerabad. Period: Six months from 26th October 2014 to 25th April 2015. Patientsand Methods: A standard sample bottle was used to collect the blood sample from the peripheralvein followed by testing for Anti-tissue transglutaminas

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Schwertz, Elke, Franka Kahlenberg, Ulrich Sack, et al. "Serologic Assay Based on Gliadin-Related Nonapeptides as a Highly Sensitive and Specific Diagnostic Aid in Celiac Disease." Clinical Chemistry 50, no. 12 (2004): 2370–75. http://dx.doi.org/10.1373/clinchem.2004.036111.

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Abstract Background: Celiac disease (CD) is induced by wheat gliadins and related cereal proteins. Anti-gliadin antibodies (AGAs) are present in the serum of CD patients, but these antibodies have lower diagnostic specificity and sensitivity than autoantibodies [anti-endomysium antibodies (AEmAs) and anti-tissue transglutaminase antibodies (AtTGAs)]. Recently, AGAs from CD patients were found to recognize deamidated gliadin peptides, probably formed by the action of tissue transglutaminase. Methods: We synthesized several gliadin peptides and their glutamine-glutamic acid-substituted counterpa

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Vecchi, M. D. M., C. Folli, M. F. Donato, S. Formenti, E. Arosio, and R. de Franchis. "High Rate of Positive Anti-Tissue Transglutaminase Antibodies in Chronic Liver Disease." Scandinavian Journal of Gastroenterology 38, no. 1 (2003): 50–54. http://dx.doi.org/10.1080/00365520310000438.

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DIPPER, C. R., S. MAITRA, R. THOMAS, et al. "Anti-tissue transglutaminase antibodies in the follow-up of adult coeliac disease." Alimentary Pharmacology & Therapeutics 30, no. 3 (2009): 236–44. http://dx.doi.org/10.1111/j.1365-2036.2009.04039.x.

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Ivanovski, Petar Ilija, Ivan P. Ivanovski, and Rade Sedlarevic. "Are xenogeneic anti-tissue transglutaminase antibodies the holy grail for celiac patients?" Medical Hypotheses 69, no. 6 (2007): 1257–60. http://dx.doi.org/10.1016/j.mehy.2007.04.003.

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Fabiani, Elisabetta, Egiziano Peruzzi, Clementina Rondina, et al. "Anti-human IgA tissue transglutaminase antibodies as screening test for coeliac disease." Gastroenterology 124, no. 4 (2003): A660. http://dx.doi.org/10.1016/s0016-5085(03)83344-9.

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Memar, Bahram, Maryam Naghavi, Hassan Vosoughinia, et al. "Prevalence of IgA Anti-tissue Transglutaminase Antibody in a Cohort of Iranians Patients with Inflammatory Bowel Disease." Journal of Coloproctology 43, no. 04 (2023): e280-e285. http://dx.doi.org/10.1055/s-0043-1776888.

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Abstract Background and Aims Some studies have reported the coexistence of inflammatory bowel disease (IBD) and celiac disease (CD). However, the prevalence of anti-tissue transglutaminase antibodies (IgA and IgG) and their screening value in patients with IBD is not yet clear. This study aimed to assess the prevalence of IgA anti-tTG and its potential correlation with disease status in patients with IBD. Materials and Methods This cross-sectional study was conducted on 110 patients with confirmed IBD diagnosis at Ghaem Hospital, Mashhad, Iran. For each patient, all demographic and clinical da

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40

Talluri, Jyothsna, Siddesh V. Besur, and Siva K. Talluri. "Sa1267 Characteristics of Patients With Anti-Tissue Transglutaminase Antibodies and Anti-Endomysial Antibodies: Data From NHANES 2009-2010." Gastroenterology 144, no. 5 (2013): S—246—S—247. http://dx.doi.org/10.1016/s0016-5085(13)60873-2.

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Kumari, A1 6# Singh I2# Verma A1 3. Singh I1 Hooda U1 Faruq M4 Swarup V2 Garg A5 Ahuja V1 Makharia G1* and Srivastava A2*. "Anti-Gliadin and Anti-Tissue Transglutaminase Antibodies in the Serum of Patients with Cerebellar Ataxia." International Clinical and Medical Case Reports Journal 4, no. 5 (2025): 1–12. https://doi.org/10.5281/zenodo.15365057.

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<strong>1.1. Background:</strong> Cerebellar ataxia is a heterogeneous group of disorders which can be familial or sporadic. Sensitivity to gluten has been implicated in the pathogenesis of sporadic cerebellar ataxia. Since there is a paucity of data on prevalence of gluten sensitivity in ataxia patients from Asian countries, we screened well-characterized progressive cerebellar ataxia patients for the presence of gluten sensitivity. <strong>1.2. Materials and Methods:</strong> A cohort of 192 familial and sporadic patients with progressive cerebellar ataxia, were screened for the presence of

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42

Riseh, S. "The Relationship between Thyroid Hormones, Antithyroid Antibodies, Anti-Tissue Transglutaminase and Anti-Gliadin Antibodies in Patients with Hashimoto's Thyroiditis." Acta Endocrinologica (Bucharest) 13, no. 2 (2017): 174–79. http://dx.doi.org/10.4183/aeb.2017.174.

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43

Korponay-Szabó, I. R., S. Sulkanen, T. Halttunen, et al. "COMPLETE OVERLAPPING OF TISSUE STAINING PATTERNS OF ANTI-TRANSGLUTAMINASE ANTIBODIES AND COELIAC DISEASE-SPECIFIC IgA ANTIBODIES." Journal of Pediatric Gastroenterology &amp Nutrition 26, no. 5 (1998): 553. http://dx.doi.org/10.1097/00005176-199805000-00077.

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44

Korponay‐Szabó, I. R., S. Sulkanen, T. Halttunen, et al. "COMPLETE OVERLAPPING OF TISSUE STAINING PATTERNS OF ANTI‐TRANSGLUTAMINASE ANTIBODIES AND COELIAC DISEASE‐SPECIFIC IgA ANTIBODIES." Journal of Pediatric Gastroenterology and Nutrition 26, no. 5 (1998): 553. http://dx.doi.org/10.1002/j.1536-4801.1998.tb00949.x.

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45

Hansson, Tony, Ingrid Dahlbom, Jeanette Hall, et al. "Antibody Reactivity Against Human and Guinea Pig Tissue Transglutaminase in Children with Celiac Disease." Journal of Pediatric Gastroenterology and Nutrition 30, no. 4 (2000): 379–84. http://dx.doi.org/10.1002/j.1536-4801.2000.tb02756.x.

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ABSTRACTBackground:Highly discriminatory markers for celiac disease are needed to identify children with early mucosal lesions. The purposes of this study were to evaluate the clinical potential of circulating anti‐tissue transglutaminase (tTG) immunoglobulin (Ig)A antibodies in the diagnosis of childhood celiac disease and to investigate the extent of autoreactivity of these antibodies.Methods:Included in this retrospective study were samples from 22 children with biopsy‐verified celiac disease, 23 control subjects with disease, and 22 healthy control subjects without any known gastrointestin

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Hill, PG, and SA McMillan. "Anti-tissue transglutaminase antibodies and their role in the investigation of coeliac disease." Annals of Clinical Biochemistry 43, no. 2 (2006): 105–17. http://dx.doi.org/10.1258/000456306776021599.

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Arguelles-Grande, Carolina, Gary L. Norman, Govind Bhagat, and Peter H. R. Green. "Hemolysis Interferes with the Detection of Anti–Tissue Transglutaminase Antibodies in Celiac Disease." Clinical Chemistry 56, no. 6 (2010): 1034–36. http://dx.doi.org/10.1373/clinchem.2009.141242.

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Bizzaro, N., M. Tampoia, D. Villalta, et al. "Low specificity of anti-tissue transglutaminase antibodies in patients with primary biliary cirrhosis." Journal of Clinical Laboratory Analysis 20, no. 5 (2006): 184–89. http://dx.doi.org/10.1002/jcla.20130.

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Pavelescu, Luciana Alexandra, Ileana Delia Sabau, Gabriela Sanda-Dira, Alexandra Antonela Iacata, and Antoanela Curici. "Serological, Genetic, and Biochemical Insights into Celiac Disease Diagnosis and Vitamin D Deficiency in Romanian Children: A Comprehensive Cohort Study." International Journal of Molecular Sciences 26, no. 13 (2025): 6251. https://doi.org/10.3390/ijms26136251.

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Abstract:

A large cohort of Romanian children suspected of celiac disease (CD) received comprehensive evaluation through this study regarding serological, genetic, and biochemical markers. This study investigated the relationships between anti-tissue transglutaminase (anti-tTG), anti-endomysium antibodies (EMAs), anti-gliadin deamidated (DGP) antibodies, and HLA genotyping. A strong association was observed between high anti-tTG IgA titers (>100 U/mL) and EMA IgA positivity, with a 95% concordance rate. Furthermore, anti-tTG IgA positive correlated with a significant prevalence of DGP antibodies, sug

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Dahlbom, Ingrid, Martin Olsson, Nahal Kazemi Forooz, Anders G. Sjöholm, Lennart Truedsson, and Tony Hansson. "Immunoglobulin G (IgG) Anti-Tissue Transglutaminase Antibodies Used as Markers for IgA-Deficient Celiac Disease Patients." Clinical Diagnostic Laboratory Immunology 12, no. 2 (2005): 254–58. http://dx.doi.org/10.1128/cdli.12.2.254-258.2005.

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ABSTRACT The role of immunoglobulin A (IgA) anti-tissue transglutaminase antibodies (IgA-tTG) as predictors of untreated celiac disease (CoD) is well documented, and the presence and levels of these antibodies are most accurately monitored with native or recombinant human antigens. However, IgA-deficient CoD patients are not identified by IgA serology, and conflicting results concerning the diagnostic validity of IgG antibodies against gliadin (IgG-AGA), endomysium (IgG-EmA), and tTG (IgG-tTG) have been reported. The aim of the present study was to evaluate the utility of IgG-tTG for the detec

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