Relevant bibliographies by topics / Anti-Tubercular Drugs (AKT)

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Academic literature on the topic 'Anti-Tubercular Drugs (AKT)'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Anti-Tubercular Drugs (AKT)"

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Kale, Nandkishor. "TO STUDY EFFICACY OF JIVANTYADI GHRIT AS ADD-ON TREATMENT IN PTB TREATING WITH AKT (DOTS) REGIMEN." Journal of Ayurvedic Herbal and Integrative Medicine 2, no. 1 (2022): 1–12. http://dx.doi.org/10.29121/j-ahim.v2.i1.2022.17.

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Background: Patients of Pulmonary Tuberculosis continued to be suffering from the adverse effects of the Anti-tubercular drugs even though they are used efficiently, the rate of infection of pulmonary tuberculosis is not satisfactory under control. Hence the present study was conducted, to study the efficacy and to minimize the side effects of present therapy (DOTs) by using along with Ayurveda formulation. Objectives: To Study the efficacy of Jivantyadi Ghrit as Add-on treatment in PTB treating with AKT (DOTs) regimen. Materials and Methods: It was an open labelled, controlled clinical study.
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Shetty, SS, and CK Shetty. "Spectrum of Surgical Presentation of Eosinophilic Enteritis: A Case Series." International Journal of Surgery and Research 2, no. 2 (2015): 8–12. https://doi.org/10.19070/2379-156X-150003.

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Eosinophilic enteritis is a rare disorder presenting mostly with diarrhea, malabsorption, abdominal pain, weight loss and hypersensitivity. Surgical manifestation of eosinophilic gastrointestinal disorders depends on the site and extent of involvement. In our case series of four patients two of them had ileocaecal masses with recurrent subacute intestinal obstruction with past history of intake of anti-tubercular drugs for 9 months. On histopathological examination both of them proved to have eosinophilic enterocolitis. Thus it is a clinical dilemma to differentiate between
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3

Prajapati, Anil Kumar, Pratiksha Patil, and Sneha Joshi. "A review on plants possesses anti tubercular activity." Journal of Preventive Medicine and Holistic Health 9, no. 2 (2023): 50–56. http://dx.doi.org/10.18231/j.jpmhh.2023.012.

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Tuberculosis is an infectious disease condition that mainly affects the lungs, and the responsible bacteria is . Over 4,000 people each day die from this disease, which also claims 1.2–1.5 million lives annually and has infected 1.7–2 billion individuals globally. The literature review was conducted by studying the research papers and review articles concentrating on the traditional plants having “Antituberculosis activity or anti-mycobacterial activity”, in electronic databases like PubMed, Science Direct, Scopus, and Google Scholar. The available synthetic therapy for tuberculosis treatment
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4

Ahmed Elkanzi, Nadia Ali. "Synthesis and Biological Activities of Some Pyrimidine Derivatives: A Review." Oriental Journal Of Chemistry 36, no. 6 (2020): 1001–15. http://dx.doi.org/10.13005/ojc/360602.

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Nitrogen containing synthetically and biologically important heterocyclic ring system namely pyrimidine possess both biological and pharmacological activities, and defend as aromatic six heterocyclic with 1and 3 nitrogen atom in ring. Preparation of pyrimidine via different methods offer its importance in fields of medicinal chemistry and Chemistry. Pyrimidines and their derivatives act as anti-inflammatory, anti-malaria, anti-tumor, cardiovascular agents, anti-neoplastic, anti-tubercular, anti- HIV, diuretic ,anti-viral, anti-microbial, ,analgesic .This review give light up on biological and
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5

M., Prashanthi Evangelin *. "A CRITICAL REVIEW ON SYNTHETIC PATHWAY OF BENZOFURANS." Journal of Pharma Research 8, no. 7 (2019): 513–15. https://doi.org/10.5281/zenodo.3357207.

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<strong><em>ABSTRACT</em></strong> <em>&ldquo;</em><strong><em>B</em></strong><em>enzofuran&rdquo; a heterocyclic moiety which act as a lead molecule for several biologically active compounds. Besides, benzofuran derivatives show several activities like anti-tubercular, anti-tumor, anti plasmodial, cytotoxic and herbicidal. So, they found a variety of applications in manufacturing drugs as pharmacological agents and used in other fields of agriculture and organic chemistry. They are present as natural products which were isolated from Machilus glaucescens, Krameria ramosissima and Zanthoxylum
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Somani, R., P. Dubey, and S. Zine. "MICROWAVE ASSISTED SYNTHESIS OF BIPHENYL BASED SCHIFF’S BASES AND THEIR ANTIMICROBIAL EVALUATION." INDIAN DRUGS 55, no. 03 (2018): 13–18. http://dx.doi.org/10.53879/id.55.03.11218.

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Schiff’s base constitutes a significant class of compounds for new drug development. They are widely used for industrial purposes and also exhibit a broad range of biological activities. The search for Schiff’s base containing compounds with more selective activity and lower side effects continues to be an active area of argument examination in medicinal chemistry. The biphenyl molecule consists of two connected phenyl rings. Biphenyl ring scaffolds are fairly non-reactive in nature. They enhance the log-P values; increase the tropical polar surface area (TPSA) of the molecule, act as hydropho
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7

GL, Balasubramani, Rinky Rajput, Manish Gupta, et al. "Structure-based drug repurposing to inhibit the DNA gyrase of Mycobacterium tuberculosis." Biochemical Journal 477, no. 21 (2020): 4167–90. http://dx.doi.org/10.1042/bcj20200462.

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Drug repurposing is an alternative avenue for identifying new drugs to treat tuberculosis (TB). Despite the broad-range of anti-tubercular drugs, the emergence of multi-drug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis (Mtb) H37Rv, as well as the significant death toll globally, necessitates the development of new and effective drugs to treat TB. In this study, we have employed a drug repurposing approach to address this drug resistance problem by screening the drugbank database to identify novel inhibitors of the Mtb target enzyme, DNA gyrase. The compounds w
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8

Mishra, Abhinav Prasoon, Ankit Bajpai, and Awani Kumar Rai. "1,4-Dihydropyridine: A Dependable Heterocyclic Ring with the Promising and the Most Anticipable Therapeutic Effects." Mini-Reviews in Medicinal Chemistry 19, no. 15 (2019): 1219–54. http://dx.doi.org/10.2174/1389557519666190425184749.

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: Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal chemistry. Among all of the heterocyclic scaffolds, 1,4-Dihydropyridine (1,4-DHP) is one of the most important heterocyclic rings that possess prominent therapeutic effects in a very versatile manner and plays an important role in synthetic, medicinal, and bioorganic chemistry. The main aim of the study is to review and encompass relevant studies related to 1,4-DHP and excellent therapeutic benefits of its derivatives. An extensive review of Pubmed-Medline, Embase and Lancet’s published articles was done to
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9

Mudegoudara, Lingaraja, K. Shashibushan J. Venugopal, and Naik Shankar. "A Study of Liver Function Tests Abnormalities in Tuberculosis Patients Under RNTCP-DOTS, VIMS Bellary." PJSR 8, no. 1 (2015): 28–33. https://doi.org/10.5281/zenodo.8249661.

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A prospective study was conducted among 100 patients selected from amongst those who were registered in the Revised national tuberculosis control programme (RNTCP) cell of VIMS Hospital Bellary from January 2012 to the end of June 2012 and they were followed up to December 2012. The purpose of the study was to evaluate the incidence of drug induced hepatotoxicity (DIH) in proved cases of pulmonary tuberculosis in patients on short term regimen of anti--tuberculosis therapy (ATT) in and around Bellary locality. To study about the predisposing factors for DIH. To study and evaluate the clinical
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10

Gunapati, Rama Mohan Reddy Usha Kiran Prayaga and Sekhar Babu Bandar. "STEVENS-JOHNSON SYNDROME (SJS) AND TOXIC EPIDERMAL NECROLYSIS (TEN) ASSOCIATED WITH ANTI-TUBERCULAR DRUGS: A CASE REPORT." June 21, 2022. https://doi.org/10.5281/zenodo.6802456.

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<strong>Introduction:</strong>&nbsp;Steven-Johnson syndrome (SJS) is an acute reaction that typically involves the skin and mucous membranes which are characterized by damage and flaking of the skin, accompanied by pain, and can cause death. Toxic epidermal necrolysis (TEN) is a rare, life-threatening skin reaction usually caused by medication,which is characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and/or death.SJS and TEN are some of the rare side-effects from Drugs used in Anti-Tubercu
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Book chapters on the topic "Anti-Tubercular Drugs (AKT)"

1

Mohan Sahoo, Biswa, Bera Venkata Varaha Ravi Kumar, Krishna Chandra Panda, et al. "Isoxazole Derivatives as Potential Pharmacophore for New Drug Development." In Frontiers in Medicinal Chemistry. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815165043123100004.

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Isoxazoles are five-membered aromatic heterocyclic compounds in which oxygen and nitrogen atoms are present at positions 1 and 2 of the ring system. Isoxazole derivatives play a vital role due to their diverse biological activities, such as antimicrobial, antifungal, anti-viral, anti-tubercular, anti-epileptic, anti-diabetic, anticancer, anthelmintic, antioxidant, antipsychotic, antimalarial, analgesic, anti-inflammatory, etc. Isoxazole scaffold is present in various drug molecules, such as leflunomide (antirheumatic), valdecoxib (non-steroidal anti-inflammatory drug), and zonisamide (anti-con
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2

Appetecchia, Federico, Mariangela Biava, and Giovanna Poce. "Natural Flavonoid and Chalcone Scaffolds as Leads for Synthetic Antitubercular Agents." In Flavonoids and Phenolics. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079098122010008.

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Tuberculosis is a leading cause of mortality and morbidity worldwide, claiming 1.2 million deaths (including 208 000 people with HIV) and 10 million new cases in 2019. Current treatment suffers from significant shortcomings such as length, dosage regimen, toxicity, and resistance development to currently used medicines. The emergence of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis is a major concern in controlling the disease. Therefore, there is an urgent need for new antitubercular drugs that are active against resistant strains, less toxic, and that act upon
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