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Dissertations / Theses on the topic 'ANTIBACTERIAL AND ANTIFUNGAL ASSAY'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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1

Dascalu, Anca-Elena. "Bioantibio, biosourced antibacterial and antifungal molecules." Thesis, Lille, 2019. http://www.theses.fr/2019LILUS052.

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Le manque d'innovations thérapeutiques a récemment atteint un niveau critique par rapport aux traitements antibiotiques. Cette question, corrélée à l’apparition de bactéries multirésistantes, a mis en évidence la nécessité de nouvelles approches pour la découverte d’antibiotiques innovants. En conséquence, le projet BIOANTIBIO a été proposé.Les deux principales applications initialement envisagées pour les composés les plus actifs sont:• Additifs pour la formulation de matériaux innovants (par exemple, peintures et revêtements) afin de garantir leur durabilité en stockage (en collaboration ave

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2

Coventry, Emma. "Antibacterial and antifungal properties of neem (Azadirachta indica A. Juss)." Thesis, University of Aberdeen, 1997. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU100079.

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A number of commercial neem pest control products and a laboratory prepared seed water extract were screened for antibacterial activity against bacteria with different Gram staining reactions, morphologies and pathogenicity using the agar diffusion technique. The neem component of the Trifolio-M GmbH commercial products, termed "active ingredient", and the unformulated product, MIDECOL-CF, exhibited antibacterial activity against Gram-positive and -negative bacteria including phytopathogens. The formulations of the Trifolio-M GmbH products were themselves shown to possess considerable antimicr

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3

Mohammadihashemi, Marjan. "Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/7411.

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The continuous emergence of drug-resistance pathogens is a global concern. As a result, substantial effort is being expended to develop new therapeutics and mechanisms for controlling microbial growth to avoid entering a "post-antibiotic" era in which commonly used antibiotics are no longer effective in treating infections. In this work, we investigate the efficacy and application of ceragenins as non-peptide mimics of antimicrobial peptides (AMPs). First, this work examines the susceptibility of drug-resistant Gram-negative bacteria. The susceptibility of colistin-resistant clinical isolates

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4

Dorman, Hugh Jude Damien. "Phytochemistry and bioactive properties of plant volatile oils : antibacterial, antifungal and antioxidant activities." Thesis, University of Strathclyde, 1999. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21318.

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Aromatic and medicinal plants have been recognized since antiquity as possessing biological activities; chief amongst these are their antibacterial, antifungal and antioxidant properties. In this study, the chemical composition, the antimicrobial and in vitro antioxidant bioactivities the volatile oils extracted by hydrodistillation from aromatic and medicinal members of the plant families Geraniaceae: geranium (Pelargonium graveolens L'Herit); Lamiaceae: melissa (Melissa officinalis L.), monarda (Monarda citriodora var. citriodora Cerv. ex Lag.), oregano (Origanum vulgare ssp. hirtum (Link) L

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5

Mogashoa, Motanti Mary. "Isolation and characterisation of antifungal and antibacterial compounds from Combretum molle (Combretaceae) leaf extracts." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/60270.

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The main aim of this study was to isolate and characterise antifungal and antibacterial compounds from leaf extracts of Combretum molle which belonging to the Combretaceae family. C. molle is one of the commonly used medicinal plants in southern Africa for numerous ailments. Three animal fungal pathogens, namely, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and five plant fungal pathogens, namely, Aspergillus niger, Aspergillus parasiticus, Fusarium oxysporum, Penicillium janthinellum, Rhizoctonia solani and four nosocomial bacteria Staphylococcus aureus, Enterococcus faec

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6

Singh, R. "Structure-function studies and evaluating the medical applications potential of two newly identified plant lectins." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2016. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/5879.

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7

Wang, Tao Verfasser], and Jeroen S. [Akademischer Betreuer] [Dickschat. "Discovery of antifungal and antibacterial volatile natural products and synthetic drug analogs / Tao Wang ; Betreuer: Jeroen S. Dickschat." Braunschweig : Technische Universität Braunschweig, 2018. http://d-nb.info/1175815454/34.

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8

Sousa, Zulane Lima. "Atividades biológicas de extratos e frações das folhas de Persea americana e Syzygium malaccense." Departamento de Biointeração, 2016. http://repositorio.ufba.br/ri/handle/ri/24116.

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Submitted by Renorbio (renorbioba@ufba.br) on 2017-08-15T14:32:14Z No. of bitstreams: 1 Tese_ Zulane Lima Sousa_ Atividades biológicas de extratos e frações das folhas de Persea americana e Syzygium malaccense_ 2016.pdf: 3239265 bytes, checksum: 5c62167b6ccb9fb8640e54efc7cd1af4 (MD5)<br>Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2017-08-28T13:56:26Z (GMT) No. of bitstreams: 1 Tese_ Zulane Lima Sousa_ Atividades biológicas de extratos e frações das folhas de Persea americana e Syzygium malaccense_ 2016.pdf: 3239265 bytes, checksum: 5c62167b6ccb9fb8640e54efc7cd1af4 (MD5)<

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9

Elashi, Balsam. "The antimicrobial and antifungal efficacy of indigenous plant extracts against streptococcus mutans, Escherichia colia and Candida albicans." University of the Western Cape, 2015. http://hdl.handle.net/11394/4246.

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Magister Scientiae Dentium - MSc(Dent)<br>The antimicrobial and antifungal efficacy of indigenous plant extracts against Streptococcus mutans , Escherichia coli and Candida albicans .Aim: To determine the antimicrobial and antifungal efficacy of indigenous plant extracts, Tamarindus Indica (T. ndica), Hibiscus sabdariffa (H. sabdaraffi), Adansonia digitata (A.digitata) and Moringa oleifera (M. oleifera) against Streptococcus mutans ( S. mutans ), Escherichia coli ( E. coli ) and Candida albicans (C. albicans) objectives:The objectives of this study were to: 1.Measure the zones of growt

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10

Alasmary, Fatmah A. S. "Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents. An investigation into the synthesis of substituted benzimidazoles and their evaluation in vitro for antimicrobial activity." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6325.

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Microbe resistence is a serious issue, especially as they have become resistant to most well known drugs. Therefore this is considered as a global problem and is now dealt with at a poitical level. Since no new classes of antimicrobial agents have been discovered in the past three deacdes, the development of new drugs is extremely urgent. Therefore the aim of this project was to synthesise derivatives of benzimidazole, and then assesses their antimicrobial activities in vitro by using disc (well) diffusion and MICs tests. A total of 69 benzimidazole derivatives, with substituents at pos

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11

Kelmelytė, Edita. "3-amino rodanino 3-, 5-, 3,5- pakeistų darinių sintezė ir jų antibakterinio bei priešgrybelinio aktyvumo įvertinimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2013. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2013~D_20130614_133357-43243.

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Darbo tikslas – sintetinti potencialius antibakterinius ir priešgrybelinius 3-amino rodanino darinius su pakaitais 3-oje ir 5-oje padėtyse bei ištirti jų struktūros įtaką aktyvumui. Tyrimo metodai – junginių antimikrobinio ir priešgrybelinio aktyvumo bei toksiškumo prognozė atlikta naudojant PASS programą. Antimikrobinis ir priešgrybelinis aktyvumas tirtas in vitro serijinio skiedimo standžioje terpėje metodu. Tyrimo rezultatai – PASS programa priešgrybelinį aktyvumą prognozavo visiems junginiams didesne tikimybe nei antibakteriniam. Pastarojo neprognozavo trims junginiams. Junginiams, kuriem

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Alasmary, Fatmah Ali Saeed. "Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents : an investigation into the synthesis of substituted benzimidazoles and their evaluation in vitro for antimicrobial activity." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6325.

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Microbe resistence is a serious issue, especially as they have become resistant to most well known drugs. Therefore this is considered as a global problem and is now dealt with at a poitical level. Since no new classes of antimicrobial agents have been discovered in the past three deacdes, the development of new drugs is extremely urgent. Therefore the aim of this project was to synthesise derivatives of benzimidazole, and then assesses their antimicrobial activities in vitro by using disc (well) diffusion and MICs tests. A total of 69 benzimidazole derivatives, with substituents at positions

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13

Pereira, Dayane Kelly Sabec. "Síntese, caracterização e avaliação da atividade antimicrobiana de complexos metálicos sintetizados com ligantes orgânicos." Universidade Federal de Goiás, 2015. http://repositorio.bc.ufg.br/tede/handle/tede/5436.

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Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2016-04-04T21:35:12Z No. of bitstreams: 2 Dissertação - Dayane Kelly Sabec Pereira - 2015.pdf: 7161660 bytes, checksum: 9e90c47a6af39120173e8142ccb64d21 (MD5) license_rdf: 19874 bytes, checksum: 38cb62ef53e6f513db2fb7e337df6485 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-04-05T11:15:37Z (GMT) No. of bitstreams: 2 Dissertação - Dayane Kelly Sabec Pereira - 2015.pdf: 7161660 bytes, checksum: 9e90c47a6af39120173e8142ccb64d21 (MD5) license_rdf: 19874 bytes, checksum: 38cb62ef53e6f513db2fb7e337df

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14

Cheung, Yin-mei. "Evaluation of a multiplex polymerase chain reaction assay for detection of silent fluoroquinolone-resistant determining mutations in streptococcus pneumoniae." Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31970941.

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15

Ževžikovienė, Augusta. "Naujų 4-tiazolidinonų, turinčių sulfanilamido, alilamino ir nitrofurano farmakoforus, priešmikrobinių savybių tyrimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120918_161940-39143.

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Klinikinėje praktikoje infekcinėms ligoms gydyti vartojama daugiau kaip 200 priešmikrobinių medžiagų, tačiau infekcinės ligos yra viena dažniausių mirties priežasčių ir naujų priešmikrobinių vaistų poreikis nemažėja. Modifikuojant 4-tiazolidinono žiedą susintetinami įvairaus biologinio aktyvumo junginiai. 4-tiazolidinono dariniai su sulfanilamido farmakoforu yra aktyvesni už sulfanilamidus prieš bakterijas ir pasižymi priešgrybeliniu poveikiu; su nitrofurano farmakoforu yra vieni aktyviausių priešmikrobinių junginių. Alilaminą įjungus į molekulę kartu su jau anksčiau žinomais farmakoforais, ti

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16

Montes, Ricardo Carneiro. "Amidas halogenadas: reações de acoplamento e investigação in silico da atividade antimicrobiana." Universidade Federal da Paraíba, 2016. http://tede.biblioteca.ufpb.br:8080/handle/tede/8806.

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Submitted by Cristhiane Guerra (cristhiane.guerra@gmail.com) on 2017-02-01T12:59:21Z No. of bitstreams: 1 arquivotototal.pdf: 10138565 bytes, checksum: 12bbe7fe2ab950106307c9ed9db462d2 (MD5)<br>Made available in DSpace on 2017-02-01T12:59:21Z (GMT). No. of bitstreams: 1 arquivotototal.pdf: 10138565 bytes, checksum: 12bbe7fe2ab950106307c9ed9db462d2 (MD5) Previous issue date: 2016-08-12<br>This study aimed to prepare a collection of benzylamides to-halogenated derivatives of structurally related benzoic and cinnamic acids by coupling reactions with 4- (chlorine, bromine and fluro) benzylamines

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Araújo, Marianna Oliveira de. "Preparação de derivados do ácido caféico e avaliação das suas atividades antimicrobianas." Universidade Federal da Paraíba, 2017. http://tede.biblioteca.ufpb.br:8080/handle/tede/9074.

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Submitted by Maike Costa (maiksebas@gmail.com) on 2017-07-07T14:16:10Z No. of bitstreams: 1 arquivototal.pdf: 5188548 bytes, checksum: 01435a9a75b591e5478f88f4cc0f7434 (MD5)<br>Made available in DSpace on 2017-07-07T14:16:10Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 5188548 bytes, checksum: 01435a9a75b591e5478f88f4cc0f7434 (MD5) Previous issue date: 2017-02-23<br>The present dissertation show the results obtained from the study of a collection of structurally related caffeic acid derived and their antimicrobial evaluation. Increased microbial resistance to drugs, causing thousands o

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18

Cheung, Yin-mei, and 張燕湄. "Evaluation of a multiplex polymerase chain reaction assay for detection of silent fluoroquinolone-resistant determining mutations instreptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31970941.

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Giordani, Claudia. "Atividade antimicrobiana de extratos vegetais e toxicidade em modelos alternativos." Universidade Federal de Pelotas, 2017. http://guaiaca.ufpel.edu.br:8080/handle/prefix/3957.

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Submitted by Ubirajara Cruz (ubirajara.cruz@gmail.com) on 2018-06-04T17:41:52Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) tese_claudia_giordani.pdf: 2611038 bytes, checksum: 63cd2ddef997869f917a5acd07802d6d (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2018-06-05T11:53:32Z (GMT) No. of bitstreams: 2 tese_claudia_giordani.pdf: 2611038 bytes, checksum: 63cd2ddef997869f917a5acd07802d6d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Made available in DSpace on 2018-06-05T11:53

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Medu, Erere Ohwofasa. "Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B." Thesis, Robert Gordon University, 2013. http://hdl.handle.net/10059/832.

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In view of the increasing global challenge of bacterial resistance, there exists an urgent need for the rationale development of antibacterial compounds with either novel or multiple mechanisms of action. Two chalcone-derivatives, F1 and F23, demonstrated MICs within the range of 16 to >512 μg/ml against two plant pathogens (P. caratovoram and C. michiganensis subsp. michiganensis) as well as important clinical bacterial species. Both compounds displayed an MIC of 32 μg/ml against quinolone-resistant S. aureus. Whilst possessing weak activities individually, each semi-synthetic agent displayed

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21

Yasrebi, Kaveh [Verfasser], Andreas [Gutachter] Hilgeroth, Sibel Gutachter] Süzen, and Michael [Gutachter] [Lalk. "Synthesis and biological evaluation of trisindolyl-cycloalkanes and bis-indolyl naphthalene small molecules as potent antibacterial and antifungal agents / Kaveh Yasrebi ; Gutachter: Andreas Hilgeroth, Sibel Süzen, Michael Lalk." Halle (Saale) : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2020. http://d-nb.info/1237685796/34.

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22

Veale, Clinton Gareth Lancaster. "Synthetic analogues of marine bisindole alkaloids as potent selective inhibitors of MRSA pyruvate kinase." Thesis, Rhodes University, 2014. http://hdl.handle.net/10962/d1020893.

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Globally, methicillin resistant Staphylococcus aureus (MRSA) has become increasingly difficult to manage in the clinic and new antibiotics are required. The structure activity relationship (SAR) study presented in this thesis forms part of an international collaborative effort to identify potent and selective inhibitors of an MRSA pyruvate kinase (PK) enzyme target. In earlier work the known marine natural product bromodeoxytopsentin (1.6), isolated from a South African marine sponge Topsentia pachastrelloides, exhibited selective and significant inhibition of MRSA PK (IC₅₀ 60 nM). Accordingly

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23

Rossato, Luana. "INTERAÇÕES DE AGENTES ANTIFÚNGICOS E ANTIBACTERIANOS FRENTE A Cryptococcus neoformans ANTES E APÓS INDUÇÃO CAPSULAR." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/5971.

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Fundação de Amparo a Pesquisa do Estado de São Paulo<br>The genus Cryptococcus consists of encapsulated yeasts that cause mainly cryptococcal meningoencephalitis in immunocompromised patients. This mycosis shows high percentage of morbidity and mortality. The fault is not the recommended therapeutic conveniently clarified and, concerning the susceptibility of the fungus to the antifungal, resistance detected in vitro is less frequent than the therapeutic failures. At this juncture, we discuss two aspects: a) considered the presence of the capsule in susceptibility testing, and b) evaluated com

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Oliveira, Karen Kelly Carvalho de. "Atividade antimicrobiana de basidiomicetos ocorrentes na Amazônia." Universidade Federal do Amazonas, 2014. http://tede.ufam.edu.br/handle/tede/4285.

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Submitted by Alisson Mota (alisson.davidbeckam@gmail.com) on 2015-07-07T18:57:29Z No. of bitstreams: 1 Dissertação - Karen Kelly Carvalho de Oliveira.pdf: 2064619 bytes, checksum: 99e96187d8cd6db44d7bb15b47d1bbe8 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2015-07-07T19:07:54Z (GMT) No. of bitstreams: 1 Dissertação - Karen Kelly Carvalho de Oliveira.pdf: 2064619 bytes, checksum: 99e96187d8cd6db44d7bb15b47d1bbe8 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2015-

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Cai, Yanling. "Titanium Dioxide Photocatalysis in Biomaterials Applications." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160634.

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Despite extensive preventative efforts, the problem of controlling infections associated with biomedical materials persists. Bacteria tend to colonize on biocompatible materials and form biofilms; thus, novel biomaterials with antibacterial properties are of great interest. In this thesis, titanium dioxide (TiO2)-associated photocatalysis under ultraviolet (UV) irradiation was investigated as a strategy for developing bioactivity and antibacterial properties on biomaterials. Although much of the work was specifically directed towards dental materials, the results presented are applicable to a

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Rojas, Maria J. "Study of Plants Used Against Infections by California Native American Tribes." DigitalCommons@CalPoly, 2020. https://digitalcommons.calpoly.edu/theses/2248.

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The objectives of this research were to evaluate the antibacterial activity and to determine the chemical composition of a list of medicinal plants used by Native Americans in California. Artemisia californica, Mimulus aurantiacus, Equisetum telmateia, Equisetum hyemale, and Marah fabacea were selected from a list of plants reported as having been used for ailments related to infections by tribes located in California. The extracts obtained through steam distillation from E. telmateia, E. hyemale and M. fabacea were assayed for in vitro antibacterial activity against 16 Gram-negative and 6 Gra

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Silva, Fernanda Dias da. "Mecanismo de ação da microplusina, um peptídeo quelante de cobre com atividade antimicrobiana." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-02122008-180144/.

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Peptídeos antimicrobianos (PAMs) fazem parte de um dos mecanismos da imunidade inata contra infecções. A microplusina é um PAM de 10.204 Da, isolado da hemolinfa livre de células e dos ovos do carrapato Rhipicephalus (Boophilus) microplus. É um PAM aniônico em pH fisiológico, possui seis resíduos de cisteína, com formação de três pontes dissulfeto, além de sete resíduos de histidina concentrados principalmente na sua porção C-terminal. O presente trabalho teve como objetivo investigar o mecanismo de ação antimicrobiana da microplusina. A microplusina recombinante é ativa contra várias bactéria

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Carneiro, Ana Lúcia Basílio. "Potencial citotóxico e antimicrobiano de plantas da reserva florestal Adolpho Ducke, Manaus-AM." Universidade Federal do Amazonas, 2015. http://tede.ufam.edu.br/handle/tede/4388.

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Mathekga, Abbey Danny Matome. "Antimicrobial activity of Helichrysum species and the isolation of a new phloroglucinol from Helichrysum caespititium." Diss., Pretoria : [s.n.], 2001. http://upetd.up.ac.za/thesis/available/etd-04012003-141811.

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Pereira, Júnior Raimundo Carlos, and 92-99160-4279. "Caracterização química e avaliação dos potenciais antimicrobiano, inseticida e citotóxico de óleos essenciais obtidos de Myrcia spp. (myrtaceae) ocorrentes em ecossistema de terra firme (Amazônia)." Universidade Federal do Amazonas, 2018. https://tede.ufam.edu.br/handle/tede/6718.

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Camargo, Marlene Rodrigues Marcelino. "Avaliação da atividade antimalárica e antimicrobiana de geissosperum argenteum Woodson e Minguartia guianensis Aubl coletadas em Roraima." Universidade Federal de Roraima, 2011. http://www.bdtd.ufrr.br/tde_busca/arquivo.php?codArquivo=130.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Dentre as espécies florestais nativas da Amazônia utilizadas por populações tradicionais na terapêutica de diversos problemas de saúde estão a Geissospermum argenteum Woodson, uma Apocynaceae, e a Minquartia guianensis Aubl., da família Olacaceae. Entre os problemas de saúde está a malária, que no Brasil e no mundo ainda é um grave problema de saúde pública. Outro agravo à saúde de importância são infecções microbianas, pois os micro-organismos têm desenvolvido resistência aos agentes antimicrobianos. Neste trabalho, foram coletada

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ANGRI, MATTEO. "FOOD SAFETY AND QUALITY IN DEVELOPING COUNTRIES: THE ROLE OF LACTIC ACID BACTERIA." Doctoral thesis, Università Cattolica del Sacro Cuore, 2016. http://hdl.handle.net/10280/10797.

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La sicurezza e la qualità degli alimenti sono tutt’ora un problema critico per i paesi in via di sviluppo. Le diete a basso contenuto di acido folico, per esempio, possono causare gravi problemi di salute, soprattutto nei bambini. Gravi disturbi legati al tubo neurale (DTN) nei neonati possono derivare infatti da madri che hanno insufficiente apporto di acido folico (400-600 g / giorno) durante il periodo di gravidanza. Inoltre, se non adeguatamente protetti o trattati, I prodotti alimentari possono essere vettori di funghi e batteri patogeni rappresentando una fonte potenziale di malattie per

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ANGRI, MATTEO. "FOOD SAFETY AND QUALITY IN DEVELOPING COUNTRIES: THE ROLE OF LACTIC ACID BACTERIA." Doctoral thesis, Università Cattolica del Sacro Cuore, 2016. http://hdl.handle.net/10280/10797.

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La sicurezza e la qualità degli alimenti sono tutt’ora un problema critico per i paesi in via di sviluppo. Le diete a basso contenuto di acido folico, per esempio, possono causare gravi problemi di salute, soprattutto nei bambini. Gravi disturbi legati al tubo neurale (DTN) nei neonati possono derivare infatti da madri che hanno insufficiente apporto di acido folico (400-600 g / giorno) durante il periodo di gravidanza. Inoltre, se non adeguatamente protetti o trattati, I prodotti alimentari possono essere vettori di funghi e batteri patogeni rappresentando una fonte potenziale di malattie per

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34

Peter, Cristina Mendes. "Atividade antimicrobiana de extratos hidroalcoólicos de própolis marrom, verde e de abelhas jataí (Tetragonisca angustula) frente a micro-organismos infecciosos de interesse em Medicina Veterinária e Humana." Universidade Federal de Pelotas, 2015. http://repositorio.ufpel.edu.br:8080/handle/prefix/3379.

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Submitted by Ubirajara Cruz (ubirajara.cruz@gmail.com) on 2017-05-08T14:44:48Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_Cristina_Peter.pdf: 1012287 bytes, checksum: a6b5ae3184db955c29ee2d8a7adfa70f (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-05-08T14:56:02Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_Cristina_Peter.pdf: 1012287 bytes, checksum: a6b5ae3184db955c29ee2d8a7adfa70f (MD5)<br>Made available in DSpace on 2017-0

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Kfoury, Miriana. "Préparation, caractérisation physicochimique et évaluation des propriétés biologiques de complexes d'inclusion à base de cyclodextrines : applications à des principes actifs de type phénylpropanoïdes." Thesis, Littoral, 2015. http://www.theses.fr/2015DUNK0397/document.

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Les phénylpropanoïdes (PPs) constituent l'une des familles les plus abondantes des métabolites secondaires dans le règne végétal. Ils protègent les plantes contre les stress biotiques et abiotiques. De nos jours, les études portent sur l'utilisation des PPs comme alternatifs aux agents antimicrobiens, antioxydants et anti-inflammatoires de synthèse pour leur incorporation dans la formulation des produits alimentaires et pharmaceutiques. Cependant, l'utilisation de PPs est généralement limitée en raison de leur faible solubilité, stabilité et volatilité. L'objectif de notre travail a été d'enca

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Alfindee, Madher N. "Synthesis and Biological Studies of Amphiphilic Compounds Derived from Saccharides and Aminoglycosides." DigitalCommons@USU, 2019. https://digitalcommons.usu.edu/etd/7568.

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Adjacent cells communicate through gap junctions (GJs). These GJs are formed by head to head docking of two hemichannels (HCs) from two adjacent cells. HCs are connexin hexamer proteins. Connexin mutation is the most frequent cause of childhood hearing loss. This hearing impairment affects 2 in every 2000 children. Inhibition of the HCs might be the key factor to treat such disorders. A library of amphiphilic kanamycins was synthesized to be tested as HC inhibitors. These compounds showed excellent inhibition activity in comparison with the parent compound (kanamycin A) with less toxicity. A l

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Costa, Helen Paula Silva da. "PurificaÃÃo e caracterizaÃÃo de um inibidor de tripsina com atividade antimicrobiana da torta de pinhÃo-manso (Jatropha curcas L.)." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7773.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>O resÃduo (torta) obtido apÃs a extraÃÃo de Ãleo das sementes de pinhÃo-manso (Jatropha curcas) para a produÃÃo de biodiesel Ã tÃxico. Apesar dos entraves relacionados Ã sua utilizaÃÃo na alimentaÃÃo animal, existem evidÃncias de que esse resÃduo tem grande potencial de utilizaÃÃo biotecnolÃgica graÃas ao arsenal de molÃculas que o constitui. Assim, o presente trabalho teve como foco a purificaÃÃo e caracterizaÃÃo de um inibidor de tripsina da torta de pinhÃo-manso, v

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Esteves, Ana Teresa Martins. "Plantas endémicas portuguesas com utilização medicinal." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5307.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>Os primeiros medicamentos que surgiram tinham como base os conhecimentos etnobotânicos das populações, ou seja, as populações conheciam as plantas locais e as suas aplicações para o tratamento e prevenção das patologias. Com o presente trabalho procura-se descrever os princípios ativos presentes nas plantas e descrever a aplicação medicinal de plantas endémicas portuguesas. No desenvolvimento do trabalho verificou-se que em

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Bonifácio, Bruna Vidal. "Prospecção químico-biológica de extratos hidroetanólicos das folhas de Astronium urundeuva na investigação do potencial antifúngico /." Araraquara, 2018. http://hdl.handle.net/11449/182249.

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Orientador: Taís Maria Bauab<br>Resumo: Apesar do grande avanço tecnológico direcionado à indústria farmacêutica, os micro-organismos continuam adquirindo cada vez mais resistência aos fármacos convencionalmente utilizados e, pesquisadores de diversas áreas buscam novas fontes antimicrobianas de origem natural, a exemplo das plantas medicinais. Dentre as infecções fúngicas, destacam-se aquelas causadas por leveduras do gênero Candida sp. a exemplo da a candidíase vulvovaginal (CVV). A planta Astronium urundeuva (Allemao) Engl. apresenta uma série de propriedades biológicas, incluindo a ativida

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Joaquim, Angélica Rocha. "Síntese de derivados de 8-hidroxiquinolina e avaliação da atividade antimicrobiana." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/181465.

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A prospecção e síntese de novos derivados de 8-hidroxiquinolina está em ascensão devido às suas diversas atividades biológicas. Neste trabalho é relatada a síntese e avaliação da atividade antimicrobiana de novos derivados contendo uma sulfonamida substituída na posição 5 da 8-hidroxiquinolina ou um grupamento aminossubstituído na posição 7 da 5-cloro-8-hidroxiquinolina ou 5-cloro-8-metoxiquinolina. Os derivados 5-sulfonamidas foram preparados por clorossulfonação seguida da reação com a amina apropriada. Os derivados 7-aminossubstituído foram sintetizados através da metilação da hidroxila da

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Ribeiro, Martins Xavier Nuno Manuel. "Synthesis of new sugar derivatives containing an α,β -unsaturated carbonyl system in their structure and biological evaluation". Thesis, Lyon, INSA, 2011. http://www.theses.fr/2011ISAL0023.

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Ce travail de doctorat porte sur la synthèse et utilisation de bicyclolactones glycidiques, de façon à accéder des dérivés de sucres contenant un système carbonylé α,β-insaturé. Trois types de bicyclolactones ont été étudiés: butenolides liés à des cycles furanose, butenolides fusionnés à des cycles pyranose, comprenant S- et NH-analogues et carboxyméthyle glycosides lactones (CMGLs). La méthodologie de synthèse de butenolides sur motif sucre est basée sur l’oléfination de Wittig de 3 ou 5-cétosucres et lactonisation intramoléculaire spontanée de gamma-hydroxyesters α,β-insaturés intermédiaire

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CUNHA, Marcelo Holanda da. "Composição química e atividade biológica do extrato hidroalcoolico de própolis preta." Universidade Federal de Campina Grande, 2018. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/880.

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Submitted by Deyse Queiroz (deysequeirozz@hotmail.com) on 2018-06-05T13:11:17Z No. of bitstreams: 1 MARCELO HOLANDA DA CUNHA - DISSERTAÇÃO PPGSA PROFISSIONAL 2018..pdf: 1249369 bytes, checksum: 6fd10dae8346a148f59677b96d3a3f5a (MD5)<br>Made available in DSpace on 2018-06-05T13:11:17Z (GMT). No. of bitstreams: 1 MARCELO HOLANDA DA CUNHA - DISSERTAÇÃO PPGSA PROFISSIONAL 2018..pdf: 1249369 bytes, checksum: 6fd10dae8346a148f59677b96d3a3f5a (MD5) Previous issue date: 2018-03-05<br>Neste trabalho buscou-se investigar a composição química, o efeito antifúngico e antibacteriano do extrato da própoli

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43

Cunha, Let?cia Figueiredo. "Plantas do cerrado brasileiro: triagem fitoqu?mica e de atividades biol?gicas de esp?cies nativas do munic?pio de Diamantina, regi?o do Vale do Jequitinhonha, Minas Gerais." UFVJM, 2016. http://acervo.ufvjm.edu.br/jspui/handle/1/1433.

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?rea de concentra??o: Ci?ncias farmac?uticas.<br>Data de aprova??o ausente.<br>Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2017-08-01T18:51:24Z No. of bitstreams: 2 leticia_figueiredo_cunha.pdf: 6440587 bytes, checksum: 74ac0e7008e3cbee954ff6c0815803c4 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2017-08-14T16:34:13Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) leticia_figueiredo_cunha.pdf: 64405

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Meyo, Degboevi Henri. "Variabilité intra spécifique de la composition chimique des connexes issus de la première transformation du bois de différentes essences gabonaises et valorisations chimiques potentielles." Electronic Thesis or Diss., Université de Lorraine, 2020. http://www.theses.fr/2020LORR0203.

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Au cours de ce travail, le taux d’extraits d’écorce, duramen et aubier de quatre essences gabonaises a été évalué par la technique d’extraction accélérée ASE 200 et au Soxhlet pour les extractions successives au dichlorométhane, acétone, toluène/éthanol et eau. Egalement, des extractions en parallèle à l’éthanol, eau/éthanol et eau dont les extraits ont permis de réaliser la suite des travaux avec le taux d’extraits variant de 05 à 26 %. Les phénols totaux contenus dans les extractibles ont été évalués par la méthode de Folin–Ciocalteu en utilisant l’acide gallique comme standard. La teneur va

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45

GRENGA, LUCIA. "Study of the biological role of the protein-protein interaction in the divisome assembling and functionality." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/202281.

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L’incremento delle infezioni causate da batteri resistenti alle attuali terapie e la scarsità di farmaci efficaci per il loro trattamento spingono la comunità scientifica a cercare strategie innovative, per identificare nuove classi di farmaci antibatterici. Un modo per raggiungere questo obiettivo è quello di sviluppare farmaci che hanno nuovi meccanismi d’azione. Diverse caratteristiche delle proteine dell’apparato di divisione (o divisoma) batterico suggeriscono che esse potrebbero essere dei bersagli ideali per nuovi antimicrobici. Poiché la divisione cellulare richiede molteplici interaz

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46

Dorla, Emmanuelle. "Étude phytochimique et propriétés bioactives de Peperomia borbonensis (Miq.) Piperaceae." Thesis, La Réunion, 2016. http://www.theses.fr/2016LARE0027.

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Les maladies impliquant des micro-organismes représentent un problème majeur de santé publique en raison du fort taux de mortalité provoqué par l'accroissement et l'émergence de souches résistantes. De même, les régions tropicales du Monde et La Réunion doivent faire face depuis plusieurs années à la pression accrue d'arthropodes ravageurs de cultures et vecteurs de maladies. Pour lutter contre ces arthropodes, les pesticides synthétiques aux conséquences désastreuses sur l'Homme et l'environnement sont principalement utilisés. Depuis quelques années, on observe un phénomène grandissant de rés

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47

Yagi, Sakina. "Etudes phytochimique et biologique de plantes soudanaises : Hydnora johannis Beccari (Hydnoraceae) et Citrullus lanatus (Thunb.) Matsum. et Nakai var. citroides (Bailey) Mansf. (Cucurbitaceae)." Thesis, Nancy 1, 2011. http://www.theses.fr/2011NAN10138.

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Différents extraits ont été préparés à partir de racines de H. johannis et différents tests biologiques ont été appliqués en vue de rechercher différentes activités. L'extrait aqueux s'est montré particulièrement actif sur Enterococcus fecalis, Staphylococcus aureus et Bacillus. Les extraits aqueux dépourvus de tanins et les tanins isolés ne présentent pas d'activité antibactérienne. L'effet synergétique des composés serait donc responsable de l'activité antibactérienne de la plante. Une activité antifongique sur Microsporum canis, une propriété antiradicalaire et une activité antiglycation on

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Martins, Táric Ramon Marques. "Síntese, caracterização e avaliação da atividade biológica de ligantes orgânicos da classe das tiossemicarbazonas, semicarbazonas e hidrazonas." Universidade Federal de Goiás, 2017. http://repositorio.bc.ufg.br/tede/handle/tede/7762.

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Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-09-12T17:30:52Z No. of bitstreams: 2 Dissertação - Táric Ramon Marques Martins - 2017.pdf: 2380133 bytes, checksum: 33d24de03c73f9a88934ebdeafa14222 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-09-19T13:43:32Z (GMT) No. of bitstreams: 2 Dissertação - Táric Ramon Marques Martins - 2017.pdf: 2380133 bytes, checksum: 33d24de03c73f9a88934ebdeafa14222 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998e

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Costa, Helen Paula Silva da. "Purificação e caracterização de um inibidor de tripsina com atividade antimicrobiana da torta de pinhão-manso (Jatropha curcas L.)." reponame:Repositório Institucional da UFC, 2012. http://www.repositorio.ufc.br/handle/riufc/16947.

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COSTA, Helen Paula Silva da. Purificação e caracterização de um inibidor de tripsina com atividade antimicrobiana da torta de pinhão-manso (Jatropha curcas L.). 118 f. : Dissertação (Mestrado) - Universidade Federal do Ceará, Centro de Ciências, Departamento de Bioquímica e Biologia Molecular, Programa de Pós-Graduação em Bioquímica. Fortaleza-CE, 2012.<br>Submitted by Eric Santiago (erichhcl@gmail.com) on 2016-05-20T13:42:27Z No. of bitstreams: 1 2012_dis_hpscosta.pdf: 3018720 bytes, checksum: eb4b6b465befb3e7211b53415f21b787 (MD5)<br>Approved for entry into archive by demia Maia (demiamlm@gm

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Nate, Zondi. "Green synthesis of copper and silver nanoparticles and their antimicrobial activity." Thesis, Vaal University of Technology, 2018. http://hdl.handle.net/10352/424.

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M. Tech. (Department of Chemistry, Faculty of Applied and Computer Sciences), Vaal University of Technology<br>The present study includes the use of a green synthetic method to prepare copper and silver nanoparticles using chitosan, aqueous extracts of Camellia sinensis, Combretum molle and Melia azedarach linn leaves. This study aims to investigate the influence of capping and precursor concentration on the properties of silver nanoparticles with emphasis on the medicinal plants chosen. The effect of capping agent on the properties of copper nanoparticles is also investigated. The phytochemic

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