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1

Vyas, Kamal Kant, Sangeeta Rajpurohit, and Yudhishthir Vaishnav. "Synthesis and Characterization of Benzimidazole Derivatives and Evaluation of Antimicrobial activity." Oriental Journal Of Chemistry 39, no. 4 (2023): 996–1001. http://dx.doi.org/10.13005/ojc/390424.

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A series of benzimidazole derivatives were synthesized for this investigation. NMR and IR spectrum analysis as well as carbon, hydrogen, and nitrogen studies were used to characterize these novel synthesized derivatives. Antibacterial and antifungal tests were conducted on all of the newly synthesized compounds. Ciprofloxacin and fluconazole were utilized as reference medications in antibacterial and antifungal research, respectively. The microbiological assay revealed that the compounds show promising antibacterial and antifungal activity.
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2

M, Shoaib. "Synthesis, Antibacterial and Antifungal Properties of Cyclohexane Tosyloxyimine Derivative." Open Access Journal of Microbiology & Biotechnology 4, no. 3 (2019): 1–4. http://dx.doi.org/10.23880/oajmb-16000150.

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Due to increasing antimicrobial resistance, functionally substituted cyclohexane derivatives are being explored as potential antimicrobial agents. Reaction of diethyl 4 - hydroxy - 6 - (hyd - roxyimino) - 4 - methyl - 2 - phenylcyclohexane - 1,3 - dicarboxylate with 4 - toluene sulfonyl chloride in boiling acetone in the presence of equimolar triethylamine resulted in formation of diethyl - 4 - hydroxy - 4 - methyl - 2 - phenyl - 6 - ((tosyloxy)imino) cyclohexane - 1,3 - dicarboxylate. The structure of novel compound was characterized by 1 H and 13 C NMR spectra and elemental analysis was perf
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Mishra, Anshu, Ravi Kant Kushwaha, Akash Singh, Renu Khare, Sunil Kumar Verma, and Devendra Singh. "Unraveling the antifungal, antibacterial activity, and cytotoxicity analysis of Ziziphus oenoplia." Ecology, Environment and Conservation 31, Suppl (2025): S335—S338. https://doi.org/10.53550/eec.2025.v31i01s.057.

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Modern biomedical sciences are developing research in the field of antibacterial medications. The Indian traditional medical system of Ayurveda is being studied by researchers who are working to create new medications from natural resources. The majority of these medications have plant origins. This study studied the antifungal and antibacterial activity, along with the cytotoxicity of Ziziphus oenoplia. The fined powder of Ziziphus oenoplia was used, and a well diffusion assay was used to assess the antifungal and antibacterial activity. Finally, the cytotoxicity of the plant extract was also
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4

Niass, Ousmane, Issa Samb, Betemondji Desire Diatta, et al. "Phytochemical Screening, Secondary Metabolites Assay, Antioxidant, Antibacterial and Antifungal Activity of Clove Buds (Syzygiumaromaticum) Extracts." International Journal of Science and Research (IJSR) 12, no. 10 (2023): 1900–1905. http://dx.doi.org/10.21275/20011903.

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Lima, Luciana Alves Rodrigues dos Santos, Susana Johann, Patrícia Silva Cisalpino, Lúcia Pinheiro Santos Pimenta, and Maria Amélia Diamantino Boaventura. "In vitro antifungal activity of fatty acid methyl esters of the seeds of Annona cornifolia A.St.-Hil. (Annonaceae) against pathogenic fungus Paracoccidioides brasiliensis." Revista da Sociedade Brasileira de Medicina Tropical 44, no. 6 (2011): 777–80. http://dx.doi.org/10.1590/s0037-86822011000600024.

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INTRODUCTION: Fatty acids are abundant in vegetable oils. They are known to have antibacterial and antifungal properties. METHODS: Antifungal susceptibility was evaluated by broth microdilution assay following CLSI (formerly the NCCLS) guidelines against 16 fungal strains of clinical interest. RESULTS: In this work, fatty acid methyl esters (FAME) was able to inhibit 12 clinical strains of the pathogenic fungus Paracoccidioides brasiliensis and were also active in the bioautographic assay against Cladosporium sphaerospermum. CONCLUSIONS: FAME was a more potent antifungal than trimethoprim-sulf
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Saha, Repon Kumer, Srijan Acharya, Maha Jamiruddin, Priyanka Roy, Md Sohidul Islam, and Syed Sahidul Haque Shovon. "Antimicrobial effects of a crude plant lectin isolated from the stem of Tinospora tomentosa." Journal of Phytopharmacology 3, no. 1 (2014): 44–51. http://dx.doi.org/10.31254/phyto.2014.3107.

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Crude plant lectins were isolated from the stem of Tinospora tomentosa and found its antibacterial and antifungal effects. Lectins were isolated by ammonium sulphate precipitation method. Presence of carbohydrate and proteins were investigated by thin layer chromatography and infrared spectroscopy techniques. Lectin was characterized by its binding affinity with carbohydrates and human erythrocytes by hemagglutination inhibition assay and SDS-page gel electrophoresis. The amount of proteins was quantitatively measured by Lowry method. Antibacterial and antifungal activities were investigated b
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Kader, Md Abdul, Shumaia Parvin, Md Aktar Uzzaman Chowduri, and Md Ekramul Haque. "Antibacterial, antifungal and insecticidal activities of Ruellia tuberosa (L.) root extract." Journal of Bio-Science 20 (January 18, 2014): 91–97. http://dx.doi.org/10.3329/jbs.v20i0.17720.

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Context: Plants as therapeutics are popularized for thousands of years and people continue to rely on them for health care until now due to their effectiveness, easy availability, low cost and comparatively being devoid of serious toxic effects. Microorganisms such as bacteria, fungi and insects are developing resistance to the current therapies very easily and the currently available antibacterial, antifungal agents and pesticides are very much costly and toxic. So the current shift to the use of herbal antibacterial, antifungal agents and pesticides may be more effective, economic and advant
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8

Sabri, Gulnaaz, and Vimala Y. "ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF LEUCAS ASPERA FLOWERS FROM BIHAR, INDIA." Asian Journal of Pharmaceutical and Clinical Research 11, no. 2 (2018): 223. http://dx.doi.org/10.22159/ajpcr.2018.v11i2.21976.

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Objective: The aim of this study was to explicate antibacterial, antifungal, and antioxidant activities of Leucas aspera flowers.Methods: Antibacterial activity was done by agar diffusion method. The ethyl acetate extract of L. aspera flower was evaluated against both Gram-positive and Gram-negative bacteria. Antifungal activity was also done by agar diffusion method. The agar used for antifungal activity was Czapek Dox Agar. Nitric oxide scavenging assay and free radical scavenging assay were used for the antioxidant activity. Griess reagent was used in nitric oxide scavenging assay. 1,1-diph
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9

Dar, Umair Ikram, Farooq Saleem, and Saad Touqeer. "Antimicrobial and antioxidant activity of Embelia robusta: a common adulterant in black pepper." Pakistan Journal of Pharmaceutical Research 2, no. 2 (2016): 136. http://dx.doi.org/10.22200/pjpr.20162136-141.

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The present study was aimed to investigate the phytochemistry as well as the antibacterial, antifungal, antioxidant and irritant activities of fruit of Embelia robusta. Agar-well diffusion method was used for antimicrobial study whereas for antioxidant activity three tests namely, DPPH assay, β-Carotene assay and ascorbic acid content were performed. The results from antibacterial assay showed presence of antibacterial activity in all the three plant extracts (methanol, chloroform and n-hexane). Significant antioxidant activity was also found to be present and plant extracts showed no irritant
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10

Oke, D. Gbenga, and O. Oluyemi Oluranti. "Antifungal, Antibacterial and Phytochemical Properties of Petiveria Alliacea Plant from Iwo, Nigeria." Chemistry Research Journal 4, no. 1 (2019): 12–18. https://doi.org/10.5281/zenodo.13742371.

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<em>Petiveria</em> alliacea plant has been a medicinal plant for decades and has been used both in the traditional and modern ways over these periods. This article highlights part of its medicinal properties particularly, antimicrobial and phytochemicals. Antibacterial and antifungal assay was carried out on both the leaves and root extracts and it was discovered that, for the antibacterial, the methanolic extracts of roots are more effective while the chloroform extracts of leaves are more efficacious. The leaves extracts however proved to be a better antifungal than the root extracts. The fo
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D.K., Ramesh, Gopala Krishna B, Mruthyunjaya J. H., Manjunatha S. Katagi, and Girish Bolakatti. "Synthesis and Antimicrobial Evaluation of Newly Sythesized Triazolothiadiazole Analogs." International Journal of Drug Design and Discovery 4, no. 2 (2025): 1050–55. https://doi.org/10.37285/ijddd.4.2.3.

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Potassium dithiocarbazinate of isonicotinic acid hydrazide 1a was treated with hydrazine hydrate to yield 1,2,4-triazole 1b which up on treatment with various carboxylic acids to get series of novel 6-(substituted)-3-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b]thiadiazole (TT1-TT11) The title compounds were characterized on the basis of IR, 1H NMR, 13C NMR and Mass spectral (MS) studies. Further they were evaluated for antibacterial and antifungal by Agar diffusion assay method, antitubercular activity by Micro-plate Alamar Blue Assay (MABA). Among eleven synthesized novel compounds TT2, TT3, TT10, a
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RehmanOng, Rubina, Muhammad Shahzad Aslam, Bashir Ahmad Choudhary, Muhammad Uzair, Abdul Subhan Ijaz, and Muhammad Syarhabil Ahmad. "Biological Screening of Eichornia crassipes against Different Pathogenic Microbes: An In Vitro Study." Recent Advances in Biology and Medicine 02 (2016): 79. http://dx.doi.org/10.18639/rabm.2016.02.336646.

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The present research is a biological screening ofEichornia crassipes(Pontederiaceae). Dichloromethane and methanol extracts of the whole plant were investigated for their antibacterial, antifungal, phytotoxic, and cytotoxic activities. The antibacterial activity was evaluated using agar well-diffusion method againstBacillus subtilis, Staphylococcus aureus, Escherichia coli, Shigella flexneri, Pseudomonas aeruginosa,andSalmonellatyphi. The antifungal activity was evaluated using the agar tube–dilution method againstCandida albicans,Candida glabrata,Aspergillus flavus,Microsporum canis,andFusari
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13

Abid, Sulayman. "ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF BREYNIA DISTICHA AND VERNONIA ELAEAGNIFOLIA." Journal of Applied Pharmacy 7 (2015): 152. http://dx.doi.org/10.21065/19204159.7.152.

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The present study was aimed to investigate the phytochemistry and to determine the antibacterial, antifungal and antioxidant activities of the methanolic extract of the two plants namely, Breyniadistichaand Vernoniaelaeagnifolia. Antimicrobial activity was determined using disk diffusion method whereas antioxidant activity was carried out using DPPH assay. Antimicrobial activity was absent in B. disticha whereas V. elaeagnifolia possessed antibacterial activity against P. mirabilis (9.0±0.2 mm) and antifungal activity against S. cerevisae(8.0±0.1 mm). Both plants possessed significant antiox
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14

Odžak, Renata, Matilda Šprung, Barbara Soldo, et al. "Quaternary salts derived from 3-substituted quinuclidine as potential antioxidative and antimicrobial agents." Open Chemistry 15, no. 1 (2017): 320–31. http://dx.doi.org/10.1515/chem-2017-0031.

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AbstractTwo series of novel ammonium salts containing the quinuclidine moiety were prepared in order to evaluate their antioxidative, antibacterial and antifungal potential. The synthesized homologues of 3-hydroxy (QOH) and 3-chloroquinuclidine (QCl) with the different N-benzyl substituents at the para-position (bromo, chloro or nitro group) were obtained in very good yields and characterized by IR and NMR spectroscopies and elemental analysis. All compounds were tested for antioxidative activity using the oxygen radical absorbance capacity (ORAC) assay and among tested samples, N-p-nitrobenzy
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15

Mustafa, Yasser Fakri, Moath Kahtan Bashir, Mahmood Khudhayer Oglah, Raghad Riyadh Khalil, and Eman Tareq Mohammed. "Bioactivity of Some Natural and Semisynthetic Coumarin Derived Compounds." NeuroQuantology 19, no. 6 (2021): 129–38. http://dx.doi.org/10.14704/nq.2021.19.6.nq21078.

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A couple of natural coumarins was identified in the seeds of two apples’ cultivars commonly known as Granny Smith and Red Delicious. The effect of the phenolic hydroxyl moieties found in these products was evaluated on the bioactivity. This evaluation included the structural alteration of these moieties into less hydrophilic ones to explore the significance of the parent moieties on the biological activity. The investigated biopotentials were antioxidant, antiproliferative, antibacterial, and antifungal effects. The antioxidant potential was investigated by detecting the ability of the natural
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Ghosh, Arghya, Parthadeb Ghosh, and Padma Chatterjee. "Evaluation of the bioactive potentialities of a diacetaldehyde terpenoid isolated from Curcuma caesia Roxb." Journal of Phytopharmacology 2, no. 4 (2013): 1–7. http://dx.doi.org/10.31254/phyto.2013.2401.

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This paper represents evaluation of the bioactive potentialities of a diacetaldehyde terpenoid isolated from Curcuma caesia Roxb. The terpenoid was identified as (2Z,2'Z)-2,2'- (3aR,10aS)- 1,3,5,8,9,9- hexamethyl- 1,2,3,3a-tetrahydrobenzo [f] azulene- 4,10 (5H,8H,9H,10aH) - diylidene) diacetaldehyde. Assessment of its antitumour activity, antifungal activity and antibacterial activity was performed using brine shrimp cytotoxicity assay, agar cup method and disc diffusion assay respectively. The antitumour, antifungal as well as antibacterial activity was promising and it showed 25 mg/ml (LC 50
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Celik, Berna Özbek, Emel Mataraci Kara, Cagla Bozkurt Guzel, et al. "Evaluation of antimicrobial and cytotoxic effects of four Turkish species of Eryngium L." Bangladesh Journal of Botany 48, no. 2 (2019): 271–78. http://dx.doi.org/10.3329/bjb.v48i2.47549.

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The antimicrobial and cytotoxic effects of various endemic and non-endemic Eryngium species from Turkey were investigated. Nine endemic and two non-endemic Eryngium species were analyzed using a microdilution assay for their antibacterial and antifungal activities. Cytotoxic activities of E. pseudothoriifolium, E. thorifolium, E. davisii, and E. falcatum, on prostate carcinoma and endometrial cancer cells were analyzed by cytotoxic activity assay. It was observed that 16 out of 22 extracts (aerial or root part) showed antibacterial activities. Fifteen out of 22 extracts showed antifungal activ
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18

Abdul, Hadi Nisar Ahmed Shahwani Tahira Bano Syed Qasim Shah. "DETERMINATION OF PHYTOCHEMICAL COMPOSITION OF HELLIOTROPIUM DASYCARPUM: ANTIBACTERIAL AND ANTIFUNGAL ASSAY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 07 (2018): 6617–21. https://doi.org/10.5281/zenodo.1318619.

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<em>The purpose of the current study is to determine the phytochemicals, antibacterial activity and antifungal activity of the plant Helliotropium dasycarpum obtained from Baluchistan province of Pakistan. Helliotropium dasycarpum which is an herb is situated in different regions of Baluchistan, Pakistan. Various solvents are applied for the extraction of the plant and its members in various studies, with Methanolic extract being the very popular solvent. When subjected to phytochemical test, it was revealed that the plant contains alkaloids, saponins, pyhtosteroles, phenols tannins, ditepenes
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Shah, Qahir, Jahangir Khan Achakzai, Muhammad Anwar Panezai, et al. "In Vitro Biological and GC-MS Analysis of Whole Plant Calotropis procera." Journal of Chemistry 2024 (May 28, 2024): 1–23. http://dx.doi.org/10.1155/2024/2012983.

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Calotropis procera is a medicinal, traditional, and therapeutic plant in Pakistan. In this research study, the biological activities, for instance, anticancer, antileishmanial, antibacterial, antifungal, anti-inflammatory, and brine shrimp lethality assay and GC-MS are studied. MTT assay, antileishmanial bioassay, microplate Alamar Blue assay, agar tube dilution method, oxidative burst assay using chemiluminescence technique, B-hatching techniques, and triple quadrupole acquisition method MS parameters were the methods used for anticancer, antileishmanial, antibacterial, antifungal, anti-infla
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20

Sakib, Sheikh Adnan, Zimam Mahmud, Md Rejaul Karim, Tania Rahman, and Md Enamul Haque. "Isolation and Characterization of Chemical Compounds from the Stem Bark Fractions of Citrus Grandis and Evaluation of Their Antimicrobial, Cytotoxic, and Antioxidant Activities." Bioresearch Communications 9, no. 2 (2023): 1320–29. http://dx.doi.org/10.3329/brc.v9i2.67089.

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Citrus grandis belongs to the Rutaceae family and is a naturally occurring citrus plant. The fractionated crude extracts of C. grandis have been studied for the investigation of its phytochemicals and allowed for the evaluation of biological activities, especially antimicrobial, cytotoxic, and antioxidant activities. At first, we assessed the antibacterial and antifungal properties using the disc diffusion method and conducted cytotoxicity screening using the brine shrimp lethality bioassay. Among the raw extracts, we isolated two compounds named CG-F3-B1 and CG-F3-B2 through column chromatogr
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D. Adinarayana, N. Annapurna, B Sathish Mohan, and Paul Douglas. "Murraya Paniculata Mediated Synthesis of Cds Nanoparticles for Potent Biomedical Applications." Journal of Advanced Zoology 44, S6 (2023): 464–70. http://dx.doi.org/10.17762/jaz.v44is6.2210.

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The leaf extract of Murraya paniculata (MPL) is used to create cadmium sulphide nanoparticles, or CdS NPs and the reducing and stabilizing agent is plant extract. A crucial capping agent in nano production is played by phytochemicals. Analytical methods such as XRD and FTIR are used to characterize CdS NPs. The biomedical applications of prepared CdS NPs were examined, including their anticancer, antifungal, and antibacterial properties. The antibacterial performance was carried out with S.flexneri, C.perfringens, S.typhimurium, and E.faecalis which were all susceptible to the antibacterial ac
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Deepthi, S., S. Srikiran, M. Satyanarayana Gupta, and Adamu Mulatu Kumara. "Synthesis and Antimicrobial Activity Assay of Nanometal Oxide-Doped Liquid Crystal." Journal of Nanomaterials 2023 (April 7, 2023): 1–7. http://dx.doi.org/10.1155/2023/5668025.

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The spread of infectious diseases across the globe as a result of numerous bacterial and fungal variations has become a serious threat to human life. A critical global situation is the need to search for antibiotic resistance and develop new treatments. The most crucial role is for academics to advise the pharmaceutical industry about substances with antimicrobial assessments. One of the challenges in implementing novel medicine delivery is the discovery of compounds having antibacterial and antifungal characteristics against Gram-positive and Gram-negative bacteria and fungi. The superiority
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Singh, Harjinder, Jayant Sindhu, Jitender M. Khurana, Chetan Sharma, and Kamal R. Aneja. "A Facile Eco-Friendly One-Pot Five-Component Synthesis of Novel 1,2,3-Triazole-Linked Pentasubstituted 1,4-Dihydropyridines and their Biological and Photophysical Studies." Australian Journal of Chemistry 66, no. 9 (2013): 1088. http://dx.doi.org/10.1071/ch13217.

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An eco-friendly one-pot five-component synthesis of novel 1,2,3-triazole-linked pentasubstituted 1,4-dihydropyridines under ultrasonic and microwave irradiation in polyethylene glycol (PEG) 400 is described. All newly synthesised compounds were evaluated for antibacterial activity, antifungal activity, antioxidant activity, and photophysical properties. Antimicrobial activity was evaluated against six microbial strains. All compounds exhibited antifungal activity against Aspergillus niger and Aspergillus flavus and moderate antibacterial activity against Gram positive bacteria (Staphylococcus
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Hsu, Yung-Heng, Yi-Hsun Yu, Ying-Chao Chou, et al. "Sustained Release of Antifungal and Antibacterial Agents from Novel Hybrid Degradable Nanofibers for the Treatment of Polymicrobial Osteomyelitis." International Journal of Molecular Sciences 24, no. 4 (2023): 3254. http://dx.doi.org/10.3390/ijms24043254.

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This study aimed to develop a drug delivery system with hybrid biodegradable antifungal and antibacterial agents incorporated into poly lactic-co-glycolic acid (PLGA) nanofibers, facilitating an extended release of fluconazole, vancomycin, and ceftazidime to treat polymicrobial osteomyelitis. The nanofibers were assessed using scanning electron microscopy, tensile testing, water contact angle analysis, differential scanning calorimetry, and Fourier-transform infrared spectroscopy. The in vitro release of the antimicrobial agents was assessed using an elution method and a high-performance liqui
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El-Zahar, Khaled Meghawry, Mubarak Eid Al-Jamaan, Faisal Rasmi Al-Mutairi, Abdallah Mohamed Al-Hudiab, Mohamed Saleh Al-Einzi, and Ahmed Abdel-Zaher Mohamed. "Antioxidant, Antibacterial, and Antifungal Activities of the Ethanolic Extract Obtained from Berberis vulgaris Roots and Leaves." Molecules 27, no. 18 (2022): 6114. http://dx.doi.org/10.3390/molecules27186114.

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This work assessed the phenolic and flavonoid components and their antioxidant, antifungal, and antibacterial effects in the ethanolic extract of barberry leaf and roots. The antibactericidal activity of root and leaf extracts against pathogenic bacteria was tested using agar diffusion and microdilution broth production for the lowest inhibitory concentration (MIC). Berberis vulgaris root and leaf extracts inhibited Staphylococcus aureus ATCC9973, Escherichia coli HB101, Staphylococcus enteritis, and Escherichia coli Cip812. The disc assay technique was used to assess the bactericidal activity
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Mayorga-Ramos, Arianna, Johana Zúñiga-Miranda, Elena Coyago-Cruz, Jorge Heredia-Moya, Jéssica Guamán-Bautista, and Linda P. Guamán. "Phytochemical Composition and Biological Properties of Macleania rupestris Fruit Extract: Insights into Its Antimicrobial and Antioxidant Activity." Antioxidants 14, no. 4 (2025): 394. https://doi.org/10.3390/antiox14040394.

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Macleania rupestris, a fruit-bearing species of the Ericaceae family, has traditionally been used for its potential medicinal properties. Background/Objectives: This study investigates the phytochemical composition and antimicrobial activity of M. rupestris fruit extract, focusing on its antibacterial, antibiofilm, and antifungal effects. Methods: M. rupestris (Kunth) A.C.Sm. berries (code: 4456, Herbario QUPS-Ecuador) were collected from the cloud forest Montano Alto, Cuenca-Ecuador, and the extract was obtained using an ethanolic-based extraction and chemically characterized. The antibacteri
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Cebi, Nur, and Azime Erarslan. "Determination of the Antifungal, Antibacterial Activity and Volatile Compound Composition of Citrus bergamia Peel Essential Oil." Foods 12, no. 1 (2023): 203. http://dx.doi.org/10.3390/foods12010203.

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Safe and health-beneficial citrus oils can be employed as natural preservatives, flavorings, antioxidants, and as antibacterial and antifungal agents in a wide variety of food products. In this research, using GC–MS methodology, the major volatile composition of Citrus bergamia EO, obtained by hydro-distillation, was determined to consist of limonen (17.06%), linalool (46.34%) and linalyl acetate (17.69%). The molecular fingerprint was obtained using FTIR spectroscopy. The antibacterial effect of C. bergamia EO at different concentrations (0.5, 1, 2.5 and 5 µg/mL) was tested against different
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Wijianto, Bambang, Hasyrul Hamzah, Annisa Larasati Nurhidayah, Guci Intan Kemuning, and Riyadh Aqilsya Amaryl Dyas. "Characterization of Onchidiid Slug (Onchidium typhae) West Kalimantan Waters as Antibacterials and Antifungal." Borneo Journal of Pharmacy 5, no. 1 (2022): 35–41. http://dx.doi.org/10.33084/bjop.v5i1.2936.

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Onchidiid slug (Onchidium typhae) is a nudibranch that coastal communities in West Kalimantan have widely used as wounds. The study aims to characterize the West Kalimantan water O. typhae as antibacterial and antifungal. The study of O. typhae was carried out in several stages: preparation and optimization, extraction by Quinn method, characterization and identification of bioactive compounds, and antibacterial and antifungal assay using the microdilution method. The result of the proximate test showed that O. typhae powder contains high protein, namely 67.68%. Phytochemical screening results
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Tariq, Ismail1* Syed Aun Muhammad2 Fareeha anwar3 Nisar ur Rehman1 Abdul Mannan1. "BIOLOGICAL SCREENING OF ENDOPHYTIC FUNGI ISOLATED FROM NERIUM OLEANDER." IAJPS,CSK PUBLICATIONS 03, no. 11 (2016): 1322–29. https://doi.org/10.5281/zenodo.184065.

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The purpose of this study was to screen and evaluate the physiochemical and biological potential of three endophytic fungi isolated from the medicinal plant Nerium oleander (Apocynaceae). Trichoderma, Penicillium and Taloromyces species, isolated from Nerium oleander, were subjected to antioxidant activity by DPPH method, total antioxidant potential by phosphomolybdic acid method and total phenolic contents by Folin’s Ciocaltue method, antibacterial, antifungal and anti-leishmanial assay. All the extracts showed significant antifungal, antioxidant and antileishminial potential. The antioxidant
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Tonea, Andrada, Mandra Badea, Liviu Oana, Sorina Sava, and Dan Vodnar. "Antibacterial and antifungal activity of endodontic intracanal medications." Medicine and Pharmacy Reports 90, no. 3 (2017): 344–47. http://dx.doi.org/10.15386/cjmed-750.

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Background and aims. The sterilization of the entire root canal system represents the main goal of every endodontist, given the fact that the control of the microbial flora is the key point of every root canal treatment. The diversity of microorganisms found inside the root canal and also the resistance of some bacterial species to intracanal medications led to a continuous development of new endodontic products. The present study focuses on the comparison of the antibacterial and antifungal properties of different endodontic products, two commercially available, one experimental plant based e
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Ravindra, Dhivare, Chaudhari Prashant, and Rajput Shankarsing. "Synthesis of Pyridine and Phenyl Succinimides by Green Pathway and Their Antimicrobial Assay." American Journal of Heterocyclic Chemistry 4, no. 1 (2018): 26–29. https://doi.org/10.11648/j.ajhc.20180401.13.

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<strong>Abstract </strong> A simple and clean green method was implemented for the preparation of different <strong><em>succinimide derivatives</em></strong> by means of the N-substituted anilines or N-substituted 2-aminopyridines with succinic anhydride with the heating in an aqueous medium. The total synthesized 3a-j compounds were evaluated against antibacterial and antifungal species.
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Prakash, Gopi, Mani Boopathy, Ramasamy Selvam, Samuel Johnsanthosh Kumar, and Kathavarayan Subramanian. "The effect of anthracene-based chalcone derivatives in the resazurin dye reduction assay mechanisms for the investigation of Gram-positive and Gram-negative bacterial and fungal infection." New Journal of Chemistry 42, no. 2 (2018): 1037–45. http://dx.doi.org/10.1039/c7nj04125j.

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Limban, Carmen, Diana Camelia Nuta, Alexandru Vasile Missir, et al. "Synthesis and Characterization of New Fluoro/Trifluoromethyl-Substituted Acylthiourea Derivatives with Promising Activity against Planktonic and Biofilm-Embedded Microbial Cells." Processes 8, no. 5 (2020): 503. http://dx.doi.org/10.3390/pr8050503.

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The aim of this study was preparation of new derivatives based on 2-((4-chlorophenoxy)methyl)-N-(arylcarbamothioyl)benzamide structure; the new compounds were characterized by IR, NMR (1H, 13C) spectroscopy, and elemental analysis. The obtained compounds were evaluated for their in vitro antimicrobial activity against planktonic and biofilm-embedded microbial cells (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans), by qualitative and quantitative assays. Some of the compounds revealed promising antibacterial and antifungal activities, wi
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Šiler, Branislav, Danijela Mišić, Jasmina Nestorović, et al. "Antibacterial and Antifungal Screening of Centaurium Pulchellum Crude Extracts and Main Secoiridoid Compounds." Natural Product Communications 5, no. 10 (2010): 1934578X1000501. http://dx.doi.org/10.1177/1934578x1000501001.

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The main principles of C. pulchellum (Sw.) Druce, secoiridoid glycosides, have been studied as potent bioactive compounds. Here we scored their content in extracts of ten populations of this species. Antibacterial and antifungal assays of the extracts and pure secoiridoid glycosides were performed against eight bacterial strains and five fungal species. Methanol extracts from both aerial parts and roots exhibited excellent antibacterial (0.05-0.2 mg mL−1) and very good antifungal (0.1-2 mg mL−1) activity. Pure secoiridoid glycosides isolated from these extracts demonstrated very strong antibac
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Scherr, Nicole, Katharina Röltgen, Matthias Witschel, and Gerd Pluschke. "Screening of Antifungal Azole Drugs and Agrochemicals with an Adapted alamarBlue-Based Assay Demonstrates Antibacterial Activity of Croconazole against Mycobacterium ulcerans." Antimicrobial Agents and Chemotherapy 56, no. 12 (2012): 6410–13. http://dx.doi.org/10.1128/aac.01383-12.

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ABSTRACTAn alamarBlue-based growth inhibition assay has been adapted for the thermosensitive and slow-growing pathogenMycobacterium ulcerans. The standardized test procedure enables medium-throughput screening of preselected compound libraries. Testing of a set of 48 azoles with known antifungal activity led to the identification of an imidazole antifungal displaying an inhibitory dose (ID) of 9 μM forM. ulcerans.
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Stappen, Iris, Jürgen Wanner, Nurhayat Tabanca, et al. "Chemical Composition and Biological Activity of Essential Oils of Dracocephalum heterophyllum and Hyssopus officinalis from Western Himalaya." Natural Product Communications 10, no. 1 (2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000131.

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The essential oils of two representatives of the Lamiaceae, Dracocephalum heterophyllum Benth. and Hyssopus officinalis L., are described for their antifungal, antibacterial, larvicidal and inect biting deterrent activities. Additionally, the chemical compositions of the essential oils, analyzed by simultaneous GC-MS and GC-FID, and odor descriptions are given. The main components of H. officinalis oil were pinocarvone, cis-pinocamphone, and β-pinene. Citronellol was found as the main compound of D. heterophyllum essential oil. Antibacterial testing by agar dilution assay revealed greater acti
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Gębarowska, Elżbieta, Jacek Łyczko, Maciej Rdzanek, et al. "Evaluation of Antimicrobial and Chemopreventive Properties and Phytochemical Analysis of Solanum nigrum L. Aerial Parts and Root Extracts." Applied Sciences 12, no. 14 (2022): 6845. http://dx.doi.org/10.3390/app12146845.

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This study evaluated in vitro antibacterial, antifungal, anticancer and antioxidant activities of methanolic leaf and root extracts from Solanum nigrum L. and determined its chemical composition. The chemical profile of S. nigrum L. extract was tested using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). Disc diffusion and microdilution assays were used for the antibacterial activities. Antifungal activity was measured using the poisoned food technique. In vitro activity on the cell culture model was assessed by MTT assay, viability measurement and by determination of c
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Chepuri, Kalyani, Chidepudi Devi Sri Lalitha Naga Tulasi, Manikantha Dunna, Chittepu Pranitha, and Vadakavila Geethikalal. "In Vitro Evaluation of Biological Activities of Three Different Medicinal Plant Extracts." Biosciences Biotechnology Research Asia 22, no. 1 (2025): 281–91. https://doi.org/10.13005/bbra/3360.

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ABSTRACT: This research evaluates the biological activities of three medicinal plants: Butea monosperma, Delonix regia, and Spathodea campanulata. These plants, belonging to the Fabaceae and Bignoniaceae families, were investigated for their antibacterial, antifungal, antioxidant, and cytotoxic properties. Phytochemicals were extracted from the flowers and leaves using methanol, ethanol, and acetone. The antibacterial and antifungal activities were assessed using a disc diffusion assay against pathogens S. epidermidis, B. cereus, E. coli, K. aerogenes, P. vulgaris, S. aureus, and C. albicans.
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Hartmann, Diego O., Karina Shimizu, Maika Rothkegel, et al. "Tailoring amphotericin B as an ionic liquid: an upfront strategy to potentiate the biological activity of antifungal drugs." RSC Advances 11, no. 24 (2021): 14441–52. http://dx.doi.org/10.1039/d1ra00234a.

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Antifungal susceptibility assays and molecular dynamics simulation studies reveal a novel cetylpyridinium amphotericin B ionic liquid formulation with dual functionality: antifungal and antibacterial activities.
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40

Sarker, A., M. Irfan Ali, T. T. Arzina, M. Lokman Hossain, M. Aminul Haque, and A. K. M. Lutfor Rahman. "Screening of Antimicrobial and Antioxidant Properties of Ethylenediamine Mono-dithiocarbamate to Overcome the Resistance of Microbes Against Existing Drugs." Journal of Science and Technology Research 4, no. 1 (2023): 183–90. http://dx.doi.org/10.3329/jscitr.v4i1.67380.

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Excellency of the medical treatment depends on the potentiality of drugs. The increase of the resistance of microbes against drugs is influencing this aspect. Dithiocarbamate has an application in medicine and biology. Therefore, we have synthesized ethylenediamine mono-dithiocarbamate ligand and explored its antimicrobial and antioxidant property. The ligand exhibited moderate antibacterial activity against 13 (thirteen) selected bacteria in disk diffusion method. It showed notable antifungal activity compared to the standard. Therefore, this ligand may be considered as a potential antifungal
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Aybek, Sumeyya Deniz, Mucahit Secme, Hasan Ilhan, Leyla Acik, Suheyla Pinar Celik, and Gonca Gulbay. "Multifaceted Applications of Zerumbone-Loaded Metal–Organic Framework-5: Anticancer, Antibacterial, Antifungal, DNA-Binding, and Free Radical Scavenging Potentials." Molecules 30, no. 14 (2025): 2936. https://doi.org/10.3390/molecules30142936.

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In the present research, metal–organic framework-5 (MOF-5) was synthesized and loaded with zerumbone (ZER@MOF-5), followed by the evaluation of its anticancer, antibacterial, antifungal, DNA-binding, and free radical scavenging potentials. The synthesized nanoparticles were characterized using X-ray diffraction, ultraviolet–visible spectroscopy, Fourier-transform infrared spectroscopy, energy-dispersive X-ray spectroscopy, and scanning electron microscopy. The in vitro anticancer activity of ZER@MOF-5 was studied in a human breast cancer cell line (MCF-7) using the CCK-8 assay. The interaction
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Altintas, Ayhan, Nurhayat Tabanca, Erno Tyihák, et al. "Characterization of Volatile Constituents from Origanum onites and Their Antifungal and Antibacterial Activity." Journal of AOAC INTERNATIONAL 96, no. 6 (2013): 1200–1208. http://dx.doi.org/10.5740/jaoacint.sgealtintas.

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Abstract Essential oils obtained by hydrodistillation (HD) and microwave-assisted HD (MWHD) of Origanum onites aerial parts were analyzed by GC and GC/MS. Thirty-one constituents representing 98.6% of the water-distilled oil and 52 constituents representing 99.6% of the microwave-distilled oil were identified. Carvacrol (76.8% HD and 79.2% MWHD) and thymol (4.7% HD and 4.4% MWHD) were characterized as major constituents in both essential oils. Separation of carvacrol and thymol was achieved by overpressured layer chromatography. HPTLC and TLC separations were also compared. Essential oils were
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Md., Hasanuzzaman, and Md. Islam Wahedul. "Antimicrobial Potency of Isolated Compounds from Syzygium cumini (L.) (Myrtaceae) root." Pharmaceutical and Chemical Journal 5, no. 2 (2018): 16–22. https://doi.org/10.5281/zenodo.13895855.

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<em>Objective</em>: To observe antibacterial, antifungal, MIC of two compounds from methanol root extract. Methodology: The powdered root extracted n-Hexane, acetone, chloroform and methanol using separating funnel. The antibacterial activity of <em>S. cumini</em> were tested against thirteen bacteria following by disc diffusion assay method and Ciprofloxacin was used as a control. Antifungal activity were tested against five pathogenic fungi and Nystatin used as control. Serial dilution technique was used for Minimum Inhibitory Concentrations (MIC). <em>Results</em>: Ciprofloxacin responsive
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Djordjevic, Aleksandra, Jelena Lazarevic, Violeta Mitic, Radosav Palic, and Gordana Stojanovic. "Antimicrobial activity of Hypericum annulatum moris and Hypericum elegans stephan ex willd. essential oils from Serbia." Chemical Industry and Chemical Engineering Quarterly 19, no. 1 (2013): 7–11. http://dx.doi.org/10.2298/ciceq120111036d.

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The in vitro antimicrobial activity of Hypericum annulatum and Hypericum elegans essential oils was evaluated against a panel of standardized bacteria and fungi using broth microdilution assay. Both essential oils showed antimicrobial activity against all the tested microorganisms. Hypericum annulatum essential oil showed better antibacterial than antifungal activity, being more effective against Pseudomonas aeruginosa and Escherichia coli while H. elegans essential oil showed no significant difference between antibacterial and antifungal activity. Antimicrobial testing of ?-pinene, ?-pinene a
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Babii, Cornelia, Mihaela Savu, Iuliana Motrescu, Lucian Mihail Birsa, Laura Gabriela Sarbu, and Marius Stefan. "The Antibacterial Synthetic Flavonoid BrCl-Flav Exhibits Important Anti-Candida Activity by Damaging Cell Membrane Integrity." Pharmaceuticals 14, no. 11 (2021): 1130. http://dx.doi.org/10.3390/ph14111130.

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Infections caused by Candida are very difficult to treat due to increasing antifungal resistance. Recent studies showed that patients with Candida infections resistant to fluconazole have very few treatment options. Therefore, finding new efficient antifungal agents is a matter of medical high priority. The aim of this study was to explore the antifungal potential of BrCl-flav-a representative of a new class of synthetic flavonoids with bromine as halogen substituent at the benzopyran core against four Candida clinical strains. Determination of minimum inhibitory concentration and minimum fung
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46

Nagababu, Penumaka, J. Naveena Lavanya Latha, P. Pallavi, S. Harish, and S. Satyanarayana. "Studies on antimicrobial activity of cobalt(III) ethylenediamine complexes." Canadian Journal of Microbiology 52, no. 12 (2006): 1247–54. http://dx.doi.org/10.1139/w06-087.

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A series of cobalt(III) mixed ligand complexes of type [Co(en)2L]+3, where L is bipyridine, 1,10-phenanthroline, imidazole, methylimidazole, ethyleimidazole, dimethylimidazole, urea, thiourea, acetamide, thioacetamide, semicarbazide, thiosemicarbazide, or pyrazole, have been isolated and characterized. The structural elucidation of these complexes has been explored by using absorption, infrared, and 1H NMR nuclear magnetic resonance spectral methods. The infrared spectral data of all these complexes exhibit a band at 1450/cm and 1560–1590/cm, which correspond to C = C and C = N, a band at 575/
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Pawaskar, S. M., and K. C. Sasangan. "IN VITRO ANTIMICROBIAL ACTIVITY OF CYNODON DACTYLON (L.) PERS. LEAF EXTRACTS. ANTIMICROBIAL ACTIVITY BY ZONE OF INHIBITION ESTIMATION." INDIAN DRUGS 52, no. 04 (2015): 37–41. http://dx.doi.org/10.53879/id.52.04.10125.

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The present study was undertaken to evaluate in vitro antimicrobial activity of the successive leaf extracts of Cynodon dactylon in petroleum ether, ethyl acetate, acetone, ethanol, methanol and water, against various gram positive &amp; gram negative bacterial strains using zone of inhibition. Both Agar well diffusion method &amp; Agar disc diffusion method were used to evaluate the antibacterial efficacy. The microorganisms used in the test were – Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Shigella flexneri, Salmonella typhi, Sal
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Bagga, Bhupesh, Savitri Sharma, Sai Jeevan Madhuri Guda, et al. "Leap forward in the treatment of Pythium insidiosum keratitis." British Journal of Ophthalmology 102, no. 12 (2018): 1629–33. http://dx.doi.org/10.1136/bjophthalmol-2017-311360.

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BackgroundPythium insidiosum is a parafungus that causes keratitis resembling fungal keratitis. This study compares outcome in a large cohort of patients with P insidiosum keratitis treated with antifungal drugs, to a pilot group treated with antibacterial antibiotics.MethodsBetween January 2014 and December 2016, 114 patients with culture positive P insidiosum keratitis were included in the study. A subset of culture isolates was tested in vitro for response to nine antibacterial antibiotics by disc diffusion and E test. Patients were treated with topical natamycin in 2014, 2015 and up until
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Qaiser, Hina, Sobia Batool, Mawra Gohar, and Sidra Moqaddes. "Evaluation of Antagonistic Action of Corn Silk Extract Towards Various Fungal and Bacterial Pathogens." Lahore Garrison University Journal of Life Sciences 3, no. 4 (2020): 224–30. http://dx.doi.org/10.54692/lgujls.2019.030467.

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Corn silk (stigma of female flower) is widely exploited for medicinal purposes against various pathogenic microorganisms. The present investigation was carried out to evaluate the antimicrobial and antioxidant properties of corn silk. In this regard, antifungal and antibacterial assays of corn silk extract prepared using microwave assisted method were carried out. The results revealed that corn silk extract possessed better antibacterial potential than antifungal potential. The antifungal assays showed similar results in comparison to positive controls. The antibacterial assays revealed that t
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Aftab, Mehwish, Noreen Mazhar, Muhammad Tariq Shah, et al. "Synthesis, characterization and biological evaluation of three new Schiff bases derived from amino acids and their Ag(I) complexes." Bulletin of the Chemical Society of Ethiopia 36, no. 1 (2022): 45–56. http://dx.doi.org/10.4314/bcse.v36i1.5.

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ABSTRACT. Three Schiff base ligands which were derived from glycine, asparagine and alanine L1, L2 and L3 were designed and used to synthesized their Ag(I) complexes. 1H NMR, FT-IR, UV-Visible and conductance techniques were used to characterize the ligands and their metal complexes. The synthesized compounds showed antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH). Schiff bases and their Ag(I) complexes were screened for antimicrobial activity, in vitro antibacterial activity against three gram negative bacteria Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi wi
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