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Journal articles on the topic 'Antibacterial gla'

Author: Grafiati

Published: 14 March 2023

Last updated: 31 July 2025

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1

Oancea, Octavia-Laura, Cristina Nicoleta Ciurea, Anca Delia Mare, Adrian Man, Ruxandra Stefanescu, and Aura Rusu. "In Vitro Evaluation of the Antibacterial Effect and Influence on the Bacterial Biofilm Formation of Glutamic Acid and Some Structural Analogues." Antibiotics 14, no. 4 (2025): 415. https://doi.org/10.3390/antibiotics14040415.

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Background/Objectives: Glutamic acid (GLA) is an essential amino acid with a key role in human metabolism. A potential involvement in anticancer therapy and possible antibacterial and anti-biofilm effects were also observed. Glutamine (GLN) and monosodium glutamate (MSG) are GLA structural derivatives for which the last two effects were evaluated, with contradictory results. Therefore, this study aimed to assess the antibacterial activity and the influence on the biofilm formation of GLA, GLN, MSG, and glutamic acid diethyl ester (GLADE) on clinically relevant bacteria. Methods: Gram-positive

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Oancea, Octavia-Laura, Șerban Andrei Gâz, Gabriel Marc, Ioana-Andreea Lungu, and Aura Rusu. "In Silico Evaluation of Some Computer-Designed Fluoroquinolone–Glutamic Acid Hybrids as Potential Topoisomerase II Inhibitors with Anti-Cancer Effect." Pharmaceuticals 17, no. 12 (2024): 1593. http://dx.doi.org/10.3390/ph17121593.

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Background/Objectives: Fluoroquinolones (FQs) are topoisomerase II inhibitors with antibacterial activity, repositioned recently as anti-cancer agents. Glutamic acid (GLA) is an amino acid that affects human metabolism. Since an anti-cancer mechanism of FQs is human topoisomerase II inhibition, it is expected that FQ-GLA hybrids can act similarly. Methods: We designed 27 hypothetical hybrids of 6 FQs and GLA through amide bonds at the 3- and 7-position groups of FQs or via ethylenediamine/ethanolamine linkers at the carboxyl group of the FQ. Hydroxamic acid derivatives were also theoretically

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Gallagher, Louise, Alanna Smith, Kevin Kavanagh, et al. "Preparation and Antimicrobial Properties of Alginate and Serum Albumin/Glutaraldehyde Hydrogels Impregnated with Silver(I) Ions." Chemistry 3, no. 2 (2021): 672–86. http://dx.doi.org/10.3390/chemistry3020047.

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Calcium alginate (CaALG) hydrogel beads and two sets of composite beads, formed from a combination of calcium alginate/propylene glycol alginate/human serum albumin (CaALG/PGA/HSA) and from calcium alginate with the quaternary ammonium salt, (3-(trimethoxysilyl)propyl)-octadecyldimethylammonium chloride (QA), (CaALG/QA), were prepared. Bovine serum albumin (BSA) was condensed with glutaraldehyde (GLA) to form a BSA/GLA hydrogel. The corresponding Ag+-containing gels of all of the above hydrogels were also formed, and slow leaching of the biocidal transition metal ion from the gels bestowed bro

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Baldwin, Susan L., Sasha E. Larsen, Valerie A. Reese, et al. "Use of GLA-nanoalum as an effective adjuvant for a therapeutic ID93 TB vaccine." Journal of Immunology 200, no. 1_Supplement (2018): 180.21. http://dx.doi.org/10.4049/jimmunol.200.supp.180.21.

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Abstract Tuberculosis (TB) caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb) reportedly killed 1.3 million people in 2016 and is the leading cause of death caused by a single infectious organism. Increasingly worrisome is the ability of Mtb to develop extensive drug resistance. According to the 2017 WHO global TB report, there were 600,000 new rifampicin-resistant cases in 2016, and almost half a million cases with multiple drug resistant (MDR) TB. The development of new host-targeted therapeutic strategies that prevent the outgrowth of resistant mutants and/or modulate th

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Kamal, Shah, Chabbra Sumit, Agrawal Neetu, et al. "Synthesis and biological evaluation of substituted benzimidazoles." Journal of Indian Chemical Society 93, Aug 2016 (2016): 1009–18. https://doi.org/10.5281/zenodo.5637615.

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Institute of Pharmaceutical Research, GLA University, Mathura-281 406, Uttar Pradesh, India <em>E-mail</em> : kamal0603@gmail.com <em>Fax</em> : 91-5662-241218 Department of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi-221 005, Uttar Pradesh, India School of Pharmacy & Research, People’s University, Bhopal, Madhya Pradesh, India <em>Manuscript received online 26 December 2015, accepted 13 March 2016</em> A novel series of 2-methyl benzimidazole and 2,6-dimethyl benzimidazole (3a-3h, 4a-4h and 5a-5b) were synthesized. These compounds were character

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Contini, Cristina, Simone Serrao, Barbara Manconi, et al. "Characterization of Cystatin B Interactome in Saliva from Healthy Elderly and Alzheimer’s Disease Patients." Life 13, no. 3 (2023): 748. http://dx.doi.org/10.3390/life13030748.

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Cystatin B is a small, multifunctional protein involved in the regulation of inflammation, innate immune response, and neuronal protection and found highly abundant in the brains of patients with Alzheimer’s disease (AD). Recently, our study demonstrated a significant association between the level of salivary cystatin B and AD. Since the protein is able to establish protein-protein interaction (PPI) in different contexts and aggregation-prone proteins and the PPI networks are relevant for AD pathogenesis, and due to the relevance of finding new AD markers in peripheral biofluids, we thought it

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Łazarski, Grzegorz. "Asperugo Procumbens: a Review of Botany, Traditional Uses, Phytochemistry and Pharmacology." Pakistan Journal of Medical and Health Sciences 15, no. 10 (2021): 3092–95. http://dx.doi.org/10.53350/pjmhs2115103092.

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Asperugo procumbens is a medicinal plant widely distributed in the world, which is commonly used in the traditional medicine of the Middle East, while currently overlooked in European pharmacopoeias. The aim of the study is to present a comprehensive overview of A. procumbens in botany, traditional medicine, phytochemistry and pharmacology according to the up-to-date data. Scientific literature on the species was collected based on publicly available databases such as: PubMed, Web of Science, Scopus, Google, Google Scholar as well as monographs and PhD theses. In traditional medicine the aeria

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Tsechoeva, Leila Sh, and Vitaly F. Bezhenar. "Determination of antimicrobial resistance genes in patients with infected miscarriage. A rapid identification and optimized empirical therapy." Journal of obstetrics and women's diseases 73, no. 5 (2024): 5–14. https://doi.org/10.17816/jowd631759.

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BACKGROUND: The infectious factor during pregnancy remains the leading cause not only of maternal mortality, but also of premature pregnancy loss and subsequent reproductive function impairment. Patients with infected miscarriage represent a special cohort in terms of complexity of clinical decision-making, while the choice of antimicrobial chemotherapy is particularly difficult in conditions of accumulation of scientific knowledge about the main microbial agents. For adequate treatment, it is essential to use all modern methods of microbiota diagnosis and conduct regular monitoring of microor

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Ustyuzhanin, Alexander V., Guzel N. Guzel N. Chistyakova, and Irina I. Remizova. "Genetic profile of antibiotic resistance of enterobacteria strains isolated from obstetrics, gynecology and pediatric patients." Bulletin of maternal and child care 1, no. 3 (2025): 72–79. https://doi.org/10.69964/bmcc-2024-1-3-72-79.

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Background. Antibiotic resistance of microorganisms is a significant problem for public health in countries around the world. Studying the structure and prevalence of genetic determinants of antibiotic resistance is a current research area that makes it possible to determine the mechanisms of resistance to antibacterial drugs.Purpose of the study. To study the genetic profile of antibiotic resistance of Enterobacteriaceae strains isolated from obstetrics, gynecology and pediatric patients.Materials and methods. The genetic profile of antibiotic resistance was determined in ESBL-producing strai

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Yasinta Moi, Maria, and Vinsensia Ulia Rita Sila. "AKTIVITAS ANTIBAKTERI BUNGA GALA-GALA MERAH (SESBANIA GRANDIFLORA L.) TERHADAP PERTUMBUHAN BAKTERI STAPHYLOCOCCUS EPIDERMIDIS." Jurnal Biogenerasi 9, no. 2 (2024): 1370–74. https://doi.org/10.30605/biogenerasi.v9i2.4370.

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Gala-gala is known to have many benefits as a medicinal plant that can cure some kinds of diseases. People in Timor Island, East Nusa Tenggara, use red gala-gala flowers as a source of vegetables and medicines to cure infectious diseases such as itching that causes abscesses. This study aims to find out the antibacterial activity of red gala-gala flower extract to inhibit the growth of Staphylococcus epidermidis bacteria. The method of antibacterial activity test used paper disk diffusion with concentrations of 20% and 40%. Antibacterial activities are shown by the presence of a halo zone arou

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Medani, Della Indah. "The Potential of Sponge-Associated Bacillus spp. as A Biocontrol Agent to Inhibit Several Bacteria from Infected Catfish (Clarias gariepinus Burch)." Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 18, no. 1 (2023): 65–73. http://dx.doi.org/10.15578/724.

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Catfish is one of the freshwater aquaculture commodities with a high level of consumption and production in Indonesia. Disease outbreaks could occur in catfish farming activities caused by pathogenic bacteria. Several species of pathogenic bacteria can cause disease in catfish, resulting in mass death. This can lead to decrease in the food quality of freshwater fishery products, especially catfish. In cultured system, aquaculture occurrence of diseases can cause severe financial losses. Catfish samples were obtained from catfish farming with clinical symptoms of reddish spots on the outside of

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Medani, Della Indah. "The Potential of Sponge-Associated Bacillus spp. as A Biocontrol Agent to Inhibit Several Bacteria from Infected Catfish (Clarias gariepinus Burch)." Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 18, no. 1 (2023): 65–73. http://dx.doi.org/10.15578/squalen.724.

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Catfish is one of the freshwater aquaculture commodities with a high level of consumption and production in Indonesia. Disease outbreaks could occur in catfish farming activities caused by pathogenic bacteria. Several species of pathogenic bacteria can cause disease in catfish, resulting in mass death. This can lead to decrease in the food quality of freshwater fishery products, especially catfish. In cultured system, aquaculture occurrence of diseases can cause severe financial losses. Catfish samples were obtained from catfish farming with clinical symptoms of reddish spots on the outside of

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Ustyuzhanin, A. V., G. N. Chistyakova, I. I. Remizova, and A. A. Makhanyok. "Genetic determinants of antibiotic resistance in enterobacteria isolated during microbiological monitoring in the perinatal center." Epidemiology and Vaccinal Prevention 22, no. 4 (2023): 49–55. http://dx.doi.org/10.31631/2073-3046-2023-22-4-49-55.

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Relevance. Currently, studies of the prevalence of antibiotic resistance and its genetic characteristics are focused primarily on the adult population, although infection with multiple drug infection has been registered as etiological agents of a general infection in obstetric and gynecological and pediatric institutions. The study of the prevalence of genetic determinants of antibiotic resistance is an important area of scientific research.Aim. To analyze the results of the studies carried out to identify the genetic determinants of antibiotic resistance of enterobacteria isolated during micr

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Falk, Shaun P., Andrew T. Ulijasz, and Bernard Weisblum. "Differential Assay for High-Throughput Screening of Antibacterial Compounds." Journal of Biomolecular Screening 12, no. 8 (2007): 1102–8. http://dx.doi.org/10.1177/1087057107308161.

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The previously described Bacillus subtilis reporter strain BAU-102 is capable of detecting cell wall synthesis inhibitors that act at all stages of the cell wall synthesis pathway. In addition, this strain is capable of detecting compounds with hydrophobic/ surfactant activity and alternative mechanisms of cell wall disruption. BAU-102 sequesters preformed β-gal in the periplasm, suggesting leakage of β-gal as the means by which this assay detects compound activities. A model is proposed according to which β-gal release by BAU-102 reflects activation of pathways leading to autolysis. The autho

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Zhao, Jing-Li, Meiping Zhang, and Hong-Li Zhou. "Microwave-Assisted Extraction, Purification, Partial Characterization, and Bioactivity of Polysaccharides from Panax ginseng." Molecules 24, no. 8 (2019): 1605. http://dx.doi.org/10.3390/molecules24081605.

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Polysaccharides are a main active substance in Panax ginseng; however, microwave-assisted extraction used to prepare P. ginseng polysaccharides (MPPG) has rarely been reported, and knowledge of the bactericidal activity of P. ginseng polysaccharides remains low. Thus, this study was designed to investigate the extraction of P. ginseng polysaccharides by using two methods—hot water extraction and microwave-assisted extraction—and compare their chemical composition and structure. In addition, their antibacterial and antioxidant activities were also determined. The data implied that P. ginseng po

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He, Feng, Guang Yang, and Longjiang Yu. "Structural Investigation of an Antibacterial Polysaccharide from Streptomyces virginia H03." Zeitschrift für Naturforschung C 65, no. 5-6 (2010): 317–21. http://dx.doi.org/10.1515/znc-2010-5-602.

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The chemical structure of a polysaccharide from the broth of cultured Streptomyces virginia H03 was investigated. There might be 1→2 and 1→4 and no 1→6 glycosidic linkages in the polysaccharide according to periodate oxidation and Smith degradation. Four fragments including 2,3,4,6-Me4-Man, 2,3,6-Me3-Gal, 2,4,6-Me3-Glc, and 3,6-Me2-Man were found in the methylated polysaccharide. Furthermore, the polysaccharide has a β-Glc(1→4)- α-Man(1→4)-α-Gal(1→3)-linked backbone and a branch at the C-2 position of (1→2)-linked mannose residues as determined by the method of nuclear magnetic resonance (NMR)

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Pham, Quoc Thiet, Hieu Trung Nguyen, Sương Thi Thu Phan, Tram Thi Quynh Doan, and Ky Minh Nguyen. "STUDY OF BIOLOGICAL ACTIVITIES OF SLENDER AMARANTH (Amaranthus lividus L.) IN GIA LAI PROVINCE." Scientific Journal of Tra Vinh University 1, no. 36 (2020): 64–70. http://dx.doi.org/10.35382/18594816.1.36.2019.317.

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Slender amaranth (Amaranthus lividus L.) is a popular plant in Gia Lai Province, with anti-cancer, antioxidant and antibacterial properties. The study presents the experimental results of biological activity of Amaranthus lividus L. collected in Gia Lai Province. Evaluation of anti-tumor activity (IC50) showed good results with EtOAc and n–hexane with extracts of 8.0 µg/ml and 11.2 µg/ml (≤ 20 µg/ml, NCI) respectively. The comparison results showed that the EtOAc extract from Amaranthus lividus L. has better antibacterial activity than the MeOH extract. However, the investigated extracts from

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Ye, Manhong, Yinhong Jiang, Qiannan Han, et al. "Probiotic Potential of Enterococcus lactis GL3 Strain Isolated from Honeybee (Apis mellifera L.) Larvae: Insights into Its Antimicrobial Activity Against Paenibacillus larvae." Veterinary Sciences 12, no. 2 (2025): 165. https://doi.org/10.3390/vetsci12020165.

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This study aimed to address the need for effective probiotics and antibacterial agents to combat American foulbrood disease in honeybees, caused by Paenibacillus larvae. In the context of declining honeybee populations due to pathogens, we isolated eight lactic acid bacteria (LAB) strains from honeybee larvae (Apis mellifera L.) and evaluated their probiotic potential and inhibitory effects against P. larvae. Methods included probiotic property assessments, such as acid and bile salt resistance, hydrophobicity, auto-aggregation, co-aggregation with P. larvae, antioxidant capacities, osmotolera

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Falk, Shaun P., James W. Noah, and Bernard Weisblum. "Screen for Inducers of Autolysis in Bacillus subtilis." Antimicrobial Agents and Chemotherapy 54, no. 9 (2010): 3723–29. http://dx.doi.org/10.1128/aac.01597-09.

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ABSTRACT We describe a primary high-throughput screen that uses the reporter strain Bacillus subtilis BAU-102 to identify antibiotics that induce autolysis. The screen measures autolysis in terms of the incipient release of recombinant Escherichia coli β-galactosidase (β-Gal) from the periplasmic space of B. subtilis owing to a loss of integrity of the cell wall. In a model screen, β-Gal release values for 79 members of a library consisting of antibiotics and related compounds were collected, sorted, and plotted as a function of rank. Inducers of autolysis, which included compounds that inhibi

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Ito, Yoshiyuki, Yasushi Kawai, Kensuke Arakawa, Yoshiko Honme, Takashi Sasaki, and Tadao Saito. "Conjugative Plasmid from Lactobacillus gasseri LA39 That Carries Genes for Production of and Immunity to the Circular Bacteriocin Gassericin A." Applied and Environmental Microbiology 75, no. 19 (2009): 6340–51. http://dx.doi.org/10.1128/aem.00195-09.

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ABSTRACT Gassericin A is a circular bacteriocin produced by Lactobacillus gasseri strain LA39. We found a 33,333-bp plasmid, designated pLgLA39, in this strain. pLgLA39 contained 44 open reading frames, including seven genes related to gassericin A production/immunity (gaa), as well as genes for replication, plasmid maintenance, and conjugative transfer. pLgLA39 was transferred from LA39 to the type strain of L. gasseri (JCM 1131) by filter mating. The transconjugant exhibited >30-fold-higher more resistance to gassericin A and produced antibacterial activity. Lactobacillus reuteri LA6, the

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Zhuravleva, Irina Yu, Aldar A. Shadanov, Maria A. Surovtseva, et al. "Which Gelatin and Antibiotic Should Be Chosen to Seal a Woven Vascular Graft?" International Journal of Molecular Sciences 25, no. 2 (2024): 965. http://dx.doi.org/10.3390/ijms25020965.

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Among the vascular prostheses used for aortic replacement, 95% are woven or knitted grafts from polyester fibers. Such grafts require sealing, for which gelatin (Gel) is most often used. Sometimes antibiotics are added to the sealant. We used gelatin type A (GelA) or type B (GelB), containing one of the three antibiotics (Rifampicin, Ceftriaxone, or Vancomycin) in the sealant films. Our goal was to study the effect of these combinations on the mechanical and antibacterial properties and the cytocompatibility of the grafts. The mechanical characteristics were evaluated using water permeability

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Xia, Yulei, та Qiwei Zhai. "IL-1β enhances the antibacterial activity of astrocytes by activation of NF-κB". Glia 58, № 2 (2009): 244–52. http://dx.doi.org/10.1002/glia.20921.

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Li, Mo, Henan Zhang, Xinyu Hu, et al. "Isolation of a New Polysaccharide from Dandelion Leaves and Evaluation of Its Antioxidant, Antibacterial, and Anticancer Activities." Molecules 27, no. 21 (2022): 7641. http://dx.doi.org/10.3390/molecules27217641.

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Dandelion, in China, has a long history as a medicinal and edible plant, and possesses high nutritional and medical value. The present study aimed to isolate a new polysaccharide (DLP-3) from dandelion leaves and to evaluate its antioxidant, antibacterial, and anticancer activities. The structure of DLP-3 was analyzed using HPLC, FT-IR, SEM, GC-MS, and NMR spectroscopy. DLP-3 mainly consisted of Man, Rha, GlcA, Glc, Gal, and Ara with molar ratios of 2.32, 0.87, 1.21, 3.84, 1.00, and 1.05, respectively, with a molecular weight of 43.2 kDa. The main linkages of DLP-3 contained (1→4)-α-d-Glc, (1→

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Na, Choon-Ki, Ga-Yeon Park, and Jee-June Song. "Preparation of Filtration Material with Adsorption/Antibacterial Property by Photografting GMA and Subsequent Chemical Modification and Its Performance Evaluation." Journal of the Korean Society for Environmental Technology 20, no. 3 (2019): 178–86. http://dx.doi.org/10.26511/jkset.20.3.5.

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Borovoy, V. Yu, M. V. Chubik, and O. V. Kazmina. "ANTIBACTERIAL PROPERTIES OF BOROSILICATE ENAMEL WITH NANOSCALE ZINC OXIDE PARTICLES." Steklo i Keramika, no. 15 (March 2023): 39–47. http://dx.doi.org/10.14489/glc.2023.03.pp.039-047.

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Glass-enamel coatings have been modified with nanosized particles, which expands the scope of their application and is a promising direction. It has been established that the introduction of nanosized zinc oxide in the amount of 0.5 wt. % into the composition of the enamel of the Na2O–B2O3–TiO2–SiO2 system imparts antibacterial properties to the coating against gram-positive and gram-negative bacteria. The meaning of the index of antibacterial activity of the surface of the enamel increases on average five times more in relation to Escherichia coli (E. coli) and six times more in relation to S

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Sulistyanti, Aprillia Dini, Emma Kamelia, Hadiyat Miko, Tritania Ambarwati, and Rena Setiana. "MENGUNYAH BUAH APEL ROYAL GALA TERHADAP PEMBENTUKAN PLAK DAN DERAJAT KEASAMAN SALIVA PADA SISWA KELAS VI SDIT ASSUNNAH KOTA CIREBON." JDHT Journal of Dental Hygiene and Therapy 2, no. 1 (2021): 27–33. http://dx.doi.org/10.36082/jdht.v2i1.214.

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Plaque and pH saliva are factors that can cause dental caries. The prevalence of caries according to RISKESDAS (2018) reached 45.3% in Indonesia. WHO (2012) states that the prevalence of caries for school children at 60%-90%. They are fond of consuming cariogenic foods that can increase the risk of caries. The Royal Gala Apple contains antibacterial that can inhibit plaque formation and have a slight acid flavor that can stimulate saliva flow. Aim: To know the influence of chewing the Royal Gala Apples to plaque formation and pH saliva in grade VI students SDIT Assunnah Cirebon. Method: Quasi

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Ha, Thi Quyen, and Thi Minh Tu Hoa. "Selection of lactic acid bacteria producing bacteriocin." Journal of Vietnamese Environment 8, no. 5 (2017): 271–76. http://dx.doi.org/10.13141/jve.vol8.no5.pp271-276.

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Lactic acid bacteria were isolated from 10 samples of the traditionally fermented foods (5 samples of Vietnamese fermented pork roll and 5 samples of the salted field cabbage) and 5 samples of fresh cow milks collected from households in Vietnam. 22 strains of lactic acid bacteria were isolated for inhibition to Lactobacillus plantarum JCM 1149. Of these, only 2 strains including DC1.8 and NC1.2 have rod shape, the others have coccus shape. 7 strains showing higher antibacterial activity were selected for checking spectrum of antibacteria with indicator bacteria consistting of Bacillus subtili

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Unalan, Irem, Stefan J. Endlein, Benedikt Slavik та ін. "Evaluation of Electrospun Poly(ε-Caprolactone)/Gelatin Nanofiber Mats Containing Clove Essential Oil for Antibacterial Wound Dressing". Pharmaceutics 11, № 11 (2019): 570. http://dx.doi.org/10.3390/pharmaceutics11110570.

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The objective of this study was to produce antibacterial poly(ε-caprolactone) (PCL)-gelatin (GEL) electrospun nanofiber mats containing clove essential oil (CLV) using glacial acetic acid (GAA) as a “benign” (non-toxic) solvent. The addition of CLV increased the fiber diameter from 241 ± 96 to 305 ± 82 nm. Aside from this, the wettability of PCL-GEL nanofiber mats was increased by the addition of CLV. Fourier-transform infrared spectroscopy (FTIR) analysis confirmed the presence of CLV, and the actual content of CLV was determined by gas chromatography–mass spectrometry (GC-MS). Our investigat

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Sherwani1, Neelam, Raeid M. M. Abed, Sergey Dobretsov, and Sheji Mary. "Antibacterial and Antifungal Activities of Cyanobacterial Strains Isolated from Hot Springs in Oman." Sultan Qaboos University Journal for Science [SQUJS] 20, no. 1 (2015): 11. http://dx.doi.org/10.24200/squjs.vol20iss1pp11-19.

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In this study, cyanobacterial microbial mats from five hot springs in Oman, namely Al Kasfah Rustaq, Al Thwara Nakhl, Al–Ali Hammam, Gala and Bowsher, were characterized using direct microscopy. Nine monoclonal cyanobacterial cultures were obtained and their extracts in butanol, dichloromethane (DCM) and hexane were screened for antibacterial and antifungal activities. Direct microscopy revealed the presence of 12 different unicellular and filamentous morphotypes, with different distribution in the various mats. Temperature seems to be one of the most important parameters that accounts for the

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Kim, Jin-Seong, Jae-Bum Park, Seung-Won Jang, et al. "Determination of Antibacterial Activity from Tricholoma matsutake Extract and Its Application to Low Salted Jeot-gal." KSBB Journal 30, no. 5 (2015): 253–56. http://dx.doi.org/10.7841/ksbbj.2015.30.5.253.

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Guyot, Nicolas, Hervé Meudal, Sascha Trapp та ін. "Structure, function, and evolution ofGga-AvBD11, the archetype of the structural avian-double-β-defensin family". Proceedings of the National Academy of Sciences 117, № 1 (2019): 337–45. http://dx.doi.org/10.1073/pnas.1912941117.

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Out of the 14 avian β-defensins identified in theGallus gallusgenome, only 3 are present in the chicken egg, including the egg-specific avian β-defensin 11 (Gga-AvBD11). Given its specific localization and its established antibacterial activity,Gga-AvBD11 appears to play a protective role in embryonic development.Gga-AvBD11 is an atypical double-sized defensin, predicted to possess 2 motifs related to β-defensins and 6 disulfide bridges. The 3-dimensional NMR structure of the purifiedGga-AvBD11 is a compact fold composed of 2 packed β-defensin domains. This fold is the archetype of a structura

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Ousaaid, Driss, Hassan Laaroussi, Meryem Bakour, Hayat Ennaji, Badiaa Lyoussi, and Ilham El Arabi. "Antifungal and Antibacterial Activities of Apple Vinegar of Different Cultivars." International Journal of Microbiology 2021 (August 7, 2021): 1–6. http://dx.doi.org/10.1155/2021/6087671.

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This study was designed to assess the antimicrobial potencies of apple vinegar against pathogenic microbes. The acidity and total phenolic content were carried out by titration with NaOH 0.1 N and the Folin–Ciocalteu method, respectively, while the spread plate method, agar well diffusion, and MIC assays were used to determine the antimicrobial activities of different vinegar samples. Acidity and phenolic content were dependent on the variety, where the highest values were observed in S2 with 4.02 ± 0.04% and 1.98 ± 0.05 mg GAE/mL for acidity and total phenolic content, respectively. The sprea

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Seweryn, Ewa, Emilia Królewicz, Kamilla Stach, and Irena Kustrzeba-Wójcicka. "Nutritional and allergenic properties of hen eggs." Postępy Higieny i Medycyny Doświadczalnej 72 (April 6, 2018): 205–14. http://dx.doi.org/10.5604/01.3001.0011.7339.

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Chicken eggs, along with cow milk, are the most important source of proteins and other valuable nutrients that are introduced to a baby`s diet. Certain components of eggs, besides nutritional, also have other biological functions. Both proteins, phospholipids or carotenoids, are bioactive components which affect the physiological processes in the human body. Regular consumption of chicken eggs rich in substances with antibacterial, anti-inflammatory, immunomodulatory and antioxidant properties may contribute to reducing the incidence of certain lifestyle diseases. Ovomucoid, as a glycoprotein

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Xie, Zhipeng, Hanqi Wei, Jiahui Meng, et al. "The Analogs of Temporin-GHa Exhibit a Broader Spectrum of Antimicrobial Activity and a Stronger Antibiofilm Potential against Staphylococcus aureus." Molecules 24, no. 22 (2019): 4173. http://dx.doi.org/10.3390/molecules24224173.

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The abuse of antibiotics has led to the emergence of multidrug-resistant bacteria, which is becoming a serious worldwide problem people have to face. In our previous study, temporin-GHa (GHa) cloned from Hylarana guentheri showed antimicrobial activity against Gram-positive bacteria. In order to improve its therapeutic potential, we used a template-based and a database-assisted design to obtain three derived peptides by replacing the histidine at both ends of GHa with lysine, which exhibited faster and stronger bactericidal activity and a broader spectrum than the parent peptide. GHaK and GHa4

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Kim, Sun-Hee, Woo-Soo Jeong, So-Young Kim, and Soo-Hwan Yeo. "Quality and Functional Characterization of Acetic Acid Bacteria Isolated from Farm-Produced Fruit Vinegars." Fermentation 9, no. 5 (2023): 447. http://dx.doi.org/10.3390/fermentation9050447.

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Acetic acid bacteria (AAB) form a bacterial film on the surface of alcoholic solutions and ferment ethanol to acetic acid while also producing bioactive compounds. To discover functional AAB for industrial use, we isolated and selected strains from farm-produced vinegars using a CaCO3-containing medium. The seven isolated strains belonged to Acetobacter cerevisiae and Acetobacter pasteurianus. These strains were tolerant to ethanol concentrations up to 12% (v/v). Acidification was seen for GHA 7, GYA 23, JGB 21-17, and GHA 20 strains at a growth temperature of 40 °C. The seven AAB isolates had

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Rashid, Mohammad, Md Tanwir Athar, Mohammed Abdelmageed, et al. "Silver Nanoparticles from Saudi and Syrian Black Cumin Seed Extracts: Green Synthesis, ADME, Toxicity, Comparative Research, and Biological Appraisal." Journal of Pharmacy and Bioallied Sciences 15, no. 4 (2023): 190–96. http://dx.doi.org/10.4103/jpbs.jpbs_381_23.

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Objective: The current study’s objective is to highlight the value of using plant resources to identify key bioactive molecules and implement green chemistry in research and development to meet market demand. Materials and Methods: The black cumin seeds (Saudi and Syria originated) were utilized to make silver nanoparticles (Ag-NPs), which were subsequently confirmed using a UV spectrophotometer and color analysis of reaction mixtures. The antibacterial activity of Ag-NPs was tested against E. coli, K. pneumoniae, and S. aureus, and antioxidant activity was measured using the DPPH assay. Swiss

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Kara, Mohammed, Amine Assouguem, Omkulthom Mohamed Al kamaly, et al. "The Impact of Apple Variety and the Production Methods on the Antibacterial Activity of Vinegar Samples." Molecules 26, no. 18 (2021): 5437. http://dx.doi.org/10.3390/molecules26185437.

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Apple vinegar is a natural product widely used in food and traditional medicine as it contains many bioactive compounds. The apple variety and production methods are two factors that play a major role in determining the quality of vinegar. Therefore, this study aims to determine the quality of apple vinegar samples from different varieties (Red Delicious, Gala, Golden Delicious, and Starking Delicious) prepared by three methods using small apple pieces, apple juice, and crushed apple, through determining the physicochemical properties and antibacterial activity of these samples. The antibacter

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Amine, Daoudi, Bammou Mohamed, Ibijbijen Jamal, and Nassiri Laila. "Antibacterial Activity of Aqueous Extracts of Anacyclus Pyrethrum (L) Link and Corrigiola Telephiifolia Pourr. From the Middle Atlas Region-Morocco." European Scientific Journal, ESJ 13, no. 33 (2017): 116. http://dx.doi.org/10.19044/esj.2017.v13n33p116.

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Aqueous extracts of Corrigiola telephiifolia and Anacyclus pyrethrum were studied in vitro for their antimicrobial properties. These plants were collected from the Central Middle Atlas region. Corrigiola telephiifolia Pourr. and Anacyclus pyrethrum (L.) Link are widely used as a natural drug for the treatment of various infectious diseases. Phytochemical screening of the plants showed the presence of flavonoids, saponins, tannins, steroids and alkaloids. The determination of the polyphenols in the aqueous extract of the two plants revealed the presence of significant amounts of polyphenols (58

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Chikalovets, Irina, Alina Filshtein, Valentina Molchanova, et al. "Activity Dependence of a Novel Lectin Family on Structure and Carbohydrate-Binding Properties." Molecules 25, no. 1 (2019): 150. http://dx.doi.org/10.3390/molecules25010150.

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A GalNAc/Gal-specific lectins named CGL and MTL were isolated and characterized from the edible mussels Crenomytilus grayanus and Mytilus trossulus. Amino acid sequence analysis of these lectins showed that they, together with another lectin MytiLec-1, formed a novel lectin family, adopting β-trefoil fold. In this mini review we discuss the structure, oligomerization, and carbohydrate-binding properties of a novel lectin family. We describe also the antibacterial, antifungal, and antiproliferative activities of these lectins and report about dependence of activities on molecular properties. Su

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Desiatkina, Oksana, Serena K. Johns, Nicoleta Anghel, et al. "Synthesis and Antiparasitic Activity of New Conjugates—Organic Drugs Tethered to Trithiolato-Bridged Dinuclear Ruthenium(II)–Arene Complexes." Inorganics 9, no. 8 (2021): 59. http://dx.doi.org/10.3390/inorganics9080059.

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Tethering known drugs to a metalorganic moiety is an efficient approach for modulating the anticancer, antibacterial, and antiparasitic activity of organometallic complexes. This study focused on the synthesis and evaluation of new dinuclear ruthenium(II)–arene compounds linked to several antimicrobial compounds such as dapsone, sulfamethoxazole, sulfadiazine, sulfadoxine, triclosan, metronidazole, ciprofloxacin, as well as menadione (a 1,4-naphtoquinone derivative). In a primary screen, 30 compounds (17 hybrid molecules, diruthenium intermediates, and antimicrobials) were assessed for in vitr

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Jakób, Michał, Jacek Lubkowski, Barry R. O'Keefe, and Alexander Wlodawer. "Structure of a lectin from the sea musselCrenomytilus grayanus(CGL)." Acta Crystallographica Section F Structural Biology Communications 71, no. 11 (2015): 1429–36. http://dx.doi.org/10.1107/s2053230x15019858.

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CGL is a 150 amino-acid residue lectin that was originally isolated from the sea musselCrenomytilus grayanus. It is specific for binding GalNAc/Gal-containing carbohydrate moieties and in general does not share sequence homology with other known galectins or lectins. Since CGL displays antibacterial, antifungal and antiviral activities, and interacts with high affinity with mucin-type receptors, which are abundant on some cancer cells, knowledge of its structure is of significant interest. Conditions have been established for the expression, purification and crystallization of a recombinant va

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Kocev, Alexander, Jacob Melamed, Vladimir Torgov, Leonid Danilov, Vladimir Veselovsky та Inka Brockhausen. "The wclY gene of Escherichia coli serotype O117 encodes an α1,4-glucosyltransferase with strict acceptor specificity but broad donor specificity". Glycobiology 30, № 12 (2020): 9003–14. http://dx.doi.org/10.1093/glycob/cwaa045.

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Abstract The O antigen of enterotoxigenic Escherichia coli serotype O117 consists of repeating units with the structure [-D-GalNAcβ1-3-L-Rhaα1-4-D-Glcα1-4-D-Galβ1-3-D-GalNAcα1-4]n. A related structure is found in E. coli O107 where Glc is replaced by a GlcNAc residue. The O117 and O107 antigen biosynthesis gene clusters are homologous and reveal the presence of four putative glycosyltransferase (GT) genes, wclW, wclX, wclY and wclZ, but the enzymes have not yet been biochemically characterized. We show here that the His6-tagged WclY protein expressed in E. coli Lemo21(DE3) cells is an α1,4-Glc

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Kukric, Zoran, Ljiljana Topalic-Trivunovic, Svetlana Pavicic, Mirjana Zabic, Snjezana Matos, and Asima Davidovic. "Total phenolic content, antioxidant and antimicrobial activity of Equisetum arvense L." Chemical Industry and Chemical Engineering Quarterly 19, no. 1 (2013): 37–43. http://dx.doi.org/10.2298/ciceq120327040k.

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The antioxidant and antimicrobial activity of Equisetum arvense L. harvested in a polluted urban area were investigated. The total phenolic content determined by a modified Folin-Ciocalteu method was 335.8 mg of GEA/g of the dried ethanol extract. Antioxidant activity determined by FRAP method was 28.7 mM Fe(II)/g of extract, whereas antioxidant activity index for stable DPPH free radicals was 3.86. The results were compared with control antioxidants (gallic acid, vitamin C, BHA and BHT). Antimicrobial activity was tested by monitoring the impact of different extract concentrations through mea

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Karima, MIKOU. "Characterization, Antioxidant, and Antibacterial Activity of Vinegar Resulting from the Natural Fermentation of Two Varieties of Apple: Gala Royal and Golden Delicious." Journal of Food and Nutrition Research 13, no. 7 (2025): 246–55. https://doi.org/10.12691/jfnr-13-7-3.

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Truong Thi, Thanh Dung, and Tri Nguyen Minh. "Biochemical compositions, antioxidant activity, and in vitro antibacterial activity of extract from wild bitter melon (Momordica charantia var. abbreviata Ser.)." Heavy metals and arsenic concentrations in water, agricultural soil, and rice in Ngan Son district, Bac Kan province, Vietnam 4, no. 2 (2021): 109–14. http://dx.doi.org/10.47866/2615-9252/vjfc.3787.

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Wild bitter melon (Momordica charantia var. abbreviata Ser.) is a type of vine that grows&nbsp;wildly in the mountains and plains in Vietnam. The main use parts of the tree are fruit, stem,&nbsp;and leaf that can be eaten as vegetables. This study aims to (1) identify several bioactive chemical&nbsp;compounds in the stems and leaves of bitter melon trees in the forests in the district of Mang Yang,&nbsp;Gia Lai province; (2) evaluate the nutrient composition, antioxidant activity, and antimicrobial&nbsp;ability of fresh juice and extract with ethanol 70&deg;. The result

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Zhu, Xucheng, Guiyan Yang, Yingbin Shen, et al. "Physicochemical Properties and Biological Activities of Quinoa Polysaccharides." Molecules 29, no. 7 (2024): 1576. http://dx.doi.org/10.3390/molecules29071576.

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Quinoa, known as the “golden grain” for its high nutritional value, has polysaccharides as one of its sources of important nutrients. However, the biological functions of quinoa polysaccharides remain understudied. In this study, two crude polysaccharide extracts of quinoa (Q-40 and Q-60) were obtained through sequential precipitation with 40% and 60% ethanol, with purities of 58.29% (HPLC) and 62.15% (HPLC) and a protein content of 8.27% and 9.60%, respectively. Monosaccharide analysis revealed that Q-40 contained glucose (Glc), galacturonic acid (GalA), and arabinose (Ara) in a molar ratio o

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Mizgina, Tatyana O., Irina V. Chikalovets, Tatyana A. Bulanova, et al. "New l-Rhamnose-Binding Lectin from the Bivalve Glycymeris yessoensis: Purification, Partial Structural Characterization and Antibacterial Activity." Marine Drugs 22, no. 1 (2023): 27. http://dx.doi.org/10.3390/md22010027.

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In this study, a new l-rhamnose-binding lectin (GYL-R) from the hemolymph of bivalve Glycymeris yessoensis was purified using affinity and ion-exchange chromatography and functionally characterized. Lectin antimicrobial activity was examined in different ways. The lectin was inhibited by saccharides possessing the same configuration of hydroxyl groups at C-2 and C-4, such as l-rhamnose, d-galactose, lactose, l-arabinose and raffinose. Using the glycan microarray approach, natural carbohydrate ligands were established for GYL-R as l-Rha and glycans containing the α-Gal residue in the terminal p

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Hasan, Reham H., and Hasan A. Hasan. "Synergism antibacterial activity for novel synthesized Schiff base ligands and semi-thiosemicarbazones with ß-diketones and 4-aminoantipyrine." Bionatura 7, no. 3 (2022): 1–11. http://dx.doi.org/10.21931/rb/2022.07.03.43.

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Schiff base ligands were synthesised in this work, the first is (Z)-2-((Z)-3-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imino)-1,3-diphenylpropylidene) hydrazine-1-carboxamide, the second is (Z)-2-((1E,5Z,6E)-5-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imino)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-dien-3-ylidene)hydrazine-1-carbothioamide. The Schiff base ligands both were synthesised using the same method (the single pot reaction), using EtOH as the reaction medium and GAA as the catalyst in fixed temperature at 70 0C and reflux for 6 hrs. The starting mate

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Chainikova, I. N., Yu V. Filippova, B. A. Frolov, et al. "MILIACINE INFLUENCE ON THE BIOFILM FORMATION OF BACTERIA." Journal of microbiology, epidemiology and immunobiology, no. 4 (August 28, 2016): 3–9. http://dx.doi.org/10.36233/0372-9311-2016-4-3-9.

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Aim. The comparative estimation of miliacine influence on the biofilm formation of bacteria. Materials and methods. The objects of investigation were the clinical isolates of Salmonella enteritidis (28), Salmonella typhimurium (24), Klebsiella pneumoniae (8), Pseudomonas aeruginosa (8) and reference strains of lactobacilli (5) and bifidobacteria (3). Miliacin was obtained from crystals of millet oil. Antibacterial activity of miliacin was detected by the method of serial dilutions. For investigation of biofilms miliacin in 100 and 50 mkg/ml concentrations was used. Miliacin was diluted in Twin

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Bastas, Kubilay Kurtulus. "Management of Erwinia amylovora by Potential Bio-Pesticides in vitro and in vivo Conditions." Turkish Journal of Agriculture - Food Science and Technology 8, sp1 (2020): 38–45. http://dx.doi.org/10.24925/turjaf.v8isp1.38-45.3933.

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Erwinia amylovora, the causative agent of fire blight disease, threatens a lot of species of the Rosaceae family. Antibiotics and copper compounds in chemical applications are most frequently are applied, but these can be phytotoxic and cause resistant strains of the pathogen. In our experiments, 20 herbal materials were tested for their antimicrobial effectiveness against the fire blight pathogen in vitro and in planta. The air-dried plants ground into fine powder and extraction was performed at room temperature by maceration with 80% (v/v) methanol/distilled water. The minimum inhibitory con

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