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Journal articles on the topic 'Antibiotic Cefotaxime'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

R., Shinde A., Mohite R. V., and Shinde R. V. "PATTERN OF ANTIBIOTICS UTILIZATION IN NEONATAL SEPTICEMIA: A CROSS-SECTIONAL STUDY FROM RURAL TERTIARY CARE HOSPITAL WESTERN MAHARASHTRA, INDIA." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 3 (2017): 60. http://dx.doi.org/10.22159/ijpps.2017v9i3.16210.

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Objective: To assess the quantification of use of antibiotics and to find out empiric antibiotic regimen practiced for neonatal sepsis in rural tertiary health care centre.Methods: A hospital, record based cross-sectional study was conducted in Neonatal Intensive Care Unit(NICU) at tertiary care hospital located in western Maharashtra, India. The study was planned during the year 2011-12 among 84 neonates with sepsis. Data were collected by using proforma includes demographic details, antibiotic prescriptions and relevant information.Results: Among the total 84 neonates, max, 60.71% had a hist

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Rasschaert, Geertrui, Daan Van Elst, Lander Colson, et al. "Antibiotic Residues and Antibiotic-Resistant Bacteria in Pig Slurry Used to Fertilize Agricultural Fields." Antibiotics 9, no. 1 (2020): 34. http://dx.doi.org/10.3390/antibiotics9010034.

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Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples. These samples were also studied for the presence of Salmonella and for E. coli resistant to meropenem, colistin, ciprofloxacin, or cefotaxim. The obtained isolates were further tested for antibacterial susceptibility. No antibiotic residues were detected in four samples, whereas in the other samples, up to 12 antibiotics were found. The most frequent

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Husni, Amin, Hardjono Abdoerrachman, and Arwin Akib. "Antibiotic profile in pediatric wards, Department of Child Health, Cipto Mangunkusumo Hospital." Paediatrica Indonesiana 44, no. 2 (2016): 46. http://dx.doi.org/10.14238/pi44.2.2004.46-50.

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Introduction The medical profession has currently come to a con-clusion that the major problem in the future is failure of treatmentdue to antibiotic-resistant microorganisms.Objective The aim of this study was to determine the profile ofantibiotics used in the Pediatric Wards of Department of Child Health,Medical School, University of Indonesia, Cipto Mangunkusumo Hos-pital, Jakarta.Methods A descriptive retrospective study was conducted on all pa-tients hospitalized in the Pediatric Wards of Department of Child Health,Medical School, University of Indonesia, Cipto Mangunkusumo Hos-pital duri

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Paramitadevi, Yudith Vega, Cindy Rianti Priadi, Iftita Rahmatika, Andriansjah Rukmana, and Setyo Sarwanto Moersidik. "Resistance profile of Escherichia coli isolated from stool, feed, and compost sources to antibiotics in Sukabumi." E3S Web of Conferences 485 (2024): 07001. http://dx.doi.org/10.1051/e3sconf/202448507001.

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Antibiotic-resistant E. coli is a growing concern in various settings, but environmental studies are rare compared to clinical research on human and animal health. This study aimed to identify the prevalence of E. coli bacteria resistant to different antibiotics in the environment by examining E. coli resistant to cefotaxime isolated from ruminant stool, feed, and compost. The phenotyping test was conducted through antibiotic susceptibility test using Kirby-Bauer disk-diffusion method, followed by the One-Way variance (ANOVA) analysis of the antibiotic susceptibility test results. Of the 12 is

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Admaja, Wika, Faresa Amelia, Eko Yudha Prasetyo, and Anggi Restyana. "Analisis Minimalisasi Biaya Terapi Antibiotik Ceftriaxone dan Cefotaxime Pada Pasien Pneumonia di Instalasi Rawat Inap RSUD Kabupaten Kediri." Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) 6, no. 01 (2024): 10. http://dx.doi.org/10.30587/herclips.v6i01.7662.

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Pneumonia is an infection caused by pathogenic microorganisms such as microbes, bacteria, fungi and viruses that cause inflammation of the lung tissue. The prevalence of pneumonia has increased every year. The first-line therapy used at the Kediri District Hospital is the use of ceftriaxone and cefotaxime antibiotics. Decision making on antibiotic use has an influence on the amount of medical costs incurred by patients. This study aims to determine which antibiotics are more cost-minimal and whether there is a significant difference between the use of ceftriaxone and cefotaxime antibiotic ther

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Langi, Regita, Widya A. Lolo, and Imam Jayanto. "ANALISIS EFEKTIVITAS BIAYA PENGGUNAAN ANTIBIOTIK PADA PASIEN SEPSIS DI RUMAH SAKIT SILOAM MANADO." PHARMACON 8, no. 4 (2019): 836. http://dx.doi.org/10.35799/pha.8.2019.29360.

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ABSTRACT Sepsis is a systemic disease that is often life-threatening in hospitals. Treatment with antibiotics is one of the important factors supporting the success of sepsis treatment. Because of the variety of antibiotic therapy given to sepsis patients, it is necessary to do a cost-effectiveness analysis to find out which treatment therapies are more cost-effective. This study aims to find out more cost-effective therapies between the treatment of cefotaxime and ceftazidim antibiotics in sepsis patients at Siloam Hospital Manado using descriptive research methods by retrospective retrieval

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Shaaban, Maher Ali Abdul Hussein, Muqtada Hamid Abd Yasser, Zahraa salim saed Abed, and Abdulaziz Younis Mahmood Ahmed. "EFFECT OF CEFOTAXIME ON ESCHERICHIA COLI ISOLATED FROM URINARY TRACT INFECTION." European Journal of Medical Genetics and Clinical Biology 1, no. 7 (2024): 233–43. http://dx.doi.org/10.61796/jmgcb.v1i7.779.

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This study aims to detect the effect of cefotaxime antibiotic on Escherichia coli bacteria isolated from urinary tract infections. 27 clinical samples were collected from the urine of women with urinary tract infections caused by Escherichia coli bacteria under the supervision of a specialist doctor at Al-Rifai General Hospital in Al-Rifai District / Dhi Qar Governorate. Escherichia coli bacteria have been diagnosed by conventional methods, which have confirmed infection with Escherichia coli. A drug susceptibility test was conducted for bacterial isolates of E. coli to the antibiotic cefotaxi

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Laelasari, Ninda, Maratun Shoaliha, Fauziah H Wada, Ashar Prima, and Sandeep Poddar. "Cost Effectiveness Analysis Treatment of Pediatric Pneumonia Antibiotic Ceftriaxon and Cefotaxime at Dr. Chasbullah Abdulmadjid Hospital." ICMST 19, s9 (2023): 102`—106. http://dx.doi.org/10.47836/mjmhs.19.s9.15.

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Introduction: Pneumonia is inflammation in the lung parenchyma. Inflammation occurs due to infection by various organisms like bacteria, viruses, and others. This infection eventually causes the emergence of several signs and symptoms. Ceftriaxone and cefotaxime are antibiotics that are commonly and effectively used in the treatment of pneumonia. Methods: The purpose of this study is to determine the total cost of pneumonia treatment provided during hospitalization at RSUD Bekasi City. This research uses the method descriptive research with data retrieval retrospectively. The sample in this re

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Amin, Aalia. "The Detection of ESBL-Producing Escherichia coli in Various Clinical Sample Using 3rd Generation Cephalosporin by Different Diffusion Methods." International Journal of Current Microbiology and Applied Sciences 13, no. 6 (2024): 59–68. http://dx.doi.org/10.20546/ijcmas.2024.1306.006.

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This study aimed to determine the prevalence of extended spectrum of beta lactamases (ESBLs), to compare two antibiotic i.e Cefotaxime & Ceftazidime by different phenotypic methods for ESBL con?rmation and to evaluate the antibiotic resistance patterns among ESBL-producing Escherichia coli. Total no. of E.coli isolates were obtained from various clinical samples. They were subjected for the antibiotic susceptibility pattern by Kirby bauer disc diffusion method. 3rd generation cephalosporin resistant isolates were detected for ESBL production. In our isolates we have found increased percent

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Lee, Karen, Usamah Afiff, Safika Safika, and Titiek Sunartatie. "Antimicrobial sensitivity of most commonly isolated bacteria from feline upper respiratory infection." ARSHI Veterinary Letters 5, no. 3 (2022): 55–56. http://dx.doi.org/10.29244/avl.5.3.55-56.

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In cats, upper respiratory tract infection (URI) can be associated with primary or secondary bacterial infection and is generally treated with antimicrobials. Antimicrobial use can be inappropriate, and overuse. There are no detailed protocols for treatment, such as those available for human treatment. This study aimed to determine the antimicrobial sensitivity of the most isolated bacteria in cats that infected with the URI. Isolation and identification of bacteria in samples of cats infected with the URI were then continued with the antibiotic sensitivity test for amoxicillin, doxycycline, t

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Alfarizi, Gilang Rizki, Fransisca Gloria, Cindy Wahyu Ramadhani, Desti Busdha, and Sri Suwarni. "Evaluation of Antibiotic Use in Pediatric Pneumonia Patients Using ATC/DDD and Gyssens Methods at Primaya Hospital Semarang." Jurnal Ilmu Farmasi dan Farmasi Klinik 21, no. 2 (2024): 173–81. https://doi.org/10.31942/jiffk.v21i2.9460.

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Antibiotic resistance rates may increase due to inappropriate antibiotic use in pediatric bronchopneumonia; antibiotic treatment's effectiveness can be assessed qualitatively and quantitatively. Data were collected retrospectively and analyzed descriptively using the ATC/DDD and Gyssens methods. This study was observational; data were collected from January to December 2022 at Primaya Hospital Semarang City with 41 patient health medical record samples. The results showed that the most commonly used antibiotics were ceftriaxone and cefotaxime, with ceftriaxone used by 28 patients (68.3%) at do

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Muslim, Zamharira, Putri Widelia Welkriana, and Regita Pratiwi Mahardika. "Antibiotic Sensitivity Of Acute Respiratory Infection Patients In Bhayangkara Hospital Bengkulu." SANITAS: Jurnal Teknologi dan Seni Kesehatan 11, no. 1 (2020): 31–40. http://dx.doi.org/10.36525/sanitas.2020.3.

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The high incidence of antibiotic resistance in the treatment of infections today is very worrying. The main therapy in patients with acute respiratory infections (ARI) is using antibiotics. This study aims to determine the sensitivity of several antibiotics to the bacteria that cause ARI. The design of this study is quasi-experimental. This sensitivity testing uses the disc diffusion method (Kirby Bauer). The antibiotics used are Ampicillin and Cefotaxime. The results obtained are that the antibiotic Ampicillin resistant by 86.26% and 13.63% are still sensitive to the bacteria that causes ARI.

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Satari, Hindra Irawan, Agus Firmansyah, and Theresia Theresia. "Qualitative evaluation of antibiotic usage in pediatric patients." Paediatrica Indonesiana 51, no. 6 (2011): 303. http://dx.doi.org/10.14238/pi51.6.2011.303-10.

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Background Antibiotics are among the most commonly prescribed drug for pediatric patients. Inappropriate use of antibiotics can increase morbidity, mortality, patient cost and bacterial antibiotic resistence. Antibiotic uses can be evaluated quantitatively and qualitatively.Objective To qualitatively evaluate antibiotic use in patients using Gyssens algorithm.Methods We performed a descriptive, retrospective study of matient medical records of those admitted to the pediatric ward from January 1 – June 30, 2009. Records were screened for patient antibiotic use, followed by qualitative evaluatio

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Wiebke, Beatriz, Fabricio Ferreira, Giancarlo Pasquali, Maria Helena Bodanese-Zanettini, and Annette Droste. "Influence of antibiotics on embryogenic tissue and Agrobacterium tumefaciens suppression in soybean genetic transformation." Bragantia 65, no. 4 (2006): 543–51. http://dx.doi.org/10.1590/s0006-87052006000400002.

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The influence of different antibiotic treatments in soybean genetic transformation was evaluated. First, an assay was performed to verify how different antibiotic treatments affect soybean embryogenic tissues. The effect of carbenicillin at 500 mg L-1 was genotype-dependent. This antibiotic did not affect embryo survival of cv. IAS5, but a three-fold increase of embryo proliferation was observed for cv. Bragg, when compared to the control. On the other hand, cefotaxime at 350 and 500 mg L-1 caused death of embryogenic tissues of both cultivars. Finally, the association of cefotaxime (250 mg L-

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Wardati, Yulia, Dytha Andri Deswat, and Zainal Muttaqin. "Pharmacoeconomic Analysis Of Using Cephalosporin Group In Appendicitis Prophylactic In Rumah Sakit Umum Daerah Subang." JURNAL ILMU KEFARMASIAN INDONESIA 16, no. 2 (2018): 200. http://dx.doi.org/10.35814/jifi.v16i2.441.

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The administration of cephalosporin group antibiotics in patients with post-surgical appendicitis is necessary to prevent postoperative wounds. This pharmacoeoconomic study was conducted retrospectively in the period of 1 January to 31 December 2015 in RSUD Subang for the purpose of determining the effectiveness of drugs and the cost of antibiotic use of ceftriaxone, cefotaxime, and ceftizoxime injection by Cost Effectiveness Analysis method. The subject of the patient was 78 people. Based on Average Cost Effectiveness Ratio (ACER), the smallest value is ceftriaxone Rp 729.124 / day, while the

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Ayub, Aqeela, Tasleem Bano, Amna Khalid, Muhammad Khalid Masood, Hamna Ayub, and Hashim Raza Syed. "Outcome of Bacterial Meningitis in Children age 1 Month – 12 Years in a Public st SectorHospital Treated with 1 line Antibiotics." Esculapio 18, no. 4 (2022): 403–7. http://dx.doi.org/10.51273/esc22.251841.

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Objective: To determine the effectiveness of using first line antibiotics for the treatment of acute bacterial meningitis in children admitted in a public sector hospital and assessing its outcome with the help of data by need for using second line antibiotics therapy and length of stay in hospital. Method: This Crosssectional study was conducted at department of Pediatrics, Pakistan Institute of Medical Sciences, Islamabad over a period of 6 months from January 2019 to July 2019. All children between the age of 1 month – 12 years, of both genders admitted in pediatric ward with acute bacteria

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Chuang, Yin-Ching, Wen-Chien Ko, Shan-Tair Wang, et al. "Minocycline and Cefotaxime in the Treatment of Experimental Murine Vibrio vulnificus Infection." Antimicrobial Agents and Chemotherapy 42, no. 6 (1998): 1319–22. http://dx.doi.org/10.1128/aac.42.6.1319.

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ABSTRACT We conducted an in vivo study with the mouse model of Vibrio vulnificus infection to evaluate the efficacies of therapy with minocycline or cefotaxime alone and in combination. V. vulnificus was introduced subcutaneously into the area over the right thigh. The inoculum size ranged from 1.0 × 103to 1.2 × 108 CFU from experiment to experiment but was constant for all animals in the same experiment. Antibiotics were given intraperitoneally 2 h after the bacteria were inoculated. In experiments 1 to 4, the standard dose for humans was used to treat the infection, while in experiment 5, fi

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Rizqullah, Rifqi, Eustachius Hagni Wardoyo, Adelia Riezka Rahim, Rosyunita Rosyunita, Nurmi Hasbi, and I. Nyoman Yudayana Indratama. "Identification of Antibiotic-Resistant Gram Positive Bacteria from Broiler Caecum in The Slaughterhouse of Mataram City." Jurnal Biologi Tropis 25, no. 1 (2025): 551–62. https://doi.org/10.29303/jbt.v25i1.8466.

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The subtherapeutic use of antibiotics as Antimicrobial Growth Promoters (AGPs) in broilers has accelerated Antimicrobial Drug Resistance (AMR) in gut microbiota, posing a global threat. This study aimed to analyze the population, morphology, catalase test results, and antibiotic sensitivity of erythromycin and vancomycin to cefotaxime-resistant Gram-positive bacteria in the caecum of broilers from Mataram City slaughterhouses. Using exploratory descriptive method, five caecum samples were analyzed by Total Plate Count (TPC) on Man Rogosa Sharpe Agar (MRSA) media with and without cefotaxime, an

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Kusumawati, Diah Retno. "Relationship Of Gentamycin Antibiotic Exposure To: Escherichia Coli Bacteria Resistant To Antibiotic Gentamycin And Escerichia Coli ESBL In Vitro." International Islamic Medical Journal 3, no. 1 (2022): 27–35. http://dx.doi.org/10.33086/iimj.v3i1.2138.

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Background: The development of bacteria that have been resistant to antibiotics can complicate the treatment process. Either causes of antibiotic resistance is inappropriate use of antibiotics. Gentamycin is an aminoglycoside-derived antibiotic which its role is very significant for gram-negative bacteria. Repeated use of gentamycin antibiotics can cause changes the effectiveness of gentamycin so that non ESBL-Gentamycin susceptible Escherichia Coli will change into ESBL-Gentamycin resistant Escherichia coli. Objective: This study aims to prove that repeated exposure to Gentamycin in vitro wil

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B., Srinivasa, and Basavaraj C. Kotinatot. "Drug utilization of antibiotics in post-operative cesarean section inpatients in tertiary care hospital: a prospective observational study." International Journal of Basic & Clinical Pharmacology 9, no. 6 (2020): 859. http://dx.doi.org/10.18203/2319-2003.ijbcp20202182.

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Background: The aim of this study is to evaluate the pattern and rational use of antibiotics in post-operative caesarean section (CS) inpatients in tertiary care teaching hospital, BIMS Belagavi.Methods: This cross sectional prospective observational study was conducted from December 2019 to February 2020, prior permission from institutional ethics committee was taken. Detailed data of post-operative caesarean section (CS) inpatients including age, diagnosis, line of management, complications and any adverse effects if occurred during the study was collected and entered in a specially designed

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Keskitalo, M., A. Pohto, M. L. Savela, J. P. T. Valkonen, E. Pehu, and J. Simon. "Control of Bacteria and Alteration of Plant Growth in Tissue Cultures of Tansy (Tanacetum vulgare L.) Treated with Antibiotics." HortScience 31, no. 4 (1996): 631e—631. http://dx.doi.org/10.21273/hortsci.31.4.631e.

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Ten bacteria were isolated from the in vitro shoot cultures of different tansy (Tanacetum vulgare) genotypes. All isolates were Gram-negative. Five isolates belonged to Enterobacteriaceae, three isolates were strains of fluorescent Pseudomonas, and two isolates were strains of other aerobic bacteria. The combined treatment with gentamicin (50 mg·L–1) and rifampicin (25 mg·L–1) prevented the growth of all bacteria, whereas none of the antibiotics (ampicillin, cefotaxime, rifampicin, gentamicin, or streptomycin) controlled all bacteria when used alone. The antibiotics ranged based on their incre

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Citraningtyas, Gayatri, Ranny Inggrid Ruru, and Amelia Nalang. "Cost Effectiveness Analysis Using Antibiotics of Cefixime and Cefotaxime for Diarrhea Patients at X Hospital in 2017." JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) 8, no. 4 (2019): 145. http://dx.doi.org/10.22146/jmpf.36258.

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Diarrhea is a disease characterized by a change in the shape and consistency of stools, from soft to liquid, and increased frequency of bowel movements, which happen three times or more in a day. Different use of antibiotics by patients results in patient’s medical cost increase. The use of expensive antibiotics does not guarantee the effectiveness of patient care, therefore a research needs to be done to determine which antibiotic therapy is more cost effective between cefixime and cefotaxime antibiotics in hospitalized diarrhea patients in X hospital. This research was descriptive research w

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Rahmi, Sofia. "- KAJIAN PENGGUNAAN ANTIBIOTIK PADA Neonatus Intensif Care Unit DI RUMAH SAKIT UMUM SEMBIRING DELI TUA." Jurnal Penelitian Farmasi & Herbal 7, no. 1 (2024): 36–41. https://doi.org/10.36656/jpfh.v7i1.1997.

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Infancy is the period after birth before 59 months of age. Death in infants can be caused by several things, and one of the biggest causes of death in infants is due to infection. increased risk of therapeutic failure, one of the impacts that need to be aware of is the potential for resistance when the antibiotics given cannot reach the minimum level to inhibit growth or kill bacteria. The occurrence of problems in NICU patients due to antibiotic use caused by antibiotic use. This research method is by collecting data obtained from medical records and families of patients treated at Sembiring

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Dyagelev, Mikhail. "Measurement of pollutant concentration in the model solution." E3S Web of Conferences 389 (2023): 02013. http://dx.doi.org/10.1051/e3sconf/202338902013.

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This work presents the results of the work on the determination of a pollutant in a model solution, the antibiotic cefotaxime, using the spectrophotometric method. In several series of experiments, the minimum concentrations of cefotaxime in model solutions that can be detected with a spectrophotometer PE-5400 UV were established; a feature of cefotaxime was revealed - the increase of the optical density peak in the samples when the pH is shifted to an acidic environment, especially at pH values from 0.2 to 2.0. The obtained values of optical density and absorption spectra of the model solutio

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Rosnarita, Intan Adevia, Akhtyasin Akhyasin, and Sintia Kusuma Dewi. "PERBANDINGAN EFEKTIVITAS CEFOTAXIME DAN CEFTRIAXONE PADA PASIEN RAWAT INAP PEDIATRI DENGAN PNEUMONIA." IJF (Indonesia Jurnal Farmasi) 9, no. 1 (2024): 35–43. http://dx.doi.org/10.26751/ijf.v9i1.2425.

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The prevalence of pneumonia for pediatrics in Indonesia is quite high. This condition is a concern for clinicians, especially pharmacists in handling the treatment of pneumonia in pediatrics. Treatment of pneumonia for pediatrics needs antibiotic therapy such as cefotaxime and ceftriaxone. This study aims to compare the effectiveness of the use of antibiotics cefotaxime and ceftriaxone in pediatric pneumonia patients at the inpatient installation of RSI Sunan Kudus Period February-April 2021. This study is a non-experimental research study with an observational analytic character, with purposi

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Kampf, Günter. "Biocidal Agents Used for Disinfection Can Enhance Antibiotic Resistance in Gram-Negative Species." Antibiotics 7, no. 4 (2018): 110. http://dx.doi.org/10.3390/antibiotics7040110.

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Biocidal agents used for disinfection are usually not suspected to enhance cross-resistance to antibiotics. The aim of this review was therefore to evaluate the effect of 13 biocidal agents at sublethal concentrations on antibiotic resistance in Gram-negative species. A medline search was performed for each biocidal agent on antibiotic tolerance, antibiotic resistance, horizontal gene transfer, and efflux pump. In cells adapted to benzalkonium chloride a new resistance was most frequently found to ampicillin (eight species), cefotaxime (six species), and sulfamethoxazole (three species), some

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Dini Indriani, Musa Fitri Fatkhiya, and Gita Ulistanti. "Analisis Efektivitas Biaya Penggunaan Antibiotik Seftriakson dan Sefotaksim Pada Terapi Demam Tifoid di RSUD Dr.M.Ashari Pemalang." Jurnal Medika Nusantara 1, no. 2 (2023): 240–51. http://dx.doi.org/10.59680/medika.v1i2.455.

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Typhoid fever is a disease caused by salmonella typhi bacteria whose main treatment is antibiotics. Antibiotic costs are more than 50% of the hospital pharmacy budged so that cost-effectiveness analysis is needed to improve efficiency or appropriate costs and effectiveness (treatment result). This study is an observation study on typhoid fever patients at Dr.M.Ashari Pemalang in January-Desember 2022. The sampling technique used purposive sampling and met the inclusion criteria of 20 samples. Data will be presented in tabular from on the data collection sheets and analyzed using the ACER formu

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Willerton, Laura, Jay Lucidarme, Andrew Walker, et al. "Antibiotic resistance among invasive Neisseria meningitidis isolates in England, Wales and Northern Ireland (2010/11 to 2018/19)." PLOS ONE 16, no. 11 (2021): e0260677. http://dx.doi.org/10.1371/journal.pone.0260677.

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Invasive meningococcal disease (IMD), caused by Neisseria meningitidis, can have a fatality rate as high as 10%, even with appropriate treatment. In the UK, penicillin is administered to patients in primary care whilst third generation cephalosporins, cefotaxime and ceftriaxone, are administered in secondary care. The first-choice antibiotic for chemoprophylaxis of close contacts is ciprofloxacin, followed by rifampicin. Immunocompromised individuals are often recommended antibiotic chemoprophylaxis and vaccination due to a greater risk of IMD. Resistance to antibiotics among meningococci is r

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Song, Gao, Rong Li, Na Yang, Meng-Qun Cheng, and Cai-Qiong Zhang. "Cefotaxime-associated encephalopathy in peritoneal dialysis patients: A case report." Medicine 104, no. 25 (2025): e42915. https://doi.org/10.1097/md.0000000000042915.

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Rationale: Cefotaxime is a widely used 3rd-generation cephalosporin antibiotic that is primarily excreted through urine. Third-generation cephalosporins (e.g., ceftazidime, ceftriaxone) and the 4th-generation cefepime are associated with neurological complications. Although cephalosporin-associated encephalopathy (CAE) is well-documented, cases specifically induced by cefotaxime remain remarkably rare. To our knowledge, this is the 1st documented case of cefotaxime-induced CAE in a patient undergoing peritoneal dialysis. Patient concerns: A 72-year-old female patient on peritoneal dialysis dev

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Syafitri, Dina Mulyana, and Yerlina. "ANALISIS PENGGUNAAN ANTIBIOTIK PADA PASIEN RAWAT INAP BEDAH DI RSUD RAJA AHMAD TABIB." Jurnal Penelitian Farmasi Indonesia 13, no. 1 (2024): 65–72. http://dx.doi.org/10.51887/jpfi.v13i1.1897.

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Penyakit infeksi termasuk dalam sepuluh besar penyakit terbanyak di Indonesia. Tingginya mortalitas dan morbiditas akibat penyakit infeksi salah satunya disebabkan oleh ketidaktepatan penggunaan antibiotik. Penggunaan antibiotik yang tidak bijak dapat memicu timbulnya masalah resistensi. Hubungan resistensi antibiotik tidak dapat dipisahkan dengan ketepatan penggunaan antibiotik. Penelitian ini adalah penelitian deskriptif analitik yang dilakukan secara retrospektif pada pasien rawat inap bedah di RSUD Raja Ahmad Tabib Provinsi Kepulauan Riau periode Januari – Agustus 2022, dengan tujuan untuk

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Zyablov, A. N., and A. A. Shapovalova. "Determination of the residual amounts of cefotaxime in liquid media using piezoelectric sensors." Industrial laboratory. Diagnostics of materials 88, no. 2 (2022): 15–20. http://dx.doi.org/10.26896/1028-6861-2022-88-2-15-20.

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The goal of the study is to develop a piezoelectric sensor based on a molecularly imprinted polymer (MIP) for the determination of cefotaxime in liquid media. To obtain an antibiotic-selective sensor, the electrode surface of was modified with a molecularly imprinted polymer. A pre-polymerization mixture was prepared using a copolymer of 1,2,4,5-benzoltetracarboxylic acid and 4,4’-diaminodiphenyloxide, and an aqueous solution of cefotaxime in a ratio of 1:1. Then a two-stage thermoimidization was carried out in a drying cabinet at a temperatures of 80 and 120°C. After that, the sensor was cool

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Kukushkin, German V., M. V. Zhuravleva, L. P. Sviridkina, and D. E. Yurov. "HYALURONIDASE: AN EXPERIMENTAL CONFIRMATION OF THE PROPERTIES OF THE ENDOLYMPHATIC CONDUCTOR." Medical Journal of the Russian Federation 25, no. 1 (2019): 40–43. http://dx.doi.org/10.18821/0869-2106-2019-25-1-40-43.

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One of the major achievements of contemporaneous pharmacology is the clinical implementation of the agents (the so called “endolymphatic conductors”) that allow for targeted delivering of antibiotic into the lymphatic system. Their use provides the basis for the lymphotropic treatment method that has been implemented into various areas of medical practice. Hyaluronidase is the most known agent used for this purpose. It has been shown that its preliminary administration before the injection of an antibiotic can improve clinical efficacy of the treatment; however, there is a need in the experime

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Kukushkin, German V., M. V. Zhuravleva, L. P. Sviridkina, and D. E. Yurov. "THE EFFECT OF UNFRACTIONATED HEPARIN ON LYMPHATIC DRAINAGE OF TISSUES AND PHARMACOKINETICS OF CEFOTAXIM." Medical Journal of the Russian Federation 25, no. 3 (2019): 181–84. http://dx.doi.org/10.18821/0869-2106-2019-25-3-181-184.

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Over the past decades, methods of targeted delivery of drugs to target tissues through the lymphatic system have been intensively developed, which makes it possible to create and maintain adequate concentrations of drugs. It has special meaning and impotence during the therapy antibiotic therapy of infectious and inflammatory processes. In this regard, the experimental study of pharmacological properties of drugs that enhance lymphatic drainage of tissues and at the same time promote the transport of antibiotics into the lymphatic system has natural interest. We studied the effect of unfractio

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Stogov, M. V., A. L. Shastov, E. A. Kireeva, and N. V. Tushina. "Release of antibiotics from the materials for postosteomyelitic bone defect filling." Genij Ortopedii 30, no. 6 (2024): 873–80. https://doi.org/10.18019/1028-4427-2024-30-6-873-880.

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Introduction The search for materials for bone defect filling that would provide a release of antibiotics in therapeutic levels over a long period is a pressing issue in the treatment of patients with osteomyelitis.The purpose of the work was to compare the kinetics of antibiotic release from materials based on polyurethane polymers for filling post-osteomyelitic bone defects.Materials and methods A comparative in vitro analysis of the kinetic release of cefotaxime, vancomycin, and meropenem from two materials was performed: one was based on polyurethane polymers (RK series) and the other on p

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Bhowmik, Anindita, Sunjukta Ahsan, Marufa Zerin Akhtar, and Md Shahidul Kabir. "Incidence of ?-lactamase producing Escherichia coli amongst clinical isolates in Dhaka, Bangladesh." Stamford Journal of Microbiology 5, no. 1 (2016): 18–21. http://dx.doi.org/10.3329/sjm.v5i1.26914.

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Escherichia coli is one of the most important clinical pathogens that demonstrate antibiotic resistance through their ? -lactamase activity. The present study reflected on the presence of ?-lactam antibiotic resistance in clinical samples. Antibiotic resistance patterns of 20 clinical isolates of Escherichia coli against ? -lactam antibiotics were investigated. These isolates were collected from a hospital in Dhaka city and MIC values were determined against Imipenem, Cefotaxime and Ceftriaxone. In case of Ceftriaxone the highest MIC was >4096 ?g/mL for 50% isolates with a minimum MIC of 1

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Mustafa, Lirim, Ilir Tolaj, Nehat Baftiu, and Hajrullah Fejza. "Use of antibiotics in COVID-19 ICU patients." Journal of Infection in Developing Countries 15, no. 04 (2021): 501–5. http://dx.doi.org/10.3855/jidc.14404.

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Introduction: The role of antibiotics in the treatment in COVID-19 cases has not yet been adequately defined, and no criteria have been established for antibiotic treatment, type and duration. Methodology: This paper reports the results of an observational study on the extent of antibiotic use in 52 randomly selected patients in the intensive care unit (ICU) at the University Hospital in Pristina, Kosovo with severe forms of COVID-19. Results: Antibiotics were prescribed in all the cases (52; 100%). Of the 52 patients, 1) 13 (25%) were given antibiotics before hospitalisation, 2) 4

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Hussein Jabbar Alhazza, Mohammed Sabar Al-Lami, Zuhair AlShaheen, and Ayad almakki. "Cefotaxime Eluting Niosomes as A Novel Approach to Potentiate the Antibacterial Activity." Journal of Pharmaceutical Negative Results 13, no. 4 (2022): 632–40. http://dx.doi.org/10.47750/pnr.2022.13.04.084.

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Multidrug resistance has resulted in hurtful infections on treatment with common antimicrobials and is associated with health threatening problems. Antibiotic abuse in health care systems contributes to global resistance. β-lactams are the predominantly used antibiotics, and the most often used is cefotaxime, therefore facing a resistance problem. Potent cephalosporin derivatives, β-lactamase inhibitors, prodrugs, and drug nano-carriers are approaches to cutback bacterial resistance. An example of a nanocarrier applied in field of antibacterial activity enhancement is niosomes. Niosomes are se

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Januari, Connie, Mirnawati Bachrum Sudarwanto, and Trioso Purnawarman. "Resistensi Antibiotik pada Escherichia coli yang Diisolasi dari Daging Ayam pada Pasar Tradisional di Kota Bogor (ANTIBIOTIC RESISTANCE IN ESCHERICHIA COLI ISOLATED FROM CHICKEN MEAT OF TRADITIONAL MARKETS IN THE CITY OF BOGOR)." Jurnal Veteriner 20, no. 1 (2019): 125. http://dx.doi.org/10.19087/jveteriner.2019.20.1.125.

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Antibiotic use in farm is spread widely to treat of poultry disease including therapy, supportive or preventive use and as afeed additive to improve chicken performance. The negative effects of antibiotic use can increase the level of bacterial resistance to antibiotics. This study aimed to investigate on antibiotic resistance in Escherichia coli isolated from chicken meat that were sold in Traditional Market of Bogor City. A total of 175 samples of chicken meat were taken by purposive sampling method, out of 175 found 50 positive samples of E. coli. The samples were subjected to E. coli exami

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Sinuraya, Rano K., Aida N. Aini, Cherry Rahayu, Nasrul Wathoni, and Rizky Abdulah. "The Effectiveness of Postoperative Antibiotics following Appendectomy in Pediatric Patients: A Cost Minimization Analysis." Open Public Health Journal 13, no. 1 (2020): 80–86. http://dx.doi.org/10.2174/1874944502013010080.

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Background: Appendicitis has a high occurrence and is frequently indicated in pediatric abdominal surgery. However, up to 33% of affected children may not present with distinct symptoms, and young children may be a typical or show delayed presentation of symptoms. Appendectomy is one of the most common emergent surgeries to treat appendicitis. After an appendectomy, prophylaxis antibiotics are required to abate infections at the location of surgery and have been shown to reduce postoperative surgical complications significantly. Objective: The purpose of this investigation was to determine the

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Grechishcheva, N. Yu, E. D. Dmitrieva, E. V. Akatova, V. I. Balaba, and V. L. Zavorotny. "Evaluation of the Detoxifying Ability of Humic Acids in Relation to Antibiotics." Ecology and Industry of Russia 27, no. 10 (2023): 30–35. http://dx.doi.org/10.18412/1816-0395-2023-10-30-35.

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The detoxifying ability of lowland peat humic acids at 10 to 110 mg/l concentration with respect to tetracycline, doxycycline, and cefotaxime was studied by bioanalysis on Escherichia coli K-802 strain. It was confirmed that, according to sensitivity to the presence of humic substances, the studied antibiotics were ranked as follows: cefotaxime > doxycycline > tetracycline. Humic acids were found to exhibit maximum detoxifying effect against cefotaxime in the entire concentration range. It was found that detoxification with respect to cefotaxime occurs mainly due to the binding of the an

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Amin, Muhammad, Eddy Bagus Wasito, and Erwin Astha Triyono. "Comparison between Exposure of Ciprofloxacin and Cefotaxime on Developing of Escherichia coli ESBL." Folia Medica Indonesiana 56, no. 2 (2020): 86. http://dx.doi.org/10.20473/fmi.v56i2.21203.

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This study aimed to compare ciprofloxacin and cefotaxime exposure to develop ESBL producing Escherichia coli (E. coli). A total of 16 isolates of cefotaxime sensitive E. coli and ciprofloxacin were exposed to ciprofloxacin and cefotaxime for 14 days using the Kirby-Bauer antibiotic disc diffusion method. Colonies that grew on the edge of the inhibiting zone were exposed each day by the same method. Furthermore, we observed the occurrence of resistance to cefotaxime as ESBL screening test. Isolates were resistant, the following day the ESBL was confirmed by the Modified Double Disk Sinergy Test

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García-Béjar, Beatriz, Izan García de Blas Martín, María Arévalo-Villena, and Ana Briones Pérez. "High Prevalence of Antibiotic-Resistant Escherichia coli Isolates from Retail Poultry Products in Spain." Animals 11, no. 11 (2021): 3197. http://dx.doi.org/10.3390/ani11113197.

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The prevalence of Escherichia coli was analysed in poultry products from different Spanish retailers and determined its antibiotic resistance capability by phenotypic (ampicillin, amoxicillin, chloramphenicol, gentamicin, imipenem, cefotaxime, tetracycline, ciprofloxacin, trimethoprim, and colistin) and genotypic assays. A total of 30 samples (hindquarters or livers) were collected from supermarkets and butchers. Enterobacteriaceae counts ranged between 3.2 and 6.5 log colony-forming units (CFU)/g, and the highest values were found in livers and in samples from supermarkets. E. coli was detect

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Kataeva, Natalia N., Natalia A. Naronova, Kristina O. Golitsyna, Nadezda A. Belokonova, and Ksenia E. Shulepova. "EVALUATION OF CEPHALOSPORIN’S LIPOPHILIC PROPERTIES." ChemChemTech 67, no. 7 (2024): 55–62. http://dx.doi.org/10.6060/ivkkt.20246707.7018.

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As a part of the study, a comparative analysis of different generations three representative’s lipophilic properties of cephalosporin antibiotics, namely cefazolin, cefotaxime and cefepime, was carried out. Lipophilicity is a very important physicochemical property of medicinal substances, since it determines their ability to pass through protective barriers, distribute, accumulate in tissues and body fluids, be broken down and excreted, which, in turn, affects the manifestation of antibacterial activity and the cytotoxic effect of antibiotics. During the experiment, a series of drugs aqueous

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Mineykina, Anna, Daria Shumilina, Ludmila Bondareva, Alexey Soldatenko, and Elena Domblides. "Effect of Beta-Lactam Antibiotics on Microspore Embryogenesis in Brassica Species." Plants 9, no. 4 (2020): 489. http://dx.doi.org/10.3390/plants9040489.

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Antibiotics are widely applied for plant cultivation in vitro to eliminate bacterial contamination. However, they can have both positive and negative effects on the cells of cultivated plants, and these effects largely depend on the type antibiotic used and its concentration. The objective of the present study was to estimate the effect of β-lactam antibiotics ampicillin (Amp) and cefotaxime (Cef) on microspore embryogenesis induction in vitro in the Brassica species. The performed experiments confirmed cefotaxime inhibits microspores in B. napus and B. oleracea, even in concentrations as low

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Bhutani, Natasha, Chithra Muraleedharan, Deepa Talreja, et al. "Occurrence of Multidrug Resistant Extended Spectrum Beta-Lactamase-Producing Bacteria on Iceberg Lettuce Retailed for Human Consumption." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/547547.

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Antibiotic resistance in bacteria is a global problem exacerbated by the dissemination of resistant bacteria via uncooked food, such as green leafy vegetables. New strains of bacteria are emerging on a daily basis with novel expanded antibiotic resistance profiles. In this pilot study, we examined the occurrence of antibiotic resistant bacteria against five classes of antibiotics on iceberg lettuce retailed in local convenience stores in Rochester, Michigan. In this study, 138 morphologically distinct bacterial colonies from 9 iceberg lettuce samples were randomly picked and tested for antibio

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Speekenbrink, A. B. J., S. R. Alcock, J. Forrester, and D. M. V. Parrott. "The effect of selective decontamination of the digestive tract with the addition of systemic cefotaxime on the aerobic faecal flora of mice." Epidemiology and Infection 98, no. 3 (1987): 385–95. http://dx.doi.org/10.1017/s0950268800062154.

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SUMMARYThe administration per-orally to mice of the non-absorbable antibiotics polymyxin E, tobramycin and amphotericin B resulted in the elimination of detectable aerobic gram-negative rods from the faecal flora without affecting the total viable aerobic count. The addition of parental cefotaxime to the regime caused a fall in the number of aerobic lactobacilli and an increase in the number of enterococci. The rise was associated with the translocation of viable enterococci to the mesenteric lymph nodes and the spleen. The changes induced by cefotaxime were reversed when the antibiotic was wi

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Sempere, Julio, Fernando González-Camacho, Mirian Domenech, et al. "A national longitudinal study evaluating the activity of cefditoren and other antibiotics against non-susceptible Streptococcus pneumoniae strains during the period 2004–20 in Spain." Journal of Antimicrobial Chemotherapy 77, no. 4 (2022): 1045–51. http://dx.doi.org/10.1093/jac/dkab482.

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Abstract Background Surveillance studies including antibiotic resistance and evolution of pneumococcal serotypes are critical to evaluate the susceptibility of commonly used antibiotics and the contribution of conjugate vaccines against resistant strains. Objectives To determine the susceptibility of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to penicillin to a panel of antibiotics during the period 2004–20 and characterize the impact of pneumococcal conjugate vaccines in the evolution of resistant serotypes. Methods We selected 3017 clinical isolates in order to

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Hile, Garrett B., Kaitlin L. Musick, Adam J. Dugan, Abby M. Bailey, and Gavin T. Howington. "Occurrence of Hyperbilirubinemia in Neonates Given a Short-term Course of Ceftriaxone versus Cefotaxime for Sepsis." Journal of Pediatric Pharmacology and Therapeutics 26, no. 1 (2021): 99–103. http://dx.doi.org/10.5863/1551-6776-26.1.99.

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OBJECTIVE Ceftriaxone and cefotaxime are appealing options for the treatment of neonatal infections. Guidelines recommend cefotaxime as the cephalosporin of choice in neonates because of ceftriaxone's potential to cause hyperbilirubinemia. Unfortunately, due to cefotaxime discontinuation, providers must choose between alternative antibiotics. Clinicians at our institution adopted a protocol allowing for the utilization of cefepime and ceftriaxone for the management of neonatal sepsis. The objective of this study was to compare the incidence of hyperbilirubinemia between ceftriaxone and cefotax

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Agnes, Agatha, Gayatri Citraningtyas, and Sri Sudewi. "ANALISIS EFEKTIVITAS BIAYA PADA PASIEN ANAK DEMAM TIFOID DI RUMAH SAKIT BHAYANGKARA MANADO." PHARMACON 8, no. 2 (2019): 335. http://dx.doi.org/10.35799/pha.8.2019.29299.

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ABSTRACT Typhoid fever is an endemic disease which it incidence rate is still high in Indonesian. Administering antibiotic therapy can do treatment of typhoid fever. This study was conducted since there are several pediatric patients diagnosed with typhoid fever but have different antibiotic therapies, namely cefotaxime and ceftriaxone therapy, so it is necessary to do calculations to determine the comparison and determine which treatment is more efficient in cost and effectiveness. The method used in this study is CEA (Cost-Effectiveness Analysis) with the design of retrieving medical record

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Diany Astuti and Yuli Nurhayati. "EVALUASI KUALITATIF PENGGUNAAN ANTIBIOTIK PADA PASIEN ANAK DENGAN METODE GYSSENS DI RSUD KARAWANG." Pharma Xplore : Jurnal Ilmiah Farmasi 4, no. 1 (2019): 297–302. http://dx.doi.org/10.36805/farmasi.v4i1.620.

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ABSTRAK Peresepan antibiotik untuk pasien anak-anak paling banyak digunakan dalam terapi. Penggunaan Antibiotik untuk anak-anak harus diawasi dan dikendalikan karena penggunaan antibiotik yang tidak terkontrol dan tidak tepat dapat berdampak pada kegagalan efek terapi yang diharapkan dan kemungkinan dapat meyebabkan resistensi antimikroba. Pemakaian antibiotik harus dianalisis untuk mengendalikan resistensi antibiotik. Tujuan penelitian ini untuk menilai rasionalitas terapi antibiotik pada pasien anak. Penelitian ini merupakan analisis deskriptif retrospektif dengan pengambilan data purp

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