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Dissertations / Theses on the topic 'Antibiotics'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Dodgen, Taylor L. "Escherichia coli and Antibiotic Resistance to Tetracycline Antibiotics." Lynchburg, Va. : Liberty University, 2008. http://digitalcommons.liberty.edu.

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2

Lee, Henry Hung-Yi. "A systems approach to the evolution of antibiotic resistance." Thesis, Boston University, 2012. https://hdl.handle.net/2144/31582.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Antibiotic-resistant bacterial strains continually arise and their increasing prevalence poses significant clinical and societal challenges. Functional analyses of resistant mutants and the study of general s

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3

Meng, Li. "Development of one-step strip test for rapid detection of antibiotic residues in animal body fluid and food animal products /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?BIEN%202006%20MENG.

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4

Millar, Michael. "Antibiotics and antibiotic resistance : what do we owe to each other?" Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/4780/.

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There is a tension between the need to use antibiotics to prevent adverse outcomes from infection, and a consequence of their use, which is antibiotic (treatment) resistant infection. Actions taken to control the spread of antibiotic resistant microbes, and constraints on the use of antibiotics both give rise to ethical tensions. I consider the evaluative framework and the principles that might be used to decide a just distribution of burdens and benefits associated with the use of antibiotics. Nussbaum specifies a list of capabilities. A minimum sufficiency of each capability is required for

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5

Wolken, Kathryn, and Velliyur Viswesh. "The Appropriateness of Antibiotic Therapy in Patients Initiated on Meropenem in a University-Affiliated Hospital." The University of Arizona, 2011. http://hdl.handle.net/10150/623557.

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Class of 2011 Abstract<br>OBJECTIVES: To determine the appropriateness of antimicrobial therapy in patients initiated on empiric meropenem therapy. METHODS: Adult patients prescribed empiric meropenem therapy between January 1, 2010 and March 31, 2010 at a tertiary care, academic medical center were included. Data collected included site of infection, culture and susceptibility data, risk factors for multi-drug resistant organisms, and changes in antimicrobial therapy during the first seven days after meropenem therapy was initiated. Demographic variables included age, sex, weight, and race.

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6

Silva, Niléia Cristina da [UNESP]. "Remoção de antibióticos da água por meio do processo de adsorção em carvão ativado." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/97882.

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Made available in DSpace on 2014-06-11T19:29:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-02-28Bitstream added on 2014-06-13T19:58:49Z : No. of bitstreams: 1 silva_nc_me_ilha.pdf: 1099312 bytes, checksum: 9c9ba0080ad7da78d422c26ceed640a6 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Este trabalho trata da remoção de fármacos da água por meio do processo de adsorção, utili- zando como adsorvente o carvão ativado obtido da casca de coco da baía. Os fármacos utili- zados foram os antibióticos Amoxicilina, Ampicilina, Cefalexina e Ciprofloxacina. O

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7

Batista, Ana Paula dos Santos [UNESP]. "Degradação de antibióticos sulfonamidas por processo foto-Feton: identificação de intermediários." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/105698.

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Made available in DSpace on 2014-06-11T19:35:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-04-20Bitstream added on 2014-06-13T21:07:10Z : No. of bitstreams: 1 batista_aps_dr_araiq.pdf: 2244640 bytes, checksum: a5ffee8c291916749f781e502663553e (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A degradação foto-Fenton dos antibióticos sulfonamidas sulfadiazina (SDZ) e sulfatiazol (STZ) mediados por Fe(III)-oxalato foi estudada nesse trabalho. A influência da complexação de íons ferro, a concentração de H2O2 e o pH na velocidade inicial de degradação do

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8

Fisher, Morgane, (Dennison) Jaime Thomas, and Danielle Weimann. "Effects of an Educational Intervention on Parental Knowledge Regarding Antibiotic Resistance." The University of Arizona, 2008. http://hdl.handle.net/10150/624276.

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Class of 2008 Abstract<br>Objectives: To evaluate changes in parental knowledge regarding antibiotic use and antibiotic resistance with an educational intervention given at elementary school parent-teacher association (PTA) meetings. Methods: This was an analytical pre-test/post-test study of an educational intervention given at two elementary schools in the Phoenix metro area. The primary dependent variable was a knowledge measure, calculated as a total score. The changes between the pre- and post-test total score means were compared using a dependent t-test. The a-priori alpha level used wa

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9

Starosta, Agata Lucyna. "Antibiotics and translation." Diss., Ludwig-Maximilians-Universität München, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-170210.

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10

Tangeman, Lorraine Susan. "Can Antibiotics From Recently Discovered Marine Actinobacteria Slow the Tide of Antibiotic Resistance?" Wright State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=wright1377522942.

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11

Hedin, Matthew Lowell. "The Effects of dairy cattle antibiotics on soil microbial community cycling and antibiotic resistance." Thesis, Virginia Tech, 2018. http://hdl.handle.net/10919/83227.

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Antibiotic use in agricultural ecosystems has the potential to increase resistance to antibiotics in soil microbial communities since 40-95% of an antibiotic dose administered to livestock is excreted intact or as metabolites. Exposure to antibiotics is also known to alter microbial community composition, biomass, and physiology, but the potential influences of antibiotic residues on the essential ecosystem processes that microbes regulate, e.g., carbon and nitrogen cycling are not well understood. I investigated the effects of antibiotic residues associated with dairy cattle operations on soi

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12

DeSilva, Malini. "Efficacy of Print Media Risk Communication About Antibiotic Resistance." Thesis, Boston College, 2003. http://hdl.handle.net/2345/427.

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Thesis advisor: Roche P. John<br>The growing threat of antibiotic resistance makes it extremely important that citizens be informed about the risks posed by antibiotic-resistant bacteria, and measures with which they can reduce these risks. The print media are major sources of such information for members of the public. In the present study, articles from major newspapers in the United States and Canada appearing between 1998 and 2002 were surveyed to determine the extent to which mention was made of antibiotic resistance and the risks associated with antibiotic resistance, the contextual prec

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13

Wallace, Jeremy Iain. "Hyperinducible Î²-lactamase expression in gram-negative bacteria." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295568.

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14

Fermér, Elin. "Selection for Antibiotic Resistance Below Minimal inhibitory concentration in Biofilm." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-409806.

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Antibiotics are today one of the most important cornerstones in modern healthcare when it comes to treating bacterial infections. It is an asset human kind have been leaning on for the last century, but excessive and widespread misuse of antibiotics have left deep scars in the form of multi resistant pathogenic strains of bacteria that we soon will not be able to treat. A lot of research have been invested in understanding the mechanisms and spread of resistance within bacteria living in planktonic form, overlooking the fact that there are more lifestyles that causes problems. In this study, f

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15

Santiago, Marina Joy. "New Genomics Tools and Strategies for Studying Antibiotics and Antibiotic-Resistance in Staphylococcus Aureus." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493460.

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Staphylococcus aureus is a gram positive coccoid pathogen that causes intractable infections in hospitals and communities around the world, and tens of thousands of people die of these infections every year. In order to combat these antibiotic-resistant infections, we need to better understand the genes involved in resistance to the cell stress caused by antibiotic treatment, which will enable the discovery of new antimicrobials and the development of novel therapeutic strategies. We chose to use an approach to this problem that utilizes a new phage-based high frequency of transposition system

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16

Caproni, Lisa J. "Antibiotics and Clostridium difficile." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/24132.

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The aims of this thesis were to investigate the antibiotic susceptibility patterns of <i>C. difficile</i> with relation to the S-type of the isolates over a period of 18 months. Detailed growth curves were performed on strains NCTC 11223, the sequenced strain 630 and an endemic isolate 338a. Toxin A was shown to be produced upon entry to stationary phase in agreement with other studies. OD<sub>600</sub> was found to be a good predictor of growth phase and allowed this measurement to be used for subsequent experiments. MICs were performed on 186 random isolates of <i>C. difficile</i> collected

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17

Buckley, George Martin. "Siderphones as potential antibiotics." Thesis, University of Nottingham, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335854.

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18

Zhu, Hongkun. "Studies of Aminoglycoside Antibiotics." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1462802472.

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19

Cho, Hyeongjin. "Studies in antibiotics biosynthesis /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487676847114716.

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20

Al-Lawati, Nabila J. M. "Analysis of complex antibiotics." Thesis, University of Brighton, 2012. https://research.brighton.ac.uk/en/studentTheses/6af329d7-a44a-4c05-bd26-5664eddcbb1c.

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The emergence of multidrug resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii has been recognized worldwide and some clinical isolates of these bacteria are now resistant to most of the antibiotics currently available. Unfortunately, there are at present not enough new antimicrobial drugs being produced by the pharmaceutical industry to keep pace with the continuing development of antibiotic resistance. Colistin is an old antibiotic and in the form of colistin methanesulphonate sodium (CMS) has re-emerged as a major treatment for burn patients colonised

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21

Wei, Xi. "Effects of residual veterinary antibiotics on soil enzyme activity and plant growth." HKBU Institutional Repository, 2007. http://repository.hkbu.edu.hk/etd_ra/830.

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22

Preece, Lewis. "Studies toward a total synthesis of Lactonamycin." Thesis, University of Sussex, 2012. http://sro.sussex.ac.uk/id/eprint/39607/.

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Work was undertaken towards the synthesis of the promising antibiotic lactonamycin (iii). Following the work of Parsons et al. it was proposed that cyclisation of the ene-diyne (i) would give access to advanced pentacyclic intermediate (ii) and that from this a total synthesis of lactonamycin would be achieved (scheme I). Scheme I : Proposed Parsons, Board, Waters cyclisation to form the pentacycle (iii)(For image refer to pdf). A synthesis towards the cyclisation precursor (i) was carried out and a route to the key tetrasubstituted phthalide (v) established. Further chemistry was proposed to

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23

Bronson-Lowe, Daniel. "Impact of an Environmental Hygiene Intervention on Illness and Microbial Levels in Child Care Centers." Diss., The University of Arizona, 2006. http://hdl.handle.net/10150/195257.

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Pathogens on surfaces in child care centers can contribute to illness among attendees and may thereby contribute to medical visits as well. This intervention study was conducted to assess the effect of using specific sanitizing products and cleaning protocols in child care centers on the incidences of lower respiratory infections, diarrheal illness, antibiotic use, and medical visits among children attending the centers and on the levels and antibiotic resistance of indicator bacteria in those centers. During the ten-week study period, children from twelve centers were observed. Six of the c

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24

Giraldo, Gómez Jennifer. "Transfer of antibiotics from goat's milk to cheese and whey." Doctoral thesis, Universitat Politècnica de València, 2020. http://hdl.handle.net/10251/155899.

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[ES] La presencia de residuos de antibióticos en la leche y los productos derivados representa un riesgo para los consumidores. Límites Máximos de Residuos (LMRs) no se han fijado para los productos lácteos y la transferencia de antibióticos de la leche a la cuajada y al lactosuero durante el proceso de elaboración del queso apenas ha sido estudiada. El objetivo de esta tesis fue evaluar la transferencia de antibióticos de la leche al queso y lactosuero, así como la validación de las características de varios métodos de cribado para la detección de antibióticos en muestras de suero de leche.

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25

Messer, Janet Mariam. "Bacterial resistance ot glycopeptide antibiotics." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239488.

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26

Cuthbert, B. K. "Analogues of beta-lactam antibiotics." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370245.

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27

Harvey, B. M. "The biosynthesis of polyether antibiotics." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603821.

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This research aimed to delineate the final stages of polyether biosynthesis, using the monensin pathway as a model system. The metabolites produced by mutants in which the gene encoding the putative epoxidase MonCI (monCI) along with the proposed isomerase genes <i>monBII </i>and <i>monBII </i>(BHΔCIBIBII) were disrupted were found to be (stereo)chemically identical to those produced by a strain deficient in monCI only (ABΔCI), suggesting that MonBI and MonBII do not play a role in double bond isomerisation. In agreement with this, site-directed mutagenesis of a residue in MonBI previously imp

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28

Doherty, Annette Marian. "Synthetic approaches to ionophore antibiotics." Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37676.

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29

Goldberg, Manijeh Nazari. "Best antibiotics for buccal delivery." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/68466.

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Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 64-66).<br>The purpose of the research was to identify the clinical and commercial benefits of switching from intravenous (IV) to buccal delivery of antibiotics. then, the research continued to select 3-5 antibiotics that best met the buccal delivery and market requirements. Methods: The research began with the hypothesis that some injectable antibiotics are good candidates for buccal delivery even with the limitations imposed by the b

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30

Maplestone, Rachael Anne. "Structural studies on glycopeptide antibiotics." Thesis, University of Cambridge, 1992. https://www.repository.cam.ac.uk/handle/1810/272376.

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31

Varlakova, A., Нiна Володимирiвна Мальована, Нина Владимировна Малеванная, and Nina Volodymyrivna Malovana. "Bacteriophages as alternatives to antibiotics." Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/77972.

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The history of the discovery of bacteriophages began almost a century ago. In spite of the appearance of antibiotics, bacteriophages are still extremely promising. Bacterial infections are an urgent public health problem, due to the increasing of antibiotic resistance and negative health consequences. Thus, phages are currently considered as an alternative treatment, which are going to replace antibiotics.

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32

Lamb, Sherry S. Wright Gerard D. "Glycopeptide antibiotics: Sulfation and modification." *McMaster only, 2007.

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33

McDonald, Matthew G. "Biosynthetic studies on phenazine antibiotics /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/8699.

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34

Liang, Yi. "Carbohydrate Derivatives in Antibiotics Research." DigitalCommons@USU, 2009. https://digitalcommons.usu.edu/etd/298.

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In this study, we investigated the potential applications of carbohydrates in the development of new antibiotics. To tackle the problem of multidrug-resistant variants of M. tuberculosis (MDR-TB), we investigated the biosynthesis pathways of trehalose, which has contributed to significant drug resistance. Some new methods were developed for the synthesis of potential inhibitors (6-azido-trehalose and 6,6'-diazido-trehalose) that have been designed to imitate the intermediate molecule (trehalose 6-phosphate, TPP) of OtsA-OtsB pathway. At the same time, some new antibacterial agents based on tre

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35

Wongdontree, Paprapach. "Staphylococcus aureus Adaptation to FASII-Targeted Antibiotics in Host Environments and Strategies to Potentiate Antibiotic Activities." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASB088.

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Staphylococcus aureus est un pathogène opportuniste responsable d’infections difficiles à traiter dues à l’inefficacité des antibiotiques actuels. En 2019, cette bactérie a causé le taux de mortalité mondial le plus élevé. La nécessité de recherche de nouveaux antibiotiques a permis de développer de nouvelles molécules inhibant la synthèse des acides gras de type II (FASII). Cependant, ces molécules anti-FASII présentent une faiblesse : S. aureus et les pathogènes Firmicutes sont capables de contourner l’inhibition de FASII par incorporation d’acides gras environnementaux présents dans l’hôte

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36

Ramstedt, Rebecka, and Susanna Ahnlund. "Health in the headlines : How two Indian newspapers treat antibiotic resistance." Thesis, Södertörns högskola, Institutionen för samhällsvetenskaper, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-19510.

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In India, there is no regulation of antibiotics and allegedly the use has doubled since 2006. Indiscriminate use of antibiotics gives rise to development of resistant bacteria. The media has, according to the theories used in this study, a responsibility to educate and empower the people to make personal judgments about health risks. This study focuses on the extent to which two of the largest English-language newspapers in India, the Hindu and Times of India, report on antibiotic resistance; and also, how the journalists and editors on these newspapers look upon their profession and responsib

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37

Bergfeldt, Vendela. "Microbes that never sleep : A multidisciplinary study of the antibiotic resistance management in Sweden." Thesis, Södertörns högskola, Institutionen för naturvetenskap, miljö och teknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-30623.

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The hypotheses of this study are that reduction and rational usage of antibiotics reduces development of antibiotic resistance. In Sweden, the trends do not follow this pattern. Despite a decrease in prescriptions of antibiotics, there is an increase in the number of patients infected with Methicillin-resistant Staphylococcus Aureus (MRSA), Extended Spectrum Beta-Lactamases (ESBL) and ESBL selecting for carbapenem-resistance (ESBLCARBA). This study aims to study factors affecting antibiotic resistance management. An additional aim is to use a multidisciplinary approach for a subject that has m

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38

Norgren, Benjamin. "What role does aquaculture play in the global rise of antibiotic-resistant bacteria?" Thesis, Stockholms universitet, Institutionen för ekologi, miljö och botanik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-182602.

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In a world where the human population is increasing, new innovations to produce enough food are required. Aquaculture’s part of the global animal protein production has increased in recent years and could be a possible solution. However, if aquaculture is poorly managed, it can result in negative consequences and one such consequence is the development of antibiotic resistance. In this review, I examine how aquaculture affect antibiotic resistance by studying what the literature says on accumulation of antibiotics in different organisms and sediment, if antibiotics can be transferred to humans

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39

Skinner, Michael Fredrick. "Biopharmaceutics and pharmacokinetics of the macrolide antibiotic Josamycin." Thesis, Rhodes University, 1992. http://hdl.handle.net/10962/d1003269.

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The investigations detailed herein have been conducted to address various aspects of the biopharmaceutics and pharmacokinetics of josamycin which to-date, have received little or no attention in the literature. Areas of investigation have included the selective determination of josamycin in serum and urine samples, the stability of josamycin in stored biological samples, intrinsic dissolution rates, solubility, acid and alkali stability and bioavailability and pharmacokinetics after dosing with a solution, powder and tablets. High performance liquid chromatography (HPLC) was used as the main a

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40

Larsson, Mattias. "Antibiotic use and resistance : assessing and improving utilisation and provision of antibiotics and other drugs in Vietnam /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-630-8/.

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41

Lindberg, Richard. "Determination of Antibiotics in the Swedish Environment with Emphasis on Sewage Treatment Plants." Doctoral thesis, Umeå : Univ, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-745.

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42

Osman, Hasnah, and n/a. "Synthetic approaches to the angucycline antibiotics." University of Otago. Department of Chemistry, 2005. http://adt.otago.ac.nz./public/adt-NZDU20070426.160307.

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The stereoselective synthesis of urdamycinone B (17) was achieved in a 21% overall yield from C-glycosyl-naphthoquinone 197. The key reaction was the Diels-Alder cycloaddition reaction of 197 and siloxydiene (�)-117 promoted by a chiral Lewis acid derived from (S)-3,3�-diphenyl-1,1�-binaphthalene-2,2�-diol (291), BH₃.THF and acetic acid. An effective kinetic resolution of (�)-117 occurred. Four cycloadducts 199a-d were formed in a ratio between 84:8:2:6 and 70:9:2:19. Aromatisation of the mixture by treatment with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) gave 200a and 200b in 4:1 ratio. A sequ

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43

Pohanka, Anton. "Antifungal antibiotics from potential biocontrol microorganisms /." Uppsala : Department of Chemistry, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200647.pdf.

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44

Lovmar, Martin. "Macrolide Antibiotics in Bacterial Protein Synthesis." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6009.

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45

Wohlrab, Aaron M. "The total synthesis of depsipeptide antibiotics." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3284214.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed January 14, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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46

Parisi, M. F. "Synthetic and biosynthetic studies on antibiotics." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371556.

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47

Williams, A. C. "An approach to the lankacidin antibiotics." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376963.

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48

Churcher, Ian. "Synthesis of potential pyrazolidinone-containing antibiotics." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318637.

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49

Christofilogiannis, Panagiotis. "Use of antibiotics in Greek mariculture." Thesis, University of Stirling, 2002. http://hdl.handle.net/1893/3250.

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Bacteriological survey of the fish pathogens in Greek mariculture between 1994- 1997 was followed by analysis of prevalence in sea bass, sea bream, sharpsnout bream and common Dentex and discussion of the impact of various fish pathogens. In addition antibiotic resistance profiles and frequencies were studied using quantitative antibiogram and MIC analysis for the two most commonly used antibiotics Oxolinic acid and Oxytetracycline and clinically relevant MIC breakpoints were extrapolated for different fish species and main fish pathogens. The kinetics of the above antimicrobials were analysed

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50

Reza, Khalid. "Synthetic approaches to the benzanthraquinone antibiotics." Thesis, University of Salford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258376.

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