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Journal articles on the topic 'Antibiotics'

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1

Bagga, S., and N. Patel. "An audit to evaluate the prescribing of antibiotics for acne against NICE guidelines in a digital setting." International Journal of Pharmacy Practice 32, Supplement_2 (2024): ii18—ii19. http://dx.doi.org/10.1093/ijpp/riae058.021.

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Abstract Introduction According to NICE guidelines, individuals with moderate to severe acne may be recommended a fixed combination of topical treatment along with either oral lymecycline or doxycycline for a 12-week regimen1. If improvement is observed in these patients, continuation of the oral antibiotic and non-antibiotic-topical treatment for an additional 12 weeks is advised. It's important to adhere to these guidelines and avoid prescribing monotherapy topical antibiotics, monotherapy oral antibiotics, or the combination of topical antibiotics with oral antibiotics2. This audit aims to
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Hochvaldová, Lucie, Renata Večeřová, Milan Kolář, et al. "Antibacterial nanomaterials: Upcoming hope to overcome antibiotic resistance crisis." Nanotechnology Reviews 11, no. 1 (2022): 1115–42. http://dx.doi.org/10.1515/ntrev-2022-0059.

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Abstract When combined with nanomaterials, antibiotics show antibacterial activity against susceptible and resistant bacterial strains at significantly lower concentrations. Unfortunately, to date, no research study has examined the effect of the antibiotic mode of action and mechanism of bacterial resistance on the effectiveness of combined antibacterial treatment with nanomaterials. Therefore, in this review, we performed a thorough analysis and critical evaluation of previously published data related to the combined antibacterial effect of antibiotics with nanostructured materials with a ta
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Hovhannisyan, V., and S. Altunyan. "DETERMINATION OF ANTIBIOTIC RESISTANCE IN CATTLE." Znanstvena misel journal, no. 73 (December 26, 2022): 6–8. https://doi.org/10.5281/zenodo.7483265.

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Antibiotic resistance in various living animals as well as human organisms is considered one of the problems of our time. Antibiotics used for curative-prophylactic purposes in animals, as well as various feed additives and growth promoters, can cause resistance to the antibiotic. We have investigated biological samples of 50 cattles, and in 35 samples out of them were detected E-coli and in 9 cases Salmonella spp.es were found. Belonging to the group of enterobacter: Salmonella spp. and E-coli spp. were studied to determine their response to 16 antibiotics. According to the results of the res
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Jikia, D., T. Chkhikvadze, I. Mgaloblishvili та K. Gzobava. "ანტიბიოტიკები: რაციონალური გამოყენების პრინციპები (ქირურგიული ანტიბიოტიკოპროფილაქტიკის საკითხები)". Guram Tatishvili Bulletin of Georgia Surgery, № 09 (25 грудня 2021): 36–43. http://dx.doi.org/10.48412/gtbgs.2021.09.36-43.

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The article discusses the key issues and definitions of antibacterial therapy. The main properties and mechanisms of action of antibiotics are described. Attention is drawn to the postulates of the use of antibiotics in clinical practice and the principles of modern rational antibacterial therapy. In the form of tables, the main approaches to surgical "antibacterial therapy" in the pre- and postoperative period, in different areas of surgery, are presented separately. ნაშრომში განხილულია ანტიბიოტიკოთერაპიის საკვანძო საკითხები და დეფინიციები. აღწერილია ანტიბიოტიკების ძირითადი თვისებები და მოქმე
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Sembiring, Pintata, Masria Sianipar, Sri Sudewi Pratiwi Sitio, Yunita Syahputri Damanik, and Efrata Sembiring. "EDUKASI PENGGUNAAN ANTIBIOTIK PADA SISWA/SISWI SMA NEGERI 1 STM HILIR, JLN. PENDIDIKAN DUSUN I TALUN KENAS, KEC. SINEMBAH TANJUNG MUDA HILIR, KAB. DELI SERDANG, SUMATERA UTARA." Jurnal Pengabdian Masyarakat Putri Hijau 3, no. 3 (2023): 29–31. http://dx.doi.org/10.36656/jpmph.v3i3.1342.

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Overuse of antibiotics has the potentiall for irrational use. This is one of the factorss that cause resistances. WHO in the field of antimicrobial resistance:According to the Global Surveillance Report, Southeast Asia has the highest level of antimicrobial resistance in the world, especially against methicillin-resistant Staphylococcus aureus (Ministry of Health, 2015). Results of the AMRIN (Antimicrobial Resistance in Indonesia) study conducted from 2000 to 2005 showed that approximately 43% of E. coli are resistant to various types of antibiotics, including:
 ampicillin (34%), co-trimo
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Sterling, Stephanie, Arnold Decano, and Evelyn Fabian. "1098. Perioperative Antibiotic Stewardship for Interventional Radiology Cases Improves Antibiotic Decision-Making." Open Forum Infectious Diseases 6, Supplement_2 (2019): S390. http://dx.doi.org/10.1093/ofid/ofz360.962.

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Abstract Background Appropriate periprocedural antibiotic prophylaxis is critical to optimize in order to reduce excessive antibiotics exposure for patients and to minimize the risk for procedure-related infection. Wrong antibiotic or excess antibiotics increase the risk for development of antimicrobial resistance, Clostridium difficile infection, adverse side effects. Incorrect or missed antibiotic can put the patient at risk for an infection. Methods Interventions included education of vascular and interventional radiology (IR) consult RN and physicians regarding updated institutional antimi
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7

Patel, Payal K., Naoyuki Satoh, Masashi Narita, et al. "172. Inpatient Antibiotic Prescribing Patterns Using the WHO Access Watch and Reserve (AWaRe) Classification in Okinawa, Japan: A Point Prevalence Survey." Open Forum Infectious Diseases 8, Supplement_1 (2021): S195—S196. http://dx.doi.org/10.1093/ofid/ofab466.374.

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Abstract Background Few studies have been done on inpatient antibiotic use in Japan and antibiotic stewardship programs with dedicated full-time equivalents are rare. We sought to better understand inpatient antibiotic use in Okinawa, Japan. We applied the World Health Organization (WHO) Access, Watch and Reserve (AWaRe) Classification to compare our findings to international literature. Access antibiotics are common front-line antibiotics, Watch antibiotics are high-priority antibiotics with toxicity or resistance concerns, and Reserve antibiotics are last-line treatments for multi-drug resis
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Miller, Benjamin, Kathryn Carson, Sujay Pathak, and Sara C. Keller. "1978. Statements about Antibiotic Side-Effects and Patient Desire for Unnecessary Antibiotics." Open Forum Infectious Diseases 6, Supplement_2 (2019): S662. http://dx.doi.org/10.1093/ofid/ofz360.1658.

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Abstract Background Antibiotic resistance is a global health emergency fueled in part by non-indicated use of antibiotics. Current public education campaigns primarily focus on the risks of global antibiotic resistance or society-wide adverse impacts of antibiotic misuse. There has been little research into what messages have the greatest impact on patient requests for non-indicated antibiotics. Methods We administered a survey at a primary care clinic in August 2018. Participants rated 18 statements about potential harm from antibiotics on how that statement changed their likelihood to reques
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Dian, Andriani Ratna Dewi, Arkania Nabila, Made Wiliantari Ni, et al. "Alternative Antibiotics Therapy for Drug-resistant Gonorrhea: A Literature Review." Journal of Health and Medical Sciences 6, no. 3 (2023): 32–51. https://doi.org/10.31014/aior.1994.06.03.275.

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Background: The management and control of gonorrhea are hampered by the widespread resistance to the diverse strains of Neisseria gonorrhea. Resistance to sulfonamides, penicillins, tetracyclines, macrolides, fluoroquinolones, and early cephalosporins has emerged rapidly. Purpose: This systematic review aimed to assess what antibiotics can be used as an alternative therapy for gonorrhea infections that are resistant to antibiotics. Methods: The study was conducted using the Web of Science, PubMed, Embase, and CENTRAL databases, following the Preferred Reporting Items for Systematic Reviews and
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Ahmed, Iftekhar, Md Bodiuzzaman Rabbi, Marufa Rahman, et al. "Knowledge of antibiotics and antibiotic usage behavior among the people of Dhaka, Bangladesh." Asian Journal of Medical and Biological Research 6, no. 3 (2020): 519–24. http://dx.doi.org/10.3329/ajmbr.v6i3.49803.

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Bangladesh is a developing country with a very high prevalence of antibiotic resistance where irrational use of antibiotics is very common. This cross-sectional survey was conducted to assess the knowledge of antibiotics and antibiotic usage behavior (Antibiotic use, self-medication, adherence to therapy) among the people of Bangladesh. The association between participants’ knowledge of antibiotics and their antibiotic usage behavior was also analyzed. A cross-sectional survey based on a structured questionnaire was conducted in the Dhaka district. The questionnaire included questions about de
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Dantuluri, Keerti L., Kemberlee R. Bonnet, David G. Schlundt, et al. "Antibiotic perceptions, adherence, and disposal practices among parents of pediatric patients." PLOS ONE 18, no. 2 (2023): e0281660. http://dx.doi.org/10.1371/journal.pone.0281660.

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Antibiotics are frequently prescribed for children in the outpatient setting. Although sometimes necessary, antibiotic use is associated with important downstream effects including the development of antimicrobial resistance among human and environmental microorganisms. Current outpatient stewardship efforts focus on guiding appropriate antibiotic prescribing practices among providers, but little is known about parents’ understanding of antibiotics and appropriate disposal of leftover antibiotics. To help bridge this gap, we conducted a qualitative study to assess parental understanding of the
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Kong, Lai San, Farida Islahudin, Leelavathi Muthupalaniappen, and Wei Wen Chong. "Knowledge and Expectations on Antibiotic Use among Older Adults in Malaysia: A Cross-Sectional Survey." Geriatrics 4, no. 4 (2019): 61. http://dx.doi.org/10.3390/geriatrics4040061.

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Antibiotics are commonly prescribed among older adults, and inappropriate use of antibiotics has been noted. However, there is limited information about their knowledge and expectations for antibiotics. This study aimed to assess older adults’ knowledge of antibiotic use and resistance, their expectations for antibiotics and the relationship between knowledge, expectation and inappropriate practices related to antibiotic use. A cross-sectional survey involving respondents aged 60 years and above was conducted, using a validated questionnaire. A lack of knowledge about the role of antibiotics w
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Danielewski, Maciej, Dorota Ksiądzyna, and Adam Szeląg. "NON-ANTIBIOTIC USE OF ANTIBIOTICS." Postępy Mikrobiologii - Advancements of Microbiology 57, no. 4 (2019): 301–12. http://dx.doi.org/10.21307/pm-2018.57.4.301.

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14

Simonson, William. "Antibiotic stewardship: Revisiting quinolone antibiotics." Geriatric Nursing 38, no. 2 (2017): 152–53. http://dx.doi.org/10.1016/j.gerinurse.2017.03.008.

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15

Heinemann, Jack A. "How antibiotics cause antibiotic resistance." Drug Discovery Today 4, no. 2 (1999): 72–79. http://dx.doi.org/10.1016/s1359-6446(98)01294-x.

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Heinemann, Jack A., Robert G. Ankenbauer, and Carlos F. Amábile-Cuevas. "Do antibiotics maintain antibiotic resistance?" Drug Discovery Today 5, no. 5 (2000): 195–204. http://dx.doi.org/10.1016/s1359-6446(00)01483-5.

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17

Bianco, Aida, Francesca Licata, Rossella Zucco, Rosa Papadopoli, and Maria Pavia. "Knowledge and practices regarding antibiotics use." Evolution, Medicine, and Public Health 2020, no. 1 (2020): 129–38. http://dx.doi.org/10.1093/emph/eoaa028.

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Abstract Background and objectives This study aimed to assess the knowledge on antibiotics and antimicrobial resistance (AMR) and the antibiotic use among the general public in Southern Italy and to analyze whether sociodemographic characteristics could be associated with poor knowledge and improper practices. Methodology From March to November 2019, a face-to-face interview was conducted with adult subjects attending the waiting room of 27 randomly selected general practitioners (GPs) in Southern Italy. The questionnaire covered sociodemographic characteristics, knowledge on antibiotics and A
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Hama, Kazhal Hassan, Ismail Bilal Ismail, Aza Bahadeen Taha, and Sadiya Abdullah Mawlud. "Assessment of Antibiotics Misuse among People in Erbil City." Kufa Journal for Nursing Sciences 4, no. 3 (2015): 25–35. http://dx.doi.org/10.36321/kjns.vi20143.2772.

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Background: Antibiotics are only useful for treating bacterial infections. Inadequate use of antibiotics includes overuse, inappropriate type, dose, duration and/or frequency of administration had been a major problem. Antibiotic use has been identified as a major contributor to the development and spread of antibiotic resistance. Objectives: Assessment self-medication and inappropriate of antibiotics were used among people in Erbil city. To find out the associations between the antibiotic use and knowledge related antibiotic consumption. Methodology: The study was used a cross-sectional study
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Dr., Musa Shuaibu, Aliyu-Zubair Ramatu Dr, and Haliru Lawal Dr. "Point Prevalence Study of Antibiotics use in Paediatric Wards of a Tertiary Health Facility in Kaduna Nigeria." International Journal of Innovative Science and Research Technology 8, no. 1 (2023): 555–62. https://doi.org/10.5281/zenodo.7576501.

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Children often receive prescriptions for antibiotics due to their relatively high rates of infection. Overuse or inappropriate antibiotics prescription can contribute to the development of drug resistance, longer hospital stays, and higher healthcare costs. Proper regulation of antibiotic use is necessary to protect the effectiveness of these limited treatment options. This study was conducted to determine prevalence of antibiotics use to establish baseline data for audit, formulate guidelines, support prescribing initiatives and ultimately improve quality of antibiotics use. Treatment charts
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Xiao, Gang, Jiyun Li, and Zhiliang Sun. "The Combination of Antibiotic and Non-Antibiotic Compounds Improves Antibiotic Efficacy against Multidrug-Resistant Bacteria." International Journal of Molecular Sciences 24, no. 20 (2023): 15493. http://dx.doi.org/10.3390/ijms242015493.

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Bacterial antibiotic resistance, especially the emergence of multidrug-resistant (MDR) strains, urgently requires the development of effective treatment strategies. It is always of interest to delve into the mechanisms of resistance to current antibiotics and target them to promote the efficacy of existing antibiotics. In recent years, non-antibiotic compounds have played an important auxiliary role in improving the efficacy of antibiotics and promoting the treatment of drug-resistant bacteria. The combination of non-antibiotic compounds with antibiotics is considered a promising strategy agai
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Aslam, Muhammad Shahbaz, Muhammad Saeed Qureshi, Pervez Iqbal, et al. "GROWING ANTIBIOTIC RESISTANCE IS A MASSIVE THREAT TO HEALTH SYSTEM." Journal of Akhtar Saeed Medical & Dental College 02, no. 01 (2020): 30–38. https://doi.org/10.51127/jamdcv02i01ra01.

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Antibiotic resistance has become a worldwide problem and a massive threat to the health system,particularly in developing countries. A number of factors such as excessive use of antibiotics in the dairy industry, poultry industry, dosage effect, non-professional doctors especially in rural areas, self-medication,and misuse of antibiotics are contributing towards antibiotic resistance. The astonishing genetic capacity of bacteria to resist antibiotics is due to over usage of antibiotics and transmission ofresistant genes to further generations through horizontal gene transfer. The basic mechani
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Nickas, Mark. "A PATENT PRIZE SYSTEM TO PROMOTE DEVELOPMENT OF NEW ANTIBIOTICS AND CONSERVATION OF EXISTING ONES." Pittsburgh Journal of Technology Law and Policy 12 (April 13, 2012): 255–87. http://dx.doi.org/10.5195/tlp.2012.98.

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Antibiotics are valuable drugs that fight bacterial infections, but our supply of antibiotics is at risk. Existing antibiotics gradually lose their effectiveness due to bacterial resistance, and few new antibiotics are being developed to replace them. A variety of models have been proposed to promote the conservation of existing antibiotics or incentivize private actors, i.e., drug companies, to develop new ones. Previous models, however, all encourage investment in antibiotic research and development via patent rights, which also create an incentive to oversell antibiotics. Because the inappr
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Kadirhaz, Muhtar, Yushan Zhang, Naveel Atif, et al. "Primary Healthcare Physicians’ Insufficient Knowledge Is Associated with Antibiotic Overprescribing for Acute Upper Respiratory Tract Infections in China: A Cross-Sectional Study." Antibiotics 13, no. 10 (2024): 923. http://dx.doi.org/10.3390/antibiotics13100923.

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Objectives: Overuse of antibiotics in healthcare remains prevalent and requires urgent attention in China, particularly in primary healthcare (PHC) facilities. This study aimed to describe the patterns of antibiotic prescriptions for acute upper respiratory tract infections (URTIs) in PHC facilities in China and to investigate how PHC physicians’ knowledge influences their antibiotic prescribing behavior. Methods: A cross-sectional survey linking physician questionnaire responses and their prescription data was conducted in Shaanxi Province, China. The proportions of URTI visits that received
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Ombašić, A. "An Insight into Antibiotic Resistance Mechanisms: Microbiological Implications for Public Health." Acta Microbiologica Bulgarica 40, no. 2 (2024): 131–41. http://dx.doi.org/10.59393/amb24400201.

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Antibiotics are antimicrobial agents that target bacteria to treat and prevent bacterial infections. They work by interfering with vital bacterial functions, such as the synthesis of nucleic acid, cell wall, and folate, but also disrupting the plasma membrane and ribosome function. Bacteriostatic antibiotics inhibit bacterial growth and those that are bactericidal kill bacteria. Unfortunately, over time, bacteria have become resistant to antibiotics. This resistance can occur through intrinsic or acquired mechanisms, and bacteria may contain more than one type of bacterial resistance. Bacteria
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Wijaya, Johan Kevin, Bagus Komang Satriyasa, and Ida Ayu Alit Widhiartini. "Antibiotic Prescription for Adult with Acute Respiratory Tract Infections (ARTI) in Public Health Care Center in Denpasar Area during COVID-19 Era." International Journal of Research and Review 9, no. 1 (2022): 510–15. http://dx.doi.org/10.52403/ijrr.20220158.

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Restriction of antibiotic prescribing in pandemic COVID-19 is a dilemma. Establishing an acute respiratory tract infection (ARTI) may underdiagnosed due to limited doctor-patient communication and physical examination. Antibiotics are live saving drug and antibiotics should be prudently used to avoid antibiotic resistance. Understanding the trend of antibiotics prescribing in primary health care services is needed to support antibiotics use appropriate. The aim of this study is at profiling of antibiotics prescriptions for adults with ARTI during COVID-19 era. The qualitative descriptive study
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Dudareva, Maria, Shristi Lama, Keiko Miyazaki, et al. "THE BURDEN OF BROAD-SPECTRUM ANTIBIOTIC USE IN ORTHOPAEDIC INFECTION: SYSTEMIC ANTIBIOTIC PRESCRIBING IN THE SOLARIO TRIAL." Orthopaedic Proceedings 106-B, SUPP_19 (2024): 83. http://dx.doi.org/10.1302/1358-992x.2024.19.083.

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AimThe SOLARIO trial is a randomised controlled non-inferiority trial of antibiotic strategy for bone and joint infection. SOLARIO compares short or long post-operative systemic antibiotic duration, for patients with confirmed infections, who had local antibiotics implanted and no infected metalwork retained when undergoing surgery.This analysis compared systemic antibiotic use in the short (intervention) and long (standard of care) arms of the trial, in the 12 months after index surgery.MethodData was collected prospectively from study randomisation, within 7 days of index surgery. All system
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Duan, Lixia, Chenxi Liu, and Dan Wang. "The General Population’s Inappropriate Behaviors and Misunderstanding of Antibiotic Use in China: A Systematic Review and Meta-Analysis." Antibiotics 10, no. 5 (2021): 497. http://dx.doi.org/10.3390/antibiotics10050497.

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The general population has increasingly become the key contributor to irrational antibiotic use in China, which fuels the emergence of antibiotic resistance. This study aimed to estimate the prevalence of the general population’s irrational use behaviors of antibiotics and identify the potential reasons behind them. A systematic review and meta-analysis were performed concerning four main behaviors relevant to easy access and irrational use of antibiotics and common misunderstandings among the population about antibiotics. Four databases were searched, and studies published before 28 February
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Kanu, Joseph Sam, Mohammed Khogali, Katrina Hann, et al. "National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study." Tropical Medicine and Infectious Disease 6, no. 2 (2021): 77. http://dx.doi.org/10.3390/tropicalmed6020077.

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Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitan
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Oche, Charity, Nike Funmilayo Aladetoun, and Israel Joshua Barde. "Use and abuse of antibiotics in Eriwe farms in Ijebu Ode, Ogun State, Nigeria: A case report." Global Journal of Fisheries Science 6, no. 4 (2024): 97–106. https://doi.org/10.31248/gjfs2024.061.

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Antibiotic use is rampant across freshwater and brackish-water farms. It is routinely used by farmers for disease treatment, prevention and control to maintain high productivity in farms. Antibiotic use and abuse in fish farms have raised concerns regarding public health, environmental sustainability, and the emergence of antibiotic resistance. This study surveyed 60 farms (Grow-out and hatchery ponds) in Ijebu Ode Local Government of Ogun State, Nigeria. The study specifically evaluated the use/abuse of antibiotics among fish farmers, the different forms and types of antibiotics used by farme
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Satari, Hindra Irawan, Agus Firmansyah, and Theresia Theresia. "Qualitative evaluation of antibiotic usage in pediatric patients." Paediatrica Indonesiana 51, no. 6 (2011): 303. http://dx.doi.org/10.14238/pi51.6.2011.303-10.

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Background Antibiotics are among the most commonly prescribed drug for pediatric patients. Inappropriate use of antibiotics can increase morbidity, mortality, patient cost and bacterial antibiotic resistence. Antibiotic uses can be evaluated quantitatively and qualitatively.Objective To qualitatively evaluate antibiotic use in patients using Gyssens algorithm.Methods We performed a descriptive, retrospective study of matient medical records of those admitted to the pediatric ward from January 1 – June 30, 2009. Records were screened for patient antibiotic use, followed by qualitative evaluatio
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Gaygısız, Ümmügülsüm, Timo Lajunen, and Esma Gaygısız. "Community Use of Antibiotics in Turkey: The Role of Knowledge, Beliefs, Attitudes, and Health Anxiety." Antibiotics 10, no. 10 (2021): 1171. http://dx.doi.org/10.3390/antibiotics10101171.

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Turkey has been among the leading countries in antibiotic consumption. As a result of the 4-year National Action Plan for Rational Drug Use, antibiotic prescriptions had declined from 34.9% in 2011 to 24.6% in 2018. However, self-medication with antibiotics without prescription is common, which is not reflected in official statistics. The present study aims at investigating antibiotic use in the community and the factors related to it. A web-based survey was conducted among 945 Turkish-speaking respondents (61.3% female). The questionnaire included questions about antibiotic use for different
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Abedon, Stephen T. "Phage-Antibiotic Combination Treatments: Antagonistic Impacts of Antibiotics on the Pharmacodynamics of Phage Therapy?" Antibiotics 8, no. 4 (2019): 182. http://dx.doi.org/10.3390/antibiotics8040182.

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Bacteria can evolve resistance to antibiotics. Even without changing genetically, bacteria also can display tolerance to antibiotic treatments. Many antibiotics are also broadly acting, as can result in excessive modifications of body microbiomes. Particularly for antibiotics of last resort or in treating extremely ill patients, antibiotics furthermore can display excessive toxicities. Antibiotics nevertheless remain the standard of care for bacterial infections, and rightly so given their long track records of both antibacterial efficacy and infrequency of severe side effects. Antibiotics do
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Lawani-Luwaji, Ebidor. "The Antibiotic Era: A Golden Age and Its Challenges." British Journal of Multidisciplinary and Advanced Studies 5, no. 2 (2024): 57–68. http://dx.doi.org/10.37745/bjmas.2022.0474.

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Antibiotics have revolutionised medicine, helping to reduce infection-related deaths and increase life expectancy globally. They have enabled life-prolonging medical procedures and the foundation for advancements in medicine. This review explores the historical significance of antibiotics in healthcare, underscores the challenges of antibiotic resistance, and emphasises the importance of responsible antibiotic usage. It advocates for developing new antibiotics to combat resistant bacteria and ensure the continued effectiveness of antibiotic therapy in healthcare. A comprehensive search was con
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Pudak Wangi, Putu Ary, and Made Krisna Adi Jaya. "ANTIBIOTICS USAGE OVERVIEW IN ORTHOPEDIC SURGERY PATIENTS AT A HOSPITAL IN BALI." Journal of Pharmaceutical Science and Application 4, no. 2 (2022): 76. http://dx.doi.org/10.24843/jpsa.2022.v04.i02.p05.

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Backgrounds: Antibiotic resistance can be prevented by controlling the use of antibiotics wisely. Based on WHO recommendations, controlling the use of antibiotics is done by grouping antibiotics with the AWaRe category. Objective: This work aims to present an overview of the use of antibiotics in orthopaedic surgery patients as an effort to monitor the use of antibiotics in a hospital in Bali. Methods: Based on the patient's medical record data, the antibiotics used for orthopaedic surgery were calculated and grouped with the AWaRe classification. Result: Results showed that the most prescribe
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Johnston, Deanne, Razeeya Khan, Jacqui Miot, Shirra Moch, Yolande Van Deventer, and Guy Richards. "Usage of antibiotics in the intensive care units of an academic tertiary-level hospital." Southern African Journal of Infectious Diseases 33, no. 4 (2018): 106–13. http://dx.doi.org/10.4102/sajid.v33i4.158.

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Background: The post-antibiotic era is approaching fast as multidrug-resistant bacteria emerge and the antibiotic pipeline slows to a trickle. Antibiotic stewardship requires that antibiotics be used appropriately and as such this study reviewed the utilisation of antibiotics in five adult intensive care units (ICUs) at Charlotte Maxeke Johannesburg Academic Hospital.Methods: A retrospective, cross-sectional record review of admissions to the Coronary, Cardiothoracic, Multidisciplinary, Neurology and Trauma ICUs was conducted over one month. Information from the ICU chart was captured on a mod
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Zeng, Huiping, Jianxue Li, Weihua Zhao, et al. "The Current Status and Prevention of Antibiotic Pollution in Groundwater in China." International Journal of Environmental Research and Public Health 19, no. 18 (2022): 11256. http://dx.doi.org/10.3390/ijerph191811256.

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The problem of environmental pollution caused by the abuse of antibiotics has received increasing attention. However, only in recent years have antibiotic pollution and its risk assessment to the environment been deeply studied. Although there has been a large number of reports about the input, occurrence, destination, and influence of antibiotics in the past 10 years, systemic knowledge of antibiotics in the groundwater environment is still lacking. This review systematically expounds the sources, migration and transformation, pollution status, and potential risks to the ecological environmen
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Felix S.N, John, Bala Krishnan P, and Deepak Hari S.S. "A Prospective Observational Study on Evaluating the Appropriateness and Prescription Pattern of Restricted Antibiotics in a Quaternary Care Hospital." International Journal of Health Sciences and Research 14, no. 9 (2024): 45–54. http://dx.doi.org/10.52403/ijhsr.20240906.

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Aim: To evaluate the appropriateness of Restricted Antibiotics in accordance with Indian Council of Medical Research (ICMR) guidelines and Prescription Pattern of Restricted Antibiotics in a quaternary care hospital. Methodology: This prospective observational study included the in-patients of different wards in a quaternary care hospital who have been prescribed Restricted Antibiotics in the drug chart. The appropriateness of Restricted antibiotic use is assessed on the basis of the ICMR guidelines. The appropriateness of Restricted Antibiotics was verified, according to three main criteria:
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Fruitwala, Asma Mohd Shoeb, Kanchan Shah, Jayant Landge, Nilesh Ubale, Mahesh Pund, and Shelly Sharma. "Survey on antibiotics prescription and resistance on medical and dental practitioners." Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology 10, no. 1 (2024): 27–30. http://dx.doi.org/10.18231/j.jooo.2024.005.

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The objective of this research was to find out how much medical and dental professionals and interns in Maharashtra knew about the current situation regarding usages of antibiotics and its over usage which leads to antibiotic resistance over time. A self-administered survey created with Google Forms that asks about the extent of usage of antibiotics.A survey was conducted among the medical and dental professionals practicing in the state of Maharashtra from 01 September 2023 to 15 October 2023 analyse the extent of usage of antibiotics among patients and to draw their attention towards the exc
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Herawati, Fauna, Abdul Rahem, Dwi Handayani, and Rika Yulia. "ANTIBIOTIC PROPHYLACTICS ON CURETTAGE FOR PREVENTING PELVIC INFLAMMATORY DISEASE EVENTS: IS IT NECESSARY?" Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 267. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.27817.

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Objective: This study aimed to compare pelvic inflammatory disease (PID) symptoms in curettage procedure with three antibiotic prophylaxis strategies.Methods: The patients were allocated to three Groups (A, B, and C). Group A was patients receiving prophylactic antibiotics and post-curettage antibiotics, Group B received prophylactic antibiotics without post-curettage antibiotics, and Group C did not receive prophylactic antibiotics but received post-curettage antibiotics. The outcomes measured to identify the occurrence of PID symptoms included leukocytes, erythrocyte sedimentation rate, temp
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Zimbwe, Kauke Bakari, Yusto Julius Yona, Charity Alphonce Chiwambo, et al. "Surveillance of antibiotics use in inpatients at Benjamin Mkapa Zonal Referral Hospital in Dodoma, Tanzania: a point prevalence survey." BMJ Open 14, no. 8 (2024): e083444. http://dx.doi.org/10.1136/bmjopen-2023-083444.

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ObjectiveTo assess antibiotics prescribing and use patterns for inpatients at Benjamin Mkapa Zonal Referral Hospital (BMH) using the WHO-Point Prevalence Survey (WHO-PPS).DesignA cross-sectional survey.SettingThe Benjamin Mkapa Zonal Referral Hospital, Dodoma, Tanzania.ParticipantsInpatient prescriptions, regardless of whether antibiotics were prescribed (n=286) on the day of PPS.Outcome measuresOur study analysed the prevalence of antibiotic use at BMH for inpatients, the type of antibiotics used, the indications for use and the proportion of oral and parenteral antibiotics. We also assessed
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Frost, Holly M., Bryan C. Knepper, Katherine C. Shihadeh, and Timothy C. Jenkins. "A Novel Approach to Evaluate Antibiotic Utilization Across the Spectrum of Inpatient and Ambulatory Care and Implications for Prioritization of Antibiotic Stewardship Efforts." Clinical Infectious Diseases 70, no. 8 (2019): 1675–82. http://dx.doi.org/10.1093/cid/ciz466.

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Abstract Background Antibiotic overuse remains a significant problem. The objective of this study was to develop a methodology to evaluate antibiotic use across inpatient and ambulatory care sites in an integrated healthcare system to prioritize antibiotic stewardship efforts. Methods We conducted an epidemiologic study of antibiotic use across an integrated healthcare system on 12 randomly selected days from 2017 to 2018. For inpatients and perioperative patients, administrations of antibiotics were recorded, whereas prescriptions were recorded for outpatients. Results On the study days, 10.9
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Manas, Chakraborty Arindam Chakraborty Payel Mukherjee. "Antibiotic Resistance: The Global Crisis." Journal of Pharma Research 9, no. 3 (2020): 5. https://doi.org/10.5281/zenodo.3833718.

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<strong><em>ABSTRACT</em></strong> <strong>A</strong>ntibiotics are secondary metabolites microorganism effective against other microorganisms. For decades antibiotics are used for therapeutic purpose. Excess use, inappropriate use of antibiotics causes antibiotic resistance. It affects on public health as well as economy. Positive efforts needed to minimize or overcome these global issue through studying the mechanism of action of antibiotics, awareness through healthcare system and social awareness also. Alternative approaches should be introduced like vaccines, Probiotics and antibiotics in
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Srivastava, Rishi, Rajesh Sharma, Shweta Sonam, and Shree P. Tiwari. "Production of antibiotics by bacterial isolates from Gomti River sediments, India." Ecology, Environment and Conservation 31, no. 2 (2025): 826–32. https://doi.org/10.53550/eec.2025.v31i02.065.

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Natural products obtained from microorganisms are major sources of antibiotics but discovery of new antibiotics is an inextricable challenge. The resistance-guided approach of isolation exploits the self-protection mechanism of antibiotic producers to isolate the microorganisms producing antimicrobial compounds of selected antibiotic scaffolds. The frequency of new antibiotic discovery from the conventional sources has been decreased significantly. Gomti river is still unexplored regarding isolation of antibiotic producing bacterial strains. In the current study, antibiotic-producing bacteria
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Zhang, Tie, Chun Guang Wang, Wei Han, et al. "Serotype Identification and Drug Sensitive Test of the Pathogenic Escherichia coli." Advanced Materials Research 96 (January 2010): 207–13. http://dx.doi.org/10.4028/www.scientific.net/amr.96.207.

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Thirty-eight isolates of Escherichia coli (E.coli) were isolated from chickens either ill or dead suspected with E.coli. These chickens come from chicken breeding farms in the districts of Baoding, Qinhuangdao and Beijing of China. The results of the antibiotics sensitivity test in the thirty-eight isolates to twenty-four kinds of antibiotics show that all isolates have presented antibiotic resistance disparately as well as multiresistance. All isolates are sensitive to Cephalosporins antibiotics and Aminoglycosides antibiotics such as Amikacin, Cefazolin, Cefradine, Cefoperazone and Ceftriaxo
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Marwan, Saleh Alsolmi Hatem Hassan Mulla Sulafa Taher A. Sindi Njood Waleed M. Nazer Mukhtar Mohammed Hussain Almarzooq Mustafa Abdulrazaq Alhamood Zainab Hashem Alsadah Azhar Abdullah Alqattan Mohammed Saleh Mohsen Alharthi Kauther Mohammed S. Alsadeq Ahmed Fakhri H. AlSabi. "AWARENESS LEVEL OF PARENTS TOWARD ANTIBIOTICS THOSE ARE PRESCRIBED TO THEIR CHILDREN IN AL-DAMMAM CITY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 15969–72. https://doi.org/10.5281/zenodo.2205473.

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<strong><em>Background: </em></strong><em>Misuse of antibiotics is worldwide problem and annoying pediatricians. This misuses result in the increase the prevalence of one of global health problem which is antibiotic Resistance. Many studies mentioned that misusing of antibiotics is related to antibiotic resistance. The main reason of antibiotics misuse is low public awareness towards antibiotics indications. Also, patient&#39;s knowledge and practice with the antibiotic like self-prescription is common in developing countries. The antibiotics prescribed from private pharmacies are given to par
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Sobierajski, Tomasz, Beata Mazińska, Wioleta Chajęcka-Wierzchowska, Marcin Śmiałek, and Waleria Hryniewicz. "Antimicrobial and Antibiotic Resistance from the Perspective of Polish Veterinary Students: An Inter-University Study." Antibiotics 11, no. 1 (2022): 115. http://dx.doi.org/10.3390/antibiotics11010115.

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The phenomenon of antibiotic resistance is a global problem that affects the use of antibiotics by humans and animal husbandry. One of the primary reasons for the growing phenomenon of antibiotic resistance is the over-prescription of antibiotics by doctors in human medicine and the overuse of antibiotics in industrial animal farming. Adequate education of veterinary medical students on the use of antibiotics in animal husbandry may reduce antibiotic resistance. For this reason, a survey was conducted among students at four primary research and didactic centers teaching veterinary medicine in
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Abejew, Asrat Agalu, Gizachew Yismaw Wubetu, and Teferi Gedif Fenta. "A six years trend analysis of systemic antibiotic consumption in Northwest Ethiopia." PLOS ONE 19, no. 1 (2024): e0290391. http://dx.doi.org/10.1371/journal.pone.0290391.

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Background Consumption of antibiotics, a major global threat to public health, is perhaps the key driver of antibiotic resistance. Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. This study assessed antibiotic consumption trends during the last six years in the Bahir Dar branch of the Ethiopian pharmaceutical supply agency (EPSA), Northwest Ethiopia, in 2022. Methods Retrospective data were collected in August 2022 based on antibiotic distribution data from the Bahir Dar Brach of EPSA from July 2016 to June 2022. Data were analyzed according to the Anatomic T
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Outterson, Kevin, John H. Powers, Enrique Seoane-Vazquez, Rosa Rodriguez-Monguio, and Aaron S. Kesselheim. "Approval and Withdrawal of New Antibiotics and other Antiinfectives in the U.S., 1980–2009." Journal of Law, Medicine & Ethics 41, no. 3 (2013): 688–96. http://dx.doi.org/10.1111/jlme.12079.

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Antibiotic use triggers evolutionary and ecological responses from bacteria, leading to antibiotic resistance and harmful patient outcomes. Two complementary strategies support long-term antibiotic effectiveness: conservation of existing therapies and production of novel antibiotics. Conservation encompasses infection control, antibiotic stewardship, and other public health interventions to prevent infection, which reduce antibiotic demand. Production of new antibiotics allows physicians to replace existing drugs rendered less effective by resistance.In recent years, physicians and policymaker
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Deveswaran, R. "Revolutionizing Antibiotics: Breakthroughs in Discovery and Development." Journal of Medical Pharmaceutical and Allied Sciences 14, no. 2 (2025): 68–74. https://doi.org/10.55522/jmpas.v14i2.6873.

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Antibiotics are chemical substances that inhibit the growth of bacteria and other microbes. Antibiotics should cause minimal or no toxicity and should be effective against a particular infection. The early era of 1940-1960s is considered as golden age of antibiotics. Most of the antibiotics are becoming resistant to various bacteria, fungi and spores, leading to necessity of new antibiotics to combat resistance. Significant technological advances have provided researchers access to biological events and repositioned their mind set for antibiotic research. Target based screening, cell based ade
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Merrett, Gemma L. Buckland, Gerald Bloom, Annie Wilkinson, and Hayley MacGregor. "Towards the just and sustainable use of antibiotics." Journal of Pharmaceutical Policy and Practice 9, no. 1 (2016): 31. https://doi.org/10.1186/s40545-016-0083-5.

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The emergence and spread of antibiotic resistant pathogens poses a big challenge to policy-makers, who need to oversee the transformation of health systems that evolved to provide easy access to these drugs into ones that encourage appropriate use of antimicrobials, whilst reducing the risk of resistance. This is a particular challenge for low and middle-income countries with pluralistic health systems where antibiotics are available in a number of different markets. This review paper considers access and use of antibiotics in these countries from a complex adaptive system perspective. It high
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