Academic literature on the topic 'Antibody maintenance'

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Journal articles on the topic "Antibody maintenance"

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Manz, Rudolf A., Anja E. Hauser, Falk Hiepe, and Andreas Radbruch. "MAINTENANCE OF SERUM ANTIBODY LEVELS." Annual Review of Immunology 23, no. 1 (2005): 367–86. http://dx.doi.org/10.1146/annurev.immunol.23.021704.115723.

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Golfier, Camille, and Gilles Salles. "Antibody Therapy Maintenance in Follicular Lymphoma." Hematology/Oncology Clinics of North America 34, no. 4 (2020): 689–99. http://dx.doi.org/10.1016/j.hoc.2020.02.005.

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Weinberger, Birgit, Michael Keller, and Beatrix Grubeck-Loebenstein. "Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hampered by latent infection with Cytomegalovirus." Immunity & Ageing 14, no. 1 (2017): 16. https://doi.org/10.1186/s12979-017-0099-y.

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<strong>Abstract: </strong>Many currently used vaccines are less immunogenic in the elderly compared to young adults. The impact of latent infection with Cytomegalovirus (CMV) on vaccine-induced antibody responses has been discussed controversially. We have demonstrated that recall responses to diphtheria vaccination are frequently insufficient in elderly persons and that antibody concentrations decline substantially within 5 years. In the current study we show that within a cohort of healthy elderly (<i>n</i> = 87; median age 71 years, range 66–92) antibody responses to a booster vaccination
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Inamine, Ayako, Yoshitaka Okamoto, Masashi Arima, and Takeshi Tokuhisa. "The maintenance of the IgE antibody secreting cells." Journal of Japan Society of Immunology & Allergology in Otolaryngology 29, no. 3 (2011): 215–20. http://dx.doi.org/10.5648/jjiao.29.215.

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Cattran, Daniel C., and Michelle A. Hladunewich. "Maintenance Immunosuppression in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis." American Journal of Kidney Diseases 57, no. 6 (2011): 818–21. http://dx.doi.org/10.1053/j.ajkd.2011.03.006.

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Chistyakova, Elena, and Rashida Orlova. "Maintenance therapy with monoclonal antibodies in metastatic HER2-positive breast cancer: A review of studies." Vestnik of Saint Petersburg University. Medicine 18, no. 1 (2023): 63–69. http://dx.doi.org/10.21638/spbu11.2023.105.

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Maintenance therapy is a medical treatment after achieving stabilization, partial or complete response by the first line therapy of a metastatic malignant tumor. The goals of such treatment are to maintain the effect of the first line therapy, to increase progression-free survival, and, in some cases, overall survival. Targeted monoclonal antibody therapy is a maintenance treatment option widely used in clinical practice for metastatic HER2-positive breast cancer, but it remains one of the least studied. This analysis of available world studies was carried out in order to form an idea about th
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Prechl, József. "A generalized quantitative antibody homeostasis model: maintenance of global antibody equilibrium by effector functions." Clinical & Translational Immunology 6, no. 11 (2017): e161. http://dx.doi.org/10.1038/cti.2017.50.

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Guillevin, Loïc, and Benjamin Terrier. "Maintenance of Remission in antineutrophil cytoplasm antibody-associated vasculitides." International Journal of Rheumatic Diseases 22 (April 19, 2018): 100–104. http://dx.doi.org/10.1111/1756-185x.13303.

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Kirchner, V. A., T. M. Suszynski, D. M. Radosevich, et al. "Anti-CD25 Antibody (Daclizumab) Maintenance Therapy in Pancreas Transplantation." Transplantation Proceedings 42, no. 6 (2010): 2003–5. http://dx.doi.org/10.1016/j.transproceed.2010.05.083.

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Yen, Cheng-Chieh, Shang-Yi Lin, Szu-Chia Chen, Yi-Wen Chiu, Jer-Ming Chang, and Shang-Jyh Hwang. "COVID-19 Vaccines in Patients with Maintenance Hemodialysis." Journal of Personalized Medicine 11, no. 8 (2021): 789. http://dx.doi.org/10.3390/jpm11080789.

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The COVID-19 pandemic has infected more than 180 million people and caused more than 3.95 million deaths worldwide. In addition to personal hygiene, augmented cleaning, social distancing, and isolation, vaccine development and immunization are essential for this highly contagious disease. Patients with maintenance hemodialysis (MHD) have a greater risk of COVID-19 infection owing to their comorbidities, defective immunity, and repeated crowded in-center dialysis settings. However, many patients hesitate to get vaccinated because of their misunderstandings. The Efficacy of COVID-19 vaccination
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Dissertations / Theses on the topic "Antibody maintenance"

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Ping, Yeh Chang, and 葉張平. "Survey of canine antibody against rabies virus in Taichung and evaluation the maintenance of antibody after infected commercial rabies vaccine." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/08674420113505764797.

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碩士<br>國立中興大學<br>獸醫學系<br>87<br>This research is to evaluate the immune status of dogs in Taichung to rabies virus, a total of 1000 serum samples were collected form domestic dogs(500) and stray dogs(500) in June 1998 to May 1999, and tested for antibodies with the ELISA. 49% of domestic dogs had antibodies against rabies virus and 27% of stray dogs had antibodies against rabies virus, indicating that the vaccination strategy for preventing rabies outbreaks in dogs is incompletely practiced in Taichung. And owners in Taichung have an insufficient concept to epidemic prevention of rabies. Further
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Kazadi, David. "RNA:DNA Heteroduplex Resolution in B-Lymphocyte Immunoglobulin Diversification and Genomic Maintenance." Thesis, 2016. https://doi.org/10.7916/D8319VWQ.

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Immunoglobulin (Ig) gene diversification plays an essential role in adaptive immunity. Faced with a continuous yet varied stream of self, non-self, and possibly harmful molecules, many organisms have mechanisms in their arsenal that have evolved to match the diversity of the antigens they encounter. In humans and mice, developing B and T lymphocytes go through a first round of genomic alteration — V(D)J recombination — in the bone marrow and the thymus, respectively. B cells can subsequently undergo two additional Ig gene diversification processes in secondary lymphoid tissues. Through somatic
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Kup, Yi-Ting, and 郭奕廷. "The effects of T cell immunity on the production and maintenance of HBV core antibody." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/53538162888799598348.

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碩士<br>國立臺灣大學<br>微生物學研究所<br>102<br>More than 240 million people have chronic Hepatitis B virus (HBV) infection, and about 600,000 people die due to acute or chronic HBV infection every year. The therapeutic course of chronic HBV infection is very long. Viral relapse is common when anti-virus treatment is stopped. There is no indicator providing the doctor with confidence to know when to stop the therapeutic course. Clearance of hepatitis infection relies on the host immunity, so the quality of host immunity, particularly T cell immunity, should be a good indicator for prognosis before treatment
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Books on the topic "Antibody maintenance"

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Salker, Rajas. Microbial antibody screening for the maintenance of a safe blood supply. Brunel University, 1990.

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Dörner, Thomas, and Peter E. Lipsky. Cellular side of acquired immunity (B cells). Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0050.

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B cells have gained interest in rheumatoid arthritis (RA) beyond being the precursors of antibody-producing plasma cells since they are also a broader component of the adaptive immune system. They are capable of functioning as antigen-presenting cells for T-cell activation and can produce an array of cytokines. Disturbances of peripheral B-cell homeostasis together with the formation of ectopic lymphoid neogenesis within the inflamed synovium appears to be a characteristic of patients with RA. Enhanced generation of memory B cells and autoreactive plasma cells producing IgM-RF and ACPA-IgG ant
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Harper, Lorraine, and David Jayne. The patient with vasculitis. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0160.

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The goals of treatment in renal vasculitis are to stop vasculitic activity and recover renal function. Subsequent strategies are required to prevent vasculitis returning and to address longer-term co-morbidities caused by tissue damage, drug toxicity, and increased cardiovascular and malignancy risk.Cyclophosphamide and high-dose glucocorticoids remain the standard induction therapy with alternative immunosuppressives, such as azathioprine, to prevent relapse. Plasma exchange improves renal recovery in severe presentations. Refractory disease resulting from a failure of induction or remission
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Jayne, David. Treatment of ANCA-associated vasculitis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0132.

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The goals of treatment in anti-neutrophil cytoplasm antibody (ANCA) vasculitis are to stop vasculitic activity, to prevent vasculitis returning, and to address longer-term comorbidities caused by tissue damage, drug toxicity, and increased cardiovascular and malignancy risk. Cyclophosphamide and high-dose glucocorticoids remain the standard induction therapy with alternative immunosuppressives, such as methotrexate or azathioprine, to prevent relapse. Refractory disease resulting from a failure of induction or remission maintenance therapy requires alternative agents and rituximab has been par
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Book chapters on the topic "Antibody maintenance"

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Miller, Aaron E., Tracy M. DeAngelis, Michelle Fabian, and Ilana Katz Sand. "On the Right Tract." In Neuroimmunology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190693190.003.0020.

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Paraneoplastic myelopathies are uncommon, but maintenance of a high index of clinical suspicion is critical, as the neurological syndrome often predates discovery of an underlying malignancy and can facilitate early detection and potentially improve prognosis. Most paraneoplastic myelopathies are associated with additional neurological symptomatology, such as encephalitis, peripheral neuropathy, or cerebellar ataxia, due to the specific, respective auto-antibodies involved. Anti-Hu antibody, identified in our patient, appears to be the most common antibody, followed by amphiphysin, and collaps
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"Management of rejection following cardiac transplantation." In Cardiopulmonary transplantation and mechanical circulatory support, edited by Maziar Khorsandi, Steven Tsui, John Dark, et al. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/med/9780192867612.003.0020.

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Abstract Since refining the technical aspects of heart transplantation, management of immunosuppression following heart transplantation has formed the cornerstone of management of such critically ill patients. There is variability between institutions in terms of immunosuppression regimen protocols and there are modifications that should be made on a case-by-case basis. We shall discuss rejection surveillance as well as various forms of rejection including cellular and antibody mediated. We will also touch on desensitization protocols for the management of sensitized recipients. This chapter f
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Dörner, Thomas, and Peter E. Lipsky. "Cellular side of acquired immunity (B cells)." In Oxford Textbook of Rheumatology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0050_update_001.

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B cells have gained interest in rheumatoid arthritis (RA) beyond being the precursors of antibody-producing plasma cells since they are also a broader component of the adaptive immune system. They are capable of functioning as antigen-presenting cells for T-cell activation and can produce an array of cytokines. Disturbances of peripheral B-cell homeostasis together with the formation of ectopic lymphoid neogenesis within the inflamed synovium appears to be a characteristic of patients with RA. Enhanced generation of memory B cells and autoreactive plasma cells producing IgM-RF and ACPA-IgG ant
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Law, Soi-Cheng, Pascale Wehr, Harriet Purvis, and Ranjeny Thomas. "Dendritic cells and T cells in rheumatoid arthritis." In Oxford Textbook of Rheumatoid Arthritis. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198831433.003.0008.

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Dendritic cells (DCs) are specialized antigen-presenting cells which link the innate and adaptive immune responses, activating and priming effector CD4+ T cells, cross-presenting antigen to CD8+ T cells, and promoting B-cell antibody production. DCs also play important roles in the maintenance of immune tolerance. DCs and T cells underpin the basis of the autoimmune response in rheumatoid arthritis. In this chapter we describe the function of DCs and the response of T cells in rheumatoid arthritis pathogenesis, introduce the DC and T-cell players and their function in the immune system, then r
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Karagiannis, Georgios, Diana Garcia Saez, Margaret M. Burke, André R. Simon, and Nicholas R. Banner. "Heart transplantation." In Oxford Textbook of Heart Failure, edited by Andrew L. Clark, Roy S. Gardner, and Theresa A. McDonagh. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780198766223.003.0061.

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Heart transplantation is the reference standard treatment for advanced acute and chronic heart failure, although limited by the scarcity of donor hearts. Careful selection of transplant candidates is therefore essential in combination with optimal donor recipient matching. In the current era, most surgeons use the bicaval heart transplant technique. Approximately half of the patients receiving a heart transplant are on mechanical circulatory support. Allograft rejection is clinically categorized according to its temporal occurrence (hyper-acute, acute, and chronic) and by the underlying mechan
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Baker, Kenneth F., and John D. Isaacs. "Rheumatoid arthritis." In Oxford Textbook of Medicine, edited by Richard A. Watts. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0446.

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Rheumatoid arthritis is a common autoimmune disease characterized by both synovial and systemic inflammation. Synovitis classically presents as a symmetrical destructive polyarthritis affecting the hands and feet typified by episodic pain, stiffness, and swelling. Systemic inflammation leads to a range of extra-articular manifestations including organ involvement (e.g. interstitial lung disease, scleritis), constitutional features (e.g. fatigue, depression) and other complications (e.g. accelerated atherosclerosis, nerve and spinal cord compression). Rheumatoid arthritis is a clinical diagnosi
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Clerkin, Kevin J., and Maryjane A. Farr. "Orthotopic Heart Transplant Rejection and Immunosuppression." In Cardiothoracic Critical Care. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190082482.003.0026.

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This chapter focuses on orthotopic heart transplant rejection. Hyperacute rejection is a catastrophic complication that occurs early post-transplantation. This type of rejection is most often due to pre-formed donor-specific anti–human leukocyte antigen antibodies or an ABO blood type mismatch and is rarely seen in the current era because pre-transplant virtual and prospective crossmatch has become routine practice. Meanwhile, immune activation of recipient T cells against the cardiac allograft causes acute cellular rejection (ACR). Treatment of ACR will vary depending on the grade of rejectio
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Badu, Kingsley, Amma Aboagyewa Larbi, and Kwadwo Boampong. "Malaria Elimination: The Role and Value of Sero-Surveillance." In Current Topics and Emerging Issues in Malaria Elimination. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.97131.

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As countries move from intense malaria transmission to low transmission there will be a demand for more sensitive tools and approaches in tracking malaria transmission dynamics. Surveillance tools that are sensitive in tracking real time infectious bites as well as infectious reservoir will be preferred to counting number of cases in the hospital or parasite prevalence. The acquisition and maintenance of anti-malarial antibodies is a direct function of parasite exposure, seroprevalence rates has been used as an efficient tool in assessing malaria endemicity and confirming malaria elimination.
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Watkins, Elyse A., and Robert Vassar. "BACE Inhibitor Clinical Trials for Alzheimer’s Disease." In Advances in Alzheimer’s Disease. IOS Press, 2024. https://doi.org/10.3233/aiad240005.

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The amyloid hypothesis posits that the amyloid-β aggregates in the brain initiate a cascade of events that eventually lead to neuron loss and Alzheimer’s disease. Recent clinical trials of passive immunotherapy with anti-amyloid-β antibodies support this hypothesis, because clearing plaques led to better cognitive outcomes. Orally available small molecule BACE1 inhibitors are another approach to slowing the buildup of plaques and thereby cognitive worsening by preventing the cleavage of amyloid-β protein precursor (AβPP) into amyloid-β peptide, the major component of plaques. This approach is
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Jardetzky, T. "The Interaction of Antigens and Superantigens with the Human Class II Major Histocompatibility Complex Molecule HLA-DR1." In Biological NMR Spectroscopy. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780195094688.003.0022.

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The initiation and maintenance of an immune response to pathogens requires the interactions of cells and proteins that together are able to distinguish appropriate non-self targets from the myriadof self-proteins (Janeway and Bottomly, 1994). This discrimination between self and non-self is in part accomplished by three groups of proteins of the immune system that have direct and specific interactions with antigens: antibodies, T cell receptors (TcR) and major histocompatibility complex (MHC) proteins. Antibodies and TcR molecules are clonally expressed by the B and T cells of the immune syste
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Conference papers on the topic "Antibody maintenance"

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Guisado Gil, AB, M. Muñoz Burgos, FJ Bautista Paloma, FJ Garcia Hernandez, and B. Santos Ramos. "4CPS-121 Cost-minimisation analysis of maintenance therapy of antineutrophil cytoplasm antibody-associated vasculitides." In 24th EAHP Congress, 27th–29th March 2019, Barcelona, Spain. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/ejhpharm-2019-eahpconf.270.

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Bussel, J. "FOR MODULATION AS A MEANS OF ELEVATING THE PLATELET COUNT IN ITP." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644761.

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ITP is an autoantibody-mediated disease which would logically be treated by decreasing the level of autoantibody. However, the most exciting developments in understanding the pathophysiology of the thrombocytopenia and its treatment involve a better understanding of the MPS FcR system and ways in which it can be modulated. This work has focussed on phagocytic paralysis or FcR blockade (FcRBl): the slowing of destruction of antibody-coated platelets despite the persistent presence of antibody on the surface of the platelet.Several areas have been explored in learning about the MPS system. Inves
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Castro, Ana Rita Motta, Livia Lima, Larissa Bandeira, et al. "Hepatitis B: changes in epidemiological features of Afrodescendant communities in Central Brazil." In XIII Congresso da Sociedade Brasileira de DST - IX Congresso Brasileiro de AIDS - IV Congresso Latino Americano de IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/dst-2177-8264-202133p142.

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Introduction: Hepatitis B virus (HBV) infection is still a concern in vulnerable populations. In a study performed by our team in 1999–2003 in two Afro-Brazilian communities, Furnas dos Dionísios (FD) and São Benedito (SB), high prevalence rates of HBV exposure (42.7% and 16.0%, respectively), high susceptibility to HBV (55.3% and 63.0%, respectively) and low HBV vaccination like profile rates (2.0% and 21.0%, respectively) were observed. Objective: In 2015–2016, we reassessed epidemiological and molecular features of HBV in these two communities to verify the impact of health actions adopted
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Matsumoto, T., K. Kanamaru, Y. Sugiyama, and K. Deguchi. "HEMATOLOGICAL CHARACTERISTICS OF PREGNANT BLOOD AND LOCALIZATION OF THROMBOMODULIN IN HUMAN PLACENTAL VILLOUS TISSUE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644299.

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Thrombomodulin(TM) is a cell surface protein found on endothelial cell that binds thrombin and increases thrombin's ability to activate protein C(PC). In the present study, we examined hematological characteristics and behavior of plasma PC level in pregnant women and localization of TM in the placental villous tissue. The results obtained are reported here. Cubital venous blood of 20 normal pregnants, 8 purperants and 60 non-pregnants. PC antigen(PC:Ag) was measured by the Laurell's technique using Assera plate-proteinC. Localization of TM was determined in such a way that the villous tissue
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Levine, P. H. "ACQUIRED IMMUNODEFICIENCY SYNDROME, HUMAN IMMUNODEFICIENCY VIRUS AND HEMOPHILIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644752.

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Less than 15 years ago the National Heart, Lung and Blood Institute surveyed physicians in the United States in order to characterize the demographics of hemophilia. The average age of persons with hemophilia in the United States was found to be 11.5 years old. By 10 years later, the life expectancy was predicted to be normal, and indeed the average age of persons with hemophilia in the U.S. is now in the early twenties. Early, intensive and predictably efficacious control of hemorrhage has made this result possible, and the therapeutic product which has allowed such control is commercial clot
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Reports on the topic "Antibody maintenance"

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Bray, Elizabeth, Zvi Lerner, and Alexander Poljakoff-Mayber. The Role of Phytohormones in the Response of Plants to Salinity Stress. United States Department of Agriculture, 1994. http://dx.doi.org/10.32747/1994.7613007.bard.

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Salinity is an increasing problem in many irrigated areas of crop production and is a significant factor in reducing crop productivity. Developmental, physiological, and molecular responses to salinity were studied in order to improve our understanding of these responses. Improvements in our understanding of plant responses to salinity are necessary in order to develop crops with improved salt tolerance. Previously, in Israel, it was shown that Sorghum biccolor can adapt to an otherwise lethal concentration of NaCl. These experiments were refined and it was shown that there is a specific windo
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