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Relevant bibliographies by topics / Anticancer compound

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Academic literature on the topic 'Anticancer compound'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Anticancer compound"

1

Yaprak, Yıldız, HülyaAkgün, Sipahi Hande, Deniz İnci, and Berk Barkın. "Synthesis, Characterization and Potential Anticancer and Antimicrobial Activities of New Phthalamide Derivatives." Pharmaceutical and Chemical Journal 6, no. 1 (2019): 72–83. https://doi.org/10.5281/zenodo.13931678.

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A series of N<sup>1</sup>,N<sup>2</sup>-bis [(2-substitutedphenyl)ethyl]phthalamide (compounds <strong>1-10</strong>) and 3-nitro-N<sup>1</sup>, N<sup>2</sup>-bis [(2-substitutedphenyl)ethyl]phthalamide (compounds <strong>11-20</strong>) were synthesized. Their structures and purity were analyzed by IR, <sup>1</sup>H-NMR spectra and elemental analysis. The compounds were evaluated for their <em>in vitro </em>cytotoxicity against the MCF7 and Hep3B cancer cell lines. Cytotoxicity screening revealed that N<sup>1</sup>,N<sup>2</sup>-bis[2-(2,4-dichlorophenyl)ethyl]phthalamide (compound<strong> 5<

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2

Firdaus, Firdaus, Nunuk Hariani Soekamto, Seniwati Seniwati, et al. "Phenethyl p-coumarate and N-phenethyl-p-coumaramide: Synthesis, Characterization, Docking Studies, and Anticancer Activity through P388 Cell." Sains Malaysiana 51, no. 4 (2022): 1085–97. http://dx.doi.org/10.17576/jsm-2022-5104-11.

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Most p-coumaric acid derivatives and molecules containing phenethyl moiety have a potential in anticancer activity. Thus, combining a p-coumaroyl group and a phenethyl moiety in one compound will increase anticancer activity. The principal objective of this research was to incorporate p-coumaroyl and phenethyl moieties to form an ester, phenethyl p-coumarate (5), and an amide, N-phenethyl-p-coumaramide (6), then tested their anticancer activity using P388 leukemia murine cells. The characterization by FTIR method, compound 5 gave a strong absorption band of alkyl C-O bond that appears at 1165,

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Haggam, Reda Ahmed, Mohamed Gomma Assy, Mohamed Hassan Sherif, and Mohamed Mohamed Galahom. "A series of 1,3-imidazoles and triazole-3-thiones based thiophene-2-carboxamides as anticancer agents: Synthesis and anticancer activity." European Journal of Chemistry 9, no. 2 (2018): 99–106. http://dx.doi.org/10.5155/eurjchem.9.2.99-106.1701.

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By addition of semicarbazide or phenylhydrazine hydrochloride to thienoylisothiocyanate (1) resulted in building of thiosemicarbazide derivative (2), triazole derivative (4) and thiophene-2-carboxamide (5), respectively. Basic cyclization of compound 2 led to formation of oxadiazine (3). Synthesis of thiadiazine derivative (6) was achieved via reaction of compound 5 and maleic anhydride in triethyl amine. Heating of compound 5 with ethyl chloroacetate or sodium ethoxide produced thiadiazine derivative (7) and triazolethione (8), respectively. Thiosemicarbazide derivative 11 was synthesized by

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Sonawane, Ganesh, Shweta Sharma, and Ritu Gilhotra. "Synthesis, Characterization and Pharmacological Screening of 1,3,4-Oxadiazoles." Asian Journal of Chemistry 36, no. 6 (2024): 1436–46. http://dx.doi.org/10.14233/ajchem.2024.31776.

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Two series of 1,3,4-oxadiazole scaffolds (10a-j & 12a-j) were synthesized and comprehensively characterized using IR, NMR and mass spectra. Subsequently, the synthesized compounds underwent screening for anticancer activity against HepG2 and MCF-7 cell lines. All the 20 compounds exhibited substantial anticancer activity with compounds 10b and 10e demonstrating particularly significant activity surpassing that of the standard 5-fluorouracil. Significantly, compound 10b displayed superior efficacy compared to compound 10e, prompting its selection for further in vivo assessment against dieth

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Thiriveedhi, Arunkumar, Ratnakaram Venkata Nadh, Navuluri Srinivasu, and Narayana Murthy Ganta. "Novel Pyrazolyl Benzoxazole Conjugates: Design, Synthesis, Molecular Docking Studies and in vitro Anticancer Activities." Letters in Organic Chemistry 16, no. 8 (2019): 619–26. http://dx.doi.org/10.2174/1570178615666181022141919.

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Nowadays, hybrid drugs have gained a significant role in the treatment of different health problems. Most of the hybrid molecules with different heterocyclic moieties were proved to be potent anti-tumor agents in cancer chemotherapy. Hence, the present study is aimed at the evaluation of in vitro anticancer activity of novel hybrid molecules (pyrazolyl benzoxazole conjugates) and to investigate their anticancer activity by molecular docking studies. Designed, synthesized and characterized the novel pyrazolyl benzoxazole conjugates. Anticancer activity of these compounds was determined by SRB a

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Akrami, Hamidreza, Bibi Fatemeh Mirjalili, Omidreza Firuzi, et al. "Cytotoxic Activity and DNA Binding Property of New Aminopyrimidine Derivatives." Letters in Drug Design & Discovery 17, no. 5 (2020): 640–54. http://dx.doi.org/10.2174/1570180816666190712102119.

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Background: Chromene and anilinopyrimidine heterocyclics are attractive anticancer compounds that have inspired many researchers to design novel derivatives bearing improved anticancer activity. Methods: A series of pyrimidine-fused benzo[f]chromene derivatives 6a-x were synthesized as anticancer hybrids of 1H-benzo[f]chromenes and anilinopyrimidines. The inhibitory activity of the synthesized compounds 6a-x against cell viability of human chronic myelogenous leukemia (K562), human acute lymphoblastic leukemia (MOLT-4) and human breast adenocarcinoma (MCF-7) cell lines was evaluated using MTT

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Honavar, Premanand M., Bhuvanesh Sukhlal Kalal, Ranjith Raj, et al. "Thiazolyl-Thiazolidinone Conjugated Pyrazoles as Potential Anticancer and Antibacterial Agents and Molecular Docking Studies." Asian Journal of Chemistry 36, no. 12 (2024): 2855–60. https://doi.org/10.14233/ajchem.2024.32708.

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In current study, five new compounds containing thiazolyl-thiazolidinone conjugated substituted pyrazoles were prepared and screened for anticancer and antimicrobial activities. Synthesized compounds were characterized by spectroscopic techniques. Anticancer activity was carried out against human melanoma cancer A375 and human breast cancer MDA-MB-231 cell lines. Also, these were screened for antibacterial activity against two Gram-positive Staphylococcus aureus, Bacillus subtilis strains and three Gram-negative Pseudomonas aeruginosa, Klebsiella pneumonia and Escherichia coli strains. Antican

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Omar, Ashraf M., Heba A. Abd El Razik, Aly A. Hazzaa, et al. "New pyrimidines and triazolopyrimidines as antiproliferative and antioxidants with cyclooxygenase-1/2 inhibitory potential." Future Medicinal Chemistry 11, no. 13 (2019): 1583–603. http://dx.doi.org/10.4155/fmc-2018-0285.

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Aim: Cyclooxygenase-2 (COX-2) inhibition and scavenging-free radicals are important targets in cancer treatment. Materials & methods: Sulfanylpyrimidines and triazolopyrimidines were synthesized and evaluated as anticancer and antioxidant COX-1/2 inhibitors. Results: Compound 7 showed the same growth inhibitory activity as 5-fluorouracil against MCF-7. Compound 6f displayed broad-spectrum anticancer activity against the four tested cancer cell lines. Compounds 5b, 6a, 6c, 6d and 8 were found to be more active antioxidants than trolox. Compounds 6a, 6c, 6f and 8 revealed high COX-2 inhibito

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Guan, Yong-Feng, Xiu-Juan Liu, Xin-Ying Yuan, et al. "Design, Synthesis, and Anticancer Activity Studies of Novel Quinoline-Chalcone Derivatives." Molecules 26, no. 16 (2021): 4899. http://dx.doi.org/10.3390/molecules26164899.

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The chalcone and quinoline scaffolds are frequently utilized to design novel anticancer agents. As the continuation of our work on effective anticancer agents, we assumed that linking chalcone fragment to the quinoline scaffold through the principle of molecular hybridization strategy could produce novel compounds with potential anticancer activity. Therefore, quinoline-chalcone derivatives were designed and synthesized, and we explored their antiproliferative activity against MGC-803, HCT-116, and MCF-7 cells. Among these compounds, compound 12e exhibited a most excellent inhibitory potency a

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Huang, Jiuhong, Juanli Wang, Guiting Song, et al. "Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in Colorectal Cancer Cell." Molecules 27, no. 24 (2022): 8844. http://dx.doi.org/10.3390/molecules27248844.

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Colorectal cancer (CRC) is one of the most common causes of cancer-related death worldwide, and more therapies are needed to treat CRC. To discover novel CRC chemotherapeutic molecules, we used a series of previously synthesized novel imidazolidin-4-one derivatives to study their anticancer role in several cancer cell lines. Among these compounds, compound 9r exhibited the best anticancer activity in CRC cell lines HCT116 and SW620. We further investigated the anticancer molecular mechanism of compound 9r. We found that compound 9r induced mitochondrial pathway apoptosis in HCT116 and SW620 ce

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Dissertations / Theses on the topic "Anticancer compound"

1

McGinley, Susan. "A New Anticancer Compound from an Ancient Plant." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2010. http://hdl.handle.net/10150/622060.

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Rivero-MuÌˆller, Adolfo. "Speciation and reactivity of the antineoplastic copper-based compound : casiopeina II." Thesis, University of Surrey, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301319.

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Rothmeier, Andrea. "Anticancer effects and antiangiogenic mechanisms of the marine compound spongistatin 1." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-93090.

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Rothmeier, Andrea Silvia. "Anticancer effects and antiangiogenic mechanisms of the marine compound spongistatin 1." kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/9309/.

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Pouliwe, Antibe. "Electrochemical Studies of The Interaction Between DNA and a Compound Having Anticancer Properties." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/1352.

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Electrochemical method has been used to study the interaction between DNA and the compound N-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-N'-(2-imidazoyl)urea having anticancer properties. A DNA modified nanometer-sized gold electrode was prepared by surface modification of a bare gold electrode using cysteamine. These electrodes have been characterized using electrochemical techniques and were used to study the interaction between DNA and the compound. Our results showed an increase in the adsorption peak current and a negative shift of E1/2 in the oxidation of ferroc

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Bertuzzi, Giulio. "Synthesis and functionalization of a lactam-pyrazole molecular scaffold as a promising anticancer compound." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/9035/.

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The importance of pyrazole and lactam-based molecules in medical and pharmaceutical fields is underlined by the multitude of active ingredients on trade, such as Sildenafil or Apixaban, by Pfizer. In this work, a synthesis of an organic molecule with promising anticancer activity has been developed. This molecular scaffold is characterized by a δ-lactam-fused pyrazolic core, with a well-known biological activity and amenable of further functionalization. The synthetic strategy adopted for the obtainment of the core was based on a 1,3-dipolar cycloaddition of a nitrilimine with an α,β-unsaturat

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De, Vizcaya Ruiz Andrea M. G. "Distribution, toxicity and mode of action of the novel copper-based anticancer compound, casiopeina II." Thesis, University of Surrey, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310720.

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Kamasah, Alexander. "Using Electrochemical Method to Study the Interaction Between DNA and a compound Known to Have Anticancer Property." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/1379.

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The interaction of 4-(1'-[8'-(1''-pyrenyl)naphthyl])-2,6-diaminopyridine bis-glycamide bishydrocholride known to have anticancer properties with deoxyribonucleic acid (DNA) had been studied on a modified gold electrode by self-assembled monolayer using cyclic voltammetry. K4Fe (CN)6 was used as a probe to obtain electrochemical information on the electrode surface. A bare gold (Au) electrode was modified with cysteamine and our results showed no change in the limiting steady state current as compared to the bare Au electrode. There was a reduction in the steady state current after the modifica

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Vidimar, V. "Characterization of the anticancer properties of ruthenium-derived compounds: mode of action, optimization and development of experimental tools." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3423354.

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Platinum-based compounds are widely used anticancer drugs, despite severe side effects and drug-resistance phenomena. Over the past few years, a new class of platinum-free metal-based compounds, called RDCs (ruthenium-derived compounds), has been introduced with the aim of overcoming these issues. RDCs, in particular RDC11, have shown interesting and peculiar biological properties: a good anticancer activity in vivo, a reduced toxicity on healthy tissues and the ability to induce apoptosis through the induction of the CHOP/DDIT3 protein via a DNA-independent mechanism. Indeed, in contrast to p

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Brustolin, Leonardo. "Novel antiblastic Ru(III)-, Cu(II)- and Au(III)-based coordination compounds: from rational design, synthesis and physico-chemical characterization to nanoformulation, targeted delivery and in vitro evaluation." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3425843.

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There is an essential contribution of inorganic medicinal chemistry in the pharmacopeia. In particular, platinum-based drugs revolutionized the anticancer chemotherapy, and nowadays they find wide application in the treatment of several solid tumors. Nevertheless, their effectiveness is paralleled with severe side-toxicity and the onset of drug resistance. In order to obtain compounds with a better chemotherapeutic index and increased bioavailability, several metal-based compounds have been designed and investigated in the last decades. On these grounds, we present here the synthesis and chara

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Books on the topic "Anticancer compound"

1

Subarnas, Anas. Identification of novel anticancer compounds from primates-consumed plant: Final report. Kementerian Pendidikan Nasional, 2010.

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Subarnas, Anas. Identification of novel anticancer compounds from primates-consumed plant: Final report. Kementerian Pendidikan Nasional, 2010.

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Gurgi, Mohamedkamal Ahmed. ESI-MS[n] of anticancer pt[iv] organoamido complexes and their interactions with DNA-model compounds. Brock University, Department of Chemistry, 2001.

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4

Sǣngkhǣ, Čhantharawan. Konlayut nai kānkhonphop sān tān mareng chanit mai čhāk sārāi thalē læ/rư̄ yā thalē nai thǣp chāifang thalē Phāk Tawanʻō̜k khō̜ng Prathēt Thai: Strategies for the discovery of new anticancer compounds from seaweeds and/or seagrasses in the east coast of the gulf of Thailand. Mahāwitthayālai Buraphā, 2008.

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Singh, Rajesh Kumar, ed. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/97898150400741220101.

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This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decis

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Roffey, Jonathan Richard Anthony. The synthesis of indole containing anticancer compounds. 1996.

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Atta-ur-Rahman and Khurshid Zaman, eds. Topics in Anti-Cancer Research: Volume 8. BENTHAM SCIENCE PUBLISHERS, 2019. http://dx.doi.org/10.2174/97898114043821190801.

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Topics in Anti-Cancer Research covers new developments in the field of cancer. Novel drugs as anticancer agents include natural and synthetic phenazines and other anti-cancer compounds. It also encompasses the role of estrogen as endocrine disruptors and strategies targeting cancer stem cells for the treatment of different types of cancers, including myeloma and renal cell cancer. The diversity of researches and topics published in this eBook Series will be valuable to cancer researchers, clinicians, and cancer professionals aiming to develop novel anti-cancer targets for the treatment of vari

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Payne, Emma Kate. The synthesis and characterization of novel platinum and palladium diimene compounds for use as anticancer drugs and CO2 reduction catalyst. 2003.

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Vairappan, Charles S. Ecological Chemicals as Ecosystem Function Mediaters and Potential Lead Pharmaceuticals. UMS Press, 2021. http://dx.doi.org/10.51200/ecologicalchemicalsumspress2021-978-967-2962-94-6.

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Relationship between functioning ecosystem services and human wellbeing has been established as a bridge connecting nature and society. It has also become central pillar of sustainability science and dictates the paradigms of sustainable development. But, conceptual frameworks that systematically integrates the important roles played by natural ecological chemicals by establishing empirical links between the nature and ecology not only varies, but lacks clear support. The value of ecological chemicals as ecosystem derived natural products warrants explicit acknowledgement, only then trade-offs

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Book chapters on the topic "Anticancer compound"

1

Vater, Carol A., and Victor S. Goldmacher. "Antibody–Cytotoxic Compound Conjugates for Oncology." In Macromolecular Anticancer Therapeutics. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-0507-9_9.

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Nakajima, Kenji. "Amelioration Effect of a Tertiary Sulfonium Compound, Dimethylsulfoniopropionate, in Green Sea Algae on Ehrlich Ascitic-tumor, Solid Tumor and Related Diseases." In Handbook of Anticancer Drugs from Marine Origin. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07145-9_11.

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Lata, Hemant, Cassia S. Mizuno, and Rita M. Moraes. "The Role of Biotechnology in the Production of the Anticancer Compound Podophyllotox." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-287-2_31.

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Abakay, Abdurrahman. "Effects of Turmeric in Neurological Diseases." In Neurological Diseases and Treatments in Terms of Biochemistry. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359357.7.

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Zingiberaceae is a large and diverse family of plants commonly known as the “Gingeraceae”. The Zingiberaceae family is a plant family known for its plant diversity, economic importance, and potential for medicinal use. Turmeric is a perennial, rhizomatous, herbaceous plant from the ginger family, containing the compound curcumin and offering many health benefits Cardamom, turmeric, and ginger are among the bioactive chemicals having antioxidant action that belong to the Zingiberaceae family. In addition, they possess anti-inflammatory, antibacterial, anticancer, and antiemetic characteristics,

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Prakash, Om, and Feroz Khan. "CoSSDb: A Database of Co-crystallized Ligand Sub-structures for Anticancer Lead Designing & Optimization." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_14.

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AbstractThe Discovery of the novel optimized structures of small molecules for selective targeting is one of the challenging tasks in drug designing. Bioisosteres are the key components of the lead compound, which provide hidden power to the compound scaffold for selective targeting. We are presenting a database, named CoSSDb which stands for Co-crystallized Sub-Structure Database. The CoSSDb contains ligand sub-structures as possible bioisosteres. extracted from PDB files, available in Protein Data Bank. Sub-structures were extracted through an algorithm, which utilizes the location of atoms

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Breslow, Ronald. "From DMSO to the Anticancer Compound SAHA, an Unusual Intellectual Pathway for Drug Design." In Successful Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527800315.ch1.

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Plunger, Bryan, Chang Kyoung Choi, and Tim E. Sparer. "Electrical Cell-Substrate Impedance Sensing for Measuring Cellular Transformation, Migration, Invasion, and Anticancer Compound Screening." In Electric Cell-Substrate Impedance Sensing and Cancer Metastasis. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-4927-6_4.

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Wetterauer, B., E. Wildi, and M. Wink. "Production of the Anticancer Compound Camptothecin in Root and Hairy Root Cultures of Ophiorrhiza mungos L." In Biotechnological Approaches for Medicinal and Aromatic Plants. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-0535-1_14.

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Saeidnia, Soodabeh. "Marine-Derived Anticancer Compounds." In New Approaches to Natural Anticancer Drugs. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-14027-8_3.

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My, Vo Thi Ngoc, and Nguyen Van Thanh. "Determination of Structure and Anticancer Activity of MM1 Compound Isolated from Endophytic Fungus Aspergillus terreus-RTN3 of Alpinia chinensis Rosc." In IFMBE Proceedings. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-75506-5_51.

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Conference papers on the topic "Anticancer compound"

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Subhashree, A., and G. Puthilibai. "Sustainable Mechanistic Insights into the Anticancer and Antimicrobial Activities of Ruthenium and Palladium Compounds." In 2024 International Conference on Power, Energy, Control and Transmission Systems (ICPECTS). IEEE, 2024. https://doi.org/10.1109/icpects62210.2024.10780410.

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Zbancioc, Gheorghita, Costel Moldoveanu, and Ionel I. Mangalagiu. "Syntheses of new benzoquinoline derivatives with anticancer activity." In Conferința științifică națională cu participare internațională "Integrare prin cercetare și inovare", dedicată Zilei Internaționale a Științei pentru Pace și Dezvoltare. Moldova State University, 2025. https://doi.org/10.59295/spd2024n.92.

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This work synthesized various novel benzo[c]quinoline compounds, detailed their structural features, and examined their anticancer activity in vitro. First, the nitrogen atom in benzo[c]quinoline is quaternized, and the in situ-formed ylide is then subjected to a [3+2] dipolar cycloaddition reaction. A detailed investigation was conducted to determine how successful traditional thermal heating (TH) synthesis was in comparison to microwave (MW) and ultrasonic (US) irradiation. FTIR, HRMS, and NMR were the three spectral techniques that were used to prove the structure of all the obtained compou

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Ungur, Nicon, Aurelian Gulea, and Tatiana Erhan. "Synthesis and study of the same hydrazincarbothioamides as privilege pharmacophores in pharmacology." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab05.

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Hydrazinecarbothioamides represent a privileged class of pharmacophores in pharmacology, thanks to an impressive number of derivatives that exhibit outstanding antimicrobial, anticancer and antifungal properties [1]. The presence of electron donor atoms such as N(nitrogen) and S(sulfur) substantially widen the spectrum of use. In the framework of theoretical studies on the structure of biologically active compounds with valuable properties were highlighted following common structural elements such as substitution of a hydrogen atom from the nitrogen atom (N) with the benzene ring, the introduc

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Braig, Friederike, Jordan U. Gutterman, and Diego Acosta-Alvear. "Abstract 1033: The anticancer compound avicin D targets lysosomal functions." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1033.

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Chen, Yih-wen, Jang-yang Chang, and Kai-Ming Chou. "Abstract 3813: DNA polymerase eta and a novel anticancer selenophene compound." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3813.

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Binanto, Iwan. "Improving of anticancer compound identification model for medicinal plant’s LCMS data." In THE 3RD INTERNATIONAL CONFERENCE ON NATURAL SCIENCES, MATHEMATICS, APPLICATIONS, RESEARCH, AND TECHNOLOGY (ICON-SMART2022): Mathematical Physics and Biotechnology for Education, Energy Efficiency, and Marine Industries. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0201202.

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Jovičić Milić, Sandra S., Marko Antonijević, Đorđe S. Petrović, Verica V. Jevtić, and Danijela Lj Stojković. "Investigation of the anticancer activity of 2-amino-6-methylbenzothiazole and corresponding Pd(II) complex using molecular docking simulations." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.535jm.

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In our prior investigations, it has been established that compound di(2-amino-6-methylbenzothiazole)dichloridopalladate(II) (C1) exhibits promising efficacy in inhibiting the growth of colon carcinoma, thereby demonstrating potential as an anticancer agent. To elucidate the underlying mechanism of action against cancer, a comprehensive investigation involving DNA binding analysis and a series of assays to evaluate the inhibitory potential of compound C1 against key proteins involved in cancer metabolism were conducted. The significant inhibitory potential of C1 towards Bcl-2, Ki-67, and CDK-4

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Syahri, Jufrizal, Rahmadini Syafri, Hasmalina Nasution, Della Pratiwi, Emmy Yuanita, and Beta Achromi Nurohmah. "Design of 2-Phenylamino Benzothiopyrano [4,3-D] Pyrimidines Compound as an Anticancer." In Proceedings of the International Conference of CELSciTech 2019 - Science and Technology track (ICCELST-ST 2019). Atlantis Press, 2019. http://dx.doi.org/10.2991/iccelst-st-19.2019.14.

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Carvalho, Filipa G., Maryam Abbasi, Bernardete Ribeiro, and Joel P. Arrais. "Deep Model for Anticancer Drug Response through Genomic Profiles and Compound Structures." In 2022 IEEE 35th International Symposium on Computer-Based Medical Systems (CBMS). IEEE, 2022. http://dx.doi.org/10.1109/cbms55023.2022.00050.

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Kosanović, Marta, Thomas Eichhorn, Dejan Milenković, Goran Kaluđerović, Jasmina Dimitrić Marković, and Dušan Dimić. "Synthesis, spectroscopic, and quantum-chemical analysis of mononuclear Ru(II)-naphthylhydrazine complex." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.391k.

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Ruthenium(II) complexes have become increasingly recognized and utilized as potent anticancer agents in recent years. These compounds possess unique capabilities in targeting cancer cells and interfering with vital cellular processes, offering new hope in the relentless battle against cancer. This research study focuses on the characterization of a newly synthesized Ru(II)-naphthylhydrazine complex by IR and NMR spectroscopies. NMR spectral data have revealed the presence of different chemical environments within 1 based on the chemical shifts observed in the 1H and 13C NMR spectra. The infrar

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Reports on the topic "Anticancer compound"

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Annunziato, Dominick. HPLC Sample Prep and Extraction SOP v1.3 for Fungi. MagicMyco, 2023. http://dx.doi.org/10.61073/sopv1.3.08.11.2023.

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medicine, industry, and biotechnology. Fungi produce a wide range of bioactive compounds, such as alkaloids, antibiotics, antifungals, immunomodulators, anticancer agents, enzymes, and vitamins. However, these compounds are often locked inside the fungal cell wall, which is composed of chitin, a tough substance that is dif�icult to digest by humans1. Therefore, it is essential to have a good extraction technique that can break down the chitin and release the valuable compounds from the fungi, this is especially essential in the laboratory for accurate lab assays and potency determination durin

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Chaudhuri, Gautam. Enhancement of the Efficacy of Conventional Anticancer Compounds through the Repression of SNAI Proteins in Aggressive Breast Cancer Cells. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada572979.

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Venedicto, Melissa, and Cheng-Yu Lai. Facilitated Release of Doxorubicin from Biodegradable Mesoporous Silica Nanoparticles. Florida International University, 2021. http://dx.doi.org/10.25148/mmeurs.009774.

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Cervical cancer is one of the most common causes of cancer death for women in the United States. The current treatment with chemotherapy drugs has significant side effects and may cause harm to healthy cells rather than cancer cells. In order to combat the potential side effects, nanoparticles composed of mesoporous silica were created to house the chemotherapy drug doxorubicin (DOX). The silica network contains the drug, and a pH study was conducted to determine the conditions for the nanoparticle to disperse the drug. The introduction of disulfide bonds within the nanoparticle created a fram

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Chen, Xiaole, Peng Wang, Yunquan Luo, et al. Therapeutic Efficacy Evaluation and Underlying Mechanisms Prediction of Jianpi Liqi Decoction for Hepatocellular Carcinoma. Science Repository, 2021. http://dx.doi.org/10.31487/j.jso.2021.02.04.sup.

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Objective: The aim of this study was to assess the therapeutic effects of Jianpi Liqi decoction (JPLQD) in hepatocellular carcinoma (HCC) and explore its underlying mechanisms. Methods: The characteristics and outcomes of HCC patients with intermediate stage B who underwent sequential conventional transcatheter arterial chemoembolization (cTACE) and radiofrequency ablation (RFA) only or in conjunction with JPLQD were analysed retrospectively. The plasma proteins were screened using label-free quantitative proteomics analysis. The effective mechanisms of JPLQD were predicted through network pha

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