Relevant bibliographies by topics / Anticancer Secondary Metabolites

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Anticancer Secondary Metabolites'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 September 2023

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Journal articles on the topic "Anticancer Secondary Metabolites"

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Uras, İbrahim Seyda, and Belma Konuklugil. "Anticancer secondary metabolites from marine sponges." Ege Journal of Fisheries and Aquatic Sciences 38, no. 1 (2021): 101–6. http://dx.doi.org/10.12714/egejfas.38.1.12.

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The oceans cover 70% of the Earth’s surface. The marine environment is an important source of secondary metabolites with high biodiversity. Besides other marine species, sponges with a wide range of secondary metabolites are an important potential for drug discovery. Cancer is one of the leading causes of death with high morbidity and mortality. It is very important to discover new therapeutic agents in the treatment of cancer. In recent years, studies on exploring new anticancer compounds are focused on the marine source. In this review, our target is collecting the studies about marine spong
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Solárová, Zuzana, Alena Liskova, Marek Samec, Peter Kubatka, Dietrich Büsselberg, and Peter Solár. "Anticancer Potential of Lichens’ Secondary Metabolites." Biomolecules 10, no. 1 (2020): 87. http://dx.doi.org/10.3390/biom10010087.

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Lichens produce different classes of phenolic compounds, including anthraquinones, xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed effective biological activities such as antioxidant, antiviral, antibiotics, antifungal, and anticancer. Although no clinical study has been conducted yet, there are number of in vitro and in vivo studies demonstrating anticancer effects of lichen metabolites. The main goal of our work was to review most recent published papers dealing with anticancer activities of secondary metabolites of lichens and point out to their perspective cl
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Evidente, Antonio, Alexander Kornienko, Alessio Cimmino, et al. "Fungal metabolites with anticancer activity." Nat. Prod. Rep. 31, no. 5 (2014): 617–27. http://dx.doi.org/10.1039/c3np70078j.

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Simko, Patrik, and Terezia Kiskova. "Uncovering the Anticancer Potential of Lichen Secondary Metabolites." Journal of Analytical Oncology 11 (December 14, 2022): 70–78. http://dx.doi.org/10.30683/1927-7229.2022.11.10.

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Lichens produce a plethora of primary and secondary metabolites. Secondary metabolites have several biological functions that can be used for human health. Recent studies have described their antioxidant, anti-inflammatory, antimycotic, and antibiotic/antiviral activities. However, attention has mainly been focused on their antiproliferative, cytotoxic, and anticancer effects. Because there are many publications describing the molecular mechanisms leading to the anticancer effects of lichen secondary metabolites, the aim of this review is to summarize results from current research with the mai
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Mohammadi, Mehdi, Moj Khaleghi, Shahriyar Shakeri, Majid Askari Hesni, Mohammad Rasoul Samandari-Bahraseman, and Ava Dalvand. "Isolation of Actinobacteria Strains From Environmental Samples and Assessment of Their Bioactivity." Avicenna Journal of Clinical Microbiology and Infection 9, no. 1 (2022): 18–25. http://dx.doi.org/10.34172/ajcmi.2022.03.

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Background: Actinobacteria are widespread and live in a variety of habitats. Today, these bacteria are very important due to the production of various secondary metabolites with different biological activities. The present study aimed to isolate strains of Actinobacteria from different habitats (the Persian Gulf, Gandom Beryan area in the Lut Desert, and some plant roots). The anticancer and antimicrobial activities of secondary metabolites of these isolates were also investigated. Methods: Samples were taken from water of the Persian Gulf, soil of Gandom Beryan area in the Lut Desert, and pla
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Sevastre, Ani-Simona, Elena Victoria Manea, Oana Stefana Popescu, et al. "Intracellular Pathways and Mechanisms of Colored Secondary Metabolites in Cancer Therapy." International Journal of Molecular Sciences 23, no. 17 (2022): 9943. http://dx.doi.org/10.3390/ijms23179943.

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Despite the great advancements made in cancer treatment, there are still many unsatisfied aspects, such as the wide palette of side effects and the drug resistance. There is an obvious increasing scientific attention towards nature and what it can offer the human race. Natural products can be used to treat many diseases, of which some plant products are currently used to treat cancer. Plants produce secondary metabolites for their signaling mechanisms and natural defense. A variety of plant-derived products have shown promising anticancer properties in vitro and in vivo. Rather than recreating
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Pham, Van Thuy Thi, Chung Thanh Nguyen, Dipesh Dhakal, Hue Thi Nguyen, Tae-Su Kim, and Jae Kyung Sohng. "Recent Advances in the Heterologous Biosynthesis of Natural Products from Streptomyces." Applied Sciences 11, no. 4 (2021): 1851. http://dx.doi.org/10.3390/app11041851.

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Streptomyces is a significant source of natural products that are used as therapeutic antibiotics, anticancer and antitumor agents, pesticides, and dyes. Recently, with the advances in metabolite analysis, many new secondary metabolites have been characterized. Moreover, genome mining approaches demonstrate that many silent and cryptic biosynthetic gene clusters (BGCs) and many secondary metabolites are produced in very low amounts under laboratory conditions. One strain many compounds (OSMAC), overexpression/deletion of regulatory genes, ribosome engineering, and promoter replacement have bee
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Udayan, E., and Joel J. Gnanadoss. "Potential of endophytic fungi as therapeutics: Antibiotics, Antiviral and Anticancer properties." Research Journal of Biotechnology 18, no. 6 (2023): 132–45. http://dx.doi.org/10.25303/1806rjbt1320145.

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Antibiotic resistance, an emerging threat to human health, is the world's major challenge today. Endophytic microbes found in medicinal plants aid in the resolution of these issues. It is critical to select the plant that will be used to investigate endophytes for bioactive metabolites. As a result, medicinal plants which have been used as a traditional source of medicine for centuries, are a valuable source for bioprospecting endophytes. Fungi are the most commonly reported organisms among endophytes. Endophytic fungi are a diverse group of microbes that invade plant interior tissues without
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Sugita, Purwantiningsih, Dina Anggraini, Gustini Syahbirin, Dyah Utami Cahayaning Rahayu, and Auliya Ilmiawati. "Secondary Metabolites from Indonesian Kigelia africana (Bignoniaceae)." Journal of the Indonesian Chemical Society 2, no. 2 (2019): 114. http://dx.doi.org/10.34311/jics.2019.02.2.114.

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From the fruit of Kigelia africana three fractions of secondary metabolites were isolated. Fraction 1 (CD-1) was characterized by using UV-Vis, FTIR, 1D and 2D NMR and MS, meanwhile fraction 2 (CD-2) and 3 (B-1) were characterized by LCMS and compared with literature. All these fractions were screened for anticancer activity by using (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method to calculate IC50 toward Michigan Cancer Foundation-7 MCF-7 breast cancer and menogaril-resistant mouse leukemia P388 cells. Based on spectroscopic data, CD-1 fraction was identified as me
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Maya Dian Rakhmawatie, Maya Dian Rakhmawatie, Mustofa Mustofa, Puspita Lisdiyanti Puspita Lisdiyanti, Woro Rukmi Pratiwi Woro Rukmi Pratiwi, and Tri Wibawa Tri Wibawa. "Identification of Antimycobacterial from Actinobacteria (INACC A758) Secondary Metabolites using Metabolomics Data." Sains Malaysiana 51, no. 5 (2022): 1465–73. http://dx.doi.org/10.17576/jsm-2022-5105-16.

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Actinobacteria produce active secondary metabolite with medicinal properties, such as antibacterial or anticancer. However, there are some reports about the difficulties in discovering novel secondary metabolites. Therefore, the need for a new approach is obvious. Several factors such as types of nutrients in the culture media or different solvents used for extraction have been proven to influence the Actinobacteria secondary metabolite production. In this study, a combination of culture media optimization and metabolites fingerprint analysis were applied to identify antimycobacterial active c
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Dissertations / Theses on the topic "Anticancer Secondary Metabolites"

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Boonlarppradab, Chollaratt. "Investigation of the potential anticancer and antifungal active secondary metabolites from marine natural products." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3274752.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed October 5, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Turbyville, Thomas Jefferson. "Using Phylogenetically Conserved Stress Responses to Discover Natural Products with Anticancer Activity." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1078%5F1%5Fm.pdf&type=application/pdf.

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Shrestha, Gajendra. "Exploring the Antibacterial, Antioxidant, and AnticancerProperties of Lichen Metabolites." BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/4393.

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Natural products have been a significant source of new drugs, especially in treating cancer, infectious diseases, hypertension, and neurological disorders. Although many natural metabolites have been screened and yielded pharmaceutically important drugs, many potential sources of natural product drug therapies still need to be investigated, including lichens. Lichens are symbiotic systems consisting of a filamentous fungus and a photosynthetic partner (an eukaryotic alga and/or cyanobacterium). Lichens produce an impressive variety of unique secondary compounds and have been used as ingredient
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Benatrehina, Paule Annecie. "Identification and Isolation of Secondary Metabolites from Podocarpus neriifolius Using Bioactivity-Guided and 1D-NMR-Based Dereplication Approaches." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu153193675651081.

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Tan, Choon Yong. "Identification and Dereplication of Bioactive Secondary metabolites of Penicillium aurantiacobrunneum, a Fungal Associate of the Lichen Niebla homalea." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586533114478772.

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Geethanjali, D. "New Anticancer Secondary Metabolites from an Endophytic Fungus Chaetomium Nigricolor Isolated from Catharanthus Roseus : Structural Elucidation and Molecular Mechanism Underlying Anticancer Effects." Thesis, 2017. http://etd.iisc.ac.in/handle/2005/3697.

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Cancer has become a major health problem due to its high rate of morbidity and mortality. Severe side effects associated with most of the available anticancer drugs and the development of the drug resistant cells are the major hurdles limiting their application and therapeutic success. Much attention has thus been focused on natural compounds with minimal or no toxicity in humans and having capacity to suppress proliferation and/or induce apoptosis in cancer cells. Therefore, it is imperative to discover and develop new anticancer drugs. Endophytic fungi though underexploited have remained a r
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Geethanjali, D. "New Anticancer Secondary Metabolites from an Endophytic Fungus Chaetomium Nigricolor Isolated from Catharanthus Roseus : Structural Elucidation and Molecular Mechanism Underlying Anticancer Effects." Thesis, 2017. http://etd.iisc.ernet.in/2005/3697.

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Cancer has become a major health problem due to its high rate of morbidity and mortality. Severe side effects associated with most of the available anticancer drugs and the development of the drug resistant cells are the major hurdles limiting their application and therapeutic success. Much attention has thus been focused on natural compounds with minimal or no toxicity in humans and having capacity to suppress proliferation and/or induce apoptosis in cancer cells. Therefore, it is imperative to discover and develop new anticancer drugs. Endophytic fungi though underexploited have remained a r
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Taritla, Sidhartha. "Isolation, structure elucidation and increasing anticancer efficacy of an anti-cancer secondary metabolite from a marine-derived endophytic fungus, Aspergillus species." Thesis, 2023. https://etd.iisc.ac.in/handle/2005/6149.

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Cancer is the leading cause of mortality globally, contributing to ~10 million fatalities in 2020, or roughly one in every six deaths, according to global cancer statistics 2020. Around 50% of all small molecules approved for treatment of cancer between the 1940s and the end of 2014 are comprised of either naturally occurring substances or compounds that were synthesized using those substances. The majority of bioactive chemicals are obtained from terrestrial microorganisms, and while the terrestrial environment is abundant in bioactive producers, the finding of new metabolites is withering. M
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Kamat, Siya. "Investigation of anticancer compounds in the natural productome of marine algae associated-endophytic fungi." Thesis, 2022. https://etd.iisc.ac.in/handle/2005/6032.

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Cancer is one of the leading causes of death worldwide. Owing to the complex ways in which this disease develops, there is a constant demand for new drugs. Natural products have delivered great promise in inspiring chemotherapy, for example, Taxol, Trabectedin, Plinabulin, Marizomib, Midostaurin, etc. Endophytic fungi have potentiated this promise by producing potent bioactive compounds. They live symbiotically in the internal tissues of higher organisms. Marine endophytic fungi offer a diverse chemical space for the discovery of novel anticancer compounds, sustainably. Marine endophytes demon
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Lin, Cheng-Pan, and 林振邦. "Study on the Mechanisms of Anticancer Activity of a Fungal Secondary Metabolite, Cephalochromin, in Nasopharyngeal Carcinoma Cells." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/80668015121706916992.

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碩士<br>中國醫藥大學<br>藥學系碩士班<br>97<br>According to the recently information release from the Department of Health, the malignant tumor is the number 1 cause of death in Taiwan for the last 27 years. Although, several great improvement have been established for treating cancer, developing the drug resistance by the cancer cells causes the curative effect generally not good. Therefore, the new antitumor medicine''s research and development appear urgent. At present the source of antitumor agents is major isolated or derivatives from the plant or the animal, but recently, several studies demonstrated t
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Books on the topic "Anticancer Secondary Metabolites"

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Vairappan, Charles S. Ecological Chemicals as Ecosystem Function Mediaters and Potential Lead Pharmaceuticals. UMS Press, 2021. http://dx.doi.org/10.51200/ecologicalchemicalsumspress2021-978-967-2962-94-6.

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Relationship between functioning ecosystem services and human wellbeing has been established as a bridge connecting nature and society. It has also become central pillar of sustainability science and dictates the paradigms of sustainable development. But, conceptual frameworks that systematically integrates the important roles played by natural ecological chemicals by establishing empirical links between the nature and ecology not only varies, but lacks clear support. The value of ecological chemicals as ecosystem derived natural products warrants explicit acknowledgement, only then trade-offs
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Book chapters on the topic "Anticancer Secondary Metabolites"

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Stanojković, Tatjana. "Investigations of Lichen Secondary Metabolites with Potential Anticancer Activity." In Lichen Secondary Metabolites. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-13374-4_5.

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Stanojković, Tatjana. "Investigations of Lichen Secondary Metabolites with Potential Anticancer Activity." In Lichen Secondary Metabolites. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16814-8_5.

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Kaur, Jeevanjot, Sonia Mahey, Pankaj Ahluwalia, Rakesh Joshi, and Rakesh Kumar. "Role of Plant Secondary Metabolites as Anticancer and Chemopreventive Agents." In Plant Secondary Metabolites. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-4779-6_4.

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Milutinović, Milena, and Danijela Cvetković. "Anticancer Activity of Secondary Metabolites of Teucrium Species." In Teucrium Species: Biology and Applications. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-52159-2_13.

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Wu, Ching-Fen, and Thomas Efferth. "Anticancer Activity of Salvia miltiorrhiza and Its Secondary Metabolites." In Salvia Biotechnology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-73900-7_5.

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Scotti, Luciana, Nagendra Sastry Yarla, Francisco J. B. Mendonça Filho, et al. "CADD Studies Applied to Secondary Metabolites in the Anticancer Drug Research." In Anticancer Plants: Mechanisms and Molecular Interactions. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8417-1_9.

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Selvakesavan, Rajendran K., Dariusz Kruszka, Preeti Shakya, Dibyendu Mondal, and Gregory Franklin. "Impact of Nanomaterials on Plant Secondary Metabolism." In Nanomaterial Interactions with Plant Cellular Mechanisms and Macromolecules and Agricultural Implications. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-20878-2_6.

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AbstractPlants encounter various nanomaterials (NMs) as pesticides and fertilizers. It is also possible that nanomaterials reach plants as waste from consumer products and industry. The effects of such NMs on plants have been widely studied, and both positive and negative effects of NMs on plant growth and development have been reported. Recent metabolomics studies suggest that nanoparticles affect the concentration of secondary metabolites in plants by modulating reactive nitrogen/oxygen species, gene expression, and signaling pathways. Secondary metabolites are plant compounds that accumulate in plants through their secondary metabolism. To date, more than 200,000 defined structures of secondary metabolites have been identified, among which many of them possess antibacterial, antifungal, antiviral, anti-inflammatory, hepatoprotective, antidepressant, antioxidant, neuroprotective, and anticancer properties. The application of elicitors is a simple strategy to increase the production of secondary metabolites in plant cell and tissues. The ability of nanomaterials to induce plant secondary metabolism has recently been exploited in the elicitation of pharmaceutically important compounds from various plant species. The ability of different NMs to induce the accumulation of different classes of compounds in the same plant species has also been accomplished. The molecular mechanisms behind the effects of NMs on plant secondary metabolism revealed the putative genes involved in NM-mediated elicitation of various plant compounds in several reports. This chapter reviews the current understanding of the effects of nanoparticles on plant secondary metabolism and the elicitation of pharmacologically important compounds from plant species.
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Siddiqui, Zahid H., B. Hareramdas, Zahid K. Abbas, Talat Parween, and Mohammad Nasir Khan. "Use of Plant Secondary Metabolites as Nutraceuticals for Treatment and Management of Cancer: Approaches and Challenges." In Anticancer plants: Properties and Application. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8548-2_17.

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Contigli, Christiane, Elaine Maria de Souza-Fagundes, Warne Pedro de Andrade, Jacqueline Aparecida Takahashi, Yumi Oki, and G. Wilson Fernandes. "Perspectives of Baccharis Secondary Metabolites as Sources for New Anticancer Drug Candidates." In Baccharis. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83511-8_18.

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Nandi, Sudeshna, Rimpa Sikder, and Krishnendu Acharya. "Secondary Metabolites of Mushrooms: A Potential Source for Anticancer Therapeutics with Translational Opportunities." In Advancing Frontiers in Mycology & Mycotechnology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9349-5_23.

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Conference papers on the topic "Anticancer Secondary Metabolites"

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Alilou, M., J. Mottaghipisheh, T. Gelbrich, U. Peintner, J. Troppmair, and H. Stuppner. "Secondary metabolites of fungus Thyronectria sp. and their antifungal and anticancer activities." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759017.

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Gao, Jiayu, Ranran Cao, and Weiping Yin. "Chemical Informatic Investigation of Anticancer Secondary Metabolites from Spina Gleditsiae Using HPLC and NMR-based Techniques." In 2015 Seventh International Conference on Measuring Technology and Mechatronics Automation (ICMTMA). IEEE, 2015. http://dx.doi.org/10.1109/icmtma.2015.71.

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Popovici, Violeta, Laura Bucur, Gabriela Vochita, Victoria Badea, and Florin-Ciprian Badea. "CONTRIBUTIONS TO THE COMPLEX STUDY ON ANTITUMOR ACTIVITY OF USNEA BARBATA (L.) F.H.WIGG." In NORDSCI International Conference. SAIMA Consult Ltd, 2020. http://dx.doi.org/10.32008/nordsci2020/b1/v3/25.

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Usnea barbata (L.)F.H.Wigg. - known as “old man’s beard”, “tree moss”, “songluo” is a lichen in the family Parmeliaceae, genus Usnea. Usnea species have recorded history of therapeutic use dating back over three thousand years in Chinese medicine. The lichen secondary metabolites have shown an impressive range of biological proprieties, including antibiotic, antifungal, antiviral, anti-inflammatory, or anticancer activities. In this study, the antitumor activity of Usnea barbata extract was evaluated by observing the morphological changes on squamous cells carcinoma cell-line CAL 27 (ATCC® CRL
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Kuttikrishnan, Shilpa, Kirti S. Prabhu, Tamam Elimat, et al. "Anticancer Activity of Neosetophomone B, An Aquatic Fungal Secondary Metabolite, Against Hematological Malignancie S." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0106.

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Cancer is one of the most life threatening diseases, causing nearly 13% death in the worldwide. Leukemia, cancer of the hematopoetic cells is the main cause of cancer death in adults and children. Therapeutic agents used in treatment of cancer are known to have narrow therapeutic window and tendency to develop resistance against some cancer cell lines thus, proposing a need to discover some novel agents to treat cancer. In the present study we investigated the anticancer activity of Neosetophomone B(NSP-B), an aquatic fungal metabolite isolated from Neosetophoma sp against leukemic cells (K562
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