Relevant bibliographies by topics / Anticholinergic burden

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Anticholinergic burden'

Author: Grafiati
Published: 18 April 2022
Last updated: 30 July 2025

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Journal articles on the topic "Anticholinergic burden"

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Wilczyński, Krzysztof, Marta Gorczyca, Jagna Gołębiowska, and Jan Szewieczek. "Anticholinergic Burden of Geriatric Ward Inpatients." Medicina 57, no. 10 (2021): 1115. http://dx.doi.org/10.3390/medicina57101115.

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Background and Objectives: Anticholinergic drug use in the pharmacotherapy of elderly persons is common despite the increased risk of side effects. We examined the prevalence of anticholinergic drug use and total anticholinergic drug burden among patients admitted to an acute care geriatric ward in Poland. Materials and Methods: Cross-sectional study of 329 subjects hospitalized at the geriatric ward. Patient condition was assessed with a comprehensive geriatric assessment. The Anticholinergic Cognitive Burden (ACB) scale was used to estimate the total anticholinergic load. Results: Mean patie
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Chang, Wei Terk, and Shu Yi Lydia Au. "Anticholinergics in Older Adults- Avoid, Replace and Monitor." Singapore Family Physician 48, no. 5 (2022): 46–53. http://dx.doi.org/10.33591/sfp.48.5.uo1.

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Many medicines have varying degrees of anticholinergic activity. Some of these drugs, particularly those with intermediate or low activity, are not commonly known to possess anticholinergic properties. Regardless of their anticholinergic potency, when used concurrently, they could collectively contribute to the anticholinergic burden in elderly patients. While most of the adverse effects from the anticholinergic burden are reversible upon withdrawal of the anticholinergics, some of the adverse effects on the central nervous system (CNS) may be permanent. Fortunately, for most of the indication
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Krüger, Caroline, Ingmar Schäfer, Hendrik van den Bussche, et al. "Anticholinergic drug burden according to the anticholinergic drug scale and the German anticholinergic burden and their impact on cognitive function in multimorbid elderly German people: a multicentre observational study." BMJ Open 11, no. 3 (2021): e044230. http://dx.doi.org/10.1136/bmjopen-2020-044230.

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ObjectivesThe aims of our study were to examine the anticholinergic drug use and to assess the association between anticholinergic burden and cognitive function in the multimorbid elderly patients of the MultiCare cohort.SettingMultiCare was conducted as a longitudinal cohort study in primary care, located in eight different study centres in Germany.Participants3189 patients (59.3% female).Primary and secondary outcome measuresBaseline data were used for the following analyses. Drugs were classified according to the well-established anticholinergic drug scale (ADS) and the recently published G
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Akpan, Anietie, Bruno De Blaquiere, Issadevi Nellaya, Cornelia Termure, and Sujoy Mukherjee. "Polypharmacy and potentially inappropriate medications (PIMs) in older adults referred to a memory clinic." BJPsych Open 7, S1 (2021): S306. http://dx.doi.org/10.1192/bjo.2021.810.

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AimsThe older adult is more likely to be prescribed a lot of medications (polypharmacy) on account of multi-morbidity and consequently being under the care of several specialists. Adverse drug events and reactions account for significant morbidity and mortality in this population group. Common sequelae include confusional episodes, dementia syndromes, falls, and higher rates of acute hospital admissions.Medications are not routinely reviewed in elderly care. We sought to estimate the prevalence of polypharmacy, and potentially inappropriate medications (e.g. anticholinergics or medications wit
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Ulley, Joanna, Sakila Sickander, and Ahmed H. Abdelhafiz. "Polypharmacy and Anticholinergic Burden in Hospitalised Older Patients - A Cross Sectional Audit." International Journal of Biomedical Science 14, no. 1 (2018): 36–40. http://dx.doi.org/10.59566/ijbs.2018.14036.

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Objectives: To investigate the impact of hospital admission on polypharmacy and anticholinergic burden and explore doctors’ awareness of cognitive side effects of anticholinergics use. Methods:A cross sectional retrospective audit of older patients admitted to a care of elderly ward over three months. We have collected patients’ demographic data, number of medications and anticholinergic burden scale on admission compared to on discharge and investigated doctors’ knowledge about polypharmacy by answering a questionnaire. Results: 100 patients were included. Mean number of medications and antic
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Posis, Alexander Ivan B., Wassim Tarraf, Kevin A. Gonzalez, et al. "Anticholinergic Drug Burden and Neurocognitive Performance in the Study of Latinos-Investigation of Neurocognitive Aging." Journal of Alzheimer's Disease 86, no. 1 (2022): 53–65. http://dx.doi.org/10.3233/jad-215247.

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Background: Studies of cumulative anticholinergic drug burden on cognitive function and impairment are emerging, yet few for Hispanics/Latinos. Objective: To examine associations between anticholinergic use and neurocognitive performance outcomes among diverse Hispanics/Latinos. Methods: This prospective cohort study included diverse Hispanic/Latino participants, enrolled in the Study of Latinos-Investigation of Neurocognitive, from New York, Chicago, Miami, and San Diego (n = 6,249). Survey linear regression examined associations between anticholinergic use (measured during baseline [Visit 1]
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Yeo, Su Ying, Sanny Zi Lung Choo, Nadzirah Rosli, Eng Chong Koh, and Shyh Poh Teo. "144 Polypharmacy and Anticholinergic Burden in Older People in Brunei Darussalam." Age and Ageing 48, Supplement_4 (2019): iv34—iv39. http://dx.doi.org/10.1093/ageing/afz164.144.

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Abstract Introduction Polypharmacy and anticholinergic burden are associated with falls in older people. A longitudinal study found patients with five or more drugs had 21% increased falls over 2 years. [Dhalwani, Fahami, Sathanapally et al, BMJ Open, 2017,7(10), e016358]. A cohort study identified a 1.51 odds of recurrent falls with anticholinergic medication, while taking multiple anticholinergics resulted in 100% likelihood of recurrent falls. [Marcum, Wirtz, Pettinger, et al, BMC Geriatrics, 2016,16,76]. Methods Retrospective study of polypharmacy in older people in Brunei based on data fr
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Randall, J., A. Hook, C.-M. Grubb, et al. "Dementia patients have greater anti-cholinergic drug burden on discharge from hospital: A multicentre cross-sectional study." European Psychiatry 64, S1 (2021): S422—S423. http://dx.doi.org/10.1192/j.eurpsy.2021.1127.

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IntroductionAnticholinergic medications block cholinergic transmission. The central effects of anticholinergic drugs can be particularly marked in patients with dementia. Furthermore, anticholinergics antagonise the effects of cholinesterase inhibitors, the main dementia treatment.ObjectivesThis study aimed to assess anticholinergic drug prescribing among dementia patients before and after admission to UK acute hospitals.Methods352 patients with dementia were included from 17 hospitals in the UK. All were admitted to surgical, medical or Care of the Elderly wards in 2019. Information about pat
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Sargent, Lana, Matthew Barrett, Huma Nawaz, et al. "VULNERABILITY TO ANTICHOLINERGIC MEDICATION ASSOCIATED FRAILTY IN LOW-INCOME MINORITY OLDER ADULTS." Innovation in Aging 6, Supplement_1 (2022): 564. http://dx.doi.org/10.1093/geroni/igac059.2126.

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Abstract Low-income minority older adults are highly susceptible to drug adverse effects of medications due to aging, comorbidities, and polypharmacy. Several studies have demonstrated anticholinergic medication is associated with frailty, supporting the hypothesis for mechanistic peripheral nervous system effects. The goal of this cohort study is to determine peripheral nervous system effects of anticholinergic medication exposure with frailty by conducting a sensitivity analysis using multiple anticholinergic tools. Spearman correlation matrix and intraclass correlation coefficients (ICC) ar
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Kennelly, Sean P., Adam H. Dyer, Claire Murphy, and Brian Lawlor. "98 Use of Drgs with Anticholinergic Properties in People Living with Alzheimer’s Disease: Data from NILVAD." Age and Ageing 48, Supplement_3 (2019): iii17—iii65. http://dx.doi.org/10.1093/ageing/afz103.58.

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Abstract Background Prolonged exposure to anticholinergic medication, particularly in midlife, is associated with increased risk of cognitive impairment/dementia. Less well explored is the ongoing use of drugs with anticholinergic properties in patients with Alzheimer’s Disease (AD), where the potential to accelerate cognitive decline may be greatest. Methods We analysed medication data from the NILVAD trial, a clinical trial examining the efficacy of Nilvadapine in mild-moderate Alzheimer’s Disease (AD). Drgs were coded based on their Anatomical Therapeutic Chemical (ATC) classification and A
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Dissertations / Theses on the topic "Anticholinergic burden"

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Dharia, Sheetal. "The Effect of Anticholinergic Burden on Functional Outcomes in Patients with Moderate to Severe Alzheimer’s Disease." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2248.

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Background: Alzheimer’s disease (AD) is the most common form of dementia and is characterized by a progressive loss of memory, judgment, and thinking in older adults. The current treatment is cholinesterase inhibitors, which increase acetylcholine at the synapse. Medications with anticholinergic (AC) activity are given for a variety reasons including for the treatment of comorbid conditions or side effects of cholinesterase inhibitors (ChEIs). These drugs inhibit acetylcholine in the brain. Studies have shown the detrimental outcomes of using AC medications with ChEIs in older adults. Moreo
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Lavrador, Ana Marta Almeida Aveiro Pimentel. "Quantificação da carga anticolinérgica como preditor de resultados clínicos negativos no idoso – um contributo para a prática clínica." Doctoral thesis, 2022. http://hdl.handle.net/10316/98291.

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Tese de Doutoramento em Ciências Farmacêuticas apresentada à Faculdade de Farmácia da Universidade de Coimbra.<br>O envelhecimento da população é uma realidade que caracteriza as sociedades atuais. Os idosos são os principais consumidores de medicamentos, utilizando, muitas vezes, um elevado número de fármacos simultaneamente. A utilização de medicamentos está associada a potenciais danos iatrogénicos graves, situação particularmente relevante na população idosa, em que as alterações fisiológicas do envelhecimento condicionam uma maior suscetibilidade ao aparecimento de efeitos adversos.
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Book chapters on the topic "Anticholinergic burden"

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Brar, Gurjot, Niamh Mulryan, and Fintan Sheerin. "Anticholinergic Burden in People with Intellectual Disabilities." In The Palgrave Encyclopedia of Disability. Springer Nature Switzerland, 2024. https://doi.org/10.1007/978-3-031-40858-8_251-1.

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M. Lisi, Donna. "Assessing Anticholinergic Effects in Older Adults." In Geriatrics [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94555.

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Anticholinergic medications are widely used in older adults and are a common source of adverse events in this population. Common drug classes include antiarrhythmics, antidepressants, antiemetics, first generation antihistamines, urinary incontinence antimuscarinic agents, antiparkinsonian agents, antipsychotics, antispasmodics, and skeletal muscle relaxants. These drugs have been associated with delirium, cognitive impairment, sedation, dizziness, falls, fracture, constipation, urinary retention, blurred vision, tachycardia and dry mouth. If possible, these drugs should be avoided in older ad
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Joshi, Yash B. "Cholinergic Functioning, Cognition, and Anticholinergic Medication Burden in Schizophrenia." In Current Topics in Behavioral Neurosciences. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/7854_2022_400.

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Persico, Amelia L., and Erica L. Wegrzyn. "Geriatric Pain Pharmacotherapy." In Pain. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197542873.003.0046.

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The care of older patients requiring pain and symptom management is complex because special attention must be paid to physiologic changes as aging progresses. An array of age-related pharmacokinetic changes occur in the aging adult, often exacerbated by polypharmacy and anticholinergic medications. The approach to an elderly patient requires review of all potentially inappropriate medications (PIMs), assessment for drug-drug and drug-disease state interactions, and a focus on rational opioid therapy. Medications no longer considered necessary should be de-prescribed when possible to reduce the
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Reynard, John, Simon F. Brewster, Suzanne Biers, and Naomi Laura Neal. "Urinary incontinence and female urology." In Oxford Handbook of Urology. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198783480.003.0005.

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All aspects of female and male urinary incontinence assessment, investigation, and management are outlined. Definitions of incontinence are provided, with a review of the epidemiology, risk factors, and management of stress urinary incontinence (SUI), post-prostatectomy (male) incontinence, overactive bladder syndrome (OAB), mixed urinary incontinence, and incontinence in older populations. Conservative, drug, and surgical therapies are explored, including bulking agents, synthetic mid-urethral tapes, colposuspension, autologous fascial slings, and artificial urinary sphincters (AUS) for femal
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"Anticholinergics." In Handbook of Disease Burdens and Quality of Life Measures. Springer New York, 2010. http://dx.doi.org/10.1007/978-0-387-78665-0_5103.

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Conference papers on the topic "Anticholinergic burden"

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Formoso, Carolina Rodrigue, Raphael Machado Castilhos, Wyllians Vendramini Borelli, Matheus Zschornack Strelow, and Marcia Fagundes Chaves. "ANTICHOLINERGIC BURDEN IN DEMENTIA." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda031.

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Background: The anticholinergic burden is associated with a greater risk of functional/ cognitive decline and morbidity/mortality. Objectives: Our aim was to quantify the anticholinergic burden in the first visit in our dementia tertiary outpatient clinic. Methods: We performed a retrospective analysis of all first visit medical records of patients referred from primary health care to the outpatient dementia clinic of a tertiary hospital in Porto Alegre with a final diagnosis of dementia or Mild Cognitive Impairment (MCI) between 2014-2019. We evaluated all medications in use and we calculated
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Villalba-Moreno, A., E. Alfaro-Lara, S. Sanchez-Hidalgo, et al. "OHP-027 Anticholinergic burden web tool calculator." In 22nd EAHP Congress 22–24 March 2017 Cannes, France. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/ejhpharm-2017-000640.421.

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Florido Francisco, M., R. Sanchez Del Moral, and I. Corriente Gordón. "5PSQ-057 Anticholinergic burden assessment in institutionalised patients." In 28th EAHP Congress, Bordeaux, France, 20-21-22 March 2024. British Medical Journal Publishing Group, 2024. http://dx.doi.org/10.1136/ejhpharm-2024-eahp.391.

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Byrne, Patrick, and Jennifer Hoblyn. "H55 Anticholinergic drug burden and cognitive function in huntington’s disease." In EHDN 2018 Plenary Meeting, Vienna, Austria, Programme and Abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/jnnp-2018-ehdn.233.

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Velasco Costa, J., JM Peñalver Gonzalez, and M. Martinez De Guzman. "5PSQ-182 Anticholinergic burden in patients admitted to a psychiatric hospital." In 25th Anniversary EAHP Congress, Hospital Pharmacy 5.0 – the future of patient care, 23–28 March 2021. British Medical Journal Publishing Group, 2021. http://dx.doi.org/10.1136/ejhpharm-2021-eahpconf.301.

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Plaza Diaz, A., J. Ruiz Ramos, A. Juanes Borrego, M. Blazquez Andion, L. Lopez Vinardell, and MA Mangues Bafalluy. "4CPS-002 Anticholinergic burden in constipated patient admitted to an emergency department." In 25th EAHP Congress, 25th–27th March 2020, Gothenburg, Sweden. British Medical Journal Publishing Group, 2020. http://dx.doi.org/10.1136/ejhpharm-2020-eahpconf.103.

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Cuenca, MR Cantudo, BM Muñoz Cejudo, MA Mora Mora, G. Fernández Martínez, and T. Cantal Sánchez. "4CPS-180 Applying different scales for calculating the anticholinergic burden in older patients." In Abstract Book, 23rd EAHP Congress, 21st–23rd March 2018, Gothenburg, Sweden. British Medical Journal Publishing Group, 2018. http://dx.doi.org/10.1136/ejhpharm-2018-eahpconf.270.

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Mensa Vendrell, M., A. Rizo Gómez, R. Romero Dominguez, G. Ballesteros Cabañas, M. Barrantes González, and D. Soy Muner. "4CPS-188 Pharmaceutical intervention to reduce the anticholinergic burden in older hospitalised patients." In 25th EAHP Congress, 25th–27th March 2020, Gothenburg, Sweden. British Medical Journal Publishing Group, 2020. http://dx.doi.org/10.1136/ejhpharm-2020-eahpconf.289.

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Santos, Adriana Nancy Medeiros dos, Natalia Gomes Gonçalves, Isabela M. Benseñor, et al. "Anticholinergic burden and cognitive decline in the ELSA-Brasil study: a prospective study." In Reunião de Pesquisadores em Doença de Alzheimer e Desordens Relacionadas. Academia Brasileira de Neurologia, 2024. http://dx.doi.org/10.22491/19805764/041.

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Prado-Mel, E., P. Ciudad-Gutiérrez, H. Rodríguez-Ramallo, MI Galván-Borrás, R. Ramos-Moreno, and J. Cañizares-Huartemendicoa. "4CPS-368 Systematic review of the association between anticholinergic burden and xerostomia and xerophthalmia." In 25th Anniversary EAHP Congress, Hospital Pharmacy 5.0 – the future of patient care, 23–28 March 2021. British Medical Journal Publishing Group, 2021. http://dx.doi.org/10.1136/ejhpharm-2021-eahpconf.200.

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