Academic literature on the topic 'Anticoagulation monitoring'

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Journal articles on the topic "Anticoagulation monitoring"

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Smythe, Maureen A., and Anne Caffee. "Anticoagulation Monitoring." Journal of Pharmacy Practice 17, no. 5 (2004): 317–26. http://dx.doi.org/10.1177/0897190004271775.

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Optimal management of anticoagulant therapy requires an understanding of the laboratory tests often employed to guide therapy. The activated partial thromboplastin time (aPTT) can detect abnormalities in the intrinsic and common clotting pathways. Despite numerous limitations in the aPTT test, it remains the gold standard for monitoring unfractionated heparin and direct thrombin inhibitor therapy. The aPTT can be performed in the central laboratory or at the bedside (point of care [POC] testing). The activated clotting time (ACT) is a POC test that is routinely employed to monitor high-dose he
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Ng, Valerie L. "Anticoagulation Monitoring." Clinics in Laboratory Medicine 29, no. 2 (2009): 283–304. http://dx.doi.org/10.1016/j.cll.2009.05.003.

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Pence, Catherine, and Kimberly McErlane. "Anticoagulation Self-Monitoring." AJN, American Journal of Nursing 105, no. 10 (2005): 62–65. http://dx.doi.org/10.1097/00000446-200510000-00036.

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EBBERT, JON O., and ERIC G. TANGALOS. "Anticoagulation Self-Monitoring." Internal Medicine News 39, no. 20 (2006): 44. http://dx.doi.org/10.1016/s1097-8690(06)74379-7.

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Chandler, Wayne L. "Anticoagulation Without Monitoring." American Journal of Clinical Pathology 140, no. 5 (2013): 606–7. http://dx.doi.org/10.1309/ajcpe8cwkovg4agx.

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Li Wan Po, Alain. "Self-monitoring of anticoagulation." Lancet 379, no. 9828 (2012): 1788–89. http://dx.doi.org/10.1016/s0140-6736(12)60757-0.

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McPherson, Mary Lynn. "Home oral anticoagulation monitoring." Journal of Home Health Care Practice 4, no. 1 (1992): 63–77. http://dx.doi.org/10.1177/108482239200400110.

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Hambleton, Julie. "Home Monitoring of Anticoagulation." Journal of Thrombosis and Thrombolysis 16, no. 1/2 (2003): 39–42. http://dx.doi.org/10.1023/b:thro.0000014591.32012.1f.

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McRae, Hannah L., Leah Militello, and Majed A. Refaai. "Updates in Anticoagulation Therapy Monitoring." Biomedicines 9, no. 3 (2021): 262. http://dx.doi.org/10.3390/biomedicines9030262.

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In the past six decades, heparin and warfarin were the primary anticoagulants prescribed for treatment and prophylaxis of venous thromboembolism worldwide. This has been accompanied by extensive clinical knowledge regarding dosing, monitoring, and reversal of these anticoagulants, and the resources required to do so have largely been readily available at small and large centers alike. However, with the advent of newer oral and parenteral anticoagulants such as low molecular weight heparins, factor Xa inhibitors, and direct thrombin inhibitors in recent years, new corresponding practice guideli
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Maier, Cheryl L., and Roman M. Sniecinski. "Anticoagulation Monitoring for Perioperative Physicians." Anesthesiology 135, no. 4 (2021): 738–48. http://dx.doi.org/10.1097/aln.0000000000003903.

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From preoperative medications to intraoperative needs to postoperative thromboprophylaxis, anticoagulants are encountered throughout the perioperative period. This review focuses on coagulation testing clinicians utilize to monitor the effects of these medications.
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Dissertations / Theses on the topic "Anticoagulation monitoring"

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Coleman, B. "Requirements for a patient self monitoring service for oral anticoagulation." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1352827/.

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Self-care is considered a means of meeting the challenge of providing care to patients with long-term conditions. However this has not achieved widespread penetration in the UK, the reasons for which are unclear. This research examined one area of self-care in depth - self-monitoring of oral anticoagulation therapy. The aim was to derive the requirements for an anticoagulation patient self-monitoring service from an analysis of the drivers for, the benefits of, the barriers to, and the challenges of establishing this service from the perspectives of key stakeholders – patients, healthcare prof
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Moussa, Mouhamed Djahoum. "Déterminants cliniques, physiopathologiques et pronostics associés aux complications liées à l’hémostase au cours des assistances circulatoires de courte durée à pompe centrifuge." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILS055.

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La problématique de cette thèse est la caractérisation des complications liées à l’hémostase chez le patient assisté par ECMO-VA périphérique afin d’en améliorer la prévention et de rationaliser les approches antithrombotiques en usage. Dans une première étude, nous avons décrit qualitativement et quantitativement la composition des thrombi formés sur les circuits d’ECMO-VA. Nous avons observé que ces thrombi sont majoritairement composés de VWF, de fibrine et dans une moindre proportion de plaquettes et d’érythrocytes. Notre approche quantitative a également permis de mettre en évidence la pr
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van, Tienen EC. "Optimising warfarin management: an exploration of pharmacist-delivered models of care." Thesis, 2012. https://eprints.utas.edu.au/16143/2/whole-excl-app-vantienen-thesis-2012.pdf.

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Warfarin has been the mainstay of preventing and treating thromboembolism for over 50 years and is currently taken by over 200,000 Australians. Optimal management of warfarin relies on regular monitoring of the International Normalised Ratio (INR), appropriate dose adjustment, effective communication and comprehensive patient education. Therapy may be managed by a range of healthcare providers in a variety of settings, and by patients themselves, although management in Australia has tended to focus on traditional office and pathology based models. Internationally, however, alternative models o
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Ferreira, Cristina Maria Santos de Sousa. ""Modelo de acompanhamento de Doentes a tomar Anticoagulantes Orais, em âmbito de Consulta Farmacêutica. Proposta de Formação Avançada"." Master's thesis, 2017. http://hdl.handle.net/10316/83689.

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Dissertação de Mestrado em Farmacologia Aplicada apresentada à Faculdade de Farmácia<br>Racional: Os anticoagulantes orais são habitualmente utilizados na prática clinica para o tratamento e prevenção de doenças cardiovasculares, acidentes cerebrovasculares e tromboembolismo venoso. Para além dos antagonistas da vitamina K, surgiram recentemente outros anticoagulantes orais com um mecanismo de ação mais específico e aparentemente com menos limitações. Os novos anticoagulantes dispensam a monitorização analítica de rotina, mas não dispensam o acompanhamento do doente por um profissional de saúd
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Books on the topic "Anticoagulation monitoring"

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Allen, Brown, Canadian Coordinating Office for Health Technology Assessment., and Canadian Agency for Drugs and Technologies in Health., eds. Devices for point-of-care monitoring of long-term oral anticoagulation therapy: Clinical and cost effectiveness. Canadian Coordinating Office for Health Technology Assessment, 2007.

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Waldmann, Carl, Neil Soni, and Andrew Rhodes. Haematological drugs. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199229581.003.0014.

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Anticoagulants and heparin-induced thrombocytopenia 220Thrombolysis 224Antifibrinolytics 226For &gt;50 years, the options for therapeutic anticoagulation were limited to unfractionated heparin (UFH) and oral vitamin K antagonists. While highly effective, both drugs have major safety problems. Both have narrow therapeutic ranges, substantial interindividual dose variability, major side effects and require regular therapeutic drug monitoring, with a narrow therapeutic window and high incidence of bleeding complications....
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Prout, Jeremy, Tanya Jones, and Daniel Martin. Cardiac anaesthesia. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199609956.003.0014.

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This chapter, written by Anaesthetists from the Heart Hospital, describes the general principles in cardiac anaesthesia. Patient pre-assessment, perioperative monitoring, management of anticoagulation, methods of patient cooling and rewarming, cardiopulmonary bypass and postoperative complications such as tamponade and neurological dysfunction are all discussed in detail. The principles of intra-aortic balloon pump counterpulsation with indications and practical aspects of use are included. The principles of providing anaesthesia for the adult patient with congenital heart disease follow a des
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Adam, Sheila, Sue Osborne, and John Welch. Haematological problems. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199696260.003.0012.

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This chapter discusses specific haematological disorders that require the patient to be admitted to the critical care unit. It describes the normal physiology of blood cells, clotting mechanisms, and fibrinolysis, and the management of related conditions such as thrombocytopenia, leukaemia, and clotting disorders such as disseminated intravascular coagulation. It also includes the management of the critical care patient with haematological malignancy. Specific therapies such as plasma exchange and anticoagulation therapy are discussed in detail and the monitoring of coagulation tests is explai
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Bueno, Héctor, and José A. Barrabés. Non-ST-segment elevation acute coronary syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0046.

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Non-ST-segment elevation acute coronary syndromes are life-threatening disorders, usually caused by acute coronary thrombosis and subsequent myocardial ischaemia, presenting without persistent ST-segment elevation in the initial electrocardiogram. According to the occurrence of myocardial necrosis, non-ST-segment elevation acute coronary syndromes are divided into non-ST-segment myocardial infarction or unstable angina. The management of non-ST-segment elevation acute coronary syndromes requires an early diagnosis and risk stratification, urgent hospitalization, monitoring, and medical treatme
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Bueno, Héctor, and José A. Barrabés. Non-ST-segment elevation acute coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0046_update_001.

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Non-ST-segment elevation acute coronary syndromes are life-threatening disorders, usually caused by acute coronary thrombosis and subsequent myocardial ischaemia, presenting without persistent ST-segment elevation in the initial electrocardiogram. According to the occurrence of myocardial necrosis, non-ST-segment elevation acute coronary syndromes are divided into non-ST-segment myocardial infarction or unstable angina. The management of non-ST-segment elevation acute coronary syndromes requires an early diagnosis and risk stratification, urgent hospitalization, monitoring, and medical treatme
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Bueno, Héctor, and José A. Barrabés. Non-ST-segment elevation acute coronary syndromes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0046_update_002.

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Non-ST-segment elevation acute coronary syndromes are life-threatening disorders, usually caused by acute coronary thrombosis and subsequent myocardial ischaemia, presenting without persistent ST-segment elevation in the initial electrocardiogram. According to the occurrence of myocardial necrosis, non-ST-segment elevation acute coronary syndromes are divided into non-ST-segment myocardial infarction or unstable angina. The management of non-ST-segment elevation acute coronary syndromes requires an early diagnosis and risk stratification, urgent hospitalization, monitoring, and medical treatme
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0066.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0066_update_001.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Torbicki, Adam, Marcin Kurzyna, and Stavros Konstantinides. Pulmonary embolism. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0066_update_002.

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Pulmonary embolism is usually a consequence of deep vein thrombosis, and together the two conditions are known as venous thromboembolism. Non-thromboembolic causes of pulmonary embolism are rare. Pulmonary thromboembolism is a potentially life-threatening disease, if left untreated. This is due to a natural tendency towards early recurrence of pulmonary emboli which may lead to fatal right ventricular failure. In more severe cases, secondary right ventricular failure may result from myocardial ischaemia and injury caused by systemic hypotension and adrenergic overstimulation. Clinical presenta
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Book chapters on the topic "Anticoagulation monitoring"

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Jayaram, Kavitha. "Monitoring Anticoagulation." In Transfusion Practice in Clinical Neurosciences. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-0954-2_38.

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Gurbel, Paul A., and Udaya S. Tantry. "Antiplatelet Drug Resistance and Variability in Response: The Role of Antiplatelet Therapy Monitoring." In Antiplatelet and Anticoagulation Therapy. Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-4297-3_2.

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Sharda, Anish V., and Jeffrey I. Zwicker. "Anticoagulation Drugs: Indications, Therapeutic Monitoring, and Antidotes." In Nonmalignant Hematology. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30352-9_44.

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Yost, Gregory W., and Steven R. Steinhubl. "Monitoring and Reversal of Anticoagulation and Antiplatelet Agents." In Interventional Cardiology. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118983652.ch49.

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Inaba, Wakiko, Akihiko Watanabe, Akitomo Koide, Sinnzo Sumita, Hiroaki Watanabe, and Akiyosi Namiki. "Use of the Coagulation Monitor 512 for Reversal of Heparin-Induced Anticoagulation and the Effect of Fresh Frozen Plasma." In Computing and Monitoring in Anesthesia and Intensive Care. Springer Japan, 1992. http://dx.doi.org/10.1007/978-4-431-68201-1_121.

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McChesney, Ian. "Process Support for Continuous, Distributed, Multi-party Healthcare Processes - Applying Workflow Modelling to an Anticoagulation Monitoring Protocol." In Ubiquitous Computing and Ambient Intelligence. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-48746-5_26.

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Kinard, Theresa N. "Anticoagulation Monitoring and Reversal." In Mayo Clinic Critical and Neurocritical Care Board Review, edited by Eelco F. M. Wijdicks, James Y. Findlay, William D. Freeman, and Ayan Sen. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190862923.003.0055.

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The balance of natural procoagulant and anticoagulant activity within the body is delicate, and a minor disruption may lead to bleeding or clotting complications. Anticoagulation in critical illness is often necessary for a host of reasons, either prophylactic or therapeutic. This chapter reviews common anticoagulation management issues in the critically ill patient, such as optimal laboratory monitoring of anticoagulation therapy and urgent reversal options, focusing on the most common anticoagulants used in current practice.
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Keeling, David. "Therapeutic anticoagulation." In Oxford Textbook of Medicine. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199204854.003.161602_update_002.

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Low molecular weight heparins (LMWH) have largely replaced unfractionated heparin. Their much more predictable anticoagulant response combined with high bioavailability after subcutaneous injection means that the dose can be calculated by body weight and given subcutaneously without any monitoring or dose adjustment. Their widespread use resulted in most patients with deep vein thrombosis being managed as outpatients, and this is also increasingly the case for uncomplicated pulmonary embolism....
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Mazzeffi, Michael, and Ashleigh Lowery. "Anticoagulation Options." In Coronary and Cardiothoracic Critical Care. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-8185-7.ch022.

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There are multiple indications for anticoagulation in the cardiac surgery intensive care unit including cardiac valve replacement, mechanical circulatory pumps (ECMO and ventricular assist devices), deep vein thrombosis prophylaxis, treatment of heparin-induced thrombocytopenia, and treatment of other thrombotic conditions including pulmonary embolism. Anticoagulant medications broadly fall into two categories: antiplatelet drugs and inhibitors of protein clotting factors. In this chapter we will review anticoagulant medications, therapeutic drug monitoring, common indications for anticoagulat
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Keeling, David. "Therapeutic anticoagulation." In Oxford Textbook of Medicine, edited by Jeremy Dwight. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0376.

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The main indications for therapeutic anticoagulation are venous thromboembolism, deep vein thrombosis, and pulmonary embolism, and the prevention of stroke in patients with atrial fibrillation or mechanical heart valves. Low-molecular-weight heparins have largely replaced unfractionated heparin in its treatment. Their much more predictable anticoagulant response combined with high bioavailability after subcutaneous injection means that the dose can be calculated by body weight and given subcutaneously without any monitoring or dose adjustment. Their widespread use resulted in most patients wit
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Conference papers on the topic "Anticoagulation monitoring"

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Seveso, M. P., A. Macagni, S. Viganò D'Angelo, C. Manotti, P. A. Bonini, and A. D'Angelo. "PROTHROMBIN TIME MONITORING OF ORAL ANTICOAGULANT TREATMENT: COMPARISON OF INSTRUMENTS AND THROMBOPLASTINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643262.

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The prothrombin time (PT) is the most widely used assay to monitor oral anticoagulation (OA). Although it has been established that both thromboplastin and instrumentation significantly affect the results, major standardization attempts have been devoted to the calibration of reagents rather than of instruments. To provide safe laboratory monitoring of OA, an International Sen sitivity Index (ISI) for thromboplastin has been introduced. We have compared two automatic coagulometers, the ACL (Instrumentation Laboratory), a laser-nephelometer centrifugal analyzer which measures the intensity of t
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Tshikudi, Diane M., Michael N. Andrawes, and Seemantini K. Nadkarni. "Anticoagulation and hemostasis monitoring at the bedside during cardiac surgical procedures (Conference Presentation)." In Optical Diagnostics and Sensing XX: Toward Point-of-Care Diagnostics, edited by Gerard L. Coté. SPIE, 2020. http://dx.doi.org/10.1117/12.2546717.

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Tshikudi, Diane M., Alexandra Wirth, Michael Andrawes, and Seemantini Nadkarni. "Bedside anticoagulation monitoring during cardiac surgery with a drop of whole blood (Conference Presentation)." In Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII, edited by Anita Mahadevan-Jansen. SPIE, 2019. http://dx.doi.org/10.1117/12.2510608.

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Shand, R. A., K. D. Butler, and J. A. Davies. "HEPARIN ANTICOAGULATION AND ITS EFFECT ON ARTERIAL THROMBUS FORMATION IN THE RABBIT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643173.

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Injury to the rabbit carotid was induced by clamping the vessel for 5 minutes. Deposition of radiolabelled fibrinogen (F) or platelets (PL) on the injured carotid was monitored continuously, for 45 minutes, using an iodide crystal scintillation detector positioned over the vessel linked to an automated isotope monitoring system (AIMS 8000). The results were expressed as the maximal increase or as the area under the curve (AUC) for the recording period.Following injury there was a simultaneous increase in both F associated and PL associated radioactivity of 29% (median value, range 10.9 - 4.37)
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Tshikudi, Diane M., Alexandra G. Wirth, Michael N. Andrawes, and Seemantini K. Nadkarni. "Anticoagulation and hemostasis monitoring during cardiac surgery with a drop of whole blood using a novel optical sensor." In Novel Biophotonics Techniques and Applications, edited by Arjen Amelink and Seemantini K. Nadkarni. SPIE, 2019. http://dx.doi.org/10.1117/12.2537923.

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Tshikudi, Diane M., Alexandra G. Wirth, Michael N. Andrawes, and Seemantini K. Nadkarni. "Monitoring Anticoagulation and Hemostasis in Cardiac Surgical Patients with a Drop of Whole Blood Using a Novel Optical Sensor." In Clinical and Translational Biophotonics. OSA, 2020. http://dx.doi.org/10.1364/translational.2020.tw4b.4.

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Hulbert, J. C., J. A. Krishnan, E. Heather, et al. "A Novel Approach to Medical Monitoring During the SARS-CoV-2 Pandemic Supporting the ACTIV 4B Outpatient Anticoagulation Trial." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1749.

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Stewart, G. J., J. W. Lachman, P. D. Alburger, M. C. Ziskin, C. M. Philips, and K. Jensen. "VENODILATION AND DEVELOPMENT OF DEEP VEIN THROMBOSIS IN TOTAL HIP AND KNEE REPLACEMENT PATIENTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643696.

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Postoperative deep vein thromboisis(DVT) is a frequent complication following total hip (THR) or knee (TKR)replacement but no test has been devised to identify specific patientswho will develop DVT. Because conventional prophylaxis does not significantly reduce the incidence of DVT, monitoring is widely used to detect evolving thrombosis. More intense anticoagulation (adjusted dose heparin,two step warfarin) may be effective but requires laboratory tests and carries increased risk of bleeding. Itwould be an economic and medical advantage to restrict prophylaxis and monitoring to patients who w
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