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Relevant bibliographies by topics / Anticonvulsant agents

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Academic literature on the topic 'Anticonvulsant agents'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Anticonvulsant agents"

1

Mishchenko, Mariia, Sergiy Shtrygol, Danylo Kaminskyy, and Roman Lesyk. "Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents." Scientia Pharmaceutica 88, no. 1 (2020): 16. http://dx.doi.org/10.3390/scipharm88010016.

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Here, we describe the synthesis and anticonvulsant activity of thiazole-bearing hybrids based on 2-imino-4-thiazolidinone and 2,4-dioxothiazolidine-5-carboxylic acid cores. The structure of target compounds was based on the following: (i) A combination of two thiazole cores; (ii) similarity to ralitolin’s structure; (iii) the compliance with structural requirements for the new anticonvulsants. Target compounds were synthesized via known approaches based on Knoenavegel reaction, alkylation reaction, and one-pot three-component reaction. Anticonvulsant properties of compounds were evaluated in t

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Dreifuss, Fritz E. "Anticonvulsant Agents." Critical Care Clinics 7, no. 3 (1991): 521–32. http://dx.doi.org/10.1016/s0749-0704(18)30294-x.

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Trisovic, Nemanja, Gordana Uscumlic, and Slobodan Petrovic. "Hydantoins: Synthesis, properties and anticonvulsant activity." Chemical Industry 63, no. 1 (2009): 17–31. http://dx.doi.org/10.2298/hemind0901017t.

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Hydantoin is a five-membered cyclic ureide that is present in numerous biologically active compounds including antiarrhytmics, anticonvulsants and antitumor agents. This paper describes different ways of synthesis of hydantoin-derivatives, their physical properties and reactivity. Also, the most widely used hydantoin anticonvulsants and the analysis of structureactivity relationships of anticonvulsant drugs in terms of lipophilicity and hydrogen bonding are presented here.

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Banjac, Nebojsa, Nemanja Trisovic, Natasa Valentic, Gordana Uscumlic, and Slobodan Petrovic. "Succinimides: Synthesis, properties and anticonvulsant activity." Chemical Industry 65, no. 4 (2011): 439–53. http://dx.doi.org/10.2298/hemind110224030b.

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Succinimide is a cycle imide of succinic acid that is present in numerous biologically active compounds including anticonvulsants, antitremor, anti-Parkinson`s agents. This paper describes different ways of synthesis of succinimide-derivatives their physical properties and reactivity. Also, the most widely used succinimide anticonvulsants and the analysis of structure-activity relationships of anticonvulsant drugs in terms of lipophilicity and hydrogen bonding are presented here.

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Malawska, Barbara. "New Anticonvulsant Agents." Current Topics in Medicinal Chemistry 5, no. 1 (2005): 69–85. http://dx.doi.org/10.2174/1568026053386944.

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Yaduwanshi, Phool Singh, Sheelu Singh, Prinsi Sahapuriya, Priyanka Dubey, Jyoti Thakur, and Savita Yadav. "Synthesis of Some Noval Qunazolinone Derivatives for their Anticonvulsant Activity." Oriental Journal Of Chemistry 40, no. 2 (2024): 369–73. http://dx.doi.org/10.13005/ojc/400207.

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The quinoline family comprises an appealing group of heterocyclic compounds, with quinazolinones and their synthetic analogs being of particular interest. To synthesize 3- amino 2-phenyl quinazolinones, anthranilic acid and its substituted derivatives were employed as initial materials. The MES method was utilized to evaluate the anticonvulsant activity of the developed substances on albino mice, with phenytoin serving as a benchmark anticonvulsant medication.The synthesized compounds demonstrated noteworthy anticonvulsant activity, comparable to that of established prescription medications. A

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Mayor, M. Marin, J. Lopez Alvarez, M. D. Riaza Perez, A. Quintana Perez, and G. Rubio Valladolid. "Use of anticonvulsant agents in the management of alcohol dependence." European Psychiatry 26, S2 (2011): 78. http://dx.doi.org/10.1016/s0924-9338(11)71789-8.

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BackgroundAlcoholism is a chronic relapsing disorder characterized by compulsive drinking, alcohol seeking, loss of control over alcohol consumption, and impaired social and occupational functioning. Treatment of Alcohol Dependence (AD) comprises two steps, detoxification and relapse prevention (RP). Traditionally, long half-life benzodiazepines have been the most widely used agents for alcohol detoxification. On the other hand, disulfiram, naltrexone and acamprosate are the three drugs that have been approved for relapse prevention. In the last decades, nevertheless, there is a growing intere

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Goodwin, Frederick K., and S. Nassir Ghaemi. "The Impact of Mood Stabilizers on Suicide in Bipolar Disorder: A Comparative Analysis." CNS Spectrums 5, S1 (2000): 12–18. http://dx.doi.org/10.1017/s1092852900023245.

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AbstractWhich mood stabilizers are the most effective in reducing suicide rates in patients with bipolar disorder? This paper reviews the literature and compares the data on two types of mood-stabilizing agents, lithium and anticonvulsants. Compared with the large amount of data on lithium, there is surprising little information available on the effects of anticonvulsants on mortality in manic-depressive illness. Each was also assessed in terms of suicide risk factors such as depression and mixed episodes, rapid cycling, substance abuse, anxiety and panic, and central serotonergic function. On

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Nair, B. R. "Anticonvulsant agents and osteomalacia." Medical Journal of Australia 152, no. 5 (1990): 279–80. http://dx.doi.org/10.5694/j.1326-5377.1990.tb120938.x.

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Jakovleva, Ekaterina E., Stanislav P. Foksha, Marija A. Brusina, et al. "Studying the anticonvulsive activity of new ligands of NDMA-receptor complex – imidazole-4,5-dicarbonic acid derivatives." Reviews on Clinical Pharmacology and Drug Therapy 18, no. 2 (2020): 149–54. http://dx.doi.org/10.17816/rcf182149-154.

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NMDA receptors were proven to play a significant role in the processes of epileptogenesis. Experimental data indicate a significant anticonvulsant effect of NMDA receptor antagonists, but the use of the studied NMDA ligands remains limited due to their low efficiency and toxic effects. The aim of the study was to investigate the anticonvulsant effect of new ligands of the glutamate NMDA receptor complex imidazole-4,5-dicarboxylic acid (IDA) derivatives on a model of NMDA-induced convulsions in mice. The tested agents (IEM2258 and IEM2248) were injected into the lateral ventricles of a waking m

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Dissertations / Theses on the topic "Anticonvulsant agents"

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Hasan, Mohamed Yousif. "A pharmacological study on gaba modifying anticonvulsant agents." Thesis, Cardiff University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336178.

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Chessum, Nicola E. A. "The development of new GABA-based anticonvulsant agents." Thesis, University of York, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273822.

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Shah, Vibhakar Jayantilal. "Synthesis of cannabidiol stereoisomers and analogs as potential anticonvulsant agents." Diss., The University of Arizona, 1988. http://hdl.handle.net/10150/184523.

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Anticonvulsant activity of cannabidiol (CBD) has been well documented in various laboratory animal species and also in man. As part of our continuing effort to study and to define the structure anticonvulsant relationship several analogs of CBD were synthesized wherein its structural units, namely, the terpene ring, aryl ring and/or side chain were systematically modified. These analogs include the: (1) unnatural (+)-Cannabidol (1b), (2) Delta-3-carenyl analog-(+)-carenadiol (45a), its diacetate (45b) and its 1",1"-dimethylheptyl side chain analog (45c), and (3) unnatural 7-acetoxycannabidiol

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Barcelos, Caroline Coutinho de 1982. "Efeitos neuromusculares do atracurio e do rocuronio em ratos pre-tratados com carbamazepina e fenobarbital : estudo in vitro e in vivo." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310321.

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Orientadores: Lea Rodrigues Simioni, Yoko Oshima Franco<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-09T02:12:41Z (GMT). No. of bitstreams: 1 Barcelos_CarolineCoutinhode_M.pdf: 1481920 bytes, checksum: 51a5dae81283795439bd5ed51ac09f60 (MD5) Previous issue date: 2007<br>Resumo: Atracúrio (ATC) e rocurônio (ROC) são bloqueadores neuromusculares de ação intermediária. Neste estudo, seus efeitos neuromusculares foram investigados in vitro e in vivo em ratos pré-tratados, via gavagem (7d), com os anticonvulsiva

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Ward, Sarah. "The Development of Exogenous Anticonvulsants and Endogenous Uracil-Based Antiepileptic Agents." 2011. http://hdl.handle.net/10222/14244.

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Epilepsy is a common neurological disorder for which the development of new and improved therapies is essential. Thus, the central theme of this thesis pertains to the design and synthesis of putative antiepileptic drugs. A substructure search was performed on a database of exogenous compounds to find those that contain a known sodium channel pharmacophore. The anticonvulsant activity of several compounds identified by this search was evaluated, resulting in the recognition of multiple molecular classes from which new anticonvulsant scaffolds could be derived. A series of analogues derived f

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Esteves, Rita Alexandra Romão Sá. "Desafios da contraceção na doente com epilepsia." Master's thesis, 2018. http://hdl.handle.net/10316/82155.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: As mulheres com epilepsia enfrentam múltiplos desafios aquando da escolha de um método contracetivo, em grande parte devido às interações bidirecionais entre contracetivos hormonais e fármacos antiepiléticos. É imperativo que a gravidez destas mulheres seja planeada de modo a evitar os efeitos teratogénicos de certos fármacos antiepiléticos e a assegurar o controlo da epilepsia antes do início da gravidez.Métodos: Foi feita uma pesquisa nas bases de dados PubMed e EMBASE procurando artigos acerc

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Mackintosh, Carolyn, and Sue Elson. "Chronic pain: clinical features, assessment and treatment." 2008. http://hdl.handle.net/10454/6969.

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A significant number of people in the UK experience chronic pain, resulting in high levels of suffering and reduced quality of life. Management of chronic pain is complex, time consuming and not always successful. Good communication between patients and healthcare professionals is essential to ensure realistic treatment plans and outcomes can be negotiated. Accurate assessment is also key, and nurses play a fundamental role in ensuring patients with chronic pain receive the most appropriate care.

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Books on the topic "Anticonvulsant agents"

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S, Meldrum Brian, Williams, Michael, 1947 Jan. 3-, and Princeton Drug Research Symposia (1st : 1989 : Princeton, N.J.), eds. Current and future trends in anticonvulsant, anxiety, and stroke therapy: Proceedings of a symposium held at Princeton, New Jersey, May 21-23, 1989. Wiley-Liss, 1990.

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2

Stahl, S. M. Mood stabilizers. Cambridge University Press, 2009.

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S, Akiskal Hagop, and Tohen Mauricio, eds. Bipolar psychopharmacotherapy: Caring for the patient. John Wiley & Sons, 2006.

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4

L, Faingold Carl, and Fromm Gerhard H, eds. Drugs for control of epilepsy: Actions on neuronal networks involved in seizure disorders. CRC Press, 1992.

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5

J, Epstein Charles, National Down Syndrome Society (U.S.), and Conference on the Neurobiology of Down Syndrome (1985 : New York, N.Y.), eds. The Neurobiology of Down syndrome. Raven Press, 1986.

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6

Gangarapu, Kiran. Development of Isatin As CNS Agents: Anticonvulsant Activity. Anchor Academic Publishing. ein Imprint der Diplomica Verlag GmbH, 2014.

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7

Otis, James A. D. Non-Opioid Pharmacotherapies for Chronic Pain (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0015.

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The objective of chapter 15 is to describe analgesic approaches to chronic pain, excluding opioids. As such, it emphasizes, first, the available pharmacotherapies; and then procedures. The pharmacotherapies divide into analgesics, such as non-steroidal anti-inflammatory drugs (NSAIDs); adjuvant analgesics, such as tricyclic antidepressants and anticonvulsants; oral anesthetic agents (cardiotropics); adrenergic agonists; topical agents such as capsaicin and local anesthetic solutions and ointments; and muscle relaxants such as cyclobenzaprine, tizanidine, and baclofen. Interventions include man

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Nobles, Ryan. Pharmacology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190217518.003.0008.

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This chapter focuses on principles of pharmacokinetics, pharmacodynamics, adverse effects, drug interactions, and common indications with regard to opioids, nonsteroidal anti-inflammatory agents, acetaminophen, anticonvulsants, and antidepressants. The questions are formulated to focus on the most relevant topics that may be tested on the listed medications, but it is not a comprehensive review. The information provided should be supplemented with additional study of the cited literature in the Further Reading section for each question.

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Tohen, Mauricio, and Hagop S. Akiskal. Bipolar Psychopharmacotherapy: Caring for the Patient. Wiley & Sons, Incorporated, John, 2007.

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10

Golier, Julia A., Andreas C. Michaelides, Maya Genovesi, Emily Chapman, and Rachel Yehuda. Pharmacological Treatment of Posttraumatic Stress Disorder. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0019.

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Although psychotherapy is considered first-line treatment for posttraumatic stress disorder (PTSD), advances have been made in pharmacological treatment. Based on controlled clinical trials, antidepressants remain the first-line pharmacological treatment. Studies suggest that selective serotonin reuptake inhibitors reduce PTSD-specific symptoms and improve global outcome. Emerging evidence suggests efficacy for venlafaxine. Other individual agents found to be efficacious include imipramine and phenelzine. Prazosin is emerging as a beneficial adjunct for PTSD-related sleep disturbances and nigh

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Book chapters on the topic "Anticonvulsant agents"

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Abou-Khalil, Bassel. "Anticonvulsant Agents: Felbamate." In NeuroPsychopharmacotherapy. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-56015-1_297-1.

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Janssen, Helena, and Paul Boon. "Anticonvulsant Agents: Lamotrigine." In NeuroPsychopharmacotherapy. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-56015-1_300-1.

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Hertzberg, Christoph, and David Neal Franz. "Anticonvulsant Agents: Everolimus." In NeuroPsychopharmacotherapy. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-56015-1_306-1.

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Baumgartner, Christoph, and Martha Britto-Arias. "Anticonvulsant Agents: Zonisamide." In NeuroPsychopharmacotherapy. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-56015-1_310-1.

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Steinhoff, Bernhard J. "Anticonvulsant Agents: Cenobamate." In NeuroPsychopharmacotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-56015-1_469-1.

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Chiron, Catherine. "Anticonvulsant Agents: Stiripentol." In NeuroPsychopharmacotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-56015-1_296-1.

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Panzer, Axel. "Anticonvulsant Agents: Vigabatrin." In NeuroPsychopharmacotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-56015-1_278-1.

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Dinkelacker, Vera, Maria Paola Valenti, and Edouard Hirsch. "Anticonvulsant Agents: Topiramate." In NeuroPsychopharmacotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-56015-1_308-1.

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Rösche, Johannes. "Anticonvulsant Agents: Sulthiame." In NeuroPsychopharmacotherapy. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-56015-1_307-1.

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Bast, Thomas, and Bernhard J. Steinhoff. "Anticonvulsant Agents: Potassium Bromide." In NeuroPsychopharmacotherapy. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-56015-1_304-1.

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Conference papers on the topic "Anticonvulsant agents"

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Abram, Michał, Marcin Jakubiec, Anna Rapacz, Bartłomiej Szulczyk, and Krzysztof Kamiński. "Hybrid compounds based on the pyrrolidine-2,5-dione scaffold as candidates for new wide spectrum anticonvulsant agents." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07497.

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Tsukimata, Márcio Yutaka, Bianca Lumi Inomata da Silva, and Jennison Alves Guimarães. "Açaí: potential anticonvulsant agent." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.064.

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Background: Convulsion is an involuntary contraction of skeletal muscles. When considering vulnerable populations exposed to the mentioned pathophysiological situation, it is recognized that many of them will not have access to the indicated pharmacological treatment. Therefore, the ingestion of açai, Euterpe oleracea (EO) attenuates the problem, acting as an anticonvulsant. Objectives: evaluate the EO as an anticonvulsant agent. Design and setting: It is a bibliographic research and the data collection was done from the PubMed and Scielo databases. Methods: The descriptor used was “Euterpe ol

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Reports on the topic "Anticonvulsant agents"

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VanShura, Kerry E., Megan E. Lyman, Joseph D. McMonagle, Tsung-Ming Shih, and John H. McDonough. Evaluating of the Anticonvulsant Gabapentin against Nerve Agent-Induced Seizures in a Guinea Pig Model. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada525188.

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