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Journal articles on the topic 'Antidiabetic Activities'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Cahyana, Antonius Herry, Agus Rimus Liandi, Syukur Sakban Wicaksono та Akhmad Darmawan. "BIOLOGICAL ACTIVITIES OF EXTRACTS AND SECONDARY METABOLITE OF Macaranga mappa BARK AS AN ANTIDIABETIC BY α-GLUCOSIDASE INHIBITOR, ANTIOXIDANT, AND CYTOTOXICITY". RASAYAN Journal of Chemistry 16, № 01 (2023): 290–96. http://dx.doi.org/10.31788/rjc.2023.1618029.

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The biological activities of extracts and isolated compounds of Macaranga mappa stem bark for antidiabetic herbal medicine, antioxidant, and cytotoxicity activities have been determined. The antidiabetic, antioxidant, and cytotoxicity activities of the sample were carried out by inhibition value of α-glucosidase, DPPH method, and brine shrimp larvae method, respectively. The initial methanol extract and its fractions have good activities against antidiabetics and antioxidants, except for the hexane fraction. The fractions with the highest activity for the antidiabetic and antioxidant tests wer

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Alqahtani, Ali S., Riaz Ullah, and Abdelaaty A. Shahat. "Bioactive Constituents and Toxicological Evaluation of Selected Antidiabetic Medicinal Plants of Saudi Arabia." Evidence-Based Complementary and Alternative Medicine 2022 (January 17, 2022): 1–23. http://dx.doi.org/10.1155/2022/7123521.

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The purpose of this review is to summarize the available antidiabetic medicinal plants in the Kingdom of Saudi Arabia with its phytoconstituents and toxicological findings supporting by the latest literature. Required data about medicinal plants having antidiabetic activities and growing in the Kingdom of Saudi Arabia were searched/collected from the online databases including Wiley, Google, PubMed, Google Scholar, ScienceDirect, and Scopus. Keywords used in search are in vivo antidiabetic activities, flora of Saudi Arabia, active ingredients, toxicological evaluations, and medicinal plants. A

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3

Gondokesumo, Marisca Evalina, Hanna Sari Widya Kusuma та Wahyu Widowati. "α-/β-Glucosidase and α-Amylase Inhibitory Activities of Roselle (Hibiscus sabdariffa L.) Ethanol Extract". Molecular and Cellular Biomedical Sciences 1, № 1 (2017): 34. http://dx.doi.org/10.21705/mcbs.v1i1.3.

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Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase involved in carbohydrate digestion. Thus, inhibition of these enzymes play important role in the treatment of diabetes mellitus. Roselle (Hibiscus sabdariffa L.) has been known to have several medicinal properties and potency as an antidiabetics agents. This reseacrh aimed to observe antidiabetic properties of roselle ethanol extract (REE) towar

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Tang, Xingli, Opeyemi J. Olatunji, Yifeng Zhou, and Xilin Hou. "Allium tuberosum : Antidiabetic and hepatoprotective activities." Food Research International 102 (December 2017): 681–89. http://dx.doi.org/10.1016/j.foodres.2017.08.034.

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Lena Ahmed Saleh Al-Faqeeh, Rafiuddin Naser, Kagne SR, and Subur W. Khan. "Activity of mushrooms against diabetic and inflammation: A review." GSC Biological and Pharmaceutical Sciences 14, no. 2 (2021): 037–44. http://dx.doi.org/10.30574/gscbps.2021.14.2.0035.

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Since ancient people, mushroom have been used as a source of food and in therapeutic remedies. Many recent studies confirm different biological activities of mushrooms which include antioxidant, antimicrobial, anticancer, antidiabetic and anti-inflammatory activities. Many mushroom species have been evaluated for their antidiabetic and anti-inflammatory activities. This study highlights the effectiveness of mushrooms as antidiabetic and anti-inflammatory agents.

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Lena, Ahmed Saleh Al-Faqeeh, Naser Rafiuddin, SR Kagne, and W. Khan Subur. "Activity of mushrooms against diabetic and inflammation: A review." GSC Biological and Pharmaceutical Sciences 14, no. 2 (2021): 037–44. https://doi.org/10.5281/zenodo.4605160.

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Since ancient people, mushroom have been used as a source of food and in therapeutic remedies. Many recent studies confirm different biological activities of mushrooms which include antioxidant, antimicrobial, anticancer, antidiabetic and anti-inflammatory activities. Many mushroom species have been evaluated for their antidiabetic and anti-inflammatory activities. This study highlights the effectiveness of mushrooms as antidiabetic and anti-inflammatory agents. 

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Muema, Felix Wambua, Consolata Nanjala, Millicent Akinyi Oulo, and Phurpa Wangchuk. "Phytochemical Content and Antidiabetic Properties of Most Commonly Used Antidiabetic Medicinal Plants of Kenya." Molecules 28, no. 20 (2023): 7202. http://dx.doi.org/10.3390/molecules28207202.

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Traditional medicinal plants have been used for decades in folk medicines in the treatment and management of several ailments and diseases including diabetes, pain, ulcers, cancers, and wounds, among others. This study focused on the phytochemical and antidiabetic activity of the commonly used antidiabetic medicinal species in Kenya. Phytochemical profiling of these species revealed flavonoids and terpenoids as the major chemical classes reported which have been linked with strong biological activities against the aforementioned diseases, among others. However, out of the selected twenty-two s

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Thapa, Chandra Bahadur, Anjana Bhattarai, Krishna Kumar Pant, Hari Datta Bhattarai, and Bijaya Pant. "Evaluation of Antioxidant, Antidiabetic, and Cytotoxic Activities of Lilium nepalense D. Don." Journal of Institute of Science and Technology 28, no. 2 (2023): 63–70. http://dx.doi.org/10.3126/jist.v28i2.61174.

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Lilium nepalense, a temperate medicinal plant, is used as a diuretic, antipyretic, tonic, flavoring agent, and heart pain treatment. This research aimed to evaluate the in vitro antioxidant and antidiabetic activities of the methanol, dichloromethane (DCM), and hexane fractions, and in vivo cytotoxic activities of the crude extracts of the bulb. The antioxidant activity was assessed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, antidiabetic activity by α-glucosidase inhibitory assay, and cytotoxic activity in terms of LC50 (median lethality concentration) by Brine shrimp assay. The DCM fracti

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Nurdin, Samsu Udayana, Siti Restia Salita, Celly Oktaviani, Subeki Subeki, and Novita Herdiana. "Aktivitas antidiabetes dan antioksidan pati jagung yang dikonjugasi dengan katekin [Antidiabetic and antioxidant activities of catechin conjugated corn starch]." Jurnal Teknologi & Industri Hasil Pertanian 28, no. 2 (2023): 129. http://dx.doi.org/10.23960/jtihp.v28i2.129-139.

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High levels of carbohydrate consumption, especially starch, are considered to be an important risk factor for diabetes mellitus (DM). Conjugation of starch with phenolic compounds those have antidiabetic activity such as catechin is suggested increase health benefit of the starch. Objective of this research was to find out optimal catechin concentration that was able to be conjugated into corn starch to produce conjugated starch with high antidiabetic and antioxidant properties. The synthesis of starch-catechin conjugates used free-radical grafting (FRG) by adding different concentration of ca

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Idris, Muddatstsir, Edwin Risky Sukandar, Adi Setyo Purnomo, Fahimah Martak, and Sri Fatmawati. "Antidiabetic, cytotoxic and antioxidant activities of Rhodomyrtus tomentosa leaf extracts." RSC Advances 12, no. 39 (2022): 25697–710. http://dx.doi.org/10.1039/d2ra03944c.

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As part of our project on exploring Indonesian medicinal plants for antidiabetic and anticancer agents, this study was conducted to investigate the total phenolic and flavonoid contents, and antioxidant, cytotoxic and antidiabetic properties of R. tomentosa leaf extracts.

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11

Idris, Muddatstsir, Adi Setyo Purnomo, Fahimah Martak, and Sri Fatmawati. "Antioxidant and Antidiabetic Activities of Melastoma Malabathricum Leaves Extracts." Journal of Hunan University Natural Sciences 49, no. 7 (2022): 144–53. http://dx.doi.org/10.55463/issn.1674-2974.49.7.16.

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Currently, no effective medication is available to treat diabetes despite this disease is a serious health problem. As part of our project to explore Indonesian medicinal plants for antidiabetic agents, this study aimed to investigate the total phenolic and flavonoid contents, antioxidant and antidiabetic properties of Melastoma malabathricum leaves extracts. Spectrophotometric methods were used to determine the total phenolic and flavonoid contents. Antioxidant activity was performed using DPPH, ABTS, and FRAP methods. The in vitro antidiabetic test was conducted through an inhibitory evaluat

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Do, Van Mai, Truong Han Le, Hong Phong Ngo, Phat Nguyen Phung, and Van Hung Mai. "A study on antidiabetic, and antibacterial activities of Leea rubra Blume." International Journal of Innovative Research and Scientific Studies 8, no. 1 (2025): 2533–43. https://doi.org/10.53894/ijirss.v8i1.5029.

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The current work investigated the antioxidant, antibacterial, and antidiabetic properties of extracts from Leea rubra roots, stems, and leaves in vitro. The antioxidant capabilities of Leea rubra extracts were tested using 2,2-diphenyl-1-picryl-hydrazyl, 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid), nitric oxide, total antioxidant activity, ferric reducing-antioxidant power, and reducing power tests. The extracts' antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli was tested using the agar-well diffusion method. The antidiabetic efficac

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Pattan, S. R., P. N, Kasar, B. D. Randale, et al. "SYNTHESIS AND EVALUATION OF SOME NOVEL 1, 3, 4-OXADIAZOLEDERIVATIVES FOR ANTIMICROBIAL AND ANTIDIABETIC ACTIVITIES." INDIAN DRUGS 50, no. 04 (2013): 39–45. http://dx.doi.org/10.53879/id.50.04.p0039.

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A series of 1, 3, 4-Oxadiazole derivatives have been synthesized and evaluated for antimicrobial and antidiabetic activities. The newly synthesized compounds have been characterized by IR, 1 H NMR and elemental analysis. All compounds have shown promising antimicrobial and antidiabetic activities when compared with standard drug ciprofloxacin and acarbose respectively. Compounds A2 ,B2 ,C1 ,D1 ,D2 ,E1 and E2 have shown promising antimicrobial activity while compounds A1 ,A2 ,B1 ,C1 ,D1 ,E1 and E2 have shown promising antidiabetic activity.

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Pattan, S. R., P. N, Kasar, B. D. Randale, et al. "SYNTHESIS AND EVALUATION OF SOME NOVEL 1, 3, 4-OXADIAZOLEDERIVATIVES FOR ANTIMICROBIAL AND ANTIDIABETIC ACTIVITIES." INDIAN DRUGS 50, no. 04 (2013): 39–45. http://dx.doi.org/10.53879/id.50.04.p0039.

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A series of 1, 3, 4-Oxadiazole derivatives have been synthesized and evaluated for antimicrobial and antidiabetic activities. The newly synthesized compounds have been characterized by IR, 1 H NMR and elemental analysis. All compounds have shown promising antimicrobial and antidiabetic activities when compared with standard drug ciprofloxacin and acarbose respectively. Compounds A2 ,B2 ,C1 ,D1 ,D2 ,E1 and E2 have shown promising antimicrobial activity while compounds A1 ,A2 ,B1 ,C1 ,D1 ,E1 and E2 have shown promising antidiabetic activity.

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M., Prabu, and Kumuthakalavalli R. "ANTIDIABETIC POTENTIAL OF THE OYSTER MUSHROOM PLEUROTUS FLORIDA (MONT.) SINGER." International Journal of Current Pharmaceutical Research 9, no. 4 (2017): 51. http://dx.doi.org/10.22159/ijcpr.2017v9i4.20765.

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Objective: The present investigation comprises, in vitro antidiabetic activity such as α-amylase and α-glucosidase inhibitory activities and in vivo antidiabetic activity of methanolic extract of Pleurotus florida.Methods: The fruiting bodies of Pleurotus florida were obtained from Mushroom Unit, Department of Biology, Gandhigram Rural Institute-Deemed University, Gandhigram, Dindigul, Tamil Nadu, India. Sample preparation, qualitative phytochemical analysis, in vitro antidiabetic activities namely α-amylase and α-glucosidase inhibitory activity and in vivo antidiabetic activity namely evaluat

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Habeebulla, M. Muhammed, and Malarkodi Velraj. "In vitro Antioxidant and Antidiabetic Activities of the Bark Extracts of Kandelia candel (L.) Druce." Asian Journal of Chemistry 34, no. 7 (2022): 1788–94. http://dx.doi.org/10.14233/ajchem.2022.23749.

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In present study, various extracts using different solvents such as petroleum ether, ethyl acetate and ethanol were subjected to in vitro antioxidant and antidiabetic activities. Ethanolic extract showed the highest activities in all antioxidant studies such as DPPH scavenging, ABTS scavenging and nitric oxide methods but it is comparatively weaker than standard drug ascorbic acid. In vitro antidiabetic activities were performed by using α-amylase and α-glucosidase inhibition in both method ethanolic extract showed highest activity, but the standard drug acarbose showed more potent than all ot

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Ali, Sajjad, Huaiji Zheng, Asma Zaidi, et al. "Moxifloxacin Metal Complexes: Synthesis, Characterisation, Antimicrobial and Antidiabetic Activities with Docking Studies." Bioinorganic Chemistry and Applications 2023 (January 3, 2023): 1–15. http://dx.doi.org/10.1155/2023/3754561.

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Six new metal complexes of Fe(III), Cu(II), and Hg(II) were synthesised, i.e., three (2, 4, and 5) with moxifloxacin (mono-ligand) and the other three (1, 3 and 6) with moxifloxacin and hydrazine (biligand). These were characterised through UV-Vis, FT-IR, elemental analysis (CHN), atomic absorption spectroscopy, TGA, scanning electron microscopy (SEM), and powder XRD studies. Further, all of these compounds were screened for their antimicrobial, cytotoxic, and antidiabetic potential. The study revealed that the synthesised metal complexes possess an excellent ability to become antifungal agent

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18

Alam, Fahmida, Md Asiful Islam, Mohammad Amjad Kamal, and Siew Hua Gan. "Updates on Managing Type 2 Diabetes Mellitus with Natural Products: Towards Antidiabetic Drug Development." Current Medicinal Chemistry 25, no. 39 (2019): 5395–431. http://dx.doi.org/10.2174/0929867323666160813222436.

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Over the years, natural products have shown success as antidiabetics in in vitro, in vivo studies and clinical trials. Because natural product-derived drugs are more affordable and effective with fewer side-effects compared to conventional therapies, pharmaceutical research is increasingly leaning towards the discovery of new antidiabetic drugs from natural products targeting pathways or components associated with type 2 diabetes mellitus (T2DM) pathophysiology. However, the drug discovery process is very lengthy and costly with significant challenges. Therefore, various techniques are current

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Vlachou, Evangelia-Eirini N., and Konstantinos E. Litinas. "An Overview on Pyranocoumarins: Synthesis and Biological Activities." Current Organic Chemistry 23, no. 24 (2020): 2679–721. http://dx.doi.org/10.2174/1385272823666191025151236.

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Pyrano- and dipyranocoumarins are classes of naturally occurring organic compounds with very interesting biological activities. This review focuses on the synthetic strategies for the synthesis of pyranocoumarins and dipyranocoumarins and the biological properties of those compounds. The synthesis involves the formation of the pyran ring, at first, from a coumarin or the formation of pyranone moiety from an existing pyran. Pyranocoumarins and dipyranocoumarins present anti-HIV, anti-cancer, neuroprotective, antidiabetic, antibacterial, antifungal, anti-inflammatory activities. Especially khell

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20

Ramachawolran Gobinath, Subramani Parasuraman, Subramaniam Sreeramanan, and Suresh V Chinni. "Antidiabetic and Antihyperlipidemic Activities of Methanolic Extract of Leaves of Coccinia grandis in Diabetic Rats." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 2324–31. http://dx.doi.org/10.26452/ijrps.v11ispl4.4460.

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Coccinia grandis is a one of the edible plant and its antidiabetic and antihyperlipidemic activities are not well explored. Hence, the present is planned to study the antidiabetic and antihyperlipidemic activities of methanolic extract of Coccinia grandis leaves in streptozotocin-induced diabetic rats. Coccinia grandis leaves was dried under the shade and extracted with methanol. Preliminary phytochemical and pharmacological analysis were conducted using methanolic extract of Coccinia grandis (MECG) leaves. Female Sprague dawley (SD) was used for acute toxicity studies. Female SD was induced w

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Hasbal, Gozde, Tugba Yilmaz Ozden, and Ayse Can. "In vitro Antidiabetic Activities of Two Sorbus Species." European Journal of Biology 76, no. 2 (2017): 57–60. http://dx.doi.org/10.5152/eurjbiol.2017.1710.

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22

Kumar, Sunil, Vipin Kumar, and Om Prakash. "Antidiabetic, Hypolipidemic, and Antioxidant Activities ofCallistemon lanceolatusLeaves Extract." Journal of Herbs, Spices & Medicinal Plants 17, no. 2 (2011): 144–53. http://dx.doi.org/10.1080/10496475.2011.583139.

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Hu, Weicheng, Mee-Jung Jung, Seong-Il Heo, and Myeong-Hyeon Wang. "Antioxidant and Antidiabetic Activities of Aralia elata Seeds." Journal of Applied Biological Chemistry 51, no. 3 (2008): 111–16. http://dx.doi.org/10.3839/jabc.2008.020.

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Mhaladi, R., I. T. Madamombe-Manduna, and S. S. Mashele. "Antidiabetic and cytotoxic activities of Aloe ferox Mill." South African Journal of Botany 103 (March 2016): 332. http://dx.doi.org/10.1016/j.sajb.2016.02.107.

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Siddiqui, Sadaf, Neetesh Kumar Jain, and Narendra Silawat. "Antidiabetic Activities of Extracts of Ficus bengalensis Linn." International Journal of Medical Sciences and Pharma Research 8, no. 2 (2022): 35–38. http://dx.doi.org/10.22270/ijmspr.v8i2.35.

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Abstract: Various extracts of diverse parts of medicinal plants have been shown to possess antidiabetic and hypoglycemic effect. Most of them look to act directly on pancreas (pancreatic effect) and stimulate insulin level in blood. Some have extra pancreatic effect by acting directly on tissues like liver, muscle, etc and alter favorably, the activities of the regulatory enzymes of glycolysis, gluconeogenesis and other pathways. The research work embodied in the thesis deals with the scientific exploration of indigenous plants viz., Ficus bengalensis Linn for their possible anti-diabetic and

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Samra, Reham M., Mohamed S. Darwish, Noha A. Abou-Zeid, Ebtihal Khojah, Vincent O. Imieje, and Ahmed A. Zaki. "Aurones as Antidiabetic Agents and Their Prebiotic Activities." Future Pharmacology 3, no. 3 (2023): 625–36. http://dx.doi.org/10.3390/futurepharmacol3030040.

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Cyperus conglomeratus has been utilized in traditional medicine as an emollient, diuretic, analgesic, anthelmintic, and for other diseases. Furthermore, several biological activities have been reported for the plant extract and the isolated metabolites. The chromatographic investigation of an ethyl acetate extract of the aerial parts led to the isolation of three aurone derivatives (1–3) from the plant for the first time. Their structures were identified as aureusidin (1), aureusidin-4-methyl ether (2), and 5-methyl aureusidin (3) using 1D and 2D NMR techniques, along with mass spectrometry. T

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Bhattarai, Bidhya, Lekha Nath Khanal, and Surya Kant Kalauni. "Antidiabetic and Antibacterial Activities of Syzygium cumini Seeds." Journal of Nepal Chemical Society 44, no. 1 (2024): 153–62. http://dx.doi.org/10.3126/jncs.v44i1.62689.

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Bioactive compounds of plants have been used in treating various diseases from ancient times. In this study, Syzygium cumini seed extract was studied for its antioxidant, antibacterial, and anti-diabetic potentials. The antioxidant potential was evaluated by DPPH assay. Whereas, the antibacterial feature was tested against Staphylococcus aureus, Escherichia coli, Salmonella typhi, and Klebsiella pneumonia by agar well diffusion method. The in vitro anti-diabetic potential was performed by the α-amylase enzyme inhibition method using CNPG3 (2-chloro-4-nitrophenyl-α-D-maltotriose) as a substrate

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Artanti, Nina, Faiza Maryani, Rizna Triana Dewi, et al. "in vitro Antidiabetic, Antioxidant and Cytotoxic Activities of Syzygium cumini Fractions from Leaves Ethanol Extract." Indonesian Journal of Cancer Chemoprevention 10, no. 1 (2019): 24. http://dx.doi.org/10.14499/indonesianjcanchemoprev10iss1pp24-29.

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Ethanol extract of Syzygium cumini (jamblang) leaves reveal its significant α-glucosidase inhibitory activity which perform the potential activity of this plant extract as antidiabetic agent. However, other bioactivities of this plant extract have been reported. The aim of current study was to evaluate the comparison of in vitro antidiabetic, antioxidant and cytotoxic activity of S. cumini fractions. The S. cumini leaves ethanol extract was fractionated by using column chromatography with n-hexane, ethyl acetate and methanol as eluents. Seven fractions were obtained from column chromatography

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Azab, Abdullatif. "Top Edible Wild Plants of Eastern Mediterranean Region. Part III: Antidiabetic Activity." European Journal of Medicinal Plants 34, no. 9 (2023): 84–107. http://dx.doi.org/10.9734/ejmp/2023/v34i91160.

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In the first two parts of this series of review articles, we presented the anticancer and anti-inflammatory activities of the most important wild edible plants of eastern Mediterranean region, which we named as the “Deca-plants” (D-P). In this review article, we will present the antidiabetic activities of these very important plants. Comparing with anticancer and anti-inflammatory activities, the overall antidiabetic activity of the D-P is moderate, but there are clear differences between the ten species. Based on this fact and on the knowledge that the D-P contain several natural products wit

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Shettar, Arun Kashivishwanath, and Ankala Basappa Vedamurthy. "STUDIES ON IN VITRO ANTIDIABETIC ACTIVITIES OF HOPEA PONGA AND VITEX LEUCOXYLON." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 2 (2017): 263. http://dx.doi.org/10.22159/ijpps.2017v9i2.16280.

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<p><strong>Objective: </strong>Evaluating antidiabetic property of <em>Hopea ponga</em> and <em>Vitex leucoxylon</em> extracts by using <em>in vitro</em> assays.</p><p><strong>Methods: </strong>The exhaustive serial extraction was carried out with a series of solvents: chloroform, ethyl acetate, methanol, ethanol and water with increasing polarity using Soxhlet apparatus. The concentrated and dried extracts were evaluated for antidiabetic activity by employing standard <em>in vitro</em> techniques (α-amyl

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Siripipatthana, Patthraporn, Muntana Nakornriab, Khanit Wangwasit, Aphidech Sangdee, and Ruttanachira Ruttanaprasert. "Optimizing Solvent Extraction for Potent Antioxidant and Antidiabetic Activities: A Study on Ampelocissus martini Root." Trends in Sciences 22, no. 1 (2024): 8998. http://dx.doi.org/10.48048/tis.2025.8998.

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The selection of extraction solvents is a critical factor influencing the composition and concentration of phytochemicals in plant extracts, thereby leading to variations in their biological activities. In this study, Ampelocissus martini Planch., an edible plant traditionally used for its medicinal properties, was investigated for its phytochemical profile and biological activities. We assessed the impact of different solvents used in fractionating the aqueous methanolic root extract of the plant on its phytochemical content, as well as its antioxidant, antidiabetic, and antibacterial propert

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Manguntungi, Baso, Dinar Suksmayu Saputri, Apon Zaenal Mustopa, et al. "Antidiabetic, Antioxidants and Antibacterial Activities of Lactic Acid Bacteria (LAB) from Masin (Fermented Sauce from Sumbawa, West Nusa Tenggara, Indonesia)." ANNALES BOGORIENSES 24, no. 1 (2020): 27. http://dx.doi.org/10.14203/ann.bogor.2020.v24.n1.27-34.

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The study aimed to determine the effectiveness of metabolites from Lactic Acid Bacteria (LAB) derived Masin (fermented sauce from Sumbawa) as antioxidant, antidiabetic, and antibacterial compounds. The LAB isolates were isolated from various strains of Staphylococcus piscifermentan which consisted of Staphylococcus piscifermentans strain CIP103958 (code: 2), strain BULST54 (code: 17), strain SK03 (code: 11), strain ATCC 51136 (code: 34), strain PCM 2409 (code: 28) and strain PU-87 (code: 5). The Metabolites of LAB were analyzed by the bioprospecting test to indicate antidiabetic, antioxidant a

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Anisah, Laela Nur, Wasrin Syafii, Gustan Pari, and Rita Kartika Sari. "Antidiabetic Activities and Identification of Chemical Compound from Samama (Anthocephalus macrophyllus (Roxb) Havil)." Indonesian Journal of Chemistry 18, no. 1 (2018): 66. http://dx.doi.org/10.22146/ijc.25492.

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Samama (Anthocephalus macrophyllus) is one of a pioneer indigenous fast growing species in Indonesia which have been used as traditional medicine for various diseases. The objectives were to determine the yield extract, to analyze their antidiabetic activity by inhibition assay for α-glucosidase enzyme activity and chemical analysis with GCMS. Extraction of leaves, bark and wood samples were done by using ethanol 95%. Fractionation the most active ethanol extract was conducted by using n-hexane and ethyl acetate. The yield of ethanol extracts in leaves, bark and wood were 13.90%, 12.87%, and 2

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Sivakumar, G., R. Sathish Kumar, P. Aruna, and Laksmana Perumal. "Antioxidant, Antimicrobial and Antidiabetic activities of Insulin plant rhizome extracts - A comparative study." Indian Journal of Pharmacy and Pharmacology 10, no. 2 (2023): 116–21. http://dx.doi.org/10.18231/j.ijpp.2023.024.

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retained the name as Insulin plant through traditional practice, further phytochemical and pharmacological evaluation of leaves of the plant has proven record on wider therapeutic potential such as antioxidant, antimicrobial and antidiabetic activity. Our interest of current research is to explore the rhizome by multiple extraction and to screen and find out the specific therapeutic potential of the specific extracts through relevant phytochemical and pharmacological evaluation. DPPH, Disc Diffusion and DNS methods were chosen to evaluate antioxidant and antibacterial and antidiabetic activity

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Tan, Minghui, Senlin Chang, Jianing Liu, et al. "Physicochemical Properties, Antioxidant and Antidiabetic Activities of Polysaccharides from Quinoa (Chenopodium quinoa Willd.) Seeds." Molecules 25, no. 17 (2020): 3840. http://dx.doi.org/10.3390/molecules25173840.

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Quinoa is known for its rich nutrients and bioactive compounds. In order to elucidate the preliminary structural characteristics and biological activity of polysaccharides from quinoa (QPs), five crude polysaccharides (QPE50, QPE60, QPE70, QPE80 and QPE90) were successively fractionated by gradient ethanol, and their physicochemical properties, antioxidant and antidiabetic activities were analyzed. The results implied that their total sugar contents were 52.82%, 63.69%, 67.15%, 44.56%, and 41.01%, and their weight-average molecular weights were 13,785 Da, 6489 Da, 4732 Da, 3318 Da, and 1960 Da

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Chigurupati, Sridevi, Shantini Vijayabalan, Arunkumar Karunanidhi, Kesavanarayanan Krishnan Selvarajan, Sitansu Sekhar Nanda, and Raghunath Satpathy. "Antidiabetic, antioxidant and in silico studies of bacterial endosymbiont inhabiting Nephelium lappaceum L." Ovidius University Annals of Chemistry 30, no. 2 (2019): 95–100. http://dx.doi.org/10.2478/auoc-2019-0017.

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Abstract Endophytes, notably obtaining attention, have been abided by potential origins of bioactive metabolites. In the acquaint study, endophyte was isolated from the leaves of Nephelium lappaceum L. The chosen endosymbiont was identified by 16s rRNA partial genome sequencing and investigated for their antioxidant and antidiabetic activities. A preliminary phytochemical test was comported for the affirmation of phytoconstituents in endophytic crude extract (NLM). Antioxidant activities were conducted by using 2-diphenyl-1-picrylhydrazyl (DPPH) method and 2,2′-azino-bis-3-ethylbenzthiazoline-

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Aditi, Dwivedi* Dr. N. P. S. Sengar Dr. Jitendra Banweer. "4-Thiazolidinone- A New Profile of Various Pharmacological Activities." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 854–68. https://doi.org/10.5281/zenodo.15598112.

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Thiazolidinone, a five-member heterocyclic compound involved in research aimed at evaluating new product that possess interesting biological activities and play vital role owing to its wide range of pharmacological activities like antibacterial, antifungal, antitubercular, anti-inflammatory, analgesic, anti-HIV, antidiabetic, anticancer, anticonvulsant, anthelmintic, insecticidal, hypnotic, amoebicidal, antipsychotic, antiparkinsonian, hypolipidemic and FSH agonist activity. The present review focuses on the development of 4-thiazolidinone with their potential activities.

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Tanriverdi, Başak, Ali Şen, Narin Sadıkoğlu, and Leyla Bitiş. "Bioactivity guided fractionation for investigation of antidiabetic activity on the different Origanum species from the Brevifilamentum section." Journal of Research in Pharmacy 29, no. 3 (2024): 1295–300. https://doi.org/10.12991/jrespharm.1712372.

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The aim of this study was to evaluate antidiabetic activities of Origanum bargyli (OB), Origanum haussknechtii (OH), Origanum rotundifolium (OR) species from Brevifilamentum section of genus Origanum and to investigate their roles in diabetes with the support of their antioxidant effects. Antidiabetic activities on OB, OH, and OR were investigated for the first time in the present study. DPPH and ABTS radicals scavenging, α-glucosidase inhibition methods were performed for antioxidant, antidiabetic activities, respectively. OB (12.70 and 32.62 μg/mL) and OR (10.61 and 32.28 μg/mL) exhibited st

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Pj, Jainey, and Ishwar Bhat K. "SYNTHESIS, IN SILICO PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES OF SOME PYRAZOLINE DERIVATIVES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 4 (2017): 456. http://dx.doi.org/10.22159/ajpcr.2017.v10i4.17093.

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Objectives: Nitrogen containing heterocyclic compounds plays an important role in medicinal chemistry. Among them, five-membered ring pyrazolines have found to possess many biological and pharmacological activities like anticancer, antitubercular, antimicrobial, anti-inflammatory etc. Objective is to determine the physicochemical and drug like properties of the synthesized pyrazolines by in silico methods and to screen their antidiabetic and antioxidant activities.Methods: Chalcones were synthesized from naphthaldehydes by condensing with various substituted acetophenones in ethanol and cycliz

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Oladipo, Mary Adelaide, Folasade Omobolanle Ajao, Adewusi John Adepoju, Kayode Taiwo Ishola, and Deborah Omowumi Afolabi. "Investigation of Antidiabetic Activities of Cu(II) Complex of Anacardium occidentale Leaves Crude Extract." Tanzania Journal of Science 49, no. 2 (2023): 311–21. http://dx.doi.org/10.4314/tjs.v49i2.3.

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Many synthetic chemical drugs have been widely used for the treatment of diabetes. However, many of these drugs are not locally available, are less effective, and are unaffordable for many diabetic patients in developing and underdeveloped countries. Therefore, in order to search for a locally available, effective, and cost-effective antidiabetic agent, this study synthesized the Cu(II) complex of crude leaf extract of Anacardium occidentale and investigated its antidiabetic activity in alloxan induced albino rats. The leaf crude extract and its metal complex were characterized using atomic ab

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Sai Harshini, Sura Ramesh, Deeksha Vijaykumar, Vennala Sadali Venugopal, et al. "Ethnomedicinal uses and pharmacological activities of scarlet gourd." Future Natural Products 10, no. 1 (2024): 39–43. https://doi.org/10.34172/fnp.169.

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Background and aims: Scarlet gourd, a common name for Coccinia grandis, is an essential plant due to its immense medicinal properties. It is traditionally used to treat bronchitis, cough, skin diseases, epilepsy, psoriasis, wound healing, smallpox, leprosy, gonorrhea, malaria, and jaundice. Methods: The scientific information on C. grandis was obtained from various sources, including Scopus, Google Scholar, PubMed, Science Direct, and other scientific databases, covering 2005 to 2022. Results: The bioactive components of C. grandis include taraxerone, lycopene, heptacosane, cephalandrine, lupe

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Zahan, Ronok, Laizuman Nahar, Zahangir Alam, Mst Luthfun Nesa, and M. Ekramul Haque. "Evaluation of Antidiarheal and Antidiabetic Activities of Wrigthia arborea (Dennst.) Mabb." Bangladesh Pharmaceutical Journal 16, no. 2 (2015): 211–16. http://dx.doi.org/10.3329/bpj.v16i2.22306.

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Wrigthia arborea (Dennst.) Mabb., locally known as Shet-kurchi, is a small deciduous tree. These species are important in the traditional healthcare, especially in menstrual and renal complaints. The present study was designed to investigate the antidiarheal and antidiabetic activities of methanol extract of W. arborea. The methanol extract was studied for antidiarrhoeal properties using castor oil and magnesium sulphate induced diarrhoeal model in mice. At the doses of 100 and 200 mg/kg body weight, the extract reduced the frequency and severity of diarrhea in test animals throughout the stud

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Famuyiwa, Samson O., Kayode Sanusi, Kolade O. Faloye, Yusuf Yilmaz, and Ümit Ceylan. "Antidiabetic and antioxidant activities: Is there any link between them?" New Journal of Chemistry 43, no. 34 (2019): 13326–29. http://dx.doi.org/10.1039/c9nj01251f.

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Ariviani, S., L. C. Sasmita, L. N. Khusafa'ah, N. Ratnaningsih, and A. Yulviatun. "Na-alginate elicitation as an alternative strategy to improve the antidiabetic potential of pigeon pea (Cajanus cajan) flour." Food Research 6, no. 4 (2022): 246–53. http://dx.doi.org/10.26656/fr.2017.6(4).843.

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Pigeon pea (Cajanus cajan) has been reported to exhibit antidiabetic activity such as hypoglycemic and hypocholesterolemic effects as well as antioxidant capacity in diabetichypercholesterolemia rats, alpha-glucosidase and alpha-amylase inhibitory activity, due to the bioactive compounds. Germination proved capable to increases the antidiabetic activity of pigeon pea. Elicitation has been known as a simple method for increasing the bioactive compounds and bioactivity of legumes sprouts. This study aimed to investigate the potential of Na-alginate elicitation in improving the antidiabetic activ

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Setiyawan, A., and A. Husni. "Antioxidant, antidiabetic activities and consumer acceptance of Sargassum hystrix tea combined with cinnamon powder." Food Research 6, no. 2 (2022): 159–65. http://dx.doi.org/10.26656/fr.2017.6(2).226.

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Sargassum hystrix is a species of brown seaweed containing bioactive compounds and has the potential to be used as a functional drink. This study was aimed to determine the fucoidan content, antioxidant, antidiabetic activities, and consumer acceptance rate of combining cinnamon powder to manufacture S. hystrix seaweed tea. The process was carried out by washing, drying, cutting, blending, weighing, roasting, and packaging the seaweed. Furthermore, the seaweed was tested to determine the total phenolic content, antioxidant (scavenging of hydroxyl radical and superoxide anion), antidiabetic (in

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Shukla, Abha, and Anchal Choudhary. "EVALUATION OF IN VITRO ANTIDIABETIC AND ANTI-INFLAMMATORY ACTIVITIES OF LEAVES EXTRACT OF BOEHMERIA RUGULOSA." Asian Journal of Pharmaceutical and Clinical Research 11, no. 9 (2018): 200. http://dx.doi.org/10.22159/ajpcr.2018.v11i9.25906.

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Objective: The objective of the study is to evaluate in vitro antidiabetic and anti-inflammatory activity of different extracts of leaves of Boehmeria rugulosa by different methods.Methods: In vitro α-glucose and α-amylase were used for antidiabetic activity and lipoxygenase, and protein denaturation method of inhibition assays was used to measure anti-inflammatory activity. Successive extraction of leaves petroleum ether (PE), chloroform (CH), ethyl acetate (EA), acetone (AC), and ethanol (ETH) was performed, and extracts obtained from the extraction were applicable to these activities.Result

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Zeba Masoom, Zeba Masoom, Sarita Sarita, and Dr Pooja Dr. Pooja. "Thiazolidinedione Derivatives: Multifaceted Pharmacological Activities and Therapeutic Potential." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 434–44. https://doi.org/10.35629/4494-1002434444.

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Thiazolidinediones are a class of well-established antidiabetic medications, similarly termed as glitazones. Thiazolidinedione structure has been a significant primary area of exploration, including plan and improvement of novel medications aimed at the administration of type 2 diabetes. Far reaching research has uncovered that the proposed antidiabetic movement in type II diabetes is because of their agonistic impact on peroxisome proliferator-initiated receptor (PPAR) having a place with the atomic receptor family. Glitazones have specific partiality to PPARγ. Pharmacology as well as science

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Nguyen, TheHan, ThiHuyen Nguyen, VanMinh Nguyen, et al. "Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea." Asian Pacific Journal of Tropical Biomedicine 9, no. 12 (2019): 501. http://dx.doi.org/10.4103/2221-1691.271723.

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Parasuraman, Subramani, Jasvin Singh, and Sathasivam Kathiresan. "Antioxidant and antidiabetic activities of methanolic extract ofCinnamomum cassia." Pharmacognosy Research 10, no. 3 (2018): 237. http://dx.doi.org/10.4103/pr.pr_162_17.

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Rodríguez, María, Masahisa Hasegawa, Freddy González-Mújica, et al. "Antidiabetic and antiradical activities of plants from Venezuelan Amazon." Revista Brasileira de Farmacognosia 18, no. 3 (2008): 331–38. http://dx.doi.org/10.1590/s0102-695x2008000300004.

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