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Journal articles on the topic 'Antidiabetic treatment'

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1

Muntean, Andrei Cătălin, Claudiu Morgovan, Smaranda Cosma, et al. "STUDY OF LIFE QUALITY AND TREATMENT SATISFACTION OF ROMANIAN DIABETIC PATIENTS." CBU International Conference Proceedings 7 (September 30, 2019): 771–77. http://dx.doi.org/10.12955/cbup.v7.1453.

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In Romania, antidiabetic medication is free, based on a program of the Ministry of Public Health: “Treatment of patients with diabetes mellitus”. Since October 1, 2006, antidiabetic drugs have been delivered through open circuit pharmacies in contractual relationship with the National Health Insurance House, after four years of centralized delivery through hospital pharmacies.
 Objectives: This study aims to describe the influences of the diabetes treatment regarding patients’ quality of life and their satisfaction.
 Methods: A cross-sectional descriptive study was performed in pharm
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2

Zhang, Jian, Rongyi Sun, Yang Cai, Bo Peng, Xi Yang, and Keming Gao. "Efficacy and Safety of Antidiabetic Agents for Major Depressive Disorder and Bipolar Depression: A Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Trials." Journal of Clinical Medicine 13, no. 4 (2024): 1172. http://dx.doi.org/10.3390/jcm13041172.

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Background: This meta-analysis aimed to determine the efficacy and safety of antidiabetic agents in the treatment of major depressive disorder and bipolar depression. Methods: Randomized controlled trials (RCTs) of antidiabetic agents in major depressive disorder or bipolar depression were searched in three electronic databases and three clinical trial registry websites from their inception up to October 2023. The differences in changes in the depression rating scale scores from baseline to endpoint or pre-defined sessions, response rate, remission rate, rate of side effects and dropout rate b
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3

Nana, Nurhasanah Rumanda, Khairunnisa, and Urip Harahap. "Potential Drug Interactions Of Oral Antidiabetic In Prescriptions Of Type 2 Diabetes Mellitus Patients At Kumpulan Pane Hospital." International Journal of Science, Technology & Management 2, no. 4 (2021): 1378–82. http://dx.doi.org/10.46729/ijstm.v2i4.278.

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 Diabetes Mellitus is a disease that can cause complications of other diseases so that the treatment to be given becomes more and this has the potential for interactions between drugs that can affect the physiological condition of the patient. The aim of this study is to analyze the potential of oral antidiabetic interactions on prescription at Kumpulan Pane Hospital. Analysis of potential oral antidiabetic interactions on a prescription using quantitative research methods is retrospective descriptive. Prescriptions used are inpatient and outpatient prescriptions for
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4

Maher, J. "Antidiabetic treatment for NASH?" Hepatology 33, no. 5 (2001): 1338–39. http://dx.doi.org/10.1053/jhep.2001.0331338.

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5

Zanchetti, Alberto. "Obesity, diabetes, and antidiabetic treatment." Journal of Hypertension 34, no. 2 (2016): 165–66. http://dx.doi.org/10.1097/hjh.0000000000000834.

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6

Aye, Myint Myint, and Paul Jennings. "Unit 5. Antidiabetic treatment options." Practice Nursing 22, no. 8 (2011): 1–8. http://dx.doi.org/10.12968/pnur.2011.22.8.cpd8.

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7

Vázquez, Citlali, Rusely Encalada, Isabel Jiménez-Galicia, et al. "Repurposing the Antidiabetic Drugs Glyburide, Gliquidone, and Glipizide in Combination with Benznidazole for Trypanosoma cruzi Infection." Pharmaceuticals 18, no. 1 (2024): 21. https://doi.org/10.3390/ph18010021.

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Infection with the protozoan parasite Trypanosoma cruzi causes human Chagas disease. Benznidazole (BNZ) and nifurtimox are the current drugs for the treatment; however, they induce severe adverse side effects in patients; therefore, there is a need to improve the treatment effectiveness and efficiency of these drugs for its safer use. Background/Objective: Glyburide, glipizide, and gliquidone, hypoglycemic drugs for diabetes treatment, were previously predicted to bind to dihydrofolate reductase-thymidylate synthase from T. cruzi by in silico docking analysis; they also showed antiproliferativ
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8

Locatelli, Anna, Sara Ornaghi, Alessandra Terzaghi, et al. "Antidiabetic Therapy during Pregnancy: The Prescription Pattern in Italy." International Journal of Environmental Research and Public Health 20, no. 23 (2023): 7139. http://dx.doi.org/10.3390/ijerph20237139.

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Pregestational and gestational diabetes mellitus are relevant complications of pregnancy, and antidiabetic drugs are prescribed to obtain glycemic control and improve perinatal outcomes. The objective of this study was to describe the prescription pattern of antidiabetics before, during and after pregnancy in Italy and to evaluate its concordance with the Italian guideline on treatment of diabetes mellitus. A multi-database cross-sectional population study using a Common Data Model was performed. In a cohort of about 450,000 women, the prescribing profile of antidiabetics seemed to be in line
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9

COMAN, Cristina, Olivia Dumitrita RUGINA, and Carmen SOCACIU. "Plants and Natural Compounds with Antidiabetic Action." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 40, no. 1 (2012): 314. http://dx.doi.org/10.15835/nbha4017205.

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Diabetes has become the most common metabolic disease worldwide. In particular, type 2 diabetes is the most commonly encountered type of diabetes, which is characterised by the inability of the organism to respond to normal levels of circulating insulin, also called insulin resistance. Current antidiabetic therapy is based on synthetic drugs that very often have side effects. For this reason, there is a continuous need to develop new and better pharmaceuticals as alternatives for the management and treatment of the disease. Natural hypoglycaemic compounds may be attractive alternatives to synt
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10

Mohsen, Amira Mohamed. "Nanotechnology Advanced Strategies for the Management of Diabetes Mellitus." Current Drug Targets 20, no. 10 (2019): 995–1007. http://dx.doi.org/10.2174/1389450120666190307101642.

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Background:Medications currently available for the management of diabetes mellitus are inconvenient and have some limitations. Thus, investigations for novel approaches are needed to deliver and target antidiabetics safely to the site of action.Objective:The present review emphasizes the limitations of conventional antidiabetics and provides the recent progresses of nanotechnology in the treatment of diabetes mellitus with a special highlight on the novel nanocarriers methodologies employed as antidiabetic drug delivery systems.Methods:The potential nanocarriers employed for the treatment of d
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11

Alqahtani, Ali S., Riaz Ullah, and Abdelaaty A. Shahat. "Bioactive Constituents and Toxicological Evaluation of Selected Antidiabetic Medicinal Plants of Saudi Arabia." Evidence-Based Complementary and Alternative Medicine 2022 (January 17, 2022): 1–23. http://dx.doi.org/10.1155/2022/7123521.

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The purpose of this review is to summarize the available antidiabetic medicinal plants in the Kingdom of Saudi Arabia with its phytoconstituents and toxicological findings supporting by the latest literature. Required data about medicinal plants having antidiabetic activities and growing in the Kingdom of Saudi Arabia were searched/collected from the online databases including Wiley, Google, PubMed, Google Scholar, ScienceDirect, and Scopus. Keywords used in search are in vivo antidiabetic activities, flora of Saudi Arabia, active ingredients, toxicological evaluations, and medicinal plants. A
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Lai, Bun-Yueh, Tzung-Yan Chen, Shou-Hsien Huang та ін. "Bidens pilosaFormulation Improves Blood Homeostasis andβ-Cell Function in Men: A Pilot Study". Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/832314.

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B. pilosahas long been purported to have antidiabetes activity, but despite the advancement in phytochemistry and animal models of diabetes, no human clinical trials have been conducted to date. Here, we evaluated the effect of aB. pilosaformulation on fasting blood glucose (FBG), fasting serum insulin, and glycosylated hemoglobin A1c(HbA1c)in diabetic subjects. TheB. pilosaformulation reduced the level of FBG andHbA1cin diabetics but increased fasting serum insulin in healthy subjects. Moreover, combination ofB. pilosaformulation with antidiabetic drugs had better glycemic control in diabetic
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13

Magkou, Dimitra, and Konstantinos Tziomalos. "Antidiabetic treatment, stroke severity and outcome." World Journal of Diabetes 5, no. 2 (2014): 84. http://dx.doi.org/10.4239/wjd.v5.i2.84.

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14

Abbatecola, Angela Marie, Giuseppe Paolisso, Andrea Corsonello, Silvia Bustacchini, and Fabrizia Lattanzio. "Antidiabetic Oral Treatment in Older People." Drugs & Aging 26, Supplement 1 (2009): 53–62. http://dx.doi.org/10.2165/11534660-000000000-00000.

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15

Mathieu, Chantal. "Liraglutide – A Once-daily Human Glucagon-like Peptide-1 Analogue Treatment for Type 2 Diabetes." European Endocrinology 05 (2009): 38. http://dx.doi.org/10.17925/ee.2009.05.00.38.

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Type 2 diabetes is a progressive disease characterised by deteriorating β-cell function and glycaemic control. To counter this, affected individuals require regular intensification of their antidiabetes treatments to provide appropriate metabolic control. However, current treatment options – such as sulphonylureas, thiazolidinediones and insulins – induce weight gain, which can reduce patient acceptance and/or compliance with treatment and may have significant health implications. In addition, many of the antidiabetic therapies raise the risk of hypoglycaemic episodes. Therefore, patients, phy
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16

Pujilestari, Mardiana, Arina Titami, and Sugiyono Sugiyono. "The Relationship Between Oral Antidiabetic Treatment And Blood Sugar Level Among Type 2 Diabetes Mellitus Patients in Nur Hidayah Hospital Yogyakarta." Disease Prevention and Public Health Journal 19, no. 1 (2025): 52–58. https://doi.org/10.12928/dpphj.v19i1.11948.

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Background: Diabetes mellitus is a chronic disease that poses a global health threat, with type 2 diabetes mellitus accounts for 90% of all cases. In Indonesia, diabetes mellitus is among the causes of high mortality due to non-communicable diseases. If not treated properly, type 2 diabetes mellitus can lead to various complications, potentially worsening the patient's condition. To address this, blood glucose levels must be controlled through the use of oral antidiabetic medications, either as monotherapy or in combination therapy. This study aims to the accuracy of oral antidiabetic drugs us
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17

Rajjoub Al-Mahdi, Ez Alddin, Vivencio Barrios, and Jose L. Zamorano. "Metformin in the era of new antidiabetics." Future Cardiology 17, no. 3 (2021): 475–85. http://dx.doi.org/10.2217/fca-2020-0195.

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Type II diabetes mellitus is a known cardiovascular risk factor and its prevalence continues to increase. A revolution in the Type II diabetes mellitus treatment has occurred with the arrival of new antidiabetic drugs, which are thought to compromise metformin place. We aim to review the pharmacology, available evidence and clinical aspects of metformin use in the era of new antidiabetics.
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Saldi, Andini Putri, and Yusni Atifah. "Literature Review: Potensi Tanaman Serai (Cymbopogon Citratus) sebagai Antidiabetes." MASALIQ 4, no. 2 (2024): 488–97. http://dx.doi.org/10.58578/masaliq.v4i2.2725.

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The World Health Organization (WHO) explains that more than 220 million people worldwide have diabetes mellitus. Diabetes mellitus is a chronic metabolic disorder caused by not producing enough insulin. Treatment of DM is costly and often has side effects that can be detrimental to the body. Therefore, traditional medicine using herbal plants has begun to be developed at this time. A plant that has the potential as an antidiabetic is lemongrass. This study aims to determine the potential of lemongrass plants as antidiabetics. The method used in writing this article is Literature Review Article
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Janhavi, Chaudhari* Dr. Prashant Malpure Rahul Arote Dr. Gokul Talele. "Floating Microspheres in Diabetes Treatment: A Comprehensive Review." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1709–17. https://doi.org/10.5281/zenodo.15046943.

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Blood glucose control is necessary for the management of diabetes mellitus, and this frequently calls for taking many daily doses of antidiabetic medications. Offering enhanced bioavailability and extended drug release, floating microspheres have emerged as a viable gastroretentive drug delivery technology for antidiabetic medications. Among the most common types, floating microspheres have several advantages. To prevent the impulses of gastric emptying and release the medication for an extended amount of time, they disperse evenly throughout the gastric fluid. Because of their ability to floa
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20

Ogura, Jiro, and Hiroaki Yamaguchi. "The Effectiveness of Antidiabetic Drugs in Treating Dementia: A Peek into Pharmacological and Pharmacokinetic Properties." International Journal of Molecular Sciences 23, no. 12 (2022): 6542. http://dx.doi.org/10.3390/ijms23126542.

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Dementia dramatically affects the activities of daily living and quality of life; thus, many therapeutic approaches for overcoming dementia have been developed. However, an effective treatment regimen is yet to be developed. As diabetes is a well-known risk factor for dementia, drug repositioning and repurposing of antidiabetic drugs are expected to be effective dementia treatments. Several observational studies have been useful for understanding the effectiveness of antidiabetic drugs in treating dementia, but it is difficult to conclusively analyze the association between antidiabetic drug t
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Alam, Fahmida, Md Asiful Islam, Mohammad Amjad Kamal, and Siew Hua Gan. "Updates on Managing Type 2 Diabetes Mellitus with Natural Products: Towards Antidiabetic Drug Development." Current Medicinal Chemistry 25, no. 39 (2019): 5395–431. http://dx.doi.org/10.2174/0929867323666160813222436.

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Over the years, natural products have shown success as antidiabetics in in vitro, in vivo studies and clinical trials. Because natural product-derived drugs are more affordable and effective with fewer side-effects compared to conventional therapies, pharmaceutical research is increasingly leaning towards the discovery of new antidiabetic drugs from natural products targeting pathways or components associated with type 2 diabetes mellitus (T2DM) pathophysiology. However, the drug discovery process is very lengthy and costly with significant challenges. Therefore, various techniques are current
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22

Savych, Alona, Svetlana Marchyshyn, and Roksolana Basaraba. "Determination of fatty acid composition content in the herbal antidiabetic collections." Pharmacia 67, no. 3 (2020): 153–59. http://dx.doi.org/10.3897/pharmacia.67.e51812.

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It was determined the qualitative composition and the quantitative content of fatty acids in the herbal antidiabetic collection № 3, № 4, № 7, № 13, № 19, which are used in folk medicine for prevention and treatment of diabetes mellitus type 2 in Ukraine by GC/MS method. According to the results it was identified 8 fatty acids in the herbal antidiabetic collection № 3, 13 fatty acids in the herbal antidiabetic collection № 4, 12 fatty acids in the herbal antidiabetic collection № 7, 13 fatty acids in the herbal antidiabetic collection № 13 and 11 fatty acids in the herbal antidiabetic collecti
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Savych, Alona, Svetlana Marchyshyn, and Roksolana Basaraba. "Determination of fatty acid composition content in the herbal antidiabetic collections." Pharmacia 67, no. (3) (2020): 153–59. https://doi.org/10.3897/pharmacia.67.e51812.

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It was determined the qualitative composition and the quantitative content of fatty acids in the herbal antidiabetic collection № 3, № 4, № 7, № 13, № 19, which are used in folk medicine for prevention and treatment of diabetes mellitus type 2 in Ukraine by GC/MS method. According to the results it was identified 8 fatty acids in the herbal antidiabetic collection № 3, 13 fatty acids in the herbal antidiabetic collection № 4, 12 fatty acids in the herbal antidiabetic collection № 7, 13 fatty acids in the herbal antidiabetic collection № 13 and 11 fatty acids in the herbal antidiabetic collecti
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24

Michailidis, Michalis, Despina A. Tata, Despina Moraitou, et al. "Antidiabetic Drugs in the Treatment of Alzheimer’s Disease." International Journal of Molecular Sciences 23, no. 9 (2022): 4641. http://dx.doi.org/10.3390/ijms23094641.

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The public health burden of type 2 diabetes mellitus and Alzheimer’s disease is steadily increasing worldwide, especially in the population of older adults. Epidemiological and clinical studies suggest a possible shared pathophysiology between the two diseases and an increased risk of AD in patients with type 2 diabetes mellitus. Therefore, in recent years, there has been a substantial interest in identifying the mechanisms of action of antidiabetic drugs and their potential use in Alzheimer’s disease. Human studies in patients with mild cognitive impairment and Alzheimer’s disease have shown
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Gondokesumo, Marisca Evalina, Hanna Sari Widya Kusuma та Wahyu Widowati. "α-/β-Glucosidase and α-Amylase Inhibitory Activities of Roselle (Hibiscus sabdariffa L.) Ethanol Extract". Molecular and Cellular Biomedical Sciences 1, № 1 (2017): 34. http://dx.doi.org/10.21705/mcbs.v1i1.3.

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Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase involved in carbohydrate digestion. Thus, inhibition of these enzymes play important role in the treatment of diabetes mellitus. Roselle (Hibiscus sabdariffa L.) has been known to have several medicinal properties and potency as an antidiabetics agents. This reseacrh aimed to observe antidiabetic properties of roselle ethanol extract (REE) towar
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Ojetunde, A. O. "ANTIDIABETIC EFFECTS OF MEDICINAL PLANTS." Eastern Ukrainian Medical Journal 9, no. 1 (2021): 1–17. http://dx.doi.org/10.21272/eumj.2021;9(1):1-17.

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Diabetes is a chronic disorder that is characterized by an increase in blood glucose (hyperglycemia) with alteration of protein, carbohydrates, and fat metabolism. Consequently, it can lead to renal failure, atherosclerosis, nerve damage, blindness, and coronary heart disease. It is also known as the 5th leading cause of death. Although, there are numerous types of glucose-lowering drugs that exhibit anti-diabetic effects but results of treatment in patients are still not so perfect. Therefore, many treatments that include the use of medicinal plants are suggested and encouraged. Medical plant
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27

Argitis, P., A. Karampas, P. Bringiotti, S. Karavia, O. Pikou, and F. E. Kakavitsas. "A novel approach to patients with schizophrenia and type 2 diabetes showing low treatment compliance." European Psychiatry 65, S1 (2022): S768. http://dx.doi.org/10.1192/j.eurpsy.2022.1983.

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Introduction Patients with schizophrenia usually demonstrate low compliance to medication. This could be a component of the disorder or a fact that they are not being properly cared. Objectives To prevent this in, we tried to treat these patients with long term action antidiabetic agents, in order to achieve better compliance. Methods HbA1C measurements of patients suffering from schizophrenia and at the same time receiving oral antidiabetic treatment were conducted. 62 patients were found that fell under the criteria of non regulated type 2 diabetes and at the same time presented less than 70
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Spasov, Alexander A., Vadim A. Kosolapov, Denis A. Babkov, and Olga Yu Mayka. "Glucokinase activators — a promising class of antidiabetic drugs." Problems of Endocrinology 64, no. 3 (2018): 180–87. http://dx.doi.org/10.14341/probl8747.

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Type 2 diabetes mellitus is an urgent problem of the modern healthcare. Despite a wide choice of oral hypoglycemic drugs, today there is a great need to create and introduce into clinical practice new, effective, and safe drugs for the treatment of diabetes. One of the promising targets for the creation of new antidiabetics is a glucokinase. It has an exceptionally high influence on glucose homeostasis, serving as a glucose “sensor” in pancreatic β-cells and controlling the rate of glycogen synthesis in the liver. In the present work, the molecular-genetic structure of the enzyme, as well as i
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Lakshman, Miss Ghodake Rutuja. "Guduchi is Powder Dosage Form is used in Treatment of Diabetics Mellitus." International Journal for Research in Applied Science and Engineering Technology 9, no. 12 (2021): 1385–93. http://dx.doi.org/10.22214/ijraset.2021.39493.

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Abstract: Guduchi is one of the most versatile rejuvenating herb, possessing numerous therapeutic attributes. Madhumehahara (Antidiabetic) properties of Guduchi are highly appreciated in Ayurveda and even in recent modern researches. Scattered information pertaining to antidiabetic role of Tinospora is accessible inAyurvedic literature and there is need to assemble it. Present review Present review encompasses indepth information of antidiabetic potential of Guduchi and its various dosage forms from Ayurvedic view and to understand the possible mechanism of its action in combating the complex
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Nandikola, Jaya Raju, Sandesh Rangnath Wayal, Vijayabanu S., et al. "Antidiabetic Management Strategies for Treatment of Polycystic Ovarian Syndrome." Journal of Neonatal Surgery 14, no. 1S (2025): 192–209. https://doi.org/10.52783/jns.v14.1517.

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Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder characterized by metabolic and reproductive dysfunctions, with insulin resistance playing a central role. Antidiabetic drugs, particularly insulin sensitizers such as metformin, are essential in managing both metabolic and reproductive aspects of PCOS. This article explores the effectiveness of antidiabetic medications in PCOS management, focusing on metformin, GLP-1 receptor agonists, and DPP-4 inhibitors. The integration of these pharmacological agents with hormonal therapies, such as oral contraceptives, offers a comprehen
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Suardiana, I. Kadek, Dwi Endarti, and Tuangrat Phodha. "Cost-effectiveness analysis of Oral Semaglutide treatment for type 2 diabetes mellitus patients: a systematic review." Journal of Public Health and Development 22, no. 3 (2024): 272–88. http://dx.doi.org/10.55131/jphd/2024/220322.

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GLP-1 is a new generation of antidiabetics recommended by the American Diabetes Association and European Association for the study of diabetes as an add-on therapy for metformin when therapeutic purposes are not achieved. In this context, oral Semaglutide received FDA approval in September 2019 to be used alongside dietary and exercise regimens to enhance glycemic management in adults diagnosed with type 2 diabetes mellitus (T2DM). Therefore, this systematic review aimed to analyze cost-effectiveness of oral Semaglutide compared to other antidiabetics and/or injectable GLP-1 within the same gr
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Puspitasari, Vina, and Nisrina Choerunisa. "Kajian Sistematik : Efek Anti Diabetes Buah Pare (Momordica charantia Linn.) Terhadap Kadar Glukosa Darah pada Tikus yang Diinduksi Aloksan." Generics: Journal of Research in Pharmacy 1, no. 2 (2021): 18–27. http://dx.doi.org/10.14710/genres.v1i2.11052.

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ABSTRAKBuah Pare merupakan salah satu tanaman tradisional yang memiliki senyawa aktif untuk menurunkan kadar glukosa darah. Penelitian ini bertujuan untuk mengidentifikasi efek anti diabetes buah pare (Momordica charantia Linn.) terhadap kadar glukosa darah pada tikus yang diinduksi aloksan. Pencarian secara komprehensif pada 3 database (Pubmed, Scopus, dan Google Scholar) dari tahun 2011-2021. Data yang diekstraksi dari setiap artikel penelitian meliputi identitas artikel (nama peneliti dan tahun penelitian), subjek, tipe preparasi, pelarut ekstraksi, dosis yang digunakan, durasi perlakuan, h
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Cipriani, Cristiana, Gabriella Lauriero, Giovanni Tripepi, et al. "Effect of Antidiabetic Drugs on Bone Health in Patients with Normal Renal Function and in Chronic Kidney Disease (CKD): Insight into Clinical Challenges in the Treatment of Type 2 Diabetes." Journal of Clinical Medicine 12, no. 23 (2023): 7260. http://dx.doi.org/10.3390/jcm12237260.

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Among the metabolic changes occurring during the course of type 2 diabetes (T2DM) and diabetic kidney disease (DKD), impaired bone health with consequent increased fracture risk is one of the most complex and multifactorial complications. In subjects with diabetic kidney disease, skeletal abnormalities may develop as a consequence of both conditions. In the attempt to define a holistic approach to diabetes, potential effects of various classes of antidiabetic drugs on the skeleton should be considered in the setting of normal kidney function and in DKD. We reviewed the main evidence on these s
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Sultan, Khushbakht, Muhammad Zakir, Haroon Khan, et al. "The Effect of Extract/Fractions of Caralluma tuberculata on Blood Glucose Levels and Body Weight in Alloxan-Induced Diabetic Rabbits." Journal of Evidence-Based Complementary & Alternative Medicine 19, no. 3 (2014): 195–99. http://dx.doi.org/10.1177/2156587214531019.

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Caralluma tuberculata is a cooked food item in Pakistan especially for diabetics. The current study was designed to explore the antidiabetic potential of extract/fractions of Caralluma tuberculata in alloxan-induced diabetic rabbits and its effect on body weight. The crude extract of the plant provoked 24% and 44% antidiabetic action at 25 and 50 mg/kg OP, respectively, after the 24th day of treatment, which was strongly supported by a positive effect on the body weight of animals. On fractionation, pretreatment of the ethyl acetate fraction demonstrated most dominant (25.17% and 34.83%) antid
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Muema, Felix Wambua, Consolata Nanjala, Millicent Akinyi Oulo, and Phurpa Wangchuk. "Phytochemical Content and Antidiabetic Properties of Most Commonly Used Antidiabetic Medicinal Plants of Kenya." Molecules 28, no. 20 (2023): 7202. http://dx.doi.org/10.3390/molecules28207202.

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Traditional medicinal plants have been used for decades in folk medicines in the treatment and management of several ailments and diseases including diabetes, pain, ulcers, cancers, and wounds, among others. This study focused on the phytochemical and antidiabetic activity of the commonly used antidiabetic medicinal species in Kenya. Phytochemical profiling of these species revealed flavonoids and terpenoids as the major chemical classes reported which have been linked with strong biological activities against the aforementioned diseases, among others. However, out of the selected twenty-two s
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Palanisamy, U. D., and T. Manaharan. "SYZYGIUM AQUEUM LEAF EXTRACTS FOR POSSIBLE ANTIDIABETIC TREATMENT." Acta Horticulturae, no. 1098 (September 2015): 13–22. http://dx.doi.org/10.17660/actahortic.2015.1098.1.

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Vargas Delgado, Ariana P., Juan Antonio Requena Ibañez, Carlos G. Santos-Gallego, and Juan Jose Badimon. "Are the antidiabetic SGLT2 inhibitors a cardiovascular treatment?" Clínica e Investigación en Arteriosclerosis (English Edition) 33, no. 1 (2021): 33–40. http://dx.doi.org/10.1016/j.artere.2020.12.004.

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38

Colagiuri, S. "CONCOMITANT ANTIHYPERTENSIVE AND ANTIDIABETIC TREATMENT: FRIENDS OR FOE?" Journal of Hypertension 29 (June 2011): e285. http://dx.doi.org/10.1097/00004872-201106001-00808.

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Takahara, Mitsuyoshi, Toshihiko Shiraiwa, Naoto Katakami, Taka-aki Matsuoka, and Iichiro Shimomura. "Once-weekly oral antidiabetic agent and treatment satisfaction." Current Medical Research and Opinion 33, no. 11 (2017): 2093–94. http://dx.doi.org/10.1080/03007995.2017.1359519.

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Gantz, Ira. "Once-weekly oral antidiabetic agent and treatment satisfaction." Current Medical Research and Opinion 33, no. 11 (2017): 2095. http://dx.doi.org/10.1080/03007995.2017.1359520.

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Kuzio, Agnieszka, Aleksandra Cieplińska, and Kinga Ziojła-Lisowska. "Antidiabetic drugs as the future of obesity treatment." Quality in Sport 17 (July 21, 2024): 53077. http://dx.doi.org/10.12775/qs.2024.17.53077.

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Obesity is a multifactorial chronic disease with complex pathogenesis. Its causes are considered to be genetic, biological, epigenetic, environmental, developmental and behavioral factors leading to excessive caloric intake and, consequently, weight gain. As body weight increases, the risk of developing many chronic diseases increases and, as a result, life expectancy decreases. The basis of obesity treatment is the introduction of changes in behavior and lifestyle modification, based primarily on the adoption of a healthy, balanced diet with a caloric deficit, regular physical activity and li
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Sumida, Yoshio, Masashi Yoneda, Katsutoshi Tokushige, et al. "Antidiabetic Therapy in the Treatment of Nonalcoholic Steatohepatitis." International Journal of Molecular Sciences 21, no. 6 (2020): 1907. http://dx.doi.org/10.3390/ijms21061907.

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Liver-related diseases are the third-leading causes (9.3%) of mortality in type 2 diabetes (T2D) in Japan. T2D is closely associated with nonalcoholic fatty liver disease (NAFLD), which is the most prevalent chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH), a severe form of NAFLD, can lead to hepatocellular carcinoma (HCC) and hepatic failure. No pharmacotherapies are established for NASH patients with T2D. Though vitamin E is established as a first-line agent for NASH without T2D, its efficacy for NASH with T2D recently failed to be proven. The effects of pioglitazone on N
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Benito, D. González, R. Escobar Conesa, C. Sánchez Ovejero, et al. "Acute hepatitis by antidiabetic treatment: A case report." Clinica Chimica Acta 493 (June 2019): S218—S219. http://dx.doi.org/10.1016/j.cca.2019.03.452.

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Adeleye, Oluwafunbi Christianah, and Ida Masana Risenga. "The In Vitro Assessment of Antidiabetic Activity of the Plant Extracts Obtained from Portulacaria afra Jack. Grown under Concurrent Extreme Temperatures and Water-deficit Conditions." Biomedical and Pharmacology Journal 17, no. 1 (2024): 309–22. http://dx.doi.org/10.13005/bpj/2859.

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The escalating global prevalence of diabetes mellitus presents a significant health concern, prompting exploration into alternative treatments. Recent research highlights the efficacy of newly developed bioactive medications sourced from plants in managing diabetes, surpassing currently used oral hypoglycemic drugs. Medicinal plants' therapeutic characteristics are from secondary metabolites and are greatly influenced by environmental factors. This study investigated the antidiabetic properties of Portulacaria afra, using various extraction solvents under different temperature settings with wa
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Kalkan, Ahmet Toygar, Goknur Yorulmaz, Aysen Akalin, and Ener Cagri Dinleyici. "Intestinal Microbiota Composition in Patients with Type 2 Diabetes and Effects of Oral Antidiabetics." Journal of Clinical Medicine 14, no. 8 (2025): 2786. https://doi.org/10.3390/jcm14082786.

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Introduction: The cause–effect relationships between microbiota composition changes and type 2 diabetes (T2D) are complex, likely involving two-way interactions, and require further elucidation. Few studies have examined the interactions of antidiabetic drugs with the gut microbiota. This study’s goal was to evaluate the gut microbiota of patients with type 2 diabetes at first diagnosis and again after 12 weeks of taking oral antidiabetic drugs. Methods: We performed a fecal microbiota analysis of adult patients who recently received a T2D diagnosis and healthy adults. We compared the microbio
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Thadhani, Vinitha M., and Veranja Karunaratne. "Potential of Lichen Compounds as Antidiabetic Agents with Antioxidative Properties: A Review." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/2079697.

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The advancement in the knowledge of potent antioxidants has uncovered the way for greater insight in the treatment of diabetic complications. Lichens are a rich resource of novel bioactive compounds and their antioxidant potential is well documented. Herein we review the antidiabetic potential of lichens which have received considerable attention, in the recent past. We have correlated the antidiabetic and the antioxidant potential of lichen compounds. The study shows a good accordance between antioxidant and antidiabetic activity of lichens and points out the need to look into gathering the s
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Staff, Editorial. "Comparative Antidiabetic Effects of Five Medicinal Plants." Phytopharmacological Communications 3, no. 2 (2023): 77–80. http://dx.doi.org/10.55627/ppc.003.02.0470.

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Kukavica and colleagues examined the antidiabetic, antioxidant, and antimicrobial properties of ethanol extracts of five medicinal plants, Salvia officinalis, Trifolium pratense, Agrimonia eupatoria, Cichorium intybus, and Vinca minor for their possible use in the treatment of type 2 diabetes (T2D). It was found that A. eupatoria extract contains the highest percentage of flavonoids and showed excellent antidiabetic, antioxidant, and antimicrobial activity. Their study revealed that S. officinalis extract contains slightly fewer flavonoids and showed weaker antidiabetic activity but stronger a
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Abu-Odeh, Alaa M., and Wamidh H. Talib. "Middle East Medicinal Plants in the Treatment of Diabetes: A Review." Molecules 26, no. 3 (2021): 742. http://dx.doi.org/10.3390/molecules26030742.

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Diabetes is a global health problem, and the number of diabetic patients is in continuous rise. Conventional antidiabetic therapies are associated with high costs and limited efficiency. The use of traditional medicine and plant extracts to treat diabetes is gaining high popularity in many countries. Countries in the Middle East region have a long history of using herbal medicine to treat different diseases, including diabetes. In this review, we compiled and summarized all the in vivo and in vitro studies conducted for plants with potential antidiabetic activity in the Middle East region. Pla
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Obet, Obet, Johnly A. Rorong, and Feti Fatimah. "Skrining Fitokimia dan Aktivitas Antidiabetes dalam Ekstrak Daun Nasi (Phrynium capitatum)." Jambura Journal of Chemistry 2, no. 2 (2020): 53–61. http://dx.doi.org/10.34312/jambchem.v2i2.7083.

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Research about phytochemical screening and antidiabetic activity inside rice leaf extract (phrynium
 capitatum) had been conducted. Objective of this research was to find phytochemical and antidiabetic activity
 inside rice leaf extract. Research Methodology used for phytochemical screening was testting of alkaloids,
 phenolics, flavonoids, saponins, steroids and triterpenoids. While antidiabetic activity testing was carried out on
 white rats induced by alloxan treatment. Based on phytochemical screening tests of rice leaf extract,
 components obtained are alkaloid co
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Hendijani, Fatemeh, and Fatemeh Sadat Hosseini. "Interindividual variability in diabetic patients’ response to opium poppy: an overview of impressive factors." Personalized Medicine 19, no. 2 (2022): 155–63. http://dx.doi.org/10.2217/pme-2021-0107.

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Diabetic patients always seek alternative treatments to lower their blood glucose level efficiently, because antidiabetic drugs produce adverse effects and many patients experience reduced response after a treatment period. Opium poppy ( Papaver somniferum) is frequently consumed by diabetic patients for reduction of blood glucose level. Scientific studies found controversial results in the investigation of the blood glucose-lowering effects of opium poppy. In this regard, we explored the antidiabetic effect of opium poppy more closely. The antidiabetic or antihyperglycemic effect of P. somnif
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