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Dissertations / Theses on the topic 'Antifungal and antibacterial activity'

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1

Mohammadihashemi, Marjan. "Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/7411.

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The continuous emergence of drug-resistance pathogens is a global concern. As a result, substantial effort is being expended to develop new therapeutics and mechanisms for controlling microbial growth to avoid entering a "post-antibiotic" era in which commonly used antibiotics are no longer effective in treating infections. In this work, we investigate the efficacy and application of ceragenins as non-peptide mimics of antimicrobial peptides (AMPs). First, this work examines the susceptibility of drug-resistant Gram-negative bacteria. The susceptibility of colistin-resistant clinical isolates
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Mogashoa, Motanti Mary. "Isolation and characterisation of antifungal and antibacterial compounds from Combretum molle (Combretaceae) leaf extracts." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/60270.

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The main aim of this study was to isolate and characterise antifungal and antibacterial compounds from leaf extracts of Combretum molle which belonging to the Combretaceae family. C. molle is one of the commonly used medicinal plants in southern Africa for numerous ailments. Three animal fungal pathogens, namely, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and five plant fungal pathogens, namely, Aspergillus niger, Aspergillus parasiticus, Fusarium oxysporum, Penicillium janthinellum, Rhizoctonia solani and four nosocomial bacteria Staphylococcus aureus, Enterococcus faec
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Alasmary, Fatmah A. S. "Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents. An investigation into the synthesis of substituted benzimidazoles and their evaluation in vitro for antimicrobial activity." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6325.

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Microbe resistence is a serious issue, especially as they have become resistant to most well known drugs. Therefore this is considered as a global problem and is now dealt with at a poitical level. Since no new classes of antimicrobial agents have been discovered in the past three deacdes, the development of new drugs is extremely urgent. Therefore the aim of this project was to synthesise derivatives of benzimidazole, and then assesses their antimicrobial activities in vitro by using disc (well) diffusion and MICs tests. A total of 69 benzimidazole derivatives, with substituents at pos
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4

Alasmary, Fatmah Ali Saeed. "Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents : an investigation into the synthesis of substituted benzimidazoles and their evaluation in vitro for antimicrobial activity." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6325.

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Microbe resistence is a serious issue, especially as they have become resistant to most well known drugs. Therefore this is considered as a global problem and is now dealt with at a poitical level. Since no new classes of antimicrobial agents have been discovered in the past three deacdes, the development of new drugs is extremely urgent. Therefore the aim of this project was to synthesise derivatives of benzimidazole, and then assesses their antimicrobial activities in vitro by using disc (well) diffusion and MICs tests. A total of 69 benzimidazole derivatives, with substituents at positions
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5

Ževžikovienė, Augusta. "Naujų 4-tiazolidinonų, turinčių sulfanilamido, alilamino ir nitrofurano farmakoforus, priešmikrobinių savybių tyrimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120918_161940-39143.

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Klinikinėje praktikoje infekcinėms ligoms gydyti vartojama daugiau kaip 200 priešmikrobinių medžiagų, tačiau infekcinės ligos yra viena dažniausių mirties priežasčių ir naujų priešmikrobinių vaistų poreikis nemažėja. Modifikuojant 4-tiazolidinono žiedą susintetinami įvairaus biologinio aktyvumo junginiai. 4-tiazolidinono dariniai su sulfanilamido farmakoforu yra aktyvesni už sulfanilamidus prieš bakterijas ir pasižymi priešgrybeliniu poveikiu; su nitrofurano farmakoforu yra vieni aktyviausių priešmikrobinių junginių. Alilaminą įjungus į molekulę kartu su jau anksčiau žinomais farmakoforais, ti
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6

Peter, Cristina Mendes. "Atividade antimicrobiana de extratos hidroalcoólicos de própolis marrom, verde e de abelhas jataí (Tetragonisca angustula) frente a micro-organismos infecciosos de interesse em Medicina Veterinária e Humana." Universidade Federal de Pelotas, 2015. http://repositorio.ufpel.edu.br:8080/handle/prefix/3379.

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Submitted by Ubirajara Cruz (ubirajara.cruz@gmail.com) on 2017-05-08T14:44:48Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_Cristina_Peter.pdf: 1012287 bytes, checksum: a6b5ae3184db955c29ee2d8a7adfa70f (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-05-08T14:56:02Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_Cristina_Peter.pdf: 1012287 bytes, checksum: a6b5ae3184db955c29ee2d8a7adfa70f (MD5)<br>Made available in DSpace on 2017-0
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Camargo, Marlene Rodrigues Marcelino. "Avaliação da atividade antimalárica e antimicrobiana de geissosperum argenteum Woodson e Minguartia guianensis Aubl coletadas em Roraima." Universidade Federal de Roraima, 2011. http://www.bdtd.ufrr.br/tde_busca/arquivo.php?codArquivo=130.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Dentre as espécies florestais nativas da Amazônia utilizadas por populações tradicionais na terapêutica de diversos problemas de saúde estão a Geissospermum argenteum Woodson, uma Apocynaceae, e a Minquartia guianensis Aubl., da família Olacaceae. Entre os problemas de saúde está a malária, que no Brasil e no mundo ainda é um grave problema de saúde pública. Outro agravo à saúde de importância são infecções microbianas, pois os micro-organismos têm desenvolvido resistência aos agentes antimicrobianos. Neste trabalho, foram coletada
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Cunha, Let?cia Figueiredo. "Plantas do cerrado brasileiro: triagem fitoqu?mica e de atividades biol?gicas de esp?cies nativas do munic?pio de Diamantina, regi?o do Vale do Jequitinhonha, Minas Gerais." UFVJM, 2016. http://acervo.ufvjm.edu.br/jspui/handle/1/1433.

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?rea de concentra??o: Ci?ncias farmac?uticas.<br>Data de aprova??o ausente.<br>Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2017-08-01T18:51:24Z No. of bitstreams: 2 leticia_figueiredo_cunha.pdf: 6440587 bytes, checksum: 74ac0e7008e3cbee954ff6c0815803c4 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2017-08-14T16:34:13Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) leticia_figueiredo_cunha.pdf: 64405
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Yagi, Sakina. "Etudes phytochimique et biologique de plantes soudanaises : Hydnora johannis Beccari (Hydnoraceae) et Citrullus lanatus (Thunb.) Matsum. et Nakai var. citroides (Bailey) Mansf. (Cucurbitaceae)." Thesis, Nancy 1, 2011. http://www.theses.fr/2011NAN10138.

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Différents extraits ont été préparés à partir de racines de H. johannis et différents tests biologiques ont été appliqués en vue de rechercher différentes activités. L'extrait aqueux s'est montré particulièrement actif sur Enterococcus fecalis, Staphylococcus aureus et Bacillus. Les extraits aqueux dépourvus de tanins et les tanins isolés ne présentent pas d'activité antibactérienne. L'effet synergétique des composés serait donc responsable de l'activité antibactérienne de la plante. Une activité antifongique sur Microsporum canis, une propriété antiradicalaire et une activité antiglycation on
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10

Costa, Helen Paula Silva da. "PurificaÃÃo e caracterizaÃÃo de um inibidor de tripsina com atividade antimicrobiana da torta de pinhÃo-manso (Jatropha curcas L.)." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7773.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>O resÃduo (torta) obtido apÃs a extraÃÃo de Ãleo das sementes de pinhÃo-manso (Jatropha curcas) para a produÃÃo de biodiesel à tÃxico. Apesar dos entraves relacionados à sua utilizaÃÃo na alimentaÃÃo animal, existem evidÃncias de que esse resÃduo tem grande potencial de utilizaÃÃo biotecnolÃgica graÃas ao arsenal de molÃculas que o constitui. Assim, o presente trabalho teve como foco a purificaÃÃo e caracterizaÃÃo de um inibidor de tripsina da torta de pinhÃo-manso, v
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11

Mathekga, Abbey Danny Matome. "Antimicrobial activity of Helichrysum species and the isolation of a new phloroglucinol from Helichrysum caespititium." Diss., Pretoria : [s.n.], 2001. http://upetd.up.ac.za/thesis/available/etd-04012003-141811.

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12

Ribeiro, Martins Xavier Nuno Manuel. "Synthesis of new sugar derivatives containing an α,β -unsaturated carbonyl system in their structure and biological evaluation". Thesis, Lyon, INSA, 2011. http://www.theses.fr/2011ISAL0023.

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Ce travail de doctorat porte sur la synthèse et utilisation de bicyclolactones glycidiques, de façon à accéder des dérivés de sucres contenant un système carbonylé α,β-insaturé. Trois types de bicyclolactones ont été étudiés: butenolides liés à des cycles furanose, butenolides fusionnés à des cycles pyranose, comprenant S- et NH-analogues et carboxyméthyle glycosides lactones (CMGLs). La méthodologie de synthèse de butenolides sur motif sucre est basée sur l’oléfination de Wittig de 3 ou 5-cétosucres et lactonisation intramoléculaire spontanée de gamma-hydroxyesters α,β-insaturés intermédiaire
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13

ANGRI, MATTEO. "FOOD SAFETY AND QUALITY IN DEVELOPING COUNTRIES: THE ROLE OF LACTIC ACID BACTERIA." Doctoral thesis, Università Cattolica del Sacro Cuore, 2016. http://hdl.handle.net/10280/10797.

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La sicurezza e la qualità degli alimenti sono tutt’ora un problema critico per i paesi in via di sviluppo. Le diete a basso contenuto di acido folico, per esempio, possono causare gravi problemi di salute, soprattutto nei bambini. Gravi disturbi legati al tubo neurale (DTN) nei neonati possono derivare infatti da madri che hanno insufficiente apporto di acido folico (400-600 g / giorno) durante il periodo di gravidanza. Inoltre, se non adeguatamente protetti o trattati, I prodotti alimentari possono essere vettori di funghi e batteri patogeni rappresentando una fonte potenziale di malattie per
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ANGRI, MATTEO. "FOOD SAFETY AND QUALITY IN DEVELOPING COUNTRIES: THE ROLE OF LACTIC ACID BACTERIA." Doctoral thesis, Università Cattolica del Sacro Cuore, 2016. http://hdl.handle.net/10280/10797.

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La sicurezza e la qualità degli alimenti sono tutt’ora un problema critico per i paesi in via di sviluppo. Le diete a basso contenuto di acido folico, per esempio, possono causare gravi problemi di salute, soprattutto nei bambini. Gravi disturbi legati al tubo neurale (DTN) nei neonati possono derivare infatti da madri che hanno insufficiente apporto di acido folico (400-600 g / giorno) durante il periodo di gravidanza. Inoltre, se non adeguatamente protetti o trattati, I prodotti alimentari possono essere vettori di funghi e batteri patogeni rappresentando una fonte potenziale di malattie per
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15

Oliveira, Karen Kelly Carvalho de. "Atividade antimicrobiana de basidiomicetos ocorrentes na Amazônia." Universidade Federal do Amazonas, 2014. http://tede.ufam.edu.br/handle/tede/4285.

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Submitted by Alisson Mota (alisson.davidbeckam@gmail.com) on 2015-07-07T18:57:29Z No. of bitstreams: 1 Dissertação - Karen Kelly Carvalho de Oliveira.pdf: 2064619 bytes, checksum: 99e96187d8cd6db44d7bb15b47d1bbe8 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2015-07-07T19:07:54Z (GMT) No. of bitstreams: 1 Dissertação - Karen Kelly Carvalho de Oliveira.pdf: 2064619 bytes, checksum: 99e96187d8cd6db44d7bb15b47d1bbe8 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2015-
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Martins, Táric Ramon Marques. "Síntese, caracterização e avaliação da atividade biológica de ligantes orgânicos da classe das tiossemicarbazonas, semicarbazonas e hidrazonas." Universidade Federal de Goiás, 2017. http://repositorio.bc.ufg.br/tede/handle/tede/7762.

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Submitted by Franciele Moreira (francielemoreyra@gmail.com) on 2017-09-12T17:30:52Z No. of bitstreams: 2 Dissertação - Táric Ramon Marques Martins - 2017.pdf: 2380133 bytes, checksum: 33d24de03c73f9a88934ebdeafa14222 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-09-19T13:43:32Z (GMT) No. of bitstreams: 2 Dissertação - Táric Ramon Marques Martins - 2017.pdf: 2380133 bytes, checksum: 33d24de03c73f9a88934ebdeafa14222 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998e
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Joaquim, Angélica Rocha. "Síntese de derivados de 8-hidroxiquinolina e avaliação da atividade antimicrobiana." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/181465.

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A prospecção e síntese de novos derivados de 8-hidroxiquinolina está em ascensão devido às suas diversas atividades biológicas. Neste trabalho é relatada a síntese e avaliação da atividade antimicrobiana de novos derivados contendo uma sulfonamida substituída na posição 5 da 8-hidroxiquinolina ou um grupamento aminossubstituído na posição 7 da 5-cloro-8-hidroxiquinolina ou 5-cloro-8-metoxiquinolina. Os derivados 5-sulfonamidas foram preparados por clorossulfonação seguida da reação com a amina apropriada. Os derivados 7-aminossubstituído foram sintetizados através da metilação da hidroxila da
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CUNHA, Marcelo Holanda da. "Composição química e atividade biológica do extrato hidroalcoolico de própolis preta." Universidade Federal de Campina Grande, 2018. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/880.

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Submitted by Deyse Queiroz (deysequeirozz@hotmail.com) on 2018-06-05T13:11:17Z No. of bitstreams: 1 MARCELO HOLANDA DA CUNHA - DISSERTAÇÃO PPGSA PROFISSIONAL 2018..pdf: 1249369 bytes, checksum: 6fd10dae8346a148f59677b96d3a3f5a (MD5)<br>Made available in DSpace on 2018-06-05T13:11:17Z (GMT). No. of bitstreams: 1 MARCELO HOLANDA DA CUNHA - DISSERTAÇÃO PPGSA PROFISSIONAL 2018..pdf: 1249369 bytes, checksum: 6fd10dae8346a148f59677b96d3a3f5a (MD5) Previous issue date: 2018-03-05<br>Neste trabalho buscou-se investigar a composição química, o efeito antifúngico e antibacteriano do extrato da própoli
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Nate, Zondi. "Green synthesis of copper and silver nanoparticles and their antimicrobial activity." Thesis, Vaal University of Technology, 2018. http://hdl.handle.net/10352/424.

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M. Tech. (Department of Chemistry, Faculty of Applied and Computer Sciences), Vaal University of Technology<br>The present study includes the use of a green synthetic method to prepare copper and silver nanoparticles using chitosan, aqueous extracts of Camellia sinensis, Combretum molle and Melia azedarach linn leaves. This study aims to investigate the influence of capping and precursor concentration on the properties of silver nanoparticles with emphasis on the medicinal plants chosen. The effect of capping agent on the properties of copper nanoparticles is also investigated. The phytochemic
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Costa, Helen Paula Silva da. "Purificação e caracterização de um inibidor de tripsina com atividade antimicrobiana da torta de pinhão-manso (Jatropha curcas L.)." reponame:Repositório Institucional da UFC, 2012. http://www.repositorio.ufc.br/handle/riufc/16947.

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COSTA, Helen Paula Silva da. Purificação e caracterização de um inibidor de tripsina com atividade antimicrobiana da torta de pinhão-manso (Jatropha curcas L.). 118 f. : Dissertação (Mestrado) - Universidade Federal do Ceará, Centro de Ciências, Departamento de Bioquímica e Biologia Molecular, Programa de Pós-Graduação em Bioquímica. Fortaleza-CE, 2012.<br>Submitted by Eric Santiago (erichhcl@gmail.com) on 2016-05-20T13:42:27Z No. of bitstreams: 1 2012_dis_hpscosta.pdf: 3018720 bytes, checksum: eb4b6b465befb3e7211b53415f21b787 (MD5)<br>Approved for entry into archive by demia Maia (demiamlm@gm
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Pham, Giang Nam. "Développement de nouveaux antibiotiques dirigés contre des bactéries multirésistantes à partir de microorganismes marins inexploités." Electronic Thesis or Diss., Université Côte d'Azur, 2024. http://www.theses.fr/2024COAZ5028.

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La vaste diversité biologique et chimique dans l'environnement marin en fait une ressource précieuse pour la découverte de nouveaux antibiotiques, en réponse à l'émergence de la crise des antibiotiques à l'échelle mondiale. Cependant, le taux de découverte de nouveaux médicaments d'origine marine semble insuffisant par rapport à son potentiel. Dans un effort pour contribuer à la recherche de composés prometteurs pour le développement de nouveaux antibiotiques, nous avons étudié les métabolites secondaires et l'activité biologique de quatre souches de champignons : Fusarium equiseti, Anthracocy
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Dascalu, Anca-Elena. "Bioantibio, biosourced antibacterial and antifungal molecules." Thesis, Lille, 2019. http://www.theses.fr/2019LILUS052.

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Le manque d'innovations thérapeutiques a récemment atteint un niveau critique par rapport aux traitements antibiotiques. Cette question, corrélée à l’apparition de bactéries multirésistantes, a mis en évidence la nécessité de nouvelles approches pour la découverte d’antibiotiques innovants. En conséquence, le projet BIOANTIBIO a été proposé.Les deux principales applications initialement envisagées pour les composés les plus actifs sont:• Additifs pour la formulation de matériaux innovants (par exemple, peintures et revêtements) afin de garantir leur durabilité en stockage (en collaboration ave
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Franche, Antoine. "Amphiphiles azobenzéniques : potentiel et relations structure-activité pour la lyse cellulaire." Thesis, Compiègne, 2019. http://www.theses.fr/2019COMP2523.

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L’émergence de souches bactériennes et fongiques de plus en plus résistantes à la désinfection est un problème qui menace le développement et la santé humaine à travers le monde. Parmi les modes d’action possibles de ces traitements, notre intérêt va se porter sur les interactions avec la membrane plasmique dans le but de lyser le micro-organisme. Le premier objectif de cette thèse est donc de développer des molécules avec une structure amphiphile afin d’interagir avec ces membranes. Les azobenzènes sont intéressants à ce titre car leurs deux groupements phényles constituent déjà un squelette
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Dorla, Emmanuelle. "Étude phytochimique et propriétés bioactives de Peperomia borbonensis (Miq.) Piperaceae." Thesis, La Réunion, 2016. http://www.theses.fr/2016LARE0027.

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Les maladies impliquant des micro-organismes représentent un problème majeur de santé publique en raison du fort taux de mortalité provoqué par l'accroissement et l'émergence de souches résistantes. De même, les régions tropicales du Monde et La Réunion doivent faire face depuis plusieurs années à la pression accrue d'arthropodes ravageurs de cultures et vecteurs de maladies. Pour lutter contre ces arthropodes, les pesticides synthétiques aux conséquences désastreuses sur l'Homme et l'environnement sont principalement utilisés. Depuis quelques années, on observe un phénomène grandissant de rés
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Coventry, Emma. "Antibacterial and antifungal properties of neem (Azadirachta indica A. Juss)." Thesis, University of Aberdeen, 1997. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU100079.

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A number of commercial neem pest control products and a laboratory prepared seed water extract were screened for antibacterial activity against bacteria with different Gram staining reactions, morphologies and pathogenicity using the agar diffusion technique. The neem component of the Trifolio-M GmbH commercial products, termed "active ingredient", and the unformulated product, MIDECOL-CF, exhibited antibacterial activity against Gram-positive and -negative bacteria including phytopathogens. The formulations of the Trifolio-M GmbH products were themselves shown to possess considerable antimicr
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Magnusson, Jesper. "Antifungal activity of lactic acid bacteria /." Uppsala : Dept. of Microbiology, Swedish Univ. of Agricultural Sciences, 2003. http://epsilon.slu.se/a397.pdf.

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Davey, Ronald William. "The antibacterial activity of propolis." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286314.

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Henriques, Ana. "The antibacterial activity of honey." Thesis, Cardiff Metropolitan University, 2006. http://hdl.handle.net/10369/839.

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Honey is an old remedy recently rediscovered as a possible alternative to modern antibiotics in wound management but its mode of action is not fully understood. The antibacterial activity of honey can be divided into hydrogen peroxide and non-hydrogen peroxide-derived activity. This later type of activity is characteristic of honeys from Australasia (e.g. manuka honey) and preferred for wound management, although historically local honeys have been used. The main aim of this study was to investigate the mechanisms of antibacterial action of manuka honey. The stability of antibacterial action o
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Musso, L. "Analogues of natural products with antifungal activity." Doctoral thesis, Università degli Studi di Milano, 2007. http://hdl.handle.net/2434/49159.

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Dorman, Hugh Jude Damien. "Phytochemistry and bioactive properties of plant volatile oils : antibacterial, antifungal and antioxidant activities." Thesis, University of Strathclyde, 1999. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21318.

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Aromatic and medicinal plants have been recognized since antiquity as possessing biological activities; chief amongst these are their antibacterial, antifungal and antioxidant properties. In this study, the chemical composition, the antimicrobial and in vitro antioxidant bioactivities the volatile oils extracted by hydrodistillation from aromatic and medicinal members of the plant families Geraniaceae: geranium (Pelargonium graveolens L'Herit); Lamiaceae: melissa (Melissa officinalis L.), monarda (Monarda citriodora var. citriodora Cerv. ex Lag.), oregano (Origanum vulgare ssp. hirtum (Link) L
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Hansen, Bruce Richard. "Antifungal activity of some New Zealand fungal isolates." Thesis, University of Canterbury. Plant and Microbial Sciences, 1998. http://hdl.handle.net/10092/6849.

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The secondary metabolism of organisms, especially mycelial fungi, is attracting increasing attention since it may produce a reservoir of unique molecules from which therapeutic agents are formed or derived for clinical application The production of secondary metabolites is not well understood and involves a broad spectrum of metabolic processes that often have little in common. This study screened a number of New Zealand isolates, mostly of the Arthrinium genus, and assessed their antifungal activity. The primary screening used for this study consisted of agar diffusion tests with a range of
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Fewell, Alison. "Interactive antifungal activity between co-occurring Solanum glycoalkaloids." Thesis, University of Exeter, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359158.

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de, Beer Irving. "Screening of plant-mediated nanoparticles for antifungal activity." University of the Western Cape, 2020. http://hdl.handle.net/11394/7955.

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>Magister Scientiae - MSc<br>Nanotechnology is spreading rapidly across the world as an extremely powerful technology. Nanoscience and nanotechnology are innovative scientific advancements that have been introduced only in this century. Nanotechnology has developed as the scientific advancement to grow and transform the entire agri-food area, with the potential to elevate global food production, in addition to the nutritional value, quality, and safety of food and food products. It has gained recognition due to its variability in shape, size, and dimension and how it correlates to its possibil
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Palamar, A. O. "Antimicrobial and antifungal activity of certain imidazole compounds." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18908.

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Al-Sagher, Mohamed Ramadan. "Antibacterial activity of galactoside analogues of biocides." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315112.

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Pereira, Joana Brás. "Synthesis and antibacterial activity of cationic phthalocyanines." Master's thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/8999.

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Mestrado em Biologia Molecular e Celular<br>Antimicrobial photodynamic therapy (aPDT) was described more than 100 years ago, but its potential as an alternative to combating microorganisms, was only recognized when antibiotic resistance became an important public health issue. aPDT refers to the action of 3 non-toxic elements: a photosensitizer, light and molecular oxygen that, when combined, results in the production of singlet oxygen (1O2) and/or free radicals which are cytotoxic to target cells. The aim of this work was to synthetize, evaluate and compare the photoinactivation effici
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Ta, Chieu Anh Kim. "Bacterial Biofilm Inhibition and Antifungal Activity of Neotropical Plants." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32419.

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This thesis examined the antimicrobial activity of select neotropical plants from Costa Rica and traditional Q’eqchi Maya medicines from Belize. In particular the potential for interference with bacterial quorum sensing (QS) and biofilm formation as well as fungal growth were assessed. Of one hundred and twenty six extracts collected from Costa Rica, one third showed significant QS inhibition while 13 species displayed more biofilm inhibitory activities than the positive control allicin. The active species belonged to the Lepidobotryaceae, Melastomataceae, Meliaceae, Sapindaceae, and Simarouba
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Tshanga, Siphokazi Sisanda. "Antibacterial activity of liposome encapsulated cyclo(TYR-PRO)." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/1450.

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Cyclic dipeptides (CDPs) are amino acid-based compounds, some of which possess antibacterial activity. The encapsulation of certain drugs into liposomes has been found to improve their activity in terms of bioavailability and duration of action. Liposomes are small vesicles that are under investigation as drug carriers for the delivery of therapeutic agents. A number of liposome formulations are currently under clinical trial review, whilst some have already been approved for clinical use. The aim of this study was to optimize a liposomal cyclo(Tyr-Pro) formulation and to assess its antibacter
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Barber, Megan Marie. "2,4-Disubstituted Quinazolines with Antileishmanial or Antibacterial Activity." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5840.

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Herein 47 2,4-disubstituted quinazolines were synthesized and tested against Leishmania donovani intracellular amastigotes. A structure-activity relationship was conducted and lead to the identification of quinazolines with EC50s in the single digit and high nanomolar range with favorable antileishmanial selectivity indexes. Quinazoline 2.6 and 2.31 underwent in vivo efficacy studies in murine models of visceral leishmaniasis, reducing liver parasitemia by 12 % and 24 %, respectively, when given by the intraperitoneal route at 15 mg/kg/day x 5 days. The antileishmanial efficacy and easy of syn
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Albaridi, Najla. "The antibacterial activity of honey against Campylobacter jejuni." Thesis, University of Surrey, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616479.

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Honey is a food with high popularity, consumption and availability. The effective antibacterial activity of honey, without any reported bacterial resistance or side effects, increases its use in traditional medicine for treating many different kinds of infections. Initially, this study examined the antibacterial activity of honey against Campylobacter jejuni. Six different types of honey, which were commercially available in the UK, Saudi Arabia and New Zealand, were assessed. Honey samples were introduced to Muller Hinton media in three different ways: filtration, autoclaving honey alone and
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Cushnie, T. P. Tim. "Investigation of the antibacterial activity of selected flavonoids." Thesis, Robert Gordon University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430050.

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Elfakhri, S. O. "Antibacterial activity of novel self-disinfecting surface coatings." Thesis, University of Salford, 2014. http://usir.salford.ac.uk/33219/.

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The antibacterial activities of different thin films (TiO2/CuO, Cu/SiO2 and Ag/SiO2) prepared by flame-assisted chemical vapour deposition (FACVD) and atmospheric pressure thermal (APT-FCVD) for TiO2/CuO films, were investigated against standard strains of bacteria used for disinfectant testing and against multi-antibiotic resistant bacteria that have been shown to persist in the hospital environment. These included; MRSA strains (EMRSA15 and two recent clinical isolates MRSA 1595 and MRSA 1669), extended spectrum β-lactamase (ESBL) producing Escherichia coli, a second (ESBL- 2 ) producing Esch
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Cherrington, Christina Anne. "The antibacterial activity of short-chain organic acids." Thesis, University of Bristol, 1989. http://hdl.handle.net/1983/77ce9cef-1fa2-4387-8b84-f26df3f53717.

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Almeida, Beatriz Luciana Tavares de. "Investigating the antibacterial activity of Pedobacter lusitanus NL19." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/21523.

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Blaxland, James. "The antibacterial activity of Humulus lupulus against mycobacteria." Thesis, Cardiff University, 2015. http://orca.cf.ac.uk/73639/.

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One third of the world’s population is estimated to be infected with M. tuberculosis, a pathogen which causes more human death and misery than any other bacterial disease. Whilst treatment is available, resistance to commonly used antimicrobials is a growing problem. Thus there is an urgent need to identify new compounds that can kill drug resistant isolates and are able to potentiate the activity of currently available antibiotics. The plant kingdom is a rich source of antibacterial compounds and a plant which has attracted particular interest is Humulus lupulus, more commonly known as the ho
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Yang, Mandy. "An investigation of the antifungal and antitumor activity of ajoene." Thesis, University of Canterbury. Biological sciences, 2013. http://hdl.handle.net/10092/8201.

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The garlic extract ajoene is considered to have antimicrobial and antitumor effects against a variety of cell types, and it is suggested to have the potential to be used as an antifungal or antitumor drug clinically. The underlying mechanism of its inhibitory effects is still uncertain. In this project, the effects of ajoene on the growth of fungal and oomycete cells were studied on Candida albicans, Neurospora crassa and Achlya bisexualis. Endometrial cancer is the most common gynecologic cancer. A 3D spheroid model of endometrial cancer cells were for the first time used to i
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Thomas, Russell John. "The synthesis of novel #beta#-lactams with potential antifungal activity." Thesis, University of Exeter, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277147.

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Asmyou, Sana Alhadi. "An in-vitro study of antifungal activity of gymnemic acid." University of the Western Cape, 2017. http://hdl.handle.net/11394/6239.

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Magister Chirurgiae Dentium - MChD (Oral Medicine and Periodontics)<br>Candida species are frequently isolated from oral mucosal surfaces of healthy individuals and is the most common genus responsible for up to 75% of all candidal infections. The most common problems associated management of oral candidiasis are antifungal drug resistance and side effects Natural medicine is an emerging field and is being explored to overcome drug resistance and to reduce side effects. Gymnemagenin (will be known as Gymnemic acid; GA) is a purified extract from Gymnema sylvestre, a slow growing, perennia
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Silva, Maria Zelandia Rocha. "Insulation immunoaffinity chromatography and antifungal activity osmotinas of latex fluid." Universidade Federal do CearÃ, 2015. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=14503.

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CoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior<br>Plants are constantly exposed to a variety of stresses conditions. However, they react to biotic stresses by triggering a set of defense mechanisms including the synthesis of defensive substances as the pathogenesis-related (PR) proteins. The PR-protein named osmotin can be induced under osmotic stress and water shortage conditions. Osmotin-like proteins have been purified from latex and some of them are related to antifungal activity. The aim of this study was to investigate the osmotin in the following species laticifers: C. grand
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Clarke, Annette June Morgan. "The physical characterization and antibacterial activity of herring protamines." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0029/MQ47419.pdf.

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