Academic literature on the topic 'Antifungal drus'

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Journal articles on the topic "Antifungal drus"

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Meletiadis, Joseph, Saigh Rafal Al, Aristea Velegraki, Thomas Walsh, Emmanuel Roilides, and Loukia Zerva. "Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model." Antimicrobial agents and chemotherapy 56, no. 11 (2011): 403–10. https://doi.org/10.1128/AAC.00662-11.

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In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations. Therefore, we developed a new in vitro pharmacokinetic/pharmacodynamic model where human plasma pharmacokinetics of standard doses of 1 mg/kg amphotericin B, 4 mg/kg voriconazole, and 1 mg/kg caspofungin were simulated and their pharmacodynamic characteristics were determined against three clinical isolates of Aspergillus fumigatus, Aspergillus flavus, and Aspergillus terreus with identical MICs (1 mg/liter for amphotericin B, 0.5 mg/liter for vorico
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Begum, Jubeda, and P. Das. "Antifungal resistance in dermatophytosis: A global health concern." Letters In Animal Biology 2, no. 1 (2022): 41–45. http://dx.doi.org/10.62310/liab.v2i1.76.

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Dermatophytosis is a common dermatological problem in animals as well as humans which is associated with interference in immune function. Unlike the antibacterial resistance which is frequently reported, antifungal resistance is less commonly reported, but there are reports of emerging antifungal resistance in humans and animals. The problem of antifungal resistance can be more severe in comparison to any other drug resistance due to the limited number of antifungals available for therapeutic purpose. A number of mechanisms have been put forward to explain the phenomenon of antifungal drug res
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Mandal, Debashree. "Evaluating the Impact of Antifungal Drugs on Human Health and Exploring Alternative Treatments." Oriental Journal Of Chemistry 40, no. 3 (2024): 630–45. http://dx.doi.org/10.13005/ojc/400302.

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Fungi occurred naturally like Candida yeast, in the human body. It may grow on skin, inside the digestive system and vagina. Antifungal drugs are used to kill or stop this fungal growth. According to their mode of action they are divided into azoles (inhibit ergosterol synthesis), echinocandins (damage cell walls), and polyenes (destroy fungal cells) etc. Depending on the seriousness of infection and type of infection, generally antifungal drugs are administered to a body. Oral antifungals are taken by mouth for systemic infections. Topical antifungals (creams, ointments) treat localized skin
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Jha, Anubhuti, and Awanish Kumar. "Anticandidal agent for multiple targets: the next paradigm in the discovery of proficient therapeutics/overcoming drug resistance." Future Medicinal Chemistry 11, no. 22 (2019): 2955–74. http://dx.doi.org/10.4155/fmc-2018-0479.

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Candida albicans is a prominent human fungal pathogen. Current treatments are suffering a massive gap due to emerging resistance against available antifungals. Therefore, there is an ardent need for novel antifungal candidates that essentially have more than one target, as most antifungal repertoires are single-target drugs. Exploration of multiple-drug targeting in antifungal therapeutics is still pending. An extensive literature survey was performed to categorize and comprehend relevant studies and the current therapeutic scenario that led researchers to preferentially consider multitarget d
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Arastehfar, Amir, Toni Gabaldón, Rocio Garcia-Rubio, et al. "Drug-Resistant Fungi: An Emerging Challenge Threatening Our Limited Antifungal Armamentarium." Antibiotics 9, no. 12 (2020): 877. http://dx.doi.org/10.3390/antibiotics9120877.

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The high clinical mortality and economic burden posed by invasive fungal infections (IFIs), along with significant agricultural crop loss caused by various fungal species, has resulted in the widespread use of antifungal agents. Selective drug pressure, fungal attributes, and host- and drug-related factors have counteracted the efficacy of the limited systemic antifungal drugs and changed the epidemiological landscape of IFIs. Species belonging to Candida, Aspergillus, Cryptococcus, and Pneumocystis are among the fungal pathogens showing notable rates of antifungal resistance. Drug-resistant f
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Soe, Hay Man Saung Hnin, Phyo Darli Maw, Thorsteinn Loftsson, and Phatsawee Jansook. "A Current Overview of Cyclodextrin-Based Nanocarriers for Enhanced Antifungal Delivery." Pharmaceuticals 15, no. 12 (2022): 1447. http://dx.doi.org/10.3390/ph15121447.

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Fungal infections are an extremely serious health problem, particularly in patients with compromised immune systems. Most antifungal agents have low aqueous solubility, which may hamper their bioavailability. Their complexation with cyclodextrins (CDs) could increase the solubility of antifungals, facilitating their antifungal efficacy. Nanoparticulate systems are promising carriers for antifungal delivery due to their ability to overcome the drawbacks of conventional dosage forms. CD-based nanocarriers could form beneficial combinations of CDs and nanoparticulate platforms. These systems have
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Gunawan, Untung, Slamet Ibrahim, Atthar Luqman Ivansyah, and Sophi Damayanti. "Separation and analysis of triazole antifungal in biological matrices by liquid chromatography: a review." Pharmacia 70, no. 4 (2023): 1265–81. http://dx.doi.org/10.3897/pharmacia.70.e111511.

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Invasive fungal infections cause serious illness and death worldwide. Long-term therapeutic and preventative use of antifungal drugs in high-risk patients has caused resistance. Triazole antifungals are widely used to prevent and treat fungal infections, and therapeutic drug monitoring has been suggested to improve outcomes, reduce toxicity, and prevent drug resistance. Common methods used for monitoring triazole antifungal drugs in biological matrices such as blood, serum, and plasma include bioassay and instrumentation methods, especially liquid chromatography. Sample preparation is needed t
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Gunawan, Untung, Slamet Ibrahim, Atthar Luqman Ivansyah, and Sophi Damayanti. "Separation and analysis of triazole antifungal in biological matrices by liquid chromatography: a review." Pharmacia 70, no. (4) (2023): 1265–81. https://doi.org/10.3897/pharmacia.70.e111511.

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Invasive fungal infections cause serious illness and death worldwide. Long-term therapeutic and preventative use of antifungal drugs in high-risk patients has caused resistance. Triazole antifungals are widely used to prevent and treat fungal infections, and therapeutic drug monitoring has been suggested to improve outcomes, reduce toxicity, and prevent drug resistance. Common methods used for monitoring triazole antifungal drugs in biological matrices such as blood, serum, and plasma include bioassay and instrumentation methods, especially liquid chromatography. Sample preparation is needed t
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Cai, Tian, Youming Liao, Zhenhua Chen, Yingchang Zhu, and Xincai Qiu. "The Influence of Different Triazole Antifungal Agents on the Pharmacokinetics of Cyclophosphamide." Annals of Pharmacotherapy 54, no. 7 (2020): 676–83. http://dx.doi.org/10.1177/1060028019896894.

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Background: Cyclophosphamide is one of the most important chemotherapeutic drugs. Known as a widely accepted treatment strategy, chemotherapy may damage the immune function of cancer patients; as a result, invasive fungal infections (IFIs) occur. Triazole antifungal agents are the most acceptable drugs for IFI treatment, especially those infections caused by chemotherapy. Objective: We aimed to investigate the effects of different triazole antifungal drugs, including fluconazole, itraconazole, and ketoconazole, on the pharmacokinetics (PK) of cyclophosphamide. In addition, we also characterize
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Sharma, Jehoshua, Sierra Rosiana, Iqra Razzaq, and Rebecca Shapiro. "Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens." Journal of Fungi 5, no. 1 (2019): 17. http://dx.doi.org/10.3390/jof5010017.

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Fungal infections are a growing public health concern, and an increasingly important cause of human mortality, with Candida species being amongst the most frequently encountered of these opportunistic fungal pathogens. Several Candida species are polymorphic, and able to transition between distinct morphological states, including yeast, hyphal, and pseudohyphal forms. While not all Candida pathogens are polymorphic, the ability to undergo morphogenesis is linked with the virulence of many of these pathogens. There are also many connections between Candida morphogenesis and antifungal drug trea
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Dissertations / Theses on the topic "Antifungal drus"

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Lai, Yu-Wen. "Transcriptomic analysis of synergy between antifungal drugs and iron chelators for alternative antifungal therapies." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/17064.

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There is an urgent need to improve the efficacy and range of antifungal drugs due to a global increase in invasive fungal infections, which are difficult to treat and are associated with high rates of mortality. Developing new drugs is expensive and time consuming and synergistic therapies that enhance the efficacy of current drugs are an alternative approach. Iron chelators have been used as antifungal synergents in salvage therapy, however, how these cause synergy are unknown. This thesis aims to use a transcriptomic approach to understand the mechanistic detail of antifungal-chelator synerg
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Sabzevari, Omid. "Azole antifungal drugs and cytochrome P450 induction." Thesis, University of Surrey, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359878.

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Venkateswarlu, Kanamarlapudi. "Azole antifungal drugs mode of action and resistance." Thesis, University of Sheffield, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389558.

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Barbosa, Mónica Rodrigues. "Evolution of antifungal drug resistance in Candida albicans." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/15332.

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Mestrado em Biologia Molecular e Celular<br>The human pathogen Candida albicans is characterized by the presence of a hybrid tRNA (tRNACAGSer) that can be aminoacylated by both LeuRS and SerRS. This tRNA is responsible for the ambiguity of the CUG codon that can be decoded as serine (97%) and Leucine (3%). Previous studies showed that the level of ambiguity is variable depending on the growth condition of the fungus. These studies also revealed that strains mistranslating at a higher level grew better in the presence of azoles, particularly in the presence of fluconazole. To analyse the effec
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Araújo, Ana Rita Dias. "Antifungal drug resistance driven by mistranslation in yeast." Master's thesis, Universidade de Aveiro, 2011. http://hdl.handle.net/10773/7942.

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Mestrado em Biotecnologia Molecular<br>Antifungal drug resistance has become a severe clinical problem and new targets for the development of new antifungal drugs need to be discovered. Ongoing work in our laboratory indicates that codon mistranslation due to codon ambiguity accelerates antifungal drug resistance in the human pathogen Candida albicans. The present work aimed to elucidate if non pathogenic yeasts behave similarly. Therefore, mistranslation was artificially induced in Saccharomyces cerevisiae strains by the expression of chimeric tRNAs. Each of the constructed strains car
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Dahal, Gopal Prasad. "Development of Selective Inhibitors against Enzymes Involved in the Aspartate Biosynthetic Pathway for Antifungal Drug Development." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1532889045486984.

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Grice, Christopher Martin. "Peptide aptamer selection for antifungal drug discovery and diagnostics." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/51495.

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The demand for more effective fungal diagnostics and therapeutics is becoming increasingly urgent with increases in incidence of fungal diseases, antifungal resistance and lack of rapid diagnosis resulting in high mortality rates. The research described in this thesis evaluates the Aspergillus fumigatus pH-signalling receptor PalH (which non-redundantly regulates processing of the transcription factor PacC, and is essential for pathogenicity), as a viable therapeutic target. To assess intracellular modulation of PalH functionality, a novel proof-of-principle library of peptide aptamers (PAs),
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Vincent, Benjamin Matteson. "Exploiting fitness trade-offs to prevent antifungal drug resistance." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/99573.

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Thesis: Ph. D. in Microbiology, Massachusetts Institute of Technology, Department of Biology, 2015.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references<br>The evolution of drug resistance in pathogenic microorganisms is typically viewed as an inevitable consequence of the selective pressures imposed by antimicrobial agents. However, although certain drugs rapidly lose efficacy in the clinic, others remain refractory to resistance. In my thesis, I tested the hypothesis that antifungal drug resistance is the outcome of diverse tradeoffs between the fitness benefits of
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Böttiger, Ylva. "Metabolic drug interactions in man : methodological aspects on in vivo studies /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4207-2/.

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Wetter, Tracy Jane. "Advances in yeast and mold monodrug and combination drug antifungal susceptibility testing." Diss., Montana State University, 2004. http://etd.lib.montana.edu/etd/2004/wetter/WetterT04.pdf.

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Books on the topic "Antifungal drus"

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St, Georgiev Vassil, New York Academy of Sciences., and International Conference on Drug Research in Immunologic and Infectious Diseases (1st : 1987 : Garden City, N.Y.), eds. Antifungal drugs. New York Academy of Sciences, 1988.

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Krysan, Damian J., and W. Scott Moye-Rowley, eds. Antifungal Drug Resistance. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3155-3.

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Fernandes, Prabhavathi B., ed. New Approaches for Antifungal Drugs. Birkhäuser Boston, 1992. http://dx.doi.org/10.1007/978-1-4899-6729-9.

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B, Fernandes P., ed. New approaches for antifungal drugs. Birkhäuser, 1992.

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Manzoor, Nikhat, ed. Advances in Antifungal Drug Development. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-5165-5.

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1934-, Yamaguchi Hideyo, Kobayashi George S. 1927-, Takahashi Hisashi 1929-, and International Conference on Antifungal Chemotherapy (1st : 1990 : Oiso-machi, Japan), eds. Recent progress in antifungal chemotherapy. Dekker, 1992.

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1923-, Jacobs Paul H., and Nall Lexie 1932-, eds. Antifungal drug therapy: A complete guide for the practitioner. M. Dekker, 1990.

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J, Ernst Erika, and Rogers P. David, eds. Antifungal agents: Methods and protocols. Humana Press, 2005.

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International, Telesymposium on Recent Trends in the Discovery Development and Evaluation of Antifungal Agents (1987). Recent trends in the discovery, development and evaluation of antifungal agents: Proceedings of an international telesymposium, May 1987. J.R. Prous Science, 1987.

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Hall, Gerri S. Interactions of yeasts, moulds, and antifungal agents: How to detect resistance. Humana Press, 2012.

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Book chapters on the topic "Antifungal drus"

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Hay, Roderick J. "Antifungal Drugs." In European Handbook of Dermatological Treatments. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45139-7_132.

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Hay, R. J. "Antifungal drugs." In European Handbook of Dermatological Treatments. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-07131-1_122.

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Bustamante, Beatriz, Jose A. Hidalgo, and Pablo E. Campos. "Antifungal Drugs." In Current Progress in Medical Mycology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64113-3_2.

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Hay, Roderick J. "Antifungal Drugs." In European Handbook of Dermatological Treatments. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-15130-9_135.

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Karmarkar, Neeta, Pooja Shah, and Kalpana Rathod. "Antifungal Drugs." In Principles and Practice of Neurocritical Care. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-8059-8_20.

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Bhandari, Prasan. "Antifungal drugs." In Pharmacology Mind Maps for Medical Students and Allied Health Professionals. CRC Press, 2019. http://dx.doi.org/10.1201/9780429023859-70.

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Raj, Gerard Marshall. "Antifungal Drugs." In Introduction to Basics of Pharmacology and Toxicology. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-6009-9_57.

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Dharmaiah, Sharvari, Rania A. Sherif, and Pranab K. Mukherjee. "Antifungal drug resistance: Significance and mechanisms." In Antifungal Therapy. CRC Press, 2019. http://dx.doi.org/10.1201/9780429402012-4.

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Rhee, Douglas J., Kathryn A. Colby, Lucia Sobrin, and Christopher J. Rapuano. "Antifungal Agentsп." In Ophthalmologic Drug Guide. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7621-5_2.

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Amsden, Jarrett R., and Paul O. Gubbins. "Antifungal Agents." In Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-72416-4_11.

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Conference papers on the topic "Antifungal drus"

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Ali Alzamily, Ihsan, Hassan Ali Tamur, and Murtadha M Hussein. "Evaluation The Efficacy of Ocimum Basilicum Extract & Antifungal Agents Against Some Pathogenic Filamentous Fungi." In IX. International Scientific Congress of Pure, Applied and Technological Sciences. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress9-6.

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: The widespread availability of chemical-based medications opened a way for researchers to look for alternatives, returning to the primary source of drugs. Plants have been utilized for their healing abilities since ancient times since they have been proved to cure diseases. some filamentous fungi used such as Aspergillus, Penicillium, Fusarium, Trichophyton and Cladosporium. The study included use of four types of antifungals agents, Ketoconazole, Fluconazole, Itraconazole and Nystatin, the study conducted that Fluconazole have the highest effect with inhibition zone of (37mm) against Asperg
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Al-Garawi, Noor Al-Houda D., Marwa Ahmed Meri, and R. A. Sahib. "Candida auris: Virulence and antifungal drugs resistance." In 4TH INTERNATIONAL SCIENTIFIC CONFERENCE OF ALKAFEEL UNIVERSITY (ISCKU 2022). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0181986.

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Mali, Ravindra, and Javesh Patil. "Nanoparticles: A Novel Antifungal Drug Delivery System." In IOCN 2023. MDPI, 2023. http://dx.doi.org/10.3390/iocn2023-14513.

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de A. M. Marques, Maria Júlia, Fernanda Alves, Francisco Guimarães, and Cristina Kurachi. "Evaluation of the antimicrobial photodynamic response of Rhizopus oryzae." In Frontiers in Optics. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/fio.2023.jtu5a.3.

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Mucormycosis, a fungal disease, has high mortality despite aggressive treatment. Antimicrobial photodynamic therapy (aPDT), an alternative to antifungal drugs, showed partial inhibition of R. oryzae in vitro growing in all life cycles.
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Kim, Jong H., Kathleen L. Chan, Luisa W. Cheng, et al. "High Efficiency Drug Repurposing for New Antifungal Agents." In 4th International Electronic Conference on Medicinal Chemistry. MDPI, 2018. http://dx.doi.org/10.3390/ecmc-4-05620.

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Abdulkhazhieva, Aiset Shaamanovna. "Use Of Antifungal Drugs And Immunomodulator For Cat Microsporais." In International Conference "Modern trends in governance and sustainable development of socio-economic systems: from regional development to global economic growth". European Publisher, 2024. http://dx.doi.org/10.15405/epms.2024.09.2.

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Rodrigues da Silva, Abdênego, Fernanda Viana Cabral, Adriana Fontes, and Martha Ribeiro Simões. "Light-based antifungal strategy for the control of Candida auris." In Latin America Optics and Photonics Conference. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.w4a.58.

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Candida auris is a pathogen that has been attracting worldwide focus due to its high resistance to conventional drugs. This work evaluated the photodynamic inactivation mediated by two phenothiazine dyes against the CBS 10913 strain.
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Mangalagiu, Violeta, Dumitrela Diaconu, and Ionel Mangalagiu. "Quinoline - sulfonamide - complexes with antimicrobial activity." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab26.

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Quinoline-sulfonamide-complexes with variously metals, especially M2+, are a relatively new class of compounds with potential practical interest as fluorescent materials (having fotoluminiscent properties) and also as drugs (having a large variety of biological activities such as antibacterial, antifungal, antiprotozoals, etc.). The emphasis of this work was to obtain hybrid quinoline – sulfonamide - complexes with antimicrobial activity. The synthesis of the hybrid derivatives is direct and efficient, in two steps: acylation of variously amino-quinoline followed by metal complexation with dif
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Marrero-Ponce, Yovani, Ricardo Marrero, Yunaimy Díaz, et al. "TOMOCOMD-CARDD Method in Early Drug Discoverybased Rational Drug Selection of Antifungal Agents." In The 12th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01274.

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Mangalagiu, Violeta, Dumitrela Diaconu, Costel Moldoveanu, et al. "Hybrid and chimeric nitrogen heterocycles with biological activity." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab01.

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Nitrogen heterocycles, especially azine and azole derivatives, are highly valuable scaffolds in medicinal chemistry, being the core components of a large variety of drugs with variously biological activity such as antiplasmodial and antimalarial, antitubercular, antibacterial, antifungal, anticancer, analgesic, antidepressant, anxiolytics, antihypertensive, anticoagulants, diuretics, etc. As a result, obtaining of such entities continues to arouse a strong interest from academia and industry. As part of our ongoing research in the area of nitrogen heterocyclic derivatives, we present herein so
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Reports on the topic "Antifungal drus"

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He, Dan, Hongmei Wu, Yujie Han, Min Liu, and Mao Lu. A meta-analysis of topical antifungal drugs to treat atopic dermatitis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0062.

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Review question / Objective: Various bacteria and fungi colonize the skin surface of patients with AD. The colonized fungi mainly include Malassezia, non-Malassezia yeasts, and molds. Among them, Malassezia occupies 63%~86% of the fungal colonization community on the skin surface of AD patients. Although the relationship between the level of Malassezia on the skin surface and disease severity remains controversial, many studies have shown that the level of serum anti-Malassezia-specific immunoglobulin E (IgE) antibodies in AD patients is related to the disease severity, especially in patients
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Li, Chang, Lin Sun, Yin Liu, et al. The Efficacy of antifungal drugs combined with hormones in the treatment of allergic bronchopulmonary aspergillosis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.5.0073.

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Song, Yinggai, Paul E. Verweij, Jochem B. Buil, et al. Analysis of susceptibility and drug resistance of antifungal agents in aspergillosis andmucormycosis patients: A Systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.7.0069.

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Wu, Shunyu, Yin Cheng, Shunzhang Lin, and Huanhai Liu. A Comparison of Antifungal Drugs and Traditional Antiseptic Medication for Otomycosis Treatment: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.3.0057.

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Cheng, Jing, Hedong Han, Wenwen Kang, Zijin Cai, Ping Zhan, and Tangfeng Lv. Comparison of Antifungal Drugs in the Treatment of Invasive Pulmonary Aspergillosis: A Systematic Review and Network Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0105.

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Maheshwari, E. Uma, and G. Jyothilakshmi. A STUDY OF ANTIFUNGAL SUSCEPTIBILITY TESTING AMONG NON ALBICANS CANDIDA IN PATIENTS OF VULVO VAGINAL CANDIDIASIS AT TERTIARY CARE CENTER. World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/9605846.

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Background &amp;objectives: Candida species are emerging as a signicant pathogen certain species of Candida like Candida krusei are inherently resistant to azoles. In vitro susceptibility testing is essential for guiding therapy. The present study aims todetermine the antifungal susceptibility pattern ofNon albicansCandida isolates by disc diffusion and micro broth dilution method. Methods:This was a prospective study, conducted among 200 patients complaining of Vulvovaginal dischargeSpeciation was done as per standard microbiological methods. Non albicans Candida species were identied. Anti
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