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Journal articles on the topic 'Antifungal spray'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Sardo, A. "Fruit, vegetables & nuts Antifungal spray." Trends in Food Science & Technology 8, no. 8 (1997): 281. http://dx.doi.org/10.1016/s0924-2244(97)87549-8.

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2

Craig Bettenhausen. "Benzene found in antifungal spray drugs." C&EN Global Enterprise 99, no. 37 (2021): 13. http://dx.doi.org/10.1021/cen-09937-buscon2.

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3

Prof., Kshitij S. Varma*, V. Sonawane Vedant, S. Sonawane Siddhi, et al. "FORMULATION AND EVALUATION OF ANTIFUNGAL SPRAY." World Journal of Pharmaceutical Science and Research 4, no. 1 (2025): 266–80. https://doi.org/10.5281/zenodo.14785837.

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Patil, Tejashree, Madhavi Parab, Shriram Bairagi, and Smita Takarkhede. "A current Research on the Green Synthesis of Copper Nanoparticles from Herbal Extract." Asian Journal of Pharmaceutical Research and Development 11, no. 4 (2023): 46–51. http://dx.doi.org/10.22270/ajprd.v11i4.1289.

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The study aims to find out the effectiveness of the combination of citral and curcumin as antifungal compounds. Lemongrass (Cymbopogon citratus) is a valuable family of grass known due to its flavoring, medicinal, and fragrance application. Haldi (Turmeric) scientifically known as Curcuma longa belongs to familthey Zingiberaceae. Its polyphenolic compound curcumin has been showing a variety of antifungal investigations due to extensive traditional uses and very low side effects.Turmeric has beenutilized in traditional medicine for various diseases counting diabetes, hepatitis, hemorrhoids, hys

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Divya, Shirke, and Shirke Bhushan. "Formulation & Development of Transdermal Spray of Turmeric Lemongrass as Antifungal." Asian Journal of Pharmaceutical Research and Development 11, no. 4 (2023): 12–23. http://dx.doi.org/10.22270/ajprd.v11i4.1279.

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The study aims to find out the effectiveness of the combination of citral and curcumin as antifungal compounds. Lemongrass (Cymbopogon citratus) is a valuable family of grass known due to its flavoring, medicinal, and fragrance application. Haldi (Turmeric) scientifically known as Curcuma longa belongs to familthey Zingiberaceae. Its polyphenolic compound curcumin has been showing a variety of antifungal investigations due to extensive traditional uses and very low side effects.Turmeric has beenutilized in traditional medicine for various diseases counting diabetes, hepatitis, hemorrhoids, hys

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Babu, N. Raghavendra, A. Divya, Y. Padmavathi, T. Vinoda, M. Subha Sree, and A. G. Prasanna Lakshmi. "Development of New Sensitive Spectrophotometric Method for Estimation of Famciclovir Using 3-Amino Phenol." Asian Journal of Pharmaceutical Research and Development 11, no. 4 (2023): 24–29. http://dx.doi.org/10.22270/ajprd.v11i4.1280.

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The study aims to find out the effectiveness of the combination of citral and curcumin as antifungal compounds. Lemongrass (Cymbopogon citratus) is a valuable family of grass known due to its flavoring, medicinal, and fragrance application. Haldi (Turmeric) scientifically known as Curcuma longa belongs to familthey Zingiberaceae. Its polyphenolic compound curcumin has been showing a variety of antifungal investigations due to extensive traditional uses and very low side effects.Turmeric has beenutilized in traditional medicine for various diseases counting diabetes, hepatitis, hemorrhoids, hys

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Mohini Shekhar Dhule, Mohini Shekhar Dhule, Sukanya Vilas Lad Sukanya Vilas Lad, Mr Krishna Khamkar Mr. Krishna Khamkar, and Dr Rajnikant Kakade Dr.Rajnikant Kakade. "A Study on the Preparation and Evaluation of an Herbal Antifungal Spray." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 669–79. https://doi.org/10.35629/4494-1003669679.

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This study presents the formulation and evaluation of herbal antifungal spray developed using natural ingredients like karanja oil, neem oil, black pepper extract, camphor and other ingredient. Now a days the fungal infection is risen in humans. Along with its growth rate, the kind of fungal species also increased considerably. For this situation effective formulation is necessary to treat these fungal infections in a simple manner. The primary objective of my research project was to create a formulation for a herbal antifungal spray. Research into tropical antifungal formulations has demonstr

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Shinare, Snehal* Tambe Sagar. "Formulation and Evaluation of Herbal Antifungal Sprays: A Systematic Review." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4881–86. https://doi.org/10.5281/zenodo.15551037.

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In recent years, it has been found that fungal infections in humans have risen. Along with its growth rate, the kind of fungal species also increased considerably. An effective formulation is necessary to treat these fungal infections in a simple manner. The main aim of my research project was to develop a formulation of a topical antifungal spray. The formulation and development of tropical antifungal formulation have seen great results in the treatment of fungal infections. Over the conventional dosage forms, these topical drug delivery formulations have more benefits along with their extrao

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Shinare, Snehal* Tambe Sagar. "Formulation and Evaluation of Herbal Antifungal Sprays: A Systematic Review." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4881–86. https://doi.org/10.5281/zenodo.15551118.

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In recent years, it has been found that fungal infections in humans have risen. Along with its growth rate, the kind of fungal species also increased considerably. An effective formulation is necessary to treat these fungal infections in a simple manner. The main aim of my research project was to develop a formulation of a topical antifungal spray. The formulation and development of tropical antifungal formulation have seen great results in the treatment of fungal infections. Over the conventional dosage forms, these topical drug delivery formulations have more benefits along with their extrao

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10

Sari, Rafika. "AKTIVITAS INFUSA KULIT DAUN LIDAH BUAYA (ALOE VERA L.) SEBAGAI PENGOBATAN INFEKSI JAMUR." Jurnal Analis Farmasi 6, no. 2 (2022): 114–21. http://dx.doi.org/10.33024/jaf.v6i2.5950.

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Dermatophytosis is an infection of tissue containing horny substances, such as the stratum corneum in the epidermis, hair, and nails. The infection is caused by the fungus of the genus Trichophyton, one of which is Trichophyton mentagrophytes. Aloe vera leaves contain saponins and flavonoids which are known to have an antimicrobial effect and inhibit fungi. Antifungal products can be processed in various dosage forms, one of which is spray. This study aims to determine the ability of the preparation of aloe vera L. leaf spray in killing T. mentagrophytes. Aloe vera leaves are made using the in

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11

Dhimmar, Bhakti, Rahul Pokale, Mohamed Rahamathulla, et al. "Newfangled Topical Film-Forming Solution for Facilitated Antifungal Therapy: Design, Development, Characterization, and In Vitro Evaluation." Polymers 15, no. 4 (2023): 1003. http://dx.doi.org/10.3390/polym15041003.

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Luliconazole is a broad-spectrum topical antifungal agent that acts by altering the synthesis of fungi cell membranes. Literature suggests that the recurrence of fungal infection can be avoided by altering the pH of the site of infection. Studies have also suggested that fungi thrive by altering skin pH to be slightly acidic, i.e., pH 3–5. The current study is aimed to design, develop, characterize, and evaluate an alkaline pH-based antifungal spray solution for antifungal effects. Luliconazole was used as an antifungal agent and an alkaline spray was formulated for topical application by usin

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Latake, S. B., P. M. Katkar, and V. S. Shinde. "Eco-Friendly Management Of Early Blight Of Tomato Caused By Alternaria Solani." Journal of Plant Disease Sciences 17, no. 1 (2022): 73–78. http://dx.doi.org/10.48165/jpds.2022.1714.

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Aqueous plant extract from ten plant species were tested for antifungal activity against Alternaria solani, whichcauses early blight disease in tomato, in vitro and in the field. At 5, 10 and 15% concentrations, all the aqueous plant extracts inhibited mycelial growth of growth of A. solani significantly better than control. Ginger officinale inhibitedA. solani mycelial growth to the greatest extent. It was followed by Azadirchta indica and Allium sativum.Under field conditions, three sprays of aqueous plant extracts at 15-day intervals were found effective in reducing early blight disease int

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Rezaldi, Firman, Rusmana Rusmana, Susiyanti Susiyanti, et al. "Bioteknologi Kombucha Bunga Telang Sebagai Formulasi dan Sediaan Spray dalam Menghambat Pertumbuhan Fungi Fusarium solani Penyebab Penyakit Tanaman Komoditas Hortikultura." JURNAL BIOS LOGOS 13, no. 3 (2023): 254–65. http://dx.doi.org/10.35799/jbl.v13i3.52017.

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Based on the results of previous research, butterfly pea flower kombucha has been proven that apart from being able to be used as a probiotic drink to enhance the immune system, it can be used as an active ingredient in medicines and cosmetics, a raw material for organic liquid fertilizer, and also in formulations and spray preparations designed to inhibit the growth of pathogenic fungi that cause wilt. concave, and brownish on the stems of horticultural commodity plants. This research aims to make a fermented solution of butterfly pea flower kombucha as a formulation and spray preparation des

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Di Vito, Maura, Lara Vergari, Melinda Mariotti, et al. "Anti-Mold Effectiveness of a Green Emulsion Based on Citrus aurantium Hydrolate and Cinnamomum zeylanicum Essential Oil for the Modern Paintings Restoration." Microorganisms 10, no. 2 (2022): 205. http://dx.doi.org/10.3390/microorganisms10020205.

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A modern painting is characterized by multi-material bases extremely exposed to biodeteriogenic attacks. The aim of this work was to test the antifungal effectiveness of a natural, eco-friendly, and safe emulsion based on Citrus aurantium L. var. amara hydrolate and Cinnamomum zeylanicum Blume (from bark) essential oil, named “Zeylantium green emulsion” (Zege), on modern paintings. Colored unaged and aged canvas samples, performed with modern techniques (acrylic, vinylic and alkyd), were used to test in vitro both the antifungal effectiveness of Zege and its impact on the chemical–physical cha

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Janani, P., A. M. Anandakumar, M. Kabilan, et al. "Comparative Evaluation of Changes in Biochemical Compounds in Tomato Plant (Solanum lycopersicum L.) Infected by Phytophthora infestans and in Response to Antifungal Plant Extracts." Archives of Current Research International 25, no. 6 (2025): 530–39. https://doi.org/10.9734/acri/2025/v25i61298.

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Late blight, caused by the oomycete’s fungi Phytophthora infestans, is one of the most destructive diseases affecting tomato (Solanum lycopersicum L.) crops worldwide. Herbal-based foliar sprays derived from plant extracts offer an eco-friendly, biodegradable alternative to chemical fungicides for managing fungal diseases in crops like Solanum lycopersicum (tomato). This study examines significant alterations in carbohydrates, proteins, total free amino acids, total free fatty acids, phenolic content, and chlorophyll levels in tomato plants subjected to late blight infection and subsequent tre

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Pratami, Diah Kartika, Teti Indrawati, Iis Istikomah, Siti Farida, Paksi Pujianto, and Muhamad Sahlan. "Antifungal activity of microcapsule propolis from Tetragonula spp. to Candida albicans." Communications in Science and Technology 5, no. 1 (2020): 16–21. http://dx.doi.org/10.21924/cst.5.1.2020.178.

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Propolis is a mixture of resin and saliva of Tetragonula spp. that have antifungal activity. The purpose of this study was to develop spray-dried microcapsule propolis (SDMP) and to analyze its antifungal activity to Candida albicans. The SDMP was obtained using a spray drying method by maltodextrin and gum arabic coating. The antifungal activity of SDMP of rough propolis (taken from the outside beehive) and smooth propolis (taken from the inside beehive) was analyzed. The macroscopic characterization showed that SDMP has a powder form with brownish-yellow color. The microscopic characterizati

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17

Deng, Hongying, Chen Yang, Zhenzhu Zhang, et al. "Optimising Fungal Spore Cultivation and Inoculation Methods for Enhanced Antifungal Performance Testing of Textiles." Textile & Leather Review 8 (January 17, 2025): 19–37. https://doi.org/10.31881/tlr.2024.166.

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To improve the precision and operability of antifungal performance testing, this study systematically examines the cultivation time, spore suspension preparation, and inoculation protocols for fungal spores commonly used in mildew and rot resistance testing. Key optimisations were achieved in inoculum time, centrifugation conditions, and spray inoculation methods, enhancing experimental reliability. The findings indicate that Aspergillus brasiliensis and Trichoderma lignorum spores form abundantly within 5–7 days, while Chaetomium globosum requires 17–20 days. Penicillium funiculosum, Aureobas

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18

Hamishehkar, Hamed, Maryam Pourtahmaseb, Afshin Babazadeh, and Shohreh Alipour. "Physicochemical and Aerosolization Assessment of Inhalable Spray Dried Fluconazole Powder." Pharmaceutical Sciences 24, no. 3 (2018): 219–26. http://dx.doi.org/10.15171/ps.2018.32.

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Background: Respiratory fungal diseases therapy is still facing challenges as a result of increasing autoimmune disorders, cancers, and immunosuppressive medication usage. Fluconazole is a wide spectrum antifungal agent and is still used successfully in the treatment of opportunistic infections in combination with other antifungal agents. Since, the treatment of respiratory fungal diseases requires prolonged hospitalization; it may increase the chances of other opportunistic infections. Considering the reported drug resistance and adverse effects of systemic administration, it appears that loc

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Berber Orcen, Buse, Canan Yagmur Karakas, Arda Orcen, Mohamad Amjad Tulimat, and Rabia Cakir. "Microencapsulation of Yeast Cells and Its Potential Usage as a Post-Harvest Biocontrol Agent for Citrus Storage." Agronomy 14, no. 7 (2024): 1431. http://dx.doi.org/10.3390/agronomy14071431.

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In this study, yeasts isolated from citrus groves, trees and leaves were identified, phylogenetic analyzes were performed and their antifungal effects were determined. Wickerhamomyces anamolus (M72), Meyerozyma guilliermondii (M77), and Pichia kudriavzevii (M74) species were identified and were found to have antifungal effects against P. digitatum and P. italicum. Pichia kudriavzevii (M74), which has the highest antifungal effect, showed 67% and 62% inhibition rates against P. digitatum and P. italicum, respectively. An encapsulation study was carried out using a microencapsulation process to

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Sandhya, Dr J., and Neelamegam M. "Bio Synthesis of Nanoparticles from Bio Waste and Its Application on Anti Corrosion, Antifungal and Paint Applications." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 04 (2025): 1–9. https://doi.org/10.55041/ijsrem44611.

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This study demonstrates the green synthesis of zinc oxide (ZnO) nanoparticles using pomegranate and orange peel extracts, with pomegranate proving more effective based on a UV-Vis absorption peak at 390 nm. SEM and DLS analyses revealed nanoparticle sizes ranging from 100–250 nm and an average hydrodynamic diameter of 238.7 nm (PDI 0.296). FTIR confirmed the presence of phytochemical capping agents, while XRD validated a hexagonal wurtzite structure. The nanoparticles exhibited strong antifungal activity, with 100 µL of ZnO formulation producing inhibition zones of 12 mm and 15 mm against Aspe

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Sandhya, Dr J., and Neelamegam M. "Bio Synthesis of Nanoparticles from Bio Waste and Its Application on Anti Corrosion, Antifungal and Paint Applications." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 04 (2025): 1–9. https://doi.org/10.55041/ijsrem44610.

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This study demonstrates the green synthesis of zinc oxide (ZnO) nanoparticles using pomegranate and orange peel extracts, with pomegranate proving more effective based on a UV-Vis absorption peak at 390 nm. SEM and DLS analyses revealed nanoparticle sizes ranging from 100–250 nm and an average hydrodynamic diameter of 238.7 nm (PDI 0.296). FTIR confirmed the presence of phytochemical capping agents, while XRD validated a hexagonal wurtzite structure. The nanoparticles exhibited strong antifungal activity, with 100 µL of ZnO formulation producing inhibition zones of 12 mm and 15 mm against Aspe

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Thakar, Angira, Mrunali Patel, Ankita Badlawala, and Priti Patel. "STUDY OF MYCOTOXIC EFFECT AND CONTROL OF ASPERGILLUS NIGER INFECTION IN LEGUMINOSAE (FABACEAE) WITH SPECIAL REFERENCE TO ARACHIS HYPOGAEA." Journal of Advanced Scientific Research 12, no. 03 (2021): 133–37. http://dx.doi.org/10.55218/jasr.202112319.

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The strain of fungus namely Aspergillus niger was isolated from infected groundnut crop field, collection from Rajasthan Agricultural Research Institute, Durgapura, Jaipur. A number of fungicides were assayed for antifungal efficacy. The fungicides like Carbendazim, Mancozeb, kemoxyl and Antracol were used and they showed different antifungal activity against isolated infectious crop. The treatment of spray and drenching of different fungicide were observed and infected Leguminosae plant was recovered by the effect of fungicide. The best antifungal activity was observed in Antracol fungicide s

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Nurfatimah, Baiq Aluh, Fatya Kamila Putri, Adila Rizkika, Early Windary Suhayatman, and Sucilawaty Ridwan. "Formulasi dan Uji Aktivitas Nanoemulsi Spray Gel Propolis sebagai Antijamur terhadap Candida albicans." Jurnal Sains dan Kesehatan 6, no. 1 (2024): 44–52. http://dx.doi.org/10.25026/jsk.v6i1.2121.

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Aphthous stomatitis is inflammation of the oral mucosa, which can cause pain and discomfort. Thrush can be caused by Candida albicans. So, this research aims to make a nanoemulsion spray gel preparation that can treat the Candida albicans fungus. The method was to formulate propolis nanoemulsion and gel base with variations of Carbopol, followed by physical properties testing such as organoleptic test, pH, viscosity, spreadability and adhesivity, particle size, and index polydispersity. Furthermore, the antifungal activity of the preparation was tested against Candida albicans. The results sho

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Djami-Tchatchou, Arnaud Thierry, Meenakshi Tetorya, James Godwin, Jennette M. Codjoe, Hui Li, and Dilip M. Shah. "Small Cationic Cysteine-Rich Defensin-Derived Antifungal Peptide Controls White Mold in Soybean." Journal of Fungi 9, no. 9 (2023): 873. http://dx.doi.org/10.3390/jof9090873.

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White mold disease caused by a necrotrophic ascomycete pathogen Sclerotinia sclerotiorum results in serious economic losses of soybean yield in the USA. Lack of effective genetic resistance to this disease in soybean germplasm and increasing pathogen resistance to fungicides makes white mold difficult to manage. Small cysteine-rich antifungal peptides with multi-faceted modes of action possess potential for development as sustainable spray-on bio-fungicides. We have previously reported that GMA4CG_V6 peptide, a 17-amino acid variant of the MtDef4 defensin-derived peptide GMA4CG containing the

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Szekalska, Marta, Magdalena Wróblewska, Anna Czajkowska-Kośnik, et al. "The Spray-Dried Alginate/Gelatin Microparticles with Luliconazole as Mucoadhesive Drug Delivery System." Materials 16, no. 1 (2023): 403. http://dx.doi.org/10.3390/ma16010403.

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Candida species are opportunistic fungi, which are primary causative agents of vulvovaginal candidiasis. The cure of candidiasis is difficult, lengthy, and associated with the fungi resistivity. Therefore, the research for novel active substances and unconventional drug delivery systems providing effective and safe treatment is still an active subject. Microparticles, as multicompartment dosage forms due to larger areas, provide short passage of drug diffusion, which might improve drug therapeutic efficiency. Sodium alginate is a natural polymer from a polysaccharide group, possessing swelling

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Silva, Pollyne Amorim, Maria José Cristiane da Silva, Maria Fernanda da Silva, et al. "Pre-formulation study and evaluation of antifungal activity for Clarisia racemosa sporotrichosis." Concilium 23, no. 21 (2023): 881–906. http://dx.doi.org/10.53660/clm-2428-23s33.

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Antifungal therapy can generally cause toxicity and resistance to fungi, therefore the search for new therapies is necessary to minimize the occurrence of these cases. The objective of this work was to carry out an evaluation of antifungal activity and a pre-formulation study based on C. racemosa for sporotrichosis. The plant drug based on C. racemosa, the hydroalcoholic extract, the extracts dried by spray dryer and dried by fluidized bed were obtained and analyzed physicochemically, in addition to evaluating the antifungal activity of the extracts for Sporothrix. Two pharmaceutical forms wer

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Kutasevych, Yanina, I. O. Oliinyk, and K. G. Suprun. "PREVENTION OF FUNGAL INFECTION OF THE FEET." Dermatology and Venerology, no. 3 (2021): 12–15. http://dx.doi.org/10.33743/2308-1066-2021-3-12-15.

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The objective of the work: to study the antifungal activity in vitro and to determine the effectiveness of using the spray containing 0.2% climbazole for the prevention of fungal infections of the feet. Materials and methods. 47 patients were under observation who received treatment at the clinic of the State Establishment «Institute of Dermatology and Venereology of NAMS of Ukraine» for mycosis of the feet and were discharged in a state of recovery, confirmed by mycological negativity. When discharged, patients with a preventive purpose were recommended to apply a spray containing 0.2% climba

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Ahsan, Taswar, Chunhao Liang, Shuyi Yu, et al. "Screening and Optimization of Fermentation Medium for Bacillus velezensis BP-1 and Its Biocontrol Effects against Peyronellaea arachidicola." Applied Sciences 13, no. 8 (2023): 4653. http://dx.doi.org/10.3390/app13084653.

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In the submerged fermentation process, the introduction of novel nutrient media as sources of carbon and nitrogen can enhance antifungal activity. In this study, we used a submerged fermentation process to find the optimal media for the Bacillus velezensis BP-1 strain to grow in, and that would boost its antifungal activity against Peyronellaea arachidicola. By using a single-factor test and central composite design (CCD) in the response surface methodology, the optimal fermentation medium for the B. velezensis BP-1 strain was identified. The antagonistic potential of B. velezensis BP-1 was as

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Almansour, Khaled, Iman M. Alfagih, Alhassan H. Aodah, et al. "Inhalable, Spray-Dried Terbinafine Microparticles for Management of Pulmonary Fungal Infections: Optimization of the Excipient Composition and Selection of an Inhalation Device." Pharmaceutics 14, no. 1 (2021): 87. http://dx.doi.org/10.3390/pharmaceutics14010087.

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Terbinafine is a broad-spectrum antifungal agent with therapeutic potential against pulmonary aspergillosis. The main aim of the current study was to investigate the potential of l-leucine, alone and in combination with mannitol, to improve the performance of spray-dried terbinafine microparticles for inhalation. The study also aimed to investigate the potential of the low resistance Cyclohaler® and the high resistance Handihaler® as inhalation devices for spray-dried microparticles. To this end, eight powder inhalation formulations of terbinafine were prepared by nano spray drying via a facto

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Lafuente, Carla, Jorge Calpe, Leonardo Musto, et al. "Preparation of Sourdoughs Fermented with Isolated Lactic Acid Bacteria and Characterization of Their Antifungal Properties." Foods 12, no. 4 (2023): 686. http://dx.doi.org/10.3390/foods12040686.

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Traditional sourdough is obtained using a mixture of flour and water stored at room temperature until acidification. Therefore, adding lactic acid bacteria (LAB) can improve the quality and safety of sourdough bread. Faced with this problem, four drying techniques—freeze-drying, spray-drying, low-temperature drying, and drying at low humidity—have been applied. Our goals were to isolate LAB strains with antifungal potential against Aspergillus and Penicillium fungi. The antifungal capacity was evaluated with agar diffusion, co-culture in overlay agar, and a microdilution susceptibility assay.

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Fernandes, Luciana P., Izabel C. C. Turatti, Norberto P. Lopes, Joseane C. Ferreira, Regina C. Candido, and Wanderley P. Oliveira. "Volatile Retention and Antifungal Properties of Spray-Dried Microparticles ofLippia sidoidesEssential Oil." Drying Technology 26, no. 12 (2008): 1534–42. http://dx.doi.org/10.1080/07373930802464034.

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Helbling, A., A. Baumann, C. Hänni, and M. Caversaccio. "Amphotericin B nasal spray has no effect on nasal polyps." Journal of Laryngology & Otology 120, no. 12 (2006): 1023–25. http://dx.doi.org/10.1017/s0022215106002167.

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Nasal polyps and chronic rhinosinusitis are the products of an inflammatory process. Recently, fungal involvement has been thought to stimulate the development of polyps, and administration of antifungal agents was therefore considered a potential treatment. Several studies have been published indicating amphotericin B as an effective treatment for nasal polyps and chronic rhinosinusitis. The aim of our investigation was to evaluate the efficacy of intranasal applied amphotericin B on the growth of nasal polyps in a three-month, prospective, open trial. Our results show that nasal amphotericin

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Dubin, Marc G., Cindy Liu, Sandra Y. Lin, and Brent A. Senior. "American Rhinologic Society Member Survey on “Maximal Medical Therapy” for Chronic Rhinosinusitis." American Journal of Rhinology 21, no. 4 (2007): 483–88. http://dx.doi.org/10.2500/ajr.2007.21.3047.

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Background “Maximal medical therapy” is the standard of care for chronic rhinosinusitis (CRS) treatment before the recommendation for surgery. However, this therapy is not consistent. Therefore, as a first step in determining the role of the disparate “maximal medical” treatments for CRS, American Rhinologic Society (ARS) members were surveyed. Methods A survey was mailed to all nonresident members of the ARS (n = 723). Focusing on the time period before surgical intervention is first considered for CRS patients, the survey assessed types of therapies, frequency of use, details on antibiotic a

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COSTA, E., N. TEIXIDÓ, J. USALL, et al. "Survival of Pantoea agglomerans Strain CPA-2 in a Spray-Drying Process." Journal of Food Protection 65, no. 1 (2002): 185–91. http://dx.doi.org/10.4315/0362-028x-65.1.185.

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Spray drying could be a suitable method for preserving microorganisms, as it allows large quantities of cultures to be dried at low cost. The aims of this paper were to evaluate the effects of spray-drying conditions on survival of the biocontrol agent Pantoea agglomerans CPA-2, which has shown antifungal activity against Penicillium expansum and Penicillium digitatum on citrus fruits. Various compounds cited in the bibliography as carriers were tested in our spray drying, and some salts (MgSO4, K2SO4, and Na2CO3) and dairy products (lactoserum or nonfat skimmed milk [NFSM]) showed the best re

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Nuraeni, Santi, Safira Rahmadanti, Aldi Fadilah, and Husnawati. "The Spray of Pegagan Leaf Extract as an Antifungal of Vulvovaginal Candidiasis: A Narrative Review." Current Biochemistry 7, no. 2 (2020): 81–93. http://dx.doi.org/10.29244/cb.7.2.5.

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Vulvovaginal Candidiasis (VVC) is a type of infection caused by the fungus Candida spp. The treatment of candidiasis usually uses antifungal drugs on Candida albicans. Pegagan (Centella asiatica (L.) Urban) is one of wild plants that have been used by the community as a drug. The content of secondary metabolite compounds found in pegagan, such as triterpenoids, alkaloids, flavonoids, and saponins can act as antifungal agents. A literature review in the form of national, international journals and digital books originated from various sites is carried out online. The result of the narrative ana

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Mathpal, Divita, Tarun Garg, Goutam Rath, and Amit Goyal. "Development and Characterization of Spray Dried Microparticles for Pulmonary Delivery of Antifungal Drug." Current Drug Delivery 12, no. 4 (2015): 464–71. http://dx.doi.org/10.2174/1567201812666150326110821.

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Perawati, Santi, Aprilia Wulandari, Silvi Febri Aryani, and Hasma Andani. "Formulation and Activity Test of Foot Spray from Sungkai Leaf Extract (PeronemacanescensJack) as an Antibacterial that Causes Foot Odor." Riset Informasi Kesehatan 12, no. 2 (2023): 221. http://dx.doi.org/10.30644/rik.v12i2.815.

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Background : Sungkai is one of the medicinal plants used by the Suku Anak Dalam Tribe in Jambi to treat infectious diseases. Sungkai leaves contain secondary metabolites including alkaloids, flavonoids, terpenoids, steroids and tannins. Tannins and terpenoids are metabolites that have potential as antifungal , antibacterial and antiviral so they can be used in the cosmetics and pharmaceutical industries. Some bacterial infections can cause foot odor which can reduce a person's self-confidence. The aim of this research was to test Sungkai leaf extract which was formulated in foot spray dosage f

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Szekalska, Marta, Aleksandra Citkowska, Magdalena Wróblewska, and Katarzyna Winnicka. "The Impact of Gelatin on the Pharmaceutical Characteristics of Fucoidan Microspheres with Posaconazole." Materials 14, no. 15 (2021): 4087. http://dx.doi.org/10.3390/ma14154087.

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Fungal infections and invasive mycoses, despite the continuous medicine progress, are an important globally therapeutic problem. Multicompartment dosage formulations (e.g., microparticles) ensure a short drug diffusion way and high surface area of drug release, which as a consequence can provide improvement of therapeutic efficiency compared to the traditional drug dosage forms. As fucoidan is promising component with wide biological activity per se, the aim of this study was to prepare fucospheres (fucoidan microparticles) and fucoidan/gelatin microparticles with posaconazole using the one-st

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Loron, Anne, Vesta Navikaitė-Šnipaitienė, Deimantė Rosliuk, Ramunė Rutkaitė, Christian Gardrat, and Véronique Coma. "Polysaccharide Matrices for the Encapsulation of Tetrahydrocurcumin—Potential Application as Biopesticide against Fusarium graminearum." Molecules 26, no. 13 (2021): 3873. http://dx.doi.org/10.3390/molecules26133873.

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Cereals are subject to contamination by pathogenic fungi, which damage grains and threaten public health with their mycotoxins. Fusarium graminearum and its mycotoxins, trichothecenes B (TCTBs), are especially targeted in this study. Recently, the increased public and political awareness concerning environmental issues tends to limit the use of traditional fungicides against these pathogens in favor of eco-friendlier alternatives. This study focuses on the development of biofungicides based on the encapsulation of a curcumin derivative, tetrahydrocurcumin (THC), in polysaccharide matrices. Sta

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Hernandez, Christopher, Laura Cadenillas, Céline Mathieu, Jean-Denis Bailly, and Vanessa Durrieu. "Preservation of Mimosa tenuiflora Antiaflatoxigenic Activity Using Microencapsulation by Spray-Drying." Molecules 27, no. 2 (2022): 496. http://dx.doi.org/10.3390/molecules27020496.

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Mimosa tenuiflora aqueous extract (MAE) is rich in phenolic compounds. Among them, condensed tannins have been demonstrated to exhibit a strong antioxidant and antiaflatoxin B1 activities in Aspergillus flavus. Since antioxidant capacity can change with time due to environmental interactions, this study aimed to evaluate the ability of encapsulation by spray-drying of Mimosa tenuiflora aqueous extract to preserve their biological activities through storage. A dry formulation may also facilitate transportation and uses. For that, three different wall materials were used and compared for their e

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Azim, Muhlisun, Puspawan Hariadi, Yuyun Febriani, and Tri Puspita Yuliana. "SKRINING EKSTRAK JAMUR ENDOFIT DARI TANAMAN MELINJO (Gnetum gnemon L.) SEBAGAI KANDIDAT ANTIBAKTERI, ANTIJAMUR DAN ANTIOKSIDAN." Jurnal Ilmu Farmasi dan Farmasi Klinik 19, no. 1 (2022): 32. http://dx.doi.org/10.31942/jiffk.v19i1.6681.

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ABSTRACTEndophytic fungi are potential microorganisms in lead compounds investigation as research objects for antibacterial and antifungal drug candidates. These microorganisms are able to produce various secondary metabolites, moreover they can even be regulated according to the needs of researchers. This is an advantage of endophytic fungi with good adaptability response. This study aims to explore the antibacterial, antifungal and antioxidant activity of endophytic fungi from the branch of the Melinjo tree (Gnetum gnemon L.) by qualitative analysis. This study resulted in 13 potential endop

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Anusuya, Sathiyanarayanan, and Muthukrishnan Sathiyabama. "Effect of Chitosan on Rhizome Rot Disease of Turmeric Caused by Pythium aphanidermatum." ISRN Biotechnology 2014 (March 6, 2014): 1–5. http://dx.doi.org/10.1155/2014/305349.

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Chitosan was evaluated for its potential to induce antifungal hydrolases in susceptible turmeric plant (Curcuma longa L.). Under field conditions, the application of chitosan (crab shell) to turmeric plants by foliar spray method induces defense enzymes such as chitinases and chitosanases. Such an increase in enzyme activity was enhanced by spraying chitosan (0.1% w/v) on leaves of turmeric plants at regular intervals. Gel electrophoresis revealed new chitinase and chitosanase isoforms in leaves of turmeric plants treated with chitosan. Treated turmeric plants showed increased resistance towar

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Velivelli, Siva L. S., Kirk J. Czymmek, Hui Li, Jared B. Shaw, Garry W. Buchko, and Dilip M. Shah. "Antifungal symbiotic peptide NCR044 exhibits unique structure and multifaceted mechanisms of action that confer plant protection." Proceedings of the National Academy of Sciences 117, no. 27 (2020): 16043–54. http://dx.doi.org/10.1073/pnas.2003526117.

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In the indeterminate nodules of a model legumeMedicago truncatula, ∼700 nodule-specific cysteine-rich (NCR) peptides with conserved cysteine signature are expressed. NCR peptides are highly diverse in sequence, and some of these cationic peptides exhibit antimicrobial activity in vitro and in vivo. However, there is a lack of knowledge regarding their structural architecture, antifungal activity, and modes of action against plant fungal pathogens. Here, the three-dimensional NMR structure of the 36-amino acid NCR044 peptide was solved. This unique structure was largely disordered and highly dy

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Ahsan, Taswar, Chaoqun Zang, Shuyi Yu, et al. "Screening, and Optimization of Fermentation Medium to Produce Secondary Metabolites from Bacillus amyloliquefaciens, for the Biocontrol of Early Leaf Spot Disease, and Growth Promoting Effects on Peanut (Arachis hypogaea L.)." Journal of Fungi 8, no. 11 (2022): 1223. http://dx.doi.org/10.3390/jof8111223.

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A novel Bacillus amyloliquefaciens BAM strain, with novel fermentation nutrient mediums and compositions, could produce potent antifungal secondary metabolites, as the existing strains face resistance from fungus pathogens. In the current study, we introduced two novel nutrient mediums for the fermentation process, semolina and peanut root extract, as carbon and nitrogen sources in order to maximize the antifungal effects of B. amyloliquefaciens against Cercaspora arachidichola to control early leaf spot disease in peanuts. Based on a single-factor test and the central composite design of resp

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KONIDALA, SATHISH KUMAR, SIVA SHANMUGAM S, S. NARAYANAN, et al. "Development and Validation of UPLC-MS/MS Method for Simultaneous Determination of Multi-Class Antibiotics, Antivirals and Antifungals in Water." Asian Journal of Chemistry 35, no. 10 (2023): 2509–16. http://dx.doi.org/10.14233/ajchem.2023.28186.

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According to a WHO report, antimicrobial resistance is one of the top 10 health threats. Environmental sources are extremely contaminated with high levels of antibiotics, antivirals and antifungals due to their excessive and unsafe usage. Hence, there is a need to detect and quantitate the antimicrobial agents in water. Consequently, a simultaneous analytical method is developed and validated, employing a solid-phase extraction methodology with an HLB cartridge. This method was utilized to quantify a minimum of twenty different chemicals derived from antibiotics, antivirals and antifungal drug

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Gupta, A. K., I. Ahmad, and R. C. Summerbell. "Comparative efficacies of commonly used disinfectants and antifungal pharmaceutical spray preparations against dermatophytic fungi." Medical Mycology 39, no. 4 (2001): 321–28. http://dx.doi.org/10.1080/mmy.39.4.321.328.

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Liu, Xiaotian, Shuyang Chen, Hao Ding, and James Kit Hon Tsoi. "Antifungal Ability of Novel Silane on Titanium Implant Surface." Coatings 14, no. 10 (2024): 1277. http://dx.doi.org/10.3390/coatings14101277.

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Titanium and its alloys are commonly used in dentistry for implants due to their strength, lightweight nature, durability, corrosion resistance, and biocompatibility. These implants can osseointegrate after surface treatments such as SLA, plasma-spray, and nanotubes, providing a stable foundation for prostheses. However, Candida albicans, an opportunistic fungal pathogen, can threaten the success of titanium dental implants, causing oral infections in vulnerable individuals. A dual novel silane blend of 3-acryloxypropyltrimethoxysilane (ACPS) and bis-1,2-(triethoxysilyl)ethane (BTSE) has been

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Almurshedi, Alanood S., Sarah N. Almarshad, Sarah I. Bukhari, et al. "A Novel Inhalable Dry Powder to Trigger Delivery of Voriconazole for Effective Management of Pulmonary Aspergillosis." Pharmaceutics 16, no. 7 (2024): 897. http://dx.doi.org/10.3390/pharmaceutics16070897.

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Invasive pulmonary aspergillosis (IPA) is a fatal fungal infection with a high mortality rate. Voriconazole (VCZ) is considered a first-line therapy for IPA and shows efficacy in patients for whom other antifungal treatments have been unsuccessful. The objective of this study was to develop a high-potency VCZ-loaded liposomal system in the form of a dry-powder inhaler (DPI) using the spray-drying technique to convert liposomes into a nanocomposite microparticle (NCMP) DPI, formulated using a thin-film hydration technique. The physicochemical properties, including size, morphology, entrapment e

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Tkachenko, N. O., I. V. Bushuieva, R. L. Prytula, V. V. Parchenko, and O. P. Shmatenko. "Justification of a price range for topical antifungal drugs based on patient preferences." Zaporozhye Medical Journal 27, no. 1 (2025): 80–86. https://doi.org/10.14739/2310-1210.2025.1.311194.

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The price factor is an important element when using a therapy management, that is complicated by the deterioration in the socio-economic situation of Ukrainians and the National Health Care system in the middle of war. The aim is to examine patients’ willingness-to-pay for topical antifungal drugs (TAFDs) taking into account their differing consumer characteristics in order to justify the economic component in the development and pharmaceutical market introduction of national drugs and to formulate recommendations for improving the level of pharmaceutical care for patients with fungal skin dis

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Melo, Tahira Souza, Paloma de Barros Henrique, Haliny da Silva Magalhães, Amouni Mohmoud Mourad, and Jan Carlo Morais Oliveira Bertassoni Delorenzi. "Antimicrobial and antioxidant activities of Bromelin Propolis Spray." Brazilian Journal of Health Review 7, no. 5 (2024): e73614. http://dx.doi.org/10.34119/bjhrv7n5-449.

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The indiscriminate use of antibiotics over the last 60 years has led to the development of resistant strains, leading an urgent need for new treatments, new molecules or combinations of products, safety and effective. In this regard, propolis has been used in traditional medicine due its therapeutic effects, such as antibacterial, antifungal and antiseptic, tested in vitro, in vivo and clinically. The aim of this study is to evaluate the antimicrobial and antioxidant activities of a commercial oral flavoring product against bacterial strains of clinical interest from the upper respiratory trac

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