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Dissertations / Theses on the topic 'Antigens Analysis Molecular aspects'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 January 2023

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1

Bianco-Miotto, Tina. "Loss of ABO antigens in haematological malignancies / Tina Bianco-Miotto." Thesis, Adelaide, S.A, 2002. http://hdl.handle.net/2440/21857.

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"May 2002"<br>Includes bibliographical references (leaves 229-251)<br>xv, 251 leaves : ill. (some col.) ; 30 cm.<br>Describes the investigation of the alteration of ABH antigen expression on the surface of red blood cells in patients with haematological malignancies.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 2003

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2

Bianco-Miotto, Tina. "Loss of ABO antigens in haematological malignancies." Adelaide, S.A, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phb578.pdf.

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"May 2002" Includes bibliographical references (leaves 229-251) Describes the investigation of the alteration of ABH antigen expression on the surface of red blood cells in patients with haematological malignancies.

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3

Adeleye, Tolulope Abiodun. "A molecular analysis of the immunological response to mycobacterial antigens." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304066.

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4

Davenport, Miles Philip. "Molecular analysis of HLA associations with infectious disease." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297073.

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5

Nath, Deepa. "cDNA sequence analysis of macrophage molecules." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240654.

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6

Shipman, Robert Charles. "The molecular characterization of a common human myelogenous leukemia-associated antigen (CAMAL)." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/27530.

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Previous studies had demonstrated the presence of the p70 (CAMAL) molecule in human myeloid leukemia cells and the promyelocytic leukemia cell line HL60, but not in equivalent preparations of normal cells (Malcolm et al., 1982, 1984; Shipman et al., 1983; Logan et al., 1984). Subsequent studies demonstrated that the p70 (CAMAL) protein was detectable and expressed in human myeloid leukemia cells and the leukemic cell lines HL60, KG1, K562 and U937. The association of p70 (CAMAL) expression with human myeloid leukemia cells prompted its consideration as a candidate leukemia-associated antigen.

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7

Purins, Leanne Roslyn. "Molecular characterisation of the transcriptional activator, HLYU, of Vibrio cholerae O1 /." Title page, abstract and table of contents only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09php9857.pdf.

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Thesis (Ph.D.)--University of Adelaide, School of Molecular and Biomedical Science , Discipline of Microbiology and Immunology, 2005.<br>"May, 2004" Includes corrigenda. includes bibliographical references (leaves 118-156).

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8

Wright, Andrew. "Molecular analysis of the human antibody response to antigens of Staphylococcus aureus." Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485077.

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Staphylococcus aureus is a significant cause of Gram-positive sepsis and infection in the nosocomial environment, and has given rise to the MRSA 'superbug'. The identification of multi-drug resistant strains of S. aureus has advanced the search for new targets for S. aureus prophylaxis or therapy. Such strategies may include the identification of novel S. aureus vaccine candidates, or the production of antibodies to appropriate S. aureus antigens for passive immunization. Previous studies have identified antibodies specific to the major cell wall antigen peptidoglycan as important in the opson

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9

Guy, Rebecca Ann. "Giardia lamblia : an analysis of trophozoite antigens using monoclonal antibodies." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55696.

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10

Daniels, Craig. "Characterisation of proteins involved in Shigella flexneri O-antigen biosynthesis." Title page, abstract and contents only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phd186.pdf.

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Corrigenda pasted onto back end-papers. Bibliography: leaves 163-182. Analyses the proteins involved in Shigella flexneri O-antigen biosynthesis at the molecular level in order to gain a more concise understanding of the biosynthesis machinery and how it functions.

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11

Ramly, Nur Zazarina. "Molecular analysis on the superfamily of surface antigens from the apicomplexan parasite Eimeria tenella." Thesis, University of Sheffield, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577790.

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The work in this thesis has been involved with molecular and structural analysis on the superfamily of surface antigens from the apicomplexan parasite Eimeria ten ella, which causes coccidiosis in chickens. Infection by Eimeria is thought to involve a role for a superfamily of more than 60 cysteine-rich surface antigens (SAGs) in host-parasite interactions. These cysteine-rich SAGs can be divided into two families each with two clusters (A and Bf C and D) within which considerable sequence similarity can be seen. A representative member of the family, SAG 19 (cluster A), has been over-expresse

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12

Gadd, Stephen J. "Analysis of acute mycloid leukaemia cell surface antigens with monoclonal antibodies." Title page, contents and abstract only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phg123.pdf.

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13

Jaworski, Deborah Carol. "Molecular aspects of early-expressed ixodid tick salivary gland antigens with emphasis on host response to tick feeding /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487694702782423.

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14

Mavris, Maria. "Bacteriophage SfII mediated serotype conversion in Shigella flexneri /." Title page, abstract and contents only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phm4608.pdf.

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15

彭志明 and Chi-ming Pang. "Molecular analysis of the dehalogenase IVa of Burkholderia cepacia MBA4." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31240872.

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16

Macpherson, Debbie Freda. "Characterization of the rfb region of Shigella flexneri /." Title page, abstract and contents only, 1995. http://web4.library.adelaide.edu.au/theses/09PH/09phm172.pdf.

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17

黃鳳如 and Fung-yu Huang. "Molecular and cytogenetic analysis of cervical and vulvar cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B26662188.

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18

Alm, Richard A. "Molecular characterization of the haemolysin determinant of Vibrio cholerae O1 /." Title page, contents and abstract only, 1989. http://web4.library.adelaide.edu.au/theses/09PH/09pha444.pdf.

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Thesis (Ph. D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1990.<br>Includes an appendix of author's previously published papers. Includes bibliographical references (leaves 123-160).

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19

Wang, Yue, and 王悦. "Molecular analysis of mitochondrial DNA alterations in endometrial carcinomas." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B32059127.

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20

Champion-Suntharalingam, K. M. "Aspects of molecular analysis in myeloproliferative disorders and myelodysplastic syndromes." Thesis, Anglia Ruskin University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342919.

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21

Bruiners, Natalie. "Molecular genetic analysis of preterm labour." Thesis, Stellenbosch : Stellenbosch University, 2007. http://hdl.handle.net/10019.1/17741.

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Thesis (MSc)--University of Stellenbosch, 2007.<br>ENGLISH ABSTRACT: The World Health Organisation (WHO) has defined preterm labour as the onset of labour before 37 completed weeks of gestation with an incidence ranging between 5-10%. Although patient care has improved, the rate of preterm birth has slowly been increasing and currently impacts significantly on maternal and fetal mortality and morbidity. The complex condition of preterm labour involves multiple etiologies and risk factors, which complicates the search for candidate markers and / or biomarkers. The aim of this prospective

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22

李耀華 and Yiu-wah Lee. "Molecular genetic analysis of the polyol pathway in diabetic and galactosemic cataracts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31234276.

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23

High, Nicola Jane. "A molecular analysis of Escherichia coli cell surface antigens required for the colonisation of the urinary tract." Thesis, University of Leicester, 1988. http://hdl.handle.net/2381/35385.

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The uropathogenic Escherichia coli strain 20025 (04:K12:H-) elaborates at least four fimbrial antigens, Fy (F14), F12-rel, F13, F1C and secretes the toxin a-haemolysin. The work presented in this thesis demonstrates that the gene clusters encoding these five determinants are located within a 60-70kb region of the 20025 chromosome. The F14 fimbrial antigen produced by 20025 is a novel P-fimbriae serotype and exhibits a different binding specificity to the majority of P-fimbriae. To determine the basis of this apparent difference in cell surface receptor specificty a detailed molecular analysis

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24

Schulte, Kathleen Q. "Mutagenized HLA DNA Constructs: Tools for Validating Molecular HLA Typing Methodologies." Thesis, University of North Texas, 1999. https://digital.library.unt.edu/ark:/67531/metadc500888/.

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This study describes the development and validation of mutagenized cloned DNA constructs, which correspond to the polymorphic regions of the class II region of the HLA complex. The constructs were used to verify the allelic specificity of primers and probes in polymerase chain reaction (PCR)-based HLA typing assays such as Sequence Specific Primers (SSP) and Sequence Specific Oligonucleotide Probes (SSOP). The constructs consisted of the entire polymorphic region of exon 2 of class II HLA allele sequences that included primer annealing sites or probe hybridization sites. An HLA allele sequence

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25

Vessey, S. J. R. "A molecular analysis of the T-cell receptor." Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:87b560f9-b1d6-4b12-9c94-fd1b4de397f6.

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The recognition of MHC-peptide ligands by the T cell receptor (TCR) is central to the induction of the adaptive immune response. This thesis describes the development of a bioassay for TCR recognition which was then used to undertake a molecular analysis of the TCR/MHC-peptide interaction. 1. A TCR-CD3ϛ chimeric receptor was stably expressed in the cell line RBL-2H3 to give the transfectant RBL-008. RBL-008 was shown to exhibit MHC-restricted peptide-specific responses to both cellular and multimerised recombinant HLA-A2-pol peptide targets (Chapter 3). 2. By competitively inhibiting the respo

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26

Butler, Lisa Maree. "Molecular analysis of the human Fas gene in colorectal cancer /." Title page, contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phb9858.pdf.

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27

王曉飛 and Xiaofei Wang. "Molecular characterization and cytogenetic analysis of chicken repetitive DNA sequences." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31239419.

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28

Hui, Wing-sum, and 許永森. "Molecular and mutation analysis of hereditary multiple exostoses." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B42577081.

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29

Cai, Guo Qin 1966. "Molecular genetic analysis of acetoacetate metabolism in Sinorhizobium meliloti." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37876.

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Many bacteria accumulate carbon stores as poly-3-hydroxybutyrate (PHB) when growth is limited but carbon availability is not. This stored carbon can then be utilized during conditions of limited carbon availability. The net PHB accumulation in the cell is dependent on the balance between PHB synthesis and degradation. Sinorhizobium meliloti accumulates PHB in the free-living stage but not in the symbiotic stage. The physiological role of the PHB cycle in S. meliloti is unknown. As a first step to understand the genetics of PHB degradation, transposon-generated mutants that were not able to use

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30

Ma, Huan, and 马欢. "Molecular analysis of ocular adnexal lymphomas in the search for potential biomarkers." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46921655.

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31

Flomerfelt, Francis Andrew. "Molecular genetic analysis of glucocorticoid-induced thymocyte apoptosis." Diss., The University of Arizona, 1994. http://hdl.handle.net/10150/187007.

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I have used a molecular genetic approach to study early events in the gene network that precede apoptotic commitment in glucocorticoid-induced thymocyte apoptosis. A panel of recessive, apoptotic-deficient (Apt⁻) mutants were isolated that are cross resistant to several diverse apoptotic treatments. These results indicated that the signal pathways initiated by glucocorticoids, gamma radiation, and c-AMP analog treatment converge to a common apoptotic pathway. Complementation analysis of Apt⁻ cell lines has defined five independent complementation groups that appear to represent mutations in ge

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32

Yu, Yong Gang. "Molecular genetic analysis of host resistance to soybean mosaic virus." Diss., Virginia Tech, 1994. http://hdl.handle.net/10919/37253.

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33

Remédios, Joana Fortuna dos. "Aspects of molecular ecology of carnivore viruses : sapovirus and coronavirus." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2018. http://hdl.handle.net/10400.5/15510.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Current knowledge on the epidemiology of many pathogens of wild animals is limited and little is known about their genetic diversity, geographic and host species range, and their potential to spread between wild, domestic and human species. This thesis, developed at the Leibniz Institute for Zoo and Wildlife Research, includes two studies that seek to contribute to increase the knowledge in this field. The first study aimed to test the hypothesis that consecutive outbreaks of Sapovirus (SaV) infection in spotted hyenas (Crocuta croc

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34

Zhu, Rui, and 朱睿. "Liver-intestine cadherin (CDH17) in hepatocellular carcinoma: molecular analysis and clinicalimplications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43703793.

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35

Fisher, Scott Andrew. "Clinical and molecular analysis of the hepatitis C virus." University of Western Australia. School of Biomedical, Biomolecular and Chemical Sciences, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0099.

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[Truncated abstract] The hepatitis C virus (HCV) is a significant human pathogen for which there are limited post-infection therapies and no effective vaccine. Research into HCV is notoriously difficult due to the absence of suitable in vitro and in vivo model systems with which to study the virus. Furthermore, our understanding of HCV host interaction is limited and the mechanisms by which it subverts the host immune system remains largely unknown. Due to the difficult nature associated with studying HCV, the work presented in this thesis was designed to addresses a broad range of issues rela

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36

Cullen, Lara Michelle. "Molecular analysis of hereditary haemochromatosis." Thesis, Queensland University of Technology, 1999.

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37

Wang, Yongfeng, and 王永峰. "Molecular analysis of ammonia oxidizing prokaryotes in mangrove wetlands and factors affecting their dynamics." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50434421.

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Ammonia/ammonium-oxidizing prokaryotes (AOPs) play a crucial role in nitrogen transformation in the natural ecosystems including mangrove wetlands. The objectives of the present study were to investigate the spatial and temporal distribution of AOPs in the mangrove wetland sediments in subtropical Hong Kong and their ecophysiology. When AOP communities and abundances in a natural coastal mangrove wetland and a constructed freshwater wetland were compared, the constructed freshwater wetland contained a broader range of phylotypes, higher diversity, more complex community structures, and mor

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38

Campeau, Eric. "Molecular genetics of biotin-dependent enzymes : mutation analysis, expression and biochemical studies." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0019/NQ55308.pdf.

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39

Julies, Monique G. "Molecular-genetic analysis of Hirschsprung's disease in South Africa." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51835.

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Thesis (MSc)--Stellenbosch University, 2000.<br>ENGLISH ABSTRACT: Hirschsprung's disease, or aganglionic megacolon, is a common cause of intestinal obstruction in neonates and is associated with the congenital absence of intrinsic ganglion cells in the myenteric and submucosal plexuses of the gastrointestinal tract. The affected area is usually restricted to the distal part of the colon (short segment disease), but total colonic or intestinal involvement occurs in some patients (long segment disease). DNA analysis was performed on samples from 53 unrelated sporadic HSCR patients to sea

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40

Lee, Kwok-ho, and 李國豪. "Molecular analysis of anammox, AOA and AOB in high nitrogen sediment and wetlands." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45544190.

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41

Xu, Yunhe. "Molecular and diagnostic aspects of the protein p41 of HHV-6 and silencing of the CD46 receptor by RNA interference /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-553-0.

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42

Human, Veronique. "Molecular analysis of genes involved in iron overload implicated in oesophageal cancer." Thesis, Link to the online version, 2007. http://hdl.handle.net/10019/391.

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43

Luo, Shun. "Molecular analysis of glycogen phosphorylase-1 gene expression during the development of dictyostelium discoideum." Diss., Virginia Tech, 1992. http://hdl.handle.net/10919/39711.

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The cellular slime mold, <i><b>Dictyostelium discoideum</i></b>, has two developmentally regulated forms of the enzyme glycogen phosphorylase, which are encoded by two distinct, but related genes (Rutherford, et. aI., 1991). A complementary DNA (cDNA) encoding glycogen phosphorylase-}, gp-l, was isolated from a λgtll expression library made from amoebae stage mRNA. The 5' upstream region of the gp-l gene was cloned by inverted polymerase chain reaction (IPCR) and partial genomic DNA library screening. The gp-l gene was found as one copy or low copy number gene in the <i><b>Dictyostelium</i></b

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44

Lin, Ying Chen, and 林映辰. "Functional analysis of anther-specific genes essential for pollen exine development and male fertility in tobacco." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B50534178.

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In flowering plants, pollen grains are surrounded by extremely strong outer walls providing solid and firm structure for protecting pollen and species-specific interactions with female stigma. The outer wall of pollen, referred to as exine, is composed of sporopollenin polymer, but the composition and synthesis of sporopollenin remains poorly understood. Previous studies have indicated that several genes such as Fatty Acyl-CoA Synthetase (ACOS5), Polyketide Synthases (PKSA and PKSB), and Tetraketide α-Pyrone Reductase (TKPR1) take part in the biosynthesis of sporopollenin in Arabidopsis thali

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45

Bruiners, Natalie. "Investigating the Human-M. tuberculosis interactome to identify the host targets of ESAT-6 and other mycobacterial antigens." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71977.

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Thesis (PhD)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: The causative agent of human tuberculosis, Mycobacterium tuberculosis, is an intracellular pathogen that secretes virulence factors, namely ESAT-6 and CFP-10, as substrates of the ESX-1 secretion system. It is hypothesised that these substrates interact with host proteins in a targeted manner in order to elicit a required immune response, and they have been shown to be involved in processes related to pro-inflammatory responses, necrosis, apoptosis, membrane lysis and cytolysis. However, the biological function of ESX-1 sub

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46

Agenbag, Gloudi. "Molecular genetic analysis of familial breast cancer in South Africa." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019/953.

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47

Zhian, Samaneh. "Molecular Genetic Analysis of CRELD1 in Patients with Heterotaxy Disorder." PDXScholar, 2011. https://pdxscholar.library.pdx.edu/open_access_etds/410.

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Heterotaxy refers to the abnormal arrangement of internal organs in relation to each other. Model organism studies have shown that functions of more than eighty genes are required for normal asymmetric left-right organ development. CRELD1 has been shown to be necessary for proper heart development and mutations in CRELD1 are known to increase risk of cardiac atrioventricular septal defects (AVSD). AVSD is the most common form of heart defect associated with heterotaxy, and we have previously shown that some individuals with heterotaxy-related AVSD have mutations in CRELD1. Therefore, we propos

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48

Chang, Yea-wen, and 張雅雯. "Application of molecular genetic techniques to the study of major histocompatibility complex class II allelic associations with insulin-dependent diabetes mellitus in Chinese." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31213960.

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49

Varga, Andrea Erica. "Molecular characterisation, regulation and evolutionary analysis of uroplakin 1B : a tetraspanin family member /." Title page, errata, table of contents and summary only, 2003. http://hdl.handle.net/2440/37940.

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Uroplakin 1B (UPKIB) is an integral structural protein interacting with uroplakins 1A, 2 and 3 to form hexameric plaques along the bladder lumen in the asymmetric unit membrane of urothelial umbrella cells in humans and other mammals. UPKIB mRNA expression is deregulated in transitional cell carcinomas (TCCs), however the mechanisms of regulation of UPKIB have not been established. Using genome databases, a Xenopus UPKIB homologue was identified. Maximum Parsimony and BAMBE (Bayesian Analysis in Molecular Biology and Evolution) data support a close evolutionary relationship between mammalian a

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50

Halpern, Melissa Dale. "The in vivo and in vitro effects of diethyldithiocarbamate on autoimmune New Zealand Black/White F₁ hybrid, MRL/Mp-lpr/lpr and related and normal murine strains." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184940.

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New Zealand Black/White F₁ hybrid (NZB/W) and MRL/Mp-lpr/lpr (MRL/lpr) mice spontaneously develop a Systemic Lupus Erythematosus-like autoimmune disease. While the primary immunologic defect in the NZB/W is due to B cells, in the MRL/lpr it is a result of T cell abnormalities. Diethyldithiocarbamate (DTC), an agent suggested to enhance T cell function, was used to treat both strains. Weekly treatment of NZB/W mice with 25 mg/kg DTC had no significant effect upon survival or autoantibody levels but did induce changes in cell surface antigen expression. MRL/lpr mice treated with DTC displayed no

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