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Journal articles on the topic 'Antilipidemic agent'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Vishweshwaran, S., G. Sairam, M. Shakilarani, S. Stalin, S. Swaminathan, and K. Uma Maheswari. "Evaluation of Chrysin as an Effective Antilipidemic Agent." Asian Journal of Chemistry 26, no. 9 (2014): 2617–20. http://dx.doi.org/10.14233/ajchem.2014.15759.

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Abbasi, Hana, and Hifzul Kabir. "Unani Perspective and New Researches of Sa’ad ku’fi (Cyperus rotundus): A Review." Journal of Drug Delivery and Therapeutics 8, no. 6 (2018): 378–81. http://dx.doi.org/10.22270/jddt.v8i6.2059.

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Cyperus rotundus L. (cyperaceae) is an important medicinal plant which is used in traditional medicine particularly in Unani system of medicine. It is commonly known as motha which is a lawn grass and grows easily in tropical, subtropical and temperate regions. Major Chemical constituents enclosed with this herb are flavonoids, tannins, glycosides, furochromones, monoterpenes, sesquiterpenes, sitosterol, alkaloids, saponins, terpenoids, essential oils, starch, carbohydrates, protein, separated amino acids and many other secondary metabolites. Different parts of cyperus rotundus have been repor

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Komura, T., K. Takahara, M. Sugano, et al. "Effect of LDL-apheresis on the pharmacokinetics of the lipophilic antilipidemic agent probucol." European Journal of Drug Metabolism and Pharmacokinetics 22, no. 3 (1997): 201–6. http://dx.doi.org/10.1007/bf03189807.

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Thangabalan, Boovizhikannan, Nagarajan Pavithra, Palani Pavitra, Rajendran Rama, seemakurthi Jahnavika, and Nayar Ahmed Zeba. "Reported Estimation techniques for Quantification of Simvastin :- A Review." World Journal of Biology Pharmacy and Health Sciences 12, no. 2 (2022): 079–86. https://doi.org/10.5281/zenodo.7604659.

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Simvastatin is used along with a proper diet to help lower bad cholesterol and fats and raise good cholesterol in the blood. It belongs to a group of drugs known as statins. It works by reducing the amount of cholesterol made by the liver. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. There are various analytical methods for estimation of the drug. This paper list outs the various analytical methods for the drug.

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Bano, Shayara, and Jitender K. Malik. "Chlorogenic Acid a Potent Anti-inflammatory Agent: In-Silico Molecular Docking approach." Middle East Research Journal of Pharmaceutical Sciences 2, no. 1 (2021): 10–20. http://dx.doi.org/10.36348/merjps.2022.v02i01.002.

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Abstract: Chlorogenic acid (5-O-caffeoylquinic acid) is a phenolic compound of the hydroxycinnamic acid family. This polyphenol has many health-enhancing properties, most of which are relevant for the treatment of metabolic syndrome, including antioxidant, anti-inflammatory, antilipidemic, antidiabetic, and antihypertensive effects. In addition, chlorogenic acid has antioxidant properties, especially against lipid oxidation. Protective properties against degradation and prebiotic activity of other bioactive compounds present in foods. In addition, chlorogenic acid has antioxidant properties, e

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Mikhailova, A. A., M. V. Sharypova, A. V. Simanenkova, et al. "Fibroblast growth factor 21: a novel link in the development and treatment of metabolic disorders." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 30, no. 5 (2025): 441–50. https://doi.org/10.18705/1607-419x-2024-2455.

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In recent years, fibroblast growth factor 21 (FGF21) has garnered increasing attention as a metabolic regulator. It plays a role in the development of tissue insulin sensitivity, exerts beneficial effects on carbohydrate and lipid metabolism, and exhibits antihyperglycemic and antilipidemic properties. Elevated FGF21 levels have been observed in patients with type 2 diabetes, obesity, non-alcoholic fatty liver disease, and a range of other conditions. This may indicate either resistance to FGF21 or a compensatory response to metabolic stress. Evidence suggests that FGF21 can be considered both

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Yu, Seungmin, Hee Min Lee, Jangho Lee, Jin-Taek Hwang, Hyo-Kyoung Choi та Yu Geon Lee. "Pennogenin 3-O-β-Chacotrioside Attenuates Hypertrophied Lipid Accumulation by Enhancing Mitochondrial Oxidative Capacity". International Journal of Molecular Sciences 25, № 5 (2024): 2970. http://dx.doi.org/10.3390/ijms25052970.

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Excessive lipid accumulation in adipocytes is a primary contributor to the development of metabolic disorders, including obesity. The consumption of bioactive compounds derived from natural sources has been recognized as being safe and effective in preventing and alleviating obesity. Therefore, we aimed to explore the antilipidemic effects of pennogenin 3-O-β-chacotrioside (P3C), a steroid glycoside, on hypertrophied 3T3-L1 adipocytes. Oil Red O and Nile red staining demonstrated a P3C-induced reduction in lipid droplet accumulation. Additionally, the increased expression of adipogenic and lip

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Madaki, Fatima, Adamu Kabiru, Ogunrombi Clinton, Sakariyau Waheed, and Yunusa Ibrahim. "Evaluating the influence of Trypanosomiasis on murine model using Corchorus olitorius leaf extract as a trypanocidal agent." Bulletin of Natural Sciences Research, no. 00 (2024): 14. http://dx.doi.org/10.5937/bnsr14-51999.

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Trypanosomiasis, a parasitic disease caused by trypanosomes, which are flagellate protozoa transmitted through the bite of the tsetse fly, manifests with symptoms including substantial weight loss, anemia, fever, edema, adenitis, dermatitis, and nervous disorders. This research investigated the impact of trypanosomiasis on a murine model while utilizing Corchorus olitorius leaf extract as a potential trypanocidal agent. An acute toxicity analysis was conducted following Lorke's method, and the antitrypanosomal efficacy was assessed in rats at doses of 100, 200, and 400 mg/kg over three weeks,

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Uma P, Venkatachalam V V, Mani Chandrika P, and Sorabh Kumar Agrawal. "Antidiabetic and Antilipidemic activity of Poly herbal formulation (PHF) in STZ-NA induced diabetes in rats." International Journal of Research in Pharmaceutical Sciences 12, no. 3 (2021): 2239–47. http://dx.doi.org/10.26452/ijrps.v12i3.4844.

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The effects of polyherbal formulations were studied in the streptozotocin-nicotinamide (STZ-NA) induced diabetes rat model. The present study was undertaken to assess the effects of polyherbal formulations on the blood sugar level (BSL) as well as blood lipid level(BLL) of STZ-NA diabetic rats. The leaves of Moringa oleifera and roots of Raphanus raphanistrum were used for the study due to the presence of various phytoconstituents such as alkaloids, saponins, tannins, steroids, phenolic acids, flavonoids. Three polyherbal formulations were prepared from different portions of leaves of Moringa

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10

Uma P, Venkatachalam V V, Mani Chandrika P, and Sorabh Kumar Agrawal. "Antidiabetic and Antilipidemic activity of Poly herbal formulation (PHF) in STZ-NA induced diabetes in rats." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 8092–100. http://dx.doi.org/10.26452/ijrps.v11i4.4844.

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The effects of polyherbal formulations were studied in the streptozotocin-nicotinamide (STZ-NA) induced diabetes rat model. The present study was undertaken to assess the effects of polyherbal formulations on the blood sugar level (BSL) as well as blood lipid level(BLL) of STZ-NA diabetic rats. The leaves of Moringa oleifera and roots of Raphanus raphanistrum were used for the study due to the presence of various phytoconstituents such as alkaloids, saponins, tannins, steroids, phenolic acids, flavonoids. Three polyherbal formulations were prepared from different portions of leaves of Moringa

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11

Ayepola, Omolola R., Nicole L. Brooks, and Oluwafemi O. Oguntibeju. "Kolaviron Improved Resistance to Oxidative Stress and Inflammation in the Blood (Erythrocyte, Serum, and Plasma) of Streptozotocin-Induced Diabetic Rats." Scientific World Journal 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/921080.

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Aims.Bitter kola seed (Garcinia kola, family:Guttiferae) has been used as a social masticatory agent in Africa for several years and is believed to possess many useful medicinal properties. The present study evaluates the antioxidative, anti-inflammatory, and antilipidemic effects of kolaviron (an extract from theGarcinia kolaseeds) in the blood of streptozotocin- (STZ) induced diabetic rats.Methods.Diabetic rats were treated with kolaviron (100 mg/kg b·wt) orally, five times a week for a period of six weeks. Serum glucose andHBA1Cconcentrations were estimated in experimental groups. The activ

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12

Hardoko, Hardoko, Evi K. Harisman, and Yunita E. Puspitasari. "The kombucha from Rhizophora mucronata Lam. herbal tea: Characteristics and the potential as an antidiabetic beverage." Journal of Pharmacy & Pharmacognosy Research 8, no. 1 (2020): 410–21. http://dx.doi.org/10.56499/jppres20.810_8.5.410.

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Context: Kombucha from tea is reported to be beneficial for health. Moreover, it can be used as a hepatoprotective, antiproliferative, antimicrobial, antidiabetic, and antilipidemic agent and is capable of healing stomach ulcers. But kombucha from other herbal has not been studied, including kombucha from the mangrove (Rhizophora mucronata) fruit. Aims: To evaluate the characteristics and the antidiabetic potential of kombucha herbal tea from R. mucronata fruit based on in vitro, chemistry, and physical analysis. Methods: This study was conducted by an experimental method using R. mucronata he

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13

Bae, Jaehyun, Namki Hong, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, and Yong-ho Lee. "Comparison of Renal Effects of Ezetimibe–Statin Combination versus Statin Monotherapy: A Propensity-Score-Matched Analysis." Journal of Clinical Medicine 9, no. 3 (2020): 798. http://dx.doi.org/10.3390/jcm9030798.

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Neither lowering of blood lipid levels nor treatment with statins definitively improves renal outcomes. Ezetimibe, a non-statin antilipidemic agent, is known to not only decrease blood lipid levels but also reduce inflammatory response and activate autophagy. We evaluated the effect of adding ezetimibe to a statin on renal outcome compared with statin monotherapy by analyzing longitudinal data of 4537 patients treated with simvastatin 20 mg plus ezetimibe 10 mg (S + E) or simvastatin 20 mg alone (S) for more than 180 days. A propensity-score-based process was used to match baseline characteris

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14

Mazher, Mubsher, Muhammad Ishtiaq, and Mussaddaq Mazhar. "Effects of green synthesized calcium oxide nanoparticles from extracts of Citrullus colocynthis on body weight, plasma atherogenic index, and histology of liver and stomach of high-fat-diet-fed rats." Archives of Biological Sciences, no. 00 (2023): 24. http://dx.doi.org/10.2298/abs230531024m.

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Citrullus colocynthis has been used to treat obesity and hyperlipidemia. Nanoparticles, due to their nano size, phytochemical adsorption, improved systemic absorption and high bioavailability, can potentially improve the bioactivity of C. colocynthis. The present research focused on studying the effects of green synthesized calcium oxide nanoparticles (CaONPs) from C. colocynthis fruit extracts (CCFE) on the body weight, the atherogenic index of plasma (AIP), and the histopathology of male albino rats. Ethyl??-d-glucopyranoside was the major constituent of CCFE, along with phenols and fatty ac

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15

OHNO, Tomoyasu, Shin-go YANO, Haruo YAMADA, et al. "Synthesis of the Optical Isomers of 4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidine-4-yl]methyloxybenzoic Acid (S-2) and Their Biological Evaluation as Antilipidemic Agent." CHEMICAL & PHARMACEUTICAL BULLETIN 47, no. 11 (1999): 1549–54. http://dx.doi.org/10.1248/cpb.47.1549.

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16

Dighe, Pearl Pires, and Tank Hm. "DESIGN AND STATISTICAL OPTIMIZATION OF A BILAYERED TABLET OF METOPROLOL SUCCINATE SUSTAINED RELEASE AND ATORVASTATIN CALCIUM IMMEDIATE RELEASE: ONCE A DAY FORMULATION IN THE MANAGEMENT OF HYPERTENSION." Asian Journal of Pharmaceutical and Clinical Research 11, no. 3 (2018): 293. http://dx.doi.org/10.22159/ajpcr.2018.v11i3.23528.

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Objective: The current study involves the fabrication of oral bilayer matrix designs of a combination of two drugs, metoprolol succinate and atorvastatin calcium, the optimization of their in vitro release and characterization using the design expert software. Metoprolol succinate, a β1- selective adrenergic receptor blocking agent, is used in the management of hypertension has a half-life of approximately 4–5 h; thus, there is the need to use extended-release formulation for prolonged action. Atorvastatin is a hydroxymethylglutaryl-coenzyme A reductase inhibitor, an antilipidemic, used to low

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17

S, Yusra Tafheem. "An Overview on Composition and Therapeutic Potentials of the Black Seed (Nigella sativa)." International Journal for Research in Applied Science and Engineering Technology 9, no. 12 (2021): 1966–75. http://dx.doi.org/10.22214/ijraset.2021.39246.

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Abstract: Nigella sativa is an annual herbaceous plant that belongs to the Ranunculaceae family and produces seeds known as black seed or black cumin. Black seed has been used in various civilization around the world for centuries to treat various ailments. It is widely used in a variety of traditional medical systems, including Unani, Ayurveda, and Siddha. Black seed is considered to be nutritionally dense, with high levels of fat, protein, dietary fibre, calcium, and iron. The seed is known to have a wide range of pharmacological properties which are supported by numerous studies. Extensive

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18

Abdellah, Reem K., Nadia M. El-Beih, Fatma A. Morsy, Khaled G. Abdel-Wahhab, and Enas A. El-Hussieny. "Moringa (Moringa oleifera) leaves aqueous extract enhances fibronectin type III domain-containing protein 5 gene expression and serum irisin liberation in an obesity model." Egyptian Pharmaceutical Journal 20, no. 1 (2021): 92–103. http://dx.doi.org/10.4103/epj.epj_50_20.

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Background Obesity, a risk agent for many chronic diseases, leads to increased mortality and poses one of the major public health problems. Objective This study aimed to investigate the thermogenic and antiobese efficiency of Moringa aqueous extract (MAE) on obese-modeled rats. Materials and methods Adult male rats (150–170 g) were randomly divided into four groups, with 10 animals each, as follows: (a) healthy rats served as control, (b) healthy rats administrated with MAE (400 mg/kg/day), (c) obese-modeled rats, and (d) obese-modeled rats treated with MAE. Results After 30 consecutive days o

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19

Daniel, Priscilla. "Effect of lupeol on insulin resistance in adipose tissue by modulating the expression of insulin and inflammatory signaling molecules in high-fat diet and sucrose-fed diabetic rats." Bioinformation 19, no. 4 (2023): 445–53. http://dx.doi.org/10.6026/97320630019445.

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The prevalence of obesity and diabetes has increased globally as a result of lifestyle modifications including eating a high-fat diet and not exercising. The target tissues to insulin action are the key pathophysiological event contributing to the development of type 2 diabetes mellitus. The treatments for type 2 diabetes that are now accessible are ineffectual due to their unfavourable side effects. Hence, search drugs, from plant sources. Lupeol is widely present in various medicinal plants. It has been reported to elicit multitude of bioactivities including antilipidemic and antihyperglycem

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Ohno, Tomoyasu, Shin-go Yano, Haruo Yamada, et al. "ChemInform Abstract: Synthesis of the Optical Isomers of 4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidine-4-yl]methyloxybenzoic Acid (S-2) and Their Biological Evaluation as Antilipidemic Agent." ChemInform 31, no. 17 (2010): no. http://dx.doi.org/10.1002/chin.200017119.

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Oyama, Jun-ichi, Fumi Uchida, and Koichi Node. "Do antilipidemic agents reduce blood pressure?" Vascular Failure 2, no. 1 (2018): 6–10. http://dx.doi.org/10.30548/vascfail.2.1_6.

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Xydakis, Antonios M., and Peter H. Jones. "Toxicity of antilipidemic agents: Facts and fictions." Current Atherosclerosis Reports 5, no. 5 (2003): 403–10. http://dx.doi.org/10.1007/s11883-003-0012-3.

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23

Studer, Marco, Matthias Briel, Bernd Leimenstoll, Tracy R. Glass, and Heiner C. Bucher. "Effect of Different Antilipidemic Agents and Diets on Mortality." Archives of Internal Medicine 165, no. 7 (2005): 725. http://dx.doi.org/10.1001/archinte.165.7.725.

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Habib, N. S., та M. A. Khalil. "Antilipidemic Agents, III: Synthesis of Some Heterocyclic Derivatives of β-Sitosterol". Archiv der Pharmazie 323, № 7 (1990): 401–4. http://dx.doi.org/10.1002/ardp.19903230705.

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25

Oh, Seo-hye, Gi-hyeon Gwon, Eun-su Park, Won-young Kim, and Dong-young Kim. "A Case Report on Drug-induced Liver Injury Induced by Antilipidemic Agents." Journal of Internal Korean Medicine 42, no. 5 (2021): 777–83. http://dx.doi.org/10.22246/jikm.2021.42.5.777.

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Objective: This case report describes a patient who suffered a drug-induced liver injury and was treated with <i>Saengganggeonbi-tang</i>.Methods: A patient was treated with Korean herbal medicine, and the treatment effect was evaluated using liver function tests (LFT) to determine total cholesterol and triglyceride levels.Results: The patient’s LFT levels were normal on 27 July 2021 but became abnormal by 12 August 2021 after taking Western drugs. After 15 days of treatment with Saengganggeonbi-tang, the LFT levels had improved.Conclusion: This study shows that <i>Saenggange

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Howard, W. J. "Effect of Different Antilipidemic Agents and Diets on Mortality: A Systematic Review." Yearbook of Endocrinology 2006 (January 2006): 117–18. http://dx.doi.org/10.1016/s0084-3741(08)70318-4.

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Studer, M., M. Briel, B. Leimenstoll, T. R. Glass, and H. C. Bucher. "Effect of Different Antilipidemic Agents and Diets on Mortality. A Systematic Review." ACC Current Journal Review 14, no. 7 (2005): 10–11. http://dx.doi.org/10.1016/j.accreview.2005.06.022.

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Rembold, Christopher M., Rongrong Fan, Karen E. Rembold, and Carlos R. Ayers. "Effectiveness of multiple antilipidemic agents on vertical auto profile ii guided treatment of dyslipoproteinemia." American Journal of Cardiology 90, no. 8 (2002): 887–90. http://dx.doi.org/10.1016/s0002-9149(02)02716-9.

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Oluwafemi Ibukun, Emmanuel, and Gideon Oludare Oladipo. "Lipidomic Modulation in Stressed Albino Rats Is Altered by Yolk and Albumen of Quail (Coturnix japonica) Egg and Poultry Feed." Biochemistry Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/2565178.

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Cold and immobilization stressors can generate oxidative stress as well as skeletal muscle fatigue. Free radicals cause oxidative degradation of lipids, proteins, nucleic acids, and carbohydrates molecules, thereby compromising cell integrity and function. Quail egg had been described as being very functional biochemically, due to the essential biomolecules it contains in very regulated quantity. This study was aimed for evaluating the dietary effect of the egg on lipid profile parameters on selected tissues. The antilipidemic properties of the egg yolk and albumen and poultry (layers) feed we

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Li, Chao, Wei Tang, Shanglong Chen, et al. "Phytochemical Properties and In Vitro Biological Activities of Phenolic Compounds from Flower of Clitoria ternatea L." Molecules 27, no. 19 (2022): 6336. http://dx.doi.org/10.3390/molecules27196336.

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Phenolic compounds from the flower of Clitoria ternatea L. (PCFCTL) were extracted using a high-speed shearing extraction technique and purified by AB-8 macroporous resins, and the phytochemical composition of the purified phenolic compounds from the flower of Clitoria ternatea L. (PPCFCTL) was then analyzed. Subsequently, its bioactivities including antioxidant properties, enzyme inhibitory activities, and antiproliferative activities against several tumor cell lines were evaluated. Results indicated that the contents of total phenolics, flavonoids, flavonols, flavanols, and phenolic acids in

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Lama, Khaled Arfaj Abdulelah Fareed Fattani Areen Jibreel Khamaj Rawan Jabril Khamaj Sultana Sedki H. Alnejaimi Hala Atif Ismail Mohammad Ghazi Al Tamimi Mohamed Maged Mohamed Elmoursi Amjad Mohammed Saati Ghaday Ibrahim Alyamani. "DYSLIPIDEMIA IN DIABETES MELLITUS TYPE 2; PREVALENCE, PATHOPHYSIOLOGY, MANAGEMENT, AND TREATMENT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 17022–28. https://doi.org/10.5281/zenodo.2527570.

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<strong><em>Introduction:</em></strong><em> Recently, the incidence of diabetes mellitus type 2 has been significantly increasing in most parts of the world, with some reports estimating and overall 592 million diabetics in the year 2035.</em> <strong><em>Aim of work: </em></strong><em>In this review, we will review most recent medical literature on dyslipidemia in diabetes mellitus type 2 to discuss prevalence, pathophysiology, management, and treatment of dyslipidemia in these patients.</em> <strong><em>Methodology: </em></strong><em>We did a systematic search for dyslipidemia in diabetes me

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Fortini, Francesca, Francesco Vieceli Dalla Sega, Luisa Marracino, et al. "Well-Known and Novel Players in Endothelial Dysfunction: Updates on a Notch(ed) Landscape." Biomedicines 9, no. 8 (2021): 997. http://dx.doi.org/10.3390/biomedicines9080997.

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Endothelial dysfunction characterizes every aspect of the so-called cardiovascular continuum, a series of events ranging from hypertension to the development of atherosclerosis and, finally, to coronary heart disease, thrombus formation, myocardial infarction, and heart failure. Endothelial dysfunction is the main prognostic factor for the progression of vascular disorders, which responds to drug intervention and lifestyle changes. Virtually all of the drugs used to prevent cardiovascular disorders, such as long-used and new antilipidemic agents and inhibitors of angiotensin enzyme (ACEi), exe

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Lingaiah, Mamidala Estari, and Rao Nagaraja. "Effect of Chloroxylon swietenia Bark Extract On Lipid Profiles Of Diabetic Induced Wistar Rats." Biolife 11, no. 1 (2023): 32–35. https://doi.org/10.5281/zenodo.7698781.

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<strong>Abstract</strong> Diabetes mellitus is a metabolic disorder and not a disease, characterized by hyperglycemia resulting from defects in insulin secretion/synthesis/induction in to the cell and insulin action or both. This investigation was designed to study the anti lipidemic profiles was investigated in diabetic induced Wistar rats treated with plant extract. Diabetes was induced after a single dose of  intraperitoneal injection of Alloxan monohydrate drug (120 mg/ kg). The parameters studied were lipidprofile like Total cholesterol (TC), Triglyceride (TG), High-density lipoprote

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Pereira Gonçalves, Mariana Mendes, Frederico Daldegan, Gabriel Correia Iannuzzi, Marcelo Mendonça Rodrigues, and Seleno Glauber de Jesus-Silva. "Association between weight loss and reduced use of antihypertensive, hypoglycemic, psychotropic, and lipid-lowering drugs in patients undergoing bariatric surgery." REVISTA CIÊNCIAS EM SAÚDE 11, no. 1 (2021): 6–13. http://dx.doi.org/10.21876/rcshci.v11i1.940.

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Objectives: To analyze whether the weight reduction observed in bariatric surgery (Roux-en-Y gastric bypass; BGYR) is accompanied by a reduction in the use of antihypertensive, hypoglycemic, antilipidemic, and psychotropic drugs after 6 and 12 months. Methods: Longitudinal, retrospective study of 100 adult patients undergoing RYGB from May 2015 to January 2019, by laparotomy or laparoscopy. Data on age, body mass index (BMI), and the number of drugs used were recorded 6 and 12 months after surgery. Results: The mean age was 39.7 ± 9.7 years, and the majority were female (n = 78). The mean preo

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Moniruzzaman, Mohammed, Begum Rokeya, Sohel Ahmed, Amrita Bhowmik, Md Khalil, and Siew Gan. "In Vitro Antioxidant Effects of Aloe barbadensis Miller Extracts and the Potential Role of These Extracts as Antidiabetic and Antilipidemic Agents on Streptozotocin-Induced Type 2 Diabetic Model Rats." Molecules 17, no. 11 (2012): 12851–67. http://dx.doi.org/10.3390/molecules171112851.

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Schein, Jeffrey R. "Cigarette Smoking and Clinically Significant Drug Interactions." Annals of Pharmacotherapy 29, no. 11 (1995): 1139–48. http://dx.doi.org/10.1177/106002809502901113.

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Objective: To review clinically significant drug interactions associated with cigarette smoking. Data Sources: Data from scientific literature were identified by using a MEDLINE search. Data were extracted, evaluated, and summarized for this review. Study Selection: Findings and experiences were selected from clinical, epidemiologic, and pharmacokinetic studies; review articles; case studies; abstracts; letters to the editor; and proceedings. Data Extraction: Data from human studies published in English were evaluated. Only interactions deemed clinically significant are included in this review

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Samudio, Ismael, Marina Konopleva, Stephen Safe, and Michael Andreeff. "Guggulsterones Induce Apoptosis and Differentiation in AML: Identification of Isomer-Specific Antileukemic Activities of the Pregnanedienedione Structure." Blood 106, no. 11 (2005): 4466. http://dx.doi.org/10.1182/blood.v106.11.4466.4466.

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Abstract The gum resin from the guggul tree, commiphora mukul, has been used in Ayurvedic medicine for centuries to treat inflammatory and lipid disorders, and an ethylacetate extract of the resin, termed guggulipid, has been reported to have an anti-obesity and antilipidemic effect in clinical trials with no significant toxicity. In this study, we investigate the antileukemic effects of the active components in guggulipid, namely cis- and trans-guggulsterone (cGS and tGS, respectively), and compare their effects to those of the unrelated structural isomer 16-dehyroprogesterone (P). Our result

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Saad, Enas A., Hanaa A. Hassan, Mamdooh H. Ghoneum, and Mai Alaa El-Dein. "Edible wild plants, chicory and purslane, alleviated diabetic testicular dysfunction, and insulin resistance via suppression 8OHdg and oxidative stress in rats." PLOS ONE 19, no. 4 (2024): e0301454. http://dx.doi.org/10.1371/journal.pone.0301454.

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Testicular dysfunction is a prevalent health problem frequently reported in individuals with diabetes mellitus (DM). Oxidative-inflammatory reactions, hormonal and spermatic abnormalities often accompany this illness. Herbal remedies “particularly wild plants” including chicory (Chicorium Intybus) and purslane (Portulaca Oleracea) are emerging as popular agents for people dealing with these issues due to their ability to act as antioxidants, reduce inflammation, and exhibit antidiabetic effects. According to the collected data, the daily administration of chicory (Ch) seed-extract (250 mg/kg)

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Okon, Michael Edet, Edet Okon Umoh, and Michael Akachukwu Onyenweze. "The Effect of Methanolic Extract of Costus afer Leaves on the Lipid Profile of Chronically Stressed and Non-Stressed Male Wistar Rats." GPH-International Journal of Biological & Medicine Science 7, no. 10 (2024): 41–73. https://doi.org/10.5281/zenodo.14238170.

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The present study was conducted to investigate the effects of the methanolic extract of <em>Costus afer</em> leaves on the lipid profile of chronically stressed and non-stressed Wistar rats. A total of 30 male Wistar rats, weighing 180–220 g, were used for the study. The rats were divided into six (6) groups: Control group (CT), Stress group (STR), <em>Costus afer</em> 200 mg/kg body weight (CA1), <em>Costus afer</em> 400 mg/kg body weight (CA2), Stress + <em>Costus afer</em> 200 mg/kg body weight (STR + CA1), and Stress + <em>Costus afer</em> 400 mg/kg body weight (STR + CA2). The anima

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Mishra, Rosaline, Divya Juyal, and S. Sadish Kumar. "Smilax zeylanica: A Promising Antilipidemix and Antiobesity Agent." Journal of Pharmaceutical Research International, August 30, 2021, 342–62. http://dx.doi.org/10.9734/jpri/2021/v33i42a32413.

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Background: It is well established fact that obesity has now said to be a disease status.The phytochemicals have always been looked for their enormous stored potential. Similax zeylanica is a naturally occurring flavonoid known for its pharmacological potential. In this study it was aimed to determine the antiobesity and antilipidemic effect of various Similax zeylanica extract. Materials and Methods: The pharmacological screening of Cyclohexane extract of Smilax zeylanica (SZH), ethyl acetate extract Smilax zeylanica (SZE) and methanolic extract of Smilax zeylanica (SZM) was performed.

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Bhokardankar, Prashant Sakharam. "An over view of medicinal uses of Ayurvedic drug Pippali (piper longum)." National Journal of Research in Ayurved Science 7, no. 4 (2019). http://dx.doi.org/10.52482/ayurlog.v7i4.391.

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Background: Pippali, Piper longum (P.longum) usually called pippali which is a member of the Piperaceae family, is frequently used medicinal herb in Ayurved, Unani & Siddha system of medicine. In traditional medicine world it is being used to treat most of the systemic disorders. This systematic review was conducted with an objective to search, explore & compile the phytochemical constituents & their efficacies both in modern and traditional part to understand as a potential therapeutic agent. Material & method: Published details scientific literature on P. Longum by various re

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Kalita, Himadri, Dulal C. Boruah, Meetali Deori, et al. "Antidiabetic and Antilipidemic Effect of Musa balbisiana Root Extract: A Potent Agent for Glucose Homeostasis in Streptozotocin-Induced Diabetic Rat." Frontiers in Pharmacology 7 (May 2, 2016). http://dx.doi.org/10.3389/fphar.2016.00102.

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Nwankwo, L. U., F. A. Onyegbule, C. C. Abba, and E. Agbamu. "Comparative Hypolipidemic Evaluation of Aframomum Melegueta Seeds and Moringa Oleifera Leaves." Journal of Pharmaceutical Research International, December 16, 2021, 166–82. http://dx.doi.org/10.9734/jpri/2021/v33i59a34261.

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Aims: The study was carried out to compare the lipid lowering effects of both crude drugs as well as deducing the extracts with the best lipid lowering property; and the fractions. Study Design: The research was conducted with an experimental design solely based on laboratory trials which involved the use of ninety-six (96) male albino wistar rats to compare the hypolipidemic effects of both crude drugs and respective fractions. Place and Duration of Study: Department of Pharmacognosy Laboratory, Faculty of Pharmacy, Delta State University, Abraka, Nigeria and Department of Pharmac

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Irfan, N., Prakash Vaithyanathan, Harishchander Anandaram, S. Mohammed Zaidh, S. Priya Varshini, and A. Puratchikody. "Active and allosteric site binding MM-QM studies of Methylidene tetracyclo derivative in PCSK9 protein intended to make a safe antilipidemic agent." Journal of Biomolecular Structure and Dynamics, July 26, 2023, 1–10. http://dx.doi.org/10.1080/07391102.2023.2239928.

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Ashfaq, Maimoona, Misbah Arshad, and Bahisht Rizwan. "Pharmacological Potential of Sweet Violet (Banafsha) on Human Body." DIET FACTOR (Journal of Nutritional & Food Sciences), June 30, 2021, 30–36. http://dx.doi.org/10.54393/df.v2i01.42.

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Sweet violet commonly known as Gul-e-Bafasha or Banafsha is a herb widely used as ethnomedicine in dried form in Pakistan for the treatment of various disease or symptoms. Viola odorata had phytochemicals constituents (flavonoids, flavanols, ascorbic acid, phenolics) and antioxidative property Objective: The goal of this research is to emphasize Viola Odorat's (Gul-e-Banafsha) therapeutic benefits on human health. Methods: This review literature is assessed from the previous data available from google scholar, Medline and PubMed. After going through the published articles, researches and liter

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Gheet, Fatma Sayed, Heba El-Sayed Dawoud, Waleed Ahmed El-Shahaby, Shymaa Mohamed Elrifaey, and Hend Hassan Abdelnabi. "Hydroxychloroquine in children with proliferative lupus nephritis: a randomized clinical trial." European Journal of Pediatrics, February 8, 2023. http://dx.doi.org/10.1007/s00431-023-04837-0.

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AbstractHydroxychloroquine (HCQ) is an antimalarial agent used to treat mucocutaneous, musculoskeletal, constitutional manifestations of systemic lupus erythematosus (SLE). This study assessed the efficacy and side effects of HCQ in children with proliferative lupus nephritis (LN). This double-blind, randomized, placebo-controlled trial study was conducted on 60 children with proliferative LN classes III and IV treated with steroids and a mycophenolate (MMF) regimen. Patients were categorized into two groups, the HCQ group (n = 30) and the placebo group (n = 30). They were evaluated initially

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"Effect of different antilipidemic agents and diets on mortality." Clinical Governance: An International Journal 11, no. 3 (2006). http://dx.doi.org/10.1108/cgij.2006.24811cae.009.

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HABIB, N. S., та M. A. KHALIL. "ChemInform Abstract: Antilipidemic Agents. Part 3. Synthesis of Some Heterocyclic Derivatives of β-Sitosterol." ChemInform 21, № 44 (1990). http://dx.doi.org/10.1002/chin.199044272.

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Sankoh, Pharm Sheka, Pharm Abdulai Turay, and Eugene BS Conteh. "Evaluation of Antilipidemic and Organ Protective Effects of Polyherbal Formulation (Raxi) in High- Fat Diet and Streptozotocin-Induced Diabetic Rats." International Journal of Innovative Science and Research Technology, July 22, 2025, 1557–64. https://doi.org/10.38124/ijisrt/25jul454.

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Background: Diabetes mellitus, particularly type 2 diabetes, is a multifactorial metabolic disorder often accompanied by dyslipidemia and oxidative stress-related organ damage. While synthetic antidiabetic agents offer glycemic control, their long-term use is associated with adverse effects. Polyherbal formulations present a promising alternative due to their multifaceted therapeutic properties and favorable safety profiles.  Objective: This study aimed to evaluate the antilipidemic, hypoglycemic, and organ-protective effects of a polyherbal formulation, RAXI, in a rat model of type 2 diabete

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Liaqat, Nida, Nazish Jahan, Khalil ur Rahman, Iqra Tahseen, Tauseef Anwar, and Huma Qureshi. "Investigation of phytotherapeutic potential of herbal mixtures and their effects on salbutamol induced cardiotoxicity and hyperlipidemia in rabbits." Botanical Studies 64, no. 1 (2023). http://dx.doi.org/10.1186/s40529-023-00394-9.

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Abstract Background Cardiovascular diseases (CVDs) are the major cause of deaths all over the world. The high level of blood cholesterol and oxidative stress are major risk factors for heart diseases. The phytotherapeutics have attracted attention as potential agents for preventing and treating oxidative stress associated diseases. The objective of present study was to evaluate the synergetic cardio-protective and antilipidemic potential of medicinal plants viz. Coriandrum sativum, Piper nigrum and Cactus grandiflorus. Cardio-protective and anti-lipidemic potential of herbal mixture was evalua

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