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Journal articles on the topic 'Antimalarial plants'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Rizki, Andita Fitri Mutiara, Wihda Aisarul Azmi, Muhaimin Muhaimin, Melva Louisa, I. Made Artika, and Josephine Elizabeth Siregar. "Antimalarial Activity of Mangrove Plants and Possible Mechanisms of Action: A Scoping Review." Molekul 19, no. 1 (2024): 98. http://dx.doi.org/10.20884/1.jm.2024.19.1.9236.

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Malaria is one of life threatening-infectious diseases with high mortality rate in African regions. Malaria is also one of public health problem in most of Southeast Asia (SEA) regions. This disease is caused by a Apicomplexan parasite; Plasmodium sp., which can be transmitted from humans to humans via Anopheles sp. To date, the need of a new antimalarial drug is still high, due to the rapid increase of drug resistance. Natural-derived drug candidates are still being used by researchers to develop new antimalarials. One of the natural resources which could potentially be a source of antimalari

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MODUPE IRETIOLA BUILDERS. "The potency of plant antimalarial." World Journal of Biology Pharmacy and Health Sciences 12, no. 1 (2022): 190–99. http://dx.doi.org/10.30574/wjbphs.2022.12.1.0113.

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Malaria has remained a major cause of morbidity and mortality in all parts of the world. It is associated with high economic burden on the nation, high prevalence of mortality in children, pregnant women and non-immune individuals, thus malaria is a global public health problem. This protozoan infection is mainly characterized by fever, pains, loss of appetite and anaemia, researchers had discovered potent antimalarial drugs mainly from plant sources in order to overcome resistance of antimalarials, vectors, inability to develop malarial vaccines and also toxic effects of conventional antimala

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MODUPE, IRETIOLA BUILDERS. "The potency of plant antimalarial." World Journal of Biology Pharmacy and Health Sciences 12, no. 1 (2022): 190–99. https://doi.org/10.5281/zenodo.7602949.

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Malaria has remained a major cause of morbidity and mortality in all parts of the world. It is associated with high economic burden on the nation, high prevalence of mortality in children, pregnant women and non-immune individuals, thus malaria is a global public health problem. This protozoan infection is mainly characterized by fever, pains, loss of appetite and anaemia, researchers had discovered potent antimalarial drugs mainly from plant sources in order to overcome resistance of antimalarials, vectors, inability to develop malarial vaccines and also toxic effects of conventional antimala

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Triatmoko, Bawon, Dwi Koko Pratoko, Antonius Nugraha Widhi Pratama, Yoshinta Debi Purnomo, Tinton Agung Laksono, and Ari Satia Nugraha. "Preliminary Study on Antimalarial Agent From Indonesian Swietenia Mahagoni and Kibatalia Arborea." Proceedings of the International Conference on Green Technology 10 (December 31, 2019): 13. http://dx.doi.org/10.18860/icgt.v10i0.1113.

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Malaria is a global public health concern due to the increase of resistance to antimalarials, therefore the search for new antimalarials is of importance. This study was conducted to explore the antimalarial activity of Swietenia mahagoni and Kibatalia arborea in the form of crude methanolic extract. The plants were collected from Klaten-Central Java, and Batu-East Java, Indonesia. In vitro antimalarial assay was done against Plasmodium falciparum. Phytochemical studies were done chemically using Dragendorff’s reagent and spectroscopically using the 1H-NMR technique. Results show that the extr

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Krishnaswamy, Savitha. "Potent future antimalarials from Indian indigenous plants: a systematic review." International Journal Of Community Medicine And Public Health 6, no. 12 (2019): 5364. http://dx.doi.org/10.18203/2394-6040.ijcmph20195500.

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Malaria has a global impact due to development of resistance against the frontline anti-malarial drugs which include artemisinin and its derivatives. According to the ancient Indian system of medicine, the Ayurveda, several Indian indigenous plants have been used for treating various ailments. The use of Indian indigenous plants for treatment of malaria is proving to be quite effective and also offers as a cheaper alternative. The purpose of this review is to obtain knowledge about the different Indian indigenous plants that have antimalarial and antiplasmodial biological activities. Literatur

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Omara, Timothy. "Antimalarial Plants Used across Kenyan Communities." Evidence-Based Complementary and Alternative Medicine 2020 (June 12, 2020): 1–31. http://dx.doi.org/10.1155/2020/4538602.

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Malaria is one of the serious health problems in Africa, Asia, and Latin America. Its treatment has been met with chronic failure due to pathogenic resistance to the currently available drugs. This review attempts to compile phytotherapeutical information on antimalarial plants in Kenya based on electronic data. A comprehensive web search was conducted in multidisciplinary databases, and a total of 286 plant species from 75 families, distributed among 192 genera, were retrieved. Globally, about 139 (48.6%) of the species have been investigated for antiplasmodial (18%) or antimalarial activitie

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Gomes, Antonio Rafael Quadros, Heliton Patrick Cordovil Brígido, Valdicley Vieira Vale, Juliana Correa-Barbosa, Sandro Percário, and Maria Fâni Dolabela. "Antimalarial potential of quinones isolated from plants: an integrative review." Research, Society and Development 10, no. 2 (2021): e38210212507. http://dx.doi.org/10.33448/rsd-v10i2.12507.

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Antimalarial treatment is often associated with the resistance developed by Plasmodium which generate ineffective drug treatment. Based on this, the search for therapeutic alternatives is necessary and urgent. This review intends to assess the antimalarial potential of quinones isolated from plants. The search for scientific articles was carried out on the CAPES Journal Portal (PPC), Virtual Health Library (VHL), PUBMED, NCBI and SCIELO, using the following descriptors: quinones and antimalarials. Inclusion criteria were adopted based on studies about quinones isolated from plants and tested a

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TOMCHINSKY, Bernardo, Lin Chau MING, Valdely Ferreira KINUPP, Ari de Freitas HIDALGO, and Francisco Célio Maia CHAVES. "Ethnobotanical study of antimalarial plants in the middle region of the Negro River, Amazonas, Brazil." Acta Amazonica 47, no. 3 (2017): 203–12. http://dx.doi.org/10.1590/1809-4392201701191.

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ABSTRACT The middle Rio Negro region is an interesting place to seek novel antimalarial compounds because of the traditional knowledge of the Amazon population in conjunction with the high biodiversity of the region. The objective of this work was to study the use of antimalarial plants in Barcelos, state of Amazonas, Brazil. Fifty-two local specialists from eight different communities were interviewed over one year. The identified plants were collected with the assistance of local specialists, classified to species level and deposited in herbarium. In total, 55 antimalarial plants were identi

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Phillipson, J. D., and M. J. O'Neill. "Novel antimalarial drugs from plants?" Parasitology Today 2, no. 12 (1986): 355–59. http://dx.doi.org/10.1016/0169-4758(86)90058-x.

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Ihwan, Ihwan, and Sari Hauliah Ahmad Koda. "Antimalarial Herbal Plants in Kupang, Indonesia." Biosaintifika: Journal of Biology & Biology Education 9, no. 1 (2017): 95. http://dx.doi.org/10.15294/biosaintifika.v9i1.5811.

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<p>Malaria is an infectious disease caused by Plasmodium parasite transmitted through female Anopheles mosquito bite. This disease is harmful because Plasmodium is known to be resistant to antimalarial drugs. The emergence of malaria resistance has raised concerns among researchers to look for any alternative antimalarial drugs. There are some plants potentially used as antimalarial drugs that should bewell-documented through scientific research. This study aimed to get to know plant species that has antimalarial activity in Kupang region. Method: This research applied qualitative descri

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Mesa Vanegas, Ana Maria, Silvia Blair та Carlos Peláez. "Inhibición de la formación de β-hematina de especies colombianas de los géneros Piper y Calophyllum como potenciales agentes antimaláricos". Revista de Biología Tropical 66, № 4 (2018): 1412. http://dx.doi.org/10.15517/rbt.v66i4.32121.

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New antimalarial agents from plants are studied as alternatives in the treatment of malaria. The main antimalarials such as chloroquine have several mechanisms of action against parasites, one of which is the inhibition of polymerization of the heme group, a model that has allowed the design of new antimalarial candidates. In this sense the objective of this work was to evaluate extracts of genus Piper and Calophyllum plants on the inhibition capacity of β-hematin. Inhibitory concentrations of β-hematin are reported from 40 extracts of different polarity obtained from the species P. piedecuest

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Ekasari, Wiwied, Anisah Mahardiani, and Nindya Tresiana Putri. "Terpenoids from Euphorbiaceae as a source of antimalarial medicines: A literature review." Pharmacy Education 23, no. 4 (2023): 294–99. http://dx.doi.org/10.46542/pe.2023.234.294299.

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Background: Malaria is an infectious disease caused by the Plasmodium parasite and transmitted by the Anopheles mosquito. Plasmodium falciparum is a parasite that causes the most deaths. Currently, there is resistance to various antimalarial drugs. For this reason, it is necessary to search for new antimalarial agents. Medicinal plants have been shown to play an important role in treating malaria for thousands of years. Some of Euphorbiaceae family plants contains terpenoid compounds, which are compounds with antimalarial activity. Objective: The present review aims to provide an overview of t

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Owolabi, A. A., D. A. Fadare, O. O. Ogbole, and E. O. Ajaiyeoba. "In vivo antimalarial activity of methanol extracts and fractions of Brachystegia eurycoma and Mondia whiteion chloroquine-resistant Plasmodium berghei." Nigerian Journal of Natural Products and Medicine 23 (May 13, 2020): 13–21. http://dx.doi.org/10.4314/njnpm.v23i1.3.

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Malaria remains a major public health problem in the tropics. According to WHO estimates, sub-Saharan Africa continues to carry a disproportionately high share of global malaria burden. Oxidative stress plays significant role in malaria pathogenesis. Recently, there is increasing effort to develop more potent antimalarials from plant source. Brachystegia eurycoma and Mondia whitei are used locally for malaria treatment. Medicinal plants used in therapy quite often possess antioxidant activities as a result of its inherent phytoconstituents. The phytochemical composition of Brachystegia eurycom

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Chaniad, Prapaporn, Tachpon Techarang, Arisara Phuwajaroanpong, Natharinee Horata, Abdi Wira Septama, and Chuchard Punsawad. "Exploring Potential Antimalarial Candidate from Medicinal Plants of Kheaw Hom Remedy." Tropical Medicine and Infectious Disease 7, no. 11 (2022): 368. http://dx.doi.org/10.3390/tropicalmed7110368.

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The Kheaw Hom remedy is a traditional Thai medicine widely used to treat fevers. Some plant ingredients in this remedy have been investigated for their antimicrobial, antiviral, anti-inflammatory, and antioxidant activities. However, there have been no reports on the antimalarial activities of the medicinal plants in this remedy. Therefore, this study focuses on identifying potential antimalarial drug candidates from the medicinal plant ingredients of the Kheaw Hom remedy. Eighteen plants from the Kheaw Hom remedy were extracted using distilled water and ethanol. All extracts were investigated

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Okello, Denis, and Youngmin Kang. "Exploring Antimalarial Herbal Plants across Communities in Uganda Based on Electronic Data." Evidence-Based Complementary and Alternative Medicine 2019 (September 15, 2019): 1–27. http://dx.doi.org/10.1155/2019/3057180.

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Malaria is one of the most rampant diseases today not only in Uganda but also throughout Africa. Hence, it needs very close attention as it can be severe, causing many deaths, especially due to the rising prevalence of pathogenic resistance to current antimalarial drugs. The majority of the Ugandan population relies on traditional herbal medicines for various health issues. Thus, herein, we review various plant resources used to treat malaria across communities in Uganda so as to provide comprehensive and valuable ethnobotanical data about these plants. Approximately 182 plant species from 63

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Valiyaparambil, Shilpa, Muddukrishnaiah Kotakonda, Selvaraj Palanisamy, et al. "Mechanisms of antimalarial activity and drug resistance : Indian antimalarial medicinal plants." Asian Journal of Pharmaceutical and Health Sciences 13, no. 3 (2023): 2872–77. http://dx.doi.org/10.5530/ajphs.2023.13.50.

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Ekasari, Wiwied, Dwi Widya Pratiwi, Zelmira Amanda, Suciati, Aty Widyawaruyanti, and Heny Arwati. "Various Parts of Helianthus annuus Plants as New Sources of Antimalarial Drugs." Evidence-Based Complementary and Alternative Medicine 2019 (November 26, 2019): 1–7. http://dx.doi.org/10.1155/2019/7390385.

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Background. Each part of H. annuus plants is traditionally used as medicinal remedies for several diseases, including malaria. Antimalarial activity of the leaf and the seed has already been observed; however, there is no report about antimalarial activity of the other parts of H. annuus plants. In this study, we assess in vitro and in vivo antimalarial activity of each part of the plants and its mechanism as antimalarial agent against inhibition of heme detoxification. Objective. To investigate the antimalarial activity of various parts of H. annuus. Methods. Various parts of the H. annuus pl

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Ceravolo*, Isabela Penna, Rita de Cassia Cardoso Arcas, and Antoniana Ursine Krettli. "Plants from South America: A Systematic Review of Their Antiplasmodial and Antimalarial Activities Based on Ethnopharmacological Use." Journal of Biomedical Research & Environmental Sciences 5, no. 8 (2024): 921–48. http://dx.doi.org/10.37871/jbres1972.

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Malaria remains one of the most important diseases in the world, being lethal to 610 thousand individuals annually. The widespread resistance of P. falciparum to antimalarials emphasizes the urgent need for new therapies, as treatment remains the primary strategy to control the disease. Although combinations of synthetic drugs are used in treatment, medicinal plants are often utilized in folk medicine as a complement and/or alternative to treat human malaria, especially in poor endemic areas. This systematic review evaluates the antiplasmodial and/or antimalarial activities, as well as the eth

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M, Albuixech-Ginesta, Villarejo-Jimenez A, Velasco-Nuno M, et al. "Elbow Bursitis, Spondylodiscitis and Meningitis Due to Streptococcus agalactiae: A Case Report." Journal of Biomedical Research & Environmental Sciences 5, no. 6 (2024): 515–18. http://dx.doi.org/10.37871/jbres1921.

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Malaria remains one of the most important diseases in the world, being lethal to 610 thousand individuals annually. The widespread resistance of P. falciparum to antimalarials emphasizes the urgent need for new therapies, as treatment remains the primary strategy to control the disease. Although combinations of synthetic drugs are used in treatment, medicinal plants are often utilized in folk medicine as a complement and/or alternative to treat human malaria, especially in poor endemic areas. This systematic review evaluates the antiplasmodial and/or antimalarial activities, as well as the eth

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Valdés, Aymé Fernández-Calienes, Judith Mendiola Martínez, Ramón Scull Lizama, Yamilet Gutiérrez Gaitén, Deyanira Acuña Rodríguez, and Juan Abreu Payrol. "In vitro antimalarial activity and cytotoxicity of some selected cuban medicinal plants." Revista do Instituto de Medicina Tropical de São Paulo 52, no. 4 (2010): 197–201. http://dx.doi.org/10.1590/s0036-46652010000400006.

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Terrestrial plants have been demonstrated to be sources of antimalarial compounds. In Cuba, little is known about antimalarial potentials of plant species used as medicinals. For that reason, we evaluated the antimalarial activity of 14 plant species used in Cuba as antimalarial, antipyretic and/or antiparasitic. Hydroalcoholic extracts were prepared and tested in vitro for the antimalarial activity against Plasmodium falciparum Ghana strain and over human cell line MRC-5 to determine cytotoxicity. Parasite multiplication was determined microscopically by the direct count of Giemsa stained par

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Shooraj, Mahdi, Maryam Al-sadat Mousavi Zade, and Seif Ali Mahdavi. "A Review on Herbal Treatments of Malaria." Tabari Biomedical Student Research Journal 4, no. 4 (2022): 0. http://dx.doi.org/10.32598/tbsrj.v4i4.10520.

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Introduction: Malaria is one of the most common chief health problems all over the world and pharmacotherapy is the common treatment for this disease. Additionally, mankind is blessed with varied range of herbal plants for several ailments which are useful for malaria treatment. The purpose of this investigation is to review the existing studies on the effectiveness of herbal plants in treatment of malaria. Material and Methods: In this study, related articles were reviewed based on keywords and phrases such as antimalarial drugs, herbal plants, treatment in PubMed, Google Scholar, IranDoc and

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Jun, Hojong, Joon-Hee Han, Min Hong, et al. "Ellagic Acid from Geranium thunbergii and Antimalarial Activity of Korean Medicinal Plants." Molecules 30, no. 2 (2025): 359. https://doi.org/10.3390/molecules30020359.

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This study investigates the antimalarial potential of extracts and compounds from various plants used in traditional Korean medicine, in response to the increasing resistance of Plasmodium falciparum to standard treatments such as chloroquine and artemisinin. The antimalarial activity screening was conducted on 151 extracts, identifying the top seven candidates, including Geranium thunbergii (50% ethanol and 100% methanol extract), Reynoutria japonica, Amomum villosum (hot water and 50% ethanol extract), Cinnamomum zeylanicum, and Platycodon grandiflorum. Among these, G. thunbergii was identif

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Daskum, A. M., G. Chessed, M. A. Qadeer, and L. Y. Ling. "Phytochemical screening, Gas Chromatography Mass Spectroscopy (GC-MS) and in vitro antiplasmodial analysis of Senna siamea leaves as antimalarial, Yobe State, Nigeria." Nigerian Journal of Parasitology 41, no. 1 (2020): 60–67. http://dx.doi.org/10.4314/njpar.v41i1.10.

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Poverty and lack of access to health facilities had necessitated the less privileged to depend on herbal remedies to treat a number of diseases including malaria. The successes recorded from the discovery of novel antimalarials from plant sources had paved the way for the search of antimalarial compounds from traditional pharmacopeia. Phytochemical analysis as well as GC-MS analysis of crude leaves extract of Senna siamea was conducted, with a view to identifying compounds with biological activities. Further antimalarial assessment of the crude extracts was also performed in an in vitro assay.

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FRAUSIN, G., R. B. S. LIMA, A. F. HIDALGO, L. C. MING, and A. M. POHLIT. "Plants of the Araceae family for malaria and related diseases: a review." Revista Brasileira de Plantas Medicinais 17, no. 4 (2015): 657–66. http://dx.doi.org/10.1590/1983-084x/14_024.

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ABSTRACTIn the current work we performed a review of the Araceae family species traditionally used to treat malaria and its symptoms. The aim is to reveal the large number of antimalarial Araceae species used worldwide and their great unexplored potential as sources of antimalarial natural products. The SciFinder Scholar, Scielo, PubMed, ScienceDirect and Google books search engines were consulted. Forty-three records of 36 species and 23 genera of Araceae used for malaria and symptoms treatment were found. The neotropical genera Philodendron Schott and Anthurium Schott were the best represent

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Musila, M. F., S. F. Dossaji, J. M. Nguta, C. W. Lukhoba, and J. M. Munyao. "In vivo antimalarial activity, toxicity and phytochemical screening of selected antimalarial plants." Journal of Ethnopharmacology 146, no. 2 (2013): 557–61. http://dx.doi.org/10.1016/j.jep.2013.01.023.

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Otuu, CA, I. C. Ekuma, R. N. N. Obiezue, et al. "Evaluation of Metabolite Compositions and Antimalarial Efficacy of Alstonia boonei (Cheese wood) in Plasmodiun-infected white albino mice (BALB/c)." Bulletins of Natural and Applied Sciences 2, no. 2 (2025): 34–40. https://doi.org/10.5281/zenodo.15505213.

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<strong>Abstract</strong> <strong>Background of the study:</strong> The recent increase in resistance of the malaria parasite has led to the urgent need for new and novel antimalarial molecules with different modes of action to combat the resistance. Plants have in the past proven to be sources of new molecules for drug development against diseases including malaria. <strong>Statement of problem:</strong> The increase in antimalarial drug resistance has greatly affected efforts towards the control and prevention of malaria in recent years. Hence, there is an urgent need for the discovery of ne

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Asnake, Solomon, Tilahun Teklehaymanot, Ariaya Hymete, Berhanu Erko, and Mirutse Giday. "Survey of Medicinal Plants Used to Treat Malaria by Sidama People of Boricha District, Sidama Zone, South Region of Ethiopia." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/9690164.

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In Ethiopia, malaria control has been complicated due to resistance of the parasite to the current drugs. Thus, new drugs are required against drug-resistantPlasmodiumstrains. Historically, many of the present antimalarial drugs were discovered from plants. This study was, therefore, conducted to document antimalarial plants utilized by Sidama people of Boricha District, Sidama Zone, South Region of Ethiopia. An ethnobotanical survey was carried out from September 2011 to February 2012. Data were collected through semistructured interview and field and market observations. Relative frequency o

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Mamede, Lucia, Allison Ledoux, Olivia Jansen, and Michel Frédérich. "Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents." Planta Medica 86, no. 09 (2020): 585–618. http://dx.doi.org/10.1055/a-1148-9000.

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AbstractMalaria is a parasitic disease endemic to tropical and subtropical regions responsible for hundreds of millions of clinical cases and hundreds of thousands of deaths yearly. Its agent, the Plasmodium sp., has a highly variable antigenicity, which accounts for the emergence and spread of resistance to all available treatments. In light of this rising problem, scientists have turned to naturally occurring compounds obtained from plants recurrently used in traditional medicine in endemic areas. Ethnopharmacological approaches seem to be helpful in selecting the most interesting plants for

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Puspaningtyas, Ayik Rosita. "STUDI FITOKIMIA IRVINGIA MALAYANA SEBAGAI ANTIMALARIA DARI HUTAN MERU BETIRI DALAM RANGKA DRUG DISCOVERY." Jurnal Ilmiah Farmasi Farmasyifa 1, no. 2 (2018): 104–18. http://dx.doi.org/10.29313/jiff.v1i2.3340.

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Meru Betiri forest in Jember contains a lot of medicinal plants. Irvingia malayana (Pauh Kijang), which is one of the medicinal plants found, has been proven as an antimalarial. However, phytochemical and antimalarial studies of Irvingia malayana have never been carried out. This study was conducted for an antimalarial Drug Discovery through phytochemical study by isolating the roots, stems, and leaves of Irvingia malayana. From the analysis using FTIR, H-NMR, and GC-MS, it was concluded that the compound in the ethyl acetate extract of Irvingia malayana stem was terpenoids that was included i

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Korsah, Samuel. "In vitro antiplasmodial activity of six plants against chloroquine-sensitive and resistant strains of Plasmodium falciparum." Journal of Pharmacy 5, no. 1 (2025): 46–56. https://doi.org/10.31436/jop.v5i1.319.

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Introduction: The effectiveness of the first-line malaria treatment has been affected by drug resistance and adverse side effects leading to a limited number of treatment options. This calls for the search for alternative antimalarial agents. The study evaluated the in vitro antimalarial activity of six plants frequently used in herbal antimalarial products in Ghana against chloroquine-sensitive strain (3D7) and chloroquine-resistant strain (DD2) of Plasmodium falciparum. Method: Aqueous extracts were prepared from the plants by decoction and freeze-dried. A fluorescence-based SYBR Green assay

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Kibuuka, Rukundo Sande. "The Role of Traditional Medicinal Plants in Managing Malaria and HIV Co-Infection." Research Output Journal of Biological and Applied Science 4, no. 3 (2024): 38–42. http://dx.doi.org/10.59298/rojbas/2024/433842.

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Malaria and HIV co-infection presents a significant public health challenge, particularly in Sub-Saharan Africa, where co-morbidity rates are highest. Conventional therapies, including antiretrovirals and antimalarial drugs, are expensive and often associated with side effects that lead to noncompliance. Traditional medicinal plants offer an affordable and culturally accepted alternative. This review explores various plants used historically in the treatment of both malaria and HIV, focusing on their phytochemical constituents, mechanisms of action, and clinical efficacy. Plants such as Cathar

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Uzor, Philip F. "Alkaloids from Plants with Antimalarial Activity: A Review of Recent Studies." Evidence-Based Complementary and Alternative Medicine 2020 (February 12, 2020): 1–17. http://dx.doi.org/10.1155/2020/8749083.

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Malaria is one of the major health problems in developing countries. The disease kills a large number of people every year and also affects financial status of many countries. Resistance of the plasmodium parasite, the causative agent, to the existing drugs, including chloroquine, mefloquine, and artemisinin based combination therapy (ACT), is a serious global issue in malaria treatment and control. This warrants an urgent quest for novel compounds, particularly from natural sources such as medicinal plants. Alkaloids have over the years been recognized as important phytoconstituents with inte

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Godse, ChhayaS, AshwinikumarA Raut, NutanS Nabar, and JayashreeV Joshi. "Reverse pharmacology for antimalarial plants goes global." Journal of Ayurveda and Integrative Medicine 2, no. 4 (2011): 163. http://dx.doi.org/10.4103/0975-9476.90763.

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Shankar, Rama, BK Sharma, and Sourabh Deb. "Antimalarial plants of northeast India: An overview." Journal of Ayurveda and Integrative Medicine 3, no. 1 (2012): 10. http://dx.doi.org/10.4103/0975-9476.93940.

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Oketch-Rabah, H. A., S. F. Dossaji, and E. K. Mberu. "Antimalarial Activity of Some Kenyan Medicinal Plants." Pharmaceutical Biology 37, no. 5 (1999): 329–34. http://dx.doi.org/10.1076/phbi.37.5.329.6053.

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Gbeassor, M., Y. Kossou, K. Amegbo, C. De Souza, K. Koumaglo, and A. Denke. "Antimalarial effects of eight african medicinal plants." Journal of Ethnopharmacology 25, no. 1 (1989): 115–18. http://dx.doi.org/10.1016/0378-8741(89)90051-2.

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Garavito, G., J. Rincón, L. Arteaga, et al. "Antimalarial activity of some Colombian medicinal plants." Journal of Ethnopharmacology 107, no. 3 (2006): 460–62. http://dx.doi.org/10.1016/j.jep.2006.03.033.

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Kirby, Geoffrey C. "Plants as a Source of Antimalarial Drugs." Tropical Doctor 27, no. 1_suppl (1997): 7–11. http://dx.doi.org/10.1177/00494755970270s105.

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Milliken, William. "Malaria and Antimalarial Plants in Roraima, Brazil." Tropical Doctor 27, no. 1_suppl (1997): 20–25. http://dx.doi.org/10.1177/00494755970270s108.

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One of the numerous problems created by the gold rush which took place in northern Brazil (Roraima State) at the end of the 1980s was a severe epidemic of malaria amongst the indigenous peoples of the region. Worst hit were the Yanomami Indians, who had lived in almost total isolation prior to this event. The problem has been exacerbated by the development of chloroquine-resistant strains of Plasmodium falciparum. In an effort to identify viable alternatives to dependence on western medicine for malaria treatment, a survey was carried out on the local plant species (wild and cultivated) used f

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Bhatnagar, Sunita, and P. Das. "Antimalarial Activity in Tropical Plants: A Review." Journal of Herbs, Spices & Medicinal Plants 13, no. 1 (2007): 103–32. http://dx.doi.org/10.1300/j044v13n01_09.

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Gessler, M. C., M. H. H. Nkunya, L. B. Mwasumbi, M. Heinrich, and M. Tanner. "Screening Tanzanian medicinal plants for antimalarial activity." Acta Tropica 56, no. 1 (1994): 65–77. http://dx.doi.org/10.1016/0001-706x(94)90041-8.

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Achieng M., Nyambura. "Medicinal Plants as a Source of Antimalarial Agents: A Review of Current Research." RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES 5, no. 1 (2025): 38–42. https://doi.org/10.59298/rijbas/2025/513842.

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Malaria remains a significant public health challenge, with millions affected annually and the rapid emergence of drug-resistant Plasmodium species exacerbating the issue. This review examines the historical, ethnobotanical, and contemporary scientific knowledge on the role of medicinal plants in antimalarial therapy. Many plants, such as Artemisia annua and Cinchona species, have yielded potent antimalarial compounds like artemisinin and quinine, respectively. Traditional knowledge continues to inspire modern drug discovery efforts, although much remains unexplored. Advances in in vitro and i

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Hossainey, Muhammad Riadul Haque, Saiful Arefeen Sazed, Maisha Khair Nima, et al. "Investigation of antimalarial activity and cytotoxicity profiling of a Bangladeshi plant Syzygium cymosum." Journal of Infection in Developing Countries 14, no. 08 (2020): 924–28. http://dx.doi.org/10.3855/jidc.12740.

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Introduction: The persistent increase of resistance to existing antimalarials underscores the needs for new drugs. Historically, most of the successful antimalarial are derived from plants. The leaves of the S. cymosum is one of the plant materials used by traditional healers in malaria-endemic areas in Bangladesh for treatment of malaria. Here, we investigated the crude extract and its fractions against chloroquine (CQ)-sensitive 3D7, CQ-resistant Dd2, and artemisinin (ART)-resistant IPC 4912 Mondulkiri strains of Plasmodium falciparum. Methodology: The antimalarial activities were test

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Ngibad, Khoirul. "Efektivitas Kombinasi Ekstrak Etanol Daun Bunga Matahari dan Tanaman Anting-Anting sebagai Antimalaria Secara In Vivo." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 5, no. 1 (2019): 12–19. http://dx.doi.org/10.22487/j24428744.2019.v5.i1.11860.

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Sunflower (Helianthus annuus) and anting-anting (Acalypha indica Linn), can be studied as efficacious malaria medicinal plants for preventing the development of malaria plasmodium resistance. This study aims to determine the effectiveness of the combination of 80% ethanol extract of sunflower leaves and anting-anting as antimalarials. This study included extraction of sunflower leaves and anting-anting plant separately using the maceration method for 24 hours with 80% ethanol. Stirring is aided by a 3 hour shaker and then the obtained extracts were mixed and tested in vivo antimalarial activit

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Applequist, Wendy L., Michel Ratsimbason, Alyse Kuhlman, Stephan Rakotonandrasana, Vincent Rasamison, and David G. I. Kingston. "Antimalarial Use of Malagasy Plants Is Poorly Correlated with Performance in Antimalarial Bioassays." Economic Botany 71, no. 1 (2017): 75–82. http://dx.doi.org/10.1007/s12231-017-9373-3.

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O'Neill, M. J., D. H. Bray, P. Boardman, et al. "Plants as sources of antimalarial drugs: in vitro antimalarial activities of some quassinoids." Antimicrobial Agents and Chemotherapy 30, no. 1 (1986): 101–4. http://dx.doi.org/10.1128/aac.30.1.101.

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Abbas, Jamilah. "In vitro antimalarial activity of Calophyllum bicolor and hemozoin crystals observed by Transmission Electron Microscope (TEM)." MATEC Web of Conferences 154 (2018): 04004. http://dx.doi.org/10.1051/matecconf/201815404004.

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Objective : In continuation of our antimalarial candidate drug discovery program on Indonesia medicinal plants especially from stem bark of Calophyllum bicolor. Metode : We extracted of bioactive crude extract with hexane, acetone and methanol from stem bark of Calophyllum bicolor and evaluated their antimalarial activity by using parasite Plasmodium falciparum in vitro. Results: Methanol fraction showed most active and potent antimalarial activity dose dependent in in vitro experiments with IC50 = 0.52 ppb, and hexane fraction showed moderate antimalarial activity, but dose not dependent, whi

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Gedif, Teferi, and Hahn Heinz-Jürgen. "Treatment of Malaria in Ethiopian Folk Medicine." Tropical Doctor 32, no. 4 (2002): 206–9. http://dx.doi.org/10.1177/004947550203200408.

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Key informant interviews of herbalists were conducted to document the traditional management of malaria in Ethiopia. The perceptions of the cause and symptoms of malaria, the use of plants, their preparation and administration were recorded. Interviews were performed in rural Butajira and Addis Ababa (the main city). The result showed that 33 (75%) of the interviewed healers treat malaria using herbal drugs. Sixteen plants were reported to have been used of which eight were used as a single remedy and the rest as composite remedies with other plants. The ethnopharmacological data generated in

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Rostand, Offoumou M’Baï, Kipré Gueyraud Rolland, Silué Kigbafori Dieudonné, et al. "IN VIVO TOXICITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF TWELVE ANTIMALARIAL PLANTS." Indian Research Journal of Pharmacy and Science 5, no. 1 (2018): 1245–50. http://dx.doi.org/10.21276/irjps.2018.5.1.3.

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Herlina, Tati, Anderson Arnold Aloanis, Dikdik Kurnia, Desi Harneti, Rani Maharani, and Unang Supratman. "Prenylated Isoflavanones from the Stem Bark of Erythrina poeppigiana (Leguminosae) and its Antimalarial Properties." Natural Product Communications 12, no. 8 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200825.

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During the course of our continuous search for novel antimalarial compounds derived from the Indonesian Erythrina plants, the methanol extract of the stem bark of Erythrina poeppigiana demonstrated significant antimalarial activity against Plasmodium falciparum parasites, in vitro. Bioassay-guided fractionation of the ethyl acetate extract resulted in the isolation of three known platyisoflavanone (1), erypogein D (2), and sophoraisoflavanone A (3). Compounds 1–3 showed strong antimalarial activity against 3D7 strain of P. falciparum with IC50 values of 0.52, 0.36, and 3.65μM, respectively. Th

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