Academic literature on the topic 'Antimalarials of natural origin'

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Journal articles on the topic "Antimalarials of natural origin"

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Gademann, Karl, and Joanna Kobylinska. "Antimalarial natural products of marine and freshwater origin." Chemical Record 9, no. 3 (2009): 187–98. http://dx.doi.org/10.1002/tcr.200900001.

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Straschil, Ursula, Kathrin Witmer, Michael J. Delves, Stephen D. Marks, and Jake Baum. "Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials." Archives of Disease in Childhood 104, no. 12 (2019): 1138–42. http://dx.doi.org/10.1136/archdischild-2019-317590.

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ObjectiveThe global impact of artemisinin-based combination therapies on malaria-associated mortality and their origins in ancient Chinese medicine has heightened interest in the natural discovery of future antimalarials.MethodsA double-blind study to identify potential ingredients with antimalarial activity from traditional remedies with reported antipyretic properties. Recipes of clear broths, passed down by tradition in families of diverse ethnic origin, were sourced by school children. Broths were then tested for their ability to arrest malaria parasite asexual growth or sexual stage devel
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Silva, Ana Teresa, Clara M. Bento, Ana C. Pena, et al. "Cinnamic Acid Conjugates in the Rescuing and Repurposing of Classical Antimalarial Drugs." Molecules 25, no. 1 (2019): 66. http://dx.doi.org/10.3390/molecules25010066.

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Cinnamic acids are compounds of natural origin that can be found in many different parts of a wide panoply of plants, where they play the most diverse biological roles, often in a conjugated form. For a long time, this has been driving Medicinal Chemists towards the investigation of the therapeutic potential of natural, semi-synthetic, or fully synthetic cinnamic acid conjugates. These efforts have been steadily disclosing promising drug leads, but a wide chemical space remains that deserves to be further explored. Amongst different reported approaches, the combination or conjugation of cinnam
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Bilia, Anna Rita. "Non-nitrogenous Plant-derived Constituents with Antiplasmodial Activity." Natural Product Communications 1, no. 12 (2006): 1934578X0600101. http://dx.doi.org/10.1177/1934578x0600101218.

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The paper is a compilation of the studies reported in the literature concerning non-nitrogenous natural constituents that have shown antiplasmodial activity and aims to provide a basis for further in vivo studies as well as for clinical trials to develop new antimalarial agents. Due to the increasingly unsatisfactory outcomes for N-heterocyclic drugs, coupled with the rising incidence of the deadly falciparum malaria, the advent of non-nitrogenous lead compounds is timely, signaling a new era of antimalarial chemotherapy. Currently a few non-nitrogenous molecules are used in therapy, but many
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Costa da Silva, Milena, Michele Dayane Rodrigues Leite, Suelem Sonaly Lima Oliveira, Thiago Bizerra Fideles, and Marcus Vinícius Lia Fook. "Morphological Evaluation of Chitosan/Curcumin Beads and Powder: Effect of the Methanol as a Solvent." Materials Science Forum 869 (August 2016): 854–58. http://dx.doi.org/10.4028/www.scientific.net/msf.869.854.

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Curcumin is a polyphenolic component of Curcuma longa, highlighting in the literature by presenting medicinal properties such as: antioxidant, anti-inflammatory, antibacterial, antiparasitic, antimalarial and anticancer activities. From this, it has been used together with curcumin, chitosan, a biodegradable polymer of natural origin, in order to encapsulate curcumin from a polymer system. Thus, this study aimed to evaluate the morphological behavior of beads and powder chitosan/curcumin, by the Optical Microscopy (OM) technique in the presence of the solvent (methanol). From the pictures, it
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Opsenica, Igor, Dejan Opsenica, Milka Jadranin, et al. "On peroxide antimalarials." Journal of the Serbian Chemical Society 72, no. 12 (2007): 1181–90. http://dx.doi.org/10.2298/jsc0712181o.

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Several dicyclohexylidene tetraoxanes were prepared in order to gain a further insight into structure-activity relationship of this kind of antimalarials. The tetraoxanes 2-5, obtained as a cis/trans mixture, showed pronounced antimalarial activity against Plasmodium falciparum chloroquine susceptible D6, chloroquine resistant W2 and multidrug-resistant TM91C235 (Thailand) strains. They have better than or similar activity to the corresponding desmethyl dicyclohexylidene derivatives. Two chimeric endoperoxides with superior antimalarial activity to the natural product ascaridole were also synt
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Lawal, Bashir, Oluwatosin Shittu, Adamu Kabiru, et al. "Potential antimalarials from African natural products: a review." Journal of Intercultural Ethnopharmacology 4, no. 4 (2015): 318. http://dx.doi.org/10.5455/jice.20150928102856.

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Fatima, Anish. "Screening of Antibacterial Activity of Azadirachta Indica (Neem) by Using Leaf Extract against Escherichia Coli and Bacillus Subtilis." International Journal for Research in Applied Science and Engineering Technology 9, no. VII (2021): 1602–5. http://dx.doi.org/10.22214/ijraset.2021.36641.

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Azadirachta Indica (Neem) is the member of the Meliaceae family. It is rich source of Antibacterial properties and Antioxidants. They have consist 65 biochemically active compounds. In ancient time plant and plant product are used for medicine. Neem (Azadirachta indica) is the most useful and traditional medicine used in India. They are also used in cosmetics and beauty aid. The demand of neem products are increasing day by day. In agricultural sector is now becoming a major consumer of the neem products. They also have use agricultural, Pesticides made from neem are product if natural plant o
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Tehzeeb T, Tehzeeb, and Dhanabalan Dhanabalan D. "A Review on Natural Sources of Antimalarials: Fungi and Plants." International Journal of Pharmaceutical Investigation 10, no. 4 (2020): 417–22. http://dx.doi.org/10.5530/ijpi.2020.4.74.

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Mamede, Lucia, Allison Ledoux, Olivia Jansen, and Michel Frédérich. "Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents." Planta Medica 86, no. 09 (2020): 585–618. http://dx.doi.org/10.1055/a-1148-9000.

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AbstractMalaria is a parasitic disease endemic to tropical and subtropical regions responsible for hundreds of millions of clinical cases and hundreds of thousands of deaths yearly. Its agent, the Plasmodium sp., has a highly variable antigenicity, which accounts for the emergence and spread of resistance to all available treatments. In light of this rising problem, scientists have turned to naturally occurring compounds obtained from plants recurrently used in traditional medicine in endemic areas. Ethnopharmacological approaches seem to be helpful in selecting the most interesting plants for
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Dissertations / Theses on the topic "Antimalarials of natural origin"

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Alvarado, Stephenie M. "Identification of novel antimalarials from marine natural products for lead discovery." Master's thesis, University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4591.

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An estimated 500 million cases of malaria occur each year. The increasing prevalence of drug resistant strains of Plasmodium in most malaria endemic areas has significantly reduced the efficacy of current antimalarial drugs for prophylaxis and treatment of this disease. Therefore, discovery of new, inexpensive, and effective drugs are urgently needed to combat this disease. Marine biodiversity is an enormous source of novel chemical entities and has been barely investigated for antimalarial drug discovery. In an effort to discover novel therapeutics for malaria, we studied the antimalarial act
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Munedzimwe, Tatenda Carol. "The isolation, quantification and synthetic modification of antiplasmodial natural products from sargassum heterophyllum." Thesis, Rhodes University, 2012. http://hdl.handle.net/10962/d1018252.

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Malaria is one of the most deadly parasitic diseases known to man. Although the number of malaria cases reported each year is decreasing, this disease continues to pose health and economic problems mainly in developing countries. Significant progress has been made in the fight against this disease. This includes the discovery and development of potent antimalarial agents. However, the development of resistance to most of these potent antimalarials has made the development of new antiplasmodial agents of paramount importance. Several promising antiplasmodial agents have been found from the mari
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Ziegler, Hanne Lindvig. "Antiplasmodial activity of natural products : effect of incorporation into erythrocyte membrane /." Cph. : Royal Danish School of Pharmacy, Department of Medicinal Chemistry, 2002. http://www.dfh.dk/phd/defences/hanneziegler.htm.

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Egieyeh, Samuel Ayodele. "Computational strategies to identify, prioritize and design potential antimalarial agents from natural products." University of the Western Cape, 2015. http://hdl.handle.net/11394/5058.

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Philosophiae Doctor - PhD<br>Introduction: There is an exigent need to develop novel antimalarial drugs in view of the mounting disease burden and emergent resistance to the presently used drugs against the malarial parasites. A large amount of natural products, especially those used in ethnomedicine for malaria, have shown varying in-vitro antiplasmodial activities. Facilitating antimalarial drug development from this wealth of natural products is an imperative and laudable mission to pursue. However, the limited resources, high cost, low prospect and the high cost of failure during preclinic
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Wangchuk, Phurpa. "Bioactive alkaloids from medicinal plants of Bhutan." Department of Chemistry - Faculty of Science, 2004. http://ro.uow.edu.au/theses/315.

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Natural products had been indispensably used by many cultures and traditions in folklore medicines for thousands of years. These traditional medicines cater to about 85% of the world population for their primary health care needs. Natural products have been intensively explored also for their bioactive pharmacophores by modern pharmaceutical companies. In fact they are the skeletal framework of about 60% of the modern drugs that are available today. Of these, about 80% of antibacterial drugs and 90% of antimalarial drugs are natural derivatives. One of the interesting secondary metabolite grou
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Shirley, Neil John. "Synthesis of compounds of natural and unnatural origin by intramolecular alkylations." Title page, contents and summary only, 1987. http://web4.library.adelaide.edu.au/theses/09PH/09phs558.pdf.

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Ringbom, Therese. "Bioassay Development for Identification of Cyclooxygenase-2 Inhibitors of Natural Origin." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5276-0/.

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Felth, Jenny. "Studies of Cytotoxic Compounds of Natural Origin and their Mechanisms of Action." Doctoral thesis, Uppsala universitet, Avdelningen för farmakognosi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-148114.

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Cancer incidence is increasing and novel anticancer drugs with new mechanisms of action are essential for future chemotherapeutic treatment. Natural products have historically played an important role in the development of anti-cancer drugs and have potential to do so also in the future. In this thesis two classes of natural products are identified as possible drug lead candidates, and the mechanisms of their action are elucidated. Initially, in a screening of a compound library for cytotoxic effects in colon cancer cells, natural products with potent activity were identified. Based on their p
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Sowder, Jonathan T. "The origin and fate of arsenic in coalbed natural gas produced water ponds." Laramie, Wyo. : University of Wyoming, 2009. http://proquest.umi.com/pqdweb?did=1935323111&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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Key, Rebecca E. "Progress toward the synthesis of a family of antimalarial diterpenes: potential utilization of Co-salen-catalyzed hydrolytic kinetic resolution (HKR) to form chiral intermediates in the metabolites of Callophycus serratus." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53976.

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Callophycolide A is a meroditerpene isolated from Callophycus serratus, a Fijian red macroalgae. Callophycolide A has been shown to inhibit bacterial growth, and it exhibits moderate cytotoxicity against multiple human cancer cell lines. Most importantly, it exhibits moderate activity against Plasmodium falciparum, the dead- liest malaria-causing parasite to humans. Due to its antimalarial action and the need for antimalarial drugs on the pharmaceutical market, efforts toward a modular approach to the total synthesis of callophycolide A are presented that incorporate inexpensive, commercially
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Books on the topic "Antimalarials of natural origin"

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Opender, Koul, ed. Insecticides of natural origin. Harwood Academic, 1997.

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Jin, He. The origin of natural structure. AuthorHouse, 2009.

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Flies: Their origin, natural history, tying ... Nick Lyons Books, 1988.

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Darwin, Charles. The origin of species. Bridge Logos Foundation, 2009.

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The origin then and now: An interpretive guide to The origin of species. Princeton University Press, 2010.

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Darwin, Charles. The origin of species, 1876. New York University Press, 1988.

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Alexandra, Maryanski, ed. On the origin of societies: By natural selection. Paradigm Publishers, 2008.

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Samuelsson, Gunnar. Drugs of natural origin: A textbook of pharmacology. Swedish Pharmaceutical Press, 1992.

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Samuelsson, Gunnar. Drugs of natural origin: A textbook of pharmacognosy. 4th ed. Apotekarsocieteten, 1999.

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Darwin, Charles. The origin of species. Norton, 2002.

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Book chapters on the topic "Antimalarials of natural origin"

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Ismail, Fyaz M. D. "Nature's Armamentarium against Malaria: Antimalarials and Their Semisynthetic Derivatives." In Nutraceuticals and Natural Product Derivatives. John Wiley & Sons, Inc., 2018. http://dx.doi.org/10.1002/9781119436713.ch13.

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Larkum, Anthony W. D. "The “Origin of Species”." In A Natural Calling. Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-1-4020-9233-6_6.

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Croteau, Rodney, and Frank Karp. "Origin of Natural Odorants." In Perfumes. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-3826-0_4.

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Dembitsky, Valery M., Alexander O. Terent’ev, and Dmitri O. Levitsky. "Aziridine Alkaloids: Origin, Chemistry and Activity." In Natural Products. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-22144-6_93.

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Velde, Bruce, and Isabelle C. Druc. "Origin of Clay Resources." In Natural Science in Archaeology. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-59905-7_4.

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Kanlayavattanakul, Mayuree, and Nattaya Lourith. "Natural Polysaccharides for Skin Care." In Polysaccharides of Microbial Origin. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-35734-4_46-1.

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Christen, Philippe, Stefan Bieri, and Strahil Berkov. "Methods of Analysis: Tropane Alkaloids from Plant Origin." In Natural Products. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-22144-6_35.

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Chaijan, Manat, and Worawan Panpipat. "Mechanism of Oxidation in Foods of Animal Origin." In Natural Antioxidants. CRC Press, 2016. http://dx.doi.org/10.1201/9781315365916-2.

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Capasso, Francesco, and Timothy S. Gaginella. "Natural Laxatives of Mineral Origin." In Laxatives. Springer Milan, 1997. http://dx.doi.org/10.1007/978-88-470-2227-0_6.

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Heath, Henry B., and Gary Reineccius. "Flavoring Materials of Natural Origin." In Flavor Chemistry and Technology. Macmillan Education UK, 1986. http://dx.doi.org/10.1007/978-1-349-09350-2_6.

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Conference papers on the topic "Antimalarials of natural origin"

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Zubova, E. V., and A. S. Novosѐlov. "Comparative characteristics of spruce young artificial and natural origin." In Наука России: Цели и задачи. LJournal, 2019. http://dx.doi.org/10.18411/sr-10-04-2019-49.

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"The Origin of Universal Power Law of Natural Images." In 2017 6th International Conference on Advanced Materials and Computer Science. Clausius Scientific Press Inc., 2017. http://dx.doi.org/10.23977/icamcs.2017.1019.

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Kotarba, Maciej. "Origin of natural gas in the polish outer Carpathians." In International Conference and Exhibition, Barcelona, Spain, 3-6 April 2016. Society of Exploration Geophysicists and American Association of Petroleum Geologists, 2016. http://dx.doi.org/10.1190/ice2016-6435151.1.

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Gyulkhandanyan, Grigor V., Robert K. Ghazaryan, Marina H. Paronyan, Ghukas I. Ulikhanyan, Aram G. Gyulkhandanyan, and Lida A. Sahakyan. "Antimicrobial activity of new porphyrins of synthetic and natural origin." In SPIE BiOS, edited by Michael R. Hamblin, Juanita Anders, and James D. Carroll. SPIE, 2012. http://dx.doi.org/10.1117/12.908634.

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Doughman, Jad, Wael Khreich, Maya El Gharib, Maha Wiss, and Zahraa Berjawi. "Gender Bias in Text: Origin, Taxonomy, and Implications." In Proceedings of the 3rd Workshop on Gender Bias in Natural Language Processing. Association for Computational Linguistics, 2021. http://dx.doi.org/10.18653/v1/2021.gebnlp-1.5.

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Klasik, Marta. "CHARACTERIZATION AND UTILIZATION POTENTIALS OF CARDBOARD AND TEXTILES OF NATURAL ORIGIN." In 15th International Multidisciplinary Scientific GeoConference SGEM2015. Stef92 Technology, 2011. http://dx.doi.org/10.5593/sgem2015/b51/s20.015.

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Nguyen, Minh, Gia H. Ngo, and Nancy Chen. "Multimodal neural pronunciation modeling for spoken languages with logographic origin." In Proceedings of the 2018 Conference on Empirical Methods in Natural Language Processing. Association for Computational Linguistics, 2018. http://dx.doi.org/10.18653/v1/d18-1320.

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Nassar, Marawan Hassan, Ivar Nijenhuis, Tharwat Adbel Fattah, and Alaa Ramadan. "Occurrence, Character ,Origin Of Natural Gases In Deepwater Nile Delta Area - Egypt." In North Africa Technical Conference and Exhibition. Society of Petroleum Engineers, 2012. http://dx.doi.org/10.2118/152891-ms.

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Freitas, Maria do Carmo, Adriano M. G. Pacheco, Gürdal Tuncel, Anselmo Salles Paschoa, and Friedrich Steinhäusler. "Molybdenum and Uranium from Remote Continental Origin at Pico Summit, Pico Island, Azores, Portugal." In THE NATURAL RADIATION ENVIRONMENT: 8th International Symposium (NRE VIII). AIP, 2008. http://dx.doi.org/10.1063/1.2991216.

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Suresh, Gopika, Georg Heygster, Gerhard Bohrmann, Christian Melsheimer, and Jan-Hendrik Korber. "An automatic detection system for natural oil seep origin estimation in SAR images." In IGARSS 2013 - 2013 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2013. http://dx.doi.org/10.1109/igarss.2013.6723600.

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Reports on the topic "Antimalarials of natural origin"

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Seewald, Jeffrey, S. Laboratory Constraints on the Stability of Petroleum at Elevated Temperatures: Implications for the Origin of Natural Gas. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1008348.

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Millings, M. R. Sampling and Analysis Plan for Investigating the Origin of Natural 226Ra, 228Ra, and 238U in South Carolina Coastal Plain Groundwater. Office of Scientific and Technical Information (OSTI), 2003. http://dx.doi.org/10.2172/809739.

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Ayala-García, Jhorland, Sandy Dall'erba, and William C. Ridley. Externalities of extreme natural disasters on local tax capacity. Banco de la República de Colombia, 2021. http://dx.doi.org/10.32468/dtseru.299.

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This paper studies the impact of extreme weather events on the local tax revenue across Colombian municipalities. We follow a two-step approach to evaluate to what extent a municipality’s tax revenue depends on natural disasters taking place both locally and in its trade partners. In the first step, we estimate a gravity model of bilateral trade and construct a trade flow matrix allowing us to measure the strength of the economic relationships between cities. To do so, we build a novel dataset describing the inter-city trade flows for road transported goods in Colombia for the period 2015–2019
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Annual report of the origin of natural gas liquids production form EIA-64A. Office of Scientific and Technical Information (OSTI), 1995. http://dx.doi.org/10.2172/196522.

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Natural Reproductive Success and Demographic Effects of Hatchery-Origin Steelhead in Abernathy Creek, Washington : Annual Report 2008. Office of Scientific and Technical Information (OSTI), 2008. http://dx.doi.org/10.2172/961809.

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