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Dissertations / Theses on the topic 'Antimicrobial activity. Etc'

Author: Grafiati

Published: 7 June 2025

Last updated: 17 July 2025

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1

Kim, Yun Mi. "Structure-antimicrobial activity relationship for a new class of antimicrobials, silanols, in comparison to alcohols and phenols." [Gainesville, Fla.] : University of Florida, 2006. http://purl.fcla.edu/fcla/etd/UFE0015405.

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2

Lentsoane, Robert. "Antimicrobial activity of Melianthus villosus." Diss., Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-05232005-102711/.

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3

Muppalla, Kirankirti. "Functionalization of Resorcinarenes and Study of Antimicrobial Activity." Scholar Commons, 2001. http://scholarcommons.usf.edu/etd/3824.

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Cavitands are very important class of compounds in supramolecular chemistry. These molecules contain rigid enforced cavity,and have attracted considerable attention in supramolecular chemistry as building blocks for the construction of carcerands, hemicarcerands, and other host guests complexes. Nearly 40 years ago, Niederl and Vogel laid foundation for the study of such type of condensation reactions. In our laboratory we are involved in synthesis of resorcinarenes with readily available substrates such as resorcinol and aldehydes to form a cyclic tetramer. Herein, I present detailed studies

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4

Liu, Bin. "Partial Characterization of the Antimicrobial Activity of CCL28." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/2967.

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This research focuses on the antimicrobial activity of the mouse chemokine CCL28. In addition to their well characterized chemotactic activity, many chemokines have been shown to be antimicrobial in vitro, including the mucosally expressed chemokine CCL28. I have investigated the primary sequence features required for antimicrobial activity, salt sensitive nature of killing/binding mechanism, and in vivo microbial interactions of CCL28. Through the use of protein mutation and expression techniques, I have shown that the holoprotein (108 amino acids) is necessary for full antimicrobial activity

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5

Onyenobi, Ebuka Isaiah. "Enzyme Activity and Antimicrobial Screening of Ambrosiella grosmanniae." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1626139065293068.

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6

Franzman, Michael Ryan. "Targeted antimicrobial activity of SMAP28 conjugated to IgG antibody." Thesis, University of Iowa, 2007. http://ir.uiowa.edu/etd/140.

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7

Markopoulos, Marjorie M. "Antimicrobial Activity of Fractionated Borohydride-Capped and Electrochemical Colloidal Silver." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright1515096508634157.

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8

Miller, Andrew B. "Antimicrobial and Anticancer Activity of Essential Oils from Guatemalan Medicinal Plants." BYU ScholarsArchive, 2010. https://scholarsarchive.byu.edu/etd/2411.

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Guatemalan medicinal plants were collected and screened for the presence of essential oils using steam distillation. Oil was found in 63 species from 24 families and was tested in tube dilution assays for activity against Escherichia coli, Staphylococcus aureus, Streptococcus mutans, Lactobacillus acidophilus and Candida albicans. Several essential oils were highly active with 20 instances of oils inhibiting the microbes at an MIC of 0.31 µl/ml. Oils were also tested against cancerous and established cell lines using a 15% (v/v) agar-media which was developed to improve essential oil solubilit

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9

Mohammadihashemi, Marjan. "Antibacterial and Antifungal Activity of Ceragenins, Mimics of Endogenous Antimicrobial Peptides." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/7411.

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The continuous emergence of drug-resistance pathogens is a global concern. As a result, substantial effort is being expended to develop new therapeutics and mechanisms for controlling microbial growth to avoid entering a "post-antibiotic" era in which commonly used antibiotics are no longer effective in treating infections. In this work, we investigate the efficacy and application of ceragenins as non-peptide mimics of antimicrobial peptides (AMPs). First, this work examines the susceptibility of drug-resistant Gram-negative bacteria. The susceptibility of colistin-resistant clinical isolates

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10

Barber, Megan Marie. "2,4-Disubstituted Quinazolines with Antileishmanial or Antibacterial Activity." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5840.

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Herein 47 2,4-disubstituted quinazolines were synthesized and tested against Leishmania donovani intracellular amastigotes. A structure-activity relationship was conducted and lead to the identification of quinazolines with EC50s in the single digit and high nanomolar range with favorable antileishmanial selectivity indexes. Quinazoline 2.6 and 2.31 underwent in vivo efficacy studies in murine models of visceral leishmaniasis, reducing liver parasitemia by 12 % and 24 %, respectively, when given by the intraperitoneal route at 15 mg/kg/day x 5 days. The antileishmanial efficacy and easy of syn

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11

Berkebile, Abigail Rae. "Airway surface liquid antiviral activity in cystic fibrosis." Thesis, University of Iowa, 2015. https://ir.uiowa.edu/etd/2045.

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Cystic fibrosis (CF) is a lethal genetic disease that affects 30,000 people in the United States alone. While the disease affects organs throughout the body, it is the lung disease that is the primary cause of morbidity and mortality for people with the disease. CF lung disease is characterized by thick and sticky mucus that obstructs the airways, acute and chronic bacterial infections, and chronic inflammation and remodeling. Thanks to the creation of the CF pig, it is now possible to study the manifestations of CF lung disease at birth. The CF pig develops spontaneous lung disease, similar t

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12

Mutambuze, Jean Wilson. "In Vitro Antimicrobial Activity of BTZ043 and PNU-100480 Against Mycobacterium ulcerans." Kent State University Honors College / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1399313048.

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13

Dallon, Emma Kay. "Exploration of Antimicrobial Activity in Natural Peptides and High-Throughput Discovery of Synthetic Peptides." BYU ScholarsArchive, 2018. https://scholarsarchive.byu.edu/etd/7468.

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Despite many medical advances, antibiotic resistant bacteria increasingly plague the modern world, necessitating discovery of new antibiotics. One area of nature that can provide inspiration for antibiotics is antimicrobial peptides. Many of these peptides exist in nature, with some classes that have not been studied or characterized well. One such class is the defensin-like peptides generated by the plant Medicago truncatula as part of their symbiotic relationship with Sinorhizobium meliloti. Nodule-specific Cysteine Rich (NCR) peptides are defined by the presence of multiple cysteines, and r

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14

Naidoo, Vinasan. "Screening of four plants commonly used in ethnoveterinary medicine for antimicrobial, antiprotozoal and anti-oxidant activity." Diss., University of Pretoria, 2004. http://upetd.up.ac.za/thesis/available/etd-03082005-091015/.

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15

Grimmett, Paul E. "Antimicrobial and spermicidal activity of hydrogen peroxide and nonoxynol-9 based gel preparations." Huntington, WV : [Marshall University Libraries], 2004. http://www.marshall.edu/etd/descript.asp?ref=438.

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16

Kascatan, Nebioglu Aysegul. "N-HETEROCYCLIC CARBENE SILVER(I) COMPLEXES FROM XANTHINES AND THEIR ANTIMICROBIAL APPLICATIONS." University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1176579309.

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17

Wang, Chenbo. "Evaluation of the antimicrobial activity of a bifidobacteria mix against Escherichia coli 0157:H7 under aerobic conditions." Master's thesis, Mississippi State : Mississippi State University, 2006. http://library.msstate.edu/etd/show.asp?etd=etd-04112006-164012.

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18

Peck, M. Thabit. "The antimicrobial activity of four herbal based toothpastes against specific primary plaque colonizers." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7713_1264025047.

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<p>Aim: To determine whether there was any significant difference in the antimicrobial activity of 4 herbal toothpastes against cultures of 3 primary plaque colonizers (Streptococcus mutans, Streptococcus sanguinis and a non-specific &alpha<br>-heamolytic streptococcus).</p>

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19

Samdumu, Faga B. "Characterization of antimicrobial compounds from Combretum paniculatum, a plant with proven anti-HIV replication activity." Electronic thesis, 2007. http://upetd.up.ac.za/thesis/available/etd-08032007-173831/.

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20

Mathekga, Abbey Danny Matome. "Antimicrobial activity of Helichrysum species and the isolation of a new phloroglucinol from Helichrysum caespititium." Diss., Pretoria : [s.n.], 2001. http://upetd.up.ac.za/thesis/available/etd-04012003-141811.

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21

WANG, CHENBO. "EVALUATION OF THE ANTIMICROBIAL ACTIVITY OF A BIFIDOBACTERIA MIX AGAINST ESCHERICHIA COLI O157:H7 UNDER AEROBIC CONDITIONS." MSSTATE, 2006. http://sun.library.msstate.edu/ETD-db/theses/available/etd-04112006-164012/.

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A bifidobacteria mix (nine strains) was evaluated for its effect on the growth and survival of Escherichia coli O157:H7 (ATCC 43890) in 11% NFDM and MRS broth under the optimum growth conditions for E. coli O157:H7 growth (37¡ãC, aerobic). Preliminary experiments were conducted to obtain the growth curves of the 9 strains of bifidobacteria and E. coli O157:H7 and confirm the inhibitory effect of acidity on E. coli O157:H7 (pH of media adjusted to 3.8). Acid-adapted E. coli O157:H7 showed no difference in resistance toward bifidobacteria (P>0.05) when compared to the non-acid adapted one. Esche

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22

Subedi, Yagya P. "Cost-Effective Synthesis, Bioactivity and Cellular Uptake Study of Aminoglycosides with Antimicrobial and Connexin Hemichannel Inhibitory Activity." DigitalCommons@USU, 2019. https://digitalcommons.usu.edu/etd/7699.

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Amphiphilic kanamycin is one of the promising class of compounds for the treatment of fungal infections in plants and animal. Factor that lead to the restricting of compounds for commercialization includes, the higher cost of production and poor stability of the compound. However, the new lead, identified from the synthesis and biological testing, can be synthesized on a large scale with a cost comparable to commercial antifungals. The newly reported lead is stable at the acidic and basic conditions. Additionally, this compound has an excellent activity towards Candida auris, a multidrug-resis

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23

Wright, Brian D. "Synthesis, Characterization, and Biological Activity of Silver Carbene Complexes and Their Precursors." University of Akron / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=akron1353423024.

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24

Shrestha, Jaya P. "Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents." DigitalCommons@USU, 2016. https://digitalcommons.usu.edu/etd/4925.

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Synthesizing bioactive small molecules by structural modification of 1,4-naphthoquinone was the primary goal of this research. Several bioactive compounds with anticancer, antifungal, and antibacterial activities were synthesized. All the synthetic protocols were optimized in such ways that do not require cumbersome purification. First, a new protocol for the synthesis of NQM111 was developed. NQM111 is a highly potent anticancer agent developed in our laboratory, but the old protocol does not provide enough quantity for in vivo study. Therefore, a new safe and improved method was developed wh

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25

Lee, Seung-Min. "Characterization of Lactose Fatty Acid Esters for their Microbial Growth Inhibitory Activity and Emulsification Properties." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/7030.

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Sugar esters, substances made from bonding fatty acid tails to a sugar head, can play a number of key roles in food systems from antimicrobial agents to emulsifiers. These unique and very useful properties result from their water-loving and water-avoiding ends. Lactose, a sugar found in milk, based esters are important, as they are environmentally friendly and inexpensive, however, they are not very well understood. I created four different types of lactose esters: lactose monooctanoate (LMO), lactose monodecanoate (LMD), lactose monolaurate (LML) and lactose monomyristate (LMM), and then comp

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26

Van, Horn Kurt Steven. "Anti-parasitic and anti-bacterial agents: Studies on 1,4-dihydropyridines and 2,4-diaminoquinazolines." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4784.

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Thirty-three 1,4-dihydropyridine diastereomeric pairs were synthesized and the structure-activity relationship studied in a Plasmodium falciparum in vitro model. Twenty-nine of these derivatives contained a 6-position oxygen, with 2.31, 2.32, 2.52 and 2.53 having single and double digit nanomolar activities. This SAR study revealed some insightful information about the 1,4-dihydropyridine substitution pattern. Substitution at the 7-position other than 3,4-dimethoxy severely reduced the activity. 4-phenyl substitution with 2- or 4- halo or methyl formed active compounds while substitution at th

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27

Chen, Mei Xin. "Formulation of Topical Products with Antiviral and Antibacterial Activity." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1417977817.

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28

Barreto, Michael. "Antimicrobial activity of macroalgae from Kwazulu-Natal, South Africa, and the isolation of a bioactive compound from Osmundaria serrata (Rhodophyta)." Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-09052005-095635/.

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29

Anyaogu, Kelechi Chigboo. "Stabilized Metal Nanoparticle-Polymer Composites: Preparation, Characterization and Potential Applications." Bowling Green State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1222126708.

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30

Arnett, Eusondia A. "Neutrophil products inhibit LLO secretion and activity, and Listeria monocytogenes intracellular growth." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1374064718.

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31

Nelson, Tasha K. "A New All-Natural Wound Treatment Gel Shows Strong Inhibitory Activity Against Staphylococcus aureus and Other Wound Pathogens." Digital Commons @ East Tennessee State University, 2021. https://dc.etsu.edu/etd/3911.

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Skin related injuries are some of the most dangerous forms of wounds. In addition to treating the wound itself, health care providers must be cautious of microbial infections. In this study, we evaluate a novel all-natural antimicrobial gel compound (AMG) designed to kill planktonic bacteria, penetrate bacterial biofilms, and accelerate wound healing. In -vitro experiments demonstrate that AMG is effective in inhibiting planktonic growth and biofilm development of eight common pathogens. LIVE/DEAD staining and confocal microscopy reveal that planktonic growth and three-dimensional structure of

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32

Bello, Rafiat Ajoke. "Venom Peptides Lasioglossin II and Mastoparan B as Escherichia coli ATP synthase Inhibitors." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etd/3112.

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The inhibitory effects on Escherichia coli ATPase activity by two venom peptides, lasioglossin II and mastoparan B. Membrane bound F1FO ATP synthase was isolated from E. coli strain pBWU13.4/DK8 and treated with varied concentrations of lasioglossin II and mastoparan B. Lasioglossin II caused very low inhibition of ATPase activity, but the inhibition profile of mastoparan B was suggestive of an interesting biological effect. A relatively shorter total length, a smaller net positive charge, and a reduced amphipathic character of both peptides, as compared to previously tested antimicrobial pept

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33

Reyes, Mario Felipe Gutiérrez. "EFEITO DA INCORPORAÇÃO DE NANOPARTÍCULAS DE COBRE EM UM SISTEMA ADESIVO CONVENCIONAL NAS PROPRIEDADES MICROBIOLÓGICAS, MECÂNICAS E ADESIVAS À DENTINA." UNIVERSIDADE ESTADUAL DE PONTA GROSSA, 2016. http://tede2.uepg.br/jspui/handle/prefix/1728.

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Made available in DSpace on 2017-07-24T19:22:05Z (GMT). No. of bitstreams: 1 FELIPE GUTIERREZ REYES.pdf: 2973646 bytes, checksum: 0e8c702449c97c861e9f0314e3b69e2f (MD5) Previous issue date: 2016-02-23<br>Objectives: This study evaluated the effect of addition of copper nanoparticles at different concentrations into a simplified etch-and-rinse (ER) adhesive system (Ambar [AM]) on antimicrobial activity (AMA), degree of conversion of adhesives discs (DC-d) and dentin-resin interface (DC-i), the ultimate tensile strength (UTS), 28-day cumulative water sorption (WS), solubility (So) and copper

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34

Dvoracek, Charlene M. "Antimicrobial Activity of Cationic Antiseptics in Layer-by-Layer Thin Film Assemblies." 2009. http://hdl.handle.net/1969.1/ETD-TAMU-2009-05-517.

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Layer-by-layer (LbL) assembly has proven to be a powerful technique for assembling thin films with a variety of properties including electrochromic, molecular sensing, oxygen barrier, and antimicrobial. LbL involves the deposition of alternating cationic and anionic ingredients from solution, utilizing the electrostatic charges to develop multilayer films. The present work incorporates cationic antimicrobial agents into the positively-charged layers of LbL assemblies. When these thin films are exposed to a humid environment, the antimicrobial molecules readily diffuse out and prevent bacterial

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35

Mujovo, Silva Fabiao. "Antimicrobial activity of compounds isolated from Lippia javanica (Burm.f.) Spreng and Hoslundia opposita against Mycobacterium tuberculosis and HIV-1 reverse transcriptase /." 2009. http://upetd.up.ac.za/thesis/available/etd-06042010-005807.

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