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Dissertations / Theses on the topic 'Antimicrobial application'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Loose, Christopher (Christopher R. ). "The production, design and application of antimicrobial peptides." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/38969.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2007.<br>Includes bibliographical references (p. 248-268).<br>With the spread of drug-resistant bacteria, existing antibiotics are losing their potency. Antimicrobial peptides (AmPs) represent an exciting class of drug candidates, particularly because their mechanism of action is unlikely to induce drug resistance. If resistance to AmPs were also slower to emerge in the clinic, they would have longer useful lifetimes than existing antibiotics. Nevertheless, a number of limitations exist for AmPs in the clini

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2

Ma, Minghua. "Synthesis, characterization and application of antimicrobial functional dyes /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2003. http://uclibs.org/PID/11984.

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Thesis (Ph. D.)--University of California, Davis, 2004.<br>Degree granted in Agricultural and Environmental Chemistry. Dissertation completed in 2003; degree granted in 2004. Also available via the World Wide Web. (Restricted to UC campuses).

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3

Gregg, Andrea. "The application of nanofibrous membranes with antimicrobial agents as filters." Kansas State University, 2010. http://hdl.handle.net/2097/6822.

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Master of Science<br>Department of Architectural Engineering and Construction Science<br>Julia A. Keen<br>Nanofibers are classified as fibers less than 1 micrometer in diameter. These fibers can be layered to form nanofibrous membranes, and these membranes offer great potential in the filtration industry. The membranes' smaller fiber diameters and pore sizes permit such filters to filter out more and smaller particulate. Additionally, antimicrobial agents can be incorporated into the membrane to inhibit fungal and bacterial growth on the membrane’s surface. This report evaluates nanofibrou

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Elviss, Nicola Clare. "Development and application of Helicobacter pylori surveillance to improve antimicrobial treatment." Thesis, University of Greenwich, 2005. http://gala.gre.ac.uk/6161/.

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The determination of H. pylori in vitro antibiotic susceptibility to the four key antibiotics and the underlying mechanisms of resistance were investigated. Levels of antibiotic resistance in two independent populations in England and Wales were determined. In the urban London-based population, metronidazole resistance was present in 59% and clarithromycin resistance was in 11% of the 101 H. pylori isolates. Of 363 isolates from rural Bangor, North Wales, 23% were metronidazole resistant and 7% were clarithromycin resistant. Combined clarithromycin and metronidazole resistance occurred in 9% o

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5

Pasquet, Julia. "Les nouveaux conservateurs minéraux : application à la conservation antimicrobienne de différentes formulations et étude du mécanisme antimicrobien : étude appliquée à l’oxyde de zinc." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10145.

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La qualité microbiologique d’un produit cosmétique se doit d’être conservée durant la totalité de sa durée de vie grâce à l’ajout notamment de conservateurs antimicrobiens. Néanmoins, les conservateurs organiques traditionnellement utilisés sont particulièrement décriés depuis quelques années car suspectés d’effets secondaires. Dans l’objectif de disposer d’alternatives à ces substances, les propriétés antimicrobiennes de l’oxyde de zinc (ZnO) ont été étudiées. L’efficacité antimicrobienne de ces particules inorganiques a ainsi été évaluée sur les cinq micro-organismes d’intérêt pour l’industr

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6

Rhoades, Jonathan. "The antimicrobial activity of chitosan and its application as a food preservative." Thesis, London South Bank University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288171.

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7

Khara, Jasmeet. "De novo design of antimicrobial peptides for application as anti-infective agents." Thesis, Imperial College London, 2016. http://hdl.handle.net/10044/1/45283.

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The escalating threat of antimicrobial resistance has increased pressure to develop novel therapeutic strategies to tackle drug-resistant infections. Antimicrobial peptides (AMPs) have gathered considerable interest as a new source of antibiotics due to their broad-spectrum and rapid bactericidal activities, in addition to their ability to synergise with conventional antibiotics against drug-resistant pathogens. However, natural AMPs are increasingly recognised as poor therapeutic candidates due to their long sequences, which inadvertently induce significant systemic toxicities and translate i

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8

Muriel, Galet Virginia. "Novel antimicrobial films based on ethylene-vinyl alcohol copolymers for food packaging application." Doctoral thesis, Universitat Politècnica de València, 2016. http://hdl.handle.net/10251/48522.

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This PhD dissertation thesis has been focus on the development and characterization of antimicrobial packaging films based on the incorporation in the polymer matrix or on the attachment to the film surface of naturally occurring antimicrobial compounds with the purpose of inhibiting the proliferation of microorganisms and extend the microbiological shelf life of packaged food products. The studied active films are based on the use of ethylene vinyl copolymers (EVOH) containing 29% (EVOH29) or 44% (EVOH44) molar percentage of ethylene as polymeric vehicle for the incorporation of severa

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9

Deyrieux, Charlotte. "Identification, characterisation and application of plant extracts with combined antioxidant and antimicrobial properties." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTG070.

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L’oxydation et le développement microbien constituent les paramètres majeurs à l’origine de l’altération des produits alimentaires, notamment des aliments pour animaux. Ces dégradations affectent les qualités nutritionnelles et sensorielles des produits et peuvent avoir des répercussions au niveau sanitaire. Dans ce contexte, différents moyens de prévention sont disponibles pour limiter ces phénomènes. Parmi eux, la valorisation d’ingrédients d’origine végétale à des fins alimentaires représente un enjeu majeur pour la recherche et l’industrie. Leur utilisation en tant que conservateurs nature

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10

Sabo, Sabrina da Silva. "Biotechnological production and application of antimicrobial biomolecules by Lactobacillus plantarum in milk whey." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/9/9134/tde-19102017-154411/.

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Bacteriocins are antimicrobial peptides ribosomally synthesized by various bacteria. In particular, the bacteriocins produced by lactic acid bacteria have recently received great attention due to their wide applicability and also because they are produced by microorganisms safe for human consumption. There are numerous studies reporting bacteriocin production by different lactic acid bacteria, as well as its optimization by using alternative substrate. Some of these studies point to milk/cheese whey as a potential low-cost source for the cultivation of lactic acid bacteria and the production o

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Otari, S. V., R. M. Patil, S. J. Ghosh, and S. H. Pawar. "Substrate Dependant Microbial Synthesis of Silver Nanoparticle and its Application as Antimicrobial Agent." Thesis, Sumy State University, 2012. http://essuir.sumdu.edu.ua/handle/123456789/34824.

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Microbial synthesis of nanoparticles is a green chemistry approach that interconnects nanotechnology and microbial biotechnology. In this present study, synthesis of silver nanoparticles (AgNPs) has been demonstrated using a metabolically versatile actinobacteria Rhodococcus sp. by reducing aqueous silver nitrate. The AgNPs were characterized by Ultraviolet–Visible (UV – vis) Spectrometer, Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Analysis (EDAX), Dynamic Light Scattering (DLS), Selected Area Diffraction Pattern (SAED) and Transmission Electron Microscopy (TEM). The T

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Gide, Mussie. "Design, Synthesis, Application of Biodegradable Polymers." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7625.

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Bacterial infections have posed a serious threat to the public health due to the significant rise of the infections caused by antibiotic-resistant bacteria. There has been considerable interest in the development of antimicrobial agents which mimic the natural HDPs, and among them biodegradable polymers are newly discovered drug candidates with ease of synthesis and low manufacture cost compared to synthetic host defense peptides. Herein, we present the synthesis of biocompatible and biodegradable polymers including polycarbonate polymers, unimolecular micelle hyperbranched polymers and dendri

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MORETTA, ANTONIO. "Characterization of antimicrobial peptides deriving from insects and their application in the biomedical field." Doctoral thesis, Università degli studi della Basilicata, 2021. http://hdl.handle.net/11563/150883.

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Antibiotics are the current drugs used to treat pathogenic bacteria, but their prolonged use contributes to the development and spread of drug-resistant microorganisms. The antibiotic resistance issue led to the need to find new alternative molecules, which should be less prone to bacterial resistance. Antimicrobial peptides (AMPs) aroused great interest as potential next-generation antibiotics. AMPs are involved in several defence-related processes such as the binding and neutralization of endotoxins, the modulation of the immune responses to infection and the killing of pathogens. Antimicrob

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Powis, Samantha. "Chlorine Dioxide for the Prevention of Biomaterial-Associated Infections." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1307%5F1%5Fm.pdf&type=application/pdf.

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Sundberg, Kristin L. "Application of Materials Characterization, Efficacy Testing, and Modelling Methods on Copper Cold Spray Coatings for Optimized Antimicrobial Properties." Digital WPI, 2019. https://digitalcommons.wpi.edu/etd-dissertations/511.

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The Copper Development Association (CDA) has identified over 450 copper alloys registered with the U.S. Environmental Protection Agency (EPA) as antimicrobial. With growing antibiotic resistance, there is a need for copper coatings with increased antimicrobial capability. Cold spray is a high velocity, high deposition rate process that forms dense coatings with little to no oxides or inclusions. It is possible that this process contributes to the increased antimicrobial capability of copper cold spray coatings as compared to other additive processes. The focus of this effort is to understand

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Riedel, Casper. "Ethnopharmacological evaluation through literature review and GC-MS analysis of Baccharis magellanica." [Copenhagen] : University of Copenhagen, Faculty of Life Sciences, Department of Plant Biology, 2007. http://www.forskningsbase.life.ku.dk/retrieve/6144494?format=application/pdf.

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Yang, Kewei [Verfasser], Alfred [Akademischer Betreuer] Fahr, Volker [Akademischer Betreuer] Albrecht, and Rolf [Akademischer Betreuer] Schubert. "Application of Liposomes for Antimicrobial Photodynamic Therapy / Kewei Yang. Gutachter: Alfred Fahr ; Volker Albrecht ; Rolf Schubert." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2012. http://d-nb.info/1019124989/34.

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Lanzrath, Russell. "Antimicrobial effects of multifunctional ingredients with potential application for ready to eat meat and poultry products." Kansas State University, 2016. http://hdl.handle.net/2097/32884.

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Master of Science<br>Food Science Institute<br>Elizabeth Boyle<br>Consumer demand for clean-label and 'all natural' food products has created the need to investigate antimicrobials derived from natural sources. Multifunctional ingredients are food additives that have multiple properties to reduce fat, limit salt, retard oxidation, increase water-holding capacity and inhibit bacterial growth in foods. Multifunctional ingredients that exhibit antimicrobial effects in meat and poultry products can facilitate consumers demand for clean and 'all natural' labels while reducing foodborne illness ri

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Séon, Lydie. "Polymer multilayers : fundamental aspects and application for biomaterials." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAE014/document.

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La surface d'un matériau est le lieu privilégié des interactions entre le matériau et son environnement. La technique couche-par-couche, qui consiste en un dépôt alterné de polyanions et de polycations, ouvre de nouvelles perspectives dans le domaine des biomatériaux pour le contrôle de ces interactions. La cohésion des films multicouches de polyélectrolytes est principalement assurée par des interactions électrostatiques mais a été étendue à d'autres forces motrices telles que les interactions hôte-invité. Nos travaux s’articulent autour de deux axes principaux. D’une part, nous nous sommes i

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Yang, Xu. "Brevibacillin, an Antimicrobial Lipopeptide Discovered from Genus Brevibacillus: Structural Elucidation, Mode of Action, Fermentation and Application in Commercial Apple Juice." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1483374108859293.

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Ceylan, Erdogan. "Antimicrobial activity of spices against Escherichia coli O157:H7 and their application in solid and liquid foods /." Search for this dissertation online, 2003. http://wwwlib.umi.com/cr/ksu/main.

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MAPELLI, CHIARA. "FROM FOOD WASTE TO FOOD PRESERVATION: PRODUCTION AND APPLICATION OF SAKACIN A." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/642235.

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This thesis has been conceived in the frame of a broader project named “NANOSAK- Nanocellulose–sakacin A conjugates for food packaging purposes”, financend by Fondazione Cariplo and developed in collaboration with several divisions of the Department of Food, Environmental and Nutritional Sciences (DeFENS), with the Department of Environmental Science and Policy (ESP) of the Università degli Studi di Milano and together with the Department of Food quality and preservation of the Instituto de Agroquímica y Tecnología de Alimentos (IATA), CSIC (Valencia, Spain). NANOSAK aims at exploring the us

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23

Said, J. F. S. "The application of static and flow-through isothermal microcalorimetry to the antimicrobial analysis of medical materials and devices." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1451950/.

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In the light of problematic challenges in assessing the antimicrobial properties of medical materials and devices it is necessary and important to explore novel applications of existing analytical techniques. Isothermal microcalorimetry, whether as a static or modified flow-through system, was shown to have great potential with this area. The growth and metabolism of microbes, as with any other process, involves a change in enthalpy (heat). This is measurable using isothermal microcalorimetry, allowing real-time detection of growth and changes in metabolic performance of microorganisms. While

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Figueroa, López Kelly Johana. "Biodegradable Mono and Multilayer Materials with Antimicrobial Capacity Based on Circular Bioeconomy of Application Interest in Food Packaging." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/168439.

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[ES] El envasado activo es una de las tecnologías emergentes más relevantes de la industria alimentaria. Su objetivo es interactuar con el espacio de cabeza del envase para controlar las reacciones enzimáticas, químicas, físicas y microbiológicas que deterioran los alimentos por medio de la absorción o liberación. La actual tesis doctoral trata originalmente del desarrollo y la caracterización de estructuras de envasado de alimentos activas y biodegradables mono y multicapa basadas en materiales de polihidroxialcanoatos (PHA) electroestirados derivados de estrategias de bioeconomía circular. C

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Chan, Andrea C. "The application of nanomaterials for the delivery of natural antimicrobials in engineered systems." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:9f8b7c1c-7d49-437b-9743-cb3008d89f86.

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Biofouling is the undesired biofilm formation on surfaces at a liquid interface that interferes with the affected substrate’s function. It is a ubiquitous problem in many engineered systems in industry. Biofouling causes contamination, essential damage to materials, and impedances to crucial industrial processes. These adverse effects lead to health hazards, gross increase in energy consumption, and significant decrease in overall productivity, all of which result in higher operational costs and environmentally destructive consequences. Interest in discovering effective alternatives to convent

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DUBIWAK, BIYENSA GURMESSA. "Mitigating release of contaminants with manure land application." Doctoral thesis, Università Politecnica delle Marche, 2022. http://hdl.handle.net/11566/293483.

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Questo studio si proponeva di affrontare tre obiettivi principali. In primo luogo, era mirato a caratterizzare due principali fonti di letame: letame bovino e pollame in termini di contenuto di nutrienti, composizione microbica e abbondanza di geni selezionati di resistenza agli antibiotici (Documento 1, Capitolo 1). Queste fonti di letame sono state ampiamente utilizzate come fertilizzanti nei sistemi silvopasturali in Arkansas, USA, per migliorare la produttività. Mentre il letame bovino viene applicato a terra in fresco, la lettiera di pollame, che era composta da letame di pollame e lettie

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Chen, Weixuan. "Development of Antimicrobial Agent with Novel Mechanisms of Actions and 1,2,4,5-Tetrazine Click Chemistry and its Application in DNA Postsynthetic Functionalization." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/chemistry_diss/72.

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SecA ATPase is a critical member of the Sec system, which is important in the translocation of membrane and secreted polypeptides/proteins in bacteria. Small molecule inhibitors can be very useful research tools as well as leads for future antimicrobial agent development. Based on previous virtual screening work, we optimized the structures of two hit compounds and obtained SecA ATPase inhibitors with IC50 in the single digit micromolar range. These represent the first low micromolar inhibitors of bacterial SecA and will be very useful for mechanistic studies. Post synthetic modification is an

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Kampeerapappun, Piyaporn. "The Design, Characteristics, and Application of Polyurethane Dressings using the Electrospinning Process." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1207243006.

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LIM, SANG-HOON. "SYNTHESIS OF A FIBER-REACTIVE CHITOSAN DERIVATIVE AND ITS APPLICATION TO COTTON FABRIC AS AN ANTIMICROBIAL FINISH AND A DYEING-IMPROVING AGENT." NCSU, 2002. http://www.lib.ncsu.edu/theses/available/etd-12272002-162031/.

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The purpose of this research has been to develop a textile finish based on chitosan that is a biopolymer. A fiber-reactive chitosan derivative was synthesized from chitosan with a low molecular weight and a high degree of deacetylation. The synthesis was composed of two steps. As a first step, a water-soluble chitosan derivative was prepared by introducing quaternary ammonium salt groups on the amino groups of chitosan. The derivative was further modified by introducing functional groups (acrylamidomethyl) on the primary alcohol groups of the chitosan backbone, which can form covalent bonds wi

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Azevedo, Pamela Oliveira de Souza de. "Optimization of the yield of bacteriocin-like substance (BLIS) produced by Pediococcus pentosaceus and its application as food bioconservative." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/9/9134/tde-26042018-174816/.

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Bacteriocins are peptides produced by various species of bacteria, especially lactic acid bacteria (LABs), which exhibit a large spectrum of action against spoilage bacteria and foodborne pathogens. However, when this bacteriocin has not been completely characterized regarding its amino acid and the nucleotide sequences of the corresponding gene, the qualified term bacteriocin-like inhibitory substance (BLIS) is recommended. In order to increase the antimicrobial activity of bacteriocins, the ability of probiotics LABs, such as Pediococcus pentosaceus, to ferment different carbon and nitrogen

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D'AGOSTINO, TOMMASO. "Enhanced sampling methods and their application in the study of molecular permeation in gram-negative bacteria." Doctoral thesis, Università degli Studi di Cagliari, 2016. http://hdl.handle.net/11584/266673.

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Antimicrobial resistance is inhibiting our ability to fight against pathogens. By selectively changing the composition and expression of influx water-filled proteins filling their outer membrane, gram- negative bacteria are able to reduce the rates at which specific polar compounds are able to permeate. A clear comprehension of the mechanism determining substrates diffusion through these pores is still missing. In this thesis, we show how biased computer simulations may offer a unique perspective in the study of molecular permeation through porins, overcoming the intrinsic limitations of both

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Ersoz, Tugce Irfan. "Application Of Semi Conductor Films Over Glass/ceramic Surfaces And Their Low Temperature Photocatalytic Activity." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/3/12610377/index.pdf.

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Semiconductor metal oxides can be induced by light with proper wavelength resulting in oxidation and reduction reactions for the transformation of water and oxygen molecules into active radicals. With this method, it is possible to obtain self-cleaning surfaces and products having antimicrobial properties. The aim of this study is to develop semiconductor metal oxide thin films for multifunctional glass products and the characterization of photocatalytic self cleaning and antimicrobial properties. As semiconductor metal oxides<br>titanium dioxide (TiO2), tin oxide (SnO2) and their binary mixt

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Nascimento, DemÃtrius Fernandes do. "Quantification of drugs with antimicrobial activity by high performance liquid chromatography coupled to mass spectrometry (LC-MS/MS): application in studies of comparative pharmacokinetics." Universidade Federal do CearÃ, 2011. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7045.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>Two robust, fast and sensitive methods for quantification of sulfamethoxazole (SMX), trimethoprim (TMP) and sulfadiazine (SDZ) in plasma using high performance liquid chromatography coupled to mass spectrometry (LC-MS/MS) was developed and validated. The methods involved liquid-liquid extraction with ethyl acetate using metoprolol and sulfamethoxazole as internal standards (PI). The chromatographic separations were performed using Genesis C18 column 100 x 2.1 mm, 4 microns (sulfadiazine) and Genesis C18 150 x 4.6 mm, 4 microns (S

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Alexandra, Olivia. "Potential Application of Multiplex Automated Genome Engineering (MAGE) and One-Step Curing Plasmid System for Environmental Cambodian Enterobacterial Isolates." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-449082.

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Antimicrobial resistance (AMR) is concerning because it limits antimicrobial drug treatment options. AMR occurs by the overuse and misuse of antimicrobial drugs. In environmental settings, AMR can disseminate from places of high use, which leads to increased exposure to humans and animals. A previous study from our laboratory group showed extended-spectrum cephalosporinase-producing Escherichia coli/Klebsiella pneumoniae were isolated from fecal samples obtained in rural Cambodian community settings. Based on these isolates, this study has two aims. The first aim was characterization of select

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Antunes, Stéphanie. "Agents antimicrobiens innovants de type foldamère pour le contrôle de l'infection par des pathogènes du risque biologique : application à Bacillus anthracis." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0304/document.

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Face à l’émergence de pathogènes multi-résistants aux antibiotiques classiques, et au développement des armes biologiques, la découverte de nouveaux agents antimicrobiens reste un enjeu majeur de santé public. Dans ce contexte, la conception d’oligomères peptidomimétiques, capables de mimer le caractère amphiphile et la structure en hélice des peptides antimicrobiens naturels, effecteurs clés de l’immunité innée, offre d’intéressantes perspectives. Il a été établi que des foldamères à base d’urées amphipathiques, structurés en hélice-2,5, possédaient une forte activité bactéricide contre Bacil

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Peng, Chao. "Cationic Polyurethanes for Antimicrobial Applications." University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1542383983590224.

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Alves, Cristina Jansen. "Microencapsulação de própolis utilizando matrizes proteicas para aplicação como ingrediente funcional em alimentos." Universidade Federal de Pelotas, 2018. http://guaiaca.ufpel.edu.br:8080/handle/prefix/4131.

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Submitted by Gabriela Lopes (gmachadolopesufpel@gmail.com) on 2018-08-13T20:18:31Z No. of bitstreams: 1 tese_Cristina Jansen Alves.pdf: 3092727 bytes, checksum: af2f693596976d2b32a708d78fe4713d (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2018-08-17T12:16:41Z (GMT) No. of bitstreams: 1 tese_Cristina Jansen Alves.pdf: 3092727 bytes, checksum: af2f693596976d2b32a708d78fe4713d (MD5)<br>Made available in DSpace on 2018-08-17T12:16:41Z (GMT). No. of bitstreams: 1 tese_Cristina Jansen Alves.pdf: 3092727 bytes, checksum: af2f693596976d2b32a708d78fe4713d (

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El, khawand Toni. "Extraction et hémisynthèse de stilbènes de la vigne et du vin pour une application en santé humaine et végétale." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0402.

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Les stilbènes sont des molécules de défense que produit la vigne pour lutter contre les agents pathogènes. Retrouvés dans le vin, ils acquièrent une valeur ajoutée pour leurs effets bénéfiques avérés en santé humaine. Sachant que l’efficacité des stilbènes contre certains oomycètes et champignons qui infectent la vigne augmente avec leur degré d’oligomérisation, cette thèse avait pour premier objectif d’optimiser et de procéder à des réactions de couplage oxydatif du resvératrol et de l’ɛ-viniférine extraits de sarments de vigne, en présence de sels de métaux, pour la production d’oligomères.

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Kaali, Peter. "Antimicrobial Polymer Composites for Medical Applications." Doctoral thesis, KTH, Polymera material, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-33393.

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The current study and discuss the long-term properties of biomedical polymers in vitro and invivo and presents means to design and manufacture antimicrobial composites. Antimicrobialcomposites with reduced tendency for biofilm formation should lead to lower risk for medicaldevice associated infection.The first part analyse in vivo degradation of invasive silicone rubber tracheostomy tubes andpresents degradation mechanism, degradation products and the estimated lifetime of thematerials.. It was found that silicone tubes undergo hydrolysis during the long-term exposurein vivo, which in turn res

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Brunon, Céline. "Application des caractérisations de surface par XPS, ToF-SIMS, SIMS, EELS, SEM, AFM et TEM à la compréhension des mécanismes de protection antimicrobienne de textiles modifiés par traitements de surface." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10294.

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Ce travail de thèse s’inscrit dans la partie caractérisation d’un projet collaboratif ayant pour objectif d’élaborer des textiles antimicrobiens pour différents domaines d’application, en particulier les domaines de la santé et de l’agroalimentaire. La démarche analytique a consisté à combiner différentes techniques d’analyse de surface (techniques microscopiques (SEM, AFM, TEM) et spectroscopiques (XPS, ToF-SIMS, SIMS, EELS)) avec des analyses microbiologiques pour aider à la compréhension des mécanismes de protection antimicrobienne des textiles traités. Les agents antimicrobiens, l’argent e

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Noimark, Sacha M. "Light-activated antimicrobial polymers for healthcare applications." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1470179/.

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This thesis details the development of potent light-activated antimicrobial silicone polymers for use in healthcare environments. Upon illumination, these polymers induce the lethal photosensitisation of bacteria through the generation of a range of reactive oxygen species at the polymer surface, initiating a non-site specific attack against bacteria in the vicinity. Activation of the antimicrobial technology developed was achieved using laser illumination (635 nm) and UVA illumination for medical device applications, or white hospital lighting conditions for hospital touch surface application

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Ozkan, Ekrem. "PDMS-based antimicrobial surfaces for healthcare applications." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10044839/.

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This thesis describes two types of approaches for reducing the incidence of hospital-acquired infections (HAIs), which are chemical approaches that inactivate bacteria that adhere to the surface i.e. bactericidal activity and physical approaches that inhibit initial bacterial attachment to the surface i.e. anti-biofouling activity. Specifically, the antimicrobial polydimethylsiloxane (PDMS)-based systems detailed in this thesis are: (i) photosensitizer, crystal violet (CV),-coated PDMS for both medical device and hospital touch surface applications, (ii) crystal violet-coated, zinc oxide nanop

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Bolt, Hannah Louise. "Antimicrobial peptoids : design, synthesis and biological applications." Thesis, Durham University, 2016. http://etheses.dur.ac.uk/11947/.

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The emergence of antimicrobial resistance is a severe threat to global health and new classes of antibiotics are desperately needed. Peptoids, or oligo-N-substituted glycines, are a group of peptidomimetics with increased structural stability and resistance to protease degradation compared to peptide analogues. In Chapter 1, peptoids are introduced and their antimicrobial properties reported to date are summarised. The synthesis and characterisation of one of the largest library of antimicrobial peptoids in existence is outlined in Chapter 2, comprising linear sequences and cyclic compounds. T

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Lee, Jaewoong Broughton Royall M. "Synthesis and applications of novel antimicrobial polymeric materials." Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Summer/Dissertations/LEE_JAE_27.pdf.

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Alkawareek, Mahmoud Yousef. "Antimicrobial applications of atmospheric pressure non-thermal plasma." Thesis, Queen's University Belfast, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602409.

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In this study, an in-house built atmospheric. pressure non-thermal plasma jet has been investigated for its potential utilisation as a new alternative antimicrobial tool for a variety of medical applications. Anti - biofilm activity of this plasma jet has been evaluated against biofilms of a selected panel of bacterial species, grown on different abiotic surfaces, where complete eradication of all tested bacterial biofilms was achieved after relatively short plasma exposures of up to 10 minutes. Multiple approaches of cell viability evaluation were adopted to show the nature, extent and distri

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El, Hawari Khaled. "Occurrence des résidus et contaminants chimiques dans les miels produits et consommés au Liban : développement et standardisation de méthodes de dépistage adaptées : application aux résidus d'antibiotiques." Thesis, Rennes 1, 2016. http://www.theses.fr/2016REN1B054/document.

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Une nouvelle méthode, simple et rapide, a été développée pour isoler dans le miel différents antimicrobiens usuellement recherchés en contrôle sanitaire et appartenant à quatre classes différentes: les sulfamides, les tétracyclines, les macrolides et lincosamides associés et les aminoglycosides. Ces molécules antimicrobiennes sont analysées par chromatographie liquide couplée à la spectrométrie de masse en tandem (CL-SM/SM) après avoir été extraites de l’échantillon de miel par une méthode d’extraction unique. Afin de définir les conditions optimales de séparation et de détection, l’influence

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Woo, Gregory Lu-Yuen. "Development of novel biodegradable antimicrobial polymers for biomaterials applications." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0001/MQ40915.pdf.

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Isaacs, Mark. "Nanoengineered polymer architectures for antimicrobial medical applications : novel additives." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/69607/.

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Silver is a clinically important, broad spectrum antibacterial, whose use extends back over several millennia. Its potent antibacterial activity, range of susceptible microorganisms, and lack of developed resistances, elevate silver as an exciting weapon in the fight against hospital acquired infections and so-called ‘superbugs’. The active, ionic form is efficacious at very low concentrations, thus controlling release rates offers potential durable, non-specific, antibacterial medical devices. This thesis examines a number of inorganic systems as potential slow-release, antibacterial silver n

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Godard, Jérémy. "Synthèse et caractérisation de nouveaux dérivés de phénalénone pour des applications environnementales et antimicrobiennes." Thesis, Limoges, 2020. http://aurore.unilim.fr/theses/nxfile/default/82f127f9-677e-433b-af18-c48fb664739d/blobholder:0/2020LIMO0077.pdf.

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Un photosensibilisateur est un composé capable de capter les rayonnements lumineux et de transférer cette énergie à des molécules voisines. En particulier, l'oxygène moléculaire peut capter cette énergie pour aboutir à de l’oxygène singulet, une forme de l’oxygène extrêmement réactive capable de détruire une grande variété de composés organique dont les constituants cellulaires et les polluants environnementaux. Avec un rendement quantique de production d'oxygène singulet proche de 1 dans tous les solvants, la phénalénone est un excellent photosensibilisateur qui présente l'avantage d'être syn

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Uche, Cosmas Chinedu. "Fabrication of nanomaterials from biomass for adsorption and antimicrobial applications." University of the Western Cape, 2020. http://hdl.handle.net/11394/7330.

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Philosophiae Doctor - PhD<br>The Black soldier fly (BSF) is an environmentally friendly and sustainable insect utilised in the decomposition of organic waste. This is due to its voracious consumption capability, disruptive functions and economic importance. The sustained global increase in commercial BSF farming has resulted in an expanded waste generation from its carcases to which beneficial uses ought to be developed. This study focused on the beneficial use of the generated waste by extracting chitosan from waste pupae and commercially reared BSF adult carcases. The study also considered t

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