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1

Sanford, Jay P. Guide to antimicrobial therapy, 1993. Dallas, TX: Antimicrobial Therapy, Inc., 1993.

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2

A, Snow G., ed. Biochemistry of antimicrobial action. 4th ed. London: Chapman and Hall, 1989.

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3

Franklin, T. J. Biochemistry of antimicrobial action. 4th ed. London: Chapman and Hall, 1985.

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4

Sanford, Jay P. Guide to antimicrobial therapy 1994. Dallas, Tex: J.P. Sanford, 1994.

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5

Sanford, Jay P. Guide to antimicrobial therapy 1994. Dallas, Tex: J.P. Sanford, 1994.

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6

Jenssen, Havard. Antimicrobial activity of lactoferrin and lactoferrin derived peptides. Hauppauge, NY: Nova Science, 2009.

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7

1935-, Greenwood David, and O'Grady Francis, eds. The scientific basis of antimicrobial chemotherapy: Thirty-eighth Symposium of the Society for General Microbiology, held at the University of Nottingham Medical School, September 1985. Cambridge [Cambridgeshire]: Cambridge University Press, 1985.

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8

Williams, R. A. D. Antimicrobial drug action. Oxford: BIOS Scientific, 1996.

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9

Lück, Erich. Antimicrobial food additives: Characteristics, uses, effects. 2nd ed. Berlin: Springer, 1997.

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10

Abramowicz, Mark. Handbook of antimicrobial therapy. New Rochelle, N.Y: Medical Letter, 2002.

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11

Abramowicz, Mark. Handbook of antimicrobial therapy. New Rochelle, N.Y: Medical Letter, 2002.

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12

M, Eliopoulos George, ed. Sanford guide to antimicrobial therapy 2010. 4th ed. Sperryville, Va: Antimicrobial Therapy, 2010.

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13

Yang, Xu. A Study on Antimicrobial Effects of Nanosilver for Drinking Water Disinfection. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-2902-8.

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14

The Sanford guide to antimicrobial therapy 2010. 4th ed. Sperryville, VA: Antimicrobial Therapy, 2010.

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15

1950-, Georgopapadakou Nafsika H., ed. Drug transport in antimicrobial and anticancer chemotherapy. New York: Marcel Dekker, 1995.

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16

D, Barug, ed. Antimicrobial growth promoters: Where do we go from here? [Wageningen] The Netherlands: Wageningen Academic Publishers, 2006.

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17

F, Harrison Polly, Lederberg Joshua, and Institute of Medicine (U.S.). Forum on Emerging Infections., eds. Antimicrobial resistance: Issues and options : workshop report. Washington, D.C: National Academy Press, 1998.

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18

Erik, Nord Carl, ed. Consequences of antimicrobial therapy for the composition of the microflora of the digestive tract. Herborn-Dill: Institute for Microbiology and Biochemistry, 1993.

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19

Moriarty, T. Fintan. Biomaterials Associated Infection: Immunological Aspects and Antimicrobial Strategies. New York, NY: Springer New York, 2013.

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20

Svinhufvud, Lillemor Borthen. Selective modulation of the oropharyngeal microflora with topical administration of antimicrobial agents. Stockholm: Kongl Carolinska Medico Chirurgiska Institutet, 1987.

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21

Diver, Jonathan Michael. The uptake of quinolone antimicrobial agents into Escherichia coli: Transport mechanisms and physiological effects on cells. Birmingham: University of Birmingham, 1987.

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22

L, Yu Victor, Merigan Thomas C. 1934-, and Barriere Steven L, eds. Antimicrobial therapy and vaccines: Editors, Victor L. Yu, Thomas C. Merigan, Steven L. Barriere ; associate editors, Alan M. Sugar ... [et al.]. Baltimore: Williams & Wilkins, 1999.

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23

(WHO), World Health Organization. Antimicrobial Resistance: Global Report on Surveillance. WHO Regional Office for the Western Pacific, 2014.

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24

Biochemistry and Molecular Biology of Antimicrobial Drug Action. Springer, 2005.

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25

Franklin, T. J., and G. A. Snow. Biochemistry and Molecular Biology of Antimicrobial Drug Action. Springer, 2013.

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26

Unknown. Biochemistry and Molecular Biology of Antimicrobial Drug Action. 5th ed. Springer, 2007.

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27

Mendelson, Marc. Antimicrobial stewardship in a resource-poor setting. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0018.

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Low- and middle-income countries (LMICs) face a high burden of infection and, commonly, colliding epidemics of HIV, malaria, tuberculosis, and other bacterial diseases. The resulting high usage of antimicrobials, inappropriate prescribing, and use of falsified or counterfeit medicines drives antimicrobial resistance. Stewardship programmes need to be developed within the social and cultural norms of the country, and take cognizance of competing health needs, which may prove important barriers. A situational analysis of the country’s resources and challenges with respect to antimicrobial resistance and the need for regional and international collaboration to effect change are important first steps to establishing a programme. Identifying, developing, and unifying stewardship champions aids in the translation of policy into practice. Leadership at the highest level is required in partnership with national government. While resource limitations are a significant barrier to stewardship programmes, concentrating on low-hanging fruit allows LMICs to develop meaningful programmes to combat antimicrobial resistance.
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28

Murdande, Sharad B. The disposition of four therapeutically important antimicrobial agents in llamas. 1994.

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29

Coliforms in distribution systems: Integrated disinfection and antimicrobial resistance. Denver, CO: Awwa Research Foundation, 2007.

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30

Springthorpe, Susan, Graham E. C. Gagnon, Heather M. Murphy, Jennie L. Rand, Sarah Jane Payne, Fernando Matias, Reza Nokbeh, and Syed A. Sattar. Coliforms in Distribution Systems:: Integrated Disinfection and Antimicrobial Resistance. American Water Works Research Foundation, 2007.

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31

The Evolving Threat Of Antimicrobial Resistance Options For Action. World Health Organization, 2012.

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32

A Guide to sensitivity testing: Report of the Working Party on Antibiotic Sensitivity Testing of the British Society for Antimicrobial Chemotherapy. London: Academic Press, 1991.

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33

Scobie, Antonia, Mark Gilchrist, Laura Whitney, and Matthew Laundy. Managing antimicrobials on the shop floor. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0005.

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Reducing antimicrobial usage is key to stewardship, reducing adverse effects, and potentially stemming the tide of resistance. Establishment of an antimicrobial team on the shop floor to develop and manage a practical programme is discussed. Suggested methods of reducing antimicrobial usage include preventing initiation of unnecessary antimicrobials by the use of evidence-based guidelines and biomarker-directed clinical pathways, restricting durations to the shortest effective course—with automatic stop orders and separate antibiotic prescription charts, parenteral to oral switch programmes and utilization of outpatient parenteral antimicrobial therapy services when available. Finally, cessation of inappropriate treatment and reducing the use of broad-spectrum antimicrobials are essential and can be achieved by restrictive strategies such as pre-authorization and persuasive strategies such as audit and feedback via stewardship ward rounds. Different approaches to implementing audit and feedback within hospitals are covered in detail in this chapter.
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34

Walton, Katherine E., and Sally Ager. Antimicrobial agents. Edited by Rob Pickard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0002.

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Antimicrobial resistance is a growing problem, which can be exacerbated by inappropriate use of antimicrobial agents. An understanding of the judicious use of antimicrobial agents, also known as antimicrobial stewardship, is therefore of fundamental importance to safe clinical practice. Patient factors should also be considered, including age, clinical status, special factors such as pregnancy or immunosuppression, co-morbidities, allergies, medication which may result in potential drug interactions, previous microbiology results, and antimicrobial treatment history. Important antimicrobial characteristics include the drug’s spectrum of activity, routes of administration, potential side effects, and cost. This chapter provides an overview of the ways in which antibacterial agents work and how bacteria develop resistance. It also outlines the principles of safe antimicrobial prescribing for prophylaxis and therapy, and highlights the key features, clinical indications, and potential adverse effects of antibacterial and antifungal agents commonly used in urology.
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35

Meylers Side Effects Of Antimicrobial Drugs. Elsevier Science & Technology, 2009.

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36

Aronson, Jeffrey K. Meyler's Side Effects of Antimicrobial Drugs. Elsevier Science & Technology Books, 2009.

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37

Lueck, Erick. Antimicrobial Food Additives: Characteristics - Uses - Effects. Springer, 2012.

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38

Antimicrobial Food Additives: Characteristics - Uses - Effects. Springer, 2011.

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39

Lück, Erich, and Martin Jager. Antimicrobial Food Additives: Characteristics, Uses, Effects. 2nd ed. Springer, 1997.

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40

Estes, Lynn L., and John W. Wilson. Antimicrobials. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199755691.003.0412.

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This chapter approaches the field of infectious diseases from 3 perspectives. This third section reviews antimicrobial agents. The mechanisms of action, spectrums of activity, clinical uses, routes of excretion, and toxic effects of various antimicrobial agents are emphasized. Antibacterials such as penicillins, cephalosporins, carbapenems, aminoglycosides, tetracyclines, and fluoroquinolones are reviewed. Antifungals such as the azoles, polyenes, and echinocandins are also covered. Antivirals such as acyclovir, famciclovir, oseltamivir, and foscarnet are included as well.
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41

Laundy, Matthew, Mark Gilchrist, and Laura Whitney, eds. Antimicrobial Stewardship. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.001.0001.

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The problem of antimicrobial-resistant organisms and untreatable infections is of global concern. The concept of antimicrobial stewardship has been developing over the last 10 years. The aim of antimicrobial stewardship is to control antimicrobial use in order to reduce the development of resistance, avoid the side effects associated with antimicrobial use, and optimize clinical outcomes. This book provides a very practical approach to antimicrobial stewardship. It’s very much a ‘how to’ guide supported by a review of the available evidence. Section 1 sets the scene and covers the problem of antimicrobial resistance; the problems in the antimicrobial supply line and initiatives to improve the situation; the principles and goals of antimicrobial stewardship; the psychological, social, cultural, and organizational factors in antimicrobial use and prescribing; and how to establish an antimicrobial stewardship programme. Section 2 reviews the components of antimicrobial stewardship: audit and feedback; antimicrobial policies and formularies; antimicrobial restriction; intravenous to oral switch; measuring antimicrobial consumption; measuring and feeding back stewardship; and the use of information technology in antimicrobial stewardship. Section 3 explores special areas in antimicrobial stewardship: antimicrobial pharmacokinetics and pharmacodynamics; intensive care units; paediatrics; surgical prophylaxis; near-patient testing and infection biomarkers; antimicrobial stewardship in the community and long-term care facilities; and finally antimicrobial stewardship in resource-poor communities.
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42

Lambert, Dr Pete. ANTIMICROBIAL DRUG ACTION (Medical Perspectives). Garland Science, 1996.

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43

Ahmed, Syud Amer, Enis Baris, Delfin S. Go, Hans Lofgren, Israel Osorio-Rodarte, and Karen Thierfelder. Assessing the Global Economic and Poverty Effects of Antimicrobial Resistance. World Bank, Washington, DC, 2017. http://dx.doi.org/10.1596/1813-9450-8133.

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44

Protocol for Enhanced Isolate-Level Antimicrobial Resistance Surveillance in the Americas. Primary Phase: Bloodstream Infections. Pan American Health Organization, 2021. http://dx.doi.org/10.37774/9789275122686.

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Antimicrobial resistance (AMR) surveillance plays an important role in the early detection of resistant strains of public health importance and prompt response to outbreaks in hospitals and the community. Surveillance findings are needed to inform medical practice, antibiotic stewardship, and policy and interventions to combat AMR. Appropriate use of antimicrobials, informed by surveillance, improves patients’ treatment outcomes and reduces the emergence and spread of AMR. This protocol describes the steps and procedures to establish/enhance AMR surveillance in Latin America and the Caribbean. It provides technical guidance to integrate patient, laboratory, and epidemiological data to monitor AMR emergence, trends, and effects in the population. It also provides the necessary elements to move from aggregated data to isolate-level data surveillance starting with blood isolates. It facilitates uniform data collection processes, methods, and tools to ensure data comparability within the Region of the Americas. Finally, it builds on over a decade of experience of the regional AMR surveillance network—ReLAVRA by its Spanish acronym—and its procedures are aligned with the Global Antimicrobial Resistance Surveillance System (GLASS) methodology, enabling countries to participate in the global GLASS AMR surveillance.
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45

Institute of Medicine (Corporate Author), Polly F. Harrison (Editor), and Joshua Lederberg (Editor), eds. Antimicrobial Resistance: Issues and Options. National Academy Press, 1998.

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46

Pai, Manjunath P., Keith A. Rodvold, Jennifer J. Kiser, and Paul O. Gubbins. Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions. Humana, 2019.

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47

Pai, Manjunath P., Keith A. Rodvold, Jennifer J. Kiser, and Paul O. Gubbins. Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions. Humana, 2018.

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48

Yang, Xu. A Study on Antimicrobial Effects of Nanosilver for Drinking Water Disinfection. Springer, 2018.

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49

Yang, Xu. A Study on Antimicrobial Effects of Nanosilver for Drinking Water Disinfection. Springer, 2016.

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50

Robb, Fiona, and Andrew Seaton. What are the principles and goals of antimicrobial stewardship? Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0002.

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Antimicrobial stewardship (AS) is a coordinated strategy for quality improvement designed to improve the appropriate use of antimicrobial agents to optimize clinical outcomes whilst minimizing collateral antimicrobial effects including antimicrobial resistance andClostridium difficileinfection. AS is a function of the multidisciplinary antimicrobial management team and is dependent on key relationships with infection protection and control, clinical governance, therapeutic, and medical management structures within a healthcare organization. AS should operate within a national framework and is driven by quality improvement and patient safety. Engagement with prescribers through education, surveillance, and audit and feedback are key to the success of an AS programme.
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