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Dissertations / Theses on the topic 'Antimicrobial minimum inhibitory concentration'

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1

Markopoulos, Marjorie M. "Antimicrobial Activity of Fractionated Borohydride-Capped and Electrochemical Colloidal Silver." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright1515096508634157.

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2

Cetin-Karaca, Hayriye. "EVALUATION OF NATURAL ANTIMICROBIAL PHENOLIC COMPOUNDS AGAINST FOODBORNE PATHOGENS." UKnowledge, 2011. http://uknowledge.uky.edu/gradschool_theses/652.

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Raw and processed foods are vulnerable to contamination during their production, distribution and sale. Thus, a wide variety of chemical preservatives are used in the food industry to prevent the growth of food spoilage and pathogenic bacteria. However, health and economic concerns have led to an intensive search for natural alternatives, such as plant extracts, that can safely be used as substitutes for synthetic antimicrobials and preservatives to partially or completely inhibit the growth of bacteria. This study evaluated the antimicrobial effects of natural phenolic compounds extracted fro
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3

Noll, Alexander J. "Cerium oxide nanoparticles for the detection of antimicrobial resistance." Honors in the Major Thesis, University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/486.

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The rise of antimicrobial resistance demands the development of more rapid screening methods for the detection of antimicrobial resistance in clinical samples to both give the patient the proper treatment and expedite the treatment of patients. Cerium oxide nanoparticles may serve a useful role in diagnostics due to their ability to exist in a mixed valence state and act as either oxidizing agents or reducing agents. Considering that cerium oxide nanoparticles have been shown to shift in absorbance upon oxidation, a useful method of antimicrobial resistance detection could be based on the oxid
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4

DeDonder, Keith David. "Antimicrobial resistance and bovine respiratory disease; a pharmacokinetic/pharmacodynamic approach to macrolide resistance." Diss., Kansas State University, 2015. http://hdl.handle.net/2097/20602.

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Doctor of Philosophy<br>Diagnostic Medicine/Pathobiology<br>Michael D. Apley<br>Bovine respiratory disease (BRD) remains a major disease in beef production systems. The administration of antimicrobials for both the control and treatment of acute BRD is common. According to most published accounts, antimicrobial resistance among BRD pathogens is increasing; therefore, judicious antimicrobial usage is vital for continued efficacy. The introduction of a novel antimicrobial class has not occurred for well over a decade, therefore it is paramount to maximize efficacy of the antimicrobials currentl
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Garaicoa, Pazmino Jorge Luis. "Minimal inhibitory concentration of antimicrobial and antifungal agents in denture adhesive material against Candida albicans." Thesis, University of Iowa, 2014. https://ir.uiowa.edu/etd/1458.

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Approximately 26% of the U.S. population between the ages of 65 and 74 years are completely edentulous. Of the different proposed predictors and risk factors, low income and education levels have the highest correlation with tooth loss. While the incidence of complete edentulism in the United States has progressively declined over the past decade, the continued growth of the population strongly suggests that edentulism prevalence will likely remain constant or increase over the next few decades. In patients wearing complete prosthetic appliances, several post-treatment complications may arise,
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Aziz, Seemal. "Antibiotic Susceptibility Testing: Effects Of Variability In Technical Factors On Minimum Inhibitory Concentration Using Broth Microdilution." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454819.

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Background Broth microdilution (BMD) is a gold-standard reference method to determine minimum inhibitory concentration (MIC) of antibiotics. For this, a standardized concentration of bacterial inoculum (2e5–8e5 colony-forming units, CFU/ml) is added to progressively higher concentrations of antibiotics. Bacteria stop growing at a particular antibiotic concentration termed MIC. Like other assays, various biological and/or technical factors can affect BMD results.   Aims To investigate the effects of inoculum concentration (5e4–5e6 CFU/ml), growth-medium concentration (cation-adjusted Mueller-Hi
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Maisuria, Bhadreshkumar B. "Synthesis, Characterization, Critical Micelle Concentration and Antimicrobial Activity of Two-headed Amphiphiles." Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/34607.

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This project is about the synthesis of homologous series of two-headed, long-chain amphiphiles (the 2CCbn series, where n = 16, 18, 20, 22, 30, 5α-cholestan-3à -ol). The 2CCbn series was synthesized in five steps. The first step involves a reaction of nitroethane and two equivalents of tert-butyl acrylate to form nitrodiester by successive Michael addition reaction. The second step is the reduction of nitrodiester with Raney nickel to form aminodiester. The third step involves a reaction of aminodiester with di-tert-butyl dicarbonate [(Boc)2O] to form isocyanatediester. The fourth step is add
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Jonker, Annelize. "Antimicrobial susceptibility in thermophilic Campylobacter species isolated from pigs and chickens in South Africa." Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/27117.

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The thermophilic Campylobacters, Campylobacter jejuni and Campylobacter coli are found as commensals in the intestinal tract of healthy mammals and birds. Campylobacter jejuni is one of the leading causes of sporadic food-borne bacterial disease in humans which is predominantly contracted from poultry products. Although the vast majority of these infections are mild, life-threatening complications should be treated with antimicrobials. Patients are usually treated with either macrolides of fluoroquinolones. However, globally there is an increased trend in the development of resistance to these
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9

Pieruzzi, Paula Adriane Piccolo. "Estudo da determinação da concentração inibitória mínima do muco de Achatina fulica sobre Staphylococcus aureus ATCC 25923." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-04062013-144801/.

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A mastite bovina apresenta alta prevalência nos rebanhos leiteiros e a antibioticoterapia é o procedimento mais utilizado no tratamento da mesma. O Staphylococcus aureus, agente etiológico mais frequentemente isolado em casos de mastite, tem demonstrado em diversos estudos aumento crescente no padrão de resistência aos antimicrobianos. O desenvolvimento de bactérias resistentes e a presença de resíduos de antimicrobianos no leite estimulam o desenvolvimento de novos tratamentos que solucionem estes problemas. O muco dos moluscos Achatina fulica é composto por uma glicoproteína, denominada acha
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10

França, Paula 1987. "Investigação genética e funcional da produção de compostos antimicrobianos por bactérias oriundas da Antártica = Genetic and functional evaluation of production of antimicrobial compounds by bacteria from Antarctica." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316713.

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Orientadores: Fabiana Fantinatti Garboggini, Marta Cristina Teixeira Duarte<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-26T21:03:15Z (GMT). No. of bitstreams: 1 Franca_Paula_M.pdf: 7905078 bytes, checksum: 6735b6d77cec7c206090abaa6e56fdfc (MD5) Previous issue date: 2015<br>Resumo: Os micro-organismos associados ao continente Antártico apresentam populações diversas e metabolicamente ativas, porém o potencial farmacológico dos compostos obtidos pelos micro-organismos é pouco conhecido. As bactérias são importante
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Silva, Leandro Prezotto da. "Avaliação da atividade antimicrobiana da N,N,Ntrimetilquitosana e da quitosana comercial sobre o crescimento de bactérias gram-positivas e gram-negativas e de fungos filamentosos." Universidade Federal de São Carlos, 2014. https://repositorio.ufscar.br/handle/ufscar/7036.

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Made available in DSpace on 2016-08-17T18:39:51Z (GMT). No. of bitstreams: 1 6095.pdf: 2718900 bytes, checksum: c4d734a7b2927b9a3c31ecfb042e26bd (MD5) Previous issue date: 2014-04-16<br>Many efforts have been dedicated in the searching of natural compounds which are suitable to be applied in food conservation. Among them, the chitosan has presented promising results concerning the antimicrobial activity, structural preservation and delay of fruits senescence. However, the chitosan, as found commercially, is soluble only in acidic medium solutions what is considered a hindrance for fully appl
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OLIVEIRA, Tiago Branquinho. "Estudo Farmacognóstico, Investigação das Atividades Antimicrobiana, Leishmanicida e Toxicidade Aguda de Rhamnidium elaeocarpum Reissek RHAMNACEAE (Cafezinho)." Universidade Federal de Goiás, 2009. http://repositorio.bc.ufg.br/tede/handle/tde/2128.

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Made available in DSpace on 2014-07-29T16:11:53Z (GMT). No. of bitstreams: 1 dissertacao tiago oliveira.pdf: 60590 bytes, checksum: 2becac23a5f99abe922b4af561c0a7d1 (MD5) Previous issue date: 2009-08-27<br>In the last years the treatment with medicines made from medicinal plants has increased. A concern about the useful of these natural products is the quality control pharmacobotanical, phytochemical and purity tests, which make up the technical specifications of a particular plant species. Moreover, pharmacological and toxicological studies must be conducted in order to effectiveness and sa
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Silva, Juliana de Cassia 1984. "Nanopartículas de prata : biossíntese, investigação das atividades antibacteriana, antifúngica e citotoxicidade." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/244483.

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Orientador: Patricia da Silva Melo, Priscyla Daniely Marcato<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Aplicadas<br>Made available in DSpace on 2018-08-26T08:22:25Z (GMT). No. of bitstreams: 1 Silva_JulianadeCassia_M.pdf: 2326263 bytes, checksum: 5774dc06c3b8cd0a38cfb05b3dbd8247 (MD5) Previous issue date: 2014<br>Resumo: Com o objetivo de entender melhor a toxicidade das nanopartículas de prata biogênicas, estas foram preparadas utilizando a rota biotecnológica e extracelular com o fungo Fusarium oxysporum. As nanopartículas de prata biogênicas fora
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Holbrook, Selina Y. L. "DISCOVERY OF NEW ANTIMICROBIAL OPTIONS AND EVALUATION OF AMINOGLYCOSIDE RESISTANCE ENZYME-ASSOCIATED RESISTANCE EPIDEMIC." UKnowledge, 2018. https://uknowledge.uky.edu/pharmacy_etds/89.

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The extensive and sometimes incorrect and noncompliant use of various types of antimicrobial agents has accelerated the development of antimicrobial resistance (AMR). In fact, AMR has become one of the greatest global threat to human health in this era. The broad-spectrum antibiotics aminoglycosides (AGs) display excellent potency against most Gram-negative bacteria, mycobacteria, and some Gram-positive bacteria, such as Staphylococcus aureus. The AG antibiotics amikacin, gentamicin, kanamycin, and tobramycin are still commonly prescribed in the U.S.A. for the treatment of serious infections.
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15

Mantovani, Cristina Kampus. "Diversidade e atividade antimicrobiana de bactérias isoladas de esponjas marinhas." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316715.

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Orientador: Fabiana Fantinatti-Garboggini<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-18T12:39:46Z (GMT). No. of bitstreams: 1 Mantovani_CristinaKampus_M.pdf: 1137189 bytes, checksum: 2db8a522e2d39a0ae80a5e302d4d79e8 (MD5) Previous issue date: 2011<br>Resumo: Nas últimas décadas um grande número de compostos de interesse biotecnológico, como por exemplo, citotoxinas, agentes antifúngicos, antimicrobianos, antivirais e anticancerígenos têm sido isolados de esponjas marinhas. Entretanto, estudos comprovam que, em m
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Cerqueira, Valdeane Dias. "Composi??o qu?mica do ?leo essencial de Lippia origanoides Kunth e atividade antimicrobiana frente a diferentes sorotipos de Haemophilus parasuis." Universidade Estadual de Feira de Santana, 2014. http://localhost:8080/tede/handle/tede/123.

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Submitted by Natalie Mendes (nataliermendes@gmail.com) on 2015-07-28T23:01:37Z No. of bitstreams: 1 COMPOSI??O QU?MICA DO ?LEO ESSENCIAL DE Lippia origanoides Kunth E ATIVIDADE ANTIMICROBIANA FRENTE A DIFERENTES SOROTIPOS~1.pdf: 1434340 bytes, checksum: 8072381e4bdaa1aac1583317e834ac0d (MD5)<br>Made available in DSpace on 2015-07-28T23:01:37Z (GMT). No. of bitstreams: 1 COMPOSI??O QU?MICA DO ?LEO ESSENCIAL DE Lippia origanoides Kunth E ATIVIDADE ANTIMICROBIANA FRENTE A DIFERENTES SOROTIPOS~1.pdf: 1434340 bytes, checksum: 8072381e4bdaa1aac1583317e834ac0d (MD5) Previous issue date: 2014-03
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Osei-Boadi, Kate. ""An aliphatic essential amino acid influences the expression of host defense peptides in colonic epithelial cells: in vitro findings and potential clinical implications in Crohn's disease"." Diss., Kansas State University, 2014. http://hdl.handle.net/2097/17629.

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Doctor of Philosophy<br>Department of Human Nutrition<br>Tonatiuh Melgarejo<br>Background and Objective: Crohn’s disease (CD) patients express low levels of host defense peptides (HDPs) especially β-defensins, which may compromise intestinal barrier function. Antibiotic treatment for bacterial infections in CD is limited and rarely curative, making it necessary to find alternative therapeutic approaches. We therefore investigated to what extent an essential amino acid; L-isoleucine (L-ILE) might induce the expression of human β-defensins (HBDs) in colonic epithelial cells as an alternative ap
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18

Andrade, Mariana Roque de. "Perfil de suscetibilidade a antimicrobianos de isolados históricos de Staphylococcus hyicus comparado com isolados contemporâneos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/71573.

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O presente estudo teve o objetivo de avaliar o perfil de sensibilidade in vitro de 171 isolados de Staphylococcus hyicus a nove antimicrobianos utilizados na suinocultura. A coleta das amostras foi realizada através de suabes de pele de leitões das fases de maternidade e creche provenientes de casos de epidermite exsudativa. As amostras foram submetidas ao isolamento e identificação e compreenderam dois grupos, classificadas de acordo com o período em que foram coletadas. O primeiro grupo foi formado por amostras históricas (80 isolados) provenientes de estudos anteriores entre 1975 a 1984 no
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Chaul, Luiza Toubas. "Caracterização e determinação da atividade antimicrobiana dos extratos brutos e frações de Rosmarinus officinalis Linn. (alecrim), Origanum vulgare Linn. (orégano) e Capsicum chinense Jacq. (pimenta habanero)." Universidade Federal de Goiás, 2015. http://repositorio.bc.ufg.br/tede/handle/tede/4560.

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Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2015-05-21T15:04:30Z No. of bitstreams: 2 Dissertação - Luiza Toubas Chaul - 2015.pdf: 1642322 bytes, checksum: e56380dae120d4058880c94d9e953832 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2015-05-21T15:07:38Z (GMT) No. of bitstreams: 2 Dissertação - Luiza Toubas Chaul - 2015.pdf: 1642322 bytes, checksum: e56380dae120d4058880c94d9e953832 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Made a
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Faria, Maria Juíva Marques de. "Oleorresina de Copaifera spp.: caracterização, verificação da atividade antimicrobiana in vitro e avaliação preliminar de uma formulação em vacas leiteiras com mastite." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/3939.

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Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2014-12-22T14:31:16Z No. of bitstreams: 1 Dissertação - Maria Juíva Marques de Faria - 2014.pdf: 3781718 bytes, checksum: 5a98e4c3d48dde6e80b58427a1a73012 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2015-01-26T13:13:18Z (GMT) No. of bitstreams: 1 Dissertação - Maria Juíva Marques de Faria - 2014.pdf: 3781718 bytes, checksum: 5a98e4c3d48dde6e80b58427a1a73012 (MD5)<br>Made available in DSpace on 2015-01-26T13:13:18Z (GMT). No. of bitstreams: 1 Dissertação - Maria Juíva Marques de Faria - 2014.pdf: 3781
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Oliveira, Dayanne Rakelly de. "SILIMARINA MODIFICA A ATIVIDADE DA NA+/K+-ATPASE E DA MAO E MODULA A AÇÃO DE ANTIMICROBIANOS IN VITRO." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/4493.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The Silymarin is a flavonolignan complex isolated from milk thistle seeds of Silybum marianum being used in the treatment of injury related to oxidative stress, including liver and neurological diseases, as Parkinson disease. Although silymarin has been reported to possess a variety of pharmacological properties including anti-inflammatory, anticarcinogenic and neuroprotective effects, information regard its antimicrobial and drug modulator potential against microbial resistance is scanty in the literature. In addition, the possibl
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Knostman, Hayley. "Minimum inhibitory concentration (MIC) assay assessment of the bactericidal properties of triclosan and ampicillin." Ohio Dominican University Honors Theses / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=oduhonors1430745733.

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Souza, Juliete Gomes de Lara de. "Composição química, atividade antioxidante, acaricida e antimicrobiana de extratos vegetais e do óleo essencial das folhas de Zanthoxylum Caribaeum l. frente a sorotipos de salmonella de origem avícola." Universidade Estadual do Oeste do Paraná, 2017. http://tede.unioeste.br/handle/tede/3472.

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Submitted by Edineia Teixeira (edineia.teixeira@unioeste.br) on 2018-03-05T14:21:12Z No. of bitstreams: 2 Juliete_Souza2017.pdf: 1034930 bytes, checksum: b1f11241cc86452c59ec27f91ef18252 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Made available in DSpace on 2018-03-05T14:21:12Z (GMT). No. of bitstreams: 2 Juliete_Souza2017.pdf: 1034930 bytes, checksum: b1f11241cc86452c59ec27f91ef18252 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-03-08<br>The genus Zanthoxylum comprises species distributed throughou
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Mota, Milena Rodrigues Soares. "Análise da atividade antimicrobiana de extratos e frações purificadas da planta arrabidaea chica verl." Universidade Federal do Amazonas, 2011. http://tede.ufam.edu.br/handle/tede/4384.

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Submitted by Alisson Mota (alisson.davidbeckam@gmail.com) on 2015-07-13T19:08:16Z No. of bitstreams: 1 Tese - Milena Rodrigues Soares Mota.pdf: 10830184 bytes, checksum: b6f2977c2b749cd675523693c33de0ff (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2015-07-15T17:58:31Z (GMT) No. of bitstreams: 1 Tese - Milena Rodrigues Soares Mota.pdf: 10830184 bytes, checksum: b6f2977c2b749cd675523693c33de0ff (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2015-07-15T18:07:20Z (
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Wentzel, Jeanette Maria. "A comparative study of the minimum inhibitory and mutant prevention concentrations of florfenicol and oxytetracycline for animal isolates of Pasteurella multocida and Salmonella Typhimurium." Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/26219.

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This study was undertaken to compare the MIC (minimum inhibitory concentration) and MPC (mutant prevention concentration) values for oxytetracycline and florfenicol against strains of Pasteurella multocida isolated from cattle and pigs, and for enrofloxacin against strains of Salmonella Typhimurium isolated from horses. Isolates of P. multocida from cattle and pigs, and S. Typhimurium from horses were obtained from specimens or isolates from contributing laboratories. All the equine isolates and 50% of the cattle and pig isolates were from clinically sick animals. All isolates were tested in d
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Zaffarano, Jennifer I. "Minimum inhibitory concentration of two common food phenolic compounds and their effects on the microbial ecology of swine feces in vitro." Lexington, Ky. : [University of Kentucky Libraries], 2003. http://lib.uky.edu/ETD/ukyansc2003t00099/JZThesis.pdf.

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Thesis--University of Kentucky (M.S.), 2003.<br>Title from document title page. Document formatted into pages; contains ix, 127 p. : ill. Includes abstract and vita. Includes bibliographical references (p. 110-126).
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Bui, Hanh. "A COMPARISON OF TWO COMMERCIAL STRIPS WITH PREDEFINED ANTIBIOTIC CONCENTRATION GRADIENTS FOR SUSCEPTIBILITY TESTING OF PERIODONTAL BACTERIAL PATHOGENS." Master's thesis, Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/216515.

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Oral Biology<br>M.S.<br>Objectives: Systemic antibiotics are generally recognized as providing a beneficial impact in treatment of both aggressive and chronic periodontitis. Since strains of periodontal pathogens among periodontitis patients may vary in their antibiotic drug resistance, the American Academy of Periodontology recommends antimicrobial susceptibility testing of suspected periodontal pathogens prior to administration of systemic periodontal antibiotic therapy, to reduce the risk of a treatment failure due to pathogen antibiotic resistance. E-test and MIC Test Strip assays are two
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Toledo, Adrieli Gorlin. "Composição química e atividades biológicas das folhas de Eugenia involucrata DC." Universidade Estadual do Oeste do Paraná, 2018. http://tede.unioeste.br/handle/tede/3882.

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Wilcox, Ashley M. "Silver Nanoparticles: An effective antibacterial agent against Gram-negative bacteria." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1576621225597745.

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Peterson, Gregory Jay. "Factors that affect horizontal gene transfer in enteric bacteria." Diss., Kansas State University, 2011. http://hdl.handle.net/2097/13891.

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Doctor of Philosophy<br>Department of Diagnostic Medicine/Pathobiology<br>Sanjeev Narayanan<br>Antimicrobial resistance (AMR) has arisen as one of the most important public health concerns in the last 60 years. AMR results from pathogenic strains of bacteria adapting to antimicrobial-containing environments through mutations or through horizontal gene transfer (HGT) of genetic material containing resistance genes. Conjugation machinery offers an efficient method for acquisition of AMR and virulence genes, which may be responsible for propelling the evolution of pathogenic bacteria. This disser
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White, Rebekah. "A Physiologically-Based Pharmacokinetic Model for Vancomycin." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/honors/308.

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Vancomycin is an antibiotic used for the treatment of systemic infections. It is given intravenously usually every twelve or twenty-four hours. This particular drug has a medium level of boundedness, with approximately fty percent of the drug being free and thus physiologically eective. A physiologically-based pharmacokinetic (PBPK) model was used to better understand the absorption, distribution, and elimination of the drug. Using optimal parameters, the model could be used in the future to test how various factors, such as BMI or excretion levels, might aect the concentration of the antibiot
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Culbreath, Marci. "An Investigation into the Antifungal Activities of N-Thiolated Beta- Lactams Against Selected Candida Species." [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001633.

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Felizardo, Maria Roberta. "Caracterização fenotípica e genotípica de isolados de Bordetella bronchiseptica provenientes de diferentes espécies animais." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-01092015-143702/.

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Bordetella bronchiseptica é um agente respiratório zoonótico comumente encontrado em diversars espécies animais domésticos como cães, gatos, coelhos, suínos, aves e equinos. As infecções em humanos ocorrem ocasionalmente, sendo descritas com maior freqüência em indivíduos imunocomprometidos, mas relatos de casos de doença em adultos saudáveis e crianças têm aumentado. O presente estudo teve como objetivos determinar o perfil de resistência antimicrobiana de cepas de B. bronchiseptica isoladas de cães, gatos, coelhos e suínos, caracterizar as cepas pela eletroforese em campo pulsado (PFGE), e
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Pinheiro, Denise Jaqueto de Barros. "Determinação da concentração inibitória mínima de antibióticos contra ureaplasmas isolados de bovinos pela inibição de crescimento e citometria de fluxo." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-24072012-161250/.

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Os Mollicutes causam doenças em várias espécies animais de importância econômica, inclusive em bovinos. Neste estudo, foi avaliada por concentração inibitória mínima (CIM) e citometria de fluxo, a atividade de oito agentes antibacterianos (enrofloxacina, ciprofloxacina, gentamicina, claritromicina, cloranfenicol, oxitetraclina, tiamulina e tilosina) contra Ureaplasma diversum. Foram analisadas 24 amostras de isolados de campo oriundas da mucosa genital de fêmeas bovinas. As amostras foram confirmadas por crescimento em caldo, placa e por PCR. Os inóculos foram submetidos à analise de suscetibi
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McCartt, Paezha M. "A Physiologically-Based Pharmacokinetic Model for the Antibiotic Levofloxacin." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/honors/343.

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Levofloxacin is in a class of antibiotics known as fluoroquinolones, which treat infections by killing the bacteria that cause them. A physiologically-based pharmacokinetic (PBPK) model was developed to investigate the uptake, distribution, and elimination of Levofloxacin after a single dose. PBPK modeling uses parameters such as body weight, blood flow rates, partition coefficients, organ volumes, and several other parameters in order to model the distribution of a particular drug throughout the body. Levofloxacin is only moderately bound in human blood plasma, and, thus, for the purposes of
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Pereira, Carolina Silva Guimarães. "Perfil da Sensibilidade Microbiana de Bactérias Isoladas nos Olhos de Cães com Ceratoconjuntivite Seca." Universidade do Oeste Paulista, 2016. http://bdtd.unoeste.br:8080/tede/handle/tede/741.

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Made available in DSpace on 2016-07-18T17:53:17Z (GMT). No. of bitstreams: 1 Carolina Silva Guimaraes Pereira.pdf: 713350 bytes, checksum: d2adc7dea782d58a041a7b1b5991ba9c (MD5) Previous issue date: 2016-05-06<br>This study aims to evaluate the microbial sensitivity profile of bacteria isolated from the eyes of dogs with keratoconjunctivitis sicca (KCS). We evaluated 65 dogs (n=65) diagnosed with KCS and 30 healthy dogs (c=30) (control group). After diagnosis of KCS, conjunctival swabs were collected and the microbiological examinations performed under aerobic culture, antibiogram and minimu
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Leite, Renata de Freitas. "Concentração inibitória mínima de extratos brutos produzidos por actinobactérias para agentes causadores de mastite bovina." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-23112016-152350/.

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O uso imprudente de antibióticos para o tratamento da mastite bovina pode levar ao aumento da resistência bacteriana e ao comprometimento da eficácia dos tratamentos atuais. Desta maneira, novas alternativas para o tratamento da mastite devem ser procuradas. As actinobactérias são capazes de produzir extratos brutos que contêm metabólitos secundários ativos, que inibem o crescimento de outras bactérias. Portanto, o presente estudo teve como objetivo avaliar a concentração inibitória mínima (CIM) de extratos brutos de actinobactérias para isolados de Staphylococcus aureus, Staphylococcus chromo
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Tello, Gildemeister Alfredo. "A study into the effects and environmental risk of antibiotics used in freshwater aquaculture on environmental bacteria." Thesis, University of Stirling, 2012. http://hdl.handle.net/1893/9930.

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Aquaculture is the fastest growing food industry in the world and it accounts for roughly half of the world's fish supply. The majority of global aquaculture production occurs in freshwater systems that are increasingly subject to multiple uses by different stakeholders. Given the overall scarcity of freshwater on a global scale, freshwater aquaculture will face increasing environmental constraints that will demand an ever better understanding of its potential impacts on the aquatic environment and human health. This thesis consists of a series of studies that, collectively, contribute to furt
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Quadros, Cedenir Pereira de. "Estudo do potencial de aplicação industrial de uma mistura composta de lipase alcalina de Fusarium oxysporum e biossurfatante de Bacillus subtilis." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/256670.

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Orientador: Glaucia Maria Pastore<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos<br>Made available in DSpace on 2018-08-13T13:08:43Z (GMT). No. of bitstreams: 1 Quadros_CedenirPereirade_D.pdf: 2098145 bytes, checksum: bb56ba34ac3fa84f3dc7493e47485a6d (MD5) Previous issue date: 2009<br>Resumo: Na perspectiva de se tornar uma alternativa aos produtos já existentes para a indústria, foi proposto neste trabalho uma mistura inédita e original composta por uma lipase alcalina (LA) produzida por Fusarium oxysporum e biossurfatante (BS) produzido por B
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Mariano, Valeria. "A study of tetracycline resistant Escherichia coli in impala (Aepyceros melampus) and their water sources." Diss., Pretoria : [s.n.], 2008. http://upetd.up.ac.za/thesis/available/etd-02192009-140903/.

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Sarkar, Aurijit. "DEVELOPMENT AND APPLICATIONS OF THE HINT FORCEFIELD IN PREDICTION OF ANTIBIOTIC EFFLUX AND VIRTUAL SCREENING FOR ANTIVIRALS." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2266.

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This work was aimed at developing novel tools that utilize HINT, an empirical forcefield capable of quantitating both hydrophobic and hydrophilic (hydropathic) interactions, for implementation in theoretical biology and drug discovery/design. The role of hydrophobicity in determination of macromolecular structure and formation of complexes in biological molecules is undeniable and has been the subject of research across several decades. Hydrophobicity is introduced, with a review of its history and contemporary theories. This is followed by a description of various methods that quantify this
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Ryu, Victor. "Use Of Different Ripening Inhibitors To Enhance Antimicrobial Activity Of Essential Oil Nanoemulsion." 2017. https://scholarworks.umass.edu/masters_theses_2/584.

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The objective of this research was to study the impact of ripening inhibitor level and type on the formation, stability, and activity of antimicrobial thyme oil nanoemulsions formed by spontaneous emulsification. Oil-in-water antimicrobial nanoemulsions (10 wt%) were formed by titrating a mixture of essential oil, ripening inhibitor, and surfactant (Tween 80) into 5mM sodium citrate buffer (pH 3.5). Stable nanoemulsions containing small droplets (d < 70 nm) were formed. The antimicrobial activity of the nanoemulsions decreased with increasing ripening inhibitor concentration, which was attribu
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Rollo, Susan Noble. "Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin." Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9755.

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The purpose of this dissertation is threefold: to determine the differences in apparent prevalence and the antimicrobial susceptibility of Campylobacter spp. between antimicrobial-free and conventional swine farms; secondly, to introduce an appropriate statistical model to compare the minimum inhibitory concentration distributions of Escherichia coli and Campylobacter spp. isolated from both farm types; and thirdly, to examine the potential herd level risk factors that may be associated with antimicrobial resistance of Campylobacter spp. and E. coli isolates from finishers on antimicrobial-fre
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Otto, Simon James Garfield. "ANTIMICROBIAL RESISTANCE OF HUMAN CAMPYLOBACTER JEJUNI INFECTIONS FROM SASKATCHEWAN." Thesis, 2011. http://hdl.handle.net/10214/2658.

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Saskatchewan is the only province in Canada to have routinely tested the antimicrobial susceptibility of all provincially reported human cases of campylobacteriosis. From 1999 to 2006, 1378 human Campylobacter species infections were tested for susceptibility at the Saskatchewan Disease Control Laboratory using the Canadian Integrated Program for Antimicrobial Resistance Surveillance panel and minimum inhibitory concentration (MIC) breakpoints. Of these, 1200 were C. jejuni, 129 were C. coli, with the remaining made up of C. lari, C. laridis, C. upsaliensis and undifferentiated Campylobacter s
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Poirier, Etienne. "L'antibiorésistance acquise des bactéries de la glande mammaire et des intestins en fonction des traitements intramammaires de tarissement chez les bovins laitiers." Thèse, 2007. http://hdl.handle.net/1866/7169.

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Gomes, Maria do Rosário Almeida. "Determinação da concentração mínima inibitória aos carbapenemos por citometria de fluxo." Master's thesis, 2018. http://hdl.handle.net/10400.14/31713.

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Entre os beta-lactâmicos, os carbapenemos são os antimicrobianos mais eficazes contra bactérias Gram-negativo. O aparecimento de bactérias multirresistentes ameaça seriamente essa classe de fármacos que salvam vidas. A determinação de concentrações mínimas inibitórias (CMI) aos antibióticos é atualmente considerada importante quer para o tratamento destas infeções quer para o controlo epidemiológico. Este estudo propõe um novo teste de suscetibilidade antimicrobiana baseado em citometria de fluxo para determinação rápida da CMI aos carbapenemos diretamente de hemoculturas positivas. Noventa e
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Brinco, Catarina Alexandra Gomes. "Evolution of antifungal drug tolerance in Candida albicans." Master's thesis, 2018. http://hdl.handle.net/10773/25138.

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Nowadays, fungal infections are a serious public health issue due to the increasing drug resistance and small number of antifungals available. Candida albicans is the most prevalent human fungal pathogen, causing invasive fungal infections that are associated with high mortality rates. This fungus has a particular hybrid tRNA (tRNACAGSer) that is recognized by both the leucyl - and the seryl-tRNA synthetases (LeuRS and SerRS), allowing for incorporation of leucine (3%) and serine (97%) at CUG positions. It has already been shown that in the presence of antifungals, the level of Leu misincorp
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Cochrane, Roger. "Interventional strategies to reduce biological hazards in animal feed." Diss., 2018. http://hdl.handle.net/2097/39014.

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Doctor of Philosophy<br>Department of Animal Sciences and Industry<br>Cassandra K. Jones<br>Porcine epidemic diarrhea virus (PEDV) is a heat-sensitive virus that devastated the United States swine industry. Because of its heat sensitivity, it was hypothesized that a pellet mill mimicking commercial thermal processing may mitigate PEDV infectivity. From the results, it was determined that a conditioning time of 30 sec or greater and temperatures above 54.4°C were effective point-in-time kill steps to inactive PEDV in a research setting. However, this does not prevent subsequent recontamination
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Guenther, Phatchanok. "Efficacy of disinfectants against multidrug-resistant Enterobacter cloacae strains isolated from humans in a clinical setting." 2020. https://ul.qucosa.de/id/qucosa%3A73091.

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Einführung: Enterobacter (E.) cloacae subsp. cloacae sind wichtige Humanpathogene, insbesondere bei stationär untergebrachten Patienten. Sie sind in der Lage, Medizinprodukte zu kontaminieren, und es wurde über nosokomiale Krankheitsausbrüche in Verbindung mit der Kolonisation von chirurgischen Utensilien berichtet. Es ist daher wichtig, die Wirksamkeit und Effizienz von Desinfektionsmitteln gegenüber dieser Bakterienart zu bestimmen. Ziele: Die aktuelle Studie wurde durchgeführt, um nachzuweisen, ob Peressigsäure, Ethanol, Benzalkoniumchlorid und Natriumhypochlorit, welche weit verbreitet in
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Murei, Arinao. "Synthesis, Characterization and Evaluation of Novel Treatment against Resistant Pathogenic Bacteria." Diss., 2018. http://hdl.handle.net/11602/1343.

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MSc (Microbiology)<br>Department of Microbiology<br>BACKGROUND: Antibiotic resistance amongst microbial pathogens has become a challenge over past decades, bringing about genuine and frequently deadly contaminations that can't be dealt with by ordinary means. This has led to a search on developing solutions to this problem by searching for new source of antimicrobial agents or chemically altering the existing ones. Traditional medicinal plants and nanoparticles are highly targeted as promising agents to address the challenge. Pyrenacantha grandiflora Baill from Icacenaceae family possess pharm
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