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1

Livorsi, Daniel J., Carrie M. Linn, Bruce Alexander, Brett H. Heintz, Traviss A. Tubbs, and Eli N. Perencevich. "The Value of Electronically Extracted Data for Auditing Outpatient Antimicrobial Prescribing." Infection Control & Hospital Epidemiology 39, no. 1 (2017): 64–70. http://dx.doi.org/10.1017/ice.2017.250.

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OBJECTIVEThe optimal approach to auditing outpatient antimicrobial prescribing has not been established. We assessed how different types of electronic data—including prescriptions, patient-visits, and International Classification of Disease, Tenth Revision (ICD-10) codes—could inform automated antimicrobial audits.DESIGNOutpatient visits during 2016 were retrospectively reviewed, including chart abstraction, if an antimicrobial was prescribed (cohort 1) or if the visit was associated with an infection-related ICD-10 code (cohort 2). Findings from cohorts 1 and 2 were compared.SETTINGPrimary ca
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Jelinski, Murray, Andrea Kinnear, Karen Gesy, et al. "Antimicrobial Sensitivity Testing of Mycoplasma bovis Isolates Derived from Western Canadian Feedlot Cattle." Microorganisms 8, no. 1 (2020): 124. http://dx.doi.org/10.3390/microorganisms8010124.

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Mycoplasma bovis is particularly adept at evading the immune system, resulting in chronic infections of the lungs and joints of feedlot cattle. The chronicity of the lesions results in prolonged antimicrobial therapy, possibly exacerbating antimicrobial resistance. This cross-sectional study generated in vitro antimicrobial susceptibility testing (AST) data on 211 M. bovis isolates recovered from 159 healthy, diseased, and dead cattle, spanning the period of 2006–2018. Nine antimicrobials commonly administered to western Canadian feedlot cattle were assessed. The data were analyzed with non-pa
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3

Vasilyeva, I. A., A. E. Panova, V. V. Tinkova, et al. "Antimicrobial resistance of Mycobacterium avium during the COVID-19 pandemic." Clinical Microbiology and Antimicrobial Chemotherapy 26, no. 4 (2024): 462–69. https://doi.org/10.36488/cmac.2024.4.462-469.

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Objective. Conduct a comparative assessment of the frequency and spectrum of antimicrobial resistance of Mycobacterium avium isolated from patients of a phthisiopulmonology clinic in the pre-Covid period (2018–2019) and during the COVID-19 pandemic (2020–2023). Materials and Methods. The antimicrobial sensitivity of M. avium isolates was determined to 8 antimicrobial drugs: amikacin, clarithromycin, linezolid, moxifloxacin, ciprofloxacin, doxycycline, rifabutin, rifampicin. Drug susceptibility testing was performed using serial broth microdilution method according to published CLSI guidelines,
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Bhatta, Sabita, Manoj Pradhan, Alina Singh, Raina Chaudhary, and Yankpam Ibotomba Singh. "Antimicrobial Sensitivity Pattern of Pseudomonas Aeruginosa Isolated from a Tertiary Care Hospital." Medical Journal of Shree Birendra Hospital 19, no. 2 (2020): 70–74. http://dx.doi.org/10.3126/mjsbh.v19i2.28380.

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Introduction: Pseudomonas aeruginosa (P. aeruginosa) is one of the major cause of nosocomial infection. Multi-drug-resistant P. aeruginosa (MDR PA) are increasingly encountered in clinical samples .Therefore, this study was undertaken to know the sensitivity pattern of P. aeruginosa and to detect MDR PA from clinical samples.
 Methods: This was a laboratory based retrospective-cross sectional study conducted at Department of Microbiology at a tertiary care referral centre in Kathmandu, Nepal from December 2018 to December 2019. Total of 200 isolates of P. aeruginosa were isolated from cli
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Kang, Jihun, Martin Wiedmann, Kathryn J. Boor, and Teresa M. Bergholz. "VirR-Mediated Resistance of Listeria monocytogenes against Food Antimicrobials and Cross-Protection Induced by Exposure to Organic Acid Salts." Applied and Environmental Microbiology 81, no. 13 (2015): 4553–62. http://dx.doi.org/10.1128/aem.00648-15.

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ABSTRACTFormulations of ready-to-eat (RTE) foods with antimicrobial compounds constitute an important safety measure against foodborne pathogens such asListeria monocytogenes. While the efficacy of many commercially available antimicrobial compounds has been demonstrated in a variety of foods, the current understanding of the resistance mechanisms employed byL. monocytogenesto counteract these stresses is limited. In this study, we screened in-frame deletion mutants of two-component system response regulators associated with the cell envelope stress response for increased sensitivity to commer
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Kumari, Manjari, Suparna Chatterjee, Tapas Som, and Pinaki Chattopadhyay. "Antimicrobial usage and its quantification for neonatal sepsis at a tertiary care hospital neonatal intensive care unit." International Journal of Basic & Clinical Pharmacology 8, no. 9 (2019): 2046. http://dx.doi.org/10.18203/2319-2003.ijbcp20194114.

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Background: Antimicrobial therapy for neonatal sepsis is challenging as its judicious use can save neonates while its inappropriate use can lead to rapid emergence of resistant strains. Quantification of consumption of antimicrobial agents (AMA) has not been undertaken in Indian neonatal intensive care units (NICU) setting. This prospective observational study evaluated the antimicrobial prescribing pattern and quantified its consumption in clinically suspected neonatal sepsis (NS) cases.Methods: Clinically suspected NS cases admitted over study period of 18 months in a tertiary care level III
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Saleh, Ahmed Abu, Syed Shaukat Ahmed, Moniruzzaman Ahmed, Abu Naser Ibne Sattar, and Md Ruhul Amin Miah. "Changing trends in Uropathogens and their Antimicrobial sensitivity pattern." Bangladesh Journal of Medical Microbiology 3, no. 2 (2010): 9–12. http://dx.doi.org/10.3329/bjmm.v3i2.5320.

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In order to monitor changes in the etiologic bacterial agents and as well as antimicrobial resistance of urinary pathogens between five years period and over several years, urinary culture and sensitivity result of patients attending the outpatient departments of Bangabandhu Sheikh Mujib Medical University (BSMMU) in 2003 and in 2008 were analyzed retrospectively. In 2003 and 2008, 668 and 715 cultures respectively were reviewed. The frequency of Escherichia coli dropped significantly in the outpatient clinics from 60.02% to 51.75%. The frequency of Klebsiella spp increased considerably. The f
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Shahriar, M., and S. Akter. "A Survey on Antimicrobial Sensitivity Pattern of Different Antibiotics on Clinical Isolates of Pseudomonas aeruginosa Collected from Dhaka City of Bangladesh." Journal of Scientific Research 3, no. 1 (2010): 187. http://dx.doi.org/10.3329/jsr.v3i1.6014.

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A study of antimicrobial sensitivity of Pseudomonas aeruginosa isolated from clinical sources from different diagnostic centers, Dhaka, Bangladesh was carried out to facilitate the preference of drug in the management of Pseudomonas aeruginosa induced symptoms. Very low sensitivity of P. aeruginosa towards co-trimoxazole (45%), azithromycin (30%) and erythromycin (35%) was observed. Higher sensitivity pattern was observed for cefuroxime (57.5%). and only imipenem (100%) has shown sensitivity pattern possibly susceptible enough to consider for the management of P. aeruginosa induced cases in th
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Márquez, Maria Luisa Fernández, María José Grande Burgos, Rubén Pérez Pulido, Antonio Gálvez, and Rosario Lucas López. "Correlations among Resistances to Different Antimicrobial Compounds in Salmonella Strains from Hen Eggshells." Journal of Food Protection 81, no. 2 (2018): 178–85. http://dx.doi.org/10.4315/0362-028x.jfp-17-200.

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ABSTRACT Persistence of antibiotic-resistant Salmonella in the food chain may depend on strain tolerance to other antimicrobials and also on biofilm formation capacity. Yet, there is limited information on sensitivity of antibiotic-resistant Salmonella to other antimicrobials, such as phenolic compounds, chemical preservatives, or antimicrobial peptides. This study aimed at correlating antimicrobial resistance and biofilm formation capacity in antibiotic-resistant, biocide-tolerant Salmonella strains from hen eggshells. A collection of 21 strains previously selected according to their antibiot
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Wong, Jeffrey Man Hay, Denise J. Wooding, Sarah E. Leung, Vanessa Paquette, Ashley Roberts, and Chelsea Elwood. "Establishing obstetrics-specific metrics and interventions for antimicrobial stewardship." Journal of the Association of Medical Microbiology and Infectious Disease Canada 8, no. 2 (2023): 116–24. http://dx.doi.org/10.3138/jammi-2022-0032.

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Background: To describe baseline antimicrobial stewardship (AMS) metrics and apply AMS interventions in an inpatient obstetrical population. Methods: From October 2018 to October 2019, our tertiary-care obstetrical center reviewed components of our AMS program, which included: (1) antimicrobial consumption data, (2) point prevalence surveys (PPS), and (3) prospective audit and feedback. We reviewed institutional data for antimicrobial consumption from the pharmacy database. Detailed point prevalence surveys were conducted for all antimicrobial prescriptions on two predefined dates each month.
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Gancho, Olga V., Tetiana D. Bublii, Oleksij P. Kostyrenko Oleksij P. Kostyrenko, and Vira I. Fedorchenko. "ANTIMICROBIAL EFFECT OF CITRATE BUFFER WITH ANTIBIOTIC." Eastern Ukrainian Medical Journal 10, no. 1 (2022): 80–87. http://dx.doi.org/10.21272/eumj.2022;10(1):80-87.

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Antibiotic resistance of pathogens to medications is an essential problem globally. Thus, new medication compositions are one of the ways to solve this problem. This study aimed to investigate the antimicrobial efficacy of the citrate buffer combined with the antibiotic «Amoxiclav» on standard reference strains of microorganisms. We used standard cultures of C. albicans ATCC10231, E. coli ATCC25922, S. aureus ATCC25923, E. faecalis ATCC29213, M. luteus ATCC4698, S. epidermidis ATCC14990 in the study conducted at the Microbiology, Virology and Immunology Department of the Poltava State Medical
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Deecken, B. P., F. Freitas, K. V. Bassetto, A. G. Strider, and B. G. Castro. "Fracture exposed in Blue-yellow-macaw (Ara ararauna, L., 1758) infected with multiresistant Pseudomonas aeruginosa - Case Report." Scientific Electronic Archives 13, no. 11 (2020): 56. http://dx.doi.org/10.36560/131120201081.

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Antibiotics are used to prevent or treat bacterial infections; however, the emergence of antimicrobial resistance is one of the major problems in human and veterinary medicine. Little is known about the prevalence of bacterial antimicrobial resistant associated with wild animals. Moreover, birds are susceptible to several bacterial pathogens common to man. In this sense, Pseudomonas aeruginosa has great relevance, causing infections when the host's defense mechanisms are reduced. The objective of this study was to report a case of isolation of a multidrug-resistant strain of P. aeruginosa in a
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Ameen, Syed S., Shanmukananda Prakash, Laxminarayana Bairy K., and Shahabuddin Soherwardi. "Antimicrobial drug sensitivity pattern of Pseudomonas aeruginosa in respiratory infections." International Journal of Basic & Clinical Pharmacology 6, no. 7 (2017): 1591. http://dx.doi.org/10.18203/2319-2003.ijbcp20172635.

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Background: Pseudomonas aeruginosa, a gram-negative pathogen commonly associated with nosocomial infections is the most widespread multidrug-resistant pathogen causing pneumonia in hospitalized patients. Inadequate empirical therapy has been associated with high mortality and morbidity. Objective: To evaluate and analyze the antimicrobial susceptibility pattern of P. aeruginosa in respiratory infections in a tertiary care hospital.Methods: The study was carried out at Kasturba Hospital, Manipal from Jan 2011 to Dec 2011. Specimens of 63 in-patients were analyzed who were culture positive for P
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Sieswerda, Elske, Thijs Bosch, Jacqueline M. Lankelma, Leo M. Schouls, and Karin van Dijk. "Vitek® 2 MICs as first-line phenotypic screening method for carbapenemase-producing Pseudomonas aeruginosa." Future Microbiology 16, no. 11 (2021): 777–81. http://dx.doi.org/10.2217/fmb-2020-0024.

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Aim: To define sensitivity and specificity of Vitek® 2 MICs as phenotypic screening method for carbapenemase-producing Pseudomonas aeruginosa. Materials & methods: We determined Vitek® 2 MICs of antipseudomonal antimicrobials in 130 unrelated carbapenemase-producing P. aeruginosa and 129 carbapenemase-negative P. aeruginosa isolates within a Dutch carbapenemase-surveillance database. We calculated test characteristics of single and combined antimicrobial MICs for carbapenemase production. Results: Vitek® 2 MIC above epidemiological cutoff of both imipenem and tobramycin or ciprofloxacin an
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Ali, Md Khoyber, and Shahin Sultana. "Antimicrobial sensitivity patterns of salmonella typhi in children." Bangladesh Journal of Medical Science 15, no. 3 (2016): 416–18. http://dx.doi.org/10.3329/bjms.v15i3.30198.

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Background: Enteric fever is an important public health problem in developing countries including Bangladesh. A changing antibiotic sensitivity pattern of Salmonella typhi and emergence of resistance has increased to a great concern. Objective: Aim of the study was to investigate the antibiotic sensitivity pattern of Salmonella typhi. Methods: A total of 181 Salmonella typhi samples from 5 to 15 years age group were collected from blood culture during the period of October to December 2014 from IBN SINA Hospital, Dhaka, Bangladesh. Specimens from the blood culture were identified by standard p
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Khare, Anubhuti, Saroj Kothari, and Vaibhav Misra. "Incidence and sensitivity pattern of Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa in a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 6, no. 2 (2017): 329. http://dx.doi.org/10.18203/2319-2003.ijbcp20170324.

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Background: Antimicrobial resistance is a serious problem worldwide and differs from region to region. This study was planned to determine the incidence and sensitivity pattern of Klebsiella pneumoniae (K. pneumoniae), Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa) in our region and discuss the general issues related to antimicrobial resistance.Methods: Prospective study was carried out between March to October 2015. Samples of urine, blood, pus, CSF and miscellaneous samples (fluids, swabs, sputum and stool) were collected from indoor and outdoor patients for isolation
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Taha, Ahmed E., Abdulbaqi S. Alduraywish, Ali A. Alanazi, et al. "High Bacterial Contamination Load of Self-Service Facilities in Sakaka City, Aljouf, Saudi Arabia, with Reduced Sensitivity to Some Antimicrobials." Microorganisms 11, no. 12 (2023): 2937. http://dx.doi.org/10.3390/microorganisms11122937.

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Although self-service facilities (SSFs) have been used on a large scale worldwide, they can be easily contaminated by microorganisms from the hands of their sequential users. This research aimed to study the prevalence and antimicrobial susceptibility/resistance of bacteria contaminating SSFs in Sakaka, Aljouf, Saudi Arabia. We randomly swabbed the surfaces of 200 SSFs, then used the suitable culture media, standard microbiological methods, and the MicroScan WalkAway Microbiology System, including the identification/antimicrobial susceptibility testing-combo panels. A high SSFs’ bacterial cont
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Ahmed, Farzana, Aftab Yousuf Raj, Lutfun Nahar, and Zahidul Hasan. "Antimicrobial resistance of bacterial pathogens in a Neonatal Intensive Care Unit." Bangabandhu Sheikh Mujib Medical University Journal 11, no. 1 (2018): 25. http://dx.doi.org/10.3329/bsmmuj.v11i1.35133.

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<p class="Abstract">The aim of this study was to identify the antimicrobial susceptibility pattern and relevant treatment options in a neonatal intensive care unit from January 2012 and June 2016. Out of the total 78 culture positive samples, Gram positive and Gram negative microorganisms were 26% and 74% respectively. <em>Acinetobacter</em> remained the predominant isolate (32.1%) followed by <em>Klebsiella</em> species (18.0%). Most of the Gram positive isolates exhibited higher resistance to penicillin, cephalosporin, macrolides, gentamycin and quinolones. Gram
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WAHYUDI, MARIANA, and Antonius Adji Prayitno Setiadi. "PENGOLEKSIAN ISOLAT- ISOLAT Pseudomonas aeruginosa DARI PASIEN DI SURABAYA DAN PEMETAAN KEPEKAANNYA TERHADAP BERBAGAI MACAM ANTIBIOTIKA." Sains & Teknologi 1, no. 3 (2019): 35. http://dx.doi.org/10.24123/jst.v1i3.2236.

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The investigation about collectivity and sensitivity test of Pseudomonas aeruginosa from patient in Surabaya have been done. The aim of this research is to collect the bacteria from patient and to know the profile of their sensitivity toward the variety of antimicrobial agents. P. aeruginosa isolates were collected from two microbiological laboratory in Surabaya. Then, each isolate was purified and reconfirmed of few of its properties. Purified P. aeruginosa collections were then store in –70oC . Sensitivity test for each isolate was done toward 13 kinds of antimicrobial agents. The conclusion
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McCoy, Andrea J., Hongjian Liu, Timothy J. Falla, and John S. Gunn. "Identification of Proteus mirabilisMutants with Increased Sensitivity to Antimicrobial Peptides." Antimicrobial Agents and Chemotherapy 45, no. 7 (2001): 2030–37. http://dx.doi.org/10.1128/aac.45.7.2030-2037.2001.

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ABSTRACT Antimicrobial peptides (APs) are important components of the innate defenses of animals, plants, and microorganisms. However, some bacterial pathogens are resistant to the action of APs. For example,Proteus mirabilis is highly resistant to the action of APs, such as polymyxin B (PM), protegrin, and the synthetic protegrin analog IB-367. To better understand this resistance, a transposon mutagenesis approach was used to generate P. mirabilismutants sensitive to APs. Four unique PM-sensitive mutants of P. mirabilis were identified (these mutants were >2 to >128 times more sensitiv
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ULLAH, G., F. AHSAN, S. FARRUKH, MA QAISRANI, M. YASIN, and M. AKHTAR. "ANTIMICROBIAL SENSITIVITY PATTERN OF PEDIATRIC CYSTIC FIBROSIS PATIENTS IN PAKISTAN." Biological and Clinical Sciences Research Journal 2023, no. 1 (2023): 492. http://dx.doi.org/10.54112/bcsrj.v2023i1.492.

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Cystic fibrosis (CF) is a complex genetic disorder affecting the respiratory and digestive systems, causing recurrent infections. This study aimed to evaluate the microbiological cultures and identify the patterns of antimicrobial sensitivity among young CF patients in Pakistan. This prospective observational study was conducted at the Pakistan Institute of Medical Sciences (PIMS) from December 2021 to November 2022, involving comprehensive assessments, interviews, clinical tests, MTs, CBCs, CXRs, sputum cultures, RBS measurements, microbiological analysis of sputum and oropharyngeal swabs, an
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Tadee, Phacharaporn, Wiwat Pattanawong, Apichart Manwicha, et al. "Bacterial Pathogens of Bovine Mastitis: Prevalence, Antimicrobial Susceptibility, and Sensitivity to Caesalpinia sappan Both In Vitro and In Vivo Studies." Biology 14, no. 4 (2025): 350. https://doi.org/10.3390/biology14040350.

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Mastitis is a major infectious disease that causes significant economic losses in the dairy industry. Current control programs primarily rely on antimicrobials, contributing to the growing concerns of the resistance situation and drug residues in milk. This study aimed to identify the bacterial pathogens responsible for subclinical/clinical bovine mastitis, assess their antimicrobial resistance profiles, and evaluate the antimicrobial effects of Caesalpinia sappan in treating mastitis through both in vitro and in vivo studies. A total of 138 bacterial isolates, representing 40 species, were id
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Araújo, Matéus Simplício, Antônio Evandro de Sousa Silva, and Júlio César Sousa Prado. "Antimicrobial Sensitivity Associated with Porphyromonas gingivalis Present in Periodontitis Frameworks: An Integrative Review." Archives of Current Research International 24, no. 2 (2024): 50–69. http://dx.doi.org/10.9734/acri/2024/v24i2633.

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Objectives: The Gram-negative anaerobic bacterium Porphyromonas gingivalis is identified as one of the most important causes of the chronic form of periodontitis. This work aimed to analyze the sensitivity of P. gingivalis to antibiotics and antimicrobial agents.
 Study Design: Integrative literature review.
 Methodology: Through a careful analysis of clinical trials published in the last 5 years. A bibliographic search was carried out in the PubMed, Scielo and Google Scholar databases. Three keywords were established and verified on the DeCs-Descritores em Ciências da Saúde website
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Parveen, Nighat, Vineeta Khare, Sarah Hassan, and Syed Abid Asghar. "PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF PSEUDOMONAS AERUGINOSA ISOLATED FROM VARIOUS CLINICAL SAMPLES AT ELMC&H." Era's Journal of Medical Research 10, no. 01 (2023): 25–28. http://dx.doi.org/10.24041/ejmr2023.4.

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To identify P. aeruginosa prevalence in different clinical samples along with to. Evaluate its antibiotic sensitivity method isolated from variety of clinical. Over the course of the six- month trial period, 1200 samples in total were analyzed. To identify and isolate P. aeruginosa, each of them underwent direct microscopy and culture. In this study 63 P. aeruginosa were isolated and identified out of 1200 clinical samples. Pus and urine were where the majority of P. aeruginosa were isolated from specimens. There found sensitivity to Piperacilin- tazobactam (10µg) 35% and Gentamycin (10µg) 38%
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Reece, Emma, Pedro H. de Almeida Bettio, and Julie Renwick. "Polymicrobial Interactions in the Cystic Fibrosis Airway Microbiome Impact the Antimicrobial Susceptibility of Pseudomonas aeruginosa." Antibiotics 10, no. 7 (2021): 827. http://dx.doi.org/10.3390/antibiotics10070827.

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Pseudomonas aeruginosa is one of the most dominant pathogens in cystic fibrosis (CF) airway disease and contributes to significant inflammation, airway damage, and poorer disease outcomes. The CF airway is now known to be host to a complex community of microorganisms, and polymicrobial interactions have been shown to play an important role in shaping P. aeruginosa pathogenicity and resistance. P. aeruginosa can cause chronic infections that once established are almost impossible to eradicate with antibiotics. CF patients that develop chronic P. aeruginosa infection have poorer lung function, h
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Stultz, Jeremy S., Perry Taylor, and Sean McKenna. "Assessment of Different Methods for Pediatric Meningitis Dosing Clinical Decision Support." Annals of Pharmacotherapy 53, no. 1 (2018): 35–42. http://dx.doi.org/10.1177/1060028018788688.

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Background: Indication-specific medication dosing support is needed to improve pediatric dosing support. Objective: To compare the sensitivity and positive predictive value (PPV) of different meningitis dosing alert triggers and dosing error rates between antimicrobials with and without meningitis order sentences. Methods: We retrospectively analyzed 4-months of pediatric orders for antimicrobials with meningitis-specific dosing. At the time of the order, it was determined if the antimicrobial was for meningitis management, if a cerebrospinal fluid (CSF) culture was ordered, and if a natural l
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B. Kadam, Ashok, and Sanjay A. Kamble. "Exploring the Bioactivity of Plectranthus species: A Sustainable Solution to Antimicrobial Resistance." International Journal of Current Microbiology and Applied Sciences 14, no. 2 (2025): 26–34. https://doi.org/10.20546/ijcmas.2025.1402.003.

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The escalating antimicrobial resistance (AMR) crisis necessitates innovative and sustainable solutions to address resistant pathogens. This study investigates the antimicrobial potential of five Plectranthus species: Plectranthus prostratus, Plectranthus scutellarioides, Plectranthus barbatus, Plectranthus amboinicus, and Plectranthus caninus. Methanolic extracts of these species were assessed for antibacterial activity against Escherichia coli, Bacillus subtilis, and Salmonella Typhi using the agar well diffusion method. The results demonstrated significant dose-dependent inhibition, with P.
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Moon, Kyung, and Susan Gottesman. "A PhoQ/P-regulated small RNA regulates sensitivity of Escherichia coli to antimicrobial peptides." Molecular Microbiology 74, no. 6 (2009): 1314–30. http://dx.doi.org/10.1111/j.1365-2958.2009.06944.x.

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Nishijima, S., I. Kurokawa, and S. Kawabata. "Sensitivity of Propionibacterium acnes Isolated from Acne Patients: Comparative Study of Antimicrobial Agents." Journal of International Medical Research 24, no. 6 (1996): 473–77. http://dx.doi.org/10.1177/030006059602400604.

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The antimicrobial susceptibility of Propionibacterium acnes isolated before and after treatment of acne patients was measured. The four female and three male acne patients were treated with an oral acne medication, roxithromycin or minocycline, and/or a topical acne medication, nadifloxacin cream or clindamycin hydrochloride lotion for 1 – 8 weeks. The isolated strains were tested for their susceptibility to the antimicrobial action of: nadifloxacin, ofloxacin, erythromycin, clindamycin hydrochloride, tetracycline hydrochloride, minocycline, doxycycline, ampicillin, cephalexin and gentamycin.
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Flor-de-Lima, Filipa, Tânia Martins, Ana Teixeira, Helena Pinto, Edgar Botelho-Moniz, and Alberto Caldas-Afonso. "Etiological Agents and Antimicrobial Susceptibility in Hospitalized Children with Acute Pyelonephritis." Acta Médica Portuguesa 28, no. 1 (2015): 15. http://dx.doi.org/10.20344/amp.5033.

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<strong>Introduction:</strong> Antibiotic resistance driven by antibiotic use remains a major public health and professional concern. Our aim was to know the local prevalence of uropathogens and their antimicrobial susceptibility profile in acute pyelonephritis.<br /><strong>Material and Methods:</strong> A prospective study of patients admitted in a level III Pediatric Department ward with acute pyelonephritis from 1994 to 2012 was performed in Northern Portugal. Etiological agents and their antimicrobial sensitivity profile were evaluated in four timed periods (
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de Souza, Paula Araujo, Milena Cristina Silva dos Santos, Rebeca Vitória da Silva Lage de Miranda, et al. "Evaluation of Antimicrobial Resistance Patterns of Pseudomonas aeruginosa Strains Isolated among COVID-19 Patients in Brazil Typed by Fourier-Transform Infrared Spectroscopy." Life 14, no. 9 (2024): 1079. http://dx.doi.org/10.3390/life14091079.

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This study aimed to characterize Pseudomonas aeruginosa strains isolated from hospitalized patients during the COVID-19 pandemic. This was achieved using phenotypic and molecular techniques, including their antimicrobial resistance profile and biofilm formation. Eighteen strains were isolated from a hospital in Rio de Janeiro, Brazil, and identified by VITEK®2, MALDI-TOF/MS (VITEK MS® and MALDI Biotyper®), and 16S rRNA sequencing. Fourier-transform infrared (FTIR) spectroscopy, antimicrobial susceptibility testing, and biofilm formation and disinfectant tolerance tests were applied to evaluate
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Sayin Kutlu, Selda, Zafer Aybek, Koray Tekin, et al. "Is short course of antimicrobial therapy for asymptomatic bacteriuria before urologic surgical procedures sufficient?" Journal of Infection in Developing Countries 6, no. 02 (2011): 143–47. http://dx.doi.org/10.3855/jidc.1781.

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Introduction: Duration of treatment of asymptomatic bacteriuria for patients undergoing urologic surgical procedures is undetermined. We compared the efficacy of long- versus short-course antimicrobial treatment in patients with asymptomatic bacteriuria undergoing urologic surgical procedures. Methodology: Patients were divided into two groups according to duration of antimicrobial treatment. Group A patients received a single dose of an appropriate antibiotic, determined by antimicrobial sensitivity testing, 30 to 60 minutes before the surgical procedure. If a urinary catheter was placed post
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AL-Sabagh, Fadi S. H., Kais K. Ghaima, and Alhan H. Sh.AL-Dabbagh. "The antibacterial activity of LL-37 peptide against multidrug-resistant Pseudomonas aeruginosa isolated from burn infections." Bionatura 8, no. 1 (2023): 1–5. http://dx.doi.org/10.21931/rb/2023.08.01.69.

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Multidrug-resistant Pseudomonas aeruginosa has emerged as a significant problem worldwide, posing a severe hazard to burn-infected patients. Antimicrobial peptides produced from humans or animals and synthetic peptides have received interest as antibiotic options for treating resistant bacteria, particularly those obtained from burn patients. The current work evaluated the role of antimicrobial peptide LL-37 as an antibacterial agent against multidrug P. aeruginosa isolates from burn infections. The study samples were collected between November 2021 and the end of February 2022 and included 15
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Maesum Ali, Saleh Khurshied, Altaf Hussain, Muhammad Ali, and Ali Khurshid. "Comparison of Current Bacteriological Profile and Antibiotic Sensitivity Pattern in Tubotympanic Type of Chronic Suppurative Otitis Meida between Adult and Pediatric Patients Presenting at Tertiary Care Hospital in Islamabad Pakistan." Indus Journal of Bioscience Research 3, no. 5 (2025): 613–17. https://doi.org/10.70749/ijbr.v3i5.1353.

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Background: CSOM, in its tubotympanic variety, continues to be one of the most common causes of a preventable cause of a hearing loss in developing countries, among both children and adults. Appreciating the prevailing bacteriological trends as well as antibiotic sensitivity patterns is crucial to the intervention as an increasing antimicrobial resistance loom over the horizon. Aim: To compare the present bacteriology and sensitivity of the antibiotics of adult and pediatric cases of tubotympanic type of CSOM attending a tertiary care hospital in Islamabad Pakistan. Methods: This comparative c
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Sohaib, Muhammad, Dildar Hussain Kalhoro, Hasina Baloch, et al. "Antimicrobial Sensitivity of Bacterial Pathogens Isolated from Poultry Feed, Water, and Eggshell." Journal of Microbiological Sciences 2, no. 01 (2023): 1–7. http://dx.doi.org/10.38211/jms.2023.01.46.

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Poultry is the most important source of proteins forconsumption. Egg shell and drinking water contributes significantly to the spread of viral, bacterial, and protozoan infections in poultry. A total of 150 samples from poultry feed (feeders n=25, feed bags n=25), water (water tanks n=25, drinkers n=25), and eggshell (n=50) were collected from ten layer farms of district Tando Allahyar. Overall results showed that higher 52% bacterial infection was recorded from the poultry feed, 42% was recorded from water samples while the lowest prevalence recorded from the eggshell 32%. The isolated bacter
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Yap, Aaron, Sharmini Muttaiyah, Sarah Welch, and Rachael L. Niederer. "Role of Antimicrobial Resistance in Outcomes of Acute Endophthalmitis." Antibiotics 12, no. 8 (2023): 1246. http://dx.doi.org/10.3390/antibiotics12081246.

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Background: This study explores local trends in antimicrobial resistance and its influence on long-term visual outcomes following treatment with broad-spectrum empiric intravitreal antibiotics. Methods: All patients undergoing intraocular sampling for endophthalmitis from Auckland between January 2006–May 2023 were included. The impact of antimicrobial resistance on the final visual outcome was analysed using logistic regression models. Results: 389 cases of endophthalmitis were included, and 207 eyes (53.2%) were culture positive. When tested, all Gram-positive microorganisms were fully susce
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Kornoukhova, L. A., V. L. Emanuel, Yu V. Gurieva та I. G. Chernykh. "Effect of Differences in the CLSI and EUCAST Criteria on the Interpretation of Enterobacteriaceae Sensitivity to Carbapenems". Antibiotics and Chemotherapy 66, № 7-8 (2021): 30–37. http://dx.doi.org/10.37489/0235-2990-2021-66-7-8-30-37.

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Relevance: The two systems for determining the susceptibility of bacteria to antimicrobial drugs, CLSI and EUCAST, are recommended for use in the global system of epidemiological surveillance of antimicrobial resistance of the World Health Organization. However, they differ in the methodology of setting an antimicrobial susceptibility testing, threshold values of cut-off points, as well as interpretation of results. The true significance of methodological differences between these systems for global microbiological monitoring is unclear.The aim of the study was to evaluate the influence of differenc
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Popova, T. P., and I. Ignatov. "In vitro antimicrobial activity of colloidal nano silver." BULGARIAN JOURNAL OF VETERINARY MEDICINE 26, no. 2 (2023): 168–81. http://dx.doi.org/10.15547/bjvm.2411.

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The antimicrobial effect of colloidal nanosilver (AgNPs) at concentrations of 20 and 30 ppm against reference Esherichia coli, Salmonella enterica, Staphylococcus aureus, Clostridium perfringens, Candida albicans strains and two clinical isolates (Pseudominas aeruginosa and Streptococcus pyogenes) was tested. The classical agar diffusion method, determination of the minimum inhibitory concentrations (MIC) and the time of antimicrobial action of AgNPs were used. In the studies performed by the agar diffusion method, a very good inhibitory effect of AgNPs 30 ppm and to a much lesser extent of Ag
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Oyekanmi, B. A., I. B. Osho, and J. C. Kolawole. "Antimicrobial, phytochemical and pharmacological properties of Phyllanthus niruri linn." Research Journal of Health Sciences 11, no. 2 (2023): 108–18. http://dx.doi.org/10.4314/rejhs.v11i2.4.

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Introduction: Phyllanthus niruri is a common herb widely used in home remedies against infectious agents. This study unveils the antimicrobial and therapeutic potentials of P. niruri against Escherichia coli infection.Methods: Ethanol and water extracts of the plant were prepared and investigated for their antimicrobial activity using the agar well diffusion method against eleven clinical isolates. The in vivo study was conducted on albino rats, infected and subsequently treated.Results: The observation showed Ciprofloxacin with the highest (41 mm) sensitivity against P. mirabilis; and lowest
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ONUORAH, STELLA I., ABIODUN A. ADESIYUN, and JAMES O. ADEKEYE. "In vitro Antibiotic Sensitivity of Staphylococcus aureus Strains Isolated from a Nigerian Fermented Cereal Drink." Journal of Food Protection 50, no. 11 (1987): 956–58. http://dx.doi.org/10.4315/0362-028x-50.11.956.

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The sensitivity of 253 Staphylococcus aureus strains isolated from a Nigerian locally-fermented cereal drink (kunun zaki) to 11 antimicrobial agents was determined. Two hundred and forty-seven (97.6%) strains were resistant to one or more of the antimicrobial agents and only 4 (1.6%) isolates were sensitive to all of the agents. Of the isolates from the kunun zaki preparation, 97.8% were resistant while 98.6% from kunun zaki bought at sale outlet and 96.7% of those isolated from utensils were resistant. There was no significant difference in resistance of isolates from the sources (P>0.
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Đorđević, Z., S. Milinić, R. Stolić, and N. Đonović. "THE MOST COMMON PATHOGENS OF BACTERIEMIA AND THEIR RESISTANCE IN HOSPITALIZED PATIENTS." Praxis medica 37, no. 2 (2009): 103–8. http://dx.doi.org/10.70949/pramed200902305dj.

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<p>To show the most common causes of bacteriemia in hospitalized patients, as well as their sensitivity to antimicrobial agents. The research data were extracted from official reports produced by Microbiological Laboratory in Clinical Centre Kragujevac. Isolation and identification of the causes were performed with standard microbiological methodology. Sensitivity to antimicrobial medication was tested using disc diffusion. Interpretation and inhibition zones of antibiogram were done in accordance with guidelines of US Clinical and Laboratory Standards Institute (CLSI). A descrip
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Navapurkar, Vilas, Josefin Bartholdson Scott, Mailis Maes, et al. "Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia." Wellcome Open Research 6 (October 12, 2022): 256. http://dx.doi.org/10.12688/wellcomeopenres.17099.3.

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Background: The diagnosis of pneumonia has been hampered by a reliance on bacterial cultures which take several days to return a result, and are frequently negative. In critically ill patients this leads to the use of empiric, broad-spectrum antimicrobials and compromises good antimicrobial stewardship. The objective of this study was to establish the performance of a syndromic molecular diagnostic approach, using a custom TaqMan array card (TAC) covering 52 respiratory pathogens, and assess its impact on antimicrobial prescribing. Methods: The TAC was validated against a retrospective multi-c
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Navapurkar, Vilas, Josefin Bartholdson Scott, Mailis Maes, et al. "Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia." Wellcome Open Research 6 (May 10, 2022): 256. http://dx.doi.org/10.12688/wellcomeopenres.17099.2.

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Background: The diagnosis of pneumonia has been hampered by a reliance on bacterial cultures which take several days to return a result, and are frequently negative. In critically ill patients this leads to the use of empiric, broad-spectrum antimicrobials and compromises good antimicrobial stewardship. The objective of this study was to establish the performance of a syndromic molecular diagnostic approach, using a custom TaqMan array card (TAC) covering 52 respiratory pathogens, and assess its impact on antimicrobial prescribing. Methods: The TAC was validated against a retrospective multi-c
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Navapurkar, Vilas, Josefin Bartholdson Scott, Mailis Maes, et al. "Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia." Wellcome Open Research 6 (October 11, 2021): 256. http://dx.doi.org/10.12688/wellcomeopenres.17099.1.

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Background: The diagnosis of pneumonia has been hampered by a reliance on bacterial cultures which take several days to return a result, and are frequently negative. In critically ill patients this leads to the use of empiric, broad-spectrum antimicrobials and compromises good antimicrobial stewardship. The objective of this study was to establish the performance of a syndromic molecular diagnostic approach, using a custom TaqMan array card (TAC) covering 52 respiratory pathogens, and assess its impact on antimicrobial prescribing. Methods: The TAC was validated against a retrospective multi-c
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Thi My Hanh, TRUONG, NGUYEN Thi Hanh, LE Thi May, TRUONG Thi Thanh Vinh, and DANG Thi Lua. "ANTIMICROBIAL RESISTANCE IN Streptococcus agalactiae IN TILAPIA (Oreochromis sp.) FARMING IN NORTHERN VIETNAM." Vinh University Journal of Science 53, no. 2A (2024): 15–23. http://dx.doi.org/10.56824/vujs.2023a157.

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Antimicrobial resistance (AMR) is a threat to animal and human health globally. Antimicrobials are used in aquaculture to control different bacterial diseases. However, inappropriate use of antimicrobials can accelerate the emergence of AMR. This study was conducted to determine antimicrobial resistance in Streptococcus agalactiae, which affects and causes diseases with high mortality in tilapia. A total of 26 S. agalactiae isolates were streaked from kidney/brain/liver samples of diseased farmed tilapia from 2017 to 2021 at Hai Duong, Bac Ninh, Hoa Binh, Yen Bai provinces. The sensitivity of
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Singh, Bhoj R., Dharmendra K. Sinha, Vinodh K. OR, et al. "Antimicrobial Activity of Agarwood Oil Against Multiple-Drug-Resistant (MDR) Microbes of Clinical, Food and Environmental Origin." Current Drug Discovery Technologies 17, no. 3 (2020): 348–56. http://dx.doi.org/10.2174/1570163816666190125163536.

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Background and Objectives: Multiple-Drug-Resistance (MDR) among bacteria is an imminent problem and alternative therapies are seen as a future abode. Agarwood Oil (AO) is described to possess antimicrobial activity besides many other medicinal utilities. This paper discusses the antimicrobial activity of AO on MDR and non-MDR strains of microbes of 69 genera isolated from clinical and non-clinical samples. Methods and Results: In this study sensitivity of microbes was determined for conventional antimicrobials and AO using disc diffusion assay followed by determination of minimum inhibitory co
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Sebbar, G., K. Zro, K. Id Sidi Yahia, M. Elouennass, A. Filali-Maltouf, and B. Belkadi. "Antimicrobial susceptibility screening test of Mannheimia haemolytica and Pasteurella multocida (serogroup A) Moroccan strains isolated from ruminants." BULGARIAN JOURNAL OF VETERINARY MEDICINE 25, no. 1 (2022): 161–65. http://dx.doi.org/10.15547/bjvm.2019-0109.

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The present study is the first report aimed to determine the antibiotic susceptibility profiles of Mannheimia haemolytica and Pasteurella multocida serogroup A Moroccan isolates. Each isolate was tested for sensitivity to amoxicillin (A), amoxicillin/clavulanic acid (AMC), gentamicin (CN), streptomycin (STR), florfenicol (FFC), doxycycline (DO), erythromycin (E), spiramycin (SP), nalidixic acid (NA), flumequine (UB), enrofloxacin (ENF) and sulfamethoxazole (SXT). All isolates showed resistance to the antibiotics tested at a rate greater than 14%, except for one P. multocida isolate which had n
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Seetharam, D. S. "retrospective study of anti-microbial susceptibility pattern among bacterial strain isolated from cases of urinary tract infection." Journal of Medical Pharmaceutical and Allied Sciences 14, no. 3 (2025): 70–79. https://doi.org/10.55522/jmpas.v14i3.6792.

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Urinary Tract Infections (UTI) are common among the individuals and most prevalent bacterial infections seen in clinical practice. It has been observed that nosocomial infection was most common in many hospitals. The study findings shows the causative agents for UTI’s were antibiotics and they exhibit poor patterns of antimicrobial sensitivity. The Institute of Medical Science, Banaras Hindu University (IMS-BHU), which serves a large number of partially treated or maltreated patients, may have various etiological agents and sensitivity patterns. To investigate the range of bacterial infections
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Diaz Dilernia, Fernando, David Watson, David Heinrichs, and Edward Vasarhelyi. "The antimicrobial properties of exogenous copper in human synovial fluid against Staphylococcus aureus." Bone & Joint Research 13, no. 11 (2024): 632–46. http://dx.doi.org/10.1302/2046-3758.1311.bjr-2024-0148.r1.

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AimsThe mechanism by which synovial fluid (SF) kills bacteria has not yet been elucidated, and a better understanding is needed. We sought to analyze the antimicrobial properties of exogenous copper in human SF against Staphylococcus aureus.MethodsWe performed in vitro growth and viability assays to determine the capability of S. aureus to survive in SF with the addition of 10 µM of copper. We determined the minimum bactericidal concentration of copper (MBC-Cu) and evaluated its sensitivity to killing, comparing wild type (WT) and CopAZB-deficient USA300 strains.ResultsUAMS-1 demonstrated a gr
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Ahmed Hamdy Badr, Mohamed Sherif, Ahmed Abdelaziz Sayed, and Mostafa Mohamed Elnakib. "Effects of extremely low-frequency electromagnetic fields on the susceptibility and resistance mechanisms of multi-drug resistant Pseudomonas aeruginosa." GSC Advanced Research and Reviews 12, no. 1 (2022): 091–100. http://dx.doi.org/10.30574/gscarr.2022.12.1.0187.

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The purpose of this study is to assess the impact of low-frequency electromagnetic fields (LF-EMFs = 0.5 MHz) on the phenotypic and genotypic levels concerning the antibiotic resistance, antimicrobial-resistant (AMR) genes, and resistance mechanisms of Pseudomonas aeruginosa (P. aeruginosa). In this study, the bacterial isolates were exposed to 0.5 MHz and then inoculated to a new medium for the assessment of their antibiotic sensitivity. The results showed that there were statistically significant changes in the antibiotic sensitivity upon exposure to extremely low-frequency waves along with
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