Relevant bibliographies by topics / Antimycobacterial Susceptibility Using BACTEC

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Academic literature on the topic 'Antimycobacterial Susceptibility Using BACTEC'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Antimycobacterial Susceptibility Using BACTEC"

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Hannan, Abdul, Saira Munir, Muhammad Usman Arshad, and Nabila Bashir. "In Vitro Antimycobacterial Activity of Pakistani Beri Honey Using BACTEC MGIT 960." International Scholarly Research Notices 2014 (October 7, 2014): 1–4. http://dx.doi.org/10.1155/2014/490589.

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Background. Tuberculosis (TB) is a chronic bacterial disease. Mycobacterium tuberculosis, being the leading member of the MTB complex, is the main cause of tuberculosis worldwide. Tuberculosis is managed with combination of drugs: streptomycin, isoniazid, rifampicin, ethambutol, and pyrazinamide. Over the recent past years resistance against first line antituberculous drugs has emerged rapidly throughout the world resulting in MDR strains. The new threat in the management of MDR-TB is the development of resistance against second line drugs: aminoglycosides, polypeptides, fluoroquinolones, and
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Moore, Andrea V., Scott M. Kirk, Steven M. Callister, Gerald H. Mazurek, and Ronald F. Schell. "Safe Determination of Susceptibility of Mycobacterium tuberculosis to Antimycobacterial Agents by Flow Cytometry." Journal of Clinical Microbiology 37, no. 3 (1999): 479–83. http://dx.doi.org/10.1128/jcm.37.3.479-483.1999.

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We showed previously that susceptibility testing forMycobacterium tuberculosis labeled with fluorescein diacetate could be accomplished rapidly by using flow cytometry. However, safety was a major concern because mycobacteria were not killed prior to flow cytometric analysis. In this study, we developed a biologically safe flow cytometric susceptibility test that depends on detection and enumeration of actively growing M. tuberculosis organisms in drug-free and antimycobacterial agent-containing medium. The susceptibilities of 17 clinical isolates of M. tuberculosis to ethambutol, isoniazid, a
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Bergmann, John S., Geoffrey Fish, and Gail L. Woods. "Evaluation of the BBL MGIT (Mycobacterial Growth Indicator Tube) AST SIRE System for Antimycobacterial Susceptibility Testing of Mycobacterium tuberculosis to 4 Primary Antituberculous Drugs." Archives of Pathology & Laboratory Medicine 124, no. 1 (2000): 82–86. http://dx.doi.org/10.5858/2000-124-0082-eotbmm.

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Abstract Objective.—To evaluate the performance of the BBL MGIT (Mycobacterial Growth Indicator Tube) AST SIRE system for the antimycobacterial susceptibility testing of Mycobacterium tuberculosis to isoniazid (at a concentration equivalent to the lower concentration used for testing by the method of proportion), rifampin, ethambutol, and streptomycin. Design.—Thirty-one clinical isolates and 30 challenge strains provided by the Centers for Disease Control and Prevention (CDC) were tested by MGIT AST SIRE using 2 methods of inoculum preparation, and results were compared with those of the meth
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Zhurilo, A. A., A. I. Barbova, Yu A. Cherednik, et al. "COMPARISON OF GENEXPERT MTB/RIF AND GENOTYPE SYSTEMS WITH MTBDRPLUS STRIPS FOR DETECTION OF MUTATIONS THAT ARE ASSOCIATED WITH M. TUBERCULOSIS RESISTANCE TO RIFAMPICIN IN TUBERCULOSIS." Ukrainian Pulmonology Journal 30, no. 4 (2022): 34–41. http://dx.doi.org/10.31215/2306-4927-2022-30-4-34-41.

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COMPARISON OF GENEXPERT MTB/RIF AND GENOTYPE SYSTEMS WITH MTBDRPLUS STRIPS FOR DETECTION OF MUTATIONS, ASSOCIATED WITH M. TUBERCULOSIS RESISTANCE TO RIFAMPICIN IN TUBERCULOSIS A. A. Zhurilo, A. I. Barbova, Yu. A. Cherednik, P. S. Trofi mova, S. V. Mironchenko, O. V. Pavlova, A. V. Chernov, L. M. Sladkova Summary The aim was to analyze the level of compliance of two molecular genetic methods GeneXpert MTB/RIF and GenoTypeDRplus in determining the drug resistance of M. tuberculosis to rifampicin when detecting mutations in the RRDR region associated with drug resistance. Object and methods. We s
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Sakhelashvili, M. I., Z. I. Piskur, O. I. Sakhelashvili­–Bil, et al. "Application of BI-V for contact children and adolescents from focies of multidrug-resistant tuberculous infection: evaluation of effectiveness." Tuberculosis, Lung Diseases, HIV Infection, no. 1 (March 15, 2023): 37–43. http://dx.doi.org/10.30978/tb-2023-1-37.

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Objective — to study the need of using the natural immunomodulator ВІ-V for contact children and adolescents from focies of multidrug-resistant tuberculous infection (MDR-TBI) for a non-specific immunoprevention of tuberculosis (TB). Materials and methods. A retrospective analysis of the medical records of 120 contacts (75 children and 45 adolescents) from focies of MDR-TBI and 102 adult with TB, who became the source of infection was carried out. Microbiological examination in adults included the detection of Mycobacterium tuberculosis (MBT) in sputum by smear microscopy, sowing of material o
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Sriram, D., K. Jyothi Mallika, and P. Yogeeswari. "Synthesis of Tetrahydro-2H-[1,3,5]thiadiazine-5-(4-pyridylcarboxamido)-2-thione with antitubercular activity." Scientia Pharmaceutica 72, no. 1 (2004): 35–41. http://dx.doi.org/10.3797/scipharm.aut-04-04.

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3-Substituted-5-(4-pyridylcarboxamide)tetrahydro-2H-[1,3,5]thiadizine-2-thione derivatives (1-9) were synthesized as derivatives of isoniazid (INH) to overcome the resistance developed with its therapeutic use. The structures were confirmed by their spectral and elemental analyses data. These derivatives revealed higher lipophilicity compared with INH. The antimycobacterial activity of the synthesized compounds and INH was evaluated in vitro against Mycobacterium tuberculosis H37Rv at 6.25 µg/ml in BACTEC 12B medium using the BACTEC 460 radiometric system. The derivatives exhibited antitubercu
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Collins, L. A., M. N. Torrero, and S. G. Franzblau. "Green Fluorescent Protein Reporter Microplate Assay for High-Throughput Screening of Compounds againstMycobacterium tuberculosis." Antimicrobial Agents and Chemotherapy 42, no. 2 (1998): 344–47. http://dx.doi.org/10.1128/aac.42.2.344.

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ABSTRACT An optimal assay for high-throughput screening for new antituberculosis agents would combine the microplate format and low cost of firefly luciferase reporter assays and redox dyes with the ease of kinetic monitoring inherent in the BACTEC system. The green fluorescent protein (GFP) of the jellyfish Aequorea victoria is a useful reporter molecule which requires neither substrates nor cofactors due to the intrinsically fluorescent nature of the protein. The gene encoding a red-shifted, higher-intensity GFP variant was introduced by electroporation into Mycobacterium tuberculosis H37Ra
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Arain, T. M., A. E. Resconi, M. J. Hickey, and C. K. Stover. "Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery." Antimicrobial Agents and Chemotherapy 40, no. 6 (1996): 1536–41. http://dx.doi.org/10.1128/aac.40.6.1536.

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Bioluminescence-based assays to indicate antimicrobial susceptibility have been developed and validated for recombinant strains of Mycobacterium tuberculosis, Mycobacterium bovis BCG, Mycobacterium avium, and Mycobacterium intracellulare expressing an integrated eukaryotic luciferase gene. MICs determined with these bioluminescence assays for several antimycobacterial agents, including isoniazid, ethambutol, rifampin, amikacin, streptomycin, ciprofloxacin, and clarithromycin, compared favorably with traditional BACTEC methods and visual estimations of the inhibitory end point. Assay methodolog
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Werngren, J., E. Sturegård, P. Juréen, K. Ängeby, S. Hoffner, and T. Schön. "Reevaluation of the Critical Concentration for Drug Susceptibility Testing of Mycobacterium tuberculosis against Pyrazinamide Using Wild-Type MIC Distributions andpncAGene Sequencing." Antimicrobial Agents and Chemotherapy 56, no. 3 (2011): 1253–57. http://dx.doi.org/10.1128/aac.05894-11.

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ABSTRACTPyrazinamide (PZA) is a potent first-line agent for the treatment of tuberculosis (TB) with activity also against a significant part of drug-resistantMycobacterium tuberculosisstrains. Since PZA is active only at acid pH, testing for susceptibility to PZA is difficult and insufficiently reproducible. The recommended critical concentration for PZA susceptibility (MIC, 100 mg/liter) used in the Bactec systems (460 and MGIT 960) has not been critically evaluated against wild-type MIC distributions in clinical isolates ofMycobacterium tuberculosis. Using the Bactec MGIT 960 system, we dete
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Piersimoni, Claudio, Domenico Nista, Stefano Bornigia, and Giuseppina De Sio. "Evaluation of a New Method for Rapid Drug Susceptibility Testing of Mycobacterium avium Complex Isolates by Using the Mycobacteria Growth Indicator Tube." Journal of Clinical Microbiology 36, no. 1 (1998): 64–67. http://dx.doi.org/10.1128/jcm.36.1.64-67.1998.

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The reliability of the Mycobacteria Growth Indicator Tube (MGIT [BBL]) for rapid drug susceptibility testing of Mycobacterium avium complex (MAC) isolates was evaluated. MICs of amikacin, clarithromycin, clofazimine, ethambutol, and rifabutin were determined by the MGIT system for 16 MAC strains. The results were compared with those obtained by the BACTEC broth macrodilution method. The turnaround times were 6 to 8 days (median, 7 days) for the MGIT and 5 to 7 days (median, 6 days) for the BACTEC system. Agreements with BACTEC system-determined MICs, within ±1 log2 dilution, were 100, 100, 88,
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Dissertations / Theses on the topic "Antimycobacterial Susceptibility Using BACTEC"

1

DeCoster, David J. "Comparison of the BACTEC TB-460 system, flow cytometric susceptibility assay and proportion method for susceptibility of mycobacterium tuberculosis to antimycobacterial agents." 2004. http://catalog.hathitrust.org/api/volumes/oclc/56190530.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 2004.<br>Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 20-25).
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