Relevant bibliographies by topics / Antioxidant activities

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Antioxidant activities'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 May 2024

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Journal articles on the topic "Antioxidant activities"

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Martic, Sanela. "Phenolic Antioxidants: Redox Properties and Antioxidant Activities." ECS Meeting Abstracts MA2020-01, no. 43 (May 1, 2020): 2497. http://dx.doi.org/10.1149/ma2020-01432497mtgabs.

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Hou, J. P., H. Wu, Y. Wang, and X. C. Weng. "Isolation of some compounds from nutmeg and their antioxidant activities." Czech Journal of Food Sciences 30, No. 2 (March 9, 2012): 164–70. http://dx.doi.org/10.17221/509/2010-cjfs.

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Six compounds, licarin-B (1), dehydrodiisoeugenol (2), malabaricone B (3), malabaricone C (4), &beta;-sitosterol (5), and daucosterol (6) were isolated from the seed (nutmeg) of Myristica fragrans Houtt and identified. Among them, malabaricone B was identified for the first time in nutmeg. Antioxidant activities of the isolated compounds were studied using oil stability index (OSI), reducing power, ABTS<sup>●+</sup> scavenging, and DPPH<sup>●</sup> scavenging methods. The results showed that Malabaricone C is an efficient antioxidant agent which exhibits a stronger antioxidant activity than the commonly used synthetic antioxidants in all studied methods. This compound may have a potential to be used as a natural antioxidant in food.
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Kancheva, V. D., L. Saso, S. E. Angelova, M. C. Foti, A. Slavova-Kasakova, C. Daquino, V. Enchev, O. Firuzi, and J. Nechev. "Antiradical and antioxidant activities of new bio-antioxidants." Biochimie 94, no. 2 (February 2012): 403–15. http://dx.doi.org/10.1016/j.biochi.2011.08.008.

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Liu, Qing, Guo-Yi Tang, Cai-Ning Zhao, Xiao-Ling Feng, Xiao-Yu Xu, Shi-Yu Cao, Xiao Meng, Sha Li, Ren-You Gan, and Hua-Bin Li. "Comparison of Antioxidant Activities of Different Grape Varieties." Molecules 23, no. 10 (September 23, 2018): 2432. http://dx.doi.org/10.3390/molecules23102432.

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Grapes are widely consumed in the world, and different grape varieties could exhibit distinctly different antioxidant activities. In this study, the free radical-scavenging and antioxidant activities of lipophilic, hydrophilic, and insoluble-bound fractions from 30 grape varieties were evaluated by ferric-reducing antioxidant powers (FRAP), Trolox equivalent antioxidant capacities (TEAC), total phenolic contents (TPC), and total flavonoid contents (TFC). The results indicated that the 30 grape varieties exhibited diverse FRAP values (1.289–11.767 μmol Fe(II)/g FW), TEAC values (0.339–4.839 μmol Trolox/g FW), TPC values (0.294–1.407 mg GAE/g FW) and TFC values (0.082–0.132 mg QE/g FW). Several grapes, such as Pearl Black Grape (Xinjiang), Summer Black Grape (Shaanxi), Pearl Green Grape (Xinjiang), Seedless Green Grape (Xinjiang), and Seedless Red Grape (Yunnan), exhibited strong free radical-scavenging and antioxidant activities, which could be consumed as good sources of natural antioxidants to prevent several diseases induced by oxidative stress, such as cardiovascular disease and cancer. Furthermore, several antioxidants were identified and quantified, including caffeic acid, catechin gallate, epicatechin, gallic acid, protocatechuic acid and rutin, which could contribute to the antioxidant activities of grapes.
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Somsila, Pimchanok, Uthai Sakee, Akeapot Srifa, and Watchara Kanchanarach. "Antioxidant and Antimicrobial Activities of Polycephalomyces nipponicus." Journal of Pure and Applied Microbiology 12, no. 2 (June 30, 2018): 567–76. http://dx.doi.org/10.22207/jpam.12.2.15.

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Ohkatsu, Yasukazu, Sachiko Kubota, and Takuma Sato. "Antioxidant and Photo-antioxidant Activities of Phenylpropanoids." Journal of the Japan Petroleum Institute 51, no. 6 (2008): 348–55. http://dx.doi.org/10.1627/jpi.51.348.

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Xu, Qing, Tian Zhong, and Hui Li Li. "Antioxidant and Free Radical Scavenging Activities of N-Modified Chitosans." Advanced Materials Research 1002 (August 2014): 91–98. http://dx.doi.org/10.4028/www.scientific.net/amr.1002.91.

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Recently, the search for effective natural antioxidants use in food and medicinal fields to replace synthetic ones has attracted the most attention. Chitosan, a natural nontoxic biopolymer, is known to possess antioxidant property, which is attributed that NH2 and OH attached in the pyranose ring react with unstable free radicals to form stable macromolecule radicals. It has been observed that the antioxidant activity of chitosan is closely related to the form of nitrogen atom in the molecules. This review focuses on the antioxidant and free radical scavenging activities of various nitrogen atom of chitosan, including N-acylated chitosans, Schiff bases of chitosan, N-alkyl chitosan, and N-quaternized chitosan. The free radical scavenging mechanisms are summarized and the effects on free radical scavenging activity of N-modified chitosan are discussed. This work may provide more insights into the antioxidant ability of N-modified chitosans and potentially enable them to be used as natural antioxidants for application in food, agriculture, cosmetic and biomedical science. Keywords: N-modified chitosan, Sythesis, Antioxidant, Free radical scavenging
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FUJIMOTO, Kenshiro, Hiroko OHMURA, and Takashi KANEDA. "Biological antioxidant activities of bromophenols and certain other antioxidants." Agricultural and Biological Chemistry 50, no. 1 (1986): 101–8. http://dx.doi.org/10.1271/bbb1961.50.101.

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Fujimoto, Kenshiro, Hiroko Ohmura, and Takashi Kaneda. "Biological Antioxidant Activities of Bromophenols and Certain Other Antioxidants." Agricultural and Biological Chemistry 50, no. 1 (January 1986): 101–8. http://dx.doi.org/10.1080/00021369.1986.10867342.

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Lee, Choon Young, Ajit Sharma, Julius Semenya, Charles Anamoah, Kelli N. Chapman, and Veronica Barone. "Computational Study of Ortho-Substituent Effects on Antioxidant Activities of Phenolic Dendritic Antioxidants." Antioxidants 9, no. 3 (February 25, 2020): 189. http://dx.doi.org/10.3390/antiox9030189.

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Antioxidants are an important component of our ability to combat free radicals, an excess of which leads to oxidative stress that is related to aging and numerous human diseases. Oxidative damage also shortens the shelf-life of foods and other commodities. Understanding the structure–activity relationship of antioxidants and their mechanisms of action is important for designing more potent antioxidants for potential use as therapeutic agents as well as preservatives. We report the first computational study on the electronic effects of ortho-substituents in dendritic tri-phenolic antioxidants, comprising a common phenol moiety and two other phenol units with electron-donating or electron-withdrawing substituents. Among the three proposed antioxidant mechanisms, sequential proton loss electron transfer (SPLET) was found to be the preferred mechanism in methanol for the dendritic antioxidants based on calculations using Gaussian 16. We then computed the total enthalpy values by cumulatively running SPLET for all three rings to estimate electronic effects of substituents on overall antioxidant activity of each dendritic antioxidant and establish their structure–activity relationships. Our results show that the electron-donating o-OCH3 group has a beneficial effect while the electron-withdrawing o-NO2 group has a negative effect on the antioxidant activity of the dendritic antioxidant. The o-Br and o-Cl groups did not show any appreciable effects. These results indicate that electron-donating groups such as o-methoxy are useful for designing potent dendritic antioxidants while the nitro and halogens do not add value to the radical scavenging antioxidant activity. We also found that the half-maximal inhibitory concentration (IC50) values of 2,2-diphenyl-1-picrylhydrazyl (DPPH) better correlate with the second step (electron transfer enthalpy, ETE) than the first step (proton affinity, PA) of the SPLET mechanism, implying that ETE is the better measure for estimating overall radical scavenging antioxidant activities.
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Dissertations / Theses on the topic "Antioxidant activities"

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McGinn, Jennifer Sarah. "The vasodilatory and antioxidant activities of polyphenolic substances." Thesis, University of Glasgow, 2002. http://theses.gla.ac.uk/1583/.

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This project was designed to determine the effect of a wide range of grape and tea based extracts and green tea catechins on vascular tension in vitro, further determine the relationship between their vasodilatory and antioxidant activities and identify the major polyphenols present in green and black tea. Grape and tea based extracts were examined for their vasodilator activity in vitro using standard organ bath pharmacology. All extracts evoked biphasic concentration-dependent relaxation in rabbit aortic vessels. Grape based extracts were significantly better vasodilators than tea based extracts. Previous work by others has shown that grape based products induce vascular relaxation via nitric oxide (NO) and endothelium-dependent mechanisms. This study demonstrated that a range of grape based extracts induced vasorelaxation responses via complex mechanisms including endothelium-dependent and independent mechanisms via vasodilating prostaglandins by way of prostacyclin and endothelial NO production. Tea based extracts on the other hand, induced vasorelaxation via the combined interactions of vasodilating endothelium-dependent prostaglandins. The relationship between the vasodilation capacity, antioxidant activity, based on the reduction of the free Fremy's radical and ferric reducing power, and total phenolic content of each extract was also determined. In general, a significant inverse correlation was identified between the vasodilator abilities of the grape and tea extracts in vitro and their antioxidants activities. This study demonstrates that grape and tea based extracts induce vasorelaxation in isolated rabbit aortic vessels and are effective antioxidants in vitro, within a concentration range that may be reached in vivo by moderate wine and tea consumption. The results presented here also indicate that consumption of green tea may have greater benefits than consumption of black tea in terms of their vasodilatory activity and antioxidant capacity in vitro.
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Jaishee, Nishika. "Phytochemical analysis of some ferns with reference to their antioxidant, hypoglycemic and antimicrobial activities." Thesis, University of North Bengal, 2016. http://ir.nbu.ac.in/hdl.handle.net/123456789/2747.

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Youdim, Kuresh Aaron. "Potential beneficial effects of thyme oil and thymol on aspects of ageing processes." Thesis, University of Strathclyde, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310179.

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Bonet, Sánchez Berta. "Antioxidant enzyme activities in fluvial biofilms as biomakers of metal pollution." Doctoral thesis, Universitat de Girona, 2013. http://hdl.handle.net/10803/110519.

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The present thesis aims to evaluate the use of antioxidant enzyme activities (AEA) of biofilm communities as biomarkers of metal pollution (mainly Zn) in fluvial ecosystems. In order to test AEA as biomarkers of metal pollution as well as their responses to environmental variables, several ecotoxicological experiments have been performed. A zoom from field studies (with high ecological realism) to microcosm experiments (under controlled conditions) has been done to fill the gap between both approaches and understand AEA responses under a multiple-stress (environmental and metallic) scenario. The field studies were carried out in the Riera d’Osor, a tributary of the Ter, located in the region of La Selva (Girona province)
L’objectiu d’aquesta tesi és avaluar l’ús de les activitats enzimàtiques antioxidants (AEA) dels biofilms com a biomarcadors de contaminació metàl·lica (principalment per zinc (Zn)) en els ecosistemes fluvials. Per tal d’estudiar la resposta de les AEA a la contaminació metàl•lica, així com també la resposta a altres canvis ambientals (situacions d’estrès múltiple), s’han realitzat diversos experiments ecotoxicològics fent un zoom des d’estudis de camp (amb un elevat realisme ecològic) fins a un estudi de laboratori utilitzant microcosmos (amb condicions controlades). Els estudis de camp s’han dut a terme a la riera d’Osor, afluent del Ter, situada a la comarca de la Selva (província de Girona)
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Sadi, Gokhan. "Antioxidant Enzyme Activities In Rat Liver Tissues Of Diabetic Rats." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/2/12605254/index.pdf.

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Free radicals are the compounds having one or more unpaired electrons in their outer orbital and this unpaired electron make these compounds very reactive. Especially as their concentration increases, they initiate a chain oxidation reaction of lipids, proteins and nucleic acids. The condition, in which the production of free radicals exceeds their elimination or tissue defense mechanism decrease against them or both occur together, is called oxidative stress. In diabetes mellitus which is a glucose metabolism disorder, there occurs excessive non-enzymatic protein oxidation, glucose autoxidation and enhanced activity of polyol pathway enzymes, which are the possible sources of the oxidative stress in this disease. In this study, the conditions of the activity measurements of major antioxidant enzymes, namely superoxide dismutase (SOD, EC 1.15.1.1), catalase (CAT, EC 1.11.1.6), glutathione peroxidase (GPx, 1.11.1.9) and glutathione S-transferase (GST, EC 2.5.1.18) were studied and the optimum conditions (pH, temperature and substrate concentrations) for each assay were determined. Further objectives of the study were to characterize the enzymatic antioxidant systems (catalase, superoxide dismutase, glutathione peroxidase and glutathione S-transferase), tissue oxidation status (concentrations of TBARS, protein carbonylation, and lipid/protein ratios) and nonenzymatic antioxidant (reduced glutathione) levels of the diabetic rat liver tissues. According to our results, the hepatic SOD and GPx activities significantly increased whereas CAT activity markedly decreased in diabetic rats compared to control group. Also, GST activities did not change in diabetes. As a result of oxidative stress, TBARS concentration, lipid/protein ratios and protein carbonylation increased and GSH levels decreased in diabetic rats compared to control rats. This increase in tissue damage, in spite of the increase in antioxidant enzyme activities, could have been due to the overproduction of reactive oxygen species that exceeded the capacity of the antioxidant enzymes during the eight week of diabetes.
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Talhi, Oualid. "Synthesis and biological activities of polyphenolic hybrids: evaluation of anti-cancer, anti-inflammatory and antioxidant activities." Doctoral thesis, Universidade de Aveiro, 2013. http://hdl.handle.net/10773/10132.

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Doutoramento em Química
Os compostos polifenólicos constituem uma classe de metabolitos secundários de plantas, mas existe também uma enorme quantidade de derivados sintéticos ou semi-sintéticos contendo múltiplas unidades fenólicas. Estes compostos apresentam importantes características biológicas, que dependem das suas estruturas básicas. Certos derivados desta família de compostos, tais como flavonoides, cromonas e cumarinas contribuem para os benefícios da dieta humana, e partilham o núcleo de benzopiran-(2 e 4)-ona ou benzofuran-3-ona. A presente dissertação inclui uma introdução geral e três capítulos que descrevem as novas rotas sintéticas estabelecidas para a preparação de novos híbridos de diversos compostos polifenólicos, assim como a sua elucidação estrutural e termina com a presentação dos resultados da avaliação biológica desses mesmos compostos. No segundo capítulo discute-se a preparação de híbridos de pirimidina- e imidazolidina-polifenóis, especialmente a síntese diastereoseletiva de novos híbridos benzofuran-3-ona-hidantoína e derivados de uracilo. A rota sintética envolve a ação de carbodiimidas sobre os ácidos cromona-(2- e 3)-carboxílicos num só passo ou em dois passos sequenciais, catalisada por uma base orgânica ou inorgânica. O terceiro capítulo descreve reações do tipo adições conjugadas 1,4 - hetero-ciclisações em cascata de compostos 1,3-dicarbonílicos em ácido cromona-3-carboxílico catalisadas por uma base orgânica, que originaram novas cromonas, cromanonas e flavonas polissubstituídas. As bispiranonas [bispiran-2 e 4)-onas] foram elaboradas numa reacção de acoplamento da 4-hidroxicumarina ou da lactona do ácido triacético com o ácido cromona-3-carboxílico ou precursores formil-funcionalizados (ω-formil-2’-hydroxy acetofenonas e cromona-3-carbaldeídos) utilizando organocatálise básica. Finalmente, alargou-se o estudo das adições conjugadas 1,4 para uma variedade de 4-hidroxipiran-2-onas e cetonas α,β-insaturadas para originar novos análogos de warfarina. Obteve-se uma variedade de estruturas complexas por hibridação das unidades de 4-hidroxicumarina ou da lactona do ácido triacético com os novos derivados de cromonas polissubstituídas. Todos as reações foram executadas em condições suaves e ambientalmente favoráveis, utilizando a 4-pirrolidinopiridina como organocatalisador básico. As estruturas dos novos híbridos polifenólicos foram caracterizados por técnicas espectroscópicas de alta resolução, incluindo espectroscopia de ressonância magnética nuclear (1D e 2D) e por difractometria de raios-X, que nos permitiram resolver o complexidade estrutural dos compostos sintetizados. O quarto capítulo apresenta os resultados da avaliação biológica obtidos com os híbridos polifenólicos sintetizados neste trabalho, mostrando a possibilidade de seu envolvimento na terapia do cancro. A maioria dos compostos foram avaliados quanto ao seu efeito sobre a citotoxicidade e proliferação de células leucémicas e ao seu envolvimento na regulação de via pró-inflamatória NF-kB, na qual, os híbridos de biscumarinas exibiram actividades elevadas (IC50 = 6-19 μM para inibição de NF-kB depois de 8 horas de incubação e IC50 = 15-39 μM para efeitos citotóxicos em células cancerosas, após 24 horas de incubação). Uma inibição moderada das enzimas HDAC e Cdc25 foi induzida pelos derivados de benzofuran-3-ona-hidantoína. Catorze dos novos derivados polifenólicos polissubstituídos, tendo como estrutura básica a benzopiran-4-ona, foram avaliados pela sua actividade quimiopreventiva do cancro mediada pela indução de sinalização citoprotectora Nrf2 (fator 2 relacionado com o fator nuclear da proteína E2) e capacidade para inibir a proliferação das células de cancro da mama. Os derivados da classe das cromanonas foram identificados como os indutores mais potentes da actividade Nrf2. As concentrações necessárias para aumentar a actividade de luciferase em 10 vezes (C10) foram de 2,8-21,3 μM. Todos os novos híbridos polifenólicos que apresentam atividade citotóxica e anti-proliferativa não afectam o crescimento de células saudáveis periféricas do sangue (PBMC) (IC50 > 50 μM), indicando a sua seletividade para as células cancerosas e sugerindo que alguns deles são estruturalmente interessantes para posteriores análises. A avaliação da atividade antioxidante utilizando os testes do radical livre DPPH e o poder redutor do ião férrico FRAP foram realizados em algumas estruturas híbridas polifenólicas.
Polyphenolic compounds represent a class of secondary metabolites of plants, but there are also a great number of synthetic or semi-synthetic derivatives characterized by the presence of multiples phenol moieties. Polyphenolic compounds underlie a number of biological characteristics such as the metabolic and therapeutic properties which depends on their basic phenolic structure. Certain members of this class, like flavonoids, chromones and coumarins contribute to the therapeutic benefits of the human diet, they all share the benzopyran-(2 or 4)-one or benzofuran-3-one nucleus. The present dissertation includes a general introduction and three main chapters describing the new synthetic methodologies established for the production of new polyphenolic hybrids, their fine structural elucidation and their biological application in cancer therapy involving redox-regulation and inflammation pathways The second chapter discusses the preparation of pyrimidine- and imidazolidine- based polyphenolic hybrids, especially the diastereoselective synthesis of new benzofuran-3-one-hydantoin hybrids and uracil derivatives. The organic synthetic route starts by the organic/inorganic base-catalyzed action of carbodiimides on chromone-(2 and 3)-carboxylic acids in a one-pot reaction or sequential steps. The third chapter describes the application of basic organocatalysis in the 1,4-conjugate additions / heterocyclisations tandem processes of 1,3-dicarbonyls on chromone-3-carboxylic acid leading to novel polysubstituted- chromones, chromanones and flavones. The bispyranone scaffold [bispyran-(2 and 4)-ones] have been elaborated in a one-step coupling reaction of 4-hydroxycoumarin or triacetic acid lactone with chromone-3-carboxylic acid or formyl-functionalized precursors (ω-formyl-2’-hydroxyacetophenones and chromone-3-carbaldehydes). Finally, the application of the 1,4-conjugate addition approach is extended to a variety of 4-hydroxypyran-2-ones reacting with α,β-unsaturated ketones, including chalcones, to give the new warfarin-analogues. Also a variety of complex structures have been obtained by hybridizing 4-hydroxycoumarin or triacetic acid lactone units with the newly synthesized poly-substituted- chromones. All the above organic reactions proceeds in mild and environmentally friendly conditions using 4-pyrrolidinopyridine as basic organocatalyst. The structures of the novel polyphenolic hybrids have been characterized by high resolution spectroscopic techniques including extensive 1D, 2D-NMR and single-crystal X-ray diffractometry which largely helped to solve the structural complexity. The fourth chapter briefly introduces the biological screenings performed on the novel synthesized polyphenolic hybrids showing their possible involvement in cancer therapy. Most of the newly obtained molecules have been evaluated for their effect on cytotoxicity and proliferation of leukemic cell lines and their involvement in regulation of NF-κB pro-inflammatory pathway, in which the biscoumarin hybrids exhibited high activities (IC50 = 6-19 μM for NF-κB inhibition after 8 hours of incubation and IC50 = 15-39 μM for cytotoxic effects on cancer cell after 24 hours of incubation). Moderate inhibitions of HDAC and Cdc25 enzymes are noticed for the previously mentioned benzofuran-3-one-hydantoin candidates. Fourteen polysubstituted benzopyran-4-one based polyphenolics were examined for their cancer chemopreventive activity mediated by induction of cytoprotective Nrf2 (nuclear factor E2-related protein 2) signalling and their ability to inhibit proliferation of breast cancer cells. Derivatives of the chromanone class were identified as the most potent inducers of Nrf2 activity. The concentrations required to increase luciferase activity by 10-fold (C10) were 2.8-21.3 μM. All the new cytotoxic and anti-proliferative polyphenolic hybrids did not affect the growth of healthy peripheral blood mononuclear cells (PBMC) (IC50 > 50 μM), indicating their selectivity for cancer cells, which make some of them interesting lead structure for further analyses. Antioxidant activity evaluations using DPPH free radical scavenging and ferric ion reducing FRAP tests have been carried out on some underlined polyphenolic hybrid structures.
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Shikanga, EA, S. Combrinck, and T. Regnier. "South African Lippia herbal infusions: Total phenolic content, antioxidant and antibacterial activities." Elsevier, 2010. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1001254.

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Abstract Lippia javanica and Lippia scaberrima are used as herbal remedies and are commercially traded as health teas in southern Africa under the brands “Mosukujane” and “Musukudu”, respectively. This study evaluates the relationship between the presence of phenolic compounds and the antioxidant activities of infusions prepared from four Lippia species (L. javanica, L. scaberrima, L. rehmannii and L. wilmsii) indigenous to South Africa. The antioxidant activities of the infusions, determined by the 2,2-diphenylpycrylhydrazyl (DPPH) method, were also compared to those of popular black, green and herbal tea brands. Of the four indigenous species, infusions of L. javanica and L. wilmsii exhibited the highest antioxidant activities (EC50: 358 and 525 μg/ml, respectively) and contained the most phenolic compounds (14.8 and 14.5 mg/ml of dry weight gallic acid equivalent, respectively). Antibacterial activities of methanolic extracts of the four Lippia species were determined against four human pathogens (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Pseudomonas aeruginosa). The extract of L. javanica was the most active against all the pathogens tested. Those Lippia species (L. javanica and L. wilmsii) previously reported to produce higher levels of the pharmacologically active phenylethanoid glycosides verbascoside and isoverbascoside, portrayed stronger antioxidant and antibacterial activities. This study gives credence to the use of infusions of these Lippia species for their general health benefits.
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Alansari, Wafa S. "Antioxidant and angiotensin converting enzyme inhibitory activities from bovine serum albumin." Thesis, University of Surrey, 2016. http://epubs.surrey.ac.uk/810091/.

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Bioactive peptides represent an important source of health promoting food. Therefore, the objective of this study was to identify the in vitro antioxidant and ACE inhibitory peptides derived from bovine serum albumin (BSA) and to characterise them after further purification. To achieve this objective, BSA was hydrolyzed with pepsin enzyme, fractionated by ultrafiltration using a 10 kDa molecular weight cut off membrane, and purified by gel filtration chromatography prior to characterisation. The total antioxidant activity was evaluated in a linoleic acid model system using the ferric thiocyanate (FTC) and thiobarbituric acid reactive species (TBARS) methods. The results indicated that gel filtration fraction number 18 exhibited the highest FTC antioxidant activity (65.4 %) compared to the (< 10 kDa) ultrafiltration fraction (44.8 %) and BSA hydrolysate (34.9 %) using a concentration of 1mg peptide/ml. However, the peptide activities were lower than those of 0.01 % butylated hydroxyanisole (69.9 %) and 0.01 % trolox (78.5 %) (P ≤ 0.05). Likewise, TBARS inhibition values were 42.8, 54.8, 76.7 and 84.4 % for BSA hydrolysate, < 10 kDa, BHA and trolox, respectively. The antioxidant activity of the (Mw < 10 kDa) peptide was demonstrated by strong free radical scavenging using the 1, 1-diphenyl-2-picrylhydrazyl (DPPH•), hydroxyl (OH•) and superoxide anion (O2-•); ferric (Fe3+) reducing and ferrous (Fe2+) metal ion chelating capacity and reducing power activity. A second gel filtration fraction number 22 exhibited the highest ACE inhibitory activity (79.5%) compared to the (10 kDa) ultrafiltration fraction (44.7%) and BSA hydrolysate (33.2 %) at a concentration of 10 mg/ml, with corresponding low IC50 values of 0.32, 0.56 and 0.75 mg/ml respectively compared to captopril (88.5%, P ≤ 0.05). The peptide (GF 18) at 1 mg/ml had no cytotoxic effect in epithelial caco-2 cells. Moreover, the presence of the peptide showed high cell viability (99.7%) and reduced malondialdehyde formation (27.7 µg/ml) compared with cells treated with 3mM t-BHP alone, which showed low cell viability (54.6%) and high MDA (30.3 µg/ml) (P < 0.01). BSA peptides protected t-BHP treated cells from caspase-dependent apoptosis; inhibited intracellular ROS production and increased glutathione level and SOD activity. Similarly, the GF 22 peptides (1 mg/ml) protected the endothelial EA.hy 926 against 3mM t-BHP damage and showed reduced mROS production by both lucigenin-enhanced chemiluminescence and the DHE fluorescence techniques. Additionally, the peptides reduced nitrite concentration and inhibited the activity of angiotensin converting enzyme in a dose dependent manner. This study reports novel findings showing that BSA peptides have antioxidant and ACE inhibitory activities that could potentially be used as food supplements and pharmaceutical agents.
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Biler, Michal. "Molecular insights in tracking optical properties and antioxidant activities of polyphenols." Thesis, Limoges, 2017. http://www.theses.fr/2017LIMO0001/document.

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Les polyphénols sont abondamment trouvés dans de nombreux fruits, légumes, boissons etc. et ils possèdent de nombreux effets bénéfiques pour la santé. Les méthodes de calcul ont été utilisées dans le cadre de cette thèse pour rationaliser, décrire et prédire les propriétés physiques et chimiques des flavonolignanes et des pyranoanthocyanines pour la compréhension de leurs actions biologiques au niveau moléculaire. Tous les résultats des calculs théoriques ont été discutés par rapport aux données expérimentales. Les propriétés liées à l'activité antioxydante des flavonolignanes ont été étudiées par les méthodes de la théorie de la densité fonctionnelle (DFT). La dépendance au pH des propriétés d'absorption UV/Vis des flavonolignanes et des pyranoanthocyanines ont été évaluée par des méthodes DFT dépendante du temps (TD-), et les interactions non-covalentes ont été étudiées avec les méthodes de DFT incluant la correction de dispersion. Un bref aperçu est également donné sur l'interaction de ces composés avec des biomolécules. Le chapitre 6 présente des résultats non encore publiés de plusieurs systèmes non-covalents pigment: copigment. Cette partie des résultats constitue un bon point de départ pour la recherche du ‘meilleur copigment’
Polyphenols are abundantly found in many fruit, vegetables, beverages, etc. and they possess many potential health benefits. Computational methods were thoroughly used through this thesis to rationalize, describe and predict physical chemical properties of flavonolignans and pyranoanthocyanins. Here, we aim at an understanding of polyphenol biological actions at a molecular level. All outcomes from the theoretical computations were discussed with respect to experimental data. The properties related to antioxidant activity of flavonolignans were investigated by density functional theory (DFT) methods. The pH dependence of ultraviolet/visible (UV/Vis) absorption properties of flavonolignans and pyranoanthocyanins were evaluated by time dependent (TD-) DFT methods, and noncovalent interactions were investigated within dispersion-corrected DFT methods. A short overview is also given on interaction of such compounds with biomolecules. Chapter 6 presents yet not published results of several noncovalent pigment: copigment systems. This part of the results serves as a good starting point to search for ‘the best copigment’
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Amiri, Negar. "Antioxidant and angiotensin converting enzyme inhibitory activities of soya protein extracts." Thesis, University of Surrey, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616923.

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Soy protein isolate was hydrolysed with gastrointestinal enzymes, pepsin and pancreatin. The hydrolysate (SPH) was sequentiaUy fractionated using ultrafiltration (UF), gel filtration (GF) and high performance liquid chromatography (HPLC) and tested at each stage to select the bioactive fractions. All fractions were tested for antioxidant activity by the peroxide value and TBARS methods in a linoleic acid containing system. Compared to the untreated control the GF fraction (GFF36) significantly decreased (p < 0.05) TBARS production to 0.02 /-lg/ml like synthetic BHT. Further purification with HPLC did not improve the antioxidant activity (TBARS 0.13 /-lg/rnl). Investigation of the mechanism of antioxidant activity showed that SPH and the 2 kD fraction scavenged superoxide, hydroxyl radical and DPPH free radicals and chelated iron. SPH showed hydrogen peroxide scavenging activity. The 2, 5 and 10 kD fractions demonstrated copper chelating activity in a copper-pyridine pyrocatechol system. The 2 kD fraction also formed complexes with copper and catalysed ascorbic acid oxidation. Affinity chromatography purified fraction (P4 fraction) from SPH chelated copper. Additionally, 300 /-lg/ml P4 prevented copper dependent LDL oxidation (antioxidant activity 54.57%); however, this was less effective than the GFF 36 fraction which had 56.84 % antioxidant activity at only 10 /-lg/ml. All soya fractions exhibited ACE inhibitory activity, especially the UF and GF fractions containing smaller peptides. However, further purification by HPLC to three fractions (HPF15, 16 and 17) showed less activity than the parent GFF 57 fraction. The ACE inhibitory activity values for the SPH, 10 kD, 5 kD, 2 kD, GFF 57 and HPFs 15, 16 and 17 fractions were 17.70, 29.50, 43.66, 58.87, 84.68, 32.18, 44.07 and 20.86 % respectively. Fractions from soy protein isolate comprising potent peptides and possibly polyphenols demonstrated antioxidant, antihypeliensive and anticancer properties in vitro; these fractions could be developed further as neutraceuticals.
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Books on the topic "Antioxidant activities"

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Cultivars: Chemical Properties, Antioxidant Activities and Health Benefits. Nova Science Pub Inc, 2013.

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Abelson, John N., Helmut Sies, and Melvin I. Simon. Nitric Oxide, Part C: Biological and Antioxidant Activities. Elsevier Science & Technology Books, 1998.

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(Editor), John N. Abelson, Melvin I. Simon (Editor), and Helmut Sies (Editor), eds. Methods in Enzymology, Volume 301: Nitric Oxide, Part C: Biological and Antioxidant Activities (Methods in Enzymology). Academic Press, 1998.

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Sellam, K. Chemical Composition, Antioxidant and Antimicrobial Activities of Essential Oil of Warionia saharae from Oases of Morocco. INTECH Open Access Publisher, 2012.

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Ohta, Hitomi. Effects of NK-4, a Cyanine Dye with Antioxidant Activities: Attenuation of Neuronal Deficits in Animal Models of Oxidative Stress-Mediated Brain Ischemia and Neurodegenerative Diseases. INTECH Open Access Publisher, 2012.

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Book chapters on the topic "Antioxidant activities"

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Sun, Ting, and Joseph R. Powers. "Antioxidants and Antioxidant Activities of Vegetables." In Antioxidant Measurement and Applications, 160–83. Washington, DC: American Chemical Society, 2007. http://dx.doi.org/10.1021/bk-2007-0956.ch012.

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Nabi, Shabnum. "Deregulation of Antioxidant Activities." In Toxic Effects of Mercury, 121–27. New Delhi: Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1922-4_16.

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Arunachalam, Karuppusamy, and Sreeja Puthanpura Sasidharan. "Experiments of Antioxidant Activities." In Springer Protocols Handbooks, 143–55. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1233-0_15.

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Mohan, S. Chandra, and Anand Thirupathi. "Antioxidant and Antibacterial Activities of Polysaccharides." In Polysaccharides of Microbial Origin, 553–78. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-42215-8_32.

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Mohan, S. Chandra, and Anand Thirupathi. "Antioxidant and Antibacterial Activities of Polysaccharides." In Polysaccharides of Microbial Origin, 1–27. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-35734-4_32-1.

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Lucas, Mariana, Marisa Freitas, Félix Carvalho, Eduarda Fernandes, and Daniela Ribeiro. "Antioxidant and Pro-oxidant Activities of Carotenoids." In Plant Antioxidants and Health, 1–27. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45299-5_4-1.

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Lucas, Mariana, Marisa Freitas, Félix Carvalho, Eduarda Fernandes, and Daniela Ribeiro. "Antioxidant and Pro-oxidant Activities of Carotenoids." In Plant Antioxidants and Health, 123–48. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-78160-6_4.

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Jhoo, Jin-Woo. "Antioxidant and Anti-Cancer Activities of Green and Black Tea Polyphenols." In Antioxidant Measurement and Applications, 215–25. Washington, DC: American Chemical Society, 2007. http://dx.doi.org/10.1021/bk-2007-0956.ch015.

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Lu, Yanshan, Zhipeng Su, and Yongguang Bi. "Antioxidant Activities of Polysaccharides from Citrus Peel." In Lecture Notes in Electrical Engineering, 1801–7. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-3648-5_233.

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Pathak, Kratika, Sunita Kataria, and Rekha Gadre. "Trending Methods to Enhance Antioxidant Activities in Wheat." In Wheat Production in Changing Environments, 241–60. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6883-7_11.

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Conference papers on the topic "Antioxidant activities"

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Todorović, Jovana D., Aleksandra D. Vesić, Nevena N. Petrović, and Marijana M. Kosanić. "Edible mushrooms as promising antioxidants." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.300t.

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Antioxidant activity of the acetone extracts of the mushrooms Macrolepiota procera and Chlorophyllum rhacodes has been screened in vitro by using different methods (DPPH radical scavenging and reducing power assay), and also it has been determined the total phenolic compounds as total flavonoid content. The research findings indicate that the acetone extract of M. procera demonstrated superior antioxidant activities when compared to C. rhacodes. Similarly, the mushroom M. procera displayed a more pronounced effect on reducing power. In addition, the total content of phenol and flavonoid in extracts were determined as pyrocatechol equivalent, and as rutin equivalent, respectively. A higher content of total phenols and flavonoids was detected in the extract of M. procera. The strong relationships between total phenolic and flavonoid contents and the antioxidative activities of tested extracts imply that these compounds have a significant impact on antioxidant activity. The present study highlights that the tested mushroom species exhibit potent antioxidant properties and can be regarded as valuable sources of natural antioxidants.
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Malhotra, Rohit, Tamil Selvan Chandrasekaran, Keshav Anand, and Louis Cojandaraj. "Phytochemicals and antioxidant activities of Nitophyllum marginale." In 14TH INTERNATIONAL CONFERENCE ON MATERIALS PROCESSING AND CHARACTERIZATION 2023. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0192540.

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Fitriana, Wiwit Denny, Devi Anggraini Putri, and Sri Fatmawati. "Antioxidant and antibacterial activities of rhizomes extracts." In THE FOURTH AL-NOOR INTERNATIONAL CONFERENCE FOR SCIENCE AND TECHNOLOGY (4NICST2022). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0206541.

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Sovrlić, Miroslav, Nedeljko Manojlović, Marijana Kosanić, Aleksandar Kočović, Jovica Tomović, and Perica Vasiljević. "Lichenochemical analysis and in vitro antioxidant activity of extracts and gyrophoric acid from lichen Umbilicaria grisea." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.515s.

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This research investigates the chemical composition, total phenolic and flavonoid content, and antioxidant activity of acetone, methanol, and ethanol extracts of the lichen Umbilicaria grisea, and its major secondary metabolite, gyrophoric acid. The extracts were analyzed using high-performance liquid chromatography (HPLC-UV) and spectrophotometric assays. The results showed significant levels of phenolic compounds and flavonoids, which contribute to the lichen’s antioxidant potential. The antioxidant activity was evaluated using in vitro assays such as DPPH and ABTS radical scavenging activity. The extracts demonstrated potent antioxidant activity, suggesting their potential as natural antioxidants. The identification of bioactive compounds, high phenolic and flavonoid content, and significant antioxidant activity support the potential use of U. grisea as a natural source of therapeutic agents. Further studies are needed to elucidate the underlying mechanisms responsible for these biological activities and evaluate the efficacy and safety of these extracts for potential pharmaceutical applications.
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Gao, Xiaoxv, and Jianguang Chen. "Characterization and antioxidant activities of polysaccharides from Schisandra chinensis." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6029074.

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TUTAR, Prof Dr Ahmet, Prof Dr Ramazan ERENLER, and Raşit Fikret YILMAZ. "Chemical constituents and antioxidant activities of Rhododendron ponticum L." In Annual International Conference on Chemistry, Chemical Engineering and Chemical Process. Global Science & Technology Forum (GSTF), 2015. http://dx.doi.org/10.5176/2301-3761_ccecp15.40.

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Zhu, Linghui, Qing Mo, Jianjun Ma, Jingjing Xu, and Miaoli Fang. "Antioxidant Activities of Polysaccharide Fractions Purified from Corn Bran." In 2017 International Conference on Material Science, Energy and Environmental Engineering (MSEEE 2017). Paris, France: Atlantis Press, 2017. http://dx.doi.org/10.2991/mseee-17.2017.16.

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Fitriana, Adita Silvia, and Sri Royani. "Identifying Antioxidant Activities of Guava Fruit Using DPPH Method." In 1st International Conference on Community Health (ICCH 2019). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.200204.027.

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J. AJEENA, Saba, Zainab A. JABARAH, and Suhayla khalied MOHAMMED. "EVALUATION THE ANTIOXIDANT ACTIVITY OF ALEO VERA LEAVES EXTRACTS." In VII. INTERNATIONAL SCIENTIFIC CONGRESSOF PURE,APPLIEDANDTECHNOLOGICAL SCIENCES. Rimar Academy, 2023. http://dx.doi.org/10.47832/minarcongress7-8.

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Certain chemical compounds, such as biologically active molecules, can be produced and found in high concentrations in plants. Aloe vera plant consists mainly of more than 90% water and many chemical compounds, such as polysaccharides, due to its ability to adapt to desert conditions and environments. More than 200 nutritional substances were found to be exist in aloe vera, including vitamins, enzymes, minerals, polysaccharides, lignin, antioxidants and amino acids. flavonoids and phenols, among the important compounds, play an important and vital role as antioxidants by their function as free radicals’ scavengers. The current research is aiming to investigate the value of total polyphenols , flavonoids and antioxidant activities of magnetized water, non-magnetized water and alcoholic extracts of fresh Aloe Vera leaves .The study showed that the extracts of ethanol and magnetized water are much better than non-magnetized water.
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Đurović, Vesna, Sofija Radenković, Leka Mandić, Mirjana Radovanović, Marijana Pešaković, Ivana Bošković, and Dragutin Đukić. "ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF ZIZYPHUS JUJUBA L. LEAF EXTRACTS." In 2nd International Symposium on Biotechnology. University of Kragujevac, Faculty of Agronomy, 2024. http://dx.doi.org/10.46793/sbt29.53vdj.

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The aim of the present study was to investigate the biological activities of the extracts obtained from leaf of Ziziphus jujuba. To reach this purpose, total phenolic content (TPC), total flavonoid content (TFC), DPPH and ABTS radical scavenging activity, as well as antibacterial activity extracts were evaluated. The content of total phenols in leaf ranged from 22.71 to 28.69 mg GAE/g, the total content of flavonoids ranged from 5.15 mg RE/g to 8.25 mg RE/g depending on the applied extraction method. All extracts showed very high antioxidant activity. The ethanol extracts of Ziziphus jujuba leaf were screened for antibacterial activities against Salmonella typhimurium, Salmonella enteritidis, Listeria ivanovii, Listeria monocytogenes, Staphylococcus aureus and Pseudomonas aerogenes using microdilution method. Furthermore, the highest antibacterial activity was observed against Salmonella typhimurium and Salmonella enteritidis. The present results suggested the promising antioxidant and antibacterial properties of Ziziphus jujuba leaf extracts, which can be used in the fabrication of functional bioactive ingredients for different purposes.
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Reports on the topic "Antioxidant activities"

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Watkins, Chris B., Susan Lurie, Amnon Lers, and Patricia L. Conklin. Involvement of Antioxidant Enzymes and Genes in the Resistance Mechanism to Postharvest Superficial Scald Development. United States Department of Agriculture, December 2004. http://dx.doi.org/10.32747/2004.7586539.bard.

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The objective of this research project was to evaluate the involvement of antioxidant enzymes and genes in the resistance mechanism to postharvest superficial scald development using two primary systems: 1. Resistant and susceptible progenies of an apple cross between a scald resistant crab apple, ‘White Angel’ and a scald susceptible cultivar, ‘Rome Beauty’; 2. Heat-treatment of ‘Granny Smith’, which is known to reduce scald development in this cultivar. In 2002 we asked for, and received (October 14), permission to revise our initial objectives. The US side decided to expand their results to include further work using commercial cultivars. Also, both sides wanted to include an emphasis on the interaction between these antioxidant enzymes and the á-farnesene pathway, with the cooperation of a third party, Dr. Bruce Whitaker, USDA-ARS, Beltsville. Background: Superficial scald is a physiological storage disorder that causes damage to the skin of apple and pear fruit. It is currently controlled by use of an antioxidant, diphenylamine (DPA), applied postharvest by drenching or dips, but concern exists about such chemical usage especially as it also involves application of fungicides. As a result, there has been increased emphasis on understanding of the underlying mechanisms involved in disorder development. Our approach was to focus on the oxidative processes that occur during scald development, and specifically on using the two model systems described above to determine if the levels of specific antioxidants and/or antioxidant enzyme activities correlated with the presence/absence of scald. It was hoped that information about the role of antioxidant-defense mechanisms would lead to identification of candidate genes for future transgenic manipulation. Major conclusions, solutions, achievements: Collectively, our results highlight the complexity of superficial scald developmental processes. Studies involving comparisons of antioxidant enzyme activities in different crab apple selection, commercial cultivars, and in response to postharvest heat and 1-methylcyclopropene (1-MCP) treatments, show no simple direct relationships with antioxidant contents and susceptibility of fruit to scald development. However, a correlative relationship was found between POX activity or isoenzyme number and scald resistance in most of the studies. This relationship, if confirmed, could be exploited in breeding for scald resistance. In addition, our investigations with key genes in the á-farnesenebiosynthetic pathway, together with antioxidant processes, are being followed up by analysis of exposed and shaded sides of fruit of cultivars that show different degrees of scald control by 1-MCP. These data may further reveal productive areas for future research that will lead to long term control of the disorder. However, given the complexity of scald development, the greatest research need is the production of transgenic fruit with down-regulated genes involved in á- farnesene biosynthesis in order to test the currently popular hypothesis for scald development.
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Demirbas, Sefer, and Alpay Balkan. The Effect of H2O2 Pre-treatment on Antioxidant Enzyme Activities of Triticale under Salt Stress. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, August 2020. http://dx.doi.org/10.7546/crabs.2020.08.17.

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Anderson, Sharron, Antony Lloyd, Malcom Baxter, Michael Walls, and Victoria Bailey-Horne. Turmeric survey – Final report. Food Standards Agency, July 2022. http://dx.doi.org/10.46756/sci.fsa.ojv940.

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The consumption of turmeric supplements is increasingly popular and is reported to provide numerous health benefits including antioxidant, analgesic, anti-inflammatory, antiseptic, anticarcinogenic, chemopreventive, chemotherapeutic, antiviral, antibacterial, antifungal and antiplatelet activities [1]. However, in recent months there has been a number of reports of hepatotoxicity linked to the consumption of these supplements. Such reports and scientific publications led to a review of the safety of turmeric and curcumin by the UK Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT). The statement issued by COT in November 2019 concluded “Given past reported contamination issues with turmeric supplements, the Committee concluded that there would be value in commissioning a chemical analysis of turmeric supplements and raw/powdered turmeric available on the UK market”. To address this conclusion the FSA requested Fera to: develop and validate in-house method(s) for measuring curcumin in turmeric containing supplements, ground/powdered turmeric and raw/fresh turmeric develop and validate in-house a method for measuring piperine in turmeric containing supplements purchase turmeric containing supplements (n=15), ground/powdered turmeric (n=10) and raw/fresh turmeric (n=5) from a mixture of local outlets and over the internet analyse all 30 samples for trace elements and curcumin analyse all supplement samples for piperine content.
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