Relevant bibliographies by topics / Antioxidant and DNA damage

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Antioxidant and DNA damage'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Antioxidant and DNA damage"

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DOĞAN, Mustafa. "INVESTIGATION OF DNA DAMAGE AFTER FREEZİNG AND THAWING OF FUNCTIONAL RAINBOW TROUT (Oncorhynchus mykiss) SPERM." International Journal of Agriculture and Environmental Research 10, no. 06 (2024): 902–12. https://doi.org/10.51193/ijaer.2024.10607.

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During thawing and freezing of the sperm cell, the DNA structure may be damaged at different levels due to various internal and external reasons. In this study, DNA damage after freezing and thawing of functional masculinized rainbow trout (Oncorhynchus mykiss) semen was examined. Freezing was carried out using different dilution rates (1/3, 1/6, 1/9) and different doses of 1mM, 2 mM and 4 mM Ascorbic acid (antioxidant). In order to detect these damages that may be seen in the sperm DNA after the thawing process, the Comet assay method was used. The results showed that the group using 1/9 dilu
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Livingston, Justin R., Jacob J. Peterson, Gabriel A. Martinez, et al. "The Antioxidant and DNA Repair Activities of Resveratrol, Piceatannol, and Pterostilbene." Journal of Food Research 4, no. 5 (2015): 9. http://dx.doi.org/10.5539/jfr.v4n5p9.

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<p>Lifestyle diseases represent a large burden on developed societies and account for much morbidity worldwide. Research has shown that eating a diet rich in fruit and vegetables helps to ameliorate and prevent some of these diseases. Antioxidants found in fruits and vegetables may provide a substantial benefit in reducing disease incidence. This study examines the antioxidant properties of resveratrol, piceatannol, and pterostilbene, and the ability of Burkitt’s Lymphoma (Raji) cells to uptake these three antioxidants. It also studies the effect of the antioxidants in protecting against
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Davison, G. W., C. M. Hughes, and R. A. Bell. "Exercise and Mononuclear Cell DNA Damage: The Effects of Antioxidant Supplementation." International Journal of Sport Nutrition and Exercise Metabolism 15, no. 5 (2005): 480–92. http://dx.doi.org/10.1123/ijsnem.15.5.480.

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The purpose of this investigation was to determine the effects of antioxidant supplementation on DNA damage following exercise. Fourteen subjects were randomly assigned to one of two groups and required to ingest either antioxidants (400 mg α-lipoic acid, 200 mg co-enzyme Q10, 12 mg manganese, 600 mg vitamin C, 800 mg N-acetyl cysteine, 400 μg selenium, and 400 IU α-tocopherol per day) or placebos for 7 d. Exercise increased DNA damage, PS, FRAP, and LDH (P < 0.05), but not selectively between groups. LDH and PS concentration decreased 1 h post-exercise (P < 0.05), while LH concentration
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Wong, W. S. Fred, Tze Khee Chan, W. S. Daniel Tan, Hong Yong Peh, and Bevin P. Engelward. "Direct aeroallergen exposure disrupts the oxidant and antioxidant balance in human bronchial epithelial cells." Journal of Immunology 196, no. 1_Supplement (2016): 53.4. http://dx.doi.org/10.4049/jimmunol.196.supp.53.4.

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Abstract Exposure to aeroallergens is a major risk factor for asthma development. Allergen possessing proteolytic activity is capable of disrupting airway epithelium. Increasing evidence pointing to asthma as an epithelial disease, however, the underlying mechanisms that drive asthma are not fully elucidated. Here, we investigated the DNA damage potential of aeroallergens on human bronchial epithelial cells BEAS-2B, and elucidated the damaging mechanisms. We exposed BEAS-2B cells to house dust mite (HDM), and measured DNA damage by CometChip and DNA double strand breaks (DSBs) by γH2AX stainin
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Biswas, Jaydip, Dona Sinha, Sutapa Mukherjee, Soumi Roy, Maqsood Siddiqi, and Madhumita Roy. "Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal." Human & Experimental Toxicology 29, no. 6 (2010): 513–24. http://dx.doi.org/10.1177/0960327109359020.

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Groundwater arsenic contamination has been a health hazard for West Bengal, India. Oxidative stress to DNA is recognized as an underlying mechanism of arsenic carcinogenicity. A phytochemical, curcumin, from turmeric appears to be potent antioxidant and antimutagenic agent. DNA damage prevention with curcumin could be an effective strategy to combat arsenic toxicity. This field trial in Chakdah block of West Bengal evaluated the role of curcumin against the genotoxic effects of arsenic. DNA damage in human lymphocytes was assessed by comet assay and fluorescence-activated DNA unwinding assay.
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Merlin, J. P. Jose, Sabateeshan Mathavarajah, Graham Dellaire, Kieran P. J. Murphy та H. P. Vasantha Rupasinghe. "A Dietary Antioxidant Formulation Ameliorates DNA Damage Caused by γ-Irradiation in Normal Human Bronchial Epithelial Cells In Vitro". Antioxidants 11, № 7 (2022): 1407. http://dx.doi.org/10.3390/antiox11071407.

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Antioxidants can be used as radioprotectants to reduce DNA damage due to exposure to radiation that could result in malignancies, including lung cancer. Mortality rates are consistently higher in lung cancer, which is usually diagnosed at later stages of cancer development and progression. In this preliminary study, we examined the potential of an antioxidant formulation (AOX2) to reduce DNA damage using a cell model of human normal bronchial epithelial cells (BEAS-2B). Cells were exposed to γ-irradiation or smoke-related hydrocarbon 4[(acetoxymethyl)nitrosamino]-1 (3-pyridyl) 1-butanone (NNKO
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Costantini, David, Shelly Masi, Lyna Rachid, Marielle Beltrame, Mélanie Rohmer, and Sabrina Krief. "Mind the food: rapid changes in antioxidant content of diet affect oxidative status of chimpanzees." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 320, no. 5 (2021): R728—R734. http://dx.doi.org/10.1152/ajpregu.00003.2021.

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The link between dietary antioxidants and oxidative status has been studied extensively in humans. Surprisingly, comparative data are not available from closely related species, such as chimpanzees, which evolved in environments characterized by strong fluctuations in the availability and quality of vegetable food sources. We tested the hypothesis that an abrupt decrease in dietary antioxidants would increase oxidative damages in captive chimpanzees ( Pan troglodytes), while a rapid increase in antioxidant intake would decrease oxidative damages accrued while on the low-antioxidant diet. An ab
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Das, Sonali, Raghavendra L. S. Hallur, and Asit Baran Mandal. "Evaluation of Semecarpus kurzii Engler from Bay Islands for oxidative DNA damage protective activity and in vitro antioxidant potential." Biomedicine 43, no. 02 (2023): 595–602. http://dx.doi.org/10.51248/.v43i02.1961.

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Introduction and Aim: Harnessing traditional knowledge of medicinal plants is important for the betterment of mankind. We must safeguard traditional knowledge from misuse by miscreants living in modern societies and knowledge must be available in the public domain for use in drug designing in the healthcare system. Since the beginning of recorded history, Indians have used plants as a source of medicine, and their cultural past is incredibly rich. This study was conducted to evaluate the oxidative stress-induced DNA damage prevention and antioxidant potential of Semecarpus kurzii found in the
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Elahe, Rezayi Poor Mashizei Dr.Mehri Khatami*. "EVALUATION OF ANTIOXIDANT PROPERTIES CHERRY FRUIT EXTRACT ON PREVENTION THE FAILURE OF DNA." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2051–56. https://doi.org/10.5281/zenodo.834970.

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Free radicals preface can result in many diseases such as atherosclerosis, heart diseases, geriatrics and cancer. These diseases are resulting from irregular production of ROS and unstable mechanism of antioxidant protection system.in order to reduction of harmful effects of ROS, natural antioxidants of plants and synthesis antioxidant can be used. It is shown that phenyl compounds, lipid peroxidations and oxidative damage to DNA in some plants can be prevented through cleaning some ROS such as Hydrogen peroxide and hydrocele radicals. Black Cherry is brimful of these compounds; in addition, r
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Shubham, Kumar1* Dhaval J. Kamothi2 Manju Gari3 Anshuk Sharma4 Meemansha Sharma5 Thakur Uttam Singh6 Dinesh Kumar7. "Effect of oxidative stress on fertility and therapeutic effect of antioxidants." Science World a monthly e magazine 3, no. 2 (2023): 276–80. https://doi.org/10.5281/zenodo.7685603.

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The imbalance between the generation of reactive oxygen species (ROS) and the antioxidant system's beneficial role in neutralizing and removing them causes oxidative stress. An overabundance of ROS generates a pathogenic reaction that damages cells and tissues. Natural antioxidant defense mechanisms exist to reduce the damaging effects of free radicals by neutralizing them and mending damaged cells. Reactive oxygen species (ROS) and antioxidants must coexist in this delicate and challenging equilibrium for healthy cell activity (Pham et al., 2008). ROS are produced as end products when cel
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Dissertations / Theses on the topic "Antioxidant and DNA damage"

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Watters, Joanne Lee Satia Jessie. "Antioxidant nutrients and oxidative DNA damage in healthy African American and White adults." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,1019.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Dec. 18, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Nutrition, School of Public Health." Discipline: Nutrition; Department/School: Public Health.
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Lee-Bellantoni, Margaret S. "Antioxidant defense and redox responses to telomere homolog oligonucleotides in human dermal fibroblasts: a model for investigating redox signaling responses to DNA damage." Thesis, Boston University, 2005. https://hdl.handle.net/2144/37162.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>It has been demonstrated that oligonucleotides homologous to the 3' telomere repeat sequence TTAGGG (T-oligos) stimulate DNA damage responses that are also induced by disruption of the telomere loop structure
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Delinassios, George. "UVA-induced oxidative stress and DNA damage in human skin cells and photoprotection by antioxidant compounds." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/uvainduced-oxidative-stress-and-dna-damage-in-human-skin-cells-and-photoprotection-by-antioxidant-compounds(f9b2b64f-de71-42d4-8787-05c30af81145).html.

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Solar ultraviolet radiation (UVR), especially UVA (320-400nm), is a potent inducer of oxidative DNA damage in human skin cells. Such damage has mutagenic and carcinogenic potential. It is therefore important to understand the mechanisms that control its extent, and develop means of protecting against such damage. The main purpose of this work was to develop reliable quantitative methods to measure UVR-induced oxidative stress, assess its biological consequences and its inhibition, in human skin cells in vitro. Most of this work studied the effects of UVA radiation, as this is the major (&gt;95
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Tang, Hei-man Vincent, and 鄧希文. "Characterization of yeast peroxiredoxin tsa1p in DNA damage response." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085921.

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Tang, Hei-man Vincent. "Characterization of yeast peroxiredoxin tsa1p in DNA damage response." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43085921.

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Dean, Jennifer Dawn. "Flavone the molecular and mechanistic study of how a simple flavonoid protects DNA from oxidative damage /." [Johnson City, Tenn. : East Tennessee State University], 2003. http://etd-submit.etsu.edu/etd/theses/available/etd-1118103-040008/unrestricted/DeanJ111803a.pdf.

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Thesis (M.S.)--East Tennessee State University, 2003.<br>Title from electronic submission form. ETSU ETD database URN: etd-1118103-040008. Includes bibliographical references. Also available via Internet at the UMI web site.
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Abdul, Salam Safnas Farwin. "Biochemistry of Reactive Oxygen Species in Selective Cancer Cell Toxicity and Protection of Normal Cells." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1511880706270521.

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Twigg, Jeremy Philip. "DNA damage in human spermatozoa : free radicals, sperm function and ICSI." Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391610.

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Kaezer, Andrea da Rocha. "Efeito antimutagênico, antigenotóxico, antiobesidade e antioxidante da Ilex paraguariensis (erva-mate)." Universidade do Estado do Rio de Janeiro, 2013. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7016.

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O extrato aquoso de erva-mate, obtido a partir de folhas secas de Ilex paraguariensis, é uma bebida amplamente consumida na América do Sul. Inicialmente, nosso objetivo foi caracterizar os compostos presentes nas amostras de erva-mate disponíveis no mercado brasileiro (CH: chimarrão; T: chá mate torrado; G: chá mate torrado, comercialmente acondicionado em garrafas ou C: em copos; TS: chá mate torrado solúvel A mutagenicidade, citotoxicidade e antimutagenicidade de todas as amostras também foram avaliadas atavés do Teste de Ames na presença e na ausência de ativação metabólica. Em seguida, ana
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England, Timothy George. "Oxidative DNA damage as a marker of cancer risk : effect of dietary antioxidants." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312186.

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Books on the topic "Antioxidant and DNA damage"

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1962-, Evans Mark D., and Cooke Marcus S, eds. Oxidative damage to nucleic acids. Landes Bioscience, 2007.

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Kennedy, Gayle. The effects of dietary antioxidant supplementation on cellular sensitivity to ionising radiation and oxidative DNA damage. The Author], 1997.

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Mosammaparast, Nima, ed. DNA Damage Responses. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2063-2.

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Wolfram, Siede, Kow Yoke Wah, and Doetsch Paul W, eds. DNA damage recognition. Taylor & Francis, 2006.

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Kato, Takamitsu A., ed. DNA Damage Detection. Springer US, 2025. https://doi.org/10.1007/978-1-0716-4574-1.

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Dizdaroglu, Miral, and R. Stephen Lloyd, eds. DNA Damage, DNA Repair and Disease. Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160769.

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Dizdaroglu, Miral, and R. Stephen Lloyd, eds. DNA Damage, DNA Repair and Disease. Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839162541.

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Nickoloff, Jac A., and Merl F. Hoekstra. DNA Damage and Repair. Humana Press, 1998. http://dx.doi.org/10.1385/0896033562.

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Nickoloff, Jac A., and Merl F. Hoekstra. DNA Damage and Repair. Humana Press, 1998. http://dx.doi.org/10.1385/089603500x.

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Nickoloff, Jac A., and Merl F. Hoekstra. DNA Damage and Repair. Humana Press, 2001. http://dx.doi.org/10.1385/1592590950.

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Book chapters on the topic "Antioxidant and DNA damage"

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Majzoub, Ahmad, and Ashok Agarwal. "Antioxidant Therapy." In A Clinician's Guide to Sperm DNA and Chromatin Damage. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71815-6_25.

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Zini, Armand, and Maria San Gabriel. "Antioxidants and Sperm DNA Damage." In Sperm Chromatin for the Clinician. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7843-0_11.

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Zini, Armand, and Maria San Gabriel. "Antioxidants and Sperm DNA Damage." In Sperm Chromatin. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6857-9_30.

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Aruoma, Okezie I., Andrew Jenner, and Barry Halliwell. "Application of Oxidative DNA Damage Measurements to Study Antioxidant Actions of Dietary Components." In Advances in DNA Damage and Repair. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4865-2_2.

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Agarwal, Ashok, and Aspinder Singh. "Sperm DNA Damage and Antioxidant Use: Roles in Male Fertility." In Antioxidants in Male Infertility. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9158-3_10.

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Kiran, Tugba Raika, and Aysun Bay Karabulut. "Free Radicals and Antioxidants in Diabetics." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.5.

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In diabetics, there is an imbalance between free radicals and antioxidants, leading to oxidative stress, a condition characterized by increased production of reactive oxygen species (ROS) and impaired antioxidant defenses. Free radicals, such as superoxide anion (O2•−), hydroxyl radical (•OH), and hydrogen peroxide (H2O2), are generated as by-products of normal cellular metabolism and play a role in cell signaling and immune response. However, excessive ROS production in diabetes, exacerbated by hyperglycemia and insulin resistance, overwhelms antioxidant defenses, which include enzymatic anti
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Dušinská, Mária, and Andrew R. Collins. "DNA Oxidation, Antioxidant Effects, and DNA Repair Measured with the Comet Assay." In Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications. Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9780813814438.ch16.

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Cetik Yildiz, Songul. "Brain and Oxidative Stress." In Brain Biochemistry and Its Disease. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359371.9.

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Brain tissue is more sensitive to oxidative damage due to many different properties than other tissues. So, the need for protection of brain tissue, which is more prone to oxidative damage than other tissues and organs, is greater than other tissues. Oxidative stress is brought on by a disturbance in the balance between antioxidants and free radicals, which have a scavenging effect on them in biological systems. Increased ROS causes cell damage by causing damage to cell membranes, deterioration in the structure and functions of intracellular proteins, and structural damage to DNA. Oxidative st
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Agarwal, Ashok, and Aspinder Singh. "Sperm DNA Damage and Antioxidant Use: Roles in Male Fertility." In Male Infertility. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-3335-4_29.

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Martinez, Marlon P., Ahmad Majzoub, and Ashok Agarwal. "Antioxidants Use and Sperm DNA Damage." In Male Infertility. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-32300-4_47.

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Conference papers on the topic "Antioxidant and DNA damage"

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Aso, T., S. Fukagawa, Y. Hirano, M. Hara, and S. Fujiwara. "Review and Strategy for Implementing Criteria of DNA Damage in an Atomistic Model using Geant4-DNA." In 2024 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD). IEEE, 2024. http://dx.doi.org/10.1109/nss/mic/rtsd57108.2024.10658071.

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Petrović, Sandra, Bojana Laban, Tatjana Momić, and Andreja Leskovac. "EFFECTS OF Phytolacca dioica EXTRACT ON IONIZING RADIATION-INDUCED DAMAGE IN VITRO." In 8th Workshop Food and Drug Safety and Qualit. Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, 2024. http://dx.doi.org/10.46793/8fdsq.pc5sp.

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This pilot study aimed to examine the impact of Phytolacca dioica on ionizing radiation-induced DNA damage and lipid peroxidation using human peripheral blood lymphocytes as a model system. The results showed that P. dioica possesses neither antioxidant nor genoprotective effects in radiolytically damaged tissue. Its potential use as a radiosensitizer should be further examined.
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Antus, Balazs, Csilla Paska, and Imre Barta. "Simultaneous assessment of DNA damage and antioxidant enzyme activity in COPD exacerbations." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa5234.

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Ganapathy, Vengatesh, Jimmy Manyanga, Lacy Brame, et al. "Abstract 3593: Electronic cigarettes induce significant DNA damage and reduce cellular antioxidant levels." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3593.

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Matić, Sanja Lj, Tamara M. Mladenović, Milan P. Mladenović, et al. "Oxidative DNA damage preventive activity of essential oils of three Pinus species: P. mugo, P. sibirica, and P. silvestre." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.321m.

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Pharmacological properties of essential oils of Pinus species are mainly associated with antimicrobial, antioxidant, anticancer, anti-aging, and anti-inflammatory potencies. However, only limited scientific information has been gathered regarding the genotoxic and antigenotoxic activities of Pinus essential oils. Therefore, the aim of the present study was to investigate the in vitro DNA protective activities of three commercial essential oils of Pinus species: P. mugo, P. sibirica, and P. silvestre, against the oxidative damage induced by hydroxyl and peroxyl radicals. The tested essential oi
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Gajski, Goran, Katarina Matkovic, Luka Kazensky, and Marko Gerić. "PESCATARIAN DIET MIGHT BE MORE BENEFICIAL IN TERMS OF MAINTAINING DNA INTEGRITY." In 8th Workshop Food and Drug Safety and Quality. Vinča Institute of Nuclear Sciences - National Institute of the Republic of Serbia, 2024. http://dx.doi.org/10.46793/8fdsq.ilb3gg.

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Certain lifestyle factors such as physical activity and diet can affect a variety of health-related biomarkers and also impact the stability of DNA through the upregulation of the antioxidant defence system and alteration of its repair capacity. Besides, there is growing evidence suggesting that plant-based diets, as well as preferential consumption of fish and seafood, may promote health, longevity, and well-being. Hence, here we aimed to investigate the impact of different dietary preferences on the primary DNA damage in young healthy females residing in Zagreb (Croatia). The participants we
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Matić, Sanja, Pavle Mašković, and Katarina Šipovac. "DNA PROTECTIVE ACTIVITY OF TWO SPECIES OF THE „SCROPHULARIA“ GENUS 2021ICCBIKG (2021)." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.218m.

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Plants from the genus Scrophularia, family Scrophulariaceae have numerous biological activities such as antibacterial, antioxidant, antiprotozoal, antitumor, hepatoprotective, and antidiabetic. However, as far as we know, genotoxic and antigenotoxic effects of these two plant species remain unexplored. The present study aimed to evaluate possible in vivo protective effects of the methanol extracts of two plant species of the Scrophularia genus, Scrophularia canina L. and S. alata Gilib., against carbon tetrachloride (CCl4)-induced DNA damage in albino Wistar rat. A significant increase in tota
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Mahadev Bhat, S., D. Shrestha, N. Massey, L. A. Karriker, A. Kanthasamy, and C. Charavaryamath. "Organic Dust Exposure Induces Mitochondrial Damage and Mitochondrial DNA Release and Organelle Targeted Antioxidant Therapy Appears Protective." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2767.

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Popov, D. Yu, M. S. Kazakov, E. Yu Shitikova, and A. Y. Vinokurov. "LOCALIZATION OF MITOCHONDRIAL DNA MUTATIONS AFFECTS THE PATTERN OF CHANGES IN THE PRODUCTION AND NEUTRALIZATION OF REACTIVE OXYGEN SPECIES BY MITOCHONDRIA." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-205.

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The mechanism of the effect of mtDNA mutations on changes in redox balance depends on their location in the genome. While damage to the cytochrome b gene causes a decrease in the rate of electron leakage into the mitochondrial matrix and intermembrane space and a commensurate decrease in the content of reduced glutathione, mutations of rRNA and tRNA genes or subunits of complex I lead to an increase in AFC formation and deficiency of the antioxidant system.
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Lakkur, Sindhu, Thomas Ahearn, and Roberd Bostick. "Abstract 1854: Effects of supplemental antioxidant micronutrients on oxidative DNA damage marker in normal colorectal mucosa: A randomized clinical trial." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1854.

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Reports on the topic "Antioxidant and DNA damage"

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Patil, Bhimanagouda S., Ron Porat, G. K. Jayaprakasha, and K. N. C. Murthy. Optimization of Postharvest Storage Conditions to Maintain Fruit Quality and Health Maintaining Properties of Grapefruit. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7613879.bard.

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Antioxidant activity of fruits is gaining wide interest among consumers due to its importance in counteracting oxidative stress, free radicals and preventing DNA damage. Oxygen radical absorbance capacity (ORAC) assay is one of the commonly used assays to measure the antioxidant activity, which is based on hydrogen atom transfer mechanism. Furocoumarins present in grapefruit are reported to have antiproliferative activity, induce GST activity, inhibit biofilm formation and increase bioavailability of drugs. In the present project ORAC values were measured of Star Ruby grapefruit undergone ethy
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Watkins, Chris B., Susan Lurie, Amnon Lers, and Patricia L. Conklin. Involvement of Antioxidant Enzymes and Genes in the Resistance Mechanism to Postharvest Superficial Scald Development. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7586539.bard.

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The objective of this research project was to evaluate the involvement of antioxidant enzymes and genes in the resistance mechanism to postharvest superficial scald development using two primary systems: 1. Resistant and susceptible progenies of an apple cross between a scald resistant crab apple, ‘White Angel’ and a scald susceptible cultivar, ‘Rome Beauty’; 2. Heat-treatment of ‘Granny Smith’, which is known to reduce scald development in this cultivar. In 2002 we asked for, and received (October 14), permission to revise our initial objectives. The US side decided to expand their results to
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Kisby, Glen. DNA Damage Induced Neuronal Death. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada375640.

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Phoebe L. Stewart. Cryo-EM Imaging of DNA-PK DNA Damage Repair Complexes. Office of Scientific and Technical Information (OSTI), 2005. http://dx.doi.org/10.2172/841088.

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Sevilla, M. D. Mechanisms for radiation damage in DNA. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/7176057.

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Sevilla, M. D. Mechanisms for radiation damage in DNA. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/5018151.

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Green, Brian M. DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-Replication. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada436928.

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Green, Brian M., and Joachim J. Li. DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-replication. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada467931.

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Green, Brian. DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-replication. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada482750.

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Scott, Kenneth L., and Sharon E. Plon. Alternative DNA Damage Checkpoint Pathways in Eukaryotes. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada396714.

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