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1

Thiele, Jens J., Frank Dreher, and Lester Packer. "Antioxidant defense systems in skin." Journal of Toxicology: Cutaneous and Ocular Toxicology 21, no. 1-2 (2002): 119–60. http://dx.doi.org/10.1081/cus-120004330.

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2

Meda, Srikala, Sharda Singh, Philip Palade, Sahil Tonk, and Sanjay Awasthi. "Oxidative stress in intensive care unit patients: a review of glutathione linked metabolism and lipid peroxidation." Southwest Respiratory and Critical Care Chronicles 7, no. 27 (2019): 7–35. http://dx.doi.org/10.12746/swrccc.v7i27.511.

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Despite clear evidence of increased oxidative stress in the blood and tissues of critically ill intensive care unit patients, consistent beneficial effects of many different antioxidants have not been observed, and antioxidant therapy has not yet translated into widely accepted clinical practice. The reasons for this are unclear, likely rooted in the complex and context dependent free radical behavior of antioxidants interacting with the process of lipid peroxidation. Control of lipid peroxidation is a crucial requirement for the beneficial effects of antioxidants, but the interactions of biol
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3

Wu, Jing Qin, Thomas R. Kosten, and Xiang Yang Zhang. "Free radicals, antioxidant defense systems, and schizophrenia." Progress in Neuro-Psychopharmacology and Biological Psychiatry 46 (October 2013): 200–206. http://dx.doi.org/10.1016/j.pnpbp.2013.02.015.

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4

Akisü, Mete, Deniz Yilmaz, Sevgi Tüzün, and Nilgün Kültürsay. "Antioxidant defense systems in newborns undergoing phototherapy." Indian Journal of Pediatrics 66, no. 5 (1999): 651–55. http://dx.doi.org/10.1007/bf02726243.

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5

Raza, Muhammad Asim, Malka Samra Malik, Muhammad Azam, and Muhammad Azam. "Impact of Natural Antioxidants on Biological Systems." Lahore Garrison University Journal of Life Sciences 4, no. 02 (2020): 139–62. http://dx.doi.org/10.54692/lgujls.2019.0402105.

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ABSTRACT:Free radicals are the unstable electron-deficient species that reacts with different molecules to gain stability and to eliminate their unpaired condition. Antioxidant molecules neutralizes the free radicals by donating their electrons and inhibits the unwanted oxidative reactions in biological system. The imbalance between antioxidants and free radicals generated oxidative stress which leads to severe impairment of the biological systems. The purpose of the present review is to highlight the beneficial role of naturally occurring antioxidant systems in minimizing the damage and maint
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6

Gao, Yan, Xuan Dong, Rongjin Wang, et al. "Exogenous Calcium Alleviates Oxidative Stress Caused by Salt Stress in Peanut Seedling Roots by Regulating the Antioxidant Enzyme System and Flavonoid Biosynthesis." Antioxidants 13, no. 2 (2024): 233. http://dx.doi.org/10.3390/antiox13020233.

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Soil salinity is one of the adversity stresses plants face, and antioxidant defense mechanisms play an essential role in plant resistance. We investigated the effects of exogenous calcium on the antioxidant defense system in peanut seedling roots that are under salt stress by using indices including the transcriptome and absolute quantitative metabolome of flavonoids. Under salt stress conditions, the antioxidant defense capacity of enzymatic systems was weakened and the antioxidant capacity of the linked AsA-GSH cycle was effectively inhibited. In contrast, the ascorbate biosynthesis pathway
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7

Badwan, Sami, Elizabeth Bailey, and James M. Harper. "Do Antioxidants Extend Longevity in Invertebrate and Vertebrate Animals?" OBM Geriatrics 07, no. 01 (2023): 1–17. http://dx.doi.org/10.21926/obm.geriatr.2301226.

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In the 1950’s Denham Harman proposed the Free Radical Theory of Aging whereby species lifespan and individual longevities are the consequence of free radical driven damage to biomolecules. This led to decades of research to ascertain the effect of altered antioxidant defense systems on aging and mortality in an array of species using reverse genetics and dietary manipulation. Within invertebrates, the data generally support the Free Radical Theory in that overexpression of antioxidant enzymes or dietary supplementation with antioxidant compounds increases longevity and resistance to oxidative
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8

Hollander, J., M. Gore, R. Fiebig, et al. "Spaceflight Downregulates Antioxidant Defense Systems in Rat Liver." Free Radical Biology and Medicine 24, no. 2 (1998): 385–90. http://dx.doi.org/10.1016/s0891-5849(97)00278-5.

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9

Missirlis, Fanis, John P. Phillips, and Herbert Jäckle. "Cooperative action of antioxidant defense systems in Drosophila." Current Biology 11, no. 16 (2001): 1272–77. http://dx.doi.org/10.1016/s0960-9822(01)00393-1.

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10

Vo, T. K. O., C. Druez, N. Delzenne, H. S. Taper, and M. Roberfroid. "Analysis of antioxidant defense systems during rat heptacarcinogenesis." Carcinogenesis 9, no. 11 (1988): 2009–13. http://dx.doi.org/10.1093/carcin/9.11.2009.

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11

Vliet, Albert Van Der, and Carroll E. Cross. "Innate antioxidant defense systems in the respiratory tract." BioFactors 15, no. 2-4 (2001): 83–86. http://dx.doi.org/10.1002/biof.5520150206.

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12

Sezgin Muslu, Asiye, and Asim Kadioglu. "The antioxidant defense and glyoxalase systems contribute to the thermotolerance of Heliotropium thermophilum." Functional Plant Biology 48, no. 12 (2021): 1241. http://dx.doi.org/10.1071/fp21113.

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This study focused on the impact of the antioxidant defence and glyoxalase systems on extreme heat tolerance of the thermophilic plant Heliotropium thermophilum L. For this purpose, plants were exposed to 20, 40, 60 and 80±5°C soil temperature gradually for 15days under laboratory conditions. Our results showed that the hydrogen peroxide and superoxide levels of H. thermophilum were lower at 40±5°C and higher at 80±5°C compared with plants grown at 20±5°C. Some antioxidant enzyme activities tended to increase in plants at 40, 60 and 80±5°C compared with those at 20±5°C and the protein contents
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13

Kachungwa Lugata, James, Arth David Sol Valmoria Ortega, and Csaba Szabó. "The Role of Methionine Supplementation on Oxidative Stress and Antioxidant Status of Poultry-A Review." Agriculture 12, no. 10 (2022): 1701. http://dx.doi.org/10.3390/agriculture12101701.

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The physiological status of poultry can be disturbed by different stressors that may lead to oxidative stress conditions. Oxidative stress activates defense systems, which mitigates the adverse effects. Several lines of the poultry defense system exist, including enzyme systems such as catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), and non-enzymatic antioxidants such as Glutathione (GSH). Methionine—a vital amino acid in poultry nutrition—plays a significant role in protein synthesis, transsulfuration, and transmethylation and is also involved in several biochemical
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14

Wu, Q. S., Y. N. Zou, W. Liu, X. F. Ye, H. F. Zai, and L. J. Zhao. "Alleviation of salt stress in citrus seedlings inoculated with mycorrhiza: changes in leaf antioxidant defense systems." Plant, Soil and Environment 56, No. 10 (2010): 470–75. http://dx.doi.org/10.17221/54/2010-pse.

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Citrus is a salt-sensitive plant. In the present study, the salt stress ameliorating the effect of arbuscular mycorrhizal fungi through antioxidant defense systems was reported. Three-month-old trifoliate orange (Poncirus trifoliata) seedlings colonized by Glomus mosseae or G. versiforme were irrigated with 0 and 100 mmol NaCl solutions. After 49 days of salinity, mycorrhizal structures were obviously restrained by salt stress. Mycorrhizal inoculation especially G. mosseae significantly alleviated the growth reduction of salinity. There were notably lower malondialdehyde and hydrogen peroxide
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15

Wang, Hao, Liyan Liang, Baoxing Liu, et al. "Arbuscular Mycorrhizas Regulate Photosynthetic Capacity and Antioxidant Defense Systems to Mediate Salt Tolerance in Maize." Plants 9, no. 11 (2020): 1430. http://dx.doi.org/10.3390/plants9111430.

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Salt stress inhibits photosynthetic process and triggers excessive formation of reactive oxygen species (ROS). This study examined the role of arbuscular mycorrhizal (AM) association in regulating photosynthetic capacity and antioxidant activity in leaves of two maize genotypes (salt-tolerant JD52 and salt-sensitive FSY1) exposed to salt stress (100 mM NaCl) in soils for 21 days. The leaf water content, chlorophyll content, and photosynthetic capacity in non-mycorrhizal (NM) plants were decreased by salt stress, especially in FSY1, with less reduction in AM plants than NM plants. Salinity incr
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16

Rao, Muhammad Junaid, Mingzheng Duan, Caixia Zhou, et al. "Antioxidant Defense System in Plants: Reactive Oxygen Species Production, Signaling, and Scavenging During Abiotic Stress-Induced Oxidative Damage." Horticulturae 11, no. 5 (2025): 477. https://doi.org/10.3390/horticulturae11050477.

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Plants face various abiotic stresses in their natural environments that trigger the production of reactive oxygen species (ROS), leading to oxidative stress and potential cellular damage. This comprehensive review examines the interplay between plant antioxidant defense systems and ROS under abiotic stress conditions. We discuss the major enzymatic antioxidants, including superoxide dismutase, catalase, reductases, and peroxidases, as well as non-enzymatic antioxidants, such as ascorbic acid, glutathione, polyphenols, and flavonoids, which play crucial roles in ROS detoxification. This review
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17

Virk, Tuba Latif, Qi Liu, Yuguo Yuan, Xianyu Xu, and Fenglei Chen. "Curcumin as Therapeutic Modulator of Impaired Antioxidant Defense System: Implications for Oxidative Stress-Associated Reproductive Dysfunction." Biology 14, no. 7 (2025): 750. https://doi.org/10.3390/biology14070750.

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One of the critical challenges in assisted reproductive technology (ART) is the inadequacy of effective regulation of reactive oxygen species. Simultaneously, the endogenous antioxidant defense system plays a significant role in combating oxidative stress across various physiological stages of embryonic development. However, these intrinsic defense systems alone are insufficient as they rely on exogenous antioxidants that interact synergistically to enhance and sustain antioxidant capacity. Considering the principal role of antioxidants in mitigating oxidative stress in oocyte growth, identify
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18

Rai, Ruchi, Shilpi Singh, Krishna Kumar Rai, Alka Raj, Sonam Sriwastaw, and L. C. Rai. "Regulation of antioxidant defense and glyoxalase systems in cyanobacteria." Plant Physiology and Biochemistry 168 (November 2021): 353–72. http://dx.doi.org/10.1016/j.plaphy.2021.09.037.

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19

Genc, G. E., Z. Ozturk, and S. Gumuslu. "Selenoproteins are involved in antioxidant defense systems in thalassemia." Metallomics 9, no. 9 (2017): 1241–50. http://dx.doi.org/10.1039/c7mt00158d.

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20

Sanz, Nuria, Carmen Díez-Fernández, Alberto Alvarez, and María Cascales. "Age-dependent modifications in rat hepatocyte antioxidant defense systems." Journal of Hepatology 27, no. 3 (1997): 525–34. http://dx.doi.org/10.1016/s0168-8278(97)80358-3.

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21

Wang, Ying, Larry W. Oberley, and David W. Murhammer. "Antioxidant defense systems of two lipidopteran insect cell lines." Free Radical Biology and Medicine 30, no. 11 (2001): 1254–62. http://dx.doi.org/10.1016/s0891-5849(01)00520-2.

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22

Mastronicola⁎, D., F. Testa, E. Forte, M. Falabella, P. Sarti, and A. Giuffrè. "Antioxidant defense systems in the human parasite giardia intestinalis." Free Radical Biology and Medicine 53 (September 2012): S59. http://dx.doi.org/10.1016/j.freeradbiomed.2012.08.544.

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23

Jovanovic, Zorica. "Antioxidative defense mechanisms in the aging brain." Archives of Biological Sciences 66, no. 1 (2014): 245–52. http://dx.doi.org/10.2298/abs1401245j.

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Aging is an extremely complex, multifactorial process that is characterized by a gradual and continuous loss of physiological functions and responses, particularly marked in the brain. A common hallmark in aging and age-related diseases is an increase in oxidative stress and the failure of antioxidant defense systems. Current knowledge indicates that the level of glutathione progressively declines during aging. Because nerve cells are the longest-living cells that exhibit a high consumption rate of oxygen throughout an individual?s lifetime, the brain may be especially vulnerable to oxidative
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24

Wurlitzer, Wesley Borges, Mateusz Labudda, Joaquim Albenisio G. Silveira, Ronice Drebel Matthes, Julia Renata Schneider, and Noeli Juarez Ferla. "From Signaling to Stress: How Does Plant Redox Homeostasis Behave under Phytophagous Mite Infestation?" International Journal of Plant Biology 15, no. 3 (2024): 561–85. http://dx.doi.org/10.3390/ijpb15030043.

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Plants are directly exposed to several biotic factors. Among these, mite species belonging to the superfamilies Eriophyoidea and Tetranychoidea stand out due to their ability to injure or even transmit viruses to their host plants. In response to infestations by these organisms, reactive oxygen species (ROS), regulated by enzymatic and non-enzymatic antioxidants (homeostasis), can act as signaling molecules to induce defenses or even acclimatization in attacked plants. However, depending on the severity of the stress, there can be an imbalance between ROS and antioxidants that can result in ox
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25

Khan, Adil, Muhammad Numan, Abdul Latif Khan, et al. "Melatonin: Awakening the Defense Mechanisms during Plant Oxidative Stress." Plants 9, no. 4 (2020): 407. http://dx.doi.org/10.3390/plants9040407.

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Melatonin is a multifunctional signaling molecule that is ubiquitously distributed in different parts of a plant and responsible for stimulating several physio-chemical responses to adverse environmental conditions. In this review, we show that, although plants are able to biosynthesize melatonin, the exogenous application of melatonin to various crops can improve plant growth and development in response to various abiotic and biotic stresses (e.g., drought, unfavorable temperatures, high salinity, heavy metal contamination, acid rain, and combined stresses) by regulating antioxidant machinery
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26

D’Oria, Rossella, Rossella Schipani, Anna Leonardini, et al. "The Role of Oxidative Stress in Cardiac Disease: From Physiological Response to Injury Factor." Oxidative Medicine and Cellular Longevity 2020 (May 14, 2020): 1–29. http://dx.doi.org/10.1155/2020/5732956.

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Reactive oxygen species (ROS) are highly reactive chemical species containing oxygen, controlled by both enzymatic and nonenzymatic antioxidant defense systems. In the heart, ROS play an important role in cell homeostasis, by modulating cell proliferation, differentiation, and excitation-contraction coupling. Oxidative stress occurs when ROS production exceeds the buffering capacity of the antioxidant defense systems, leading to cellular and molecular abnormalities, ultimately resulting in cardiac dysfunction. In this review, we will discuss the physiological sources of ROS in the heart, the m
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27

Monsalves, María T., Gabriela P. Ollivet-Besson, Maximiliano J. Amenabar, and Jenny M. Blamey. "Isolation of a Psychrotolerant and UV-C-Resistant Bacterium from Elephant Island, Antarctica with a Highly Thermoactive and Thermostable Catalase." Microorganisms 8, no. 1 (2020): 95. http://dx.doi.org/10.3390/microorganisms8010095.

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Microorganisms present in Antarctica have to deal not only with cold temperatures but also with other environmental conditions, such as high UV radiation, that trigger the generation of reactive oxygen species. Therefore, Antarctic microorganisms must have an important antioxidant defense system to prevent oxidative damage. One of these defenses are antioxidant enzymes, such as catalase, which is involved in the detoxification of hydrogen peroxide produced under oxidative conditions. Here, we reported the isolation and partial characterization of an Antarctic bacterium belonging to the Serrati
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28

Bharti, Vijay K., and R. S. Srivastava. "Pineal Proteins Upregulate Specific Antioxidant Defense Systems in the Brain." Oxidative Medicine and Cellular Longevity 2, no. 2 (2009): 88–92. http://dx.doi.org/10.4161/oxim.2.2.8361.

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The neuroendocrine functions of the pineal affect a wide variety of glandular and nervous system processes. Beside melatonin (MEL), the pineal gland secretes and expresses certain proteins essential for various physiological functions. It has been suggested that the pineal gland may also have an antioxidant role due to secretory product other than MEL. Therefore, the present study was designed to study the effect of buffalo (Bubalus bubalis) pineal proteins (PP) on the antioxidant defense system in the brain of female rats. The twenty-four rats were taken in present study and were divided into
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Vong, Binh, Thuy Trinh, and Nghiep Ngo. "Roles of Reactive Oxygen Species in Diseases and Development of Novel Antioxidant Therapeutics." MedPharmRes 2, no. 4 (2017): 1–6. http://dx.doi.org/10.32895/ump.mpr.2.4.1/suffix.

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Reactive oxygen species (ROS) or oxidative stress has been reported with strongly involving to pathogenesis of many diseases in human. On the other hand, ROS play a critical regulation as secondary signal to maintain intracellular redox equilibrium. Basically, the antioxidant defense systems in the body counteract with overproduced ROS. However, when the redox balance is broken under severe oxidative stress conditions, it leads to tissue injuries and numerous disorders. In this review, we briefly introduce the systems of ROS and antioxidants systems in the body and discuss the opposite roles o
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30

Antinozzi, Cristina, Luigi Di Luigi, Laura Sireno, Daniela Caporossi, Ivan Dimauro, and Paolo Sgrò. "Protective Role of Physical Activity and Antioxidant Systems During Spermatogenesis." Biomolecules 15, no. 4 (2025): 478. https://doi.org/10.3390/biom15040478.

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Oxidative stress is a significant factor that contributes to male infertility and sperm dysfunction. In this condition, an increase in ROS production exceeds the body’s antioxidant defenses, resulting in a decline in spermatozoa quality and fertilizing capacity. Furthermore, excessive ROS production has been linked to the promotion of genomic damage, lipid peroxidation, inflammation, altered enzyme activity, and ultimately, irreversible alterations, cell death, and a decline in seminal parameters associated with male infertility. It is established that physical activity (PA), acting on inflamm
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31

Durak, Ilker. "EFFECTS OF SMOKING ON PLASMA AND ERYTHROCYTE ANTIOXIDANT DEFENSE SYSTEMS." Journal of Toxicology and Environmental Health Part A 56, no. 6 (1999): 373–78. http://dx.doi.org/10.1080/009841099157962.

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32

Di Mascio, P., M. E. Murphy, and H. Sies. "Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols." American Journal of Clinical Nutrition 53, no. 1 (1991): 194S—200S. http://dx.doi.org/10.1093/ajcn/53.1.194s.

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33

Raffa, Monia, Sana Barhoumi, Fatma Atig, Chiraz Fendri, Abdelhamid Kerkeni, and Anwar Mechri. "Reduced antioxidant defense systems in schizophrenia and bipolar I disorder." Progress in Neuro-Psychopharmacology and Biological Psychiatry 39, no. 2 (2012): 371–75. http://dx.doi.org/10.1016/j.pnpbp.2012.07.013.

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34

Qader, Mallique, Jian Xu, Yuejun Yang, Yuancai Liu, and Shugeng Cao. "Natural Nrf2 Activators from Juices, Wines, Coffee, and Cocoa." Beverages 6, no. 4 (2020): 68. http://dx.doi.org/10.3390/beverages6040068.

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Juices, wine, coffee, and cocoa are rich sources of natural polyphenolic compounds that have potent antioxidant activities proven by in vitro and in vivo studies. These polyphenolic compounds quench reactive oxygen and nitrogen species (RONS) or reactive free radicals and act as natural antioxidants which are also able to protect against reactive oxygen species (ROS)-mediated oxidative damage, which elevates cellular antioxidant capacity to induce antioxidant defense mechanisms by modulating transcription factors. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a transcription factor enc
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35

Lebedeva, Ye A. "Antioxidant systems of blood plasma in the pathogenesis of diabetic microangiopathies." Problems of Endocrinology 42, no. 5 (1996): 10–12. http://dx.doi.org/10.14341/probl12080.

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The parameters of lipid peroxidation and enzymatic and low-molecular antioxidant systems of blood plasma were studied in 114 patients with insulin-dependent diabetes mellitus and 51 donors (control group). The activities of extracellular superoxide dismutase, catalase, concentrations of plasma selenium, the activity of red cell glutathione peroxidase, and the level of uric acid were measured. Oxidant stress was found to involve no changes of the enzymatic component of antiperoxide defense in patients both at the debut of the disease and with diabetic angiopathies. Evidently, the cell protectio
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36

Uzma, Javeria, Sai Krishna Talla, Ebenezer Madam, and Praveen Mamidala. "Assessment of Salinity Tolerance Deploying Antioxidant Defense Systems in Gerbera Jamesonii." Biosciences Biotechnology Research Asia 19, no. 1 (2022): 243–54. http://dx.doi.org/10.13005/bbra/2982.

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Inconsistency in the environment exposes plants to various abiotic stresses. This results in damage of a plant’s cellular components due to excessive accumulation of unstable reactive oxygen. Besides, it also disrupts enzymatic/non-enzymatic detoxification mechanisms in plants making them more sensitive. Salinity is one such abiotic stress which disrupts regular physiological mechanisms in plants. In this study, we examined the effects of salinity using NaCl in four different genotypes of Gerbera jamesonii cv Bolus, an important ornamental plant of family Compositae. We hypothesized that, upon
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37

Tewari, Devesh, Artur Jóźwik, Małgorzata Łysek-Gładysińska, et al. "Fenugreek (Trigonella foenum-graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice." Nutrients 12, no. 9 (2020): 2552. http://dx.doi.org/10.3390/nu12092552.

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Fenugreek seeds are widely used in Asia and other places of the world for their nutritive and medicinal properties. In Asia, fenugreek seeds are also recommended for geriatric populations. Here, we evaluated for the first time the effect of fenugreek seed feed supplementation on the liver antioxidant defense systems in aging mice. The study was conducted on 12-months aged mice which were given fenugreek seed dietary supplement. We evaluated the activities of various antioxidant defense enzymes such as superoxide dismutase (SOD), glutathione reductase (GR), and glutathione peroxidase (GPx), and
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38

Bouayed, Jaouad, and Torsten Bohn. "Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses." Oxidative Medicine and Cellular Longevity 3, no. 4 (2010): 228–37. http://dx.doi.org/10.4161/oxim.3.4.12858.

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The balance between oxidation and antioxidation is believed to be critical in maintaining healthy biological systems. Under physiological conditions, the human antioxidative defense system including e.g., superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH) and others, allows the elimination of excess reactive oxygen species (ROS) including, among others superoxide anions (O2.-), hydroxyl radicals (OH.), alkoxyl radicals (RO.) and peroxyradicals (ROO.). However, our endogenous antioxidant defense systems are incomplete without exogenous originating reduci
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Hernández-Carranza, Paola, Raúl Avila-Sosa, Obdulia Vera-López, et al. "Uncovering the Role of Hormones in Enhancing Antioxidant Defense Systems in Stressed Tomato (Solanum lycopersicum) Plants." Plants 12, no. 20 (2023): 3648. http://dx.doi.org/10.3390/plants12203648.

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Tomato is one of the most important fruits worldwide. It is widely consumed due to its sensory and nutritional attributes. However, like many other industrial crops, it is affected by biotic and abiotic stress factors, reducing its metabolic and physiological processes. Tomato plants possess different mechanisms of stress responses in which hormones have a pivotal role. They are responsible for a complex signaling network, where the antioxidant system (enzymatic and non-enzymatic antioxidants) is crucial for avoiding the excessive damage caused by stress factors. In this sense, it seems that h
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40

Vichnevetskaia, Klara D., and D. N. Roy. "Oxidative stress and antioxidative defense with an emphasis on plants antioxidants." Environmental Reviews 7, no. 1 (1999): 31–51. http://dx.doi.org/10.1139/a99-004.

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Increased levels of active oxygen species or free radicals can create an oxidative stress. Concentration of free radicals in living cells increases as a result of exposure to environmental stresses that lead to aging, carcinogenesis, and immunodeficiencies in animals, and membrane leakage, senescence, chlorophyll destruction, and decreased photosynthesis in plants. The antioxidative system of higher plants consists of enzymes, low molecular weight compounds (among them peptides, vitamins, flavonoids, phenolic acids, alkaloids, etc.), and integrated detoxification chains. Enzymatic defense in p
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41

Fan, Silin, Tiantian Xiong, Qiumei Lei, et al. "Melatonin Treatment Improves Postharvest Preservation and Resistance of Guava Fruit (Psidium guajava L.)." Foods 11, no. 3 (2022): 262. http://dx.doi.org/10.3390/foods11030262.

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Guava fruit has a short postharvest shelf life at room temperature. Melatonin is widely used for preservation of various postharvest fruit and vegetables. In this study, an optimal melatonin treatment (600 μmol·L−1, 2 h) was identified, which effectively delayed fruit softening and reduced the incidence of anthracnose on guava fruit. Melatonin effectively enhanced the antioxidant capacity and reduced the oxidative damage to the fruit by reducing the contents of superoxide anions, hydrogen peroxide and malondialdehyde; improving the overall antioxidant capacity and enhancing the enzymatic antio
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42

Parvin, Hasanuzzaman, Bhuyan, Nahar, Mohsin, and Fujita. "Comparative Physiological and Biochemical Changes in Tomato (Solanum lycopersicum L.) Under Salt Stress and Recovery: Role of Antioxidant Defense and Glyoxalase Systems." Antioxidants 8, no. 9 (2019): 350. http://dx.doi.org/10.3390/antiox8090350.

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Salinity toxicity and the post-stress restorative process were examined to identify the salt tolerance mechanism in tomato, with a focus on the antioxidant defense and glyoxalase systems. Hydroponically grown 15 day-old tomato plants (Solanum lycopersicum L. cv. Pusa Ruby) were treated with 150 and 250 mM NaCl for 4 days and subsequently grown in nutrient solution for a further 2 days to observe the post-stress responses. Under saline conditions, plants showed osmotic stress responses that included low leaf relative water content and high proline content. Salinity induced oxidative stress by t
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43

Okassova, Assem K., Valeriy Britko, Didar B. Okassov, et al. "Study of Lipid Peroxidation-antioxidant Defense Systems in Rats under Radiation Exposure." Open Access Macedonian Journal of Medical Sciences 10, A (2022): 236–39. http://dx.doi.org/10.3889/oamjms.2022.8352.

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Abstract
 BACKGROUND: Experimental data on the effect of a high dose of gamma radiation 6 Gy on the activity of antioxidant defense enzymes and lipid peroxidation products (LPO) are presented immunocompetent organs in the body of animals in the experiment. It was found that the effect of ionizing radiation led to an increase in the level of diene conjugates (DC) and malondialdehyde (MDA), inhibition of the activity of catalase (CАT) and glutathione peroxidase (GlP), glutathione reductase (GlR) enzymes in almost all the studied objects, as a result of which the development of oxidative str
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Nam, Yea-eun, Yunsoo Kim, Hye Jin Kim, Minji Jung, and Oran Kwon. "Single and Repeated Supplementation of SOD Differently Improve Antioxidant Capacity Against Exercise Challenges." Current Developments in Nutrition 6, Supplement_1 (2022): 322. http://dx.doi.org/10.1093/cdn/nzac053.063.

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Abstract Objectives Oxidative stress, commonly exposed in our daily life, produces free radicals. Excessively produced free radicals damage body components and eventually promote degenerative diseases. It has been reported that the reinforcement of superoxide dismutase (SOD), the first barrier of the antioxidant system, protects our body from oxidative stress by enhancing the subsequent redox cycle. The use of SOD, an enzymatic antioxidant rather than a simple antioxidant, is still insufficient to evaluate its safety and efficacy. Therefore, the purpose of this study is to evaluate the long-te
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Mahmoud, Aya, Hamada AbdElgawad, Badreldin A. Hamed, Gerrit T. S. Beemster, and Nadia M. El-Shafey. "Differences in Cadmium Accumulation, Detoxification and Antioxidant Defenses between Contrasting Maize Cultivars Implicate a Role of Superoxide Dismutase in Cd Tolerance." Antioxidants 10, no. 11 (2021): 1812. http://dx.doi.org/10.3390/antiox10111812.

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Cadmium (Cd), a readily absorbed and translocated toxic heavy metal, inhibits plant growth, interrupts metabolic homeostasis and induces oxidative damage. Responses towards Cd-stress differ among plant cultivars, and the complex integrated relationships between Cd accumulation, detoxification mechanisms and antioxidant defenses still need to be unraveled. To this end, 12 Egyptian maize cultivars were grown under Cd-stress to test their Cd-stress tolerance. Out of these cultivars, tolerant (TWC360 and TWC321), moderately sensitive (TWC324) and sensitive (SC128) cultivars were selected, and we d
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Song, Changyou, Cunxin Sun, Bo Liu, and Pao Xu. "Oxidative Stress in Aquatic Organisms." Antioxidants 12, no. 6 (2023): 1223. http://dx.doi.org/10.3390/antiox12061223.

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Jordán, María J., Cristina Martínez-Conesa, Sancho Bañón, et al. "The Combined Effect of Mediterranean Shrubland Pasture and the Dietary Administration of Sage By-Products on the Antioxidant Status of Segureña Ewes and Lambs." Antioxidants 9, no. 10 (2020): 938. http://dx.doi.org/10.3390/antiox9100938.

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The objective of this study was to determine if the combined effect of ewe grazing and the incorporation of sage by-products in the lamb feed enhances the Segureña ewe and lamb antioxidant status. For that, the endogenous (related to blood antioxidant enzymes) and exogenous (plasma antioxidant activity) antioxidant systems of ewes and lambs were studied at the physiological stages of lactation, after weaning and at the end of the fattening period. Major results indicated that grazing improved the enzymatic antioxidant defense of ewes during the stressful period of lamb weaning, and also, the a
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Hébert, Claire, and Claude Willemot. "Antioxidant Potential and Strawberry Preservation." HortScience 32, no. 3 (1997): 434C—434. http://dx.doi.org/10.21273/hortsci.32.3.434c.

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Plant antioxidants have gained considerable interest because of their importance for the preservation of produce and also because of their therapeutic properties. There is increasing evidence that these compounds protect plant tissues from stress and that they delay senescence. Seven strawberry cultivars were analyzed to investigate the possible relationship between their antioxidant potential and fruit shelf-life. The antioxidant defense systems studied were free radical scavenging enzymes (SOD, catalase, glutathione reductase, GSH, ascorbate peroxidase, ascorbate free radical reductase), asc
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Ismaeel, Ahmed, Michael Holmes, Evlampia Papoutsi, Lynn Panton, and Panagiotis Koutakis. "Resistance Training, Antioxidant Status, and Antioxidant Supplementation." International Journal of Sport Nutrition and Exercise Metabolism 29, no. 5 (2019): 539–47. http://dx.doi.org/10.1123/ijsnem.2018-0339.

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Resistance training is known to promote the generation of reactive oxygen species. Although this can likely upregulate the natural, endogenous antioxidant defense systems, high amounts of reactive oxygen species can cause skeletal muscle damage, fatigue, and impair recovery. To prevent these, antioxidant supplements are commonly consumed along with exercise. Recently, it has been shown that these reactive oxygen species are important for the cellular adaptation process, acting as redox signaling molecules. However, most of the research regarding antioxidant status and antioxidant supplementati
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Hasanuzzaman, Mirza, M. H. M. Borhannuddin Bhuyan, Faisal Zulfiqar, et al. "Reactive Oxygen Species and Antioxidant Defense in Plants under Abiotic Stress: Revisiting the Crucial Role of a Universal Defense Regulator." Antioxidants 9, no. 8 (2020): 681. http://dx.doi.org/10.3390/antiox9080681.

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Global climate change and associated adverse abiotic stress conditions, such as drought, salinity, heavy metals, waterlogging, extreme temperatures, oxygen deprivation, etc., greatly influence plant growth and development, ultimately affecting crop yield and quality, as well as agricultural sustainability in general. Plant cells produce oxygen radicals and their derivatives, so-called reactive oxygen species (ROS), during various processes associated with abiotic stress. Moreover, the generation of ROS is a fundamental process in higher plants and employs to transmit cellular signaling informa
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