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Journal articles on the topic 'Antioxidant vitamins (A, C, E), free radicals'

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Published: 24 April 2022

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1

Dewi, Ratna Sari, Desy Ayu Irma Permatasari, Tatiana Siska Wardani, and Muladi Putra Mahardika. "Antioxidant Activity Evaluation from Tomatoes’ N-Hexane, Ethyl Asetate, and Water Fraction with DPPH." Journal of Fundamental and Applied Pharmaceutical Science 2, no. 2 (2022): 86–91. http://dx.doi.org/10.18196/jfaps.v2i2.13023.

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Antioxidants are compounds that can stabilize free radicals in the body. Free radicals are highly reactive molecules as they have unpaired electrons to interact with body cell molecules. Tomatoes contain flavonoids, saponins, solanine tannins, folic acid, malic acid, citric acid, protein, fat, vitamins, minerals, and histamine, which can be used as antioxidants. This study aims to evaluate the antioxidant activity of n-hexane, ethyl acetate, water fraction, and ethanol extracts of Tomatoes and to determine the greatest antioxidant activity between n-hexane, ethyl acetate, water and vitamin C.
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Nikolaidis, Michalis G., Chad M. Kerksick, Manfred Lamprecht, and Steven R. McAnulty. "Does Vitamin C and E Supplementation Impair the Favorable Adaptations of Regular Exercise?" Oxidative Medicine and Cellular Longevity 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/707941.

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The detrimental outcomes associated with unregulated and excessive production of free radicals remains a physiological concern that has implications to health, medicine and performance. Available evidence suggests that physiological adaptations to exercise training can enhance the body’s ability to quench free radicals and circumstantial evidence exists to suggest that key vitamins and nutrients may provide additional support to mitigate the untoward effects associated with increased free radical production. However, controversy has risen regarding the potential outcomes associated with vitami
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Buehler, Bruce A. "The Free Radical Theory of Aging and Antioxidant Supplements." Journal of Evidence-Based Complementary & Alternative Medicine 17, no. 3 (2012): 218–20. http://dx.doi.org/10.1177/2156587212441939.

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Free radical excess occurs when cells are exposed to reactive oxygen species greater than the amount that can be neutralized by cellular produced antioxidants such as superoxide dismutase. This is termed oxidative stress, which can be caused by excessive energy intake or external pollutants. Excess free radicals are proposed to increase the rate of cell aging, injury, and mutations leading to a shortened cell life span. Vitamins A, C, and E and flavoproteins are supplements that function as free radical scavengers. Antioxidants are present in natural foods but added amounts beyond the diet may
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4

Richardson, Russell S., Anthony J. Donato, Abhimanyu Uberoi, et al. "Exercise-induced brachial artery vasodilation: role of free radicals." American Journal of Physiology-Heart and Circulatory Physiology 292, no. 3 (2007): H1516—H1522. http://dx.doi.org/10.1152/ajpheart.01045.2006.

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Originally thought of as simply damaging or toxic “accidents” of in vivo chemistry, free radicals are becoming increasingly recognized as redox signaling molecules implicit in cellular homeostasis. Indeed, at the vascular level, it is plausible that oxidative stress plays a regulatory role in normal vascular function. Using electron paramagnetic resonance (EPR) spectroscopy, we sought to document the ability of an oral antioxidant cocktail (vitamins C, E, and α-lipoic acid) to reduce circulating free radicals, and we employed Doppler ultrasound to examine the consequence of an antioxidant-medi
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Kanter, Mitchell M. "Free Radicals, Exercise, and Antioxidant Supplementation." International Journal of Sport Nutrition 4, no. 3 (1994): 205–20. http://dx.doi.org/10.1123/ijsn.4.3.205.

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Free radicals have been implicated in the development of diverse diseases such as cancer, diabetes, and cataracts, and recent epidemic-logical data suggest an inverse relationship between antioxidant intake and cardiovascular disease risk. Data also suggest that antioxidants may delay aging, Research has indicated that free radical production and subsequent lipid peroxidation are normal sequelae to the rise in oxygen consumption with exercise. Consequently, antioxidant supplementation may detoxify the peroxides produced during exercise and diminish muscle damage and soreness. Vitamin E, beta c
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Gautam, Narayan. "Free radicals and vitamin antioxidants in health and lung diseases." Journal of Universal College of Medical Sciences 3, no. 3 (2015): 43–52. http://dx.doi.org/10.3126/jucms.v3i3.24249.

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Several lung diseases have undergone oxidative stress due to free radical insult. Consequently, antioxidant vitamin C and vitamin E play important role in defense against cellular injury by scavenging free radicals. This article reviews the potential mechanism of free radicals generation and vitamin antioxidant defense to link amongst various lung diseases. One of the manifestations of free radical mediated process is lipid peroxidation subsequently producing malondialdehyde (MDA) in these patients. Supplementation of vitamin C and vitamin E as an adjuvant therapy as well as high intake of fre
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Higgins, Madalyn Riley, Azimeh Izadi, and Mojtaba Kaviani. "Antioxidants and Exercise Performance: With a Focus on Vitamin E and C Supplementation." International Journal of Environmental Research and Public Health 17, no. 22 (2020): 8452. http://dx.doi.org/10.3390/ijerph17228452.

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Antioxidant supplementation, including vitamin E and C supplementation, has recently received recognition among athletes as a possible method for enhancing athletic performance. Increased oxidative stress during exercise results in the production of free radicals, which leads to muscle damage, fatigue, and impaired performance. Despite their negative effects on performance, free radicals may act as signaling molecules enhancing protection against greater physical stress. Current evidence suggests that antioxidant supplementation may impair these adaptations. Apart from athletes training at alt
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Tabet, Naji, David Mantle, Zuzana Walker, and Martin Orrell. "Endogenous Antioxidant Activities in Relation to Concurrent Vitamins A, C, and E Intake in Dementia." International Psychogeriatrics 14, no. 1 (2002): 7–15. http://dx.doi.org/10.1017/s1041610202008232.

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Previous reports on the activities of essential endogenous antioxidants such as superoxide dismutase, catalase, and glutathione in dementia patients have not included a simultaneous quantitative assessment of dietary antioxidant intake. This is important because the reported differences in endogenous antioxidant levels among dementia patients may have reflected variations in the total antioxidants' intake. In this study we measured the levels of antioxidant vitamins A, C, and E in the diet of 81 dementia patients and controls at the same time as assessing blood levels of three endogenous antio
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Goldfarb, Allan H. "Nutritional Antioxidants as Therapeutic and Preventive Modalities in Exercise-Induced Muscle Damage." Canadian Journal of Applied Physiology 24, no. 3 (1999): 249–66. http://dx.doi.org/10.1139/h99-021.

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Several mechanisms have been forwarded to explain the etiology of exercise-induced muscle damage. Free-radical mediated processes appear to be an important component of the inflammatory mediated response. Free radicals have also been demonstrated to be a contributing factor in the loss of calcium homeostasis within the cell. Therefore, one of the proposed treatments for preventing or reducing the extent of this damage is the intervention of free-radical mediated processes. Antioxidants are agents that typically work to prevent free-radical mediated alterations within cells by quenching free ra
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Rizkayanti, Rizkayanti, Anang Wahid M. Diah, and Minarni Rama Jura. "Uji Aktivitas Antioksidan Ekstrak Air dan Ekstrak Etanol Daun Kelor (Moringa Oleifera LAM)." Jurnal Akademika Kimia 6, no. 2 (2017): 125. http://dx.doi.org/10.22487/j24775185.2017.v6.i2.9244.

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Moringa (moringa oleifera Lam) leaves contains many molecules as inhibitors for free radicals such as phenolic compounds (phenolic acids, flavonoids, quinones, coumarins, lignans, stilbenes, tannins), nitrogen compounds (alkaloids, amines, betalain), vitamins, terpenoids (including carotenoids), and several other endogenous metabolites as antioxidants. This study aimed to determine the antioxidant potency of water and ethanol extracts of moringa (moringa oleifera Lam) leave obtained by maceration and dekok. The concentration of free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) was analyzed usi
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Chiuman, Linda, and Nelvi Sutanto. "A Healthier Antioxidants-Rich Food with Vitamin C and E." Indonesian Journal of Global Health Research 2, no. 2 (2020): 111–16. http://dx.doi.org/10.37287/ijghr.v2i2.96.

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There is no doubt that the incredible advances in medicine will be perceived as one of the spectacular achievements of the twentieth century right along with some other innovations. Hazards such as radiation, pollution, smoke, nutrient poor diet handle many common diseases. This article demonstrates knowledge of the antioxidant to practice real preventive medicine by understanding the role that free radicals play in the onset and progression of known disease and how antioxidants can control them.
 Keywords: antioxidant; antioxidant activity; free radicals, vitamin C, vitamin E
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Wattamwar, P. B., AMAR UMAKANT UPASE, S. B. Gholve, S. G. Zingade, and O. G. Bhusnure. "Formulation and Evaluation of Traditional Antioxidant Grape Seeds Extract in the Form of Tablets." Journal of Drug Delivery and Therapeutics 9, no. 5 (2019): 110–13. http://dx.doi.org/10.22270/jddt.v9i5.3228.

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Oxygen uptake while breathing cause’s free radical production and in addition to that environmental factors such as pollutants, smoke and certain chemicals also contribute to their formation. Reactive oxygen species is a collective term that includes all reactive forms of oxygen, including both oxygen radicals and several non-radical oxidizing agents that participate in the initiation and/or propagation of chain reaction. Free radicals are atoms, molecules or ions with unpaired electrons that are highly unstable and active towards chemical reactions with other molecules. Antioxidant is any sub
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13

Powers, Scott K., and Shannon L. Lennon. "Analysis of cellular responses to free radicals: focus on exercise and skeletal muscle." Proceedings of the Nutrition Society 58, no. 4 (1999): 1025–33. http://dx.doi.org/10.1017/s0029665199001342.

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Muscular exercise results in an increased production of radicals and other forms of reactive oxygen species (ROS). Recent evidence suggests that radicals and other ROS are an underlying aetiology in exercise-induced disturbances in muscle redox status. These exercise-induced redox disturbances in skeletal muscle are postulated to contribute to both muscle fatigue and/or exercise-induced muscle injury. To defend against ROS, muscle cells contain complex cellular defence mechanisms to reduce the risk of oxidative injury. Two major classes (enzymic and non-enzymic) of endogenous protective mechan
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14

Chan, Alvin C. "Partners in defense, vitamin E and vitamin C." Canadian Journal of Physiology and Pharmacology 71, no. 9 (1993): 725–31. http://dx.doi.org/10.1139/y93-109.

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In addition to the enzymic mechanism of free-radical removal, essential nutrients that can scavenge free radicals, such as vitamins E and C, constitute a strong line of defense in retarding free radical induced cellular damage. Distinct pathways for the repair of oxidized vitamin E in human cells have been recently identified. Within 0.5 min after the addition of arachidonic acid to a human platelet homogenate, over half of the platelet vitamin E and added arachidonate were metabolized by platelet cyclooxygenase and lipoxygenase pathways. After adding nordihydroguaiaretic acid, a lipoxygenase
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15

Rahmah, Widya, Hasyrul Hamzah, Siti Hajar, Sylvan Septian Ressandy, and Erlisa Maharani Putri. "POTENTIAL OF MATOA FRUIT EXTRACT (POMETIA PINNATA) AS ANTIOXIDANT SOURCE." Jurnal Farmasi Sains dan Praktis 7, no. 1 (2021): 59–66. http://dx.doi.org/10.31603/pharmacy.v7i1.4240.

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Pometia pinnata or commonly known as matoa is a typical plant of Eastern Indonesia or Papua that grows throughout the Papua archipelago. Matoa contains alkaloids, saponins, tannins, flavonoids, phenolic compounds, terpenoids, and vitamins A, C, E which can boost the immune system. The study aims to examine whether the matoa (Pometia pinnata) has acted as a source of antioxidants where one of the functions of the antioxidants themselves is to increase the body's immune system by fighting free radicals. This study uses a narrative review approach, which is a secondary research method that does n
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Mohsina Hyder, Raja D, Visakh Varma, and Ponnusankar S. "Oxidative stress during insulin resistance in prediabetes : a review on role of antioxidants." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 3511–20. http://dx.doi.org/10.26452/ijrps.v11i3.2503.

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Oxidative stress is one of the major causal factors behind insulin resistance during prediabetes. It can impair insulin signalling by triggering stress activated signaling pathways and can also directly oxidize and damage the proteins of these pathways. Although cells have impressive stock of antioxidant enzymes and minor antioxidant moieties, these agents may not be adequate to maintain the redox balance during oxidative stress. The important functional antioxidant vitamins for tissue protection from excess free radicals comprises vitamin C, E and A. Vitamin C can improve insulin resistance b
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Chen, Alex F., Dan-Dan Chen, Andreas Daiber, et al. "Free radical biology of the cardiovascular system." Clinical Science 123, no. 2 (2012): 73–91. http://dx.doi.org/10.1042/cs20110562.

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Most cardiovascular diseases (CVDs), as well as age-related cardiovascular alterations, are accompanied by increases in oxidative stress, usually due to increased generation and/or decreased metabolism of ROS (reactive oxygen species; for example superoxide radicals) and RNS (reactive nitrogen species; for example peroxynitrite). The superoxide anion is generated by several enzymatic reactions, including a variety of NADPH oxidases and uncoupled eNOS (endothelial NO synthase). To relieve the burden caused by this generation of free radicals, which also occurs as part of normal physiological pr
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Afifi, Mohamed, and Ali Alkaladi. "Antioxidant system in Uromastyx philbyi during hibernation and activity periods." Open Life Sciences 9, no. 9 (2014): 864–68. http://dx.doi.org/10.2478/s11535-014-0318-x.

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AbstractHibernation is an extreme physiological state characterized by profound decreases in oxidative metabolism and body temperature during bouts of prolonged torpor, interrupted by brief periods of arousal with sudden increases in oxidative metabolism, with alterations in antioxidant defenses. We monitored the activities of antioxidant enzymes and oxidative stress during hibernation and activity in Uromastyx philbyi. 20 animals were used, 10 of which were collected in the hibernation season (group I) and the other 10 collected during the active period (group II). Blood, liver, brown adipose
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Silva, Elga Batista da, Marcela Cristina Machado Raposo, Michele Matias da Conceição, and Vanessa De Oliveira dos Santos. "Capacidade antioxidante de frutas e hortaliças." Revista Verde de Agroecologia e Desenvolvimento Sustentável 10, no. 5 (2015): 93. http://dx.doi.org/10.18378/rvads.v10i5.3636.

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<p>A definição de alimentos funcionais ainda é controversa na literatura, são definidos como aqueles que apresentam concentrações de um ou mais ingredientes modificados ou manipulados para melhorar sua contribuição para dieta saudável. Esses alimentos apresentam ainda nutrientes em quantidades apreciáveis, como é o caso das frutas e hortaliças que apresentam em sua composição compostos antioxidantes capazes de combater os radicais livres. Objetivou-se com essa revisão bibliográfica discutir os benefícios dos compostos com atividade antioxidantes presentes em frutas e hortaliças. Este est
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Sureshkumar, Kshirsagar Shubhangi, Anjali D. Turale, Mangesh Hedau, and Ashish Jaiswal. "ROLE OF AMALAKI RASAYAN AS AN ANTIOXIDANT IN OXIDATIVE STRESS." International Ayurvedic Medical Journal 9, no. 10 (2021): 2486–89. http://dx.doi.org/10.46607/iamj3009102021.

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Ayurveda is the science of life. The main aim of Ayurveda is to maintain the health of a healthy person and to cure the diseased person. For the maintenance of the health of a healthy person, rasayan chikitsa is advised in Ayurve- da. Rasayan chikitsa is the separate branch of Ayurveda, which deals with various aspects of preventive health care. In today’s modern era, the incidence of lifestyle disorders like hypertension, obesity, diabetes mellitus and cardiovascular diseases increased, because of altered dietary and living patterns. Oxidative stress may be respon- sible for most of the disea
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Naghii, M. R. "A Suggested Method for the Prediction of the Oxidation Resistance of Low Density Lipoprotein by Determination of the Lag Time." Nutrition and Health 16, no. 2 (2002): 107–12. http://dx.doi.org/10.1177/026010600201600204.

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A simple clinical blood test, which measures the total antioxidant status of Low Density Lipoprotein (LDL) and therefore its vulnerability to oxidative stress is suggested, and as a first stage this was tried on a small sample of eight healthy adult males. The body's natural defence and repair systems try to handle all free radicals, but these systems are not hundred percent effective. Thereby, the role of antioxidants (particularly natural antioxidants) becomes evident and vitamins such as Vitamin C, Vitamin E, and compounds like beta-carotene are under especially extensive study. Vitamin C i
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Hosseinabadi, Majid Bagheri, Narges Khanjani, Pirasteh Norouzi, Mehdi Mirzaii, Jamal Biganeh, and Freshteh Nazarkhani. "Investigating the effects of vitamins E and C on oxidative stress and hematological parameters among power plant workers: A double-blind randomized controlled clinical trial." Toxicology and Industrial Health 36, no. 2 (2020): 99–109. http://dx.doi.org/10.1177/0748233720908993.

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The present study aimed to determine the effect of taking antioxidant vitamins including vitamins E and C in reducing oxidative stress levels and improving blood parameters. This double-blind randomized controlled trial study was conducted among the employees working in different parts of a power plant in Semnan, Iran, in 2017. A total of 91 employees were randomly allocated to four groups including vitamin E (400 units per day), vitamin C (1000 mg per day), vitamin E + C for 90 days, and control. The levels of malondialdehyde (MDA), superoxide dismutase (SOD), catalase (Cat), and total antiox
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Ramnath, Shubharani, and Sivaram Venkataramegowda. "Antioxidant Activity of Indian Propolis - An In Vitro Evaluation." International Journal of Pharmacology, Phytochemistry and Ethnomedicine 5 (October 2016): 79–85. http://dx.doi.org/10.18052/www.scipress.com/ijppe.5.79.

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Antioxidants from the natural products are essential to prevent the progression of free radical mediated diseases. In the present study, ethanol extract of propolis collected from different geographical origin were evaluated for their free radical scavenging potential by employing different in-vitro assays such as DPPH, ABTS, Nitric oxide and Hydrogen peroxide. All the tested samples contained considerable amount of total phenols and vitamin C content. In the entire assay, the percentage of inhibition increased with the increase in concentration. Among the propolis samples collected, the highe
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Balakrishnan, Brindha Banu, and Kalaivani Krishnasamy. "EVALUATION OF FREE RADICAL SCREENING AND ANTIOXIDANT POTENTIAL OF MORINGA CONCANENSIS NIMMO-A MEDICINAL PLANT USED IN INDIAN TRADITIONAL MEDICATION SYSTEM." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 7 (2018): 91. http://dx.doi.org/10.22159/ijpps.2018v10i7.26403.

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Objective: We aimed to investigate the free radical scavenging, antioxidant and hepatoprotective potential of M. concanensis Nimmo leaves.Methods: Free radical scavenging activity was evaluated by employing various accepted in vitro­ systems, such as 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS), hydroxyl (OH) and nitric oxide (NO) radical. Antioxidant potential of M. concanensis Nimmo extract was assessed against H2O2 in goat liver by determination of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione S-
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Qasim, Nimra, Muhammad Shahid, Fatima Yousaf, et al. "Therapeutic Potential of Selected Varieties of Phoenix Dactylifera L. Against Microbial Biofilm and Free Radical Damage to DNA." Dose-Response 18, no. 4 (2020): 155932582096260. http://dx.doi.org/10.1177/1559325820962609.

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Phoenix dactylifera L. (Date palm) is the most widely consumed fruit around the world and is rich source of nutrients containing dietary fibers, minerals, vitamins, sugar, protein and antioxidants with potent bioactivities against various microbial pathogens. This study evaluated the therapeutic potential of 2 varieties of ethanolic extracts of Phoenix dactylifera i-e Ajwa and Khalas against bacterial biofilms. This study also investigated the protective effect of Ajwa and Khalas against hydroxyl radical damage to calf thymus DNA. Antioxidant potential through different antioxidant assays show
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Liakopoulos, Vassilios, Stefanos Roumeliotis, Andreas Bozikas, Theodoros Eleftheriadis, and Evangelia Dounousi. "Antioxidant Supplementation in Renal Replacement Therapy Patients: Is There Evidence?" Oxidative Medicine and Cellular Longevity 2019 (January 15, 2019): 1–23. http://dx.doi.org/10.1155/2019/9109473.

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The disruption of balance between production of reactive oxygen species and antioxidant systems in favor of the oxidants is termed oxidative stress (OS). To counteract the damaging effects of prooxidant free radicals, all aerobic organisms have antioxidant defense mechanisms that are aimed at neutralizing the circulating oxidants and repair the resulting injuries. Antioxidants are either endogenous (the natural defense mechanisms produced by the human body) or exogenous, found in supplements and foods. OS is present at the early stages of chronic kidney disease, augments progressively with ren
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Ureta, Romnick, Siegfred Mejico, and Yvonne Maranan. "Free Radical Scavenging Activity and Antioxidants of Hydrocotyle vulgaris L. (Pennywort): Baseline Study in Developing Biocosmetic-Antidote for Pathological Aging." International Journal of Pharmacology, Phytochemistry and Ethnomedicine 10 (July 2018): 1–12. http://dx.doi.org/10.18052/www.scipress.com/ijppe.10.1.

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Pathological aging due to harmful free radicals and oxidative stress has been a serious threat to human health (Kensella & He, 2008). Thus, the study aimed to evaluate the free radical scavenging activity, antioxidants, essential vitamins, and physicochemical properties of Hydrocotyle vulgaris L. (Pennywort) which could serve as basis in developing a biocosmetic antidote for pathological aging. H.vulgaris L. plant was harvested, air dried and then extracted via soxhlet. UV-vis spectroscopy was used for scavenging activity and antioxidants of the plant while High Performance Liquid Chromato
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Zulaikhah, Siti Thomas. "The Role of Antioxidant to Prevent Free Radicals in The Body." Sains Medika 8, no. 1 (2017): 39. http://dx.doi.org/10.26532/sainsmed.v8i1.1012.

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AbstractAntioxidants are compounds that can counteract or reduce the negative impact oxidants in the body. Antioxidants work by donating an electron to compounds that are oxidant so that the oxidant compound activity can be inhibited. Antioxidants are classified into two, namely antioxidant enzymes and non-enzyme. Antioxidant enzymes as enzyme superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), a non-enzyme antioxidant found in many vegetables and fruits, which include reduced glutathione (GSH), vitamin C, E, β- carotene, flavonoids, isoflavones, flavones, antosionin,
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Onyema-iloh, Bridget Obiageli, Samuel C. Meludu, Emmanuel Iloh, Johnkennedy Nnodim, Onyema Onyegbule, and Blessing Mykembata. "Biochemical changes in some trace elements, antioxidant vitamins and their therapeutic importance in prostate cancer patients." Asian Journal of Medical Sciences 6, no. 1 (2014): 95–97. http://dx.doi.org/10.3126/ajms.v6i1.10799.

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Aim: This study was conducted to evaluate the serum levels of some trace-elements (zinc, copper and selenium) and antioxidant vitamins (vitamin A, C and E) in prostate cancer patients. Method: A total of 50 prostate cancer patients aged 50-70 years with PSA > 4.0 ng/dl were recruited for the study while 50 apparently healthy individual were used as control subjects. Zinc, copper and selenium were determined using atomic absorption spectrophotometer while vitamin A, C and E were determined using high performance liquid chromatography. Result: The result showed that the mean levels of Se (0.7
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Grundman, Michael, and Patrick Delaney. "Antioxidant strategies for Alzheimer's disease." Proceedings of the Nutrition Society 61, no. 2 (2002): 191–202. http://dx.doi.org/10.1079/pns2002146.

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Oxidative damage is present within the brains of patients with Alzheimer's disease (AD), and is observed within every class of biomolecule, including nucleic acids, proteins, lipids and carbohydrates. Oxidative injury may develop secondary to excessive oxidative stress resulting from β-amyloid-induced free radicals, mitochondrial abnormalities, inadequate energy supply, inflammation or altered antioxidant defences. Treatment with antioxidants is a promising approach for slowing disease progression to the extent that oxidative damage may be responsible for the cognitive and functional decline o
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Riccioni, D’Orazio, Salvatore, Franceschelli, Pesce, and Speranza. "Carotenoids and Vitamins C and E in the Prevention of Cardiovascular Disease." International Journal for Vitamin and Nutrition Research 82, no. 1 (2012): 15–26. http://dx.doi.org/10.1024/0300-9831/a000090.

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Atherosclerotic cardiovascular diseases (CVD) are a major source of mortality and morbidity in the general population. Oxidative modification of low-density lipoprotein cholesterol (LDL-C) represents the most important determinant factor in the development and progression of atherosclerotic lesions. Oxidative damage and the production of free radicals (FRs) in the endothelium are some of the main factors involved in the pathogenesis of the atherosclerotic process that causes CVD. Appropriate nutritional practices are of central importance in managing risk and treatment of CVD; in fact, many cu
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Mardiyah, Siti. "Uji Antioksidan Belimbing Wuluh dan Ampas Nanas Terhadap Kualitas Minyak Goreng Habis Pakai." JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST 4, no. 1 (2021): 88. http://dx.doi.org/10.30651/jmlt.v4i1.7509.

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Anti-Oxidant Tests of starfruit and pineapple pulp on the quality of Used Cooking Oils ABSTRACTUsed Cooking Oil is oil produced from frying residue and is carcinogenic because it causes oxidation, hydrolysis, and polymerization to produce toxic peroxides and free fatty acids that are difficult for the body to digest. Measurement of oil quality can be measured through 3 parameters, namely, the peroxide number, the acid number and the oil color. Efforts to control the quality of cooking oil are the addition of natural antioxidants, starch wuluh and pineapple pulp. Starfruit contains flavonoids,
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Zocoler, Analice Martins Daleffi, Andréia Cristina Conegero Sanches, Ingrid Albrecht, and João Carlos Palazzo de Mello. "Antioxidant capacity of extracts and isolated compounds from Stryphnodendron obovatum Benth." Brazilian Journal of Pharmaceutical Sciences 45, no. 3 (2009): 443–52. http://dx.doi.org/10.1590/s1984-82502009000300009.

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The extract from stem bark of Stryphnodendron obovatum Benth. was chromatographed on a Sephadex® LH-20 column, and yielded nine compounds: gallic acid (GA), p-hydroxybenzoic acid (PHB), gallocatechin (GC), epigallocatechin (EPG), 4'-O-methylgallocatechin (MGC), epigallocatechin-(4β→8)-epigallocatechin (EPEP), epigallocatechin-(4β→8)-gallocatechin (EPGC), robinetinidol-(4α→8)-gallocatechin (ROGC) and robinetinidol-(4β→8)-epigallocatechin (ROEP). Evaluation of the antioxidant capacity in vitro by the methods of DPPH free radical (IC50; μg/mL) and reduction of the phosphomolybdenum complex (RAC)
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Gackowski, D., M. Ciecierski, A. Jawień, and R. Oliński. "Background level of 8-oxo-2'-deoxyguanosine in lymphocyte DNA does not correlate with the concentration of antioxidant vitamins in blood plasma." Acta Biochimica Polonica 48, no. 2 (2001): 535–39. http://dx.doi.org/10.18388/abp.2001_3936.

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Antioxidant vitamins, being effective free radical scavengers, can protect cellular DNA from oxidative damage. Therefore, in the present study we report on the relationship between basal level of 8-oxo-2'-deoxyguanosine in human lymphocyte DNA and the concentration of antioxidant vitamins (A, C and E). The average level of 8-oxo-2'-deoxyguanosine in lymphocytes of the studied group (15 males and 20 females) was 9.57 per 10(6) dG molecules. The endogenous level of ascorbic acid (vitamin C) in the plasma was, on average, 56.78 microM, while the mean concentrations of retinol (vitamin A) and alph
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35

Madhikarmi, Nirjala Laxmi, Shambhu Kumar Panjijyar, and Madhav Gautam. "Type 2 Diabetes Mellitus: The Role of Oxidative stress and Antioxidants." International Journal of Human and Health Sciences (IJHHS) 5, no. 4 (2021): 454. http://dx.doi.org/10.31344/ijhhs.v5i4.356.

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Objective: Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia. Oxidative stress contributes to the pathogenesis of diabetic microvascular and macrovascular complications. This study was undertaken to find the oxidative stress and antioxidant conditions in diabetic and healthy individuals.Method: A case-control study was carried out at Kantipur Dental College Teaching Hospital & Research center, Kathmandu, Nepal from January 2018 to January 2019 with 200 subjects. Amongst them 100 were diagnosed as diabetic individuals and rest 100 were healthy controls with ag
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36

Dobriyan, E. I. "Dairy antioxidant system." Proceedings of the Voronezh State University of Engineering Technologies 82, no. 2 (2020): 101–6. http://dx.doi.org/10.20914/2310-1202-2020-2-101-106.

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A review of dairy antioxidants was done based on local and international sources. Oxidative processes of fat are the main cause of chemical spoilage of milk and dairy products. Lipid oxidation is associated mainly with the amount of unsaturated fatty acids in the shells of fat globules and plasma phospholipids, as well as with the amount of free fat. The products of oxidative reactions at different stages of lipid oxidation with atmospheric oxygen are fatty acid hydroperoxides, peroxides, aldehydes, ketones, hydroxy acidswhich not only worsen the organoleptic characteristics of milk, but some
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Lesgards, Jean-Francois, Marie-Pascale Lehucher-Michel, Nicolas Vidal, and Pierre Stocker. "Assessment of Antioxidative Activity of Lipid- and Water-Soluble Vitamins in Human Whole Blood. Comparative Analysis Between a Biological Test and Chemical Methods." International Journal for Vitamin and Nutrition Research 75, no. 1 (2005): 11–18. http://dx.doi.org/10.1024/0300-9831.75.1.11.

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Assessment of the antioxidant activity of vitamins and other compounds is of interest in the understanding of their in vivo effects. In this study, we have investigated the activity of several lipid and water-soluble vitamins in human whole blood. Measurements were carried out using a biological test that enables the evaluation of both red blood cells and plasma resistance against free radical activity induced by 2,2'-azobis (2-amidinopropane)hydrochloride (AAPH). Antioxidant activity of vitamins has been determined by using the biological test versus chemical methods (chemiluminescence, DMPD
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38

P., Yashaswini, Geetha A., and Ravi K. "A comparative study of efficacy and safety of anti-oxidants as an add-on therapy to metformin on glycemic parameters in newly diagnosed type 2 diabetes mellitus patients at a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 10, no. 8 (2021): 925. http://dx.doi.org/10.18203/2319-2003.ijbcp20212919.

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Background: Oxidative stress plays major role in diabetes mellitus (DM), abnormal high free radicals decline antioxidant defence mechanism can lead to damage of cellular organelles and enzymes, increased lipid peroxidation and insulin resistance leads to development of complications. Supplementation of antioxidants protects free radical induced damage and further complications. The objective was to evaluate the efficacy and safety of metformin versus metformin with vitamin C and E on glycaemic parameters in newly diagnosed type 2 diabetes mellitus (T2DM).Methods: 60 newly diagnosed T2DM patien
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Cefali, Letícia Caramori, Ludmila de Oliveira Maia, Rebeca Stahlschimidt, et al. "Vitamin C in Acerola and Red Plum Extracts: Quantification via HPLC, in Vitro Antioxidant Activity, and Stability of their Gel and Emulsion Formulations." Journal of AOAC INTERNATIONAL 101, no. 5 (2018): 1461–65. http://dx.doi.org/10.5740/jaoacint.18-0008.

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Abstract Background: The fruits acerola and red plum are known to be good sources of antioxidants, particularly vitamin C. Antioxidants are compounds that protect organisms from biomolecular damage, such as accelerated aging, caused by free radicals. Objective: The objective of this study was to extract vitamin C from acerola and red plum, incorporate these extracts into different topical formulations, and evaluate the physicochemical stabilities of these formulations under stress conditions. Methods: Vitamin C was extracted from acerola and red plum via dynamic maceration for 2 h at 50 ± 2°C
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Johnson, Uyovwiesevwa Ataihire, Eze Kingsley Nwangwa, and John Chukwuka Igweh. "Anti-Oxidant Effects of Silybum marianum Extracts on Diabetic Wistar Rats." Journal of Medical Research 5, no. 4 (2019): 145–50. http://dx.doi.org/10.31254/jmr.2019.5403.

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Antioxidants are specialized macro-molecules that neutralize harmful substances; free radicals. These radicals supposedly harm tissues, destroy food items, and damage materials. In living organisms, antioxidants can take the form of enzymes, and may be regularly added to oils, metals, foodstuffs, as well as numerous other materials to mitigate the damaging effect of free radical. Current study was designed to investigate the biochemical changes in antioxidant enzyme activities, following administration of Silybum marianum (an ancient medicinal plant of the Carduus marianum family) on Alloxan-I
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Khojah, Hani MJ, and Sameh A. Ahmed. "Comparative assessment of individual RONS in serum of smokers compared with non-smokers and their correlation with the lipid profile and antioxidant status." Journal of International Medical Research 47, no. 12 (2019): 6223–34. http://dx.doi.org/10.1177/0300060519882563.

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Objective Cigarette smoking generates free radicals, such as reactive oxygen and nitrogen species (RONS) that contribute to many diseases. The aim of this study was to compare the levels of individual RONS in serum from smokers and non-smokers, and to examine their impact on lipid profiles and the endogenous antioxidant status, which is represented by vitamins C and E. Methods Ninety-four healthy Egyptian volunteers (48 smokers and 46 non-smokers) were enrolled. Blood samples were collected and analysed for common haematological tests, lipid profiles, and serum antioxidants. Six reactive oxyge
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Muslim, Zulfahmi, Aris Prasetyo, and Septa Surya Wahyudi. "Pengaruh Vitamin C terhadap Fragilitas Osmotik Eritrosit pada Mahasiswa Kedokteran Universitas Jember yang Mengalami Stres Psikologis." Pustaka Kesehatan 7, no. 1 (2020): 14. http://dx.doi.org/10.19184/pk.v7i1.17585.

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Medical students are constantly getting stress that could lead to oxidative stress where the level of free radicals is higher than the level of antioxidants in the body. Free radicals can bind to erythrocyte membranes and alter membrane structure that lead to the integrity of the erythrocyte membrane resulting in decreased erythrocyte ability in preventing hemolysis. Vitamin C is an antioxidant that could prevent free radicals bond to erythrocyte membrane. Vitamin C works by donating electrons to free radicals and prevent binding to erythrocyte membranes. The purposed of this study was to dete
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Chibuzo, Carole Nweze, Abdurrasheed Yusuf Hauwa, and Ahmed Zubairu. "Comparative Study on Phytochemical Composition and In Vitro Radical Scavenging Activity of Ethanolic Extracts of Landolphia lanceolata and Nutraceutical-C24/7." International Journal of Pharmacology, Phytochemistry and Ethnomedicine 10 (July 2018): 36–44. http://dx.doi.org/10.18052/www.scipress.com/ijppe.10.36.

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This study investigated the phytochemical composition andin-vitroradical scavenging activity of ethanolic extracts of Nutraceutical-C24/7 andLandolphialanceolatafruit. Phytochemical screening ofLandolphialanceolatafruit extractindicated the presence of phenols, flavonoids, saponins, alkaloids, terpenoids, tannins, triterpenoids and steroids. While nutraceutical-C24/7 showed precence of with exception of saponins, terpenoids and triterpenoids. Some of the identified Phytochemicals and vitamins concentrations quantified were higher inLandolphialanceolatafruit extractthan nutraceutical-C24/7 with
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Kumar, Vinay, Ahmed Abdullah Khan, Anu Tripathi, Praveen K. Dixit, and U. K. Bajaj. "Role of oxidative stress in various diseases: Relevance of dietary antioxidants." Journal of Phytopharmacology 4, no. 2 (2015): 126–32. http://dx.doi.org/10.31254/phyto.2015.4213.

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Oxidative stress plays important role in the pathophysiology of various diseases. Oxidative stress is caused in body due to an imbalance between the activities of endogenous pro-oxidative enzymes. Cellular antioxidants are known to change their redox state and they can be targeted for destruction, regulate oxidative processes involved signal transduction, effect gene expression and the pathways of cell proliferation and death. Oxidants and antioxidants play an important role in maintaining a balance between free radicals produced by metabolism or derived from environmental sources and the anti
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Singh, Poornima, Virginia Paul, and Ritu Dubey. "Antioxidant Foods." International Journal of Advances in Agricultural Science and Technology 9, no. 4 (2022): 1–7. http://dx.doi.org/10.47856/ijaast.2022.v09i04.001.

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Antioxidant is any substance that delays, prevents or removes oxidative damage to a target molecule. It can be found in many foods, including fruits and vegetables. The role of antioxidants in foods is to retard or control oxidation. The process of autoxidation and development of rancidity in foods involves a free radical chain mechanism via initiation, propagation and termination steps. While radicals are produced in the ‘initiation’ step, they react with unsaturated fatty acids by abstracting a hydrogen atom from a site which requires the least energy that is the allylic or diallylic positio
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46

Kumar, Vinoth, Malliga Elangovan, and Raja Sekar Srinivasan. "Enzymatic and non-enzymatic antioxidant activity of Pergularia tomentosa against carbon tetra chloride induced hepatic damage in Wistar albino rats." Journal of Microbiology and Biotechnology Research 7, no. 6 (2017): 1. http://dx.doi.org/10.24896/jmbr.2017761.

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Many oxidative stress related disease are due to accumulation of free radicals in the body which causes cell injury. In this study, the enzymatic antioxidants (Superoxide dismutase, Catalase, Glutathione-s-transferase, Glutathione peroxidase, Ascorbate oxidase and Polyphenoloxidase) and non-enzymatic antioxidants (Total reduced glutathione and Vitamin C) activities were determined using Carbon tetrachloride (CCl4) rat liver as experimental model. The ethanol and chloroform extract showed noticeable increases in enzymatic antioxidant and non- enzymatic antioxidant and thus capability to scaveng
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47

Maxwell, S. R. J., H. Thomason, D. Sandler, et al. "Poor Glycaemic Control is Associated with Reduced Serum Free Radical Scavenging (Antioxidant) Activity in Non-Insulin-Dependent Diabetes Mellitus." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 34, no. 6 (1997): 638–44. http://dx.doi.org/10.1177/000456329703400607.

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The diabetic patient is at significantly increased risk of developing vascular disease. Its aetiology may involve oxidative damage by free radicals and protection against such damage can be offered by radical-scavenging antioxidants. We investigated whether there was a relationship between glycaemic control as assessed by measurement of glycated haemoglobin (HbAlc) and serum antioxidant status in a population of 118 diabetic outpatients with either insulin-dependent or non-insulin-dependent diabetes. Amongst patients with non-insulin-dependent diabetes mellitus there was a significant inverse
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48

Marwicka, Justyna, and Anna Zięba. "Antioxidants as a defence against reactive oxygen species." Aesthetic Cosmetology and Medicine 10, no. 6 (2021): 271–76. http://dx.doi.org/10.52336/acm.2021.10.6.02.

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Reactive oxygen species are formed as a natural product of metabolic processes occurring in the organism or under the influence of external factors. Under homeostasis, they play an important role as a cellular signaling device. During oxidative stress, when they are produced in excess, they can cause damages to proteins, lipids, carbohydrates or nucleic acids. Exposure of cells and extracellular structures to free radicals activate natural mechanisms to eliminate free radicals and their derivatives. The aim of the article was to present what antioxidants are, and how they protect cells against
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Kumar, Ch Ravi S., Anjali Jha, and Sri Deepthi. "DFT Studies of Distinct Anilines with p-Hydroxycinnamic Acids for Antioxidant Profile." Medicinal Chemistry 17, no. 1 (2020): 60–70. http://dx.doi.org/10.2174/1573406416666200506085152.

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Background: Life style and jobs in current situations have generated increased free radicals such as hydroxyl (OH•) and superoxide (O2•) radicals, thereby increasing stress in humans. Interest in search of antioxidants that trap these free radicals has increased to relieve stress. β-carotene (provitamin A), ascorbic acid (vitamin C), tocopherol or vitamin E, Trolox; butyl hydroxy toluene and phenolic compounds are the well-known antioxidants. Several methods evaluate the antioxidant property existing in natural substances (medicinal plants and agri-food products) and synthetic compounds (2-met
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Kiokias, Sotirios, Charalampos Proestos, and Vassilki Oreopoulou. "Effect of Natural Food Antioxidants against LDL and DNA Oxidative Changes." Antioxidants 7, no. 10 (2018): 133. http://dx.doi.org/10.3390/antiox7100133.

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Radical oxygen species formed in human tissue cells by many endogenous and exogenous pathways cause extensive oxidative damage which has been linked to various human diseases. This review paper provides an overview of lipid peroxidation and focuses on the free radicals-initiated processes of low-density lipoprotein (LDL) oxidative modification and DNA oxidative damage, which are widely associated with the initiation and development of atherosclerosis and carcinogenesis, respectively. The article subsequently provides an overview of the recent human trials or even in vitro investigations on the
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