Relevant bibliographies by topics / Antiprotozoal

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Antiprotozoal'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "Antiprotozoal"

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Semenova, Yuliya, Assiya Kussainova, Laura Kassym, Ainur Aimurziyeva, Daniil Semenov, and Lisa Lim. "Consumption Trends of Antifungal and Antiprotozoal Agents for Human Systemic Use in Kazakhstan from 2017 to 2023." Antibiotics 13, no. 9 (2024): 857. http://dx.doi.org/10.3390/antibiotics13090857.

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Background/Objectives: While multiple studies have investigated antibiotic consumption rates, there are few studies on the consumption of systemic antifungals and antiprotozoals. This study aims to fill this gap by providing a comprehensive analysis of nationwide consumption trends in Kazakhstan over a seven-year period (2017–2023). Methods: Defined daily doses per 1000 inhabitants per day were calculated for systemic antifungals (J02 code of the Anatomical Therapeutic Chemical Classification System (ATC)) and antiprotozoals (P01 code of the ATC). Time series analyses were applied to examine h
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Rodríguez-Villar, Karen, Lilián Yépez-Mulia, Miguel Cortés-Gines, et al. "Synthesis, Antiprotozoal Activity, and Cheminformatic Analysis of 2-Phenyl-2H-Indazole Derivatives." Molecules 26, no. 8 (2021): 2145. http://dx.doi.org/10.3390/molecules26082145.

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Indazole is an important scaffold in medicinal chemistry. At present, the progress on synthetic methodologies has allowed the preparation of several new indazole derivatives with interesting pharmacological properties. Particularly, the antiprotozoal activity of indazole derivatives have been recently reported. Herein, a series of 22 indazole derivatives was synthesized and studied as antiprotozoals. The 2-phenyl-2H-indazole scaffold was accessed by a one-pot procedure, which includes a combination of ultrasound synthesis under neat conditions as well as Cadogan’s cyclization. Moreover, some c
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Salem, Manar M., and Karl A. Werbovetz. "Antiprotozoal Compounds fromPsorothamnuspolydenius." Journal of Natural Products 68, no. 1 (2005): 108–11. http://dx.doi.org/10.1021/np049682k.

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Dembitsky, Valery M., Ekaterina Ermolenko, Nick Savidov, Tatyana A. Gloriozova, and Vladimir V. Poroikov. "Antiprotozoal and Antitumor Activity of Natural Polycyclic Endoperoxides: Origin, Structures and Biological Activity." Molecules 26, no. 3 (2021): 686. http://dx.doi.org/10.3390/molecules26030686.

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Polycyclic endoperoxides are rare natural metabolites found and isolated in plants, fungi, and marine invertebrates. The purpose of this review is a comparative analysis of the pharmacological potential of these natural products. According to PASS (Prediction of Activity Spectra for Substances) estimates, they are more likely to exhibit antiprotozoal and antitumor properties. Some of them are now widely used in clinical medicine. All polycyclic endoperoxides presented in this article demonstrate antiprotozoal activity and can be divided into three groups. The third group includes endoperoxides
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Osipov, Alexey V., Elena G. Cheremnykh, Rustam H. Ziganshin та ін. "The Potassium Channel Blocker β-Bungarotoxin from the Krait Bungarus multicinctus Venom Manifests Antiprotozoal Activity". Biomedicines 11, № 4 (2023): 1115. http://dx.doi.org/10.3390/biomedicines11041115.

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Protozoal infections are a world-wide problem. The toxicity and somewhat low effectiveness of the existing drugs require the search for new ways of protozoa suppression. Snake venom contains structurally diverse components manifesting antiprotozoal activity; for example, those in cobra venom are cytotoxins. In this work, we aimed to characterize a novel antiprotozoal component(s) in the Bungarus multicinctus krait venom using the ciliate Tetrahymena pyriformis as a model organism. To determine the toxicity of the substances under study, surviving ciliates were registered automatically by an or
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Khaw, M., and C. B. Panosian. "Human antiprotozoal therapy: past, present, and future." Clinical Microbiology Reviews 8, no. 3 (1995): 427–39. http://dx.doi.org/10.1128/cmr.8.3.427.

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Human protozoal infections are ubiquitous and occur worldwide. In many cases, antiprotozoal agents currently in use predate the modern antibiotic era. Despite the relative lag in development of new antiprotozoal agents, the 1990s have witnessed an increasing level of interest in these infections, inspired by international travel and immigration, a growing awareness of antiprotozoal drug resistance, and the significance of acute and recrudescent protozoal infections in immunosuppressed hosts. This review summarizes for nonclinician readers the past, present, and future therapies for common huma
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Graebin, C., F. Uchoa, L. Bernardes, V. Campo, I. Carvalho, and V. Eifler-Lima. "Antiprotozoal Agents: An Overview." Anti-Infective Agents in Medicinal Chemistry 8, no. 4 (2009): 345–66. http://dx.doi.org/10.2174/187152109789760199.

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Chibale, Kelly. "Towards broadspectrum antiprotozoal agents." Arkivoc 2002, no. 9 (2003): 93–98. http://dx.doi.org/10.3998/ark.5550190.0003.910.

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Oketch-Rabah, H. A., S. F. Dossaji, S. Brøgger Christensen, et al. "Antiprotozoal Compounds fromAsparagus africanus." Journal of Natural Products 60, no. 10 (1997): 1017–22. http://dx.doi.org/10.1021/np970217f.

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Hoji, Kazuhiko. "Workshop summary: Antiprotozoal resistance." Veterinary Parasitology 64, no. 1-2 (1996): 133–34. http://dx.doi.org/10.1016/0304-4017(96)00980-6.

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Dissertations / Theses on the topic "Antiprotozoal"

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Ganto, Mlungiseleli Macdonald. "Antiprotozoal quinolines containing electrophilic moieties." Master's thesis, University of Cape Town, 2004. http://hdl.handle.net/11427/6307.

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Includes bibliographical references.<br>Compounds containing the quinoline moiety have been the mainstay of antimalarial chemotherapy. However, the emergence of resistant strains of Plasmodium falciparum, the causative agent of malaria, has compromised the efficacy of these antimalarial quinolines. Therefore the development of new efficient drugs is of critical importance. Extensive research has identified the cysteine proteases in malaria and other parasitic diseases as potential targets for new chemotherapy due to their critical roles in the life cycles of the causative agents. Due to their
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Hardman, Mark Alan. "Design of potential antiprotozoal daunorubicin derivatives." Thesis, De Montfort University, 1985. http://hdl.handle.net/2086/10737.

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Daunorubicin is an antitumour antibiotic which is highly active against the sleeping sickness parasite Trypanosoma rhodesiense in vitro, but which lacks in vivo activity. The object of this work was to modify daunorubicin so as to promote in vivo activity, and to study the mechanism by which daunorubicin is trypanocidal. A series of daunorubicin analogues, and derivatives in which daunorubicin was linked to a macromolecular carrier (known as daunorubicin conjugates) were prepared, and tested against trypanosome infected mice. Only daunorubicin conjugates in which drug was linked to the carrier
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Sola, Lao Irene. "Novel approaches toward anti-Alzheimer and antiprotozoal drug candidates." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/399594.

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This PhD Thesis pursues the development of novel anti-Alzheimer and antiprotozoal drug candidates upon exploitation of three different novel approaches: Multitarget therapies, Drug repurposing, and Validation of a novel anti-malarial target. The work carried out in the frame of this PhD Thesis has followed three research lines, thus dividing the next report on three main objectives, namely the development of novel diseasemodifying anti‐Alzheimer agents, novel potential 4-aminoquinoline-based anti tripanosomatid compounds, and so far unexplored substrate analog PfG6PD inhibitors for the trea
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Anao, Ivie Isimeme. "Studies on the antiprotozoal activity of some plant species." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423017.

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au, pmenon1@optusnet com, and Kathleen Ilona Menon. "Assessment of the Antiprotozoal Activity of some Tubulin Inhibitors Following Cyclodextrin Complexation." Murdoch University, 2002. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20040820.133836.

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The purpose of the present study was to evaluate the potential usefulness of tubulin inhibitors when complexed with hydroxypropyl-â-cyclodextrin (ÇPâCD) against a range of protozoan parasites. This approach involved investigations into the complexation of these drugs with ÇPâCD, and subsequent investigations of these drugs and their complexes in regard to cytotoxicity, pharmacokinetics, in vitro efficacy against Giardia, Cryptosporidium and rodent malaria (Plasmodium chabaudi), and their in vivo efficacy against Giardia and malaria. Albendazole (ABZ) is a benzimidazole carbamate with a broad
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Menon, Kathleen Ilona. "Assessment of the antiprotozoal activity of some tubulin inhibitors following cyclodextrin complexation." Menon, Kathleen Ilona (2002) Assessment of the antiprotozoal activity of some tubulin inhibitors following cyclodextrin complexation. PhD thesis, Murdoch University, 2002. http://researchrepository.murdoch.edu.au/201/.

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The purpose of the present study was to evaluate the potential usefulness of tubulin inhibitors when complexed with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) against a range of protozoan parasites. This approach involved investigations into the complexation of these drugs with HP-beta-CD, and subsequent investigations of these drugs and their complexes in regard to cytotoxicity, pharmacokinetics, in vitro efficacy against Giardia, Cryptosporidium and rodent malaria (Plasmodium chabaudi), and their in vivo efficacy against Giardia and malaria. Albendazole (ABZ) is a benzimidazole carbamat
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Menon, Kathleen I. "Assessment of the antiprotozoal activity of some tubulin inhibitors following cyclodextrin complexation." Thesis, Menon, Kathleen I. (2002) Assessment of the antiprotozoal activity of some tubulin inhibitors following cyclodextrin complexation. PhD thesis, Murdoch University, 2002. https://researchrepository.murdoch.edu.au/id/eprint/201/.

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The purpose of the present study was to evaluate the potential usefulness of tubulin inhibitors when complexed with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) against a range of protozoan parasites. This approach involved investigations into the complexation of these drugs with HP-beta-CD, and subsequent investigations of these drugs and their complexes in regard to cytotoxicity, pharmacokinetics, in vitro efficacy against Giardia, Cryptosporidium and rodent malaria (Plasmodium chabaudi), and their in vivo efficacy against Giardia and malaria. Albendazole (ABZ) is a benzimidazole carbamat
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Menon, Kathleen I. "Assessment of the antiprotozoal activity of some tubulin inhibitors following cyclodextrin complexation." Access via Murdoch University Digital Theses Project, 2002. http://wwwlib.murdoch.edu.au/adt/admin/view/adt-MU20040820.133836.

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Thapar, Mita Maini. "Pharmacokinetics and dynamics of Atovaquone and Proguanil (Malarone®) /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-035-4/.

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Siheri, Weam Fathi. "Libyan Propolis : a comprehensive chemical, in vitro biological investigation and metabolomic profiling of antiprotozoal activity." Thesis, University of Strathclyde, 2017. http://digitool.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=28767.

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Propolis (bee-glue) is collected by bees from plants as a defensive substance in response to environmental pressures which include a range of microorganisms and parasites. These parasites are known to include the protozoal species Crithidia. Since it is collected by bees for the specific purpose of providing chemotherapeutic protection this increases the likelihood of finding active compounds in propolis compared with random screening of plants. Twelve samples of Libyan propolis (P1-P12) were collected from different geographic zones of Libya. Ethanolic extracts of the twelve propolis samples
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Books on the topic "Antiprotozoal"

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Vermelho, Alane Beatriz, and Claudiu T. Supuran, eds. Antiprotozoal Drug Development and Delivery. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-06850-8.

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Hardman, Mark Alan. Design of potential antiprotozoal daunorubicin derivatives. Leicester Polytechnic, 1985.

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Hoberg, Eric P. A compendium of chemotherapy: Anthelmintic and antiprotozoal compounds. Oregon State University, 1989.

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Gutiérrez, Rosa Martha Pérez. Handbook of compounds with antiprotozoal activity isolated from plants. Nova Science Publishers, Inc., 2007.

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Organization, World Health, ed. WHO model prescribing information: Drugs used in parasitic diseases. WHO, 1990.

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K, Majumder Hemanta, ed. Drug targets in kinetoplastid parasites. Springer Science+Business Media, 2008.

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A, Abdi Y., ed. Handbook of drugs for tropical parasitic infections. 2nd ed. Taylor & Francis, 1995.

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Antiprotozoal Drug Development and Delivery. Springer International Publishing AG, 2023.

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Vermelho, Alane Beatriz, and Claudiu T. Supuran. Antiprotozoal Drug Development and Delivery. Springer International Publishing AG, 2022.

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Rivera, Norma, ed. Antiprotozoal Drug Discovery: A Challenge That Remains. BENTHAM SCIENCE PUBLISHERS, 2016. http://dx.doi.org/10.2174/97816810832921160101.

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Book chapters on the topic "Antiprotozoal"

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Abbas, Haider, Muhammad Younus, Zahid Fareed, et al. "Antiprotozoal Resistance." In Antiparasitic Drug Resistance in Veterinary Practice. CABI, 2024. http://dx.doi.org/10.1079/9781800622807.0002.

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Stojković, Marija, and Michael Lanzer. "Antiprotozoal Drugs." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-21573-6_16-1.

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Stojković, Marija, and Michael Lanzer. "Antiprotozoal Drugs." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_16.

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Newbold, C. Jamie. "Assessing Antiprotozoal Agents." In In vitro screening of plant resources for extra-nutritional attributes in ruminants: nuclear and related methodologies. Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-3297-3_4.

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Chabala, John C., and Max W. Miller. "Chemistry of Antiprotozoal Agents." In Chemotherapy of Parasitic Diseases. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1233-8_2.

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Edwards, Geoffrey. "Antiprotozoal and Anthelmintic Agents." In Drug Interactions in Infectious Diseases. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-213-7_17.

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Kiang, Tony K. L., Kyle John Wilby, and Mary H. H. Ensom. "Antiprotozoal and Anthelmintic Agents." In Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-72416-4_13.

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Jack, David B. "Pharmacokinetic data on antiprotozoal agents." In Handbook of Clinical Pharmacokinetic Data. Palgrave Macmillan UK, 1992. http://dx.doi.org/10.1007/978-1-349-22495-1_16.

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Franklin, T. J., and G. A. Snow. "Antifungal, antiprotozoal and antiviral agents." In Biochemistry of Antimicrobial Action. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0825-3_6.

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Croft, S. L., and C. R. Weiss. "Natural Products with Antiprotozoal Activity." In Bioassay Methods in Natural Product Research and Drug Development. Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4810-8_7.

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Conference papers on the topic "Antiprotozoal"

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Kilicaslan, OS, M. Kaiser, P. Mäser, et al. "Antiprotozoal activity of compounds isolated from Psychotria leiocarpa." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759106.

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Nejad Ebrahimi, S., H. Hashempour, F. Herfati, et al. "Diterpenoids from Astrodaucus orientalis (L.) Drude - Antiprotozoal activity." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608077.

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Salehi, P., F. Nemati, K. Babanezhad-Harikandei, N. Hadian, M. Bararjanian, and I. Bruno. "Novel noscapine derivatives as potent anticancer and antiprotozoal agents." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399682.

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Rahman, Adeyemi, and Isabel Rozas. "Derivatives of guanidine-based DNA minor groove binders as antiprotozoal agents." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07420.

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Yulistiani, D., E. Wina, I. W. R. Susana, and F. Saputra. "Analysis of bioactive compounds and antioxidant, antibacterial, antiprotozoal activities in tomato plants for livestock." In INTERNATIONAL CONFERENCE ON ORGANIC AND APPLIED CHEMISTRY (ICOAC) 2022. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0184109.

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Kimani, N., J. Matasyoh, M. Kaiser, R. Brun, and T. Schmidt. "ANTIPROTOZOAL SESQUITERPENE LACTONES AND OTHER CONSTITUENTS FROM Schkuhria pinnata, Tarchonanthus camphoratus AND Vernonia lasiopus." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608192.

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Matić, Sanja, Pavle Mašković, and Katarina Šipovac. "DNA PROTECTIVE ACTIVITY OF TWO SPECIES OF THE „SCROPHULARIA“ GENUS 2021ICCBIKG (2021)." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.218m.

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Plants from the genus Scrophularia, family Scrophulariaceae have numerous biological activities such as antibacterial, antioxidant, antiprotozoal, antitumor, hepatoprotective, and antidiabetic. However, as far as we know, genotoxic and antigenotoxic effects of these two plant species remain unexplored. The present study aimed to evaluate possible in vivo protective effects of the methanol extracts of two plant species of the Scrophularia genus, Scrophularia canina L. and S. alata Gilib., against carbon tetrachloride (CCl4)-induced DNA damage in albino Wistar rat. A significant increase in tota
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Gupta, Nehal, та Sanjay Srivastava. "Abstract 2883: Repurposing atovaquone, an antiprotozoal drug for management of breast cancer by inhibiting HER2/β-catenin signaling". У Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2883.

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Szabó, LaraU, Marcel Kaiser, Pascal Mäser, and ThomasJ Schmidt. "Multivariate Data Analysis of LC/MS profiles of Buxus sempervirens L.: Seasonal Variability of Alkaloid profiles and Identification of Antiprotozoal Compounds." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736856.

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Nué-Martínez, J. Jonathan, Ibon Alkorta, and Christophe Dardonville. "Solving a chemical challenge in the synthesis of antiprotozoal agents targeting the DNA minor groove: A high yield synthesis of &lt;em&gt;trans&lt;/em&gt;-azoxybenzene." In 7th International Electronic Conference on Medicinal Chemistry. MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11553.

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