Journal articles: 'Antiradical activity'

1

Karamać, M., A. Buciński, B. Pegg R, and R. Amarowicz. "Antioxidant and antiradical activity of ferulates." Czech Journal of Food Sciences 23, No. 2 (November 15, 2011): 64–68. http://dx.doi.org/10.17221/3373-cjfs.

Full text

Abstract:

Antioxidant and antiradical activities of ferulates (i.e., ferulic acid, isoferulic acid, coniferyl aldehyde, and methyl ferulate) were investigated using a β-carotene-linoleate model system and a DPPH radical scavenging assay, respectively. Compounds so tested exhibited antioxidant and antiradical properties to varying degrees. Methyl ferulate showed the strongest antioxidant activity, whereas the parent phenolic acid was the most active ferulate to scavenge the DPPH radical (DPPH<sup>·</sup>). Isoferulic acid at concentrations ranging from 10 to 100 nmol/assay did not impart an antiradical efficacy; this may be attributed to the location of the hydroxyl group in the meta position on the aromatic ring.  

APA, Harvard, Vancouver, ISO, and other styles

2

Daglia, M., A. Papetti, and G. Gazzani. "Green and roasted coffee antiradical activity stability in chemical systems." Czech Journal of Food Sciences 22, SI - Chem. Reactions in Foods V (January 1, 2004): S191—S194. http://dx.doi.org/10.17221/10658-cjfs.

Full text

Abstract:

The stability to storage at different temperature and oxygen exposure of green and roasted coffee either as coffee beans or as ground coffee antiradical activity, was evaluated. The results showed that the coffee solution antihydroxyl radical activity was constant, independently from the coffee species, from the roasting process, and moreover from the type of storage conditions, suggesting that temperature and oxygen exposure did not affect this antiradical activity. With regard to antiperoxyl radical activity, all green coffee solutions showed remarkable and stable activity. Conversely, the roasted coffee beans and roasted and ground coffee antiperoxyl radical activity started to increase after three month of storage, suggesting that Maillard reaction products affect the stability of such antiradical property.

APA, Harvard, Vancouver, ISO, and other styles

3

Vol’eva, V. B., I. S. Belostotskaya, N. L. Komissarova, A. V. Malkova, T. V. Pokholok, and E. Ya Davydov. "Antiradical activity of dioxolane derivatives." Russian Journal of Organic Chemistry 49, no. 3 (March 2013): 446–49. http://dx.doi.org/10.1134/s1070428013030226.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Vladimirov, Yu A., �. A. Parfenov, O. M. Epanchintseva, and L. D. Smirnov. "Antiradical activity of coumarin ruductones." Bulletin of Experimental Biology and Medicine 112, no. 5 (November 1991): 1560–63. http://dx.doi.org/10.1007/bf00840412.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Lachman, J., M. Šulc, J. Sus, and O. Pavlíková. "Polyphenol content and antiradical activity in different apple varieties." Horticultural Science 33, No. 3 (November 23, 2011): 95–102. http://dx.doi.org/10.17221/3745-hortsci.

Full text

Abstract:

Polyphenols are important antioxidant constituents of apples and they contribute positively to human health because they possess an antiradical activity. Fifteen apple varieties were analysed for their total polyphenol content (TP) by two methods – by Folin-Ciocalteau reagent (FC) and by EBC method with carboxylmethylcellulose/sodium ethylendiamintetraacetate (CMC/EDTA) and their antiradical activity (ARA) by DPPH method using stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH·). TP and ARA were determined in freshly expressed apple juice and apples and obtained results were statistically evaluated. The differences between varieties were significant. The correlation between TP content determined by FC method determining all free aromatic hydroxyls and EBC method determining mainly ortho-aromatic hydroxyls was found with r = 0.73. The highest differences among analysed varieties were found for ARA values in both, juice and apples and for TP content determined by FC in apples. High polyphenol content was found in Jonagold, Jonalord, Melodie and Melrose varieties both, in apples and juices; on the contrary low TP contents were estimated in Gloster and Rosana varieties. The highest ARA levels were found inRajka,Bohemia andMelrose varieties, compared to low ARA levels found in apple fruits of &Scaron;ampion and Topaz varieties.  

APA, Harvard, Vancouver, ISO, and other styles

6

Kaminskiy, Il'ya Petrovich, Yelena Vasil'yevna Yermilova, Tat'yana Vladimirovna Kadyrova, Mariya Sergeyevna Lar'kina, Anton Aleksandrovich D'yakonov, and Mikhail Valer'yevich Belousov. "ANTIRADICAL ACTIVITY OF EXTRACTS FROM SIBERIAN FLORA GENUS CENTAUREA PLANTS." chemistry of plant raw material, no. 4 (December 27, 2019): 173–79. http://dx.doi.org/10.14258/jcprm.2019045409.

Full text

Abstract:

The purpose of this research is to study the antiradical activity of various extracts from the Centaurea scabiosa L. aerial part (wild-growing and cultivated) and Centaurea jacea L. as potential sources of antioxidant herbal remedies. In the study of the antiradical activity of extracts from the aerial part of Centaurea jacea L., Centaurea scabiosa L. wild growing and cultivated, in the reaction with a stable diphenylpicrylhydrazyl radical, it was found that the degree of antiradical activity within each species correlates with the quantitative content of flavonoids. Lower values of the antiradical activity of cultivated Centaurea scabiosa L. extracts compared to wild growing Centaurea scabiosa L. extracts are consistent with a lower content of flavonoids in the latter. The dependence of the Centaurea jacea L. and wild growing Centaurea scabiosa L. extracts antiradical activity on flavonoids quantitative and qualitative composition of these species has been established.

APA, Harvard, Vancouver, ISO, and other styles

7

Zykova, Irina Dement'yevna, Aleksandr Alekseyevich Efremov, and Liliya Viktorovna Naimushina. "ANTIRADICAL ACTIVITY OF SEPARATE FRACTIONS OF ESSENTIAL OIL OF ACORUS CALAMUS ROOTS." chemistry of plant raw material, no. 2 (June 10, 2020): 73–78. http://dx.doi.org/10.14258/jcprm.2020026659.

Full text

Abstract:

Essential oil from the roots of calamus marsh (Acorus calamus L) was isolated by the method of exhaustive hydroparodistillation, growing on the Krasnoyarsk territory. Separate fractions of essential oil were obtained depending on the duration of isolation. The component composition of the essential oil, the main components of which are acorenone, butyrate α-terpineol, germacrene B, camphor. The antiradical properties of the essential oil of A. сalamus roots growing in the Siberian region, as well as the antiradical properties of its individual fractions were studied for the first time in order to determine the most promising samples as sources of biologically active complexes. To determine the antiradical activity, the reaction of the essential oil components with a stable free 2,2-diphenyl-1-picrylhydrazyl radical was used. The antiradical activity of all studied samples of essential oils was established. There was an increase in antiradical activity with a decrease in the content of monoterpenes in the composition of the essential oil. The lowest antiradical activity (17.5%) was shown by the fraction of essential oil with a high content of monoterpenes, the highest (~100%) – fractions with a high content of oxygen-containing compounds. It was revealed that the ability of components of individual fractions of A. сalamus essential oil to inhibit DPPH radicals is comparable with the antiradical activity of ascorbic acid solutions of equivalent concentration.

APA, Harvard, Vancouver, ISO, and other styles

8

L. B. IRISKINA ,, SH. А. МUZDYBAYEVA ,, М. К. ZHAMANBAEVA ,, A. SH. BUKUNOVA,, and G. К. DAUMOVA. "STUDYING OF ANTI-RADICAL PROPERTIES OF PHENOLS AND HETEROCYCLIC AMINES." Bulletin of the National Engineering Academy of the Republic of Kazakhstan 3, no. 77 (October 15, 2020): 119–25. http://dx.doi.org/10.47533/2020.1606-146x.18.

Full text

Abstract:

This work presents the results of studies on the antiradical activity of phenols and heterocyclic amines. The antiradical activity was studied using the reaction of interaction with a stable colored radical by spectrophotometric method. The antiradical activity of natural polyphenol quercetin was studied. The content of quercetin in the dosage form was determined. It was shown that the studied phenols are medium strength inhibitors, and heterocyclic amines exhibit weak inhibitory activity.

APA, Harvard, Vancouver, ISO, and other styles

9

K. Singh, Anil, and Solomon B. Libsu. "Antiradical Activity of β-Ionyl Compounds." Letters in Organic Chemistry 7, no. 4 (June 1, 2010): 338–42. http://dx.doi.org/10.2174/157017810791130603.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Yashin, Alexander, Yakov Yashin, Jing Wang, and Boris Nemzer. "Antioxidant and Antiradical Activity of Coffee." Antioxidants 2, no. 4 (October 15, 2013): 230–45. http://dx.doi.org/10.3390/antiox2040230.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Gataullina, D. R., D. R. Mogilevtseva, G. N. Nugumanova, S. V. Bukharov, R. G. Tagasheva, and R. Ya Deberdeev. "Antiradical activity of benzazole-2-thiones." Russian Journal of General Chemistry 87, no. 9 (September 2017): 1919–23. http://dx.doi.org/10.1134/s1070363217090055.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Avanesyan, A. A., A. N. Pashkov, N. A. Simonyan, A. V. Simonyan, and O. V. Myachina. "Antiradical activity of cinnamic acid derivatives." Pharmaceutical Chemistry Journal 43, no. 5 (May 2009): 249–50. http://dx.doi.org/10.1007/s11094-009-0285-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Ratkin, Ye V., V. V. Ivanov, A. V. Ratkin, and V. S. Chuchalin. "Antioxidant and antiradical properties of polyphenols in the mechanism hepatoprotective actions of preparations Maackia amurensis." Bulletin of Siberian Medicine 10, no. 5 (October 28, 2011): 91–94. http://dx.doi.org/10.20538/1682-0363-2011-5-91-94.

Full text

Abstract:

For finding-out of a role antioxidant and antiradical properties of poly-phenols in mechanisms hepatoprotective actions of preparations from Maackia amurensis activity of preparations from ядровой wood (Macsar), an extract of cellular culture Maackia amurensis, stilbens. Antiradical properties of preparations measured on ability to cooperate with difenilpikrilgidrazilom (DPPH). It is established, that for Macsar, PKMA, monomeasured and dimeric Stilbenes is absent correlations between antiradical activity of the given preparations from a polyphenolic complex Mauck Amur in modelling system with DPPH and them hepatoprotective effect in vivo. Monomeasured and dimeric stilbenes, possessing the highest antiradical activity appreciated on their ability to restore stable radical DPPH, have not shown expressed hepatoprotective activity at a hepatites.

APA, Harvard, Vancouver, ISO, and other styles

14

Zykova, S. S., K. L. Gankova, M. V. Shustov, N. M. Igidov, S. S. Borisevich, and M. G. Ilyina. "Study of Antioxidant Activity and Quantum-chemical Calculations of 2-aminopyrroles." Drug development & registration 11, no. 4 (December 26, 2022): 27–30. http://dx.doi.org/10.33380/2305-2066-2022-11-4(1)-27-30.

Full text

Abstract:

Introduction. Modern therapy defines oxidative stress as one of the key links in the pathogenesis of different diseases, which makes the search for new low molecular weight antioxidants actual [1]. The widely used methods are imperfect, since they reflects reactivity of the sample under artificial conditions [2–4]. The proposed technique of using the "Ecolum" biosensor makes it possible to preserve the advantages of in vitro methods and improve the accuracy of determination through the use of biological reactions of cells [5, 6].Aim. Studying of the antiradical and antioxidant activity of 2-aminopyrroles, using in vitro methods and quantum-chemical calculations. Materials and methods. Earlier, derivatives of 2-aminopyrroles were obtained. Antiradical activity of the compounds was studied using the DPPH test (2,2-diphenyl-1-picrylhydrazyl). Antioxidant activity was evaluated on the model of oxidative stress using the «Ecolum» biosensor. The calculation data of the indices of reactivity in the approximation of the gas phase were obtained using quantum-chemical methods.Results and discussion. The antioxidant activity test indicated a higher antioxidant potential of 2a, compared to 2b. Antiradical activity test revealed a greater antiradical potential of 2b. Quantum-chemical calculations showed that 2b is characterized by a higher ionization potential, which may indicate its greater resistance to oxidation compared to 2a.Conclusion. The study of the antiradical and antioxidant activity of 2-aminopyrroles showed the importance of developing a methodology for the search for new antioxidants, because of antiradical activity test deviations, compared to living cell reactions.

APA, Harvard, Vancouver, ISO, and other styles

15

Polonik, Nikita S., Yuri E. Sabutskii, and Sergey G. Polonik. "Free Radical Scavenging Activity of Synthetic and Naturally Occurring Polyhydroxy-, Aminohydroxynaphthazarins and Related Compounds." Natural Product Communications 13, no. 10 (October 2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301021.

Full text

Abstract:

Fifty natural and synthetic hydroxy-, aminohydroxynaphthazarins and related quinones were tested for their antiradical activities using 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) scavenging assay. The main features of structure-antiradical activity relationship of amino- and hydroxyquinones were determined for the first time. It was found that naphthazarins (5,8-dihydroxy-1,4-naphthoquinones) are much more active against ABTS-radical than related 1,4-naphthoquinones and 5-hydroxy-1,4-naphthoquinones. Natural aminonaphthazarins (spinamine E, echinamine A) and polyhydroxylated naphthazarins (spinazarin, echinochrome, spinochrome D and E) revealed high antiradical properties. In most cases, the presence of long chained O-alkoxy substituent in benzenoid part of naphthazarin core enhanced their antiradical activity.

APA, Harvard, Vancouver, ISO, and other styles

16

Karaulova, Ekaterina P., Anna I. Chepkasova, Tatiana N. Slutskaya, Lidia V. Shulgina, and Eugeny V. Yakush. "Antiradical effect of low-molecular peptides in extracts and hydrolyzates from tissues of water organisms." Izvestiya TINRO 182, no. 3 (September 30, 2015): 269–76. http://dx.doi.org/10.26428/1606-9919-2015-182-269-276.

Full text

Abstract:

Molecular-weight composition of peptides in extracts and hydrolyzates from soft tissues of the clams Corbicula japonica and Mercenaria mercenaria and liver of chum salmon is investigated. Antiradical activity is defined for low-molecular peptides, as well as for high-molecular proteins and free amino acids in the extracts. The maximum activity is detected for the extracts of salmon liver; all protein fractions in the water extract of the liver have antiradical activity. Low-molecular peptides and free amino acids have antiradical activity in all samples. The peptides with molecular weight 4.3 kDa have the highest activity in the water extract from C. japonica (43 units) and the peptides with molecular weight 4.7 kDa - in the water extract from M. mercenaria (5.6 units). After hydrolysis, the portion of low-molecular peptides increases for C. japonica , M. mercenaria , and salmon liver in 22.1, 14.5, and 11.1 %, respectively. Hence antiradical activity for hydrolyzates from C. japonica and M. mercen aria is in 1.9 times higher and for hydrolyzates from salmon liver - in 1.3 times higher than for water extracts from their tissues. Only the peptides with molecular weight 2.8-4.7 kDa have antiradical activity in the hydrolyzates; its value is 1-24 activity units for M. mercenaria ; 13-76 units for C. japonica and about 40 units for the chum salmon liver. Correlation is found between the content of peptides with molecular weight 3-4 kDa in hydrolyzates and their antiradical activity.

APA, Harvard, Vancouver, ISO, and other styles

17

Kocira, Anna. "Biostimulants and the antiradical activity of soybean seeds." BIO Web of Conferences 10 (2018): 01008. http://dx.doi.org/10.1051/bioconf/20181001008.

Full text

Abstract:

In recent years, the interest in the application of biostimulants has increased, which positively affect the growth and development of plants and contribute to an increase in the yield and quality of crops. In Poland, the area of soybean cultivation is constantly increasing and thus the improvement of the quality of its seeds seems to be purposeful. In the available literature, there are few reports regarding the effect of biostimulants on the antiradical activity of plants. Therefore, studies on the influence of biostimulants on soybean seed antiradical activity seem to be justified. The study was carried out in 2014 - 2016 in Perespa, Poland. Annushka soybean seeds were sown in the third decade of April. During the growing season, four biostimulants: Kelpak SL, Terra Sorb Complex, Atonik, and Tytanit, were used in four combinations, using lower or higher concentrations and single or double spraying. After harvesting the plants, the antiradical activity of the seeds was evaluated by ABTS•+ assay. It has been found that the foliar application of biostimulants positively influenced the studied property. The highest antiradical activity of plants was found upon double spraying with lower concentrations of Atonik and Terra Sorb Complex.

APA, Harvard, Vancouver, ISO, and other styles

18

Legzdiņa, Zane, Evita Straumīte, and Zanda Krūma. "Assessment of Bioactive Compounds in Red Wines Available for Purchase in Latvia." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 76, no. 1 (February 1, 2022): 131–37. http://dx.doi.org/10.2478/prolas-2022-0020.

Full text

Abstract:

Abstract Moderate consumption of wine is associated with positive health effects. Red wine contains more polyphenolic compounds than white wine, so it is considered healthier. The aim of the study was to determine the concentration of bioactive compounds of red grape and berry wines available for purchase in Latvia. A selection of 15 red grape and berry wines purchased in Latvian supermarkets were analysed. The total phenol concentration was determined using the Folin-Ciocalteu spectrophotometric method with minor modifications. Total flavonoid concentration was determined using the colorimetric flavonoid determination method. Antiradical activity was determined using the DPPH (2,2-diphenyl-1-picrylhydraziyl) reagent and ABTS (2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonate) radical cation determination method. The results show that the analysed red wine samples can be divided into five clusters according to the concentration of total phenols, flavonoids, and antiradical activity. Cluster 1 separately divided Latvian black chokeberry wine, with high total phenol concentration (TPC) and total flavonoid concentration (TFC), high antiradical activity via the DPPH method, and relatively low antiradical activity via ABTS method. Cluster 4 combined red wines with medium TPC, high TFC and high antiradical activity via both DPPH and ABTS methods, and included grape wines from different countries of origin. Cluster 5 combined red wines with high TPC, medium TFC, and medium antiradical activity via both DPPH and ABTS methods.

APA, Harvard, Vancouver, ISO, and other styles

19

Sabarudin, Ruslin, W. O. S. Zubaydah, A. Sartinah, S. Buton, and Yamin. "Antiradical activity, total phenolic, and total flavonoids extract and fractions of pumpkin (Cucurbita moshata Duch) leaves." Food Research 5, no. 2 (February 13, 2021): 348–53. http://dx.doi.org/10.26656/fr.2017.5(2).529.

Full text

Abstract:

Pumpkin (Cucurbita moshata Duch) is one of the Cucurbitaceae plants, which traditionally used to treat skin diseases, measles, jaundice, insomnia, cancer and enhances endurance. Therefore, it was necessary to explore the potential of pumpkin leaves as antiradical. This research aim was to examine the antiradical activity and total phenolic and total flavonoids of pumpkin leaves extract and its fractions using the DPPH method and determined the phenolic and flavonoid contents. Pumpkin leave powder was extracted with methanol. Furthermore, water was added into methanol extract, and be partitioned using n-hexane and ethyl acetate to obtain n-hexane, ethyl acetate, and water fractions. The antiradical activities of pumpkin leave extract and fractions were determined using DPPH (2,2-diphenyl-1-picryhidrazyl) method. Ethyl acetate fraction obtained higher antiradical activities (IC50 6.737±0.196 µg/mL). Correlation of total phenolic and flavonoid contents to inhibit DPPH radical showed that phenolic and flavonoid contents on pumpkin leaves could be inhibited DPPH radical R2 = 0.8994 and R2 = 0.9061, respectively. Extracts and fraction pumpkin leaves show strong antiradical activity with DPPH methods, so their potential as antiradical can developed and can be used as a functional food.

APA, Harvard, Vancouver, ISO, and other styles

20

Ni, Jiaqi, Lilin Lu, and Yi Liu. "Antiradical and Antioxidative Activity of Azocalix[4]arene Derivatives: Combined Experimental and Theoretical Study." Molecules 24, no. 3 (January 29, 2019): 485. http://dx.doi.org/10.3390/molecules24030485.

Full text

Abstract:

Developing antioxidants with high efficiency is fundamentally important for the protection of living cells and engineering materials against oxidative damage. In this present study, two azocalix[4]arene derivatives were synthesized via a diazo coupling reaction between calix[4]arene and diazonium salts. Their antiradical and antioxidative performances were evaluated by hydroxyl radical scavenging and pyrogallol autoxidation inhibition experiments. Combined with theoretical studies, the antiradical and antioxidative mechanisms have been explored. The results demonstrated that these two azocalix[4]arene derivatives both exhibited remarkable antiradical and antioxidative activity. The macrocyclic framework of the calix[4]arene and para-azo substituent group at the upper rim of calix[4]arene contributed synergistically and importantly to its excellent antiradical and antioxidant activity.

APA, Harvard, Vancouver, ISO, and other styles

21

Belykh, Dmitrii, Lidiya Mazaletskaya, Nataliya Sheludchenko, Tatyana Rocheva, Irina Khudyaeva, Evgeny Buravlev, Olga Shchukina, and Irina Chukicheva. "Antiradical Activity of Porphyrins with a Diisobornylphenol Fragment at the Macrocycle Periphery." Molecules 23, no. 7 (July 14, 2018): 1718. http://dx.doi.org/10.3390/molecules23071718.

Full text

Abstract:

This article focuses on the antiradical activity of a number of 2,6-diisobornylphenol-porphyrin conjugates with various spacers between the porphyrin and phenolic fragments in the model reaction of ethylbenzene oxidation initiated by azoisobutyric acid dinitrile. The study has shown that the electronic effects of the groups directly related to the 2,6-diisobornylphenol fragment exert the predominant influence both on the reactivity of the phenolic hydroxyl group in interaction with free radicals and on the antiradical activity of the molecule as a whole. The antiradical activity of the molecule is generally less affected by the nature of the substituents in the porphyrin macrocycle, mainly due to a change in the stoichiometric inhibition coefficient in the presence of relatively easily oxidizable groups. It was found that the length of the spacer between the porphyrin and phenolic fragments does not affect the antiradical activity of the conjugate.

APA, Harvard, Vancouver, ISO, and other styles

22

Szwejda-Grzybowska, Justyna I., Ryszard Kosson, and Maria Grzegorzewska. "The Effect of Short-term Storage and the Hot Water Treatment of Fresh-Cut Pepper Fruit cv. ‛Blondy F1’ and ‛Yecla F1’ on the Content of Bioactive Compounds and Antioxidant Properties." Journal of Horticultural Research 24, no. 2 (December 1, 2016): 83–90. http://dx.doi.org/10.1515/johr-2016-0024.

Full text

Abstract:

Abstract The aim of the experiment was to determine the changes in the contents of bioactive compounds and antioxidant/antiradical activity in fresh-cut fruits of sweet pepper cv. ‘Blondy F1’ and ‘Yecla F1’, depending on the postharvest treatment. Treatment with hot water and short-term storage decreased the content of bioactive compounds and antioxidant/antiradical activity of fruit peppers. The treatment with water at 55 °C for 12 sec. of fresh-cut fruits caused lower losses in content of bioactive compounds and antioxidant/antiradical activities than the treatment with water at 45 °C for 10 min. There was a significant correlation between the content of total polyphenols and antioxidant and antiradical activity of pepper fruits depending on the cultivar and the experimental season.

APA, Harvard, Vancouver, ISO, and other styles

23

Tajalli, F. "Evaluation of Antiradical Activity Grape Seeds and Olive (Olea europaea) Pits Extracts." Journal of Scientific Research 6, no. 1 (December 30, 2013): 185–90. http://dx.doi.org/10.3329/jsr.v6i1.16654.

Full text

Abstract:

The antiradical activity of grape seeds and olive pits extracts were investigated. The aim of this study is evaluating the radical scavenging activity of methanol extracts of olive pits and grape seeds and to recover a functional and antiradical compound from olive oil and fruit juices factories waste and also for environmental treatment. The antiradical properties of ripe and unripe olive pits (RIOP and URIOP) and grape seeds (IGS) that are respectively used in Iranian oil industries and fruit juices producers are examined. All seeds and pits extracts showed DPPH radical scavenging activity ranging from 24.51 to 97.06. For this purpose a methanolic extract was prepared from each of the RIOP, URIOP and IGS and their radical scavenging ability is determined with DPPH method. For this trial the effect of 3 different dilutions (100, 200 and 300 ?g/L) of RIOP, URIOP, IGS extracts was used, separately. It was appeared that in above 100 ppm concentrations the antiradical properties reaches to its maximum activity. Also, IGS extract shows better effects in 100 ppm concentrations in comparison with RIOP, URIOP and ascorbic acid. The study shows that grape seeds can be used as a rich source of functional and antiradical compound and anticancer drugs production. Keywords: Iranian olive pits; DPPH; Antiradical activity; Radical scavenging; Grape seeds. © 2014 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v6i1.16654 J. Sci. Res. 6 (1), 185-190 (2014)

APA, Harvard, Vancouver, ISO, and other styles

24

Savel'yeva, Yelena Yevgen'yevna, Yekaterina Ziyadkhanovna Lapkina, Nadezhda Anatol'yevna Bulgakova, Yekaterina Sergeyevna Tyutrina, and Vladimir Ivanovich Kurbatskiy. "A STUDY OF THE ANTIOXIDANT ACTIVITY OF PLANTS OF THE GENUS POTENTILLA L." chemistry of plant raw material, no. 2 (June 10, 2020): 189–96. http://dx.doi.org/10.14258/jcprm.2020027261.

Full text

Abstract:

In this work, a comparative assessment of the antiradical properties of some species of the genus Potentilla L. is carried out to identify the most promising in terms of further study. The aboveground part of P. chrysantha Trevir., P. canescens Bess., P. tergemina Sojak, P. erecta (L.) Raeusch., P. paradoxa Nutt. ex Tott. et Gray, P. approximata Bunge, as well as the aboveground and underground parts of P. anserina L. were used as a research object, collected in the vicinity of Tomsk. The antiradical activity of the extracts of the studied plants was evaluated spectrophotometrically, observing the kinetics of the recovery of the stable radical of the DPPH extract. The dependence of the antiradical activity on the concentration and stability of the studied extracts was examined using P. paradoxa as an example. The total amount of phenolic compounds and flavonoids in the studied extracts was estimated. The specific absorption coefficient of gallic acid was found to be 47.3. For the aboveground parts of seven Potentilla species, the antiradical activity of extracts on ethyl alcohol 40 and 70% is significant and is in a narrow range from 77.57 to 80.91% for extracts on ethyl alcohol 40%, in a slightly wider range from 70.99 to 86.58% for extracts on ethyl alcohol 70%. A wide range of antiradical activity from 14.80% (P. tergemina) to 70.40% (P. paradoxa) is observed for 95% ethyl alcohol extracts. The difference in the chemical composition of ethanol extracts of individual representatives of the genus Potentilla significantly affects the antiradical activity with an increase in the concentration of ethyl alcohol.

APA, Harvard, Vancouver, ISO, and other styles

25

Safonov, A. A., and I. S. Nosulenko. "Antiradical activity of novel 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives." Current issues in pharmacy and medicine: science and practice 14, no. 2 (June 1, 2021): 162–66. http://dx.doi.org/10.14739/2409-2932.2021.2.230129.

Full text

Abstract:

The process of studying free radicals began in the middle of the last century (the free radical theory of aging in 1956). Multiple studies have revealed the effect of free radicals on the cells of the body and the development of various diseases, such as diabetes, autoimmune diseases, diseases of the nervous system, and others. As a result, the term antioxidant has emerged, compounds that reduce and prevent the effects of free radicals. Most of the newly synthesized substances are studied for their antiradical properties. 1,2,4-Triazole derivatives are no exception, which has already proven themselves as biologically active compounds. The aim of this work was the investigation antiradical activity among 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives. Materials and methods. Previously synthesized 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives were used as test compounds. The research of antiradical activity was based on the interaction between 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives and 2,2-diphenyl-1-picrylhydrazyl (DPPH) in vitro. DPPH is a stable free radical. The color of its alcoholic solutions were intense purple (λmax = 517 nm). When DPPH interacted with compounds that were capable of scavenging free radicals, it produced products. These products are yellow in color and do not absorb light of the aforementioned wavelength. The study was carried out according to the method. Results. The antiradical activity of 10 new 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives was studied. Most of the test compounds show antiradical activity against DPPH. Compound 1 was the most active at a concentration of 1 × 10-3 M and the antiradical effect was close to ascorbic acid. Conclusions. The most active compound is 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol, which in a concentration of 1 × 10-3 M has an antiradical effect in 88.89 %. When reducing the concentration to 1 × 10-4 M, also reduces the antiradical activity to 53.78 %. Some conclusions are drawn regarding the “structure – effect” dependence between 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol derivatives: – the introduction of 4-fluorobenzylidene radical (compound 2) into the 4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol molecule results in a slight decrease in activity; – the introduction of 2-hydroxybenzylidene radical (compound 3) into initial molecule results a high antiradical effect, which hardly changes with decreasing concentration; – transformation to 2-((5-(thiophen-2-ylmethyl)-4-((R)amino)-4H-1,2,4-triazol-3-yl)thio)acetic acid has almost no effect on antiradical activity, except for compound 9 (the antiradical effect is reduse).

APA, Harvard, Vancouver, ISO, and other styles

26

Milackova, Ivana, Lucia Kovacikova, Miroslav Veverka, Ján Gallovic, and Milan Stefek. "Screening for antiradical efficiency of 21 semi-synthetic derivatives of quercetin in a DPPH assay." Interdisciplinary Toxicology 6, no. 1 (March 1, 2013): 13–17. http://dx.doi.org/10.2478/intox-2013-0003.

Full text

Abstract:

Abstract The group of 21 novel semi-synthetic derivatives of quercetin was screened for the antiradical efficiency in a DPPH assay. The initial fast absorbance decrease of DPPH, corresponding to the transfer of the most labile H atoms, was followed by a much slower absorbance decline representing the residual antiradical activity of the antioxidant degradation products. Initial velocity of DPPH decolorization determined for the first 75-s interval was used as a marker of the antiradical activity. Application of the kinetic parameter allowed good discrimination between the polyphenolic compounds studied. The most efficient chloronaphthoquinone derivative (compound Ia) was characterized by antiradical activity higher than that of quercetin and comparable with that of trolox. Under the experimental conditions used, one molecule of Ia was found to quench 2.6±0.1 DPPH radicals.

APA, Harvard, Vancouver, ISO, and other styles

27

Sroka, Zbigniew. "Antioxidative and Antiradical Properties of Plant Phenolics." Zeitschrift für Naturforschung C 60, no. 11-12 (December 1, 2005): 833–43. http://dx.doi.org/10.1515/znc-2005-11-1204.

Full text

Abstract:

The plant phenolic compounds such as flavonoids, tannins and phenolic acids appeared to be strong antiradical and antioxidant compounds. The number of hydroxy groups and the presence of a 2,3-double bond and orthodiphenolic structure enhance antiradical and antioxidative activity of flavonoids. The glycosylation, blocking the 3-OH group in C-ring, lack of a hydroxy group or the presence of only a methoxy group in B-ring have a decreasing effect on antiradical or antioxidative activity of these compounds. Tannins show strong antioxidative properties. Some tannins in red wine or gallate esters were proved to have antioxidative effect in vivo. The number of hydroxy groups connected with the aromatic ring, in ortho or para position relative to each other, enhance antioxidative and antiradical activity of phenolic acids. The substitution of a methoxy group in ortho position to the OH in monophenols seems to favour the antioxidative activity of the former.

APA, Harvard, Vancouver, ISO, and other styles

28

Kupaeva, N. V., and E. A. Kotenkova. "Current view on the assessment of antioxidant and antiradical activities: A mini review." IOP Conference Series: Earth and Environmental Science 854, no. 1 (October 1, 2021): 012048. http://dx.doi.org/10.1088/1755-1315/854/1/012048.

Full text

Abstract:

Abstract The main problems in assessing the antioxidant properties of plant biologically active compounds are discussed in this review. Antioxidant potential should be considered as a combination of antioxidant and antiradical activities, since antiradical activity is part of the antioxidant activity and does not always coincide with antioxidant activity. The mechanisms of action and the existing experimental and computational methods for their evaluation were reviewed. Methods like FRAP, CUPRAC etc. could be used for assessment of antioxidant activity of plant compounds, but it is necessary to perform studies on cell cultures or laboratory animals in order to determine mechanisms of action on the antioxidant system of a living organism. The current methodological approaches for studying antiradical activity and its mechanisms include experimental methods such as DPPH, ABTS and ORAC, and computational methods based on density functional theory. The main thermodynamic parameters for evaluating antiradical mechanisms (HAT, SET-PT and SPLET) are the bond dissociation enthalpy, ionization potential, proton dissociation enthalpy, proton affinity, and electron transfer enthalpy, among others. The existing approaches for determining the antiradical mechanisms of antioxidants are quite informative, but can still cannot predict or determine by in vitro methods the antioxidant mechanism of these compounds in organisms consisting of many complex individual systems.

APA, Harvard, Vancouver, ISO, and other styles

29

Dimiņš, Fredijs, Velga Miķelsone, and Miķelis Kaņeps. "Antioxidant Characteristics of Latvian Herbal Tea Types." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences 67, no. 4-5 (November 1, 2013): 433–36. http://dx.doi.org/10.2478/prolas-2013-0067.

Full text

Abstract:

Abstract The aim of the study was to characterise antioxidative properties and antiradical activity of the herbal tea collection in Latvia. High-pressure liquid chromatography and spectrophotometry methods were used to characterise antioxidant properties of herbal tea. Antiradical activity was determined spectrophotometrically. The antiradical scavenging activity was measured by the DPPH (2,2-diphenyl-1-picrylhydrazyl) reaction. The herbal tea antiradical scavenging activity was estimated as the broken down quantity of DPPH on 100 grams of the herbal tea. Individual polyphenols in the herbal tea were identified and determined by liquid chromatography. Antiradical scavenging activity of the herbal tea was found to be 104 mol 100 g-1 tea. The following polyphenols were identified chromatographically in herbal tea: gallic, caffeic, chlorogenic, ferulic acids, rutin, catechin, vanillin, and epicatechin. Altogether 12 different varieties of herbal tea samples were analyzed. The results showed that different types of herbal tea substantially differed in composition. Polyphenol content of herbal teas was in the range of 1 mg in 100 g of tea up to 8 g per 100 g of tea. In the case of virus-related disease, infections and weakness of the organism, it is recommended to use tea with high content of rutin, as in Verbascum thapsiforme Schr., Alchemilla vulgaris L., Comarum palustre L. herbal tea.

APA, Harvard, Vancouver, ISO, and other styles

30

Rusina, I. F., L. A. Smurova, and T. L. Veprintsev. "Evaluation of antiradical activity of Schiff bases." Russian Chemical Bulletin 71, no. 3 (March 2022): 502–7. http://dx.doi.org/10.1007/s11172-022-3440-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Vladimirov, Yu A., É. A. Parfenov, O. M. Epanchintseva, V. S. Sharov, E. S. Dremina, and L. D. Smirnov. "Antiradical activity of copper(II) coumarin chelates." Bulletin of Experimental Biology and Medicine 113, no. 5 (May 1992): 641–44. http://dx.doi.org/10.1007/bf00783744.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Smejkal, Karel, Pavla Holubova, Ales Zima, Jan Muselik, and Margita Dvorska. "Antiradical Activity of Paulownia tomentosa (Scrophulariaceae) Extracts." Molecules 12, no. 6 (June 27, 2007): 1210–19. http://dx.doi.org/10.3390/12061210.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Tumbas, Vesna, Sonja Djilas, Jasna Čanadanović-Brunet, Gordana Ćetković, Diego A. Moreno, Jelena Vulić, and Slađana Savatović. "ANTIRADICAL AND ANTIHYPERGLYCEMIC ACTIVITY OF RASPBERRY POMACE." Reviews on Clinical Pharmacology and Drug Therapy 10, no. 2 (June 15, 2012): 109. http://dx.doi.org/10.17816/rcf102109.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Utkina, Natalia K., Natalia D. Pokhilo, and Lyubov N. Atopkina. "Antiradical Activity of Naphthazarin-Carbohydrate Nonglycoside Conjugates." Natural Product Communications 14, no. 5 (May 2019): 1934578X1984817. http://dx.doi.org/10.1177/1934578x19848170.

Full text

Abstract:

The ABTS·+ scavenging activity of known (4, 6-8) and new (5, 9-12) naphthazarin-carbohydrate nonglycoside conjugates, and methoxynaphthazarins 1-3 was evaluated. The study of structure-activity relationships showed that the presence of carbohydrate fragments in the structure of naphthazarin-carbohydrate conjugates increased their antiradical activity compared with starting methoxynaphthazarins. Antiradical activity depends on the structure of carbohydrate fragments, their number, and position. Depending on the carbohydrate fragment the activity increased in the following order: methyl-α-d-glucopyranoside < d-glucofuranose < 1,2- O-isopropylidene-α-d-glucofuranose. The 2 sugar residues and their 3,7-position enhanced the activity of the conjugates.

APA, Harvard, Vancouver, ISO, and other styles

35

Martínez, Ana, and Antonio J. Melendez-Martínez. "Lycopene, oxidative cleavage derivatives and antiradical activity." Computational and Theoretical Chemistry 1077 (February 2016): 92–98. http://dx.doi.org/10.1016/j.comptc.2015.11.001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Fedoseeva, A. A., O. S. Lebedkova, L. V. Kanibolotskaya, A. N. Shendrik, V. V. Dudzinskaya, L. N. Tkachenko, and N. V. Shineva. "Composition and antiradical activity of lilac extracts." Pharmaceutical Chemistry Journal 45, no. 2 (May 2011): 91–92. http://dx.doi.org/10.1007/s11094-011-0567-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Kerimov, R. F., and A. I. Dzhafarov. "Antiradical activity of retinal lipids during illumination." Bulletin of Experimental Biology and Medicine 110, no. 1 (July 1990): 907–10. http://dx.doi.org/10.1007/bf00839925.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Utami, Wahyu, Muhammad Da’i, Viesa Rahayu, Prihantini Kurnia Sari, Dian Werdhi Kusumanegara, and Anik Rohayati. "Aktivitas Antiradikal Berbagai Fraksi dari Ekstrak Etanol dan Ekstrak Etil Asetat Daun Eugenia uniflora L." Talenta Conference Series: Tropical Medicine (TM) 1, no. 3 (December 20, 2018): 128–33. http://dx.doi.org/10.32734/tm.v1i3.277.

Full text

Abstract:

Penelitian pendahuluan tentang aktivitas antioksidan ekstrak etanol dan ekstrak etil asetat daun dewandaru (Eugenia uniflora L.) menunjukkan potensi anti radikal bebas yang tinggi dari kedua ekstrak. Oleh karena itu telah dilakukan fraksinasi ekstrak etanol dan ekstrak etil asetat daun dewandaru, serta pengujian aktivitas antiradikal dari masing-masing fraksi. Selain itu, penelitian ini juga bertujuan untuk mengetahui apakah ada korelasi antara kandungan fenol dan flavonoid total dalam berbagai fraksi tersebut dengan aktivitas antiradikalnya. Daun dewandaru diekstraksi dengan kloroform, etil asetat, dan etanol secara maserasi bertingkat. Selanjutnya dilakukan fraksinasi terhadap masing-masing ekstrak etanol dan ekstrak etil asetat menggunakan kromatografi kolom gravitasi dengan fase diam silika G60 dan fase gerak campuran perbandingan tertentu antara kloroform, etil asetat, etanol, dan air secara gradien kepolaran. Aktivitas antiradikal diukur secara spektrofotometri dengan pereaksi DPPH (2,2-diphenyl-1-picrylhidrazyl) dan sebagai pembanding digunakan vitamin E. Penentuan kadar fenol dan flavonoid total dalam fraksi secara spektrofotometri menggunakan pereaksi Folin Ciocalteu untuk penetapan kadar fenol total, sedangkan untuk penentuan kadar flavonoid total menggunakan pereaksi AlCl3. Hasil penelitian menunjukkan bahwa fraksi-fraksi dari ekstrak etil asetat dan ekstrak etanol daun dewandaru mempunyai aktivitas antiradikal yang cukup tinggi. Lima fraksi dari ekstrak etanol memiliki aktivitas antiradikal lebih tinggi dibanding vitamin E. Aktivitas antiradikal paling tinggi ditunjukkan dengan nilai ARP (antiradical power) sebesar 3496,5 mg DPPH/mg sampel, sedangkan vitamin E sebesar 1776,20 mg DPPH/mg sampel. Korelasi antara kadar fenol maupun flavonoid total dalam berbagai fraksi tersebut dengan aktivitas antiradikalnya menunjukkan korelasi positif dengan korelasi sebesar 0,55 dan 0,45. Berdasarkan hasil diatas dapat disimpulkan bahwa fraksi-fraksi polar daun dewandaru mempunyai aktivitas antiradikal yang lebih tinggi daripada vitamin E, namun aktivitas tersebut berkorelasi rendah dengan kandungan fenol dan flavonoid totalnya. Preliminary research on the antioxidant activity of ethanol and ethyl acetate extracts of Dewandaru leaves (Eugenia uniflora L.) showed high anti-free radical potency from both extracts. Therefore fractionation of the ethanol and ethyl acetate extracts of dewandaru leaves was carried out, as well as evaluation of antiradical activity of each fraction. In addition, this study also aimed to determine whether there is a correlation between the phenol and total flavonoid content in various fractions with their anti-inflammatory activity.Dewandaru leaves were extracted by sequentially maceration with chloroform, ethyl acetate and ethanol. Furthermore, the ethanol and ethyl acetate extracts were fractionated using gravity column chromatography with silica G60 as stationary phase and increasing polarity of mobile phase by varying the ratio of chloroform, ethyl acetate and ethanol. Anti-free radical activity was determined using spectrophotometer and DPPH (2,2-diphenyl-1-picrylhidrazyl), vitamin E was used as a standard. Determination of total phenol and flavonoid content was determined using spectrophotometer, Folin Ciocalteu reagent was used to determine total phenolic content, meanwhile ALCl3 reagent was used to determine total flavonoid content. The results showed that fractions of ethanol and ethyl acetate extracts of dewandaru leaves showed high anti-free radical activity. Of all fractions, there 5 fractions of ethanol extract showed higher anti-free radical activity as compared to vitamin E. The highest anti-free radical activity is indicated by ARP (antiradical power) value of 3496.5 mg DPPH/mg sample, meanwhile the ARP value of vitamin E was 1776,20 mg DPPH/mg sample. Correlation between total phenol and flavonoid content of those fractions indicated positive correlation with correlation value of 0.55 and 0.45 respectively. Based on the results, it can be concluded that polar fractions of dewandaru leaves displayed higher anti-free radical activity as compared to vitamin E, however those activitiesdid not have correlation with their total phenolic and flavonoid content

APA, Harvard, Vancouver, ISO, and other styles

39

Da'i, Muhammad, Didiek Setiawan, and Rosita Melannisa. "Potency of Radical Scavenging Activity and Determination of Total Phenolic Content of Five Ethanolic Extract of Rhizome Zingiberaceae Family." Indonesian Journal of Cancer Chemoprevention 4, no. 1 (February 28, 2013): 457. http://dx.doi.org/10.14499/indonesianjcanchemoprev4iss1pp457-462.

Full text

Abstract:

Several studies show that some plants and fruits could protect human body from free radical danger exposure. Zingiberaceae family has some chemical substances that have antiradical activity, such as phenolic compound and flavonoid. The aim of this study is to determine the correlation of total phenolic compound towards its antiradical activity. Antiradical activity assay was determined by DPPH method (1,1 difenil-2-pikrilhidrazil). The total phenolic compound is determined by spectrofotometry using Folin-Ciocalteu reagent and counted as GAE (Gallic Acid Equivalent). Based on this study, the total phenolic concentration of ethanolic extract of jahe (Zingiber officinale (L.) Rosc), kencur (Kaemferia galanga L.), lengkuas (Languas galanga), lempuyang gajah (Zingiber littorale) and lempuyang pahit (Zingiber americana) is 73.99 mg/g; 23.848 mg/g; 37.841 mg/g; 49.725 mg/g and 40.802 mg/g respectively. The radical scavenging activity (IC50) of jahe (27.38 µg/mL), lengkuas (93,27 µg/mL), lempuyang pahit (105,08 µg/mL), meanwhile lempuyang gajah and kencur show low activity of radical scavenging.Keywords: Zingiberaceae, total phenolic compound, antiradical, DPPH

APA, Harvard, Vancouver, ISO, and other styles

40

Yamin, Yamin, Ruslin Ruslin, Sabarudin Sabarudin, Nurramadhani A. Sida, Henny Kasmawati, and La Ode Muhammad Diman. "Determination of Antiradical Activity, Total Phenolic, and Total Flavonoid Contents of Extracts and Fractions of Langsat (Lansium domesticum Coor.) Seeds." Borneo Journal of Pharmacy 3, no. 4 (November 30, 2020): 249–56. http://dx.doi.org/10.33084/bjop.v3i4.1500.

Full text

Abstract:

Lansium domesticum Coor. is a fruit species from the Meliaceae family, which is a tropical plant native to Southeast Asia. Local citizens call it langsat, longkong, or duku and have used it as traditional medicine. The seeds of L. domesticum are used as a fever medicine, its bark is used to treat scorpion sting, and its leaves are used to repel mosquitoes. Because of its various uses, it is necessary to explore the antiradical potential of L. domesticum seeds. This study aims to determine the antiradical potential of L. domesticum seeds extract and fractions by using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and to discover compounds that act as antiradical. Lansium domesticum seed powder was macerated with methanol, and then the extract was concentrated using a rotary evaporator and fractionated by n-hexane and ethyl acetate. The antiradical assay was conducted on extract and fractions by using DPPH radicals. Phenolic and flavonoid contents from extract and fractions were also tested. The ethyl acetate fraction obtained strong antiradical potential with an IC50 value of 8.938 � 0.031 �g/mL. Total phenolic and flavonoid contents of ethyl acetate fraction were higher with values ??of 58.25 � 0.501 mgGAE/g sample and 75.123 � 0.175 mgQE/g sample, respectively. Correlation of phenolic and flavonoid contents, which inhibited radicals had R2 values ??of 0.9182 and 0.7658. Ethyl acetate fraction of L. domesticum seeds had very strong antiradical activity. Further isolation is expected to be conducted to discover which compounds are the most responsible as antiradical.

APA, Harvard, Vancouver, ISO, and other styles

41

Dimiņš, Fredijs, and Ingrīda Augšpole. "Total Phenolic, Antioxidant Activities and Flavonoid Contents of Herbal Syrups." Key Engineering Materials 800 (April 2019): 60–64. http://dx.doi.org/10.4028/www.scientific.net/kem.800.60.

Full text

Abstract:

The aim of the study was to characterize antioxidative properties and antiradical activity of the herbal syrups collection in Latvia. Spectrophotometry was used to characterize antioxidant properties of herbal syrups. Antiradical activity, total phenols and content of flavonoids were determined spectrophotometrically. The antiradical scavenging activity was measured by the DPPH (2.2-diphenyl-1-picrylhydrazyl) reaction. The herbal syrups antiradical scavenging activity was estimated by the amount of DPPH of reagent using in reaction with a sample of vegetable syrup (in percent) and by Trolox equivalent. The total phenolic compounds were determined by using the Folin – Ciocalteu method. The total phenolic content was expressed in mg of the gallic acid equivalents. The content of flavonoids was determined by using reaction between the AlCl3 and flavonoids. Antiradical scavenging activity by Trolox equivalent of the herbal syrups was found from 81 to be 130 mg 100 g-1 herbal syrups. The content of total phenols was found from 22 to be 282 mg GAE 100 g-1, but content of total flavonoids by quercetin equivalent was found from 1 to 44 mg QE 100 g-1. In case of increased disease problems, syrups with increased antioxidant content should be used. However, the specificity of each disease should be taken into account as well as the content of certain compounds in the plants.

APA, Harvard, Vancouver, ISO, and other styles

42

Volkov, V. A., M. V. Voronkov, N. N. Sazhina, D. V. Kurilov, D. V. Vokhmyanina, O. V. Yamskova, Yu Ts Martirosyan, D. L. Atroshenko, L. Yu Martirosyan, and V. S. Romanova. "Mechanism of the Antioxidant Activity and Structure–Activity Relationship of N-Monosubstituted Amino Acid Derivatives of Fullerene С60." Kinetics and Catalysis 62, no. 3 (May 2021): 395–403. http://dx.doi.org/10.1134/s0023158421030095.

Full text

Abstract:

Abstract The kinetic characteristics, mechanisms of activity, and relationship between the antioxidant activity and the molecular and supramolecular structure of fullerene C60 and some of its N-monosubstituted amino acid derivatives have been studied. The introduction of an amino acid substituent in the C60 fullerene molecule led to an increase in its antiradical activity in the free radical oxidation of a water-soluble target (fluorescein). The mechanism of the antioxidant activity of amino acid derivatives of fullerene is not associated with the hydrogen atom transfer, electron donation, or catalysis of peroxide decomposition. It was demonstrated that the structure of the amino acid substituent does not affect the antiradical properties, which are thus determined only by the effective total surface area of the nanoparticles of the fullerene C60 derivatives and increase when their size decreases. This surface can be characterized as nanowalls on which the radical death occurs. A change in the concentration of the compounds in solution does not lead to a change in the relative antiradical activity and hence in the nanoparticle size. The results of this study are important for understanding the biological activity of this group of compounds.

APA, Harvard, Vancouver, ISO, and other styles

43

Benyagoub, Elhassan, Nouria Nabbou, Miaad K. Alkhudhairy, and Amal Dine. "IN VITRO EVALUATION OF THE ANTIOXIDANT PROPERTY AND DPPH RADICAL SCAVENGING KINETIC BEHAVIOR OF ALGERIAN QUERCUS ROBUR L. LEAVES’ SELECTIVE EXTRACTS." Indian Drugs 59, no. 11 (November 25, 2022): 37–45. http://dx.doi.org/10.53879/id.59.11.13218.

Full text

Abstract:

Today, there is a growing demand for natural antioxidants. The unbalanced production and consumption of reactive oxygen species cause many disorders such as cancer, arteriosclerosis, Alzheimer’s disease and aging. For this purpose, the present study was a part of the in vitro evaluation of the antioxidant activity of Quercus robur L. leaves’ selective extracts, namely tannins and saponins groups. The antioxidant activity was evaluated by using two techniques: the DPPH radical scavenging activity method and the ferric reducing antioxidant power method. In addition, a kinetic behavior study of the antiradical activity was established. The obtained results show that tannins and saponins extracts have a significant free radical scavenging activity with IC50 values of 0.128 and 0.145 mg mL-1, respectively. Moreover, the kinetic behavior of the scavenging ability of the studied extracts makes it possible to determine the antiradical efficiency, the antiradical power, the percentage of the remaining DPPH free radical, the TIC50 parameter, the half-reaction time and the equilibrium antiradical reaction time. These results showed that the tested extracts provided a significant antioxidant activity. This plant can keep an important value in pharmacy and herbal medicine, and act as natural agents in food applications.

APA, Harvard, Vancouver, ISO, and other styles

44

Andrushchenko, Olena, Olena Vergun, and Dzhamal Rakhmetov. "Antioxidant capacity of Cosmos sulphureus plants grown in the temperate climate." Plant Introduction 93-94 (April 28, 2022): 37–45. http://dx.doi.org/10.46341/pi2021021.

Full text

Abstract:

Cosmos sulphureus is an adventitious species for Europe and Ukraine in particular. It originates from Central and South America, where it grows in tropical and subtropical climates. The climatic conditions of Kyiv are characterized as temperate, with an absolute temperature minimum of –32.2 °C, an absolute maximum of +39.9 °C, and average annual rainfall of 649 mm.Plants were analyzed in the flowering phase, divided into inflorescences, leaves, stems, and roots, dried at +35 °C and then extracted with methanol and water. The determination of the antiradical activity was carried out according to a modified method using a DPPH (2,2-diphenyl-1-picrylhydrazyl) radical inhibition reaction. The highest antiradical activity was detected in inflorescences (59.60–81.81 % inhibition) and leaves (79.81–89.12 % inhibition). Stem extracts had an average level of inhibition (19.63–65.93 %), and root extracts showed only 2.54–39.46 % inhibition. Correlation analysis showed a strong relationship between leaves and stems (r = 0.84), leaves and roots (r = 0.81), and stems and roots (r = 0.91).Extracts of C. sulphureus plants grown in temperate climate were found having a high antioxidant potential but lower than that reported for tropical and subtropical regions. It was found that higher intensity of coloration of marginal florets of the capitulum does not correlate with a higher antiradical activity. Methanolic and water extracts of inflorescences of the genotype CSCO-368812 with intensilly colored perianth inhibited only 59.60 % and 71.50 % of radicals, while similar extracts of the genotype CS-361294 with lighter florets inhibited 71.17 % and 81.81 % of radicals, respectively. Instead, there was a difference in antiradical activity depending on applied extractant. Methanolic extracts of vegetative organs (leaves, stems, roots) prevail over water extracts in terms of their antiradical activity. However, water extracts of inflorescences of both genotypes demonstrated higher level of antiradical activity.

APA, Harvard, Vancouver, ISO, and other styles

45

Fatrcová-Šramková, Katarína, Ján Brindza, Eva Ivanišová, Tünde Juríková, Marianna Schwarzová, Vladimíra Horčinová Sedláčková, and Olga Grygorieva. "Morphological and antiradical characteristics of Rugosa rose (Rosa rugosa Thunb.) fruits canned in different kind of honeys and in beverages prepared from honey." Potravinarstvo Slovak Journal of Food Sciences 13, no. 1 (June 28, 2019): 497–506. http://dx.doi.org/10.5219/1065.

Full text

Abstract:

The aim of the work was to determined the basic morphological and morphometric traits of rugosa rose (Rosa rugosa Thunb.) and antiradical activity of fruit pulp canned in different kind of honeys and in beverages prepared from honey. In experiments there were used 4 genotypes of roses originated from arboretum Mlyňany (Slovakia). The evaluation of 11 morphometric traits of fruit showed that the average weight of the fresh fruit without pedicle reached up 5.14 – 5.46 g, the weight of pedicle was 0.05 – 0.08 g, weight of pulp and seeds 4.80 – 5.13 g, weight of calyx 0.25 – 0.31 g, length and width of fruit (16.10 – 18.13 mm, 21.38 – 22.46 mm), the number of seeds in fruit 48.45 – 71.05, thickness of pulp 2.63 – 2.97 mm. Separated fruit pulp was canned at 40 °C and 80 °C and premixed in robinia honey and honeydew honey. Beverages were prepared by mixture of fruit pulp in honey (15 g) with cold water (150 mL). Antiradical activity was determined by DPPH method in fruit pulp (in methyl alcohol and water extracts), in honeys (black locust honey and honeydew honey) and beverages. There had been confirmed statistically significant differences in morphological traits, especially in colour and shape of fruit. Antiradical activity of fresh fruit pulp in methyl alcohol extract was determined 94.59%, in water extract 89.71%. Antiradical activity of black locust honey was 7.63%, honeydew honey 6.54%. Antiradical activity was determined also adding honeydew honey and black locust honey to fresh pulp of fruit prepared at 80 °C (33.55% and 77.58%). In beverages prepared from fresh pulp, honey and water it was investigated the higher values of antiradical activity in samples with addition of honeydew honey (81.81 – 83.86%) in comparison with robinia honey (75.57 – 79.96%).

APA, Harvard, Vancouver, ISO, and other styles

46

ZANTE, Abdoul Aziz, Martin Bienvenu SOMDA, Lassina OUATTARA, Daouda ZOUNGO, F. Daniel PODA, R. Justin OUEDRAOGO, Yacouba SANOU, B. Pawendé KABRE, K. Abdourasmane KONATE, and Georges Anicet OUEDRAOGO. "Antiradical and inhibitory activities of hydroethanolic extracts of Phyllanthus amarus and Striga hermonthica on α-amylase." Journal of Drug Delivery and Therapeutics 12, no. 3-S (June 15, 2022): 150–53. http://dx.doi.org/10.22270/jddt.v12i3-s.5517.

Full text

Abstract:

Objective: The aim of this study was to evaluate the antiradical and inhibitory activity of whole plant extracts of Phyllanthus amarus and Striga hermonthica on α-amylase. Methods: The crude 70% (v/v) hydroethanolic extracts obtained were used for the assay of polyphenols, the antiradical test with DPPH, the test for the inhibition of α-amylase with DNS (3,5-dinitrosalicylic). The enzyme extracts were obtained from sorghum malt (Sorghum bicolor). Results: It appears from this study that the extract of P. amarus was richer in polyphenols than the extract of S. hermonthica. Regarding the antiradical activity, the extract of S. hermonthica showed an IC50 of 339.06 ± 1.43 µg/mL against 77.74 ±2.73 µg/mL for the extract of P. amarus. Regarding the anti α-amylase activity, the extract of P. amarus inhibited IMS127 and KMTC 274 respectively 43.64 ±0.59% and 66.28 ±1.97%. On the other hand, the extract of S. hermonthica presented an inhibition of 3.93 ±0.91% on IMS127 and 14.85 ±1.62% on KMTC 274. The extract of P. amarus presents a good antiradical activity and anti α-amylase compared to S. hermonthica extract. In conclusion, these results partly explain the use of these plants in traditional medicine to treat or relieve people suffering from diabetes. Keywords : α-amylase, inhibition, polyphenols, antiradical, diabetes

APA, Harvard, Vancouver, ISO, and other styles

47

Budikafa, MJ, Rumiyati, S. Riyanto, and A. Rohman. "2,2’-Diphenyl-1-picrylhydrazyl and 2,2′-azinobis-(3-ethyl-benzothiazoline-6-sulfonic acid) scavenging assay of Extract and Fractions of Rambutan (Nephelium Lappaceum L.) Seed." Dhaka University Journal of Pharmaceutical Sciences 18, no. 2 (September 22, 2019): 145–52. http://dx.doi.org/10.3329/dujps.v18i2.43256.

Full text

Abstract:

This research was intended to evaluate the antiradical activity of extracts and fractions of rambutan seed using 2,2’- diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+). The powder of rambutan seed was subjected to maceration with methanol. The methanolic extract obtained was then fractionated using petroleum ether (PE), dichloromethane (DCM) and ethyl acetate (EA) to obtain PE, DCM and EA fractions, respectively. The methanol extract and fractions were then assayed for antiradical activities and phenolics and flavonoid contents.The results showed that EA fraction has lowest IC50 values among extract and fractions evaluated, i.e. 244.6 ± 2.1 μg/ml using DPPH radical. Using ABTS radical, EA fraction (0.1%) also revealed the highest antiradical activity of 643.4 ± 34.9 μM trolox equivalent. However, these antiradical activities were lower than those in positive controls used (vitamin C and vitamin E). The antiradical activities of extract and fractions correlated with total phenolics and flavonoid contents. The seed of rambutan fruit could be exploited as natural antioxidants to be used in food supplements. Dhaka Univ. J. Pharm. Sci. 18(2): 145-152, 2019 (December)

APA, Harvard, Vancouver, ISO, and other styles

48

Sukhomlinov, Yuri A., and Ksenia R. Bubenchikova. "Study of the antioxidant activity of the tuberous pea herb (Lathyrus tuberosus L.)." Человек и его здоровье 25, no. 3 (2022): 93–98. http://dx.doi.org/10.21626/vestnik/2022-3/10.

Full text

Abstract:

Objective: to study the antioxidant and antiradical activity of extracts from the tuberous pea herb. Materials and methods. The study object was tuberous pea herb collected in Kursk region in 2020-2021 during the flowering period of plants. The antioxidant and antiradical activities of aqueous and aqueous-alcoholic extracts from the herb of tuberous pea were investigated. Antioxidant activity was evaluated by titrimetric method based on the interaction of potassium permanganate and reducing substances contained in the extract from raw materials of tuberous pea herb. The antiradical activity was studied by spectrophotometric method according to the ability of extracts to inactivate 1,1-diphenyl-2-picrylhydrazyl. The content of phenolic compounds (direct spectrophotometry) in terms of chlorogenic acid and flavonoids (differential spectrophotometry) in terms of rutin was determined. The obtained data were processed by statistical analysis. Results. By the example of the use of different extractants: water and alcohol of different concentrations, we investigated their influence on the antioxidant and antiradical activity of tuberous pea herb. The analysis of the experimental data obtained showed that all the extracts studied have antioxidant and antiradical activity, with the maximum activity found in extracts obtained from the herb using 50% and 70% ethyl alcohol as an extractant. The maximum content of phenolic compounds and flavonoids was also found in the mentioned extracts, which indicates a correlation between the antioxidant activity and the content of phenolic compounds. Conclusion. The results of the conducted experimental study allow us to conclude that the tuberous pea herb harvested in the flowering phase can be considered as a promising medicinal plant raw material of antioxidant orientation.

APA, Harvard, Vancouver, ISO, and other styles

49

WANG, HUIYUAN, CHONG WANG, CHUNBAO LI, XINGLIAN XU, and GUANGHONG ZHOU. "Effects of Phenolic Acid Marinades on the Formation of Polycyclic Aromatic Hydrocarbons in Charcoal-Grilled Chicken Wings." Journal of Food Protection 82, no. 4 (March 26, 2019): 684–90. http://dx.doi.org/10.4315/0362-028x.jfp-18-420.

Full text

Abstract:

ABSTRACT Polycyclic aromatic hydrocarbons (PAHs) are generated in meat during cooking, and pretreatment of meat is becoming increasingly popular. In this study, we aimed to elucidate the influence of different concentrations of three phenolic acid marinades and grilling temperature on the formation and inhibition of PAHs in charcoal-grilled chicken wings by using ultraperformance liquid chromatography–fluorescence detection and analysis of the antiradical activity of marinades by the DPPH (1,1-diphenyl-2-picryl-hydrazyl) method. The results showed that protocatechuic acid marinade exhibited the highest inhibitory effects, followed by gallic acid and ferulic acid marinade. Additionally, the inhibitory effects grew as the concentration of phenolic marinade increased within limits, and a plateau was eventually reached at a high concentration. Notably, we also found that PAH formation was more affected by marinating than by changing the grilling temperature. In addition, gallic acid had the strongest antiradical activity, whereas protocatechuic acid showed strong activity, and ferulic acid exhibited relativity low activity. The relationship between the antiradical activity and PAH inhibitory effects of phenolic acids suggested that the mechanism for the formation of PAHs was more complex and involved more than antiradical activity. Further studies are needed to test more types and contents of phenolic acid for inhibition of PAH formation. HIGHLIGHTS

APA, Harvard, Vancouver, ISO, and other styles

50

Vo, Quan V., and Nguyen Thi Hoa. "The radical scavenging activity of moracins: theoretical insights." RSC Advances 10, no. 60 (2020): 36843–48. http://dx.doi.org/10.1039/d0ra06555b.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Antiradical activity'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles