Academic literature on the topic 'Antiretroviral Drug Management'

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Journal articles on the topic "Antiretroviral Drug Management"

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Correia, Katharine, and Paige L. Williams. "A hierarchical modeling approach for assessing the safety of exposure to complex antiretroviral drug regimens during pregnancy." Statistical Methods in Medical Research 28, no. 2 (2017): 599–612. http://dx.doi.org/10.1177/0962280217732597.

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Combination antiretroviral regimens have achieved tremendous success in reducing perinatal HIV transmission, and have become standard of care in pregnant women with HIV. However, the large variety of combination antiretroviral regimens utilized in practice raises the question of whether some of these highly potent drugs pose other risks to the pregnancy or infant. While HIV-infected pregnant women are almost always exposed to multiple antiretrovirals concurrently, standard safety screening strategies typically consider each individual antiretroviral separately, which fails to account for poten
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Feeney, Eoin, Eavan Muldoon, and William G. Powderly. "Management of antiretroviral drug toxicity." Current Opinion in HIV and AIDS 1, no. 5 (2006): 430–36. http://dx.doi.org/10.1097/01.coh.0000239856.45485.db.

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Estes, Kristina E., Kristin H. Busse, and Scott R. Penzak. "Pharmacogenetic Considerations in the Management of HIV Infection." Journal of Pharmacy Practice 20, no. 3 (2007): 234–45. http://dx.doi.org/10.1177/0897190007304819.

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Potent combination antiretroviral drug therapy has now been available to HIV-infected patients for more than a decade, resulting in a significant decline in disease-related morbidity and mortality. Nonetheless, a number of HIV-infected individuals fail to experience the full benefit of their antiretroviral medications; some lack a robust virologic response, while others experience treatment-limiting toxicities. A number of factors may contribute to variable drug response in patients with HIV infection. Virologic, immunologic, pharmacologic, and pharmacokinetic differences between HIV-infected
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Goodlet, Kellie J., Monika T. Zmarlicka, and Alyssa M. Peckham. "Drug–drug interactions and clinical considerations with co-administration of antiretrovirals and psychotropic drugs." CNS Spectrums 24, no. 03 (2018): 287–312. http://dx.doi.org/10.1017/s109285291800113x.

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Psychotropic medications are frequently co-prescribed with antiretroviral therapy (ART), owing to a high prevalence of psychiatric illness within the population living with HIV, as well as a 7-fold increased risk of HIV infection among patients with psychiatric illness. While ART has been notoriously associated with a multitude of pharmacokinetic drug interactions involving the cytochrome P450 enzyme system, the magnitude and clinical impact of these interactions with psychotropics may range from negligible effects on plasma concentrations to life-threatening torsades de pointes or respiratory
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Yu, Zaikuan J., Eric P. Mosher, and Namandjé N. Bumpus. "Pharmacogenomics of Antiretroviral Drug Metabolism and Transport." Annual Review of Pharmacology and Toxicology 61, no. 1 (2021): 565–85. http://dx.doi.org/10.1146/annurev-pharmtox-021320-111248.

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Antiretroviral therapy has markedly reduced morbidity and mortality for persons living with human immunodeficiency virus (HIV). Individual tailoring of antiretroviral regimens has the potential to further improve the long-term management of HIV through the mitigation of treatment failure and drug-induced toxicities. While the mechanisms underlying anti-HIV drug adverse outcomes are multifactorial, the application of drug-specific pharmacogenomic knowledge is required in order to move toward the personalization of HIV therapy. Thus, detailed understanding of the metabolism and transport of anti
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Mudogo, Collins, Angeline Mulwa, and Dorothy Kyalo. "Antiretroviral Drug Management Tool and Performance of HIV/AIDS projects in Kisumu County, Kenya: A Digital Heath Solution Approach." European Journal of Theoretical and Applied Sciences 1, no. 4 (2023): 608–17. http://dx.doi.org/10.59324/ejtas.2023.1(4).56.

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The aim of this study was to assess the influence of utilization of the digital health intervention for antiretroviral drug management on performance of HIV/AIDS projects in Kisumu County. An ex-post facto cross-sectional descriptive study was conducted to gain understanding on the influence of the use of the digital health intervention for antiretroviral drug management on the performance of the HIV/AIDS projects. The study was conducted in eight (2 level V and 6 level IV) health facilities providing HIV/AIDS care and treatment in Kisumu. Using a census approach the study recruited 191 partic
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Collins, Mudogo, Mulwa Angeline, and Kyalo Dorothy. "Antiretroviral Drug Management Tool and Performance of HIV/AIDS projects in Kisumu County, Kenya: A Digital Heath Solution Approach." European Journal of Theoretical and Applied Sciences 1, no. 4 (2023): 608–17. https://doi.org/10.59324/ejtas.2023.1(4).56.

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The aim of this study was to assess the influence of utilization of the digital health intervention for antiretroviral drug management on performance of HIV/AIDS projects in Kisumu County. An ex-post facto cross-sectional descriptive study was conducted to gain understanding on the influence of the use of the digital health intervention for antiretroviral drug management on the performance of the HIV/AIDS projects. The study was conducted in eight (2 level V and 6 level IV) health facilities providing HIV/AIDS care and treatment in Kisumu. Using a census approach the study recruited 191 partic
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Deepika, B., and G. Ramya Balaprabha. "Review on Antiretroviral Considerations in HIV-Infected Patients Undergoing Bariatric Surgery." International Journal of Health Sciences and Research 13, no. 9 (2023): 150–56. http://dx.doi.org/10.52403/ijhsr.20230922.

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Bariatric surgery is a widely accepted method for promoting weight loss in individuals with obesity, including those who are living with HIV. However, there are specific challenges and factors to consider when it comes to managing antiretroviral therapy (ART) for HIV-infected patients undergoing bariatric surgery. This comprehensive review aims to provide a detailed overview of the current evidence and recommendations regarding the use of antiretroviral drugs in this population. Obesity is prevalent among people living with HIV, and bariatric surgery has proven to be an effective approach for
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Laessig, Katherine A., Jeffrey S. Murray, and Gary Chikami. "The Role of Resistance Testing in Clinical Trial Design and Product Labelling: A Regulatory Perspective." Antiviral Therapy 5, no. 1 (2000): 77–83. http://dx.doi.org/10.1177/135965350000500104.

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Assays that attempt to characterize HIV susceptibility or resistance are among the latest technologies that are likely to impact HIV clinical trial design, antiretroviral drug development and patient management. However, at present the Food and Drug Administration (FDA) have yet to approve any phenotypic or genotypic HIV resistance assay and the role of resistance testing in clinical management of patients and in drug development is ill defined. In November 1999, the Division of Antiviral Drug Products at the FDA convened a meeting of its advisory committee to consider the available informatio
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Kaska, Omolayomi Ikeoluwa. "Analysis of Drug Pricing Trends of Antiretroviral Therapies in the Management HIV/AIDS." International Journal of Research Publication and Reviews 6, no. 4 (2025): 11076–93. https://doi.org/10.55248/gengpi.6.0425.15116.

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Dissertations / Theses on the topic "Antiretroviral Drug Management"

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Mokheseng, Mamolise. "The management of antiretroviral drug distribution in the Qwaqwa District." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1016077.

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The supply of Antiretrovirals (ARVs) to HIV/AIDS patients in most of the provinces in South Africa is hindered by various factors such as ineffective and inefficient drug procurement, and drug distribution systems. In the QwaQwa district in the Free State Province, a major barrier to the consistent supply of Highly Active Antiretroviral Treatment was identified to be the lack of an effective and efficient ARV drug distribution system. This resulted in major drug supply shortages in the QwaQwa district. A continuous, uninterrupted supply of ARVs to HIV/AIDS patients is critical to avoid drug re
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Charbe, N. B. "THERAPEUTIC DRUG MANAGEMENT OF HIV-INFECTED PATIENTS WITH COMORBIDITIES." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/354114.

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Today, antiretroviral therapy is potent, convenient and usually well tolerated, capable of reducing human immunodeficiency virus (HIV) blood concentration to undetectable values within a few weeks from treatment initiation and of inducing a robust and sustained CD4 T-cell gain. Despite these unquestioned successes, the problem is far from being solved: even in countries with full access to ntiretroviral treatment, life expectancy of people under ARV therapy remains lower with respect to that of uninfected people. Furthermore, large populations of HIV infected individuals who are not diagnosed
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Scholtz, Daniël Jacobus. "Prescribing patterns of antiretroviral drugs in the private health care sector in South Africa : a drug utilisation review / Daniël Jacobus Scholtz." Thesis, North-West University, 2005. http://hdl.handle.net/10394/1723.

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Mocke, Martlie. "Medicine prescribing patterns in HIV/AIDS and non HIV/AIDS children : a comparative study in the private health care sector of South Africa / Mocke, M." Thesis, North-West University, 2010. http://hdl.handle.net/10394/7033.

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Background: According to the United Nations AIDS Reference Group (2010) and World Health Organization (2010:2), approximately 33 million people in the world had HIV/AIDS in 2009 of which 2.6 million were children. More than 30 million of these individuals resided in low– and middle–income countries. South–Africa had the highest prevalence of HIV/AIDS in the world with an estimated 5.2 million patients in 2009 (Statistics South Africa, 2010:2). Although the prevalence of human immunodeficiency virus (HIV) infection among children is reported to be high, little is known about other medication ad
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Ratau-Dintwe, Mmabatho N. P. "Management of dyslipidemia in HIV infected patients on combined antiretroviral therapy : effects of intervention." Diss., 2015. http://hdl.handle.net/2263/46146.

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Background: Clinical management of dyslipidemia is challenging, particularly hypertriglyceridemia in patients with HIV-infection. Changing combined anti-retroviral therapy (CART) and the use of lipid-lowering drugs have proven useful in treating dyslipidemia in HIV infected patients Objective: To assess the efficacy of lipid lowering drugs (LLDs) and/or CART switching, in the management of HIV-associated dyslipidemia Design: A retrospective, longitudinal cohort study Setting: Phidisa HIV research project, 6 sites in South Africa, period April 2008 and April 2011 Patients: HIV positive Sout
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Armitage, Gerry R., Ian J. Hodgson, J. Wright, K. Bailey, and E. Mkhwana. "Exploring the delivery of antiretroviral therapy for symptomatic HIV in Swaziland: threats to the successful treatment and safety of outpatients attending regional and district clinics." 2011. http://hdl.handle.net/10454/6787.

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AIM: To examine the safety and acceptability of providing antiretroviral therapy (ART) in a resource poor setting. DESIGN: Two-stage observational and qualitative study. SETTING: Rural hospital in Southern Africa. METHODS: Structured observation using failure modes and effects analysis (FMEA) of the drug supply, dispensing, prescribing and administration processes. The findings from the FMEA were explored further in qualitative interviews with eight health professionals involved in the delivery of ART. To obtain a patient perspective, a stratified sample of 14 patients receiving ART was also i
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Mahoro, Alice. "Examining the inventory management of antiretroviral drugs at community health centres in the cape metropole, Western Cape." 2013. http://hdl.handle.net/11394/3615.

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Magister Pharmaceuticae - MPharm<br>South Africa is faced with a high number of people living with HIV/AIDS, and subsequently a great need to access quality medicines for improving patient therapeutic outcomes. Antiretroviral drugs (ARVs) require rigid, efficient and effective management, due to their valuable efficacy in prolonging the survival of HIV/AIDS patients, and the limited possibility of substitution. Managing their flow is vital to ensure an uninterrupted supply. Problematic inventory management was experienced by some healthcare facilities in South Africa where in recent years it
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Netangaheni, Thinavhuyo Robert. "A hidden cohort: HIV and AIDS amongst the farming community." Thesis, 2008. http://hdl.handle.net/10500/706.

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Purpose This research project was an attempt to determine situational aspects of HIV and AIDS among the designated farming communities in the Vhembe and Mopani districts of Limpopo Province. Questions arising from the pilot project were premised on the capacity of farmers in these areas to adequately address the daunting reality and prevalence of HIV and AIDS in their communities. Research Design and Methodology The research was designed to facilitate the integration of both qualitative and quantitative approaches. A sample of 228 respondents was involved in a triangulated participatory a
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Books on the topic "Antiretroviral Drug Management"

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Ernesto, Jaramillo, Stop TB Initiative (World Health Organization), Great Britain. Dept. for International Development., and United States. Agency for International Development., eds. Guidelines for the programmatic management of drug-resistant tuberculosis: [emergency update 2008]. World Health Organization, Stop TB Department, 2008.

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Ernesto, Jaramillo, Stop TB Initiative (World Health Organization), Great Britain. Dept. for International Development., and United States. Agency for International Development., eds. Guidelines for the programmatic management of drug-resistant tuberculosis: [emergency update 2008]. World Health Organization, Stop TB Department, 2008.

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P, Flaherty John, ed. Contemporary diagnosis and management of HIV/AIDS infections. 2nd ed. Handbooks in Health Care, 2003.

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World Health Organization (WHO). Management of MDR-TB: A field guide, a companion document to Guidelines for the programmatic management of drug-resistant tuberculosis. World Health Organization, 2009.

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Bartlett, John G. Medical management of HIV infection. 2nd ed. Johns Hopkins Medicine, Health Publishing Business Group, 2005.

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Bartlett, John G. Medical management of HIV infection. Physicians & Scientists Pub., 1996.

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Bartlett, John G. Medical management of HIV infection. 2nd ed. Johns Hopkins Medicine, Health Publishing Business Group, 2005.

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Bartlett, John G. Medical management of HIV infection. TheraSim, 2008.

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Sukhābhipālʼ, Cambodia Krasuaṅ, ред. ʻEkasār sikkhakām saṃrâp vagg paṇtuaḥ paṇtāl stībī kārgrápgraṅ ūsath niṅ parikkhār saṃrâp qnakgrápgraṅ ūsathsthān mandīr bedy paṅqaek / sevāthaedaṃ-byāpāl jaṃnȳ ūkas niyam niṅ byāpāl ṭoy ūsath prachaṃṅ merog qeṭs̊: Training curriculum on drugs and logistic management for logistic officer at referral hospital, opportunistic infection & antiretroviral service. Krasuaṅ Sukhābhipāl, 2006.

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A Practical Guide to HIV Drug Resistance and Its Implications for Antiretroviral Treatment Strategies (HIV Clinical Management Series). International Medical Press, 2000.

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Book chapters on the topic "Antiretroviral Drug Management"

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Haire, Bridget. "Providing Universal Access While Avoiding Antiretroviral Resistance: Ethical Tensions in HIV Treatment." In Ethics and Drug Resistance: Collective Responsibility for Global Public Health. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-27874-8_3.

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Abstract The provision of effective antiretroviral therapy is an ethical imperative, and global access to antiretroviral drugs is an important aspect of this. The other less recognised aspect of effective HIV management is in ensuring that HIV does not become resistant to the drugs used in treatment (and increasingly also in prevention), as multi-drug resistant HIV poses a major threat to the sustainability of current responses to HIV control. In resource-constrained environments, the rapid scale up of access to life-saving anti-HIV treatment was achieved using a public health approach that st
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Chu, Carolyn, Lealah Pollock, and Robert Shafer. "Antiretroviral Resistance." In Fundamentals of HIV Medicine 2021. Oxford University PressNew York, 2021. http://dx.doi.org/10.1093/med/9780197576595.003.0027.

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Abstract This chapter outlines various mechanisms of HIV drug resistance as well as HIV drug resistance testing assays and clinical considerations. Transmitted HIV drug resistance and acquired HIV drug resistance are discussed in detail. Unique considerations regarding evaluation of HIV drug resistance and management for select clinical scenarios are reviewed. These scenarios include switches or simplification of the antiretroviral regimen, pregnancy, recent use of preexposure prophylaxis, “rapid” antiretroviral therapy, and care of persons with HIV in low- and middle-income countries.
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Bartlett, John G., Robert R. Redfield, and Paul A. Pham. "Antiretroviral Therapy." In Bartlett's Medical Management of HIV Infection. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190924775.003.0004.

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Abstract: This chapter is about antiretroviral therapy (ART). It includes the goals of antiretroviral therapy (according to the 2018 Department of Health and Human Services [DHHH] guidelines), and it covers recommendations for antiretroviral therapy, special co-factor considerations, and what antiretroviral regimen to start. The chapter includes a detailed discussion on the selection of the initial third ART drug, individualized selection of the initial regimen, initiating ART in a patient with HIV-associated complications, treatment of HIV-2 infection, factors that influence the probability o
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Sherman, Elizabeth M., and Taylor K. Gill. "Understanding and Managing Antineoplastic and Antiretroviral Therapy." In Fundamentals of HIV Medicine 2023. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197679098.003.0025.

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Abstract The disease states of HIV and cancer are constantly evolving. New therapies are introduced, and literature published advancing each area. The use of combination antiretroviral therapy in people with HIV and malignancies is associated with improved HIV- and cancer-related outcomes. Combining antiretroviral therapy (ART) and antineoplastic therapy is often complicated by significant drug–drug interactions, drug–disease state monitoring interactions, and overlapping toxicities. Definitive studies including both antineoplastics and antiretrovirals are uncommon, and clinical judgment must
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"HIV: management." In Oxford Handbook of Genitourinary Medicine, HIV, and Sexual Health, edited by Laura Mitchell, Bridie Howe, D. Ashley Price, Babiker Elawad, and K. Nathan Sankar. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198783497.003.0055.

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The treatment of HIV has changed radically over the past 30 years. HIV has changed from an inevitably fatal infection, to an easily treated infection and normal life expectancy if diagnosis is made early, prior to becoming immune compromised and subsequent complications. As people with HIV are living longer, and HIV clinic populations are ageing, co-morbidities, polypharmacy, and drug interactions are becoming more of a challenge. This chapter describes how and when to start antiretroviral therapy (ART), which regimen to choose, drug side effects and complications, drug resistance, and drug in
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Wyatt, Christina M. "Kidney Disease in HIV Infection and Treatment." In Kidney Protection, edited by Vijay Lapsia, Bernard G. Jaar, and A. Ahsan Ejaz. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190611620.003.0037.

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HIV-positive individuals are at increased risk of kidney disease as a result of HIV-related kidney disease, toxicity of antiretroviral therapy, and accelerated progression of comorbid kidney disease. Because of the broad spectrum of disease, kidney biopsy should be considered in all HIV-positive individuals who present with kidney disease. While an effective combination antiretroviral therapy has substantially reduced the incidence of HIV-associated nephropathy, antiretroviral therapy appears to have less impact on immune-complex kidney disease and comorbid kidney diseases. The management of k
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Garg, Ashok. "Antiretroviral Drug Therapy of Ocular Infections in AIDS." In Clinical Diagnosis and Management of AIDS (HIV) in Eye. Jaypee Brothers Medical Publishers (P) Ltd., 2006. http://dx.doi.org/10.5005/jp/books/10123_7.

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DeArmond, Patrick D., and Dustin R. Bunch. "Therapeutic drug monitoring of antiretroviral drugs for the management of human immunodeficiency infection." In Therapeutic Drug Monitoring. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-18649-3.00013-6.

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Schafer, Jason J., Elizabeth M. Sherman, and Taylor K. Gill. "Understanding and Managing Antineoplastic and Antiretroviral Therapy." In Fundamentals of HIV Medicine 2021. Oxford University PressNew York, 2021. http://dx.doi.org/10.1093/med/9780197576595.003.0032.

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Abstract This chapter reviews concepts regarding the safe and effective use of antineoplastic and antiretroviral therapy in people living with HIV and cancer. Drug interactions and medication toxicities are discussed as well as drug–disease interactions. The chapter concludes with an overview of strategies for clinical management of people with cancer and HIV.
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Rakhmanina, Natella Y., and Charles J. L. la Porte. "Therapeutic Drug Monitoring of Antiretroviral Drugs in the Management of Human Immunodeficiency Virus Infection." In Therapeutic Drug Monitoring. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-385467-4.00017-8.

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Conference papers on the topic "Antiretroviral Drug Management"

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Kafer, Maria Eduarda Paludo, Beatriz Calsolari Ranha, Isadora Vidal de Carvalho, et al. "HIV in pediatrics - Early diagnosis and infectious management." In V Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvmulti2024-168.

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Introduction: Human immunodeficiency virus (HIV) infection in pediatrics represents a significant challenge for global health, as children can acquire the virus vertically during pregnancy, childbirth or breastfeeding. Children's vulnerability to HIV is accentuated by the risks associated with the mother-child bond. This study is based on a literature review, highlighting research that addresses the challenges and treatment strategies of the disease. Objective: The main objective of this study is to examine the approach to HIV in children, exploring research that discusses therapeutic strategi
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