Relevant bibliographies by topics / Antisense Plasmids Nucleic acid hybridization

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Academic literature on the topic 'Antisense Plasmids Nucleic acid hybridization'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Antisense Plasmids Nucleic acid hybridization"

1

Preston, David R., G. Rasul Chaudhry, and Samuel R. Farrah. "Detection and identification of poliovirus in environmental samples using nucleic acid hybridization." Canadian Journal of Microbiology 36, no. 9 (1990): 664–69. http://dx.doi.org/10.1139/m90-113.

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A procedure was developed to effectively extract viral RNA from poliovirus tissue-culture lysates while eliminating the hybridization background associated with tissue cultures uninfected with poliovirus. Poliovirus cDNA cloned into a pUC vector was used as probe. Both the recombinant plasmids and the cDNA showed great specificity towards poliovirus. However, both probes hybridized with the single-stranded DNA coliphage [Formula: see text]. Tissue culture was found to be an effective method to increase the number of viruses found in environmental samples to a level detectable by hybridization
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Southern, Edwin. "Microarrays for basic studies of nucleic acid hybridization and selection of antisense reagents." Nature Genetics 23, S3 (1999): 6. http://dx.doi.org/10.1038/14210.

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Prajapati, Rama, and Álvaro Somoza. "Albumin Nanostructures for Nucleic Acid Delivery in Cancer: Current Trend, Emerging Issues, and Possible Solutions." Cancers 13, no. 14 (2021): 3454. http://dx.doi.org/10.3390/cancers13143454.

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Cancer is one of the major health problems worldwide, and hence, suitable therapies with enhanced efficacy and reduced side effects are desired. Gene therapy, involving plasmids, small interfering RNAs, and antisense oligonucleotides have been showing promising potential in cancer therapy. In recent years, the preparation of various carriers for nucleic acid delivery to the tumor sites is gaining attention since intracellular and extracellular barriers impart major challenges in the delivery of naked nucleic acids. Albumin is a versatile protein being used widely for developing carriers for nu
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Ramasamy, Kanda S., and Wilfried Seifert. "Amino Acid Nucleic Acids: Synthesis and Hybridization Properties of a Novel Class of Antisense Oligonucleotides." Nucleosides and Nucleotides 16, no. 7-9 (1997): 1519–22. http://dx.doi.org/10.1080/07328319708006220.

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Ramasamy, Kanda S., and Wilfried Seifert. "Amino acid nucleic acids: synthesis and hybridization properties of a novel class of antisense oligonucleotides." Bioorganic & Medicinal Chemistry Letters 6, no. 15 (1996): 1799–804. http://dx.doi.org/10.1016/0960-894x(96)00320-4.

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Gifford, L. K. "Identification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter molecules." Nucleic Acids Research 33, no. 3 (2005): e28-e28. http://dx.doi.org/10.1093/nar/gni024.

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Lundin, Karin E., Maroof Hasan, Pedro M. Moreno, et al. "Increased stability and specificity through combined hybridization of peptide nucleic acid (PNA) and locked nucleic acid (LNA) to supercoiled plasmids for PNA-anchored “Bioplex” formation." Biomolecular Engineering 22, no. 5-6 (2005): 185–92. http://dx.doi.org/10.1016/j.bioeng.2005.07.003.

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8

RAMASAMY, K. S., and W. SEIFERT. "ChemInform Abstract: Amino Acid Nucleic Acids: Synthesis and Hybridization Properties of a Novel Class of Antisense Oligonucleotides." ChemInform 27, no. 49 (2010): no. http://dx.doi.org/10.1002/chin.199649247.

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Romero-Palomo, Fernando, Matthias Festag, Barbara Lenz, et al. "Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats." Toxicologic Pathology 49, no. 6 (2021): 1174–92. http://dx.doi.org/10.1177/01926233211011615.

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Antisense oligonucleotides (ASOs) are chemically modified nucleic acids with therapeutic potential, some of which have been approved for marketing. We performed a study in rats to investigate mechanisms of toxicity after administration of 3 tool locked nucleic acid (LNA)-containing ASOs with differing established safety profiles. Four male rats per group were dosed once, 3, or 6 times subcutaneously, with 7 days between dosing, and sacrificed 3 days after the last dose. These ASOs were either unconjugated (naked) or conjugated with N-acetylgalactosamine for hepatocyte-targeted delivery. The ma
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10

Nass, Petra H., Leslie L. Domier, Birute P. Jakstys, and Cleora J. D'Arcy. "In Situ Localization of Barley Yellow Dwarf Virus-PAV 17-kDa Protein and Nucleic Acids in Oats." Phytopathology® 88, no. 10 (1998): 1031–39. http://dx.doi.org/10.1094/phyto.1998.88.10.1031.

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Barley yellow dwarf virus strain PAV (BYDV-PAV) RNA and the 17-kDa protein were localized in BYDV-PAV-infected oat cells using in situ hybridization and in situ immunolocalization assays, respectively. The in situ hybridization assay showed labeling of filamentous material in the nucleus, cytoplasm, and virus-induced vesicles with both sense and antisense nucleic acid probes, suggesting that the filamentous material found in BYDV-PAV-infected cells contains viral RNA. BYDV-PAV negative-strand RNA was detected before virus particles were observed, which indicates that RNA replication is initiat
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Dissertations / Theses on the topic "Antisense Plasmids Nucleic acid hybridization"

1

Svahn, Mathias G. "DNA analogs for the purpose of gene therapy /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-290-3/.

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Slaitas, Andis. "Development of a new PNA analogue as a potential antisense drug and tool for life-science studies /." Stockholm : Karolinska institutet, 2004. http://diss.kib.ki.se/2004/91-7349-642-1/.

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Nulf, Christopher J. "Peptide nucleic acid (PNA) hybridization to nucleic acid targets." 2004. http://edissertations.library.swmed.edu/pdf/NulfC121504/NulfChristopher.pdf.

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Books on the topic "Antisense Plasmids Nucleic acid hybridization"

1

A, Melton Douglas, and Cold Spring Harbor Laboratory, eds. Antisense RNA and DNA. Cold Spring Harbor Laboratory, 1988.

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