Relevant bibliographies by topics / Antisense RNA

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Antisense RNA'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Antisense RNA"

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Eguchi, Yutaka, Tateo Itoh, and Jun-ichi Tomizawa. "Antisense RNA." Annual Review of Biochemistry 60, no. 1 (June 1991): 631–52. http://dx.doi.org/10.1146/annurev.bi.60.070191.003215.

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Weitzman, Jonathan B. "Antisense RNA." Genome Biology 3 (2002): spotlight—20020125–01. http://dx.doi.org/10.1186/gb-spotlight-20020125-01.

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PESTKA, SIDNEY. "Antisense RNA." Annals of the New York Academy of Sciences 660, no. 1 (October 1992): 251–62. http://dx.doi.org/10.1111/j.1749-6632.1992.tb21077.x.

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Nordström, Kurt. "Antisense RNA." Trends in Biochemical Sciences 10, no. 6 (June 1985): 232. http://dx.doi.org/10.1016/0968-0004(85)90138-0.

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Lacombe, Julie, Ekaterina Viazovkina, Pascal N. Bernatchez, Annie Galarneau, Masad J. Damha та Martin G. Sirois. "Antisense inhibition of Flk-1 by oligonucleotides composed of 2'-deoxy-2'-fluoro-β-D-arabino- and 2'-deoxy-nucleosides". Canadian Journal of Physiology and Pharmacology 80, № 10 (1 жовтня 2002): 951–61. http://dx.doi.org/10.1139/y02-123.

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The design of new antisense oligomers with improved binding affinity for targeted RNA, while still activating RNase H, is a major research area in medicinal chemistry. RNase H recognizes the RNA–DNA duplex and cleaves the complementary mRNA strand, providing the main mechanism by which antisense oligomers elicit their activities. It has been shown that configuration inversion at the C2' position of the DNA sugar moiety (arabinonucleic acid, ANA), combined with the substitution of the 2'OH group by a fluorine atom (2' F-ANA) increases the oligomer's binding affinity for targeted RNA. In the pre
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TURGUT, Kenan. "Antisense RNA Technology." Turkish Journal of Agriculture and Forestry 20, no. 5 (January 1, 1996): 455–58. http://dx.doi.org/10.55730/1300-011x.2897.

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Liu, Zhong, and Gordon G. Carmichael. "Nuclear antisense RNA." Molecular Biotechnology 2, no. 2 (October 1994): 107–18. http://dx.doi.org/10.1007/bf02824803.

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Brantl, Sabine. "Antisense-RNA regulation and RNA interference." Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1575, no. 1-3 (May 2002): 15–25. http://dx.doi.org/10.1016/s0167-4781(02)00280-4.

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Werner, Andreas. "Natural Antisense Transcripts." RNA Biology 2, no. 2 (April 2005): 53–62. http://dx.doi.org/10.4161/rna.2.2.1852.

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Funato, Tadao, Mayu Takeda, and Mami Yoshida. "World of antisense RNA." SEIBUTSU BUTSURI KAGAKU 51, no. 3 (2007): 207–9. http://dx.doi.org/10.2198/sbk.51.207.

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Dissertations / Theses on the topic "Antisense RNA"

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Tanniche, Imen. "Correlating antisense RNA performance with thermodynamic calculations." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/49698.

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Antisense RNA (asRNA) strategies are identified as an effective and specific method for gene down-regulation at the post-transcriptional level. In this study, the major purpose is to find a correlation between the expression level and minimum free energy to enable the design of specific asRNA fragments. The thermodynamics of asRNA and mRNA hybridization were computed based on the fluorescent protein reporter genes. Three different fluorescent proteins (i) green fluorescent protein (GFP), (ii) cyan fluorescent protein (CFP) and (iii) yellow fluorescent protein (YFP) were used as reporters. Each
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Denoeux, Stanislas. "Etude de la régulation de l'expression des gènes par un ARN antisens." Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS167/document.

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Au cours de la dernière décennie, les avancées du séquençage à haut débit ont permis de caractériser un grand nombre d’ARN non codant et d’établir l’existence de transcrits “antisens” pour de nombreux gènes chez les mammifères. Cependant leur rôle dans le contrôle de l’expression des gènes “sens” auxquels ils sont associés est encore très mal connu. Mes travaux ont porté sur la caractérisation de certains aspects du mécanisme d’action des longs ARN non codants. Ils reposent sur le développement d’une approche de constructions indicatrices fluorescentes dont l’expression est suivie par cytométr
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Faridani, Omid Reza. "Studies on natural antisense RNAs and microRNAs /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-412-9/.

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Raponi, Mitch Biochemistry &amp Molecular Genetics UNSW. "Antisense RNA-mediated gene silencing in fission yeast." Awarded by:University of New South Wales. Biochemistry and Molecular Genetics, 2001. http://handle.unsw.edu.au/1959.4/18277.

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The major aims of this thesis were to investigate the influence of i) antisense gene location relative to the target gene locus (?????location effect?????), ii) double-stranded RNA (dsRNA) formation, and iii) over-expression of host-encoded proteins on antisense RNA-mediated gene regulation. To test the location effect hypothesis, strains were generated which contained the target lacZ gene at a fixed location and the antisense lacZ gene at various genomic locations including all arms of the three fission yeast chomosomes and in close proximity to the target gene locus. A long inverse-PCR proto
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Tan, Felicia. "Characterization of pilE antisense RNA in Neisseria meningitidis." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:23d8f4c4-b423-4638-986b-b6b8e3fe95ec.

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Expression of Type four pili is important for colonization and virulence in Neisseria meningitidis, which is a major causative agent of bacterial meningitis and septicaemia. Pili mediate adhesion, twitching motility, DNA uptake, and can be subject to phase and antigenic variation (Av). Pilin expression and Av may be modulated in response to environmental cues; however, the mechanisms of regulation are still unclear. This work demonstrates the identification of a novel cis-encoded RNA on the antisense (AS) strand of pilE, which encodes the major pilin subunit. The AS promoter is conserved in di
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Mitrpant, Chalermchai. "Pre-mRNA splicing manipulation via Antisense Oligomers." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2009. https://ro.ecu.edu.au/theses/421.

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Duchenne muscular dystrophy (DMD), the most common lethal neuromuscular disease in childhood, arises from protein-truncating mutations in the dystrophin gene. A deficiency in dystrophin leads to loss of the dystrophin associated protein complex (DAPC), which in turn, renders muscle fibres vulnerable to injury, and eventually leads to muscle loss, necrosis and fibrosis. Although, the dystrophin gene was identified nearly two decades ago, and extensive research has been directed at finding a therapy for DMD, to date, there is still no effective treatment available. One promising molecular approa
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Reimegård, Johan. "Making Sense of Antisense." Doctoral thesis, Uppsala universitet, Mikrobiologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131168.

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RNA is a highly versatile molecule with functions that span from being a messenger in the transfer from DNA to protein, a catalytic molecule important for key processes in the cell to a regulator of gene expression. The post-genomic era and the use of new techniques to sequence RNAs have dramatically increased the number of regulatory RNAs during the last decade. Many of these are antisense RNAs, as for example the miRNA in eukaryotes and most sRNAs in bacteria. Antisense RNAs bind to specific targets by basepairing and thereby regulate their expression. A major step towards an understanding o
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Chadwick, D. R. "Studies on antisense RNA inhibition of HIV-1 replication." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597386.

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Two vector systems were developed expressing antisense RNA (of two different sizes) complementary to three target regions in the 5' leader/LTR of HIV-1: the R (TAR) region, the primer binding site and the splice donor-packaging signal (ψ) region. After cloning these regions into an expression vector, <I>pcDNA3, </I>designed to express these sequences at high levels from the CMV IE promoter, stable constitutive expression in a T cell line was demonstrated by RT-PCR. After directly challenging these cell lines with HIV-1 at various doses cell lines expressing antisense RNA targeting the ψ-region
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Engdahl, Hilde Merete. "Natural and artificial antisense RNA : a study of inhibition of gene expression /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2000. http://epsilon.slu.se/avh/2000/91-576-5784-X.pdf.

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Dong, Shuzhi Dong Shuzhi. "I. Restriction of DNA conformation by spirocyclic annulation at C-4' II. Studies toward the enantioselective synthesis of pestalotiopsin A /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1174627553.

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Books on the topic "Antisense RNA"

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A, Melton Douglas, and Cold Spring Harbor Laboratory, eds. Antisense RNA and DNA. Cold Spring Harbor, N.Y: Cold Spring Harbor Laboratory, 1988.

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H, Murray James A., ed. Antisense RNA and DNA. New York: Wiley-Liss, 1992.

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1922-, Weiss Benjamin, ed. Antisense oligodeoxynucleotides and antisense RNA: Novel pharmacological and therapeutic agents. Roca Raton, Fla: CRC Press, 1997.

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1947-, Brakel Christine L., ed. Discoveries in antisense nucleic acids. The Woodlands, Tex: Portfolio Pub. Co., 1989.

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Arechavala-Gomeza, Virginia, and Alejandro Garanto, eds. Antisense RNA Design, Delivery, and Analysis. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2010-6.

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Ian, Phillips M., ed. Antisense technology: General methods, methods of delivery and RNA studies. San Diego, CA: Academic Press, 1999.

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Ian, Phillips M., ed. Antisense technology: General methods, methods of delivery and RNA studies. San Diego, CA: Academic Press, 2000.

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Portmann, Stefan. Kristallstrukturanalysen von RNA-Sekundärstrukturelementen und Antisense-Oligonukleotiden. [s.l.]: [s.n.], 1996.

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1966-, Hartmann Gunther, and Endres Stefan 1957-, eds. Manual of antisense methodology. Boston: Klwuer Academic, 1999.

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Ian, Phillips M., ed. Antisense technology: Applications. San Diego, CA: Academic Press, 2000.

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Book chapters on the topic "Antisense RNA"

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Scherrmann, Jean-Michel, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, et al. "Antisense RNA." In Encyclopedia of Psychopharmacology, 127. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_1062.

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Nordström, Kurt, Stanley N. Cohen, and Robert W. Simons. "Antisense RNA." In Post-transcriptional Control of Gene Expression, 231–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-60929-9_20.

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Houba-Hérin, N., and M. Inouye. "Antisense RNA." In Nucleic Acids and Molecular Biology, 210–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-46596-3_13.

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Gooch, Jan W. "Antisense RNA." In Encyclopedic Dictionary of Polymers, 875. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_13155.

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Zeiler, Brian N., and Robert W. Simons. "Control by Antisense RNA." In Regulation of Gene Expression in Escherichia coli, 67–83. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4684-8601-8_5.

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Alkan, Can, Emre Karakoç, Joseph H. Nadeau, S. Cenk Şahinalp, and Kaizhong Zhang. "RNA-RNA Interaction Prediction and Antisense RNA Target Search." In Lecture Notes in Computer Science, 152–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11415770_12.

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Harada, Kazuo. "Identification of Antisense RNA Stem-Loops That Inhibit RNA–Protein Interactions Using a Bacterial Reporter System." In RNA-RNA Interactions, 49–56. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1896-6_4.

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Georg, Jens, and Wolfgang R. Hess. "Widespread Antisense Transcription in Prokaryotes." In Regulating with RNA in Bacteria and Archaea, 191–210. Washington, DC, USA: ASM Press, 2018. http://dx.doi.org/10.1128/9781683670247.ch12.

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Wong, Dominic W. S. "Improving Tomato Quality by Antisense RNA." In The ABCs of Gene Cloning, 143–47. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-77982-9_13.

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Yang, Yaping, Jian Wang, Ruihua Zhang, and Yajun Yan. "Antisense RNA Elements for Downregulating Expression." In Methods in Molecular Biology, 23–35. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9142-6_3.

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Conference papers on the topic "Antisense RNA"

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Huang, Xin, and Huang Huang. "Abstract 2434: Regulation of HIF1a stability by an antisense RNA." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2434.

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Marzenell, Paul D., Helen Hagen, Larisa Kovbasyuk, and Andriy Mokhir. "Chemically modified phosphorothioate DNA and 2'-OMe RNA as antisense agents." In XVth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112391.

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Goodarzi, Hani, Bruce Culbertson, Kristle Garcia, and Lisa Fish. "Abstract PS19-01: A sense-antisense RNA interaction drives metabolic reprogramming in metastatic breast cancer." In Abstracts: 2020 San Antonio Breast Cancer Virtual Symposium; December 8-11, 2020; San Antonio, Texas. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.sabcs20-ps19-01.

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Park, Jeong Eun, Lee Spraggon, and Luca Cartegni. "Abstract LB-239: Induction of therapeutic soluble decoy EGFR variants by antisense manipulation of RNA processing." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-239.

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Stewart, Greg L., Katey SS Enfield, David A. Rowbotham, Roland Hubaux, Victor Martinez, Stephen Lam, and Wan Lam. "Abstract B26: OIP5-Antisense 1, a long noncoding RNA deregulated in non-small cell lung cancer." In Abstracts: AACR Special Conference on Noncoding RNAs and Cancer: Mechanisms to Medicines; December 4-7, 2015; Boston, MA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.nonrna15-b26.

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Vidarsdottir, Linda, Alireza Azimi, Jason Serviss, Christian Ingvar, Göran Jönsson, Håkan Olsson, Marianne Frostvik Stolt, et al. "Abstract B28: PTENpg1 antisense RNA mediates PTEN suppression in vemurafenib resistance and predicts clinical outcome in melanoma patients." In Abstracts: AACR Special Conference on Noncoding RNAs and Cancer: Mechanisms to Medicines; December 4-7, 2015; Boston, MA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.nonrna15-b28.

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Hsu, Jeff, Guobin He, Gourab Bhattacharjee, Tianyuan Zhou, Chris May, Brett P. Monia, Youngsoo Kim, and A. Robert MacLeod. "Abstract 2951: Potent antisense pharmacology of highly optimized antisense oligonucleotides in multiple transgenic, spontaneous and patient derived xenograft models of cancer reveals antitumor activity for the non-coding RNA MALAT-1." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2951.

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Devadoss, D., G. Daly, M. Manevski, D. Houserova, S. S. Hussain, N. B. Schmid, M. A. Salathe, G. M. Borchert, R. J. Langley, and H. S. Chand. "A Long Noncoding RNA Antisense to ICAM-1 Is Involved in Allergic Asthma Associated Hyperreactive Mucous Response of Airway Epithelial Cells." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7398.

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Cartegni, Luca, and lee Spraggon. "Abstract LB-318: Reshaping the cancer proteome: therapeutic targeting of signaling and resistance in cancer by antisense manipulation of RNA processing." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-lb-318.

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Akhmetova, E. A., O. V. Sergeeva, and T. S. Zatsepin. "N-ALKYLSULFONYL MODIFICATIONS ARE PERSPECTIVE ANALOGOUS OF PHOSPHOROTHIOATES IN ANTISENSE OLIGONUCLEOTIDES AND GUIDE RNAS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-271.

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The main disadvantages of therapeutic oligonucleotides are the off-target activity and poor stability in vivo. Major solutions of such limitations are chemical modification and targeted drug delivery. In current research we investigated the influence of alkylsulfonyl modifications on the efficacy of antisense oligonucleotides and gRNAs for CRISPR/Cas system in combination with different approaches of the selectivity improvement.
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Reports on the topic "Antisense RNA"

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Chakraborty, Srijani. The Dawn of RNA Therapeutics. Spring Library, December 2020. http://dx.doi.org/10.47496/sl.blog.19.

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Williams, Briana J. The Effect of eIF4E Antisense RNA Expression on Prostate Tumor Angiogenesis and Growth. Fort Belvoir, VA: Defense Technical Information Center, September 1999. http://dx.doi.org/10.21236/ada383175.

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Cowell, John K. Targeted Therapy of Human Breast Cancer by 2-5A-Antisense Directed Against Telomerase RNA. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada413348.

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Cowell, John K. Targeted Therapy of Human Breast Cancer by 2-5A-Antisense Directed Against Telomerase RNA. Fort Belvoir, VA: Defense Technical Information Center, December 2003. http://dx.doi.org/10.21236/ada424078.

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Cowell, John K. Targeted Therapy of Human Breast Cancer by 2-5A-Antisense Directed Against Telomerase RNA. Fort Belvoir, VA: Defense Technical Information Center, September 1999. http://dx.doi.org/10.21236/ada384610.

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Liao, Jianhua, Jingting Liu, Baoqing Liu, Chunyan Meng, and Peiwen Yuan. Effect of OIP5-AS1 on clinicopathological characteristics and prognosis of cancer patients: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2022. http://dx.doi.org/10.37766/inplasy2022.10.0118.

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Review question / Objective: According to recent studies, long non-coding RNA (lncRNAs) i.e., OPA-interacting protein 5 antisense RNA 1 (OIP5-AS1) has an important role in various carcinomas. However, its role in the cancer is contradictory. Therefore, we aimed to evaluate the link between OIP5-AS1 and cancer patients' clinicopathological characteristics and prognosis to better understand OIP5-AS1's role in cancer. Condition being studied: Reported studies have revealed that long non-coding RNA (lncRNAs) are considerably involved in crucial physiological events in several carcinomas, it can in
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Schuster, Gadi, and David Stern. Integrated Studies of Chloroplast Ribonucleases. United States Department of Agriculture, September 2011. http://dx.doi.org/10.32747/2011.7697125.bard.

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Gene regulation at the RNA level encompasses multiple mechanisms in prokaryotes and eukaryotes, including splicing, editing, endo- and exonucleolytic cleavage, and various phenomena related to small or interfering RNAs. Ribonucleases are key players in nearly all of these post-transcriptional mechanisms, as the catalytic agents. This proposal continued BARD-funded research into ribonuclease activities in the chloroplast, where RNase mutation or deficiency can cause metabolic defects and is often associated with plant chlorosis, embryo or seedling lethality, and/or failure to tolerate nutrient
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Levy, Avraham A., and Virginia Walbot. Regulation of Transposable Element Activities during Plant Development. United States Department of Agriculture, August 1992. http://dx.doi.org/10.32747/1992.7568091.bard.

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We have studied the regulation of the maize Ac and MuDR transposable elements activities during plant development. Ac was studied in an heterologous system (transgenic tobacco plants and cell suspensions) while MuDR was studied in the native maize background. The focus of this study was on the transcriptional regulation of Ac and MuDR. For Ac, the major achievements were to show that 1-It is autoregulated in a way that the Ac-encoded transposase can repress the activity of its own promoter; 2-It is expressed at low basal level in all the plant organs that were studied, and its activity is stro
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Flaishman, Moshe, Herb Aldwinckle, Shulamit Manulis, and Mickael Malnoy. Efficient screening of antibacterial genes by juvenile phase free technology for developing resistance to fire blight in pear and apple trees. United States Department of Agriculture, December 2008. http://dx.doi.org/10.32747/2008.7613881.bard.

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Objectives: The original objectives of this project were to: Produce juvenile-free pear and apple plants and examine their sensitivity to E. amylovora; Design novel vectors, for antibacterial proteins and promoters expression, combined with the antisense TFL1 gene, and transformation of Spadona pear in Israel and Galaxy apple in USA. The original objectives were revised from the development of novel vectors with antibacterial proteins combined with the TFL-1 due to the inefficiency of alternative markes initially evaluated in pear, phoshomannose-isomerase and 2-deoxyglucose-6-phosphate phospha
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Granot, David, and Noel Michelle Holbrook. Role of Fructokinases in the Development and Function of the Vascular System. United States Department of Agriculture, January 2011. http://dx.doi.org/10.32747/2011.7592125.bard.

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Plant vascular tissues are superhighways whose development and function have profound implications for productivity, yield and stress response. Preliminary studies by the PI indicated that sugar metabolism mediated by fructokinases (FRKs) has a pronounced effect on the transport properties of the xylem. The goal of this research was to determine how the main fructokinase gene, FRK2, and the only plastidic fructokinase, FRK3, influence vascular development and physiology, emphasizing processes that occur at both the cellular and organismic level. We found that both genes are expressed in vascul
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