Academic literature on the topic 'Antitussive drugs'

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Journal articles on the topic "Antitussive drugs"

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KOLOSOVA, N. G., and S. I. SHATALINA. "ANTITUSSIVE DRUGS IN CHILDREN’S PRACTICE." Medical Council, no. 9 (July 18, 2017): 76–79. http://dx.doi.org/10.21518/2079-701x-2017-9-76-79.

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Adequate choice and use of antitussive therapy in pediatrics presupposes knowing at least the two key aspects: causes of cough and the specific mechanism of the cough reflex in children, as well as the mechanisms of action of antitussive drugs used. The need for the treatment of cough as such, that is, prescription of the so-called antitussive drugs, arises mainly in children with nonproductive, dry, persistent cough. Central antitussives suppress the function of the cough center in the medulla oblongata or other associated nerve centers of the brain. The antitussive drug butamirate, often use
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Prasanna K, Thomas, Jog Pramod, Vohra Nitin R, Veligandla Krishna C, and Petare Uttam Anup. "A Newer Approach in the Management of Cough: A Review on Levodropropizine." Journal of Respiratory Diseases 1, no. 3 (2023): 1–14. http://dx.doi.org/10.14302/issn.2642-9241.jrd-23-4566.

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Safe and effective antitussive therapy remains a significant area of unmet need for cough management. Antitussive drugs are commonly used cough suppressants and include centrally acting (opioids and non-opioids) cough suppressants and peripherally acting antitussives. Authors searched PubMed, Google Scholar and additional studies from reference lists via cross-referencing to identify studies assessing levodropropizine for the treatment of cough. Of the 748 studies identified, 13 were included. Recent clinical evidence, guideline recommendations and findings from this review suggest that levodr
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Sohn, Jang Won. "Antitussive and mucoactive drugs." Journal of the Korean Medical Association 56, no. 11 (2013): 1025. http://dx.doi.org/10.5124/jkma.2013.56.11.1025.

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Muralinath, E., Devi Pooja, Chbukdhara Prasanta, et al. "Understanding the Mechanism of Action of Antitussive Drugs." Journal of Advances in Experimental Therapeutics and Neurotherapeutics 2, no. 1 (2024): 17–20. https://doi.org/10.5281/zenodo.10795828.

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<em>Coughing is a natural reflex that assists in clearing the airways of irritants and mucus. Opioid have been used as an effective antitussive compounds namely codeine and hydro condone are helpful in stopping coughing in a wide manner. By binding with mu Opioid receptors, opioid ms stop the release of neurotransmitters particularly participated I'm the cough reflex and decrease the urge to cough. Dextro methorphin ( DXM) is a non_ Opioid derivative that participates in the over the counter cough medications. If performs centrally by blocking N_ methyl_D_ asparate (NMDA) receptors and stoppin
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Dicpinigaitis, P. V., A. H. Morice, S. S. Birring, et al. "Antitussive Drugs—Past, Present, and Future." Pharmacological Reviews 66, no. 2 (2014): 468–512. http://dx.doi.org/10.1124/pr.111.005116.

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Robab, Sana, and Nida Saleem. "Search for the Natural Remedies for the Treatment of Dry Cough." Phytopharmacological Communications 3, no. 2 (2023): 125–43. http://dx.doi.org/10.55627/ppc.003.02.0386.

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Cough, also known as tussis, is a normal physiological response to any intrusion in the airway. However, this protective mechanism can turn into a nuisance if it becomes persistent, significantly impacting the social, physical, and psychological performance of a person. Standard antitussive agents like dextromethorphan (DXM), codeine, and gabapentin produce various side effects, and in some cases, cough relapse occurs as soon as drug doses are reduced. In search of better alternatives, this article delves into plant-based antitussive agents, studied in-vivo in various cough models. The cough m
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Kholodova, I. N. "Features of cough therapy in children." Meditsinskiy sovet = Medical Council, no. 17 (November 1, 2021): 102–9. http://dx.doi.org/10.21518/2079-701x-2021-17-102-109.

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This article discusses the problem of cough in children as one of the symptoms of a complicated course of acute respiratory infection. The data on the peculiarities of the course of cough in children depending on the cause, the level of damage, and age are presented. Virulence of infectious agents, immune status, and the child’s constitution may influence the development of local inflammation covering the tonsils, adenoids, pharynx, larynx. The study of respiratory problems in children remains relevant due to the need to improve therapy tactics and rehabilitation after an infection. Acute uppe
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Mutolo, Donatella, Fulvia Bongianni, Elenia Cinelli, and Tito Pantaleo. "Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit." Journal of Applied Physiology 109, no. 4 (2010): 1002–10. http://dx.doi.org/10.1152/japplphysiol.00406.2010.

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We have previously shown that the caudal nucleus tractus solitarii is a site of action of some antitussive drugs and that the caudal ventral respiratory group (cVRG) region has a crucial role in determining both the expiratory and inspiratory components of the cough motor pattern. These findings led us to suggest that the cVRG region, and possibly other neural substrates involved in cough regulation, may be sites of action of antitussive drugs. To address this issue, we investigated changes in baseline respiratory activity and cough responses to tracheobronchial mechanical stimulation followin
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Manjhi, Pramod Kumar, Sunil Kumar Singh, Chakrapani Kumar, and Akhilesh Kumar Rana. "Rational use and cost variation analysis of antitussive-expectorants available in the Indian market: a pharmacoeconomic study." International Journal of Basic & Clinical Pharmacology 10, no. 12 (2021): 1342. http://dx.doi.org/10.18203/2319-2003.ijbcp20214474.

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Background: Antitussive-expectorants are among the most frequently prescribed drugs by physicians in clinical practice. Upper respiratory tract infections, such as common cold, acute pharyngitis and acute trachea-bronchitis, are the most common of all communicable diseases and significantly increase OPD burden. This study aimed to assess the rational use, cost ratio, and percentage cost variations in different brands of the commonly prescribed antitussive-expectorants available in the Indian market.Methods: The cost of antitussive-expectorant manufactured by different pharmaceutical companies
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Kiran, Kumari* Akhil Thakur Ajeet Kumar Nikhil Kumar. "Formulation and evaluation of polyherbal antitussive." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 992–97. https://doi.org/10.5281/zenodo.11221410.

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Cough remain as untreated and symptoms of multiple disease. Cough remains a serious unmet clinical problem, both as a symptom of a range of other conditions such as asthma, chronic obstructive pulmonary disease, gastro oesophageal reflux, and as a problem in its own right in patients with chronic cough of unknown origin. Cough remains a major unmet medical need and, although the centrally acting opioids have remained the antitussive drug of choice for decades, such opioids possess many unwanted side-effects. Now a days the synthetic and novel drugs are the major source of curing any type of di
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Dissertations / Theses on the topic "Antitussive drugs"

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Paichard, Catherine. "Polymorphisme génétique de l'oxydation des médicaments cytochrome P-450 dépendants : mise en place de tests in vivo, développement de modèles in vitro." Poitiers, 1988. http://www.theses.fr/1988POIT2341.

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"Antitussive alkaloids of stemona tuberosa." Thesis, 2006. http://library.cuhk.edu.hk/record=b6074093.

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Bioassays of total alkaloids of S. tuberosa samples representing the four types of chemical profiles were conducted on guinea pigs using citric acid aerosol for inducing cough. These results demonstrated their antitussive properties and thus suggested the possibility of other antitussive alkaloids than neotuberostemonine in S. tuberosa. So it became necessary to identify the major components in the samples of S. tuberosa representing the four types of chemical profiles.<br>Bioassays on guinea pigs of the four major components of S. tuberosa demonstrated their antitussive properties. Except a
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"Chemical and pharmacological investigations into an antitussive traditional Chinese medicinal herb." 2001. http://library.cuhk.edu.hk/record=b6073708.

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Chung Hoi Sing.<br>"August 2001."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2001.<br>Includes bibliographical references (p. 186-204)<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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"A voltammetric study of some active ingredients in cough drugs." Chinese University of Hong Kong, 1987. http://library.cuhk.edu.hk/record=b5885842.

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"Chemical, pharmacological and intestinal absorption studies of stemona alkaloids from radix stemonae." Thesis, 2006. http://library.cuhk.edu.hk/record=b6074118.

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Finally, intestinal absorption of compounds A and H were also investigated by Caco-2 monolayer cell model. These results demonstrated, for the first time, that these stemona alkaloids were well absorbed in a gastrointestinal cell culture model. Furthermore, compound A was demonstrated to have a marked preference in the basolateral to apical transport direction, and such efflux (basolateral to apical) transport was inhibited by both verapamil and cyclosporine A, P-glycoprotein (P-gp) inhibitors, but not by probenecid and MK371, multidrug resistant-associated protein (MRP) inhibitors. The result
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Chen, Yi-Shyuan, and 陳怡璇. "Investigation of the Drug Use Pattern of the 「Pharmacology Category of Antitussive and Expectorant Drugs」 in Chronic Obstructive Pulmonary Disease patients associated with Emergence Visit." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/03061298954434378541.

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碩士<br>高雄醫學大學<br>藥學研究所碩士在職專班<br>94<br>This research, was to investigate the consequences of Chronic Obstructive Pulmonary Disease (COPD) Patient and Non-COPD patients, who suffered pneumonia that visit Emergency Room (ER) for further treatment, that resulted from using anti-cough, mucolytic drug and/or the combination of these two medications. Relevant research database were collected from a southern medication center from 2003 to 2005 and used SPSS version 13.0 for windows to complete the statistical work of analysis. The research objects were COPD patients with the diagnosis code, ICD-9-CM 49
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Books on the topic "Antitussive drugs"

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Widdicombe, John G., M. G. Belvisi, and K. Fan Chung. Pharmacology and therapeutics of cough. Edited by SpringerLink (Online service). Springer, 2009.

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Dextromethorphan Distribution Act of 2009: Report (to accompany H.R. 1259) (including cost estimate of the Congressional Budget Office). U.S. G.P.O., 2009.

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Decker, Patrick. Dextromethorphan: Antitussive Drug. Independently Published, 2019.

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Book chapters on the topic "Antitussive drugs"

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Page, Clive P. "Antitussive Drugs." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-21573-6_185-1.

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Page, Clive P. "Antitussive Drugs." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_185.

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Spina, D., I. McFadzean, F. K. R. Bertram, and C. P. Page. "Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugs." In Pharmacology and Therapeutics of Cough. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-79842-2_8.

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Kamikawa, Y., and Y. Shimo. "Modulating Effects of Antiasthmatic and Antitussive Drugs on Autonomic Neurotransmission in Guinea-Pig Bronchial Muscle in Vitro." In Mediators in Airway Hyperreactivity. Birkhäuser Basel, 1990. http://dx.doi.org/10.1007/978-3-0348-7379-6_7.

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Bruse, Kristy D. "Antitussive Activity." In Drug Discovery and Evaluation: Pharmacological Assays. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-05392-9_24.

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Bruse, Kristy D. "Antitussive Activity." In Drug Discovery and Evaluation: Pharmacological Assays. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27728-3_24-1.

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Nelemans, F. A. "Antiallergic and antitussive drugs." In Side Effects of Drugs Annual. Elsevier, 1990. http://dx.doi.org/10.1016/s0378-6080(05)80082-0.

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Nelemans, F. A. "Antiallergic and antitussive drugs." In Side Effects of Drugs Annual. Elsevier, 1993. http://dx.doi.org/10.1016/s0378-6080(05)80200-4.

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Nelemans, F. A. "Antiallergic and antitussive drugs." In Side Effects of Drugs Annual. Elsevier, 1994. http://dx.doi.org/10.1016/s0378-6080(05)80261-2.

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Nelemans, F. A. "Antiallergic and antitussive drugs." In Side Effects of Drugs Annual. Elsevier, 1991. http://dx.doi.org/10.1016/s0378-6080(05)80320-4.

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